Page last updated: 2024-08-18

isomethyleugenol and Idiopathic Parkinson Disease

isomethyleugenol has been researched along with Idiopathic Parkinson Disease in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199016 (27.59)18.7374
1990's18 (31.03)18.2507
2000's12 (20.69)29.6817
2010's9 (15.52)24.3611
2020's3 (5.17)2.80

Authors

AuthorsStudies
Francis, P; Geut, H; Hannon, E; Henriksen, SP; Love, S; Mill, J; Pihlstrøm, L; Rozemuller, AJM; Shireby, G; Thomas, AJ; Toft, M; Tunold, JA; van de Berg, WDJ1
Iga, JI; Nagai, M; Nomoto, M; Ochi, S; Ozaki, Y; Ueno, SI; Yamazaki, K; Yoshino, Y1
Basavarajappa, BS; Subbanna, S1
Neal, M; Richardson, JR1
Burbulla, LF; Jeon, S; Jiang, W; Krainc, D; Oevel, K; Silverman, RB; Ysselstein, D; Zheng, J1
Ali, S; Chen, X; Guo, M; Huang, H; Huang, Y; Qie, S; Wang, J; Wang, S; Yu, C; Zhang, L; Zheng, X1
Chen, C; Guo, J; Min, S; Pan, H; Qin, L; Shu, L; Sun, Q; Tang, B; Xu, Q; Yan, X; Zhong, J1
Jadavji, NM; Murray, LK1
Monti, B; Peña-Altamira, LE; Polazzi, E1
Bolt, EL; Carter, WG; Cass, S; Ray, DE; Vigneswara, V; Wayne, D1
Calzada, E; Claypool, SM; Onguka, O1
Bouchard, TP; Camicioli, RM; Somerville, MJ1
Dillmann, U; Fassbender, K; Herrmann, W; Kostopoulos, P; Obeid, R; Schadt, A1
Barone, P; De Bonis, ML; Galletti, P; Ingrosso, D; Longo, K; Pellecchia, MT; Russo, A; Salvatore, A; Tedeschi, G; Tessitore, A; Zappia, V1
Mattson, MP; Shea, TB1
Decker, PA; Dousa, MK; Muenter, MD; Offord, KP; Tyce, GM; Weinshilboum, RM1
Steventon, GB; Waring, RH; Williams, AC1
Di Rocco, A; Werner, P1
Brosnan, JT; Brosnan, ME; Jacobs, RL; Stead, LM1
Ramsden, DB; Williams, AC2
Awad, L; Benavides, J; Camelin, JC; Gauthier, A; Laquais, B; Lefur, G; Meininger, V; Mizoule, J; Phan, T; Uzan, A1
Lewis, ME1
Bottiglieri, T; Hyland, K; Reynolds, EH1
Dostert, P; Maruyama, W; Matsubara, K; Naoi, M1
Green, S; Peters, L; Steventon, GB; Sturman, S; Waring, RH; Williams, AC1
Maruyama, W; Nagatsu, T; Naoi, M; Niwa, T1
Cobuzzi, RJ; Collins, MA; Neafsey, EJ1
Buttrum, S; Green, S; Molloy, H; Pall, HS; Steventon, GB; Waring, RH; Williams, AC1
Dostert, P; Nagatsu, T; Naoi, M; Yoshida, M1
Männistö, PT; Reenilä, I; Tuomainen, P1
Charlton, CG; Crowell, B1
Hattori, T; Kondo, T; Mizuno, Y; Nakagawa-Hattori, Y1
Collins, MA; Gearhart, DA; Neafsey, EJ1
Hoffman, RM1
Häussermann, P; Kuhn, W; Müller, T; Przuntek, H; Rommelspacher, H; Sällström Baum, S; Woitalla, D1
Aoyama, K; Fukushima, S; Hayase, N; Kobayashi, S; Matsubara, K; Ohta, S; Okada, K; Satomi, M; Shimizu, K; Shiono, H; Uezono, T; Yamaguchi, S1
Steventon, GB; Sturman, S; Waring, RH; Williams, AC1
Zhu, BT1
Fremouw-Ottevangers, DC; Gerding, AM; Muskiet, FA; Nagel, GT; Thomasson, CG; Wolthers, BG1
Muenter, MD; Sharpless, NS; Tyce, GM1
Dostert, P; Maruyama, W; Nagatsu, T; Nakahara, D; Naoi, M; Niwa, T; Takahashi, A; Takeda, N; Tatematsu, A; Yoshizumi, H1
Roth, JA1
Albores, R; Cobuzzi, R; Collins, MA; Fields, J; Matsubara, K; Neafsey, EJ; Rollema, H1
Buttrum, S; Green, S; Molloy, H; Pall, H; Steventon, G; Sturman, S; Waring, R; Williams, A1
Steventon, G; Sturman, S; Waring, R; Williams, A1
Costall, B; Jenner, P; Marsden, CD; Naylor, R; Testa, B1
Hirose, S; Ishimitsu, T1
Chase, TN; Woods, AC1
Hartley, R; Smith, JA1
Barrass, BC; Coult, DB; Pinder, RM1
Ceccato, S; Passeri, M1
Sandler, M1
Brossi, A; Teitel, S1
Bohuon, C; Comoy, E; Lhermitte, F; Rosa, A1
Goodwin, FK1
Cotzias, GC1
Radouco-Thomas, S1

