isomethyleugenol has been researched along with Metastase in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (17.12) | 18.7374 |
| 1990's | 9 (8.11) | 18.2507 |
| 2000's | 10 (9.01) | 29.6817 |
| 2010's | 55 (49.55) | 24.3611 |
| 2020's | 18 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Chen, S; Chen, Z; Hu, X; Hu, Y; Lu, M; Pan, B; Shen, X; Shi, X; Sun, X; Tong, X; Xue, X | 1 |
| Chen, W; Liang, H; Liao, Z; Liu, F; Miao, H; Zhang, B; Zhang, Q; Zhang, Z | 1 |
| Boers, J; Boers, R; Brands, T; de Klein, A; Gribnau, J; Kilic, E; Mensink, H; Smit, KN; Vaarwater, J; van IJcken, WFJ; Verdijk, RM | 1 |
| Diao, H; Hao, N; Koropatnick, J; Liu, Q; Maleki Vareki, S; Min, J; Min, W; Raphael, J; Sang, Y; Wang, Z; Xiong, J; Xu, D; Zhang, Y; Zheng, X | 1 |
| Apanovich, NV; Braga, EA; Brovkina, OI; Burdennyy, AM; Dmitriev, AA; Filippova, EA; Fridman, MV; Karpukhin, AV; Kazubskaya, TP; Kushlinskii, NE; Loginov, VI; Lukina, SS; Pronina, IV; Stilidi, IS; Uroshlev, LA | 1 |
| Aydin, B; Baykal, A; Erol, T; Esendağli, G; İmamoğlu, NE; Kösemehmetoğlu, K; Taşkiran, ZE | 1 |
| Cui, Y; Dai, M; Hu, Y; Kong, W; Wang, X; Wu, H; Wu, J; Yu, B; Yu, X; Zhang, H; Zheng, Y | 1 |
| Chen, J; Chen, S; Fan, S; Fang, X; Fang, Y; Liu, G; Ma, J; Shen, P; Shen, S; Wang, S; Wu, H; Wu, Y; Xie, Z; Yang, Y | 1 |
| Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D | 1 |
| Hou, T; Li, M; Li, Y; Li, Z; Liu, C; Liu, X; Lu, X; Mao, Z; Tang, M; Wang, H; Wen, H; Yang, Q; Yang, Y; Zhao, Y; Zhu, Q; Zhu, WG | 1 |
| He, X; Hou, B; Huang, K; Huang, S; Ji, F; Ma, Z; Ruan, S; Zhang, C; Zhou, Z; Zhuang, H | 1 |
| Chen, C; Geng, W; Guo, H; Wang, Q; Wang, S; Wang, Z; Xu, K | 1 |
| Bao, Y; Du, R; Gao, W; Li, J; Luo, N; Shen, W; Wang, J; Yang, W; Zhang, X | 1 |
| Chen, H; Fang, Q | 1 |
| Du, W; Duan, R; Guo, W | 1 |
| Feng, Y; Gong, J; Guo, J; Guo, X; He, C; He, R; Jiang, J; Li, M; Li, X; Liu, J; Miao, J; Peng, F; Qin, R; Shi, C; Tian, R; Wang, M; Wei, W; Xie, Y; Xu, S; Xu, X; Yu, S; Zhang, H; Zhao, Y; Zhu, F | 1 |
| Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F | 1 |
| Bai, J; Dong, M; Fan, D; Gao, Y; Hou, P; Huang, B; Li, H; Li, M; Li, Z; Liu, H; Lu, J; Pan, ZQ; Wang, D; Wang, Y; Zheng, J | 1 |
| Bai, J; Chen, X; Hou, P; Li, M; Li, Z; Tang, A; Wang, D; Wang, W; Zheng, J | 1 |
| Ding, X; Li, D; Peng, Y; Wang, X; Wang, Y; Wu, Y; Yang, A; Yang, P; Yin, H; Yu, Y; Zhang, J; Zhang, R; Zhang, X | 1 |
| Cao, D; Ding, H; Hou, J; Huang, B; Lin, C; Liu, J; Liu, L; Liu, X; Liu, Y; Lu, J; Wang, G; Zhang, N; Zhang, X; Zhang, Y | 1 |
| Bao, H; Cai, Z; Guan, X; Ji, Y; Liu, H; Qin, G; Wang, X; Wei, A | 1 |
| Feng, B; Li, C; Su, Z; Sun, C; Tang, L; Zheng, G; Zhu, Y | 1 |
| Chen, G; Gong, S; Hao, L; Jia, C; Jiang, J; Li, B; Li, L; Liu, F; Liu, P; Ma, F; Ong, IM; Wang, Y; Xu, W; Zeng, H | 1 |
| DeBerardinis, RJ; Hu, Z; Huang, F; Morrison, SJ; Shi, X; Tasdogan, A | 1 |
| Kim, SY; Lee, HS; Lee, SJ; Shin, KS | 1 |
| Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G | 1 |
| Braga, EA; Burdennyy, AM; Dmitriev, AA; Filippova, EA; Kazubskaya, TP; Khodyrev, DS; Kushlinskii, NE; Kushlinsky, DN; Loginov, VI; Pronina, IV; Utkin, DO | 1 |
| Chen, W; Du, X; Heng, B; Lai, C; Mo, S; Shi, L; Su, Z | 1 |
| Feng, D; Gao, J; Hou, Y; Huang, W; Leng, S; Liu, R; Qiu, R; Shi, H; Sun, G; Teng, X; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zheng, Y | 1 |
| Chun, YS; Kang, J; Lee, GY; Lee, M; Park, JW; Shin, HW; Shin, SH | 1 |
| Bai, C; Kou, L; Li, M; Li, W; Mo, P; Peng, K; Yu, C; Yu, L | 1 |
| Li, L; Li, R; Wang, Y | 1 |
| Cong, L; Feng, M; Wang, H; Yang, G; You, L; Zhang, T; Zhao, Y; Zheng, L | 1 |
| Kakkar, N; Kaushal, K; Kumar, A; Kumari, N; Prasad, R; Ram, S; Sharma, U; Singh, SK | 1 |
| Bachvarov, D; Bachvarova, M; Gregoire, J; Keita, M; Morin, C; Plante, M; Renaud, MC; Sebastianelli, A; Trinh, XB | 1 |
