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isomethyleugenol and Lupus Erythematosus, Systemic

isomethyleugenol has been researched along with Lupus Erythematosus, Systemic in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.51)18.7374
1990's5 (13.51)18.2507
2000's5 (13.51)29.6817
2010's15 (40.54)24.3611
2020's7 (18.92)2.80

Authors

AuthorsStudies
Chang, J; Cheng, C; Miao, C; Wang, X; Zhou, W1
Hou, S; Li, Y; Yang, B; Zhao, J1
Deng, LJ; Fan, YG; Leng, RX; Pan, HF; Wu, J; Xia, YR; Ye, DQ1
Chang, J; Cheng, C; Huang, Y; Miao, C; Wang, X; Wang, Y; Xu, S; Xue, Q1
Chen, W; Lin, J; Yang, F1
Anguera, MC; Buckner, JH; Cancro, MP; Knox, JJ; Paneru, B; Posso, S; Pyfrom, S1
Brinks, R; Chehab, G; Düsing, C; Gebhard, C; Raithel, J; Rehli, M; Richter, JG; Rosenbaum, A; Schneider, M; Sokolowski, A; Vordenbäumen, S1
Fu, S; Long, H; Lu, Q; Wu, H; Yin, H; Zhang, Q; Zhao, M1
Berr, S; Hünig, T; Langenhorst, D; Sawitzki, B; Tabares, P; Ten Berge, I; Tony, HP1
Berger, M; Hoebe, K; Kono, DH; Lawson, BR; Manenkova, Y; Tardif, V; Theofilopoulos, AN; Yuan, C; Zuo, JP1
Chang, HH; Fan-June, MC; Hsu, TC; Hu, HH; Lee, YJ; Li, C; Tsay, GJ; Wei, HM1
Gao, F; Gao, R; Guo, S; Liu, Y; Ma, Y; Shao, Y; Wu, F; Zhang, W; Zhao, Q; Zhu, L1
Golding, A; Hasni, S; Illei, G; Shevach, EM1
Chan, TM; Dai, Y; Li, D; Liang, G; Lu, Q; Tan, Y; Tang, Q; Wu, H; Xie, Y; Yang, Y; Yung, S; Zhao, M1
Leung, YT; Petri, MA; Shi, L; Song, L; Sullivan, KE; Zhang, Z1
Dawany, N; Kelsen, J; Petri, MA; Shi, L; Sullivan, KE; Zhang, Z1
Bayarsaihan, D1
Araki, Y; Mimura, T1
Gorelik, G; Jeffries, M; Johnson, K; Knowlton, N; Lu, Q; Osban, J; Ray, D; Richardson, B; Sawalha, AH; Webb, R1
Gao, F; Liang, Y; Lu, Q; Tang, J; Wu, X; Yin, H; Zhao, M1
Berden, JH; Dieker, JW; Kroeze, Y; Muller, S; Tamboer, WP; van Bavel, CC; van der Vlag, J; Voll, R1
Hedrich, CM; Kis-Toth, K; Kyttaris, VC; Rauen, T; Tsokos, GC1
Clarke, SG; Gee, AJ; Gee, RJ; Khare, S; Mamula, MJ; Yang, ML; Zurita-Lopez, CI1
Lin, WJ; Sun, KH; Tang, SJ; Wang, YS; You, RI1
David, M; Schurter, BT; Smith, WA; Wong-Staal, F1
Lu, Q; Ray, D; Richardson, B; Tesmer, L; Wu, A; Yousif, N1
Mi, XB; Zeng, FQ1
Okuhara, E1
Chrisp, CE; Johnson, KJ; Quddus, J; Richardson, BC; Yung, RL1
Richardson, BC; Yung, RL1
Huck, S; Zouali, M1
Corvetta, A; Della Bitta, R; Luchetti, MM; Pomponio, G1
Gross, L; Hanash, S; Johnson, M; Richardson, B; Scheinbart, L; Strahler, J1
Compton, LJ; Jackson, RA; Sano, H; Sasaki, T; Shiomi, N; Steinberg, AD1
Kanoh, T; Niwa, Y; Ozaki, Y; Sakane, T; Taniguchi, S1
Boyle, WJ; Evans, JL; Ting, JP1
Tan, EM1

