isomethyleugenol has been researched along with Malignant Melanoma in 81 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (25.93) | 18.7374 |
1990's | 7 (8.64) | 18.2507 |
2000's | 9 (11.11) | 29.6817 |
2010's | 27 (33.33) | 24.3611 |
2020's | 17 (20.99) | 2.80 |
Authors | Studies |
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Boers, J; Boers, R; Brands, T; de Klein, A; Gribnau, J; Kilic, E; Mensink, H; Smit, KN; Vaarwater, J; van IJcken, WFJ; Verdijk, RM | 1 |
Bankfalvi, A; Griewank, K; Hadaschik, E; Horn, S; Jansen, P; Kretz, J; Kutzner, H; Livingstone, E; Lutsik, P; Mayakonda, A; Möller, I; Müller, H; Murali, R; Paschen, A; Philip, M; Plass, C; Riedel, A; Rose, C; Schadendorf, D; Schaller, J; Stadtler, N; Sucker, A; Zaremba, A; Zimmer, L | 1 |
Bao, Z; Cong, P; Hou, H; Wei, W; Yu, X; Zhou, Y | 1 |
Chen, J; Chen, R; Garza, LA; Hu, Z; Kang, S; Liao, W; Miao, Y; Sweren, E; Wang, G; Wang, J; Zeng, D | 1 |
Hu, J; Jia, Q; Li, H; Li, T; Wang, C; Zhang, J; Zhang, X; Zhong, L | 1 |
Chai, P; Fan, X; Ge, S; Ge, T; Gu, X; Jia, R; Wang, S; Zhuang, A | 1 |
Abbott, KL; Bosenberg, M; Burns, MJ; Chen, D; Esparza Moltó, PB; Farsakoglu, Y; Hargreaves, DC; Hoffmann, FA; Johnson, MA; Kaech, SM; Kunchok, T; Mangalhara, KC; Mendiratta, G; Parisi, B; Rincon, M; Rojas, GR; Sainz, AG; Shadel, GS; Tadepalle, N; Vander Heiden, MG; Varanasi, SK | 1 |
Chai, P; Fan, X; Ge, S; Jia, R; Sun, B; Wang, S; Xu, Y; Yang, Y; Yang, YG | 1 |
Chen, X; Dong, F; Hu, DN; Jin, S; Liu, Q; Luo, G; Reinach, PS; Wang, J; Wang, S; Xu, W; Yan, D; Zhao, Y | 1 |
Franco, R; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Zoumpourlis, V | 1 |
Doan, LT; Fruman, DA; Hanse, EA; Ishak Gabra, MB; Kong, M; Li, H; Lowman, XH; Schones, DE; Senapati, P; Tran, TQ; Xu, X; Yang, Y; Zhang, L | 1 |
Lu, J; Tang, J; Wan, Q | 1 |
Bleha, R; Capek, P; Čopíková, J; Kaštánek, P; Lukáč, P; Pohl, R; Rajsiglová, L; Sushytskyi, L; Synytsya, A; Vannucci, L | 1 |
Chai, P; Gu, X; He, F; Jia, R; Shi, H; Wang, S; Xu, X; Yang, J; Yu, J; Zhuang, A | 1 |
Anestopoulos, I; Cheung, W; Franco, R; Kyriakou, S; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Tetard, D; Trafalis, DT; Veuger, S | 1 |
Anestopoulos, I; Franco, R; Kyriakou, S; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT | 1 |
Han, P; Liao, Y; Ni, B; Zhang, Y | 1 |
DeBerardinis, RJ; Hu, Z; Huang, F; Morrison, SJ; Shi, X; Tasdogan, A | 1 |
Dhawan, D; Dörken, B; Elkahloun, A; Holmen, SL; Ji, S; Kemper, K; Lee, S; Li, L; Lohneis, P; Mallette, FA; Meierjohann, S; Peeper, DS; Qutob, N; Reimann, M; Samuels, Y; Schleich, K; Schmitt, CA; Silvis, MR; Speck, C; Treitschke, S; van Rooijen, E; Werner-Klein, M; Yu, Y; Yue, B; Zon, LI | 1 |
Choi, HS; Kim, G; Kim, JY; Kim, O; Lee, KY; Lim, SC | 1 |
Bootz, F; Dietrich, D; Dietrich, J; Gevensleben, H; Golletz, C; Goltz, D; Kristiansen, G; Landsberg, J; Vogt, TJ | 1 |
van Doorn, R | 1 |
Botaitis, S; Franco, R; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Vasantha Rupasinghe, HP; Zoumpourlis, V | 1 |
Cabezas-Herrera, J; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L | 1 |
Lewis, BC; Miners, JO | 1 |
Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y | 1 |