| Arnold, P; Balwierz, PJ; Christofori, G; Meyer-Schaller, N; Pachkov, M; Schübeler, D; Tiwari, N; Tiwari, VK; van Nimwegen, E; Waldmeier, L | 1 |
| Bernasconi, MJ; Frederick, DT; Gunda, V; Parangi, S; Wargo, JA | 1 |
| Beninato, T; Crowley, MJ; Elemento, O; Evans, T; Fahey, TJ; Finnerty, B; Kleiman, DA; Kumar, R; Lieberman, MD; Liu, YF; Panarelli, NC; Seandel, M; Sultan, S; Zarnegar, R | 1 |
| Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y | 1 |
| Brown, K; Deng, C; Huang, S; Pampo, C; Qiu, Y; Salz, T; Siemann, D | 1 |
| Chou, KH; Hsu, C; Huang, WF; Huang, YL; Lin, IH; Lin, LI; Lin, YH; Lin, YM; Lu, JW; Ou, DL; Shen, CK; Tzeng, TY; Wang, WP; Wu, PC; Yang, JY | 1 |
| Deng, J; Guo, W; He, Y; Hu, J; Liao, Y; Liu, J; Liu, S; Song, H; Sun, B; Wang, X; Wang, Y; Wu, Y; Xu, D; Ye, D; Yin, H; Yu, W; Zhang, L; Zhang, Z; Zhong, S; Zhou, BP | 1 |
| Castle, EP; Champion, MD; Dykema, K; Ho, TH; Hoang, A; Hung, MC; Jonasch, E; Joseph, RW; Monzon, FA; Nunez-Nateras, R; Park, IY; Parker, AS; Qiao, W; Tamboli, P; Tannir, NM; Teh, BT; Tong, P; Walker, CL; Wang, J; Yan, H; Zhao, H | 1 |
| Ding, X; Fan, J; Fan, X; Ge, S; He, J; Hoffman, AR; Jia, R; Ni, H; Pan, H; Qian, G; Wen, X; Xing, Y; Zhang, H | 1 |
| Avaritt, NL; Byrum, SD; Davis, L; Mackintosh, SG; Mahmoud, F; Orr, LM; Reynolds, M; Sengupta, D; Shalin, SC; Shields, B; Tackett, AJ | 1 |
| Hou, L; Li, M; Li, Q; Yu, Y; Zhang, D | 1 |
| Choi, C; Hong, BJ; Kim, MY; Lee, J; Park, WY | 1 |
| Ishimura, A; Oktyabri, D; Suzuki, T; Tange, S; Terashima, M | 1 |
| Feng, Q; Gao, T; Lei, Q; Shi, Y; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, M; Yang, F; Ye, T; You, X; Yu, L; Zhang, L; Zhu, Y | 1 |
| Cheng, SY; Fu, L; Gao, D; Wu, H; Zhang, L; Zhao, Y | 1 |
| Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L | 1 |
| Giaccia, AJ | 1 |
| Chen, X; Fan, LN; Huo, Y; Ji, G; Li, YF; Qin, WW; Wang, T; Wang, W; Wen, WH; Xi, WJ; Xiao, X; Yang, AG; Yang, F | 1 |
| Cackowski, FC; Decker, AM; Franceschi, RT; Jung, Y; Lee, E; Li, Y; Pienta, KJ; Taichman, RS; Wang, J; Yumoto, K | 1 |
| Blum, G; Bothwell, IR; Kapilashrami, K; Linscott, JA; Luo, M; Senevirathne, C; Wang, Z | 1 |
| Dong, W; Jia, L; Li, N; Ma, X; Miao, Y; Su, Z; Zhao, L; Zhou, H | 1 |
| Chow, EK; Lim, JJ; Toh, TB | 1 |
| Guo, X; Huang, W; Mei, H; Wang, F; Xia, M; Yao, L; Zhang, Q | 1 |
| Hwang, D; Kim, TY; Park, HR; Shin, KS; Suh, HJ; Yu, KW | 1 |
| Issa, JP | 1 |
| Chen, BH; Hsu, HS; Jin, JS; Lee, SC; Sun, GH; Tung, HJ; Tzao, C; Yu, CP | 1 |
| Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J | 1 |
| Kimura, T; Matsuura, N; Sugitachi, A; Yamamoto, K | 1 |
| Argani, P; Brzoska, P; Chang, HY; Gupta, RA; Horlings, HM; Hung, T; Kim, J; Kong, B; Li, R; Rinn, JL; Shah, N; Sukumar, S; Tsai, MC; van de Vijver, MJ; Wang, KC; Wang, Y; West, RB; Wong, DJ | 1 |
| Dalay, N; Darendeliler, E; Deligezer, U; Dizdar, Y; Holdenrieder, S; Kovancilar, M; Yaman, F | 1 |
| Ye, D; Zhu, Y | 1 |
| Berger, SL; Liu, Z; Merlino, G; Xiong, J; Yu, Y; Zeng, P | 1 |
| Anastassiou, D; Kim, H; Varadan, V; Watkinson, J | 1 |
| Dong, Z; Du, J; Huang, B; Jiang, H; Kong, C; Li, L; Lu, J; Ou, Z; Shao, Z; Zhang, Y; Zhu, S | 1 |
| Cai, MY; Guan, XY; Kong, LL; Kung, HF; Rao, HL; Tong, ZT; Wen, ZZ; Xie, D; Zeng, YX; Zhu, W | 1 |
| Chan, TH; Chen, L; Guan, XY; Kong, KL; Kwong, DL; Law, SY; Li, Y; Qin, YR | 1 |
| Gui, B; Han, X; Li, Q; Shang, Y; Shi, L; Wang, J; Yao, Z; Yu, W; Zhang, D | 1 |
| Bastian, PJ; Ellinger, J; Gütgemann, I; Heukamp, LC; Hofstädter, F; Kahl, P; Müller, SC; Rogenhofer, S; von der Gathen, J; von Ruecker, A; Walter, B | 1 |
| Chen, L; Cheng, X; Ji, T; Li, J; Li, Y; Liu, X; Liu, Y; Xiao, Z; Yao, S; Zheng, P; Zhou, J | 1 |
| Kong, HK; Park, JH; Yoon, S | 1 |
| Cock-Rada, A; Weitzman, JB | 1 |
| Horiuchi, A; Konishi, I | 1 |
| Bu, XM; Zhang, N; Zhao, CH | 1 |
| Pulukuri, SM; Rao, JS | 1 |
| Chen, CD; Han, G; Lin, H; Xiang, Y; Xu, L; Zhu, Z | 1 |