Reviews

18 review(s) available for isomethyleugenol and Idiopathic Parkinson Disease

ArticleYear
Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology.
    Nature communications, 2022, 08-22, Volume: 13, Issue:1

    Topics: alpha-Synuclein; Epigenome; Frontal Lobe; Humans; Lewy Bodies; Lewy Body Disease; Methylation; Parkinson Disease

2022
Histone Methylation Regulation in Neurodegenerative Disorders.
    International journal of molecular sciences, 2021, Apr-28, Volume: 22, Issue:9

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Epigenesis, Genetic; Histone Code; Histones; Humans; Huntington Disease; Methylation; Neurodegenerative Diseases; Parkinson Disease; Protein Processing, Post-Translational; Substance-Related Disorders

2021
Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:2

    Topics: Acetylation; Alzheimer Disease; Animals; Astrocytes; Cell Differentiation; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Inflammation; Methylation; MicroRNAs; Neurodegenerative Diseases; Neuroglia; Neurons; Parkinson Disease

2018
The role of one-carbon metabolism and homocysteine in Parkinson's disease onset, pathology and mechanisms.
    Nutrition research reviews, 2019, Volume: 32, Issue:2

    Topics: Animals; Diet; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Levodopa; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Nutritional Status; One-Carbon Group Transferases; Parkinson Disease; Polymorphism, Genetic; Vitamin B Complex

2019
Histone post-translational modifications in Huntington's and Parkinson's diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Humans; Huntington Disease; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination

2013
Phosphatidylethanolamine Metabolism in Health and Disease.
    International review of cell and molecular biology, 2016, Volume: 321

    Topics: Alzheimer Disease; Animals; Autophagy; Candida; Carboxy-Lyases; Cell Membrane; Cytidine Diphosphate; Ethanolamines; Humans; Lipid Metabolism; Methylation; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidative Phosphorylation; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Prions; Protein Processing, Post-Translational; Virulence

2016
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
Methylation demand: a key determinant of homocysteine metabolism.
    Acta biochimica Polonica, 2004, Volume: 51, Issue:2

    Topics: Animals; Creatine; Guanidinoacetate N-Methyltransferase; Homocysteine; Humans; Levodopa; Methylation; Methyltransferases; Models, Biological; Models, Chemical; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats

2004
Autotoxicity, methylation and a road to the prevention of Parkinson's disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2005, Volume: 12, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine Agents; Humans; Methylation; Niacinamide; Parkinson Disease; Parkinson Disease, Secondary; Risk Factors; S-Adenosylmethionine

2005
Biochemical aspects of schizophrenia.
    Essays in neurochemistry and neuropharmacology, 1980, Volume: 4

    Topics: Amphetamines; Animals; Antipsychotic Agents; Brain; Catecholamines; Dopamine; Humans; Indoles; Mesencephalon; Methionine; Methylation; Monoamine Oxidase; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Schizophrenia

1980
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
    Drugs, 1994, Volume: 48, Issue:2

    Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases

1994
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease.
    Human cell, 1997, Volume: 10, Issue:1

    Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins

1997
A review of xenobiotic metabolism enzymes in Parkinson's disease and motor neuron disease.
    Drug metabolism and drug interactions, 2001, Volume: 18, Issue:2

    Topics: Adult; Aged; Carbocysteine; Case-Control Studies; Expectorants; Humans; Methylation; Methyltransferases; Middle Aged; Monoamine Oxidase; Motor Neuron Disease; Odds Ratio; Oxidation-Reduction; Parkinson Disease; Phenotype; Statistics, Nonparametric; Substrate Specificity; Xenobiotics

2001
Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: importance in pathophysiology and pathogenesis.
    Current drug metabolism, 2002, Volume: 3, Issue:3

