isomethyleugenol has been researched along with Invasiveness, Neoplasm in 105 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (4.76) | 18.7374 |
| 1990's | 3 (2.86) | 18.2507 |
| 2000's | 10 (9.52) | 29.6817 |
| 2010's | 57 (54.29) | 24.3611 |
| 2020's | 30 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Chen, S; Chen, Z; Hu, X; Hu, Y; Lu, M; Pan, B; Shen, X; Shi, X; Sun, X; Tong, X; Xue, X | 1 |
| Ando, T; Motoo, I; Nanjo, S; Ushijima, T; Yamashita, S; Yasuda, I | 1 |
| Cai, S; Chen, W; Feng, Z; Li, Y; Lu, JJ; Sun, Y; Wang, Q; Xie, J; Ye, Z | 1 |
| Ji, T; Liu, A; Mao, X; Weng, Y | 1 |
| Diao, H; Hao, N; Koropatnick, J; Liu, Q; Maleki Vareki, S; Min, J; Min, W; Raphael, J; Sang, Y; Wang, Z; Xiong, J; Xu, D; Zhang, Y; Zheng, X | 1 |
| Hu, Y; Jiang, F; Liu, X; Wang, M; Wu, C | 1 |
| Xue, J; Yi, J; Zhu, X | 1 |
| Fan, J; Qin, B; Ren, S; Shao, H; Shi, Y; Sun, J; Wang, X; Ye, L; Zhao, X | 1 |
| Guo, X; Lu, R; Shi, Y; Wu, Q; Yang, J; Ye, G; Zeng, Y | 1 |
| Chen, W; Lou, G; Mi, S; Wang, H; Wei, W; Xue, M; Zhang, Z | 1 |
| Cui, Y; Dai, M; Hu, Y; Kong, W; Wang, X; Wu, H; Wu, J; Yu, B; Yu, X; Zhang, H; Zheng, Y | 1 |
| Chen, T; Li, T; Sun, L; Yu, J | 1 |
| Chen, X; Dong, F; Hu, DN; Jin, S; Liu, Q; Luo, G; Reinach, PS; Wang, J; Wang, S; Xu, W; Yan, D; Zhao, Y | 1 |
| Gao, G; Liang, JY; Liu, P; Tang, H; Xie, X; Yang, A; Yang, L; Zheng, S; Zou, Y | 1 |
| Ban, Y; Cai, J; Hu, M; Li, G; Li, J; Li, X; Mei, Y; Tan, P; Tan, Y; Xiang, B; Xiong, W; Yi, M; Zeng, Z; Zhou, Y | 1 |
| Jiang, S; Liu, J; Ma, G; Wang, Q; Zhang, Y; Zheng, J | 1 |
| Chen, C; Geng, W; Guo, H; Wang, Q; Wang, S; Wang, Z; Xu, K | 1 |
| Jeong, CW; Jeong, SH; Kim, BC; Kim, HH; Ku, JH; Kwak, C; Lee, KH | 1 |
| Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F | 1 |
| Jiang, X; Li, D; Yang, Z | 1 |
| Chen, K; Li, J; Liu, J; Yu, A; Zhang, X; Zhang, Z | 1 |
| Xie, Y; Zhao, W | 1 |
| An, N; Chen, XJ | 1 |
| Du, W; Gao, A; Guo, M; Herman, JG; Jiao, S; Wang, L; Zhang, L | 1 |
| Chong, T; Guan, Y; Ma, Y; Xu, F; Xue, L; Yang, X; Zhang, P | 1 |
| He, Y; Hu, Y; Liu, W; Su, Y; Xiao, B | 1 |
| Guan, Q; Guo, H; Hong, D; Ji, J; Liu, J; Ren, Q; Zhang, C; Zhang, Q | 1 |
| Ma, J; Ma, XX; Yang, D | 1 |
| Bassi, C; Carbonare, LD; Cheri, S; Deiana, M; Giacomazzi, A; Giacomello, L; Grasso, S; Guardini, V; Guzzi, F; Innamorati, G; Lawlor, RT; Leone, BE; Malerba, G; Malleo, G; Malpeli, G; Mori, A; Paiella, S; Parenti, M; Rusev, B; Salvia, R; Serena, M; Valenti, MT; Wilkie, TM; Zanotto, M; Zipeto, D | 1 |
| Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z | 1 |
| Chen, YT; Chu, XY; Xiang, D; Zhao, XY | 1 |
| Chen, L; Deng, X; Gao, F; Li, B; Li, L; Li, X; Liang, T; Pan, Y; Ren, Y; Wang, J; Yang, D; Yang, Y; Zhai, S; Zhang, S; Zhang, X; Zhao, J; Zheng, Y; Zhou, P | 1 |
| Chen, K; He, J; Huang, Y; Li, B; Liu, J; Liu, Q; Liu, Z; Qi, J; Qin, Y; Wei, L; Yu, X; Zhao, R | 1 |
| Li, T; Liu, Y; Shi, Y; Wang, L; Wang, T; Wang, X; Wang, Y; Yang, Y | 1 |
| Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G | 1 |
| Huang, Z; Sun, B; Zeng, Q; Zhang, Y; Zhao, DW | 1 |
| Deng, J; Jiao, X; Li, J; Qiu, D; Sun, Z; Wan, X; Xia, Z; Yang, R | 1 |
| Cao, L; Ji, J; Nakatsu, G; Wang, S; Wang, X; Wong, KC; Wong, S; Yu, J; Zhang, Y | 1 |