| Engel, D; Levovich, I; Makarovsky, I; Nudelman, A; Rephaeli, A; Sochotnikov, S; Tarasenko, I; Tarasenko, N | 1 |
| Forchhammer, J; Olsson, L | 1 |
| Carlow, DA; Elliott, BE; Frost, P; Kerbel, RS; Liteplo, R | 1 |
| Nicolson, GL | 1 |
| Georgiev, G; Grigorian, M; Lukanidin, E; Tkatch, T; Tulchinsky, E | 1 |
| Schwab, M | 1 |
| Ishida, K; Maesawa, C; Nishizuka, S; Ogasawara, S; Saito, K; Sakata, K; Sato, N; Satodate, R; Tamura, G; Terashima, M | 1 |
| Ashida, T; Fujiki, T; Fujiya, M; Honda, M; Kohgo, Y; Saitoh, Y; Tanabe, H; Watari, J | 1 |
| Ford, HL; Grigorian, M; Kramerov, D; Lukanidin, E; Reshetnyak, E; Tulchinsky, E; Zain, S | 1 |
| Grigorian, MS; Gural', NI; Kramerov, DA; Lukanidin, EM; Reshetniak, EIu; Tul'chinskiĭ, EM | 1 |
| Rogers, S; Royds, JA; Sharrard, RM; Shorthouse, AJ | 1 |
| Bock, KW; Köchel, H; Marx, D; Münzel, P; Schauer, A | 1 |
| Bassin, RH; Rimoldi, D; Samid, D; Srikantan, V; Wilson, VL | 1 |
| Akedo, H; Ashida, Y; Inoue, H; Isoai, A; Kido, J; Kumagai, H; Shinkai, K | 1 |
| Greig, R; Kline, T; Mallon, F; Poste, G; Trainer, DL | 1 |
| Everett, CA; Hart, IR; Ormerod, EJ | 1 |
| Everett, CA; Finch, M; Hart, IR; Ormerod, EJ | 1 |
| Hamada, J; Hosokawa, M; Ishikawa, M; Kobayashi, H; Okada, F | 1 |
| Barzilay, J; Eisenbach, L; Feldman, M; Kushtai, G | 1 |
| Ebralidze, AK; Grigorian, MS; Lukanidin, EM; Revazova, ES; Senin, VM; Tyl'chinskiĭ, EM | 1 |
| Guirguis, RA; Liotta, LA; Schiffmann, E | 1 |
| Frost, P; Kendal, WS | 1 |
| Fidler, IJ; Frost, P | 1 |
| Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Karlsson, KA; Pascher, I; Samuelsson, BE | 1 |
| Arita, H; Kawanami, J | 1 |
| Lu, T; Nelson, JH; Sheid, B | 1 |
| Hiraki, S | 1 |
| Bodey, GP; Brodovsky, HS; Freireich, EJ; Isassi, AA; Samuels, ML | 1 |
| Clapp, NK; Craig, AW; Toya, RE | 1 |
11 review(s) available for isomethyleugenol and Metastase
| Article | Year |
|---|---|
The role of RNA m
Topics: 5-Methylcytosine; Animals; Humans; Methylation; Neoplasm Metastasis; RNA | 2021 |
Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer.
Topics: Adenosine; Cell Physiological Phenomena; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Methylation; Methyltransferases; Models, Biological; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Biosynthesis; Radiation Tolerance; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Neoplasm | 2020 |
EZH2: a novel target for cancer treatment.
Topics: Adenosine; Antineoplastic Agents; Benzamides; Biphenyl Compounds; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Histone Code; Histones; Humans; Methylation; Morpholines; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship; Transcriptional Activation; Tumor Microenvironment | 2020 |
SFRP1 Promoter Methylation and Renal Carcinoma Risk: A Systematic Review and Meta-Analysis.
Topics: Carcinoma, Renal Cell; Confidence Intervals; Humans; Incidence; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Membrane Proteins; Meta-Analysis as Topic; Methylation; Neoplasm Metastasis; Neoplasm Staging; Odds Ratio; Promoter Regions, Genetic; Risk | 2018 |
Epigenetics in cancer stem cells.
Topics: Acetylation; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Epigenomics; Histones; Humans; Methylation; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Signal Transduction | 2017 |
The methylation landscape of tumour metastasis.
Topics: Animals; DNA Methylation; Epigenomics; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplasm Metastasis; Neoplasms | 2013 |
[Mechanism of ovarian cancer metastasis--changes in E-cadherin expression].
Topics: Cadherins; Cell Adhesion; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methylation; Neoplasm Metastasis; Ovarian Neoplasms; Promoter Regions, Genetic; Transcription Factors | 2004 |
Possible epigenetic mechanisms of tumor progression: induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment.