    Topics: Animals; Catechol O-Methyltransferase; Catecholamines; Catechols; Dopamine; Enzyme Inhibitors; Estrogens; Humans; Kinetics; Methylation; Neoplasms; Parkinson Disease; Plant Preparations; Polymorphism, Genetic; Xenobiotics

2002
Membrane-bound catechol-O-methyltransferase: a reevaluation of its role in the O-methylation of the catecholamine neurotransmitters.
    Reviews of physiology, biochemistry and pharmacology, 1992, Volume: 120

    Topics: Animals; Antidepressive Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cell Membrane; Gene Expression Regulation, Enzymologic; Humans; Membrane Proteins; Methylation; Parkinson Disease

1992
L-dopa metabolism in man (with special reference to parkinsonism).
    The Scientific basis of medicine annual reviews, 1972

    Topics: Catecholamines; Dihydroxyphenylalanine; Dopamine; Humans; Hydroxylation; Methylation; Norepinephrine; Parkinson Disease; Schiff Bases

1972
Alkaloids in the mammalian system.
    Lloydia, 1974, Volume: 37, Issue:2

    Topics: 5-Hydroxytryptophan; Acetaldehyde; Alkaloids; Animals; Aporphines; Biogenic Amines; Catalysis; Cells, Cultured; Circular Dichroism; Cyclization; Dealkylation; Dihydroxyphenylalanine; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Mammals; Methylation; Molecular Conformation; Parkinson Disease; Stereoisomerism; Tryptophan

1974
Psychiatric side effects of levodopa in man.
    JAMA, 1971, Dec-27, Volume: 218, Issue:13

    Topics: Animals; Brain; Catecholamines; Cognition Disorders; Delirium; Depression; Dihydroxyphenylalanine; Dopamine; Female; Haplorhini; Humans; Hyperkinesis; Male; Methylation; Methyltyrosines; Parkinson Disease; Psychoses, Substance-Induced; Rats; Sexual Behavior; Time Factors

1971

Trials

2 trial(s) available for isomethyleugenol and Idiopathic Parkinson Disease

ArticleYear
Plasma levels of R- and S-salsolinol are not increased in "de-novo" Parkinsonian patients.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Dopamine; Female; Humans; Isoquinolines; Male; Methylation; Middle Aged; Parkinson Disease; Stereoisomerism

1998
N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: Aged; Aging; Aldehyde Oxidase; Aldehyde Oxidoreductases; Brain; Carbolines; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Humans; Isoquinolines; Male; Methylation; Middle Aged; Niacinamide; Parkinson Disease

2000

Other Studies

38 other study(ies) available for isomethyleugenol and Idiopathic Parkinson Disease

ArticleYear
DRD2 methylation to differentiate dementia with Lewy bodies from Parkinson's disease.
    Acta neurologica Scandinavica, 2020, Volume: 141, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Diagnosis, Differential; Female; Humans; Leukocytes; Lewy Body Disease; Male; Methylation; Parkinson Disease; Receptors, Dopamine D2

2020
Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Dopaminergic Neurons; Enzyme Activators; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Humans; Methylation; Parkinson Disease; Quinazolines; Structure-Activity Relationship

2019
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death.
    ACS chemical neuroscience, 2019, 05-15, Volume: 10, Issue:5

    Topics: Adenosine; Animals; Apoptosis; Brain; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Epigenesis, Genetic; Male; Methylation; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympatholytics

2019
Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson's disease.
    Neurobiology of aging, 2019, Volume: 84

    Topics: DNA Methylation; Humans; Methylation; Parkinson Disease

2019
Molecular ageing of alpha- and Beta-synucleins: protein damage and repair mechanisms.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: alpha-Synuclein; Amino Acid Sequence; Animals; beta-Synuclein; Brain; Chromatography, Gel; Cytoplasm; Humans; Isoaspartic Acid; Isoelectric Point; Methylation; Mice; Mice, Knockout; Molecular Sequence Data; Mutation, Missense; Parkinson Disease; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Sequence Homology, Amino Acid

2013
Homocysteine is not associated with global motor or cognitive measures in nondemented older Parkinson's disease patients.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jan-30, Volume: 24, Issue:2

    Topics: Aged; Antiparkinson Agents; Cognition; Creatinine; Female; Folic Acid; Genotype; Homocysteine; Humans; Inactivation, Metabolic; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Motor Skills; Neuropsychological Tests; Parkinson Disease; Severity of Illness Index; Vitamin B Complex

2009
Methylation status and neurