Compounds > isomethyleugenol
Page last updated: 2024-08-18

isomethyleugenol and Multiple Myeloma

isomethyleugenol has been researched along with Multiple Myeloma in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19909 (18.00)18.7374
1990's5 (10.00)18.2507
2000's7 (14.00)29.6817
2010's21 (42.00)24.3611
2020's8 (16.00)2.80

Authors

AuthorsStudies
Chen, B; Liu, M; Ouyang, J; Xia, T; Xu, P; Zhao, Q1
Abramyan, T; Ackloo, S; Allali-Hassani, A; Alqazzaz, M; Arrowsmith, CH; Barsyte-Lovejoy, D; Bolotokova, A; Brown, PJ; Carvalho Machado, RA; Chau, I; Cheek, MA; Dilworth, D; Dong, A; Ferreira de Freitas, R; Gibson, E; Greenblatt, JF; Hall, NW; Hanley, RP; James, LI; Kazemzadeh, S; Keogh, MC; Khalili Yazdi, A; Kireev, D; Lei, M; Li, F; Liu, Y; Marcon, E; Marunde, MR; Mehta, N; Meiners, MJ; Min, J; Nie, DY; Owens, DDG; Popova, IK; Qin, S; Schapira, M; Szewczyk, MM; Vedadi, M; Vu, V; Zhou, M1
Bach, DH; He, J; Huang, YH; Li, Z; Lin, P; Liu, H; Wang, Z; Yang, J1
Chen, Y; Guo, Y; Jia, C; Quan, L; Wang, X; Xu, Q; Zhang, Y1
Chen, AZ; Chen, CJ; Chen, LT; Deng, JY; Huang, JQ; Huang, JY; Shangguan, XH; Wu, WH1
Feng, Y; He, A; Jia, Y; Jin, H; Kong, G; Li, Z; Liu, R; Shen, Y; Shi, L; Yang, D; Yang, Y; Yu, X; Zhang, L; Zhang, P; Zhang, X1
Aoki, S; Asano, A; Fukuda, S; Iida, S; Ito, A; Kanamori, T; Kinoshita, S; Komatsu, H; Kubo, K; Kusumoto, S; Ri, M; Tachita, T; Tohkin, M; Totani, H; Yamagata, K; Yoshida, T1
Anderson, KC; Durbin, AD; Gryder, BE; Hideshima, T; Hino, S; Johansson, C; Kawano, Y; Khan, J; Kim, Y; Kurata, K; Lauberth, S; Li, D; Masuda, T; Matsuoka, M; Minami, T; Munshi, NC; Nakao, M; Ogiya, D; Ohguchi, H; Ohtsuki, S; Oppermann, U; Park, PMC; Pei, C; Qi, J; Samur, MK; Tai, YT; Usuki, S; Wang, T; Wimalasena, VK; Zhang, X1
Dupéré-Richer, D; Licht, JD1
Bulic, M; Dupéré-Richer, D; Ezponda, T; Huang, X; Keats, J; Kelleher, N; Licht, JD; Maji, S; Nabet, B; Occhionorelli, M; Oyer, J; Patel, T; Popovic, R; Riva, A; Shah, MY; Small, EC; Tonon, G; Varghese, N; Will, CM; Zheng, Y1
Licht, JD1
Anderson, KC; Hideshima, T; Ohguchi, H1
Amini, B; Bergsagel, PL; Davis, RE; Gagel, RF; He, J; Hou, J; Koh, SP; Lee, HC; Li, Z; Lin, P; Liu, H; Liu, Z; Navone, NM; Orlowski, RZ; Starbuck, MW; Tam, BT; Tong, Q; Wang, Z; Xiao, M; Yang, J; Yi, Q; Young, KH; Zhang, Y; Zhong, Y1
Ahn, JH; Allison, DF; Bhanu, NV; Cai, L; Edmondson, RD; Garcia, BA; Groen, RWJ; Jin, J; Koss, B; Liu, H; Ma, A; Mackintosh, SG; Martens, AC; Ren, Z; Storey, AJ; Tackett, AJ; Tsai, YH; Wang, GG; Wang, P; Zheng, D1
Campani, V; Caraglia, M; De Rosa, G; Di Martino, MT; Galeone, A; Gallo Cantafio, ME; Gullà, A; Misso, G; Scognamiglio, I; Tagliaferri, P; Tassone, P; Virgilio, A1
Aronson, LI; Davies, FE; Fok, JH; Hanrahan, SJ; Kaiser, MF; Mirabella, F; Morgan, GJ; Murison, A; Pawlyn, C; Thompson, AJ; Walker, BA; Wardell, CP1
Ishida, T1
Canterbury, J; Compton, PD; Fellers, RT; Fornelli, L; Kelleher, NL; Licht, JD; Mullen, C; Senko, MW; Sharma, S; Thomas, PM; Zabrouskov, V; Zheng, Y1
Chen, Y; Wen, L; Yang, LJ; Yi, S; Zeng, LL; Zhang, BP; Zhang, C; Zhao, F; Zhao, J; Zhao, ZC1