| Bähr, O; Belka, C; Braun, C; Gerlach, R; Glas, M; Goldbrunner, R; Hänel, M; Hattingen, E; Hau, P; Herrlinger, U; Junold, N; Kebir, S; Kortmann, RD; Krex, D; Mack, F; Niessen, M; Proescholdt, M; Rohde, V; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schmidt-Graf, F; Steinbach, JP; Stuplich, M; Tzaridis, T; Vatter, H; Weyerbrock, A | 1 |
| Chen, T; Han, X; Ren, G; Tang, J | 1 |
| Bi, J; Cai, Q; Chen, C; Dong, W; He, W; Huang, J; Jiang, N; Li, H; Lin, T; Liu, H; Su, F; Wang, B; Zhang, B; Zhao, Y; Zhong, G | 1 |
| Hu, X; Zhao, X | 1 |
| He, J; Li, WY; Wang, JX; Yan, LZ; Yang, Y; Zhang, J; Zhang, SY | 1 |
| Guo, S; Meng, XY; Piao, HY; Wang, Y; Wu, Y; Yang, D; Zhang, J; Zhao, Y; Zheng, ZC | 1 |
| Chang, J; Liu, Y; Sun, J; Wang, H; Wang, M; Wang, W; Xiong, J; Ye, D; Yu, H; Yu, T; Zhao, C; Zhou, H | 1 |
| Cao, W; Chen, HY; Cui, Y; Du, W; Fang, JY; Han, ZG; Hong, J; Lin, YW; Ren, LL; Shen, N; Sun, DF; Sun, TT; Wang, JL; Wang, YC; Wang, ZH; Weng, YR; Xiong, H; Xu, J; Yu, YN; Zou, W | 1 |
| Bachvarov, D; Bachvarova, M; Gregoire, J; Keita, M; Morin, C; Plante, M; Renaud, MC; Sebastianelli, A; Trinh, XB | 1 |
| Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y | 1 |
| Han, X; Huangyang, P; Jia, H; Shang, Y; Sun, L; Yan, R; Yang, X; Yu, N | 1 |
| Hashimoto, T; Kimura, S; Toyono, M; Usuba, O; Yamakawa, M | 1 |
| Cheng, EH; Dong, Y; Hsieh, JJ; Liu, H; Sasagawa, S; Takeda, S; Trainor, PA | 1 |
| Alam, H; Cascone, T; Chan, CH; Chung, J; Dhar, SS; Erez, B; Giri, D; Giri, U; Heymach, JV; Hung, MC; Kim, JH; Lee, MG; Li, N; Lin, HK; Multani, AS; Saigal, B; Wagner, KW; Wei, Y; Wu, X; Ye, Y | 1 |
| Chan, CH; Dhar, SS; Gu, B; Kim, JH; Lee, MG; Lee, SH; Lin, HK; Sharma, A | 1 |
| Chen, HX; Liu, H; Wang, S; Wang, Z | 1 |
| Aburatani, H; Fukayama, M; Hayashi, A; Ishikawa, S; Kimura, H; Kokudo, N; Morikawa, T; Nagae, G; Nishi, A; Sakamoto, Y; Shibahara, J; Yamauchi, N | 1 |
| He, L; Kan, M; Liu, F; Liu, Y; Niu, X; Tao, L; Zhan, L; Zhang, D; Zhang, Z; Zhou, D; Zhou, Y | 1 |
| Hu, C; Jiang, F; Li, Y; Li, Z; Mu, J; Ning, S; Si, L; Wang, X; Ye, X | 1 |
| Beninato, T; Crowley, MJ; Elemento, O; Evans, T; Fahey, TJ; Finnerty, B; Kleiman, DA; Kumar, R; Lieberman, MD; Liu, YF; Panarelli, NC; Seandel, M; Sultan, S; Zarnegar, R | 1 |
| Hamada, M; Hieda, M; Kimura, H; Matsumoto, A; Matsuura, N; Nishioka, Y; Ogihara, E; Shinchi, Y; Tsujimoto, M; Yokoyama, Y; Yoshidome, K | 1 |
| Fan, E; Li, E; Li, L; Wang, G; Xie, J; Xu, L; Zhang, K; Zhao, Y; Zhu, M | 1 |
| Hu, Z; Liu, Y; Qiu, J; Xiong, Z; Zheng, J; Zhu, Z | 1 |
| Gaforio, JJ; López-Biedma, A; Sánchez-Quesada, C | 1 |
| Jiang, X | 1 |
| Brambert, PR; Calafiore, G; Desai, CV; Godley, LA; Hameed, R; Kelpsch, DJ; Raimondi, SL | 1 |
| Kampilafkos, P; Kefalopoulou, Z; Lakoumentas, J; Melachrinou, M; Sotiropoulou-Bonikou, G | 1 |
| Lee, EJ; Lee, H | 1 |
| Akter, KA; Hamaguchi, M; Hyodo, T; Ito, S; Mansour, MA; Senga, T | 1 |
| Fan, Y; Liu, Y; Mu, X; Qin, Y; Shen, B; Tan, M; Zhang, F | 1 |
| Fan, R; Gao, W; Guo, Y; Mu, S; Qin, G; Sun, Y; Wang, B; Wang, G; Wu, H; Xu, Z; Zhang, Z | 1 |
| Chen, H; Gupta, V; Lorton, B; Shechter, D | 1 |
| Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L | 1 |
| Giaccia, AJ | 1 |
