isoniazid has been researched along with Abnormalities, Drug-Induced in 30 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the human teratogenic potential of isoniazid and other anti-tuberculosis drug treatment during pregnancy." | 3.71 | A population-based case-control study of the safety of oral anti-tuberculosis drug treatment during pregnancy. ( Czeizel, AE; Olsen, J; Rockenbauer, M; Sørensen, HT, 2001) |
| "The joint toxic action of three binary mixtures was determined for the embryo malformation endpoint of the aquatic FETAX (frog embryo teratogenesis assay: Xenopus) test system." | 1.28 | Initial evaluation of developmental malformation as an end point in mixture toxicity hazard assessment for aquatic vertebrates. ( Dawson, DA; Wilke, TS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (73.33) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strecker, R | 1 |
| Weigt, S | 1 |
| Braunbeck, T | 1 |
| Song, MO | 1 |
| Fort, DJ | 4 |
| McLaughlin, DL | 1 |
| Rogers, RL | 3 |
| Thomas, JH | 1 |
| Buzzard, BO | 1 |
| Noll, AM | 1 |
| Myers, NK | 1 |
| VARPELA, E | 2 |
| MATTILA, A | 1 |
| RUMLER, W | 2 |
| MOTULSKY, AG | 1 |
| SPILLANE, JD | 1 |
| LOWE, CR | 1 |
| JOERGENSEN, G | 1 |
| MACCARINI, PA | 1 |
| AGUZZOLI, RS | 1 |
| Marcus, JC | 1 |
| Snider, DE | 1 |
| Layde, PM | 1 |
| Johnson, MW | 1 |
| Lyle, MA | 1 |
| Shah, VB | 1 |
| Joshi, MV | 1 |
| Stover, EL | 2 |
| Finch, RA | 2 |
| Paul, RR | 1 |
| Czeizel, AE | 1 |
| Rockenbauer, M | 1 |
| Olsen, J | 1 |
| Sørensen, HT | 1 |
| Warkany, J | 1 |
| Mcclure, HM | 1 |
| Wilk, AL | 1 |
| Horigan, EA | 1 |
| Pratt, RM | 1 |
| Rayburn, JR | 1 |
| DeYoung, DJ | 1 |
| Bantle, JA | 1 |
| Dawson, DA | 1 |
| Wilke, TS | 1 |
| Holdiness, MR | 1 |
| Lenke, RR | 1 |
| Turkel, SB | 1 |
| Monsen, R | 1 |
| Bischoff, A | 1 |
| Fishbein, L | 1 |
| Flamm, WG | 1 |
| Castellano, MA | 1 |
| Tórtora, JL | 1 |
| Germino, NI | 1 |
| Rama, F | 1 |
| Ohanian, C | 1 |
| Bobrowitz, ID | 1 |
| Chernukh, AM | 1 |
| Ricciardi, C | 1 |
| Johnson, EM | 1 |
| Chun, YH | 1 |
7 reviews available for isoniazid and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
PHARMACOGENETICS.
Topics: Abnormalities, Drug-Induced; Animals; Dicumarol; Dogs; Drug Hypersensitivity; Drug Tolerance; Ethnol | 1964 |
[PHARMACOGENETICS].
Topics: Abnormalities, Drug-Induced; Atropine; Cleft Palate; Cortisone; Genetics; Glucosephosphate Dehydroge | 1964 |
[PHARMACOLOGY IN PREGNANCY. II].
Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Antineoplastic Agents; Female; Fetal Diseases; H | 1964 |
Treatment of tuberculosis during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antitubercular Agents; Ethambutol; Female; Hearing D | 1980 |
Teratology of the antituberculosis drugs.
Topics: Abnormalities, Drug-Induced; Animals; Antitubercular Agents; Female; Humans; Isoniazid; Pregnancy; R | 1987 |
Potential environmental chemical hazards. I. Drugs.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Rela | 1972 |
[Complex biological systems as experimental and prenatal toxicology models].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cells, | 1997 |
23 other studies available for isoniazid and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Cartilage and bone malformations in the head of zebrafish (Danio rerio) embryos following exposure to disulfiram and acetic acid hydrazide.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Bone and Bones; Cartilage; Disulfiram; Head; Isoniaz | 2013 |
Evaluation of Xenopus tropicalis as an alternative test organism for frog embryo teratogenesis assay--Xenopus (FETAX).