Bogen, B; Furukawa, Y; Hofgaard, PO; Izumi, T; Kikuchi, J; Koyama, D; Wada, T1
Avaritt, NL; Byrum, SD; Davis, L; Mackintosh, SG; Mahmoud, F; Orr, LM; Reynolds, M; Sengupta, D; Shalin, SC; Shields, B; Tackett, AJ1
Agarwal, P; Alzrigat, M; Brown, PJ; Enroth, S; Jernberg-Wiklund, H; Jin, J; Kalushkova, A; Ma, A; Nilsson, K; Öberg, F; Österborg, A; Párraga, AA; Singh, U; Ungerstedt, J1
Athanasou, N; Bountra, C; Brennan, PE; Burgess-Brown, NA; Davies, F; England, KS; Fedorov, O; Hatch, SB; Hookway, ES; Johansson, C; Kawamura, A; La Thangue, NB; Morgan, G; Müller, S; Munro, S; Nowak, RP; Nuzzi, A; Oppermann, U; Pawlyn, C; Ruda, GF; Savitsky, P; Schofield, CJ; Strain-Damerell, C; Szykowska, A; Tumber, A; Velupillai, S; Wu, N; Yapp, C1
Holdenrieder, S; Kolligs, FT; Stieber, P1
Benetatos, L; Bourantas, KL; Crook, T; Dasoula, A; Dranitsaris, G; Hatzimichael, E; Stebbing, J1
Chen, Y; Li, R; Liu, Y; Wen, L; Zhang, C; Zhao, F1
Chen, Y; Li, R; Liu, Y; Wen, L; Zeng, LL; Zeng, R; Zhang, C; Zhao, F1
Chen, Y; Li, R; Liu, Y; Wen, L; Zeng, L; Zeng, R; Zhang, C; Zhao, F1
Adli, M; Ahmann, GJ; Anderson, KC; Ardlie, KG; Auclair, D; Baker, A; Bergsagel, PL; Bernstein, BE; Brunet, JP; Carpten, J; Chapman, MA; Cibulskis, K; Drier, Y; Fonseca, R; Gabriel, SB; Garraway, LA; Getz, G; Golub, TR; Hahn, WC; Harview, CL; Hofmeister, CC; Jagannath, S; Jakubowiak, AJ; Keats, JJ; Krishnan, A; Lander, ES; Lawrence, MS; Levy, J; Liefeld, T; Lonial, S; Mahan, S; Meyerson, M; Mfuko, B; Monti, S; Onofrio, R; Perkins, LM; Pugh, TJ; Rajkumar, SV; Ramos, AH; Schinzel, AC; Siegel, DS; Sivachenko, A; Sougnez, C; Stewart, AK; Trent, J; Trudel, S; Vij, R; Voet, D; Winckler, W; Zimmerman, T1
Chim, CS; Chung, LP; Jin, DY; Lam, WW; Li, GK; Liang, R; Loong, F; So, CC; Wong, KY1
Chen, K; Cheung, P; Garcia, BA; Gozani, O; Kioi, M; Kuo, AJ; Lauring, J; Li, W; Park, BH; Shi, X; Xi, Y; Zee, BM1
Cheung, WC; Chim, CS; Fung, TK; Kwong, YL; Liang, R1
Chiusolo, P; De Stefano, V; Farina, G; Fiorini, A; Leone, G; Palladino, M; Putzulu, R; Reddiconto, G; Rossi, E; Sica, S1
Akisik, EE; Dalay, N; Deligezer, U; Erten, N1
Brown, A; Marzluff, WF; Pan, CJ1
Baenziger, JU; Mellis, SJ1
Akdag, R; Mufti, GJ; Ozbek, N; Stephenson, J1
Bergsagel, PL; Eckhardt, LA; Hines, MD; Kuehl, WM; Lieberman, SA1
Asou, H; Berenson, J; Koeffler, HP; Munker, R; Nagai, M; Said, JW; Takahara, J; Tasaka, T; Vescio, RA1
Balanzategui, A; García-Sanz, R; González, M; González-Fraile, MI; Mateos, MV; San Miguel, JF; Váquez, L1
Dammacco, F; Frassanito, MA; Gernone, A; Pellegrino, A; Vacca, A1
Alhonen, L; Hämäläinen, E; Heinonen, K; Hiltunen, H; Jänne, J; Wahlfors, J1
Hatamochi, A; Namba, M; Nishitani, K; Ohtsuki, T; Yawata, Y1
Alhonen, L; Halmekytö, M; Hirvonen, A; Jänne, J; Wahlfors, J1
Alhonen-Hongisto, L; Alitalo, K; Jänne, J; Jänne, OA; Laine, R; Leinonen, P; Sinervirta, R; Winqvist, R1
Alhonen-Hongisto, L; Jänne, J; Jänne, OA; Laine, R; Leinonen, P1
Church, GM; Ephrussi, A; Gilbert, W; Tonegawa, S1
Baenziger, J; Keller, J; Kornfeld, R; Kornfeld, S1
Shier, WT1
Buchwald, BM1

