isomethyleugenol has been researched along with Leukemia L 1210 in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (78.00) | 18.7374 |
| 1990's | 10 (20.00) | 18.2507 |
| 2000's | 1 (2.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, TH; Liu, JC; Plass, C; Potter, D; Smith, LT; Wang, SH; Wu, J; Wu, YZ | 1 |
| Momparler, LF; Momparler, RL; Samson, J | 1 |
| Abbasi, MM; Beisler, JA; Glazer, RI; Peale, AL | 1 |
| Glazer, RI; Hartman, KD | 3 |
| Jones, PA; Momparler, RL; Wilson, VL | 1 |
| Lu, LJ; Randerath, K | 1 |
| Boyle, JM; Durrant, LG; Margison, GP | 1 |
| Inui, T; Matsuzawa, Y; Oki, T; Shimauchi, Y; Tanaka, H; Yoshioka, T | 1 |
| Glazer, RI; Stern, HJ | 1 |
| Andrei, G; Balzarini, J; Chen, X; De Clercq, E; Ikeda, S; Rao, J; Schneller, SW; Siddiqi, SM; Snoeck, R | 1 |
| Kohda, K; Terashima, I; Yamagami, N; Yamagata, Y | 1 |
| Bernacki, RJ; Hillman, MJ; Korytnyk, W; Sharma, M | 1 |
| Bittman, R; Marino-Albernas, JR; Mayhew, E; Peters, A | 1 |
| Arai, M; Haneishi, T; Itoh, Y; Katayama, T; Miura, T | 1 |
| Avakian, KA; Parkhomenko, II; Zhizhina, GP | 1 |
| Glazer, RI; Peale, AL | 3 |
| Agarwal, RP; Crabtree, GW; Lewis, AF; Parks, RE; Townsend, LB; Wotring, LL | 1 |
| Lee, AS; Robins, MJ | 1 |
| Johdo, O; Naganawa, H; Okamoto, R; Sawa, T; Takeuchi, T; Tone, H; Yoshimoto, A | 1 |
| Johdo, O; Okamoto, R; Takeuchi, T; Tone, H; Yoshimoto, A | 1 |
| Beghetti, R; Bianchi, R; Citti, L; D'Incalci, M; Fioretti, MC; Puccetti, P; Romani, L | 1 |
| Coward, JK; Lakanen, JR; Pegg, AE | 1 |
| Rohr, J; Zeeck, A | 1 |
| Borchardt, RT; Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Allegrucci, M; Borri Voltattorni, C; Dominici, P; Fioretti, MC; Puccetti, P; Romani, L | 1 |
| Avramis, VI; Powell, WC | 1 |
| Fioretti, MC; Fuschiotti, P; Puccetti, P; Romani, L | 1 |
| Funderburk, SJ; Klisak, I; Smith, SS; Tolberg, ME | 1 |
| Danenberg, PV; Ibric, LL; Peterson, AR; Peterson, H | 1 |
| Kramer, DL; Porter, CW; Sufrin, JR | 1 |
| Broggini, M; Catapano, CV; Citti, L; D'Incalci, M; Erba, E; Mariani, L; Ponti, M | 1 |
| Kedzierska, B; Kulikowski, T; Rode, W; Shugar, D | 1 |
| Jones, PA; Kautiainen, TL | 2 |
| Dysard, R; Kessel, D | 1 |
| Gullion, D; Kann, HE; Kohn, KW; Widerlite, L | 1 |
| Adamson, RH; Gallo, RC; Herrera, F | 1 |
| Agrawal, KC; Cushley, RJ; Lipsky, SR; Sartorelli, AC; Wheaton, JR | 1 |
| Goldman, ID | 1 |
| Burchenal, JH; Giner-Sorolla, A | 1 |
| Bertino, JR; Nixon, PF | 1 |
| Bhuyan, BK | 1 |
| Himmelfarb, P; Roberts, D; Thayer, PS | 1 |
| Allan, PW; Bennett, LL | 1 |
| Baker, BR; Vermeulen, NM | 2 |
1 review(s) available for isomethyleugenol and Leukemia L 1210
| Article | Year |
|---|---|
Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis.