Reviews

7 review(s) available for isomethyleugenol and Lupus Erythematosus, Systemic

ArticleYear
The molecular structure and biological functions of RNA methylation, with special emphasis on the roles of RNA methylation in autoimmune diseases.
    Critical reviews in clinical laboratory sciences, 2022, Volume: 59, Issue:3

    Topics: Humans; Lupus Erythematosus, Systemic; Methylation; Molecular Structure; RNA; RNA Processing, Post-Transcriptional

2022
M6A methylation modification in autoimmune diseases, a promising treatment strategy based on epigenetics.
    Arthritis research & therapy, 2023, 10-02, Volume: 25, Issue:1

    Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Epigenesis, Genetic; Humans; Lupus Erythematosus, Systemic; Methylation

2023
Post-translational modifications in T cells in systemic erythematosus lupus.
    Rheumatology (Oxford, England), 2021, 06-18, Volume: 60, Issue:6

    Topics: Acetylation; Antibodies, Monoclonal, Humanized; B-Cell Activating Factor; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Glycosylation; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lymphopenia; Methylation; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction; Sumoylation; Ubiquitination

2021
The Histone Modification Code in the Pathogenesis of Autoimmune Diseases.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Animals; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Autoimmunity; Catalysis; Chromatin; Diabetes Mellitus, Type 1; DNA; DNA Methylation; Epigenesis, Genetic; Genetic Predisposition to Disease; Histone Code; Histones; Humans; Inflammation; Lupus Erythematosus, Systemic; Methylation; Phenotype; Phosphorylation

2017
[Antigenicity and antigenic determinants of nucleic acids ].
    Ryumachi. [Rheumatism], 1982, Volume: 22, Issue:3

    Topics: Acetylation; Adjuvants, Immunologic; Animals; Antibody Formation; Antigens; Complement System Proteins; DNA; Epitopes; Humans; Immunoglobulins; Lupus Erythematosus, Systemic; Methylation; Poly A-U; RNA; RNA, Double-Stranded; RNA, Viral

1982
Role of T cell DNA methylation in lupus syndromes.
    Lupus, 1994, Volume: 3, Issue:6

    Topics: Azacitidine; DNA; Humans; Lupus Erythematosus, Systemic; Lymphocyte Function-Associated Antigen-1; Methylation; Procainamide; T-Lymphocytes

1994
DNA methylation: a potential pathway to abnormal autoreactive lupus B cells.
    Clinical immunology and immunopathology, 1996, Volume: 80, Issue:1

    Topics: Animals; Autoantibodies; B-Lymphocytes; DNA; Humans; Lupus Erythematosus, Systemic; Methylation

1996

Trials

1 trial(s) available for isomethyleugenol and Lupus Erythematosus, Systemic

ArticleYear
cAMP-responsive element modulator α (CREMα) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE).
    The Journal of biological chemistry, 2012, Feb-10, Volume: 287, Issue:7

    Topics: Acetylation; Adult; CpG Islands; Cyclic AMP Response Element Modulator; Epigenesis, Genetic; Female; Histones; Humans; Interleukin-17; Jurkat Cells; Lupus Erythematosus, Systemic; Methylation; Middle Aged; Response Elements; Th17 Cells

2012

Other Studies

29 other study(ies) available for isomethyleugenol and Lupus Erythematosus, Systemic

ArticleYear
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation.
    Bioengineered, 2022, Volume: 13, Issue:2