Reviews

3 review(s) available for isomethyleugenol and Multiple Myeloma

ArticleYear
Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.
    Current opinion in hematology, 2017, Volume: 24, Issue:4

    Topics: Acetylation; Antineoplastic Agents; Chromatin Assembly and Disassembly; Clinical Trials as Topic; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Molecular Targeted Therapy; Multiple Myeloma; Mutation

2017
The biological significance of histone modifiers in multiple myeloma: clinical applications.
    Blood cancer journal, 2018, 08-22, Volume: 8, Issue:9

    Topics: Acetylation; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chromatin; Clinical Trials as Topic; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Methylation; Multiple Myeloma; Protein Processing, Post-Translational; Treatment Outcome

2018
[Chromosomal abnormalities and clonal evolution in multiple myeloma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: B-Lymphocytes; Cell Differentiation; Chromosome Aberrations; Clonal Evolution; Epigenesis, Genetic; Gene Dosage; GTP Phosphohydrolases; Humans; Immunoglobulin Heavy Chains; MAP Kinase Signaling System; Membrane Proteins; Methylation; Monoclonal Gammopathy of Undetermined Significance; Multiple Myeloma; Mutation; Plasma Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); ras Proteins; Risk Factors

2014

Other Studies

47 other study(ies) available for isomethyleugenol and Multiple Myeloma

ArticleYear
PRMT5 regulates cell pyroptosis by silencing CASP1 in multiple myeloma.
    Cell death & disease, 2021, 09-16, Volume: 12, Issue:10

    Topics: Animals; Arginine; Caspase 1; Cell Line, Tumor; Cell Membrane; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multiple Myeloma; Multivariate Analysis; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Pyroptosis; RNA, Messenger; Survival Analysis; Treatment Outcome; Up-Regulation

2021
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
    Nature chemical biology, 2022, Volume: 18, Issue:1

    Topics: Cell Nucleolus; Histone-Lysine N-Methyltransferase; Methylation; Molecular Probes; Multiple Myeloma; Nucleosomes; Protein Domains; Repressor Proteins

2022
Induction of m
    Journal of experimental & clinical cancer research : CR, 2022, Jan-03, Volume: 41, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Resistance, Neoplasm; Exosomes; Humans; Membrane Glycoproteins; Methylation; Mice; Mice, Knockout; Multiple Myeloma; Nerve Tissue Proteins; RNA, Long Noncoding; Signal Transduction; Tumor Microenvironment; Up-Regulation