Agliano, F; Biondo, C; Morabito, S; Oteri, R; Teti, D; Venza, I; Venza, M; Visalli, M | 1 |
Kampilafkos, P; Kefalopoulou, Z; Lakoumentas, J; Melachrinou, M; Sotiropoulou-Bonikou, G | 1 |
Jin, SG; Pfeifer, GP; Wu, X; Xiong, W; Yang, L | 1 |
Choi, C; Hong, BJ; Kim, MY; Lee, J; Park, WY | 1 |
Basu, A; Dasari, V; Khosla, S; Mishra, RK; Tomar, A | 1 |
Fan, R; Gao, W; Guo, Y; Mu, S; Qin, G; Sun, Y; Wang, B; Wang, G; Wu, H; Xu, Z; Zhang, Z | 1 |
Lissanu Deribe, Y | 1 |
Bradner, JE; Burd, CE; Clark, KS; Fedoriw, Y; Jeck, WR; Liu, JY; Parker, JS; Paulk, J; Qi, J; Sharpless, NE; Simon, JM; Souroullas, GP; Xiong, J | 1 |
Ding, X; Fan, X; Ge, S; Jia, R; Li, J; Lin, M; Wang, X; Xing, Y; Zhang, H | 1 |
Busam, KJ; Gerami, P; Jungbluth, AA; Kinsler, V; Shah, KN; Sitzman, T | 1 |
Chen, J; Jia, Q; Luo, J; Seong, J; Singh, R; Sun, J; Tajik, A; Tan, Y; Wang, N; Wood, AR; Yang, F; Zhou, W | 1 |
Rodríguez-López, JN; Sánchez-del-Campo, L | 1 |
Boeckmann, L; Emmert, S; Gutzmer, R; Has, C; Kunz, M; Kuschal, C; Laspe, P; Struever, D; Thoms, KM | 1 |
Jarmalavicius, S; Trefzer, U; Walden, P | 1 |
Fukushima, T; Katayama, Y; Nagase, H; Ohta, T; Shinojima, Y; Terui, T; Watanabe, T; Yachi, K; Yoshino, A | 1 |
Lee, C; Lee, HS | 1 |
Lehner, B; Schuster-Böckler, B | 1 |
Borden, EC; Fruehauf, JP; Haney, R; Jacobs, BS; Lindner, DJ; Tuthill, R; Wu, Y | 1 |
Bosserhoff, AK; Hellerbrand, C; Limm, K; Mueller, DW; Oefner, P; Ott, C; Wallner, S | 1 |
Bazzoni, F; Brandau, S; Bruderek, K; Cassatella, MA; Castellucci, M; Natoli, G; Ostuni, R; Schilling, B; Tamassia, N; Zimmermann, M | 1 |
Demidem, A; Madelmont, JC; Morvan, D; Papon, J | 1 |
Behrmann, I; Bosserhoff, AK; Buettner, R; Heinrich, PC; Komyod, W; Schuierer, M; Wallner, S | 1 |
Baroni, A; D'Angelo, S; Donnarumma, G; Galletti, P; Ingrosso, D; Masella, L; Migliardi, V; Sorrentino, A; Tufano, MA; Zappia, M | 1 |
Bauer, UM; Behrmann, I; Haan, S; Heinrich, PC; Komyod, W | 1 |
Chang, CC; Ferrone, S; Lin, AF; Yan, WH | 1 |
Adachi, Y; Furihata, M; Ohtsuki, Y; Sonobe, H; Takeuchi, T | 1 |
Cheah, MS; Hoffman, RM; Wallace, CD | 1 |
Kobata, A; Mishima, Y; Ohkura, T; Yamashita, K | 1 |
Boon, MH; Parsons, PG | 1 |
Hayward, IP; Parsons, PG | 1 |
Gerard, GF; Green, M; Loewenstein, PM | 1 |
Bynum, JW | 1 |
Karhunen, T; Pavel, S; Slingerland, R; Smit, N; Tilgmann, C; Ulmanen, I; Westerhof, W | 1 |
Miwa, W; Sekine, T; Sekiya, T; Yashima, K | 1 |
Boon, T; Brasseur, F; De Backer, O; De Smet, C; Faraoni, I; Lurquin, C | 1 |
Berg, K; Fodstad, O; Goodchild, J; Hogset, A; Hovig, E; Maelandsmo, G; Perkins, T; Prasmickaite, L | 1 |
Bosserhoff, AK; Buettner, R; de Herreros, AG; Domínguez, D; Poser, I; Varnai, A | 1 |
Asberry, BE; Coleman, RE; Fair, WR; Primeau, JL; Straatmann, MG; Ter-Pogossian, MM; Welch, MJ | 1 |
Abbruzzese, JL; Frost, P | 1 |
Grant, JH; Kudlow, JE; Meluch, AA; Paterson, AJ; Shin, TH | 1 |
Dell, A; Khoo, KH; Manzi, AE; Sjoberg, ER; Varki, A | 1 |
Greig, R; Kline, T; Mallon, F; Poste, G; Trainer, DL | 1 |
Everett, CA; Hart, IR; Ormerod, EJ | 1 |
Everett, CA; Finch, M; Hart, IR; Ormerod, EJ | 1 |
Barbieri, R; Fisher, PB; Gambari, R; Giacomini, P; Natali, PG; Piva, R; Tecce, R | 1 |