Topics: Animals; Azacitidine; DNA; Ethyl Methanesulfonate; Humans; Mammary Neoplasms, Experimental; Methylation; Methylnitronitrosoguanidine; Models, Genetic; Mutation; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Phenotype; Stem Cells | 1984 |
Generation of phenotypic diversity and progression in metastatic tumor cells.
Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; DNA; Humans; Methylation; Mutation; Neoplasm Metastasis; Neoplasms; Phenotype | 1984 |
Tumor autocrine motility factor.
Topics: Cell Line; Cell Movement; Glucose-6-Phosphate Isomerase; Humans; Melanoma; Membrane Proteins; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Oncogenes | 1986 |
Genetic instability and tumor progression.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Clone Cells; DNA, Neoplasm; Gene Expression Regulation; Humans; Methylation; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Oncogenes; Precancerous Conditions | 1986 |
100 other study(ies) available for isomethyleugenol and Metastase
| Article | Year |
|---|---|
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Topics: 5-Methylcytosine; Aged; Amino Acid Sequence; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Protein Stability; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Stomach Neoplasms; Subcellular Fractions; Sumoylation; Ubiquitins | 2021 |
Genome-wide aberrant methylation in primary metastatic UM and their matched metastases.
Topics: DNA Mutational Analysis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Methylation; Neoplasm Metastasis; Phosphoproteins; RNA Splicing Factors; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Uveal Neoplasms | 2022 |
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
Topics: Animals; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Demethylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Histones; Lung Neoplasms; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Transcription Factors | 2021 |
Aberrant Methylation of 20 miRNA Genes Specifically Involved in Various Steps of Ovarian Carcinoma Spread: From Primary Tumors to Peritoneal Macroscopic Metastases.
Topics: Carcinoma; Carcinoma, Ovarian Epithelial; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Machine Learning; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Peritoneum; Prognosis; Recurrence; Transcriptome | 2022 |
Primary tumor resection for initially staged IV breast cancer: An emphasis on programmed death-ligand 1 expression, promoter methylation status, and survival.
Topics: B7-H1 Antigen; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Programmed Cell Death 1 Receptor; Real-Time Polymerase Chain Reaction; Retrospective Studies; Turkey | 2019 |
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Topics: Acetylation; Animals; Azepines; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histocompatibility Antigens; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Snail Family Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta | 2019 |
CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling.
Topics: 3' Untranslated Regions; Animals; ATPases Associated with Diverse Cellular Activities; beta Catenin; Bone Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Disease Progression; DNA Helicases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Lymphoid Enhancer-Binding Factor 1; Methylation; Mice; MicroRNAs; Myosins; Neoplasm Metastasis; Osteosarcoma; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA, Circular; Wnt Signaling Pathway | 2019 |
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2019 |
CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasis.
Topics: Acetylation; Animals; Cell Line, Tumor; Chromatin Immunoprecipitation; Colorectal Neoplasms; Disease Progression; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Methylation; Mice; Mice, Nude; Neoplasm Metastasis; Peptide Fragments; Plasmids; Protein Processing, Post-Translational; Sialoglycoproteins; Signal Transduction; Ubiquitin-Protein Ligases | 2020 |
YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Prognosis; RNA-Binding Proteins; RNA, Messenger; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured | 2020 |
Ibuprofen mediates histone modification to diminish cancer cell stemness properties via a COX2-dependent manner.
Topics: A549 Cells; Acetylation; Animals; Cell Line, Tumor; Cyclooxygenase 2; Drug Resistance, Neoplasm; Female; Hep G2 Cells; Histone Deacetylases; Histones; Humans; Ibuprofen; Intercellular Adhesion Molecule-3; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Random Allocation | 2020 |
The significance of m6A RNA methylation regulators in predicting the prognosis and clinical course of HBV-related hepatocellular carcinoma.
Topics: Adenine; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Gene Expression Profiling; Hepatitis B; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; RNA | 2020 |
Upregulation of METTL14 mediates the elevation of PERP mRNA N
Topics: Adenine; Animals; Binding Sites; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Heterografts; Humans; Kaplan-Meier Estimate; Membrane Proteins; Methylation; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Protein Binding; RNA Stability; RNA, Messenger | 2020 |
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2.
Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms | 2020 |
Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Topics: Animals; Breast Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Phosphorylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; Ubiquitination | 2020 |
Macrophages-stimulated PRMT1-mediated EZH2 methylation promotes breast cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Interleukin-6; Intracellular Signaling Peptides and Proteins; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Protein Stability; Protein-Arginine N-Methyltransferases; Repressor Proteins; Tumor Microenvironment; Ubiquitination; Xenograft Model Antitumor Assays | 2020 |
RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Cell Polarity; Cell Proliferation; Cellular Reprogramming; Cytokines; Gene Deletion; Gene Expression Regulation; Lung Neoplasms; Macrophages; Melanoma, Experimental; Methylation; Methyltransferases; Mice, Knockout; Myeloid Cells; Neoplasm Metastasis; NF-kappa B; Programmed Cell Death 1 Receptor; Repressor Proteins; RNA-Binding Proteins; RNA, Neoplasm; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Tumor Microenvironment | 2021 |
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.
Topics: Arginine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lysine; Methylation; Mitochondria; Neoplasm Metastasis; Organoids; Oxidative Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2021 |
Potential role of m6A RNA methylation regulators in osteosarcoma and its clinical prognostic value.
Topics: Adolescent; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Bone Neoplasms; Child; Female; Forecasting; Gene Expression; Genetic Association Studies; Humans; Male; Methylation; Methyltransferases; Neoplasm Metastasis; Osteosarcoma; Prognosis; Regression Analysis; Risk; RNA; RNA-Binding Proteins; Signal Transduction | 2021 |
Basil polysaccharide attenuates hepatocellular carcinoma metastasis in rat by suppressing H3K9me2 histone methylation under hepatic artery ligation-induced hypoxia.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Proliferation; Epithelial-Mesenchymal Transition; Hepatic Artery; Histones; Ligation; Liver Neoplasms; Male; Methylation; Neoplasm Metastasis; Neoplasm Proteins; Ocimum basilicum; Polysaccharides; Rats, Wistar; RNA, Messenger | 2018 |
PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis.