2022
HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma.
    Journal of translational medicine, 2022, 11-18, Volume: 20, Issue:1

    Topics: Cell Proliferation; Humans; Methylation; Multiple Myeloma; RNA, Messenger; Toll-Like Receptor 4

2022
Metformin attenuates multiple myeloma cell proliferation and encourages apoptosis by suppressing METTL3-mediated m6A methylation of THRAP3, RBM25, and USP4.
    Cell cycle (Georgetown, Tex.), 2023, Volume: 22, Issue:8

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Apoptosis; Cell Proliferation; DNA-Binding Proteins; Humans; Metformin; Methylation; Methyltransferases; Multiple Myeloma; RNA, Messenger; Transcription Factors; Ubiquitin-Specific Proteases

2023
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6.
    Cell death & disease, 2023, 08-09, Volume: 14, Issue:8

    Topics: Carcinogenesis; Cell Cycle Proteins; Cell Transformation, Neoplastic; Humans; Methylation; Multiple Myeloma; NADH Dehydrogenase; Oxidative Phosphorylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA Splicing Factors

2023
Expression, mutation, and methylation of cereblon-pathway genes at pre- and post-lenalidomide treatment in multiple myeloma.
    Cancer science, 2020, Volume: 111, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; alpha Karyopherins; Biomarkers, Tumor; Cullin Proteins; Dexamethasone; Female; Gene Expression Regulation, Neoplastic; Humans; Ikaros Transcription Factor; Immunomodulation; Lenalidomide; Male; Methylation; Middle Aged; Multiple Myeloma; Mutation; Prognosis; Progression-Free Survival; Ubiquitin-Protein Ligases

2020
Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.
    Blood cancer discovery, 2021, Volume: 2, Issue:4

    Topics: Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Genes, cdc; Humans; Lysine; Methylation; Multiple Myeloma; Proto-Oncogene Proteins c-myc; Retinoblastoma-Binding Protein 2; RNA Polymerase II

2021
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
    Cell reports, 2017, Oct-17, Volume: 21, Issue:3

    Topics: Animals; Carcinogenesis; Cell Adhesion; Cell Dedifferentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clone Cells; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Indazoles; Interferon Regulatory Factors; Lysine; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Mutation; Nuclear Proteins; Phenotype; Pyridones; Transcription, Genetic

2017
DISORDERED HISTONE METHYLATION IN HEMATOLOGICAL MALIGNANCIES THE CASE OF UTX/KDM6A.
    Transactions of the American Clinical and Climatological Association, 2018, Volume: 129

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Interferon Regulatory Factors; Methylation; Mice, Inbred C57BL; Mice, Nude; Multiple Myeloma; Mutation; Nuclear Proteins; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-myc; Xenograft Model Antitumor Assays

2018
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
    Science translational medicine, 2019, 05-29, Volume: 11, Issue:494

    Topics: Adipocytes; Adipokines; Animals; Bone Diseases; Bone Marrow; Bone Resorption; Cell Line, Tumor; Cellular Reprogramming; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Methylation; Mice; Multiple Myeloma; Osteoblasts; Osteogenesis; Polycomb Repressive Complex 2; PPAR gamma; Promoter Regions, Genetic; Remission Induction; Signal Transduction; Sp1 Transcription Factor; Up-Regulation

2019
PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.
    Blood, 2019, 10-03, Volume: 134, Issue:14

    Topics: Animals; Carcinogenesis; Cell Line, Tumor; DNA-Binding Proteins; Histones; Humans; Methylation; Mice; Multiple Myeloma; Polycomb Repressive Complex 2; Transcription Factors

2019
Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Cell Proliferation; Flow Cytometry; Humans; Lipids; Male; Methylation; Mice, SCID; MicroRNAs; Multiple Myeloma; Nucleic Acids; Particle Size; Receptors, Transferrin; Static Electricity; Transferrin; Unilamellar Liposomes

2014
A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Cell Proliferation; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 4; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Introns; Mass Spectrometry; Methylation; Multiple Myeloma; Phenotype; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Repressor Proteins; Ribonucleoproteins, Small Nuclear; RNA Processing, Post-Transcriptional; RNA Splicing; SMN Complex Proteins; Spliceosomes; Translocation, Genetic

2014
Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:3

    Topics: Cell Line, Tumor; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Proteome; Repressor Proteins; Up-Regulation

2016
Triptolide Induces Cell Apoptosis by Targeting H3K4me3 and Downstream Effector Proteins in KM3 Multiple Myeloma Cells.
    Current pharmaceutical biotechnology, 2015, Volume: 17, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Diterpenes; Epoxy Compounds; Histones; Humans; Methylation; Multiple Myeloma; Phenanthrenes

2015
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.
    The Journal of clinical investigation, 2015, Oct-26, Volume: 125, Issue:12

    Topics: Animals; Cell Adhesion; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Methylation; Mice; Multiple Myeloma; Neoplasm Proteins; Phosphorylation; Polycomb Repressive Complex 2

2015
Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:3

    Topics: Cadherins; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Neoplasm Metastasis; Protein Processing, Post-Translational; Up-Regulation

2016
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
    Oncotarget, 2016, Feb-09, Volume: 7, Issue:6

    Topics: Chromatin; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Profiling; Histones; Humans; Lysine; Methylation; Molecular Targeted Therapy; Multiple Myeloma; Polycomb-Group Proteins

2016
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
    Cell chemical biology, 2017, Mar-16, Volume: 24, Issue:3

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Glycine; HeLa Cells; Histones; Humans; Kaplan-Meier Estimate; Ketoglutaric Acids; Methylation; Multiple Myeloma; Niacinamide; Protein Isoforms; Pyridines; Retinoblastoma-Binding Protein 2; Transcription Initiation Site

2017
New horizons for diagnostic applications of circulating nucleosomes in blood?
    Clinical chemistry, 2008, Volume: 54, Issue:7

    Topics: DNA; Histones; Humans; Methylation; Multiple Myeloma; Nucleosomes; Protein Processing, Post-Translational

2008
Von Hippel-Lindau methylation status in patients with multiple myeloma: a potential predictive factor for the development of bone disease.
    Clinical lymphoma & myeloma, 2009, Volume: 9, Issue:3

    Topics: Aged; Bone Diseases; Bone Marrow Cells; CpG Islands; DNA Methylation; Female; Humans; Male; Methylation; Middle Aged; Multiple Myeloma; Neovascularization, Pathologic; Promoter Regions, Genetic; Transcription, Genetic; Von Hippel-Lindau Tumor Suppressor Protein

2009
Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro.
    Toxicology, 2010, Jan-12, Volume: 267, Issue:1-3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; G1 Phase; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Interphase; Methylation; Multiple Myeloma; Phenanthrenes; Resting Phase, Cell Cycle

2010
Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Bisbenzimidazole; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Diterpenes; DNA-Binding Proteins; Drugs, Chinese Herbal; Epoxy Compounds; Flow Cytometry; Fluorescent Dyes; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitor of Apoptosis Proteins; Methylation; Multiple Myeloma; Nuclear Proteins; Phenanthrenes; Transcription Factors

2010
Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells.
    European journal of pharmacology, 2010, Nov-10, Volume: 646, Issue:1-3

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Diterpenes; Epoxy Compounds; G2 Phase; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Multiple Myeloma; Phenanthrenes; RNA, Messenger

2010
Initial genome sequencing and analysis of multiple myeloma.
    Nature, 2011, Mar-24, Volume: 471, Issue:7339

    Topics: Amino Acid Sequence; Blood Coagulation; CpG Islands; DNA Mutational Analysis; DNA Repair; Exons; Exosome Multienzyme Ribonuclease Complex; Genome, Human; Genomics; Histones; Homeodomain Proteins; Homeostasis; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Multiple Myeloma; Mutation; NF-kappa B; Oncogenes; Open Reading Frames; Protein Biosynthesis; Protein Conformation; Proto-Oncogene Proteins B-raf; Ribonucleases; RNA Processing, Post-Transcriptional; Signal Transduction; Transcription, Genetic

2011
Epigenetic inactivation of the miR-124-1 in haematological malignancies.
    PloS one, 2011, Apr-22, Volume: 6, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase 6; Epigenesis, Genetic; Female; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methylation; MicroRNAs; Middle Aged; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; Young Adult