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Embryo, Nonmammalian; Isoniazid; Methotre | 2003 |
[TERATOGENIC EFFECT OF TUBERCULOSTATIC DRUGS].
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acid; Aminosalicylic Acids; Isoniazid; Pregnancy; Strept | 1963 |
[ON PHARMACOGENETICS].
Topics: Abnormalities, Drug-Induced; Catalase; Enzyme Inhibitors; Glucosephosphate Dehydrogenase Deficiency; | 1963 |
IATROGENIC NEUROLOGICAL DISEASES. DRUG-INDUCED NEUROLOGICAL DISORDERS.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents | 1964 |
CONGENITAL DEFECTS AMONG CHILDREN BORN TO WOMEN UNDER SUPERVISION OR TREATMENT FOR PULMONARY TUBERCULOSIS.
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acid; Aminosalicylic Acids; Communicable Diseases; Conge | 1964 |
ON THE EFFECT EXERTED BY FIRST-LINE TUBERCULOSIS MEDICINES ON THE FOETUS.
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acid; Aminosalicylic Acids; Fetus; Isoniazid; Pregnancy; | 1964 |
[PHARMACOGENETIC AND UNDESIRABLE DRUG EFFECTS].
Topics: Abnormalities, Drug-Induced; Drug Hypersensitivity; Genetics, Medical; Glucosephosphate Dehydrogenas | 1964 |
Non-teratogenicity of antituberculous drugs.
Topics: Abnormalities, Drug-Induced; Aminosalicylic Acids; Antitubercular Agents; Drug Synergism; Ethionamid | 1967 |
Alleviation of isoniazid (INH) induced malformations in chick embryos by amino acids.
Topics: Abnormalities, Drug-Induced; Amino Acids; Animals; Chick Embryo; Isoniazid; Teratogens | 1980 |
Optimization of an exogenous metabolic activation system for FETAX. I. Post-isolation rat liver microsome mixtures.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Animals; beta-Naphthoflavone; Biotransformation; | 2001 |
Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation.
Topics: Abnormalities, Drug-Induced; Animals; beta-Naphthoflavone; Biotransformation; Carbon Tetrachloride; | 2001 |
A population-based case-control study of the safety of oral anti-tuberculosis drug treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Antitubercular Agents; Case-Control Studies; Fema | 2001 |
Antituberculous drugs.
Topics: Abnormalities, Drug-Induced; Antitubercular Agents; Dihydrostreptomycin Sulfate; Ethambutol; Ethiona | 1979 |
Induction of craniofacial malformations in rhesus monkeys (Macaca mulatta) with cyclophosphamide.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Cleft Lip; Cleft Palate; Cyclophospha | 1979 |
Assessing the efficacy of an Aroclor 1254-induced exogenous metabolic activation system for FETAX.
Topics: Abnormalities, Drug-Induced; Animals; Aroclors; Biotransformation; Chlorodiphenyl (54% Chlorine); Di | 1991 |
Initial evaluation of developmental malformation as an end point in mixture toxicity hazard assessment for aquatic vertebrates.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Butyrates; Embryo, Nonmammalian; Isoniazid | 1991 |
Severe fetal deformities associated with ingestion of excessive isoniazid in early pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Female; Humans; Isoniazid; Pregnan | 1985 |
[Drug-induced polyneuropathy].
Topics: Abnormalities, Drug-Induced; Adult; Animals; Drug-Related Side Effects and Adverse Reactions; Female | 1970 |
The effects of isonicotinic acid hydrazide on the early chick embryo.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Epithelium; Isoniazid; Nerve Degeneration; Neuro | 1973 |
Ethambutol in pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Child; Child, Preschool; Chronic Disease; Drug Therapy, Combin | 1974 |
Comparative characteristics of the effect of antibiotics and other preparations on embryogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Cell Division; Chick Embryo; Ethionamid | 1965 |
In vitro assessment of abnormal developmental biology.
Topics: Abnormalities, Drug-Induced; Animals; Hydra; Regeneration; Time Factors; Vinblastine | 1985 |