Meese, E; Meltzer, PS; Trent, JM; Witkowski, CM | 1 |
Cerny, T; Margison, GP; Maynard, K; Parsons, PG | 1 |
Guirguis, RA; Liotta, LA; Schiffmann, E | 1 |
Einarsson, M; Kenne, L; Nilsson, B; Pohl, G | 1 |
Liteplo, RG; Munro, S | 1 |
Barbieri, R; Buzzoni, D; Gambari, R; Piva, R; Volinia, S | 1 |
Cassio, D; Sellem, CH; Weiss, MC | 1 |
Boehm, TL; Brzoska, MJ; Drahovsky, D; Werle, A | 1 |
Sasai, Y; Tanahashi, Y | 1 |
Kappler, JW | 1 |
3 review(s) available for isomethyleugenol and Malignant Melanoma
Article | Year |
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Physio-pathological effects of m6A modification and its potential contribution to melanoma.
Topics: Adenosine; Gene Expression; Humans; Melanoma; Methylation; Methyltransferases; Mutation; Oxidoreductases, N-Demethylating; Proto-Oncogene Proteins B-raf; RNA Processing, Post-Transcriptional; RNA Splicing Factors; RNA, Messenger; Skin Neoplasms | 2021 |
Generation, validation, and application of a P450 homology model.
Topics: Antineoplastic Agents; Biocatalysis; Cytochrome P-450 CYP1A1; Dacarbazine; Humans; Kinetics; Melanoma; Methylation; Models, Molecular; Mutation; Prodrugs; Reproducibility of Results; Structure-Activity Relationship | 2013 |
Tumor autocrine motility factor.
Topics: Cell Line; Cell Movement; Glucose-6-Phosphate Isomerase; Humans; Melanoma; Membrane Proteins; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Oncogenes | 1986 |
78 other study(ies) available for isomethyleugenol and Malignant Melanoma
Article | Year |
---|---|
Genome-wide aberrant methylation in primary metastatic UM and their matched metastases.
Topics: DNA Mutational Analysis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Methylation; Neoplasm Metastasis; Phosphoproteins; RNA Splicing Factors; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Uveal Neoplasms | 2022 |
Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors.
Topics: Diagnosis, Differential; DNA Copy Number Variations; Humans; Melanoma; Methylation; Nevus, Epithelioid and Spindle Cell; Paraganglioma; Skin Neoplasms; Syndrome | 2022 |
Construction of Prognostic Risk Model of Patients with Skin Cutaneous Melanoma Based on TCGA-SKCM Methylation Cohort.
Topics: Humans; Melanoma; Melanoma, Cutaneous Malignant; Methylation; Prognosis; Reproducibility of Results; Skin Neoplasms | 2022 |
N6-methyladenosine RNA Methylation Correlates with Immune Microenvironment and Immunotherapy Response of Melanoma.
Topics: Adenosine; Humans; Immunotherapy; Melanoma; Methylation; RNA; Tumor Microenvironment | 2023 |
Development and validation of an m6A RNA methylation regulator-based signature for the prediction of prognosis and immunotherapy in cutaneous melanoma.
Topics: Biomarkers, Tumor; Humans; Immunotherapy; Melanoma; Melanoma, Cutaneous Malignant; Methylation; Prognosis; RNA; Skin Neoplasms | 2023 |
Targeting histone deacetylase suppresses tumor growth through eliciting METTL14-modified m
Topics: Carcinogenesis; Cell Line, Tumor; Histone Deacetylases; Histones; Humans; Melanoma; Methylation; Methyltransferases; RNA; RNA-Binding Proteins | 2023 |
Manipulating mitochondrial electron flow enhances tumor immunogenicity.