2011
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
    Molecular cell, 2011, Nov-18, Volume: 44, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Mice, SCID; Multiple Myeloma; Recombinant Proteins; Repressor Proteins; Signal Transduction; Transcription, Genetic; Translocation, Genetic; Xenograft Model Antitumor Assays

2011
SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway.
    Blood, 2004, Jun-15, Volume: 103, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Bone Marrow Cells; Carrier Proteins; DNA Primers; DNA-Binding Proteins; Female; Humans; Intracellular Signaling Peptides and Proteins; Janus Kinase 1; Male; Methylation; Middle Aged; Molecular Sequence Data; Multiple Myeloma; Polymerase Chain Reaction; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Repressor Proteins; Signal Transduction; STAT1 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators

2004
Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma.
    Annals of hematology, 2006, Volume: 85, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; DNA Methylation; Female; Genes, p16; Genetic Variation; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Multiple Myeloma; Polymorphism, Single Nucleotide

2006
Sequence-specific histone methylation is detectable on circulating nucleosomes in plasma.
    Clinical chemistry, 2008, Volume: 54, Issue:7

    Topics: Alu Elements; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p16; DNA; Enzyme-Linked Immunosorbent Assay; Histones; Humans; Methylation; Multiple Myeloma; Nucleosomes; Plasma; Polymerase Chain Reaction

2008
Methylation of ribonucleic acid in a cell-free system from mouse myeloma cells.
    Biochemistry, 1982, Aug-31, Volume: 21, Issue:18

    Topics: Animals; Cell Line; Cell Nucleus; Cell-Free System; Guanosine Triphosphate; Methylation; Mice; Molecular Weight; Multiple Myeloma; RNA; RNA Caps; RNA, Ribosomal; RNA, Transfer

1982
Structures of the oligosaccharides present at the three asparagine-linked glycosylation sites of human IgD.
    The Journal of biological chemistry, 1983, Oct-10, Volume: 258, Issue:19

    Topics: Amino Acid Sequence; Asparagine; Carbohydrate Conformation; Carbohydrate Sequence; Glycoside Hydrolases; Glycosides; Humans; Immunoglobulin D; Mass Spectrometry; Methylation; Multiple Myeloma; Oligosaccharides

1983
Methylation status within exon 3 of the c-myc gene as a prognostic marker in myeloma and leukaemia.
    Leukemia research, 1993, Volume: 17, Issue:3

    Topics: Acute Disease; Biomarkers, Tumor; Bone Marrow; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Exons; Genes, myc; Humans; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Methylation; Multiple Myeloma; Prognosis

1993
Coordinate silencing of myeloma-specific genes in myeloma x T lymphoma hybrids.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Sep-01, Volume: 151, Issue:5

    Topics: Cell Fusion; Cell Line; Chromosome Deletion; Chromosomes, Human; Enhancer Elements, Genetic; Gene Expression Regulation; Genes, Immunoglobulin; Humans; Hybrid Cells; Immunoglobulin Heavy Chains; Lymphoma, T-Cell; Methylation; Multiple Myeloma

1993
Methylation of the p16INK4A gene in multiple myeloma.
    British journal of haematology, 1998, Volume: 101, Issue:3

    Topics: Aged; Blotting, Southern; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Female; Gene Expression; Humans; Male; Methylation; Middle Aged; Multiple Myeloma; Polymerase Chain Reaction; Tumor Cells, Cultured

1998
Methylenetetrahydrofolate reductase genotype does not play a role in multiple myeloma pathogenesis.
    British journal of haematology, 2002, Volume: 117, Issue:4

    Topics: Case-Control Studies; Chi-Square Distribution; Gene Frequency; Genes, p16; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Multiple Myeloma; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic

2002
Multiple myeloma and mycosis fungoides in the same patient: clinical, immunologic, and molecular studies.
    Annals of hematology, 2002, Volume: 81, Issue:6

    Topics: Blotting, Western; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclin-Dependent Kinase Inhibitor p16; Cytokines; Humans; Male; Methylation; Middle Aged; Multiple Myeloma; Mycosis Fungoides; Phenotype; RNA; Skin Neoplasms; Th1 Cells; Th2 Cells