| Chen, X; Fan, LN; Huo, Y; Ji, G; Li, YF; Qin, WW; Wang, T; Wang, W; Wen, WH; Xi, WJ; Xiao, X; Yang, AG; Yang, F | 1 |
| Castellano, D; Costa, C; de la Rosa, F; Duarte, J; Dueñas, M; Fernández-Grajera, M; López-Calderón, FF; Martínez-Fernández, M; Muñoz, HG; Paramio, JM; Rubio, C; Saiz-Ladera, C; Segovia, C; Villacampa, F | 1 |
| Abdelghany, MK; Ahmed, RA; Ammar, AA; Ball, GR; Collins, HM; Ellis, IO; Elsheikh, SE; Garibaldi, JM; Grainge, MJ; Green, AR; Heery, DM; Martinez-Pomares, L; Paish, CE; Powe, DG; Rakha, EA; Soria, D | 1 |
| Aozasa, K; Ikeda, J; Inoue, M; Morii, E; Oda, T; Okumura, M; Qiu, Y; Tian, T | 1 |
| Bommi, PV; Dimri, GP; Dimri, M; Khandekar, JD; Sahasrabuddhe, AA | 1 |
| Becker, A; Buettner, R; Janzer, A; Kirfel, J; Lim, S; Schüle, R; Zimmer, A | 1 |
| Argani, P; Brzoska, P; Chang, HY; Gupta, RA; Horlings, HM; Hung, T; Kim, J; Kong, B; Li, R; Rinn, JL; Shah, N; Sukumar, S; Tsai, MC; van de Vijver, MJ; Wang, KC; Wang, Y; West, RB; Wong, DJ | 1 |
| Kataoka, H; Kitano, H; Kunimoto, Y; Nakano, S; Oshimura, M; Shimada, Y | 1 |
| Anastassiou, D; Kim, H; Varadan, V; Watkinson, J | 1 |
| Dong, ZM; Fang, XH; Ge, MH; Hu, FJ; Li, P; Ling, ZQ; Mao, WM; Zhao, X | 1 |
| Bastian, PJ; Ellinger, J; Fechner, G; Heukamp, LC; Müller, SC; Rogenhofer, S; Schneider, AC; von Ruecker, A | 1 |
| Chaussepied, M; Chluba, J; Cock-Rada, AM; Janski, N; Langsley, G; Medjkane, S; Perichon, M; Weitzman, JB; Yousfi, N | 1 |
| Dong, C; Evers, BM; Rychahou, PG; Wang, Y; Wu, Y; Yao, J; Yu, Y; Zhou, BP | 1 |
| Ezponda, T; Kelleher, NL; Licht, JD; Martinez-Garcia, E; Min, DJ; Neri, A; Popovic, R; Shah, MY; Will, C; Yu, J; Zheng, Y | 1 |
| Kong, HK; Park, JH; Yoon, S | 1 |
| Gong, Y; Hu, H; Ji, Q; Jiang, B; Li, X; Liu, Q; Liu, R; Shang, Y; Shao, C; Wang, Y; Yang, Y; Yuan, J; Zhao, W; Zou, Y | 1 |
| Liang, X; Liu, T; Liu, XS; Liu, Y; Ma, Y; Niu, M; Pang, D; Ren, Y; Shan, M; Song, Q; Sun, Q; Sun, S; Wei, W; Xia, B; Yang, L; Yang, Y; Zhang, G; Zhang, X; Zhang, Y | 1 |
| Goggins, M; Maehara, N; Sato, N; Su, GH | 1 |
| Chen, J; Ebert, MP; Hoffmann, J; Krüger, S; Lendeckel, U; Malfertheiner, P; Pastorekova, S; Rocco, A; Röcken, C | 1 |
| Arai, M; Kato, Y; Konishi, F; Miki, Y; Nagai, H; Noda, H; Togashi, K; Yoshikawa, H | 1 |
| Adachi, Y; Furihata, M; Ohtsuki, Y; Sonobe, H; Takeuchi, T | 1 |
| Hirohashi, S; Shibata, T | 1 |
| Jass, JR; Minoo, P; Moyer, MP | 1 |
| Hesheng, L; Jie, G; Lei, S; Xiaojun, T; Zhixiang, S | 1 |
| Hirohashi, S; Kanai, Y; Ochiai, A; Shimoyama, Y; Sugimura, T; Yoshiura, K | 1 |
| Ito, N; Montesano, R; Ogawa, K; Shibata, MA; Shirai, T; Takahashi, S; Tsuda, H; Wild, CP | 1 |
| Clark, S; Jackson, P; Kingsley, E; Millar, D; Ow, K; Russell, PJ; Yardley, G | 1 |
| Akedo, H; Ashida, Y; Inoue, H; Isoai, A; Kido, J; Kumagai, H; Shinkai, K | 1 |
| Akedo, H; Horai, T; Inoue, H; Mukai, M; Nishikawa, S; Ohigashi, H; Shinkai, K; Takeda, Y | 1 |
| Collard, JG; Habets, GG; Scholtes, E; van der Kammen, R | 1 |
| Del Senno, L; Hanau, S; Maestri, I; Piva, R; Reggiani, A; Romano, A; Russo, G | 1 |
| Guirguis, RA; Liotta, LA; Schiffmann, E | 1 |
| Frost, P; Kendal, WS | 1 |
6 review(s) available for isomethyleugenol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer.