Topics: Alkylating Agents; Animals; Azaguanine; Cell Line; Cell Survival; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Deoxyribonucleosides; DNA; Drug Resistance; Drug Synergism; Floxuridine; Leukemia L1210; Lung; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1985 |
49 other study(ies) available for isomethyleugenol and Leukemia L 1210
| Article | Year |
|---|---|
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.
Topics: Acetylation; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation; Gene Silencing; Histones; Hydroxamic Acids; Leukemia L1210; Lysine; Methylation; Mice; Mice, Inbred DBA; Oligonucleotide Array Sequence Analysis; Protein Processing, Post-Translational | 2007 |
Comparison of the antileukemic activity of 5-AZA-2'-deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-azacytidine against L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; DNA, Neoplasm; Leukemia L1210; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred DBA | 1984 |
The effect of 5-azacytidine and dihydro-5-azacytidine on nuclear ribosomal RNA and poly(A) RNA synthesis in L1210 cells in vitro.
Topics: Adenosine; Animals; Azacitidine; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methylation; Mice; Poly A; RNA; RNA, Heterogeneous Nuclear; RNA, Messenger; RNA, Ribosomal; Uridine | 1980 |
The comparative effects of 5-azacytidine and dihydro-5-azacytidine on 4 S and 5 S nuclear RNA.
Topics: Animals; Azacitidine; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Leukemia L1210; Methylation; Mice; Molecular Weight; RNA, Neoplasm | 1980 |
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Adult; Animals; Cell Nucleus; Deoxyadenosines; Homocysteine; Humans; Hydrolases; Leukemia L1210; Methylation; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1980 |
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action.
Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice | 1983 |
Long term instability and molecular mechanism of 5-azacytidine-induced DNA hypomethylation in normal and neoplastic tissues in vivo.
Topics: Animals; Azacitidine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Kinetics; Leukemia L1210; Liver; Liver Regeneration; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Inbred DBA | 1984 |
Effects of 5-methylnicotinamide on mouse L1210 cells exposed to N-methyl-N-nitrosourea: mutation induction, formation and removal of methylation products in DNA, and unscheduled DNA synthesis.
Topics: Animals; Cells, Cultured; DNA Repair; DNA, Neoplasm; Leukemia L1210; Methylation; Methylnitrosourea; Mice; Mutagens; Niacinamide; Nitrosourea Compounds; Purines | 1981 |
Chemical modification of anthracycline antibiotics. I. Demethoxycarbonylation, 10-epimerization and 4-o-methylation of aclacinomycin A.
Topics: Aclarubicin; Animals; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Depression, Chemical; DNA, Neoplasm; Leukemia L1210; Methylation; Molecular Conformation; Naphthacenes; RNA, Neoplasm; Structure-Activity Relationship | 1980 |
The effect of 5-fluorouracil on the synthesis and methylation of low molecular weight nuclear RNA in L1210 cells.
Topics: Adenosine; Animals; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Fluorouracil; Leukemia L1210; Methylation; Mice; Molecular Weight; RNA, Neoplasm; Time Factors | 1980 |
Inhibition of methylation of nuclear ribonucleic acid in L1210 cells by tubercidin, 8-azaadenosine and formycin.
Topics: Adenosine; Animals; Antineoplastic Agents; Cell Nucleus; Cells, Cultured; DNA, Neoplasm; Formycins; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; Tubercidin | 1980 |
3-deaza- and 7-deaza-5'-noraristeromycin and their antiviral properties.
Topics: Adenosine; Animals; Antiviral Agents; Cattle; Cell Division; Cells, Cultured; Chlorocebus aethiops; HeLa Cells; HIV-1; HIV-2; Humans; Leukemia L1210; Male; Methylation; Mice; Microbial Sensitivity Tests; T-Lymphocytes; Vero Cells | 1995 |
Demethylation of O6-methylguanine in DNA by O6-methylguanine-DNA methyltransferase: synthesis and characterization of O6,9-dimethylguanine coordinated with cis-platin at the N7-position.