Topics: Animals; Calcium; Carcinogenesis; CARD Signaling Adaptor Proteins; Carrier Proteins; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endoplasmic Reticulum; Female; Glycolysis; Guanylate Cyclase; HEK293 Cells; Humans; Inositol 1,4,5-Trisphosphate Receptors; MCF-7 Cells; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasm Metastasis; Oxidative Phosphorylation; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2017 |
The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.
Topics: Animals; Cell Movement; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Histone-Lysine N-Methyltransferase; Histones; Humans; Indoles; Melanoma; Metabolome; Metabolomics; Methylation; Mice; Mice, Inbred NOD; Neoplasm Metastasis; Principal Component Analysis; Protein Methyltransferases; Proto-Oncogene Proteins B-raf; Pyridones; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous | 2017 |
Immunostimulatory and anti-metastatic activity of polysaccharides isolated from byproducts of the corn starch industry.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antineoplastic Agents; Chemical Fractionation; Cytokines; Female; Glycosides; Granzymes; Industrial Waste; Industry; Interferon-gamma; Killer Cells, Natural; Lymphocyte Activation; Macrophages, Peritoneal; Methylation; Mice, Inbred BALB C; Neoplasm Metastasis; Polysaccharides; Starch | 2018 |
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1 | 2018 |
Novel miRNA genes deregulated by aberrant methylation in ovarian carcinoma are involved in metastasis.
Topics: Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; CpG Islands; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histology; Humans; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; Up-Regulation | 2018 |
PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cadherins; Carcinogenesis; Carcinoma; Cell Line; Cell Proliferation; Cullin Proteins; DNA-Binding Proteins; F-Box-WD Repeat-Containing Protein 7; Female; HEK293 Cells; Histones; Humans; Methylation; Mice; Neoplasm Metastasis; Polycomb-Group Proteins; Protein-Arginine N-Methyltransferases; Transcription Factors; Transcription, Genetic | 2018 |
Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway.
Topics: Acetylation; Adenocarcinoma; Cell Movement; Epithelial-Mesenchymal Transition; HEK293 Cells; Humans; Male; Methylation; Neoplasm Metastasis; Nucleolin; p300-CBP Transcription Factors; PC-3 Cells; Phosphoproteins; Prostatic Neoplasms; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Repressor Proteins; RNA-Binding Proteins; Serine Endopeptidases; Trans-Activators; Transcriptional Regulator ERG | 2018 |
Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.
Topics: Animals; beta Catenin; Cell Movement; Cell Proliferation; Cell Survival; Chloroquinolinols; Colorectal Neoplasms; Cyclin D1; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methylation; Mice; Mice, Knockout; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Transcription, Genetic; Tumor Stem Cell Assay; Wnt Signaling Pathway | 2019 |
Identification of selective and reversible LSD1 inhibitors with anti-metastasis activity by high-throughput docking.
Topics: Cell Line, Tumor; Demethylation; Enzyme Inhibitors; Histone Demethylases; Histones; Humans; Lysine; Methylation; Molecular Docking Simulation; Neoplasm Metastasis; Neoplasms; Structure-Activity Relationship | 2019 |
Integrated analysis of gene expression and methylation profiles of novel pancreatic cancer cell lines with highly metastatic activity.
Topics: Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Methylation; Mice, Nude; Mice, SCID; MicroRNAs; Neoplasm Metastasis; Pancreatic Neoplasms; RNA, Long Noncoding; RNA, Messenger | 2019 |
Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications.
Topics: Apoptosis; Biomarkers, Tumor; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Demethylases; Histones; Humans; Kidney Neoplasms; Methylation; Methyltransferases; Neoplasm Metastasis; Prognosis; Retinoblastoma-Binding Protein 2 | 2019 |
The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 2 Subunit; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; RNA Interference; RNA, Small Interfering | 2013 |
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming.
Topics: Animals; Cell Line; Cell Movement; Cell Survival; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylation; Mice; Neoplasm Metastasis; Polycomb Repressive Complex 2; Promoter Regions, Genetic; SOXC Transcription Factors; Transcription, Genetic | 2013 |
A potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expression.
Topics: Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Coculture Techniques; Cytoplasm; Decitabine; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Granzymes; Humans; Immunotherapy; Interferon-gamma; Lymphocytes; Membrane Proteins; Methylation; Mice; Mice, SCID; Neoplasm Metastasis; Polymerase Chain Reaction; Receptors, Antigen, T-Cell; RNA, Messenger; Thyroid Neoplasms | 2014 |
Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors.
Topics: Adult; Aged; Blood Vessels; Carcinoid Tumor; CpG Islands; Digestive System Neoplasms; Female; Gene Silencing; Humans; Ki-67 Antigen; Male; Methylation; Middle Aged; Mitotic Index; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Risk Factors; Sensitivity and Specificity; Ubiquitin Thiolesterase | 2014 |
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.
Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors | 2014 |
Histone Methyltransferase hSETD1A Is a Novel Regulator of Metastasis in Breast Cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epigenesis, Genetic; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Matrix Metalloproteinases; MCF-7 Cells; Methylation; Mice; Neoplasm Metastasis; Up-Regulation | 2015 |
H3K9 histone methyltransferase, KMT1E/SETDB1, cooperates with the SMAD2/3 pathway to suppress lung cancer metastasis.
Topics: Animals; Annexin A2; Cell Line, Tumor; Epigenesis, Genetic; Gene Silencing; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Methylation; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Methyltransferases; Signal Transduction; Smad2 Protein; Smad3 Protein; Xenograft Model Antitumor Assays; Zebrafish | 2014 |
G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma.
Topics: Antigens, CD; Cadherins; Carcinoma, Squamous Cell; Cell Movement; Epithelial-Mesenchymal Transition; Flow Cytometry; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymphatic Metastasis; Methylation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplastic Stem Cells; Prognosis; Squamous Cell Carcinoma of Head and Neck; Stem Cells; Transforming Growth Factor beta; Treatment Outcome; Wound Healing | 2015 |
High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma.
Topics: Carcinoma, Renal Cell; Chromatin Immunoprecipitation; Cohort Studies; Histones; Humans; Kidney Neoplasms; Lysine; Methylation; Neoplasm Metastasis | 2016 |
Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.
Topics: Calcium-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; HT29 Cells; Humans; Methylation; Neoplasm Metastasis; RNA, Long Noncoding | 2015 |
Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma.
Topics: Cadherins; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Multiple Myeloma; Neoplasm Metastasis; Protein Processing, Post-Translational; Up-Regulation | 2016 |
SET8 induces epithelial‑mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1.
Topics: Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Male; Methylation; Neoplasm Metastasis; Prostatic Neoplasms; Protein Binding; Transcription Factors; Transcription, Genetic; Vimentin; Zinc Finger E-box-Binding Homeobox 1 | 2016 |
H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis.
Topics: Animals; Cell Line, Tumor; Heterografts; Humans; Jumonji Domain-Containing Histone Demethylases; Melanoma; Melanoma, Cutaneous Malignant; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; NF-kappa B; Signal Transduction; Skin Neoplasms; Tumor Microenvironment | 2016 |
DOT1L histone methyltransferase regulates the expression of BCAT1 and is involved in sphere formation and cell migration of breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Methylation; Methyltransferases; Neoplasm Metastasis; Transaminases | 2016 |
Selective inhibition of EZH2 by ZLD1039 blocks H3K27 methylation and leads to potent anti-tumor activity in breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Intracellular Space; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Polycomb Repressive Complex 2; Pyridones; Quinolones; Small Molecule Libraries; Transcriptional Activation; Xenograft Model Antitumor Assays | 2016 |
Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals.
Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; DNA; Hedgehog Proteins; Histone-Lysine N-Methyltransferase; Humans; Kruppel-Like Transcription Factors; Methylation; Mice; Neoplasm Metastasis; Nerve Tissue Proteins; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Signal Transduction; Zinc Finger Protein Gli3 | 2016 |
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.
Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes | 2016 |
A New Chromatin-Cytoskeleton Link in Cancer.
Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin | 2016 |
Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Cytoskeletal Proteins; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Histones; Humans; LIM Domain Proteins; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Transplantation, Heterologous | 2016 |
DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis.
Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epithelial-Mesenchymal Transition; Gene Silencing; Histones; Homeodomain Proteins; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Methylation; Mice; Neoplasm Metastasis; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Kinase C-alpha; Repressor Proteins; RNA Interference; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger E-box Binding Homeobox 2 | 2016 |
Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.
Topics: Binding, Competitive; Catalysis; Cell Cycle; Computer Simulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Isotopes; Kinetics; Lysine; Methylation; Models, Molecular; Models, Theoretical; Neoplasm Metastasis; Peptides; Protein Structure, Secondary; S-Adenosylmethionine; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2016 |
Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4.
Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycomics; Humans; Methylation; MicroRNAs; Middle Aged; N-Acetylneuraminic Acid; Neoplasm Metastasis; Polysaccharides; Sialyltransferases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Long noncoding RNA HOTAIR promotes metastasis of renal cell carcinoma by up-regulating histone H3K27 demethylase JMJD3.
Topics: Apoptosis; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Kaplan-Meier Estimate; Kidney Neoplasms; Methylation; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; Snail Family Transcription Factors; Up-Regulation | 2017 |
Antitumor and antimetastatic activities of rhamnogalacturonan-II-type polysaccharide isolated from mature leaves of green tea via activation of macrophages and natural killer cells.
Topics: Animals; Antineoplastic Agents; Female; Glycosylation; Killer Cells, Natural; Lung Neoplasms; Macrophage Activation; Melanoma, Experimental; Methylation; Mice; Neoplasm Metastasis; Pectins; Plant Leaves; Polygalacturonase; Tea | 2017 |
Colon cancer: it's CIN or CIMP.
Topics: Chromosomal Instability; Colonic Neoplasms; CpG Islands; Disease Progression; DNA Methylation; Epigenesis, Genetic; Humans; Loss of Heterozygosity; Methylation; Microsatellite Repeats; Models, Biological; Models, Genetic; Neoplasm Metastasis; Phenotype; Prognosis | 2008 |
Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus.
Topics: Acetylation; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Differentiation; Esophageal Neoplasms; Esophagectomy; Female; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lymphatic Metastasis; Lysine; Male; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Protein Processing, Post-Translational; Retrospective Studies; Time Factors; Treatment Outcome | 2009 |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors | 2008 |
Anti-angiogenic and anti-metastatic effects of beta-1,3-D-glucan purified from Hanabiratake, Sparassis crispa.
Topics: Agaricales; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; beta-Glucans; Capillaries; Cell Line; Cell Movement; Cell Proliferation; Female; Humans; Lung Neoplasms; Melanoma, Experimental; Methylation; Mice; Mice, Inbred ICR; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Proteoglycans; Structure-Activity Relationship; Vascular Endothelial Growth Factor A | 2009 |
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Assembly and Disassembly; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Genome, Human; Histones; Humans; Methylation; Mice; Mice, Nude; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Polycomb-Group Proteins; Prognosis; Repressor Proteins; RNA Interference; RNA, Untranslated; Survival Rate | 2010 |
Post-treatment circulating plasma BMP6 mRNA and H3K27 methylation levels discriminate metastatic prostate cancer from localized disease.