    Topics: Animals; CD40 Ligand; Disease Models, Animal; Female; Hydroxybutyrate Dehydrogenase; Lupus Erythematosus, Systemic; Methylation; Mice; Mice, Inbred BALB C; Th1 Cells; Th2 Cells

2022
Involvement of N6-methyladenosine modifications of long noncoding RNAs in systemic lupus erythematosus.
    Molecular immunology, 2022, Volume: 143

    Topics: Adenosine; Adult; Base Sequence; Case-Control Studies; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; Reproducibility of Results; RNA, Long Noncoding; RNA, Messenger; T-Lymphocytes

2022
The dynamic epigenetic regulation of the inactive X chromosome in healthy human B cells is dysregulated in lupus patients.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-15, Volume: 118, Issue:24

    Topics: Adolescent; Adult; Alleles; B-Lymphocytes; Child; Chromosomes, Human, X; Epigenesis, Genetic; Gene Expression Profiling; Heterochromatin; Histones; Humans; Lupus Erythematosus, Systemic; Lymphocyte Subsets; Lysine; Methylation; Middle Aged; RNA, Long Noncoding; Ubiquitin; X Chromosome Inactivation; Young Adult

2021
Methyl donor micronutrients, CD40-ligand methylation and disease activity in systemic lupus erythematosus: A cross-sectional association study.
    Lupus, 2021, Volume: 30, Issue:11

    Topics: Adult; CD40 Ligand; Choline; Cross-Sectional Studies; Cysteine; Diet Records; DNA Methylation; Female; Humans; Lupus Erythematosus, Systemic; Methionine; Methylation; Micronutrients; Middle Aged; Patient Acuity

2021
Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus.
    Oncotarget, 2017, Jul-25, Volume: 8, Issue:30

    Topics: Adult; CD11a Antigen; CD4-Positive T-Lymphocytes; Female; Gene Expression Regulation; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lupus Erythematosus, Systemic; Male; Methylation; Promoter Regions, Genetic; Protein Binding; RNA, Messenger

2017
Short-term cytokine stimulation reveals regulatory T cells with down-regulated Foxp3 expression in human peripheral blood.
    European journal of immunology, 2018, Volume: 48, Issue:2

    Topics: Arthritis, Rheumatoid; Blood Circulation; CD4-Positive T-Lymphocytes; Cells, Cultured; Down-Regulation; Flow Cytometry; Forkhead Transcription Factors; Humans; Immunotherapy; Interleukin-15; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Interleukin-7; Interleukin-7 Receptor alpha Subunit; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Methylation; Monitoring, Physiologic; T-Lymphocytes, Regulatory

2018
Critical role of transmethylation in TLR signaling and systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2013, Volume: 147, Issue:2

    Topics: Adenine; Animals; Antigen-Presenting Cells; Autoantibodies; B-Lymphocytes; Butyrates; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Female; Immunoglobulin G; Immunosuppressive Agents; Kidney; Lupus Erythematosus, Systemic; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Protein Processing, Post-Translational; Signal Transduction; Toll-Like Receptors

2013
Proteomic analyses and identification of arginine methylated proteins differentially recognized by autosera from anti-Sm positive SLE patients.
    Journal of biomedical science, 2013, May-04, Volume: 20

    Topics: Arginine; Autoantibodies; HeLa Cells; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Lupus Erythematosus, Systemic; Methylation; Proteomics; PTB-Associated Splicing Factor; RNA-Binding Proteins; Transfection

2013
Systemic lupus erythematosus patients contain significantly less igm against mono-methylated lysine than healthy subjects.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Female; Histones; Humans; Immunoglobulin G; Immunoglobulin M; Lupus Erythematosus, Systemic; Lysine; Male; Methylation

2013
The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:11

    Topics: Adult; Biomarkers; Disease Progression; Female; Forkhead Transcription Factors; Humans; Ikaros Transcription Factor; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; T-Lymphocytes, Regulatory; Young Adult