Topics: Animals; Cisplatin; DNA; DNA Damage; Guanine; Kinetics; Leukemia L1210; Methylation; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds | 1994 |
Fluorinated carbohydrates as potential plasma membrane modifiers. Synthesis of 3-deoxy-3-fluoro derivatives of 2-acetamido-2-deoxy-D-hexopyranoses.
Topics: Acetylglucosamine; Animals; Antineoplastic Agents; Cell Membrane; Deoxyglucose; Leukemia L1210; Methylation; Mice; N-Acetylneuraminic Acid; Rhamnose; Sialic Acids; Tumor Cells, Cultured | 1993 |
Synthesis and growth inhibitory properties of glycosides of 1-O-hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET-18-OCH3 (edelfosine).
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Female; Glycosides; Humans; Indicators and Reagents; Leukemia L1210; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Methylation; Mice; Molecular Structure; Phospholipid Ethers; Tumor Cells, Cultured | 1996 |
New antibiotics, enaminomycins A, B and C. II. Physico-chemical and biological properties.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Bacillus subtilis; Chemical Phenomena; Chemistry; In Vitro Techniques; Leukemia L1210; Male; Methylation; Mice; Microbial Sensitivity Tests; Proteus vulgaris; Quinones | 1978 |
[Secondary structure and methylation of DNA in reinoculated tumors and cultures of embryonic cells transformed by oncogenic viruses].
Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; DNA; DNA, Neoplasm; Embryo, Mammalian; Leukemia L1210; Liver; Methylation; Mice; Nucleic Acid Conformation; Polyomavirus; Rats; Simian virus 40 | 1979 |
Cordycepin and xylosyladenine: inhibitors of methylation of nuclear RNA.
Topics: Adenosine; Animals; Cell Nucleus; Deoxyadenosines; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; Xylose | 1978 |
Evidence that xylosyladenine affects methylation by inhibition of S-adenosyl-L-methionine synthesis.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Nucleus; Coformycin; Deoxyadenosines; In Vitro Techniques; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; S-Adenosylmethionine; Xylose | 1979 |
N-Methylformycins. Reactivity with adenosine deaminase, incorporation into intracellular nucleotides of human erythrocytes and L 1210 cells and cytotoxicity to L 1210 cells.
Topics: Adenosine Deaminase; Animals; Antibiotics, Antineoplastic; Erythrocytes; Formycins; Humans; In Vitro Techniques; Kinetics; Leukemia L1210; Methylation; Mice; Nucleoside Deaminases; Nucleotides; Structure-Activity Relationship | 1979 |
The effect of 5-fluorouracil on the synthesis of nuclear RNA in L1210 cells in vitro.
Topics: Animals; Cell Nucleus; Fluorouracil; In Vitro Techniques; Leukemia L1210; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Poly A; RNA, Neoplasm; Uridine | 1979 |
Nucleic acid related compounds. 17.3-Deazuridine. Stannous chloride catalysis of cis-diol vs. phenolic base methylation with diazomethane.
Topics: 3-Deazauridine; Animals; Diazomethane; Enterococcus faecalis; Escherichia coli; Glycols; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Pyridones; Ribonucleosides; Structure-Activity Relationship; Tin; Uridine | 1975 |
Photochemically obtained N-demethyl derivatives of anthracyclines.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA Replication; DNA, Neoplasm; Leukemia L1210; Magnetic Resonance Spectroscopy; Methylation; Photochemistry; RNA, Neoplasm; Structure-Activity Relationship; Tumor Cells, Cultured | 1992 |
Production of new anthracycline antibiotics by microbial 4-O-methylation using a specific daunorubicin-negative mutant.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Biotransformation; Daunorubicin; DNA Replication; DNA, Neoplasm; Drug Resistance, Microbial; Drug Screening Assays, Antitumor; Leukemia L1210; Methylation; Mice; Streptomyces; Tumor Cells, Cultured | 1992 |
O6-methylguanine-DNA methyltransferase activity and induction of novel immunogenicity in murine tumor cells treated with methylating agents.