Topics: Aged; Biomarkers; Bone Morphogenetic Protein 6; Diagnosis, Differential; Histones; Humans; Male; Methylation; Neoplasm Metastasis; Neoplasm Staging; Prostatic Neoplasms; RNA, Messenger | 2010 |
Re: Post-treatment circulating plasma BMP6 mRNA and H3K27 methylation levels discriminate metastatic prostate cancer from localized disease.
Topics: Bone Morphogenetic Protein 6; Diagnosis, Differential; Histones; Humans; Male; Methylation; Neoplasm Metastasis; Prostatic Neoplasms; RNA, Messenger | 2010 |
Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.
Topics: Animals; Cell Line, Tumor; Cytoskeletal Proteins; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Methylation; Mice; Neoplasm Metastasis; Promoter Regions, Genetic; Rhabdomyosarcoma | 2010 |
Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1.
Topics: Collagen Type XI; Computational Biology; Fibroblasts; Humans; Inhibin-beta Subunits; Methylation; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Thrombospondins; Treatment Outcome | 2010 |
FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells.
Topics: Acetylation; Animals; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Chromatin Immunoprecipitation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins; Repressor Proteins; RNA Interference; RNA, Small Interfering; Transcription Factors; Transfection | 2012 |
H3K27me3 protein is a promising predictive biomarker of patients' survival and chemoradioresistance in human nasopharyngeal carcinoma.
Topics: Biomarkers, Tumor; Blotting, Western; Carcinoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Histones; Humans; Immunohistochemistry; Lysine; Male; Methylation; Middle Aged; Models, Biological; Multivariate Analysis; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Predictive Value of Tests; Prognosis; Radiation Tolerance; ROC Curve; Survival Analysis; Treatment Outcome | 2011 |
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease-Free Survival; Down-Regulation; Esophageal Neoplasms; Humans; Methylation; Mice; Mice, SCID; MicroRNAs; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Prognosis; Real-Time Polymerase Chain Reaction; Receptor, IGF Type 1; Survival Analysis | 2012 |
Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Chemokines, CC; Chick Embryo; Chromatin Assembly and Disassembly; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Multiprotein Complexes; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Nuclear Proteins; Protein Interaction Mapping; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Repressor Proteins; RNA, Small Interfering | 2011 |
Global histone H3K27 methylation levels are different in localized and metastatic prostate cancer.
Topics: Histones; Humans; Male; Methylation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prostatic Neoplasms | 2012 |
An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer.
Topics: Analysis of Variance; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Epigenomics; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Protein Tyrosine Phosphatases; RNA Interference; RNA, Small Interfering; Signal Transduction; Statistics, Nonparametric | 2013 |
The regulatory mechanism of the LY6K gene expression in human breast cancer cells.
Topics: Antigens, Ly; Binding Sites; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factor AP-1 | 2012 |
Hypermethylation and aberrant expression of Wnt antagonist secreted frizzled-related protein 1 in gastric cancer.
Topics: Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Methylation; Methyltransferases; Neoplasm Metastasis; Neoplasm Staging; RNA, Messenger; Stomach Neoplasms; Wnt Proteins | 2007 |
Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis.
Topics: Animals; Coculture Techniques; Epigenesis, Genetic; Humans; Lung Neoplasms; Male; Methylation; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Prostatic Neoplasms; RNA, Small Interfering; Urokinase-Type Plasminogen Activator | 2007 |
JMJD3 is a histone H3K27 demethylase.
Topics: Binding Sites; Blotting, Western; Databases, Factual; DNA-Binding Proteins; Glutathione Transferase; HeLa Cells; Histones; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mutation; Neoplasm Metastasis; Oxidoreductases, N-Demethylating; Prostatic Neoplasms; Recombinant Fusion Proteins; Transfection | 2007 |
Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
Topics: Acetylcysteine; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antioxidants; Astrocytes; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endothelial Cells; Endothelium, Vascular; Formaldehyde; Histone Acetyltransferases; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Prodrugs; Semicarbazides; Structure-Activity Relationship; Tegafur; Transplantation, Heterologous; Umbilical Cord | 2008 |
Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; DNA, Neoplasm; Methylation; Mice; Neoplasm Metastasis; Neoplasms, Experimental | 1984 |
Transcriptional regulation of the mts1 gene in human lymphoma cells: the role of DNA-methylation.
Topics: Azacitidine; Decitabine; DNA Modification Methylases; Gene Expression Regulation; Humans; Lymphoma; Methylation; Neoplasm Metastasis; Restriction Mapping; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Genes, chromosomes and cancer. First meeting of the "Arbeitsgemeinschaft Molekular- und Zytogenetik (AEK)" of the Deutsche Krebsgesellschaft.
Topics: Animals; Chromosome Aberrations; Humans; Methylation; Neoplasm Metastasis; Neoplasms; Oncogenes; Recombination, Genetic; Virus Integration | 1993 |
Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma.
Topics: Base Sequence; Carcinoma, Squamous Cell; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Esophageal Neoplasms; Gene Deletion; Gene Expression Regulation, Neoplastic; Homozygote; Humans; Lymphatic Metastasis; Methylation; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Staging; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational | 1996 |
Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Chi-Square Distribution; Colorectal Neoplasms; Decitabine; Female; Humans; Immunohistochemistry; In Situ Hybridization; Intestinal Mucosa; Lymphatic Metastasis; Male; Membrane Glycoproteins; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Proteoglycans; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Syndecan-1; Syndecans; Tumor Cells, Cultured | 2001 |
Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences.
Topics: Animals; Base Sequence; Humans; Kidney Neoplasms; Methylation; Mice; Molecular Sequence Data; Neoplasm Metastasis; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; Transcription, Genetic; Tumor Cells, Cultured; Wilms Tumor | 1992 |
[Characteristics of a positive regulatory element in the first intron of the mts1 gene].