Topics: Antigen Presentation; Antigens, Neoplasm; Cell Line, Tumor; Electron Transport Complex I; Electron Transport Complex II; Electrons; Gene Knockout Techniques; Histones; HSP40 Heat-Shock Proteins; Humans; Melanoma; Methylation; Mitochondria; Neoplasms | 2023 |
m
Topics: Adenosine; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Eye Neoplasms; Gene Expression Profiling; Humans; Melanoma; Methylation; Mitochondrial Proteins; Prognosis; RNA Processing, Post-Transcriptional; RNA, Messenger | 2019 |
RNA m
Topics: Adenosine; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epigenesis, Genetic; Gene Knockdown Techniques; Humans; Melanoma; Methylation; Methyltransferases; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; RNA, Messenger; RNA, Neoplasm; Up-Regulation; Uveal Neoplasms | 2020 |
Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma.
Topics: Acetylation; Animals; Cell Line, Tumor; Epigenesis, Genetic; Histone Acetyltransferases; Histones; Humans; Isothiocyanates; Melanoma; Methylation; Mice; Sulfoxides | 2021 |
Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Epigenesis, Genetic; Glutamine; Histones; Humans; Lysine; Male; Melanoma; Methylation; Mice, Nude; Signal Transduction; Transcriptome; Xenograft Model Antitumor Assays | 2020 |
The prognostic values of m6A RNA methylation regulators in uveal melanoma.
Topics: Biomarkers, Tumor; Datasets as Topic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Melanoma; Methylation; Middle Aged; Prognosis; RNA; Sequence Analysis, RNA; Survival Analysis; Transcriptome; Uveal Neoplasms | 2020 |
Immunoactive polysaccharides produced by heterotrophic mutant of green microalga Parachlorella kessleri HY1 (Chlorellaceae).
Topics: Animals; Antigens, CD; B-Lymphocytes; Carbohydrate Sequence; Chlorophyta; Gene Expression Regulation; Immunologic Factors; Interferon-gamma; Interleukin-2; Interleukin-4; Lipopolysaccharides; Melanoma; Methylation; Mice; Mice, Inbred C57BL; Molecular Weight; Plant Extracts; Polysaccharides; Primary Cell Culture; Skin Neoplasms; Solubility; T-Lymphocytes; Tumor Necrosis Factor-alpha; Water; Xylose | 2020 |
m
Topics: Adenosine; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Calcium; Cell Line, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Melanoma; Methylation; RNA; RNA Interference; Uveal Neoplasms | 2021 |
A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Ceramides; Flow Cytometry; Humans; Melanoma; Membrane Potential, Mitochondrial; Methylation; Mice; Mimosine; Oxidative Stress; Reactive Oxygen Species; Skin Neoplasms | 2021 |
Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma.
Topics: Acetylation; Cell Line, Tumor; Cell Survival; Epigenesis, Genetic; Histones; Humans; Isothiocyanates; Melanoma; Methylation; Skin Neoplasms | 2021 |
The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.
Topics: Animals; Cell Movement; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Histone-Lysine N-Methyltransferase; Histones; Humans; Indoles; Melanoma; Metabolome; Metabolomics; Methylation; Mice; Mice, Inbred NOD; Neoplasm Metastasis; Principal Component Analysis; Protein Methyltransferases; Proto-Oncogene Proteins B-raf; Pyridones; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous | 2017 |
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
Topics: Animals; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Melanoma; Methylation; Mice, Nude; Promoter Regions, Genetic | 2018 |
SUV39H1/DNMT3A-dependent methylation of the RB1 promoter stimulates PIN1 expression and melanoma development.
Topics: Animals; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Melanoma; Methylation; Methyltransferases; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Repressor Proteins; Retinoblastoma Protein | 2018 |
CTLA4 methylation predicts response to anti-PD-1 and anti-CTLA-4 immunotherapy in melanoma patients.
Topics: CTLA-4 Antigen; Epigenomics; Humans; Immunotherapy; Kaplan-Meier Estimate; Melanoma; Melanoma, Cutaneous Malignant; Methylation; Programmed Cell Death 1 Receptor; RNA, Messenger; Skin Neoplasms | 2018 |
Methylation marks melanoma metastasis.
Topics: Humans; Melanoma; Methylation; Skin Neoplasms | 2018 |
Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.
Topics: Acetylation; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Humans; Isothiocyanates; Lysine; Melanoma; Methylation; Mice | 2020 |
Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Female; Gene Silencing; Humans; Melanoma; Methotrexate; Methylation; Mice; Myosin Heavy Chains; Myosin Type V; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays | 2013 |
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.
Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors | 2014 |
Epigenetic marks responsible for cadmium-induced melanoma cell overgrowth.