Topics: Alkylating Agents; Alkylation; Animals; DNA Damage; DNA Repair; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1992 |
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
Topics: Animals; Cell Division; Cell Line, Transformed; Colonic Neoplasms; Eflornithine; Humans; Leukemia L1210; Methylation; Mice; Putrescine; Spermidine; Spermine; Spermine Synthase; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Structure-activity relationships of elloramycin and tetracenomycin C.
Topics: Animals; Anthraquinones; Anti-Bacterial Agents; Cell Division; Glycosylation; Hydrolysis; Leukemia L1210; Methylation; Mice; Naphthacenes; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Combined modulation of S-adenosylmethionine biosynthesis and S-adenosylhomocysteine metabolism enhances inhibition of nucleic acid methylation and L1210 cell growth.
Topics: Adenosine; Animals; Cell Division; DNA, Neoplasm; Homocysteine; Leukemia L1210; Methylation; Polyamines; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors | 1990 |
DNA methylating activity in murine lymphoma cells treated with xenogenizing chemicals.
Topics: Animals; Azacitidine; Carmustine; DNA, Neoplasm; Leukemia L1210; Male; Methylation; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Triazenes | 1987 |
Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice.
Topics: Animals; Azacitidine; Bone Marrow; Brain; Chromatography, High Pressure Liquid; DNA, Neoplasm; Erythrocytes; Intestinal Mucosa; Kidney; Leukemia L1210; Liver; Lung; Male; Methylation; Mice; Muscles; Myocardium; Spleen; Testis; Tissue Distribution; Tumor Cells, Cultured | 1988 |
Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Clone Cells; Cytosine; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Phenotype; Triazenes | 1989 |
Structural organization and DNA methylation patterning within the mouse L1 family.
Topics: Animals; Base Sequence; Cell Line; Chromosomes; DNA; DNA Restriction Enzymes; DNA, Recombinant; Friend murine leukemia virus; Leukemia L1210; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Methylation; Mice; Nucleic Acid Hybridization; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Repetitive Sequences, Nucleic Acid; Spleen | 1987 |
Relative effects of S-adenosylmethionine depletion on nucleic acid methylation and polyamine biosynthesis.
Topics: Aminobutyrates; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methionine Adenosyltransferase; Methylation; Mice; Nucleic Acids; Polyamines; S-Adenosylmethionine | 1987 |
In vitro and in vivo methazolastone-induced DNA damage and repair in L-1210 leukemia sensitive and resistant to chloroethylnitrosoureas.
Topics: Animals; Antineoplastic Agents; Carmustine; Dacarbazine; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Flow Cytometry; Leukemia L1210; Methylation; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide | 1987 |
Inhibition of mammalian tumour thymidylate synthetase by 2'-deoxyuridine 5'-phosphate analogues.
Topics: Animals; Deoxyuracil Nucleotides; HeLa Cells; Humans; Leukemia L1210; Mathematics; Methylation; Thymidylate Synthase | 1986 |
DNA methylation in mammalian nuclei.
Topics: Animals; Cell Nucleus; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; DNA, Neoplasm; Kinetics; Leukemia L1210; Male; Methylation; Mice; Mice, Inbred Strains | 1985 |
Effects of DNA binding proteins on DNA methylation in vitro.
Topics: Animals; Cell Nucleus; Chromatin; DNA-Binding Proteins; DNA, Neoplasm; Histones; Leukemia L1210; Methylation; Mice; S-Adenosylmethionine; Tritium | 1985 |
Effects of camptothecin on RNA synthesis in L-1210 cells.
Topics: Animals; Camptothecin; Carbon Isotopes; Centrifugation, Density Gradient; Clone Cells; Leukemia L1210; Methylation; Mice; Nucleotides; Phosphorus Isotopes; RNA; RNA, Ribosomal; Time Factors; Uridine | 1973 |
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds on nuclear RNA metabolism.