Topics: Animals; Base Sequence; CD3 Complex; Chloramphenicol O-Acetyltransferase; DNA; Enhancer Elements, Genetic; Introns; Methylation; Mice; Molecular Sequence Data; Neoplasm Metastasis; Nuclear Proteins; Plasmids; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Patterns of methylation of the c-myc gene in human colorectal cancer progression.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Base Sequence; Cell Division; Colon; Colonic Polyps; Colorectal Neoplasms; DNA, Neoplasm; Epithelium; Exons; Female; Genes, myc; Humans; Hyperplasia; Male; Methylation; Middle Aged; Neoplasm Metastasis | 1992 |
Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas.
Topics: Adult; Aged; Blotting, Southern; Breast Neoplasms; DNA; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Methylation; Middle Aged; Neoplasm Metastasis; Nuclear Proteins; Proto-Oncogene Proteins; Receptor, ErbB-2; Restriction Mapping; Uterine Cervical Neoplasms | 1991 |
Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine.
Topics: Animals; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Decitabine; DNA; Genes, ras; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylation; Mice; Mice, Nude; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger | 1991 |
Effects of methylthiodeoxyadenosine and its analogs on in vitro invasion of rat ascites hepatoma cells and methylation of their phospholipids.
Topics: Animals; Cell Division; Cell Membrane; Deoxyadenosines; In Vitro Techniques; Liver Neoplasms, Experimental; Membrane Fluidity; Membrane Lipids; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Phospholipids; Thionucleosides; Thionucleotides; Tumor Cells, Cultured | 1991 |
Effect of 5-azacytidine on DNA methylation and the malignant properties of B16 melanoma cells.
Topics: Animals; Azacitidine; Deoxycytidine; DNA, Neoplasm; Female; Lung Neoplasms; Melanoma; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis | 1985 |
Enhanced experimental metastatic capacity of a human tumor line following treatment with 5-azacytidine.
Topics: Animals; Azacitidine; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Killer Cells, Natural; Lung Neoplasms; Melanoma; Methylation; Mice; Neoplasm Metastasis; Neoplasm Transplantation | 1986 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis | 1986 |
Changes in the tumorigenic and metastatic properties of tumor cells treated with quercetin or 5-azacytidine.
Topics: Animals; Azacitidine; Cell Line; DNA; Fibrosarcoma; Flavonoids; Methylation; Mice; Mice, Inbred C57BL; Mutagens; Neoplasm Metastasis; Neoplasm Transplantation; Phenotype; Quercetin | 1987 |
The c-fos proto-oncogene in murine 3LL carcinoma clones controls the expression of MHC genes.
Topics: Actins; Animals; Carcinoma; Gene Expression Regulation; Genes, MHC Class I; H-2 Antigens; Interferons; Methylation; Mice; Neoplasm Metastasis; Proto-Oncogene Proteins; Proto-Oncogenes; Transcription, Genetic | 1988 |
[Study of transcription of the DNA sequence of a mts271 clone in various tumor and normal mouse cells].
Topics: Animals; Cells, Cultured; Clone Cells; DNA; DNA, Neoplasm; Gene Expression; Methylation; Mice; Neoplasm Metastasis; Nucleic Acid Hybridization; RNA; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Biology of metastasis.
Topics: Animals; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Methylation; Mutation; Neoplasm Metastasis; Phenotype | 1986 |
Genetic and epigenetic aspects of tumor progression and tumor heterogeneity.
Topics: Animals; Cell Line; DNA; Humans; Methylation; Neoplasm Metastasis; Neoplasms; Oncogenes | 1985 |
Analysis of intact gangliosides by mass spectrometry. Comparison of different derivatives of a hematoside of a tumour and the major monosialoganglioside of brain.
Topics: Aluminum; Brain; Brain Neoplasms; Carcinoma; Ceramides; Fatty Acids; Gangliosides; Humans; Kidney Neoplasms; Lithium; Mass Spectrometry; Methylation; Molecular Weight; Neoplasm Metastasis; Neuraminic Acids; Oxidation-Reduction; Silicon Dioxide; Temperature | 1974 |
Cytolipin R and its possible precursor ceramide trisaccharide from metastatic rat mammary tumor.
Topics: Animals; Antigens, Neoplasm; Ceramides; Cerebrosides; Chromatography, Thin Layer; Fatty Acids; Female; Glycolipids; Hydrolysis; Lung; Mammary Neoplasms, Experimental; Methylation; Methylcholanthrene; Molecular Conformation; Neoplasm Metastasis; Neoplasm Transplantation; Oxidation-Reduction; Periodic Acid; Polysaccharides; Rats; Transplantation, Homologous | 1974 |
Transfer RNA methylase and transfer RNA methylase-inhibitor activity in normal and malignant human ovarian tissue.
Topics: Animals; Carbon Radioisotopes; Female; Guanine; Humans; Methylation; Neoplasm Metastasis; Ovarian Neoplasms; Ovary; Rabbits; RNA, Transfer; tRNA Methyltransferases | 1973 |
Induction of malignant lymphomas by N,N'-dimethylnitrosourea in adult mice.
Topics: Animals; Carcinogens; Female; Lymphatic Metastasis; Lymphoma; Male; Methylation; Methylnitrosourea; Mice; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Thymus Neoplasms; Urea | 1971 |
Studies of combination 6-mercaptopurine (NSC-755) and 6-methylmercaptopurine riboside (NSC-40774) in patients with acute leukemia and metastatic cancer.
Topics: Acute Disease; Adult; Aged; Female; Humans; Leukemia; Male; Mercaptopurine; Methylation; Middle Aged; Neoplasm Metastasis; Ribose | 1968 |
Pulmonary and hepatic oncogenesis during treatment of male RF mice with dimethyl-nitrosamine.
Topics: Adenoma; Animals; Hemangioendothelioma; Hemangiosarcoma; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasm Metastasis; Nitrosamines; Rats; Time Factors | 1968 |