2002
Genomic hypomethylation in human chronic lymphocytic leukemia.
    Blood, 1992, Oct-15, Volume: 80, Issue:8

    Topics: Chromatography, High Pressure Liquid; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methylation; Multiple Myeloma; Ornithine Decarboxylase; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger

1992
Analysis of methylation in the c-MYC gene in five human myeloma cell lines.
    British journal of haematology, 1991, Volume: 77, Issue:2

    Topics: Aged; Aged, 80 and over; Cell Line; Female; Gene Expression; Genes, myc; Humans; Karyotyping; Male; Methylation; Middle Aged; Multiple Myeloma; Nucleic Acid Hybridization

1991
Methylation of human ornithine decarboxylase gene before transfection abolishes its transient expression in Chinese hamster ovary cells.
    Biochemical and biophysical research communications, 1989, Jul-14, Volume: 162, Issue:1

    Topics: Animals; Blotting, Southern; Cell Line; Cricetinae; Cricetulus; Female; Gene Expression Regulation; Humans; Kinetics; Methylation; Multiple Myeloma; Ornithine Decarboxylase; Ovary; Plasmids; Transfection

1989
Mouse and human ornithine decarboxylase genes. Methylation polymorphism and amplification.
    The Biochemical journal, 1987, Feb-15, Volume: 242, Issue:1

    Topics: Animals; Cells, Cultured; DNA; DNA Restriction Enzymes; Electrophoresis, Agar Gel; Gene Amplification; Humans; Leukemia; Methylation; Mice; Multiple Myeloma; Ornithine Decarboxylase; Polymorphism, Genetic; Species Specificity

1987
Chronic exposure to dexamethasone induces hypomethylation of ornithine decarboxylase genes in a human myeloma cell line.
    FEBS letters, 1987, May-04, Volume: 215, Issue:1

    Topics: Cell Line; Dexamethasone; Drug Resistance; Enzyme Induction; Gene Expression Regulation; Genes; Humans; Methylation; Multiple Myeloma; Neoplasm Proteins; Ornithine Decarboxylase; RNA, Messenger; Stimulation, Chemical

1987
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo.
    Science (New York, N.Y.), 1985, Jan-11, Volume: 227, Issue:4683

    Topics: Animals; B-Lymphocytes; Base Sequence; Cell Line; Enhancer Elements, Genetic; Genes, Regulator; Guanine; Immunoglobulin Heavy Chains; Methylation; Mice; Multiple Myeloma; RNA, Messenger; Sulfuric Acid Esters

1985
The structure of the glycopeptide of human gamma G myeloma proteins.
    The Journal of biological chemistry, 1971, May-25, Volume: 246, Issue:10

    Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Fucose; Galactose; Galactosidases; Glucosamine; Glycopeptides; Glycoside Hydrolases; Humans; Immunoglobulin G; Mannose; Mass Spectrometry; Methylation; Multiple Myeloma; Neuraminic Acids; Neuraminidase; Oligosaccharides; Oxidation-Reduction; Peptides; Periodic Acid

1971
Modification of tumour growth with a defined glycoprotein antigen.
    Nature, 1973, Jul-13, Volume: 244, Issue:5411

    Topics: Adenocarcinoma; Animals; Antibody Formation; Antigens, Neoplasm; Erythrocytes; Fishes; Glycoproteins; Histocompatibility Antigens; Immunity; Immunization; Immunization Schedule; Immunosuppression Therapy; Mammary Neoplasms, Experimental; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Multiple Myeloma; Neoplasm Transplantation; Neoplasms, Experimental; Serum Albumin, Bovine; Sheep

1973
An immunoglobulin light chain of subgroup III-1 of lambda type with a free sulfhydryl group.
    Canadian journal of biochemistry, 1971, Volume: 49, Issue:8

    Topics: Amino Acid Sequence; Ammonium Sulfate; Bence Jones Protein; Chemical Precipitation; Chromatography, Gel; Cysteine; Dansyl Compounds; Dithiothreitol; Electrophoresis; Guanidines; Humans; Immunoglobulin G; Immunoglobulins; Iodine Isotopes; Iodoacetates; Methylation; Multiple Myeloma; Myeloma Proteins; Oxidation-Reduction; Peptides; Protein Denaturation; Sulfhydryl Compounds; Tryptophan; Tyrosine; Urea; Valine

1971