Topics: Animals; Carmustine; Cell Nucleolus; Cell Nucleus; Cells, Cultured; Depression, Chemical; Leukemia L1210; Methylation; Mice; Nitrosourea Compounds; RNA, Neoplasm; Structure-Activity Relationship; Time Factors | 1974 |
Uptake of transfer ribonucleic acid by normal and leukemic cells.
Topics: Animals; Autoradiography; Biological Transport; Carbon Isotopes; Cell Line; Chromatography, Gel; Escherichia coli; Humans; In Vitro Techniques; Kinetics; Leukemia L1210; Ligases; Lymphocytes; Methylation; Mice; Microscopy, Electron; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Transferases | 1970 |
Potential antitumor agents. 5. Methylated -(N)-heterocyclic carboxaldehyde thiosemicarbazones.
Topics: Animals; Antineoplastic Agents; Isoquinolines; Leukemia L1210; Magnetic Resonance Spectroscopy; Methylation; Mice; Mice, Inbred Strains; Pyridines; Structure-Activity Relationship; Thiosemicarbazones | 1972 |
A model system for the study of heteroexchange diffusion: methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells.
Topics: Animals; Binding Sites; Biological Transport; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cells, Cultured; Chromatography, DEAE-Cellulose; Diffusion; Folic Acid; Folic Acid Antagonists; Formates; Kinetics; Leukemia L1210; Methotrexate; Methylation; Mice; Models, Biological; Tritium | 1971 |
Substituted hydroxylaminopurines and related derivatives. Synthesis and screening tests.
Topics: Animals; Antineoplastic Agents; Fluorine; Hydroxylamines; Leukemia L1210; Leukemia, Experimental; Methylation; Mice; Nucleosides; Osteosarcoma; Purines; Sarcoma, Experimental; Structure-Activity Relationship; Sulfhydryl Compounds | 1971 |
Enzymic preparations of radiolabeded (+)-L-5-methyltetrahydrofolate and (+)-L-5-formyltetrahydrofolate.
Topics: Animals; Carbon Isotopes; Cell Line; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Clostridium; Folic Acid; Isotope Labeling; Leucovorin; Leukemia L1210; Methods; Methylation; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Stereoisomerism; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays | 1971 |
The action of streptozotocin on mammalian cells.
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Cell Division; Chromosome Aberrations; Culture Techniques; Cytogenetics; DNA Nucleotidyltransferases; DNA, Neoplasm; Glucose; Leukemia L1210; Methylation; Mice; Phosphotransferases; RNA, Neoplasm; Thymidine Kinase; Transferases; Uracil Nucleotides | 1970 |
Effects of perfusion with amethopterin on L1210 leukemia cells in spin filter culture.
Topics: Agar; Animals; Binding Sites; Cell Count; Cell Division; Centrifugation; Clone Cells; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Leukemia L1210; Methods; Methotrexate; Methylation; Mice; Perfusion; Tetrahydrofolate Dehydrogenase; Time Factors; Transferases; Tritium; Uracil Nucleotides | 1970 |
Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine.
Topics: Adenocarcinoma; Animals; Chromatography, Paper; Electrophoresis; Glucosyltransferases; L Cells; Leukemia L1210; Liver Neoplasms; Mercaptopurine; Methylation; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Purines; Sulfur Isotopes | 1971 |
Irreversible enzyme inhibitors. CXXXIV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonyl-phenylureido)phenoxymet
Topics: Animals; Benzene Derivatives; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Chlorine; Fluorides; Folic Acid Antagonists; Leukemia L1210; Liver; Methylation; Mice; Pyrimidines; Sulfonic Acids; Time Factors | 1969 |
Irreversible enzyme inhibitors. 138. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-- 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride.
Topics: Animals; Benzene Derivatives; Binding Sites; Chemical Phenomena; Chemistry; Chlorine; Fluorides; Folic Acid Antagonists; Leukemia L1210; Liver; Methylation; Mice; Pyrimidines; Sulfonic Acids | 1969 |