Topics: Cadmium Chloride; Caspase 8; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Epigenesis, Genetic; Humans; Melanoma; Methylation; Real-Time Polymerase Chain Reaction; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Skin Neoplasms; Tumor Suppressor Protein p14ARF; Uveal Neoplasms | 2015 |
Epigenetic modifications in cutaneous malignant melanoma: EZH2, H3K4me2, and H3K27me3 immunohistochemical expression is enhanced at the invasion front of the tumor.
Topics: Adult; Aged; Biomarkers, Tumor; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Histones; Humans; Immunohistochemistry; Male; Melanoma; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplastic Stem Cells; Polycomb Repressive Complex 2; Predictive Value of Tests; Prognosis; Retrospective Studies; Skin Neoplasms | 2015 |
The DNA methylation landscape of human melanoma.
Topics: Cell Differentiation; DNA Methylation; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Histones; Humans; Immunity; Lysine; Melanocytes; Melanoma; Methylation; Transcription Initiation Site | 2015 |
H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis.
Topics: Animals; Cell Line, Tumor; Heterografts; Humans; Jumonji Domain-Containing Histone Demethylases; Melanoma; Melanoma, Cutaneous Malignant; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; NF-kappa B; Signal Transduction; Skin Neoplasms; Tumor Microenvironment | 2016 |
DNMT3L enables accumulation and inheritance of epimutations in transgenic Drosophila.
Topics: Animals; Animals, Genetically Modified; Chromatin Immunoprecipitation; DNA (Cytosine-5-)-Methyltransferases; Drosophila melanogaster; Epigenesis, Genetic; Eye; Genes, Insect; Histones; Inheritance Patterns; Larva; Melanoma; Methylation; Multigene Family; Oligonucleotide Array Sequence Analysis; Organ Specificity; Phenotype; Promoter Regions, Genetic; Transcription, Genetic; Wings, Animal | 2016 |
NF-YA promotes invasion and angiogenesis by upregulating EZH2-STAT3 signaling in human melanoma cells.
Topics: CCAAT-Binding Factor; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Melanoma; Methylation; Neoplasm Invasiveness; Neovascularization, Pathologic; Signal Transduction; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2016 |
Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma.
Topics: Animals; Cell Line, Tumor; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Histones; Humans; Melanoma; Membrane Proteins; Methylation; Mice; Mutation; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase | 2016 |
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Topics: Animals; B-Lymphocytes; Carcinogenesis; Cell Line, Tumor; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Code; Humans; Immunoblotting; Lymphoma, B-Cell; Melanocytes; Melanoma; Methylation; Mice; Monomeric GTP-Binding Proteins; Mutation; Neoplasm Transplantation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2016 |
PAUPAR lncRNA suppresses tumourigenesis by H3K4 demethylation in uveal melanoma.
Topics: Animals; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histones; Humans; Male; Melanoma; Methylation; Mice; Mice, Nude; Neoplasm Proteins; RNA, Long Noncoding; RNA, Neoplasm; Transcription Factor HES-1; Uveal Neoplasms | 2016 |
Reduced H3K27me3 Expression Is Common in Nodular Melanomas of Childhood Associated With Congenital Melanocytic Nevi But Not in Proliferative Nodules.
Topics: Biomarkers, Tumor; Cell Proliferation; Child; Child, Preschool; Diagnosis, Differential; Epigenesis, Genetic; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; Infant; Infant, Newborn; Male; Melanoma; Methylation; Nevus, Pigmented; Skin Neoplasms | 2017 |
Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells.
Topics: Animals; cdc42 GTP-Binding Protein; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Focal Adhesion Kinase 1; Histones; Humans; Lysine; Melanoma; Methylation; Mice; rhoA GTP-Binding Protein; SOXB1 Transcription Factors; Tumor Stem Cell Assay | 2017 |
Targeting the methionine cycle for melanoma therapy with 3-O-(3,4,5-trimethoxybenzoyl)-(-)-epicatechin.
Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Blotting, Western; Caspase 3; Catechin; Cell Line, Tumor; DNA Primers; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Melanoma; Methionine; Methylation; Mice; Microscopy, Confocal; Microscopy, Electron; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Modulation of the efficacy of temozolomide and dacarbazine melanoma treatment by DNA-repair factors in vivo and in vitro.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Clinical Trials as Topic; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lymphocytes; Melanoma; Methylation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Prodrugs; Promoter Regions, Genetic; RNA, Messenger; Temozolomide; Tumor Suppressor Proteins | 2009 |
Differential arginine methylation of the G-protein pathway suppressor GPS-2 recognized by tumor-specific T cells in melanoma.
Topics: Arginine; Cell Line, Tumor; Cells, Cultured; Chromatography, High Pressure Liquid; HLA-A Antigens; HLA-A11 Antigen; Humans; Intracellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Mass Spectrometry; Melanoma; Methylation; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; T-Lymphocytes | 2010 |
Aberrant hypermethylation of non-promoter zygote arrest 1 (ZAR1) in human brain tumors.
Topics: Astrocytoma; Brain; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Egg Proteins; Glioblastoma; Glioma; Humans; Mass Spectrometry; Melanoma; Methylation; Nevus; Oligodendroglioma; Pituitary Neoplasms; Reference Values | 2010 |
Structural analysis of a new cytotoxic demethylated analogue of neo-N-methylsansalvamide with a different peptide sequence produced by Fusarium solani isolated from potato.
Topics: Amino Acid Sequence; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Depsipeptides; Female; Fusarium; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Methylation; Molecular Structure; Ovarian Neoplasms; Peptides, Cyclic; Solanum tuberosum; Spectrometry, Mass, Electrospray Ionization; Uterine Neoplasms | 2012 |
Chromatin organization is a major influence on regional mutation rates in human cancer cells.
Topics: Animals; CpG Islands; Epigenesis, Genetic; Euchromatin; Genome, Human; Heterochromatin; Histones; Humans; Leukemia; Lung Neoplasms; Male; Melanoma; Methylation; Mutagenesis; Mutation Rate; Neoplasms; Pan troglodytes; Polymorphism, Single Nucleotide; Principal Component Analysis; Prostatic Neoplasms; Small Cell Lung Carcinoma | 2012 |
Thrombospondin-1 expression in melanoma is blocked by methylation and targeted reversal by 5-Aza-deoxycytidine suppresses angiogenesis.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Decitabine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Methylation; Mice; Neovascularization, Pathologic; Promoter Regions, Genetic; Xenograft Model Antitumor Assays | 2013 |
Deregulation of protein methylation in melanoma.
Topics: Arginine; Cell Line, Tumor; Deoxyadenosines; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunohistochemistry; Melanoma; Methylation; Nuclear Proteins; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Purine-Nucleoside Phosphorylase; Reverse Transcriptase Polymerase Chain Reaction; Thionucleosides | 2013 |
Cutting edge: An inactive chromatin configuration at the IL-10 locus in human neutrophils.
Topics: Animals; Cells, Cultured; Chromatin; Chromatin Immunoprecipitation; Enhancer Elements, Genetic; Gene Expression Regulation; Genetic Loci; Histones; Humans; Interleukin-10; Melanoma; Methylation; Mice; Monocytes; Neutrophils; Protein Conformation; Protein Processing, Post-Translational; Skin Neoplasms; Species Specificity; Synteny | 2013 |
L-methionine supplementation accelerates tumour growth and shifts the phospholipid derivative pattern in a murine model of malignant melanoma. A proton HRMAS NMR spectroscopy study.
Topics: Animals; Cell Division; Dietary Supplements; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Melanoma; Methionine; Methylation; Mice; Mice, Inbred C57BL; Phospholipids | 2002 |
Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma.
Topics: Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Melanocytes; Melanoma; Methylation; Mutation; Nevus, Pigmented; Promoter Regions, Genetic; Purine-Nucleoside Phosphorylase; Tumor Cells, Cultured | 2003 |
Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells.
Topics: Antioxidants; Apoptosis; Humans; Isoaspartic Acid; Lipid Peroxidation; Melanoma; Methylation; Olive Oil; Oxidation-Reduction; Oxidative Stress; Phenylethyl Alcohol; Plant Oils; Proteins; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Ultraviolet Rays | 2005 |
Are STATS arginine-methylated?
Topics: Animals; Arginine; Blotting, Western; Cell Line, Tumor; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glutathione Transferase; Humans; Immunoprecipitation; Interferon-alpha; Interferons; Interleukin-6; Lysine; Melanoma; Methylation; Methyltransferases; Mice; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oncostatin M; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphatidylinositol 3-Kinases; Plasmids; Protein Structure, Tertiary; Receptors, Interleukin-6; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transfection; Tyrosine | 2005 |
Induction of HLA-G expression in a melanoma cell line OCM-1A following the treatment with 5-aza-2'-deoxycytidine.
Topics: Azacitidine; Calreticulin; Cell Line, Tumor; Choriocarcinoma; Decitabine; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Melanoma; Methylation; Promoter Regions, Genetic; Transcription, Genetic | 2005 |
A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.