2013
The effect of mycophenolic acid on epigenetic modifications in lupus CD4+T cells.
    Clinical immunology (Orlando, Fla.), 2015, Volume: 158, Issue:1

    Topics: Acetylation; Adult; Case-Control Studies; CD11a Antigen; CD27 Ligand; CD4-Positive T-Lymphocytes; CD40 Ligand; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histone Deacetylases; Histones; Humans; Lupus Erythematosus, Systemic; Methylation; Middle Aged; Mycophenolic Acid; RNA, Messenger; Young Adult

2015
Monocyte enhancers are highly altered in systemic lupus erythematosus.
    Epigenomics, 2015, Volume: 7, Issue:6

    Topics: Binding Sites; DNA Methylation; Enhancer Elements, Genetic; Female; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Interferon Regulatory Factor-1; Interferons; Lupus Erythematosus, Systemic; Male; Methylation; Monocytes; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Transcription Initiation Site; Transcriptional Activation

2015
H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus.
    Clinical epigenetics, 2016, Volume: 8

    Topics: Chromatin Immunoprecipitation; Epigenesis, Genetic; Histones; Humans; Lupus Erythematosus, Systemic; Methylation; Monocytes; Oligonucleotide Array Sequence Analysis; Transcription Initiation Site; Transcription, Genetic; Transcriptome

2016
A central role of H3K4me3 extended chromatin domains in gene regulation.
    Epigenomics, 2016, Volume: 8, Issue:8

    Topics: Animals; Autoimmune Diseases; Binding Sites; Chromatin; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lupus Erythematosus, Systemic; Methylation

2016
Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
    Genes and immunity, 2008, Volume: 9, Issue:4

    Topics: Animals; CD11a Antigen; CD27 Ligand; Cell Separation; Cells, Cultured; Disease Models, Animal; Doxycycline; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Interferons; Lupus Erythematosus, Systemic; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Oligonucleotide Array Sequence Analysis; Repressor Proteins; RNA, Messenger; T-Lymphocytes

2008
Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus.
    Journal of biomedicine & biotechnology, 2010, Volume: 2010

    Topics: Adolescent; Adult; Azacitidine; Case-Control Studies; CD4-Positive T-Lymphocytes; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Interleukin-10; Interleukin-13; Lupus Erythematosus, Systemic; Male; Methylation; Polymerase Chain Reaction; Promoter Regions, Genetic

2010
Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:1

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Apoptosis; Autoantibodies; Chromatin; Epitope Mapping; Histones; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Methylation; Mice; Mice, Inbred MRL lpr; Molecular Sequence Data; Sequence Alignment; Tumor Cells, Cultured

2011
Lupus autoimmunity altered by cellular methylation metabolism.
    Autoimmunity, 2013, Volume: 46, Issue:1

    Topics: Animals; Autoimmunity; B-Lymphocytes; Cell Proliferation; Cytokines; Female; Humans; Lupus Erythematosus, Systemic; Lymphocyte Activation; Methylation; Mice; Mice, Inbred MRL lpr; Mice, Transgenic; S-Adenosylmethionine; T-Lymphocytes; Th1 Cells; Th2 Cells

2013
Autoantibodies to dsDNA cross-react with the arginine-glycine-rich domain of heterogeneous nuclear ribonucleoprotein A2 (hnRNP A2) and promote methylation of hnRNP A2.
    Rheumatology (Oxford, England), 2003, Volume: 42, Issue:1

    Topics: Amino Acid Sequence; Animals; Antibodies, Antinuclear; Antibodies, Monoclonal; Antigen-Antibody Reactions; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cytoplasm; Epitopes; Flow Cytometry; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Jurkat Cells; Lupus Erythematosus, Systemic; Methylation; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Protein-Arginine N-Methyltransferases; Rats; Tumor Cells, Cultured

2003
Arginine methylation of RNA helicase a determines its subcellular localization.
    The Journal of biological chemistry, 2004, May-28, Volume: 279, Issue:22