Topics: Adenosine; Cell Physiological Phenomena; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Methylation; Methyltransferases; Models, Biological; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Biosynthesis; Radiation Tolerance; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Neoplasm | 2020 |
Upregulation of lncRNA NIFK-AS1 in hepatocellular carcinoma by m
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Methylation; Methyltransferases; Molecular Targeted Therapy; Neoplasm Invasiveness; Nuclear Proteins; RNA, Long Noncoding; Sorafenib; Up-Regulation | 2021 |
[E-cadherin cell adhesion system in human cancer].
Topics: Actinin; Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Delta Catenin; Gene Expression Regulation, Neoplastic; Humans; Methylation; Microfilament Proteins; Mutation; Neoplasm Invasiveness; Neoplasms; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Signal Transduction | 2006 |
Genetic basis of T-lymphoma invasion.
Topics: Animals; Chromosomes, Human, Pair 7; DNA, Neoplasm; Humans; Hybridomas; Lymphoma; Methylation; Mice; Mutation; Neoplasm Invasiveness; Oncogenes; T-Lymphocytes; Transfection; Tumor Cells, Cultured | 1989 |
Tumor autocrine motility factor.
Topics: Cell Line; Cell Movement; Glucose-6-Phosphate Isomerase; Humans; Melanoma; Membrane Proteins; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Oncogenes | 1986 |
Genetic instability and tumor progression.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Clone Cells; DNA, Neoplasm; Gene Expression Regulation; Humans; Methylation; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Oncogenes; Precancerous Conditions | 1986 |
1 trial(s) available for isomethyleugenol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cell Growth Processes; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiotherapy; Temozolomide; Tumor Suppressor Proteins | 2018 |
98 other study(ies) available for isomethyleugenol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Topics: 5-Methylcytosine; Aged; Amino Acid Sequence; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Protein Stability; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Stomach Neoplasms; Subcellular Fractions; Sumoylation; Ubiquitins | 2021 |
Methylation silencing of ULK2 via epithelial-mesenchymal transition causes transformation to poorly differentiated gastric cancers.
Topics: Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasm Invasiveness; Protein Serine-Threonine Kinases; Stomach Neoplasms | 2022 |
Elevated expression of nuclear receptor-binding SET domain 3 promotes pancreatic cancer cell growth.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cohort Studies; CRISPR-Cas Systems; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice, Nude; Mutation; Neoplasm Invasiveness; Nuclear Proteins; Pancreatic Neoplasms; RNA, Messenger; RNA, Small Interfering; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2021 |
ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis.
Topics: Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; ets-Domain Protein Elk-4; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Receptor, Notch1; RNA, Long Noncoding; Stomach Neoplasms; Up-Regulation | 2021 |
TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.
Topics: Animals; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Demethylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Demethylases; Histones; Lung Neoplasms; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Protein Binding; Transcription Factors | 2021 |
Methylation Pattern Mediated by m
Topics: Adenocarcinoma of Lung; Humans; Lung Neoplasms; Methylation; Neoplasm Invasiveness; Prognosis; Transfection; Tumor Microenvironment | 2022 |
Knockdown of UCHL3 inhibits esophageal squamous cell carcinoma progression by reducing CRY2 methylation.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cryptochromes; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Ubiquitin Thiolesterase | 2022 |
MiR-6511b-5p suppresses metastasis of pMMR colorectal cancer through methylation of CD44 by directly targeting BRG1.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; DNA Helicases; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Methylation; MicroRNAs; Neoplasm Invasiveness; Nuclear Proteins; Transcription Factors | 2022 |
Circular RNA circSEPT9 Is Upregulated in Endometrial Cancer and Promotes Cell Invasion and Migration by Downregulating miR-186 through Methylation.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; RNA, Circular; Septins | 2022 |
MFAP2, upregulated by m1A methylation, promotes colorectal cancer invasiveness via CLK3.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Methylation; Mice; Mice, Nude; Microfibrils; Neoplasm Invasiveness; Proteins | 2023 |
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Topics: Acetylation; Animals; Azepines; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histocompatibility Antigens; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Snail Family Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta | 2019 |
LncRNA IUR downregulates ZEB1 by upregulating miR-200 to inhibit prostate carcinoma.
Topics: Adult; Aged; Cell Line, Tumor; Cell Movement; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Prostatic Neoplasms; RNA, Long Noncoding; Transfection; Up-Regulation; Zinc Finger E-box-Binding Homeobox 1 | 2019 |
RNA m
Topics: Adenosine; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epigenesis, Genetic; Gene Knockdown Techniques; Humans; Melanoma; Methylation; Methyltransferases; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; RNA, Messenger; RNA, Neoplasm; Up-Regulation; Uveal Neoplasms | 2020 |
Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer.
Topics: Animals; Cell Line, Tumor; Female; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Lymphangiogenesis; Methylation; Mice, Nude; Neoplasm Invasiveness; RNA, Long Noncoding; Transcriptional Activation; Triple Negative Breast Neoplasms | 2020 |
LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma.
Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HSP70 Heat-Shock Proteins; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proteasome Endopeptidase Complex; Proteolysis; RNA Stability; RNA, Long Noncoding; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Y-Box-Binding Protein 1 | 2020 |
DEP Domain Containing 1 Promotes Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Colorectal Cancer by Enhancing Expression of Suppressor of Zest 12.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; GTPase-Activating Proteins; Histones; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Transcription Factors; Up-Regulation | 2021 |
Histone Demethylase KDM7A Regulates Androgen Receptor Activity, and Its Chemical Inhibitor TC-E 5002 Overcomes Cisplatin-Resistance in Bladder Cancer Cells.
Topics: Aged; Aged, 80 and over; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Jumonji Domain-Containing Histone Demethylases; Male; Methylation; Mice, Inbred NOD; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; Receptors, Androgen; RNA, Messenger; Transcription, Genetic; Tumor Burden; Up-Regulation; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2020 |
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2.
Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms | 2020 |
HBXIP promotes gastric cancer
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Male; Methylation; Methyltransferases; Middle Aged; Neoplasm Invasiveness; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; RNA Processing, Post-Transcriptional; RNA, Messenger; Stomach Neoplasms | 2020 |
lncRNA DLGAP1-AS2 Knockdown Inhibits Hepatocellular Carcinoma Cell Migration and Invasion by Regulating miR-154-5p Methylation.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Cell Movement; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Humans; Liver Neoplasms; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Invasiveness; RNA, Long Noncoding; Survival Analysis; Up-Regulation | 2020 |
KIAA1429 promotes the progression of lung adenocarcinoma by regulating the m6A level of MUC3A.
Topics: A549 Cells; Adenocarcinoma of Lung; Adenosine; Cell Movement; Cell Proliferation; Databases, Genetic; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Methylation; Middle Aged; Mucin-3; Neoplasm Invasiveness; Neoplasm Staging; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; Signal Transduction; Tumor Burden | 2021 |
Long noncoding RNA ATB promotes ovarian cancer tumorigenesis by mediating histone H3 lysine 27 trimethylation through binding to EZH2.
Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Protein Binding; RNA, Long Noncoding; Treatment Outcome | 2021 |
Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Damage; DNA Repair; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; GPI-Linked Proteins; Heterografts; Humans; Male; Methylation; Mice; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Neuropeptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyrazines; Pyrazoles; TOR Serine-Threonine Kinases; Tumor Burden | 2021 |
Bioinformatic analyses and experimental validation of the role of m6A RNA methylation regulators in progression and prognosis of adrenocortical carcinoma.
Topics: Adenosine; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Computational Biology; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Immune Checkpoint Inhibitors; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nomograms; RNA; RNA-Binding Proteins; Survival Analysis; Survival Rate; Tumor Microenvironment | 2021 |
Arginine methyltransferase PRMT3 promote tumorigenesis through regulating c-MYC stabilization in colorectal cancer.
Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Neoplasm Invasiveness; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-myc; Ribosomal Proteins | 2021 |
m6A RNA methylation regulators were associated with the malignancy and prognosis of ovarian cancer.
Topics: Adenosine; Databases, Genetic; Female; Gene Regulatory Networks; Humans; Methylation; Neoplasm Invasiveness; Ovarian Neoplasms; Prognosis; RNA; Transcriptome | 2021 |
Immune infiltration-related N6-methyladenosine RNA methylation regulators influence the malignancy and prognosis of endometrial cancer.
Topics: Adenosine; Cell Line, Tumor; Cell Proliferation; Disease-Free Survival; DNA Copy Number Variations; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Ligands; Lymphocytes, Tumor-Infiltrating; Methylation; Middle Aged; Molecular Docking Simulation; Mutation; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Proportional Hazards Models; RNA, Messenger; Small Molecule Libraries; Tumor Microenvironment | 2021 |
Gα15 in early onset of pancreatic ductal adenocarcinoma.
Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; CRISPR-Cas Systems; Gene Expression; Gene Expression Regulation, Neoplastic; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; Methylation; Neoplasm Invasiveness; Pancreatic Neoplasms; Prognosis; Promoter Regions, Genetic; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2021 |
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay | 2021 |
Histone demethylase KDM4A plays an oncogenic role in nasopharyngeal carcinoma by promoting cell migration and invasion.
Topics: Adult; Aged; Animals; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Nude; Middle Aged; Nasopharyngeal Carcinoma; Neoplasm Invasiveness; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors; Up-Regulation; Young Adult | 2021 |
BORIS up-regulates OCT4 via histone methylation to promote cancer stem cell-like properties in human liver cancer cells.
Topics: Animals; Antibiotics, Antineoplastic; Binding Sites; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cell Self Renewal; DNA Methylation; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Methylation; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Octamer Transcription Factor-3; Phenotype; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; SOXB1 Transcription Factors; Thy-1 Antigens; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Long non-coding RNA CCAL promotes hepatocellular carcinoma progression by regulating AP-2α and Wnt/β-catenin pathway.
Topics: Acetylation; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Invasiveness; RNA, Long Noncoding; Transcription Factor AP-2; Wnt Signaling Pathway | 2018 |
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1 | 2018 |
Shikonin Inhibites Migration and Invasion of Thyroid Cancer Cells by Downregulating DNMT1.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; DNA (Cytosine-5-)-Methyltransferase 1; Dose-Response Relationship, Drug; Down-Regulation; Gene Amplification; Gene Knockdown Techniques; Humans; Methylation; Naphthoquinones; Neoplasm Invasiveness; PTEN Phosphohydrolase; RNA, Small Interfering; Thyroid Neoplasms | 2018 |
Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4.