Topics: Animals; Cell Line; Chlorocebus aethiops; CpG Islands; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Melanoma; Methylation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Neoplastic Stem Cells; Promoter Regions, Genetic; Proto-Oncogene Proteins c-met; RNA, Messenger; Snail Family Transcription Factors; Transcription Factor AP-2; Transcription Factors; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2006 |
Hypomethylation of DNA in human cancer cells: a site-specific change in the c-myc oncogene.
Topics: Base Sequence; Cell Line; DNA Restriction Enzymes; DNA, Neoplasm; Glioma; Humans; Lung Neoplasms; Melanoma; Methylation; Neoplasms; Oncogenes | 1984 |
Purification of hamster melanoma tyrosinases and structural studies of their asparagine-linked sugar chains.
Topics: Animals; Asparagine; Carbohydrate Sequence; Catechol Oxidase; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cricetinae; Electrophoresis, Polyacrylamide Gel; Melanoma; Mesocricetus; Methylation; Monophenol Monooxygenase; Oligosaccharides | 1984 |
Cyclophosphamide resistance developed in a human melanoma cell line.
Topics: Benzamides; Caffeine; Cell Line; Cross-Linking Reagents; Cyclophosphamide; Drug Resistance; Humans; Melanoma; Methylation; Microsomes, Liver | 1984 |
Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents.
Topics: Adenoviruses, Human; Alkylating Agents; Animals; Cattle; Cell Line; Cell Transformation, Viral; DNA; DNA, Neoplasm; Drug Resistance; Humans; Melanoma; Methylation; Phenotype; Thymus Gland | 1984 |
Characterization of a DNA polymerase activity in cultured human melanoma cells that copies poly(2'-O-methylcytidylate).
Topics: Cell Line; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; Humans; Kinetics; Lung Neoplasms; Melanoma; Methylation; Molecular Weight; Oligodeoxyribonucleotides; Poly C; Polyribonucleotides; Templates, Genetic | 1980 |
Characterization of adenosine-induced cytostasis in melanoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Count; Cell Division; Cell Line; Guanosine; Homocysteine; Melanoma; Methylation; Mice; Neoplasms, Experimental; Pyrimidines; RNA, Neoplasm; Uridine | 1980 |
O-methylation of L-dopa in melanin metabolism and the presence of catechol-O-methyltransferase in melanocytes.
Topics: 1-Methyl-3-isobutylxanthine; Catechol O-Methyltransferase; Cells, Cultured; Humans; Isoenzymes; Levodopa; Melanins; Melanocytes; Melanoma; Membrane Proteins; Methylation; Microscopy, Immunoelectron; Monophenol Monooxygenase; Neoplasm Proteins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Demethylation of a repetitive DNA sequence in human cancers.
Topics: Base Sequence; Blotting, Southern; Cloning, Molecular; Colonic Neoplasms; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Electrophoresis; Female; Genetic Techniques; Humans; Melanoma; Methylation; Molecular Sequence Data; Neoplasms; Pancreatic Neoplasms; Placenta; Pregnancy; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured | 1995 |
The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Base Sequence; Decitabine; Dinucleoside Phosphates; DNA; DNA Modification Methylases; DNA Primers; DNA Probes; DNA, Neoplasm; Enzyme Inhibitors; Genome, Human; Humans; Male; Melanoma; Melanoma-Specific Antigens; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; T-Lymphocytes, Cytotoxic; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis.
Topics: Base Sequence; Biological Transport; Electrophoresis, Capillary; Fatty Acids, Monounsaturated; Fluorescent Dyes; Humans; Kinetics; Melanoma; Methylation; Oligoribonucleotides; Quaternary Ammonium Compounds; RNA Caps; RNA, Catalytic; Transfection; Tumor Cells, Cultured | 1998 |
Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail.
Topics: Blotting, Western; Cadherins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Humans; Melanoma; Methylation; Oligonucleotides, Antisense; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Transcription Factor AP-2; Transcription Factors; Transfection; Tumor Cells, Cultured; Up-Regulation | 2001 |
Carbon-11-labeled methylated polyamine analogs: uptake in prostate and tumor in animal models.
Topics: Animals; Carbon Radioisotopes; Dogs; Male; Melanoma; Methylation; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Spermidine; Spermine; Tomography | 1977 |
Studies on the mechanism of the synergistic interaction between 2'-deoxy-5-azacytidine and cisplatin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cisplatin; Decitabine; DNA, Neoplasm; Drug Resistance; Drug Synergism; Humans; Melanoma; Methylation; Mice; Sensitivity and Specificity; Tubercidin; Tumor Cells, Cultured | 1992 |
5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor alpha expression.
Topics: Azacitidine; Base Sequence; DNA; Gene Expression Regulation; Humans; Kinetics; Melanoma; Methylation; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1992 |
Structural and immunological characterization of O-acetylated GD2. Evidence that GD2 is an acceptor for ganglioside O-acetyltransferase in human melanoma cells.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Clone Cells; Gangliosides; Gas Chromatography-Mass Spectrometry; Golgi Apparatus; Humans; Melanoma; Methylation; Molecular Sequence Data; Sialic Acids | 1992 |
Effect of 5-azacytidine on DNA methylation and the malignant properties of B16 melanoma cells.
Topics: Animals; Azacitidine; Deoxycytidine; DNA, Neoplasm; Female; Lung Neoplasms; Melanoma; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis | 1985 |
Enhanced experimental metastatic capacity of a human tumor line following treatment with 5-azacytidine.
Topics: Animals; Azacitidine; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Killer Cells, Natural; Lung Neoplasms; Melanoma; Methylation; Mice; Neoplasm Metastasis; Neoplasm Transplantation | 1986 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis | 1986 |
Regulation of the expression of class II genes of the human major histocompatibility complex in tumor cells.
Topics: Azacitidine; B-Lymphocytes; DNA, Neoplasm; Gene Expression Regulation; Genes, MHC Class II; HLA-D Antigens; HLA-DR Antigens; Humans; Interferons; Leukemia, Erythroblastic, Acute; Major Histocompatibility Complex; Melanoma; Methylation; Recombinant Proteins; Tumor Cells, Cultured | 1987 |
Molecular mapping of the oncogene MYB and rearrangements in malignant melanoma.
Topics: Blotting, Southern; Chromosomes, Human, Pair 6; DNA, Neoplasm; Electrophoresis, Agar Gel; Gene Rearrangement; Humans; Karyotyping; Melanoma; Methylation; Oncogenes; Restriction Mapping; Tumor Cells, Cultured | 1989 |
Relationships among cell survival, O6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adenovirus 5 and herpes simplex virus type 1 in human melanoma cell lines.
Topics: Adenoviruses, Human; Alkylating Agents; Cell Survival; Dacarbazine; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Humans; Melanoma; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Simplexvirus; Tumor Cells, Cultured | 1989 |
Isolation and characterization of three different carbohydrate chains from melanoma tissue plasminogen activator.
Topics: Amino Acids; Carbohydrate Conformation; Carbohydrate Sequence; Glycopeptides; Glycoproteins; Glycoside Hydrolases; Humans; Melanoma; Methylation; Molecular Sequence Data; Oligosaccharides; Tissue Plasminogen Activator | 1987 |
DNA methylating capacity in metastatic variants of a human melanoma cell line.
Topics: Cell Line; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Genetic Variation; Humans; Melanoma; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine | 1988 |
Clustering of undermethylated CCGG and GCGC sequences in the 5' region of the Ha-ras-1 oncogene of human leukemic K562 cells.
Topics: Base Sequence; Cell Line; Humans; Leukemia, Myeloid; Melanoma; Methylation; Nucleic Acid Hybridization; Oncogenes; Promoter Regions, Genetic | 1987 |
Activation of a silent gene is accompanied by its demethylation.
Topics: Animals; Cell Line; Chromosome Mapping; Gene Expression Regulation; Hybrid Cells; L Cells; Leukemia, Lymphoid; Liver Neoplasms, Experimental; Melanoma; Methylation; Mice; Nucleic Acid Hybridization; Rats; Serum Albumin; Transcriptional Activation | 1985 |
Suppression of malignant phenotype, changes in gene expression and DNA hypermethylation in human melanoma cells treated with arabinosyl cytosine.
Topics: Cell Line; Cytarabine; DNA, Neoplasm; Humans; Kinetics; Melanoma; Methylation; Oncogenes; Phenotype; Transcription, Genetic | 1985 |
Histochemical study of the alcianophilia of Paget cells in extramammary Paget's disease.
Topics: Biopsy; Cytoplasm; Deoxyribonucleases; Histocytochemistry; Humans; Hyaluronoglucosaminidase; Ions; Melanoma; Methylation; Neuraminidase; Nucleic Acids; Paget Disease, Extramammary; Ribonucleases; Skin; Skin Neoplasms; Staining and Labeling | 1969 |
The 5-methylcytosine content of DNA: tissue specificity.
Topics: Adrenal Gland Neoplasms; Animals; Carbon Isotopes; Cell Line; Chick Embryo; Clone Cells; Culture Techniques; Cytosine; DNA; DNA, Neoplasm; Male; Melanoma; Methods; Methylation; Mice; Neuroblastoma; Nucleosides; Pituitary Neoplasms; Teratoma; Testicular Neoplasms | 1971 |