    Topics: Arginine; Autoantigens; Cell Nucleus; DEAD-box RNA Helicases; Humans; Lupus Erythematosus, Systemic; Methylation; Neoplasm Proteins; Protein Transport; RNA Helicases

2004
Demethylation of CD40LG on the inactive X in T cells from women with lupus.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Nov-01, Volume: 179, Issue:9

    Topics: Adult; CD27 Ligand; CD40 Ligand; DNA; Female; Gene Expression Regulation; Humans; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Sex Characteristics; T-Lymphocytes; X Chromosome Inactivation

2007
Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Cells, Cultured; DNA; Female; Humans; Interleukin-4; Interleukin-6; Lupus Erythematosus, Systemic; Male; Methylation; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes

2008
Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Mar-15, Volume: 154, Issue:6

    Topics: Animals; Autoantibodies; Azacitidine; Cell Line; Cytokines; Cytotoxicity, Immunologic; DNA; Enzyme-Linked Immunosorbent Assay; Female; Immunoglobulin G; Immunoglobulin M; Immunotherapy, Adoptive; Lupus Erythematosus, Systemic; Lymphocyte Activation; Methylation; Mice; Mice, Inbred AKR; Mice, Inbred NZB; Procainamide; Th2 Cells

1995
5-Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmune rheumatic diseases.
    Journal of chromatography, 1991, May-31, Volume: 566, Issue:2

    Topics: 5-Methylcytosine; Adult; Autoimmune Diseases; Chromatography, High Pressure Liquid; Cyclosporine; Cytosine; DNA; Female; Humans; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; Rheumatic Diseases; Synovial Membrane

1991
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:11

    Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmunity; DNA; DNA Modification Methylases; Female; Humans; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; T-Lymphocyte Subsets; T-Lymphocytes

1990
Low expression of human histocompatibility leukocyte antigen-DR is associated with hypermethylation of human histocompatibility leukocyte antigen-DR alpha gene regions in B cells from patients with systemic lupus erythematosus.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:4

    Topics: Antibodies, Antinuclear; Autoimmune Diseases; B-Lymphocytes; Cell Line; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Genes; Genes, MHC Class II; Herpesvirus 4, Human; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Lupus Erythematosus, Systemic; Methylation; RNA, Messenger; Tetrahydrofolate Dehydrogenase

1985
Phospholipid base exchange activity in the leukocyte membranes of patients with inflammatory disorders.
    The American journal of pathology, 1987, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Behcet Syndrome; Diacylglycerol Cholinephosphotransferase; Ethanolamine; Ethanolaminephosphotransferase; Ethanolamines; Female; Humans; Inflammation; Leukocytes; Lupus Erythematosus, Systemic; Male; Membrane Lipids; Methylation; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids

1987
Molecular basis of elevated c-myb expression in the abnormal L3T4-, Lyt-2- T lymphocytes of autoimmune mice.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Nov-15, Volume: 139, Issue:10

    Topics: Animals; Antigens, Surface; Autoimmune Diseases; DNA; Female; Gene Expression Regulation; Lupus Erythematosus, Systemic; Lymph Nodes; Lymphoproliferative Disorders; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; T-Lymphocytes

1987
Antibodies to deoxyribonucleic acid irradiated with ultraviolet light: detection by precipitins and immunofluorescence.
    Science (New York, N.Y.), 1968, Sep-27, Volume: 161, Issue:3848

    Topics: Animals; Antibodies; Chemical Precipitation; DNA; Fluorescent Antibody Technique; Hot Temperature; Immune Sera; Immunodiffusion; Lupus Erythematosus, Systemic; Methylation; Nucleic Acid Denaturation; Precipitin Tests; Rabbits; Radiation Effects; Radiochemistry; Serum Albumin, Bovine; Thymus Gland; Ultraviolet Rays

1968