Topics: Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Transcription Factors; Young Adult | 2018 |
Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Genes, Tumor Suppressor; HEK293 Cells; Humans; Male; Membrane Glycoproteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Microfilament Proteins; Neoplasm Invasiveness; Neoplasm Transplantation; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Transcription Factor AP-2; Transplantation, Heterologous; Tripartite Motif-Containing Protein 28; Zinc Fingers | 2018 |
Restoration of GATA4 expression impedes breast cancer progression by transcriptional repression of ReLA and inhibition of NF-κB signaling.
Topics: Antigens, CD; Apoptosis; Breast Neoplasms; Cadherins; Caspase 8; Cell Cycle; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Female; GATA4 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; MCF-7 Cells; Methylation; Neoplasm Invasiveness; NF-kappa B p50 Subunit; Phosphorylation; Promoter Regions, Genetic; Transcription Factor RelA; Transfection | 2019 |
LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment.
Topics: Animals; Base Sequence; Cell Line, Tumor; Chemokine CCL2; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Histones; Humans; Lymphangiogenesis; Lymphatic Metastasis; Lysine; Macrophages; Methylation; Mice; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Ribonucleoproteins; RNA, Long Noncoding; RNA, Neoplasm; Up-Regulation; Urinary Bladder Neoplasms | 2018 |
Downregulated long noncoding RNA LINC00313 inhibits the epithelial-mesenchymal transition, invasion, and migration of thyroid cancer cells through inhibiting the methylation of ALX4.
Topics: Animals; Cell Movement; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Male; Methylation; Mice; Mice, Nude; Neoplasm Invasiveness; RNA, Long Noncoding; Signal Transduction; Thyroid Neoplasms; Transcription Factors | 2019 |
LncRNA XIST facilitates cell growth, migration and invasion via modulating H3 histone methylation of DKK1 in neuroblastoma.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; HEK293 Cells; Heterografts; Histones; Humans; Intercellular Signaling Peptides and Proteins; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neuroblastoma; RNA, Long Noncoding; Transfection; Up-Regulation | 2019 |
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1.
Topics: AlkB Homolog 5, RNA Demethylase; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasm Invasiveness; RNA, Long Noncoding; Stomach Neoplasms | 2019 |
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Datasets as Topic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lung; Lung Neoplasms; Male; MAP Kinase Signaling System; Methylation; Methyltransferases; Middle Aged; Neoplasm Invasiveness; Pneumonectomy; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Survival Rate | 2019 |
Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer.
Topics: Animals; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Polycomb Repressive Complex 2; Receptors, Calcitriol; Recombinant Fusion Proteins; RNA Interference; Signal Transduction; STAT3 Transcription Factor | 2013 |
The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 2 Subunit; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; RNA Interference; RNA, Small Interfering | 2013 |
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.
Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation | 2013 |
microRNA-7 suppresses the invasive potential of breast cancer cells and sensitizes cells to DNA damages by targeting histone methyltransferase SET8.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Epithelial-Mesenchymal Transition; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; Neoplasm Proteins; RNA, Neoplasm | 2013 |
Expression of acetylated and dimethylated histone H3 in colorectal cancer.
Topics: Acetylation; Adenocarcinoma; Aged; Blotting, Western; Chromatin Immunoprecipitation; Colorectal Neoplasms; Female; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proportional Hazards Models | 2013 |
HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Embryo, Mammalian; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocyte Growth Factor; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms, Experimental; Male; Matrix Metalloproteinases, Secreted; Methylation; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Invasiveness; Neoplasm Transplantation; Promoter Regions, Genetic; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins c-met; Signal Transduction; Transcriptional Activation | 2013 |
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; Dual Specificity Phosphatase 3; Epigenesis, Genetic; F-Box Proteins; Female; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lung Neoplasms; Male; MAP Kinase Signaling System; Methylation; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA Interference; RNA, Messenger; RNA, Neoplasm | 2013 |
UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kaplan-Meier Estimate; Methylation; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Nuclear Proteins; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational | 2014 |
Effects of 5-azacytidine on RUNX3 gene expression and the biological behavior of esophageal carcinoma cells.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 3 Subunit; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Xenograft Model Antitumor Assays | 2014 |
Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
Topics: Acetylation; beta Catenin; Carcinoma, Hepatocellular; Fluorescent Antibody Technique; Hepatectomy; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Methylation; Multivariate Analysis; Neoplasm Invasiveness; Treatment Outcome; Tumor Suppressor Protein p53 | 2014 |
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition.
Topics: Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Methylation; Mixed Function Oxygenases; Neoplasm Invasiveness; Proto-Oncogene Proteins; RNA, Neoplasm; Time Factors; Transforming Growth Factor beta | 2014 |
Induction of the mesenchymal to epithelial transition by demethylation- activated microRNA-200c is involved in the anti-migration/invasion effects of arsenic trioxide on human breast cancer cells.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; Oxides; Up-Regulation | 2015 |
Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors.
Topics: Adult; Aged; Blood Vessels; Carcinoid Tumor; CpG Islands; Digestive System Neoplasms; Female; Gene Silencing; Humans; Ki-67 Antigen; Male; Methylation; Middle Aged; Mitotic Index; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Risk Factors; Sensitivity and Specificity; Ubiquitin Thiolesterase | 2014 |
Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease-Free Survival; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Methylation; Neoplasm Grading; Neoplasm Invasiveness; Receptor, ErbB-2; RNA Interference; RNA, Small Interfering | 2014 |
Comparative analysis of histone H3 and H4 post-translational modifications of esophageal squamous cell carcinoma with different invasive capabilities.
Topics: Acetylation; Carcinoma, Squamous Cell; Cell Line, Tumor; Esophageal Neoplasms; Histones; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Proteins; Protein Processing, Post-Translational | 2015 |
Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells.
Topics: beta Catenin; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 2; RNA Interference; Signal Transduction; Stomach Neoplasms; Time Factors; Transcription, Genetic; Transfection; Tyrosine | 2014 |
The differential localization of a methyl group confers a different anti-breast cancer activity to two triterpenes present in olives.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Female; Fruit; Humans; Methylation; Molecular Structure; Neoplasm Invasiveness; Olea; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species; Stereoisomerism; Triterpenes | 2015 |
[Effects of 5-aza-2-deoxycytidine on methylation status of RECK gene and cancer cell invasion in tongue cancer SCC-4 cells].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; GPI-Linked Proteins; Humans; Methylation; Neoplasm Invasiveness; RNA, Messenger; Tongue Neoplasms | 2014 |
DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Topics: Alternative Splicing; beta Catenin; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Neoplasm Invasiveness; RNA, Messenger; Up-Regulation | 2015 |
Epigenetic modifications in cutaneous malignant melanoma: EZH2, H3K4me2, and H3K27me3 immunohistochemical expression is enhanced at the invasion front of the tumor.
Topics: Adult; Aged; Biomarkers, Tumor; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Histones; Humans; Immunohistochemistry; Male; Melanoma; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplastic Stem Cells; Polycomb Repressive Complex 2; Predictive Value of Tests; Prognosis; Retrospective Studies; Skin Neoplasms | 2015 |
HPV infection and p16 promoter methylation as predictors of ASC-US/LSIL progression.
Topics: Adult; Biopsy, Needle; Cytodiagnosis; Disease Progression; Early Detection of Cancer; Female; Genes, p16; Humans; Immunohistochemistry; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Papillomavirus Infections; Predictive Value of Tests; Promoter Regions, Genetic; Retrospective Studies; Risk Assessment; Squamous Intraepithelial Lesions of the Cervix; Uterine Cervical Dysplasia | 2016 |
FAM98A is a novel substrate of PRMT1 required for tumor cell migration, invasion, and colony formation.
Topics: Animals; Cell Line, Tumor; Cell Movement; HEK293 Cells; Humans; Methylation; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Repressor Proteins | 2016 |
Upregulated SMYD3 promotes bladder cancer progression by targeting BCLAF1 and activating autophagy.
Topics: Aged; Autophagy; Carcinoma, Transitional Cell; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Histone Code; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Repressor Proteins; RNA Interference; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2016 |
NF-YA promotes invasion and angiogenesis by upregulating EZH2-STAT3 signaling in human melanoma cells.
Topics: CCAAT-Binding Factor; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Melanoma; Methylation; Neoplasm Invasiveness; Neovascularization, Pathologic; Signal Transduction; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2016 |
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Neoplasm Invasiveness; Neoplasms; Prognosis; Protein-Arginine N-Methyltransferases; Sequence Analysis, RNA; Transcription, Genetic; Transforming Growth Factor beta | 2017 |
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.
Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes | 2016 |
A New Chromatin-Cytoskeleton Link in Cancer.
Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin | 2016 |
Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Cytoskeletal Proteins; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; Histones; Humans; LIM Domain Proteins; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Transplantation, Heterologous | 2016 |
Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histones; Humans; Kaplan-Meier Estimate; Methylation; MicroRNAs; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; Transcription, Genetic; Urinary Bladder Neoplasms | 2017 |
Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.
Topics: Acetylation; Biomarkers, Tumor; Breast Neoplasms; Cluster Analysis; Female; Histones; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Methylation; Microarray Analysis; Neoplasm Invasiveness; Phenotype; Prognosis | 2009 |
Tumorigenic role of orphan nuclear receptor NR0B1 in lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Cell Line, Tumor; DAX-1 Orphan Nuclear Receptor; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphatic Metastasis; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; Prognosis; Promoter Regions, Genetic; Recurrence; Transcription, Genetic | 2009 |
Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.
Topics: Anticarcinogenic Agents; Arachidonic Acid; Breast Neoplasms; Cadherins; Cell Line, Tumor; Dietary Fats; DNA-Binding Proteins; Docosahexaenoic Acids; Down-Regulation; Eicosapentaenoic Acid; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Proteins; Linoleic Acid; Methylation; Neoplasm Invasiveness; Neoplasm Proteins; Polycomb Repressive Complex 2; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Transcription Factors | 2010 |
Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology.
Topics: Adenocarcinoma; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin A2; Cyclin-Dependent Kinase Inhibitor p21; Enzyme-Linked Immunosorbent Assay; Female; Genes, erbB-2; Histone Demethylases; Histones; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Progesterone; RNA Interference; RNA, Small Interfering | 2010 |
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Assembly and Disassembly; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Genome, Human; Histones; Humans; Methylation; Mice; Mice, Nude; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Polycomb-Group Proteins; Prognosis; Repressor Proteins; RNA Interference; RNA, Untranslated; Survival Rate | 2010 |
Deleted in Esophageal Cancer 1(DEC1) is down-regulated and contributes to migration in head and neck squamous cell carcinoma cell lines.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histones; Humans; Methylation; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Tumor Suppressor Proteins | 2011 |
Multi-cancer computational analysis reveals invasion-associated variant of desmoplastic reaction involving INHBA, THBS2 and COL11A1.
Topics: Collagen Type XI; Computational Biology; Fibroblasts; Humans; Inhibin-beta Subunits; Methylation; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Thrombospondins; Treatment Outcome | 2010 |
Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Azacitidine; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Shape; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Esophageal Neoplasms; Female; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Transcription, Genetic | 2011 |
Global histone H4K20 trimethylation predicts cancer-specific survival in patients with muscle-invasive bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Female; Histones; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Prognosis; Survival Rate; Urinary Bladder Neoplasms | 2011 |
SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9.
Topics: Animals; Blotting, Western; Cattle; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Host-Parasite Interactions; Humans; Matrix Metalloproteinase 9; Methylation; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Theileria; Theileriasis; Transplantation, Heterologous; Up-Regulation; Zebrafish | 2012 |
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Mice, Inbred ICR; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasm Transplantation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Snail Family Transcription Factors; Transcription Factors | 2012 |
The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer.
Topics: Cell Line, Tumor; Cell Movement; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Neoplasm Invasiveness; Nuclear Proteins; Prostatic Neoplasms; Protein Binding; Protein Processing, Post-Translational; Repressor Proteins; RNA, Small Interfering; Twist-Related Protein 1 | 2013 |
The regulatory mechanism of the LY6K gene expression in human breast cancer cells.
Topics: Antigens, Ly; Binding Sites; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factor AP-1 | 2012 |
CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Cullin Proteins; Cyclin-Dependent Kinase Inhibitor p16; DNA-Binding Proteins; Esophageal Neoplasms; Female; Histones; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Polycomb Repressive Complex 2; PTEN Phosphohydrolase; Transcription, Genetic; Transplantation, Heterologous; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation | 2012 |
Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers.
Topics: Adult; Base Sequence; Breast Neoplasms; Carcinoma, Ductal, Breast; DNA Copy Number Variations; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Middle Aged; Mutation; Neoplasm Invasiveness; Nuclear Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2013 |
Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinases; Methylation; Neoplasm Invasiveness; Pancreatic Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Expression of carbonic anhydrase 9 at the invasion front of gastric cancers.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Western; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Proliferation; Female; Humans; Isoenzymes; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Stomach Neoplasms; Transfection; Tumor Cells, Cultured | 2005 |
Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Carrier Proteins; Colorectal Neoplasms; Disease Progression; Female; Humans; Male; Methylation; Microsatellite Repeats; Middle Aged; MutL Protein Homolog 1; Neoplasm Invasiveness; Neoplasm Staging; Nuclear Proteins; Promoter Regions, Genetic | 2005 |
A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.
Topics: Animals; Cell Line; Chlorocebus aethiops; CpG Islands; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Melanoma; Methylation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Neoplastic Stem Cells; Promoter Regions, Genetic; Proto-Oncogene Proteins c-met; RNA, Messenger; Snail Family Transcription Factors; Transcription Factor AP-2; Transcription Factors; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2006 |
Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; CpG Islands; Epithelial Cells; Humans; Intestinal Mucosa; Methylation; Microsatellite Instability; Models, Biological; Mutation; MutL Protein Homolog 1; Neoplasm Invasiveness; Neoplasm Proteins; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf | 2007 |
Relationship between expression and methylation status of p16INK4a and the proliferative activity of different areas' tumour cells in human colorectal cancer.
Topics: Adolescent; Adult; Aged; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Female; Gene Expression; Genes, p16; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging | 2007 |
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.
Topics: Azacitidine; Base Sequence; Cadherins; Carcinoma; DNA Primers; DNA, Neoplasm; Gene Expression; Genes, Regulator; Genes, Tumor Suppressor; Humans; Methylation; Molecular Sequence Data; Neoplasm Invasiveness; Oligodeoxyribonucleotides; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1995 |
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
Topics: Administration, Oral; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Deoxyguanosine; Disease Progression; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Injections, Intraperitoneal; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1994 |
Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines.
Topics: Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Transitional Cell; CpG Islands; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Kangai-1 Protein; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Neoplasm Invasiveness; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2000 |
Effects of methylthiodeoxyadenosine and its analogs on in vitro invasion of rat ascites hepatoma cells and methylation of their phospholipids.
Topics: Animals; Cell Division; Cell Membrane; Deoxyadenosines; In Vitro Techniques; Liver Neoplasms, Experimental; Membrane Fluidity; Membrane Lipids; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Phospholipids; Thionucleosides; Thionucleotides; Tumor Cells, Cultured | 1991 |
Inhibition of in vitro tumor cell invasion by transmethylation inhibitors.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Deoxyadenosines; Fibrosarcoma; Humans; Kinetics; Liver Neoplasms, Experimental; Lung Neoplasms; Melanoma, Experimental; Methylation; Neoplasm Invasiveness; Rats; Rats, Inbred Strains; Thionucleosides; Tumor Cells, Cultured | 1989 |
Differential hypomethylation of the c-myc protooncogene in bladder cancers at different stages and grades.
Topics: 5-Methylcytosine; Autoradiography; Blotting, Southern; Carcinoma, Transitional Cell; Cytosine; DNA, Neoplasm; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Staging; Oncogenes; Prognosis; Proto-Oncogene Mas; Proto-Oncogenes; Urinary Bladder Neoplasms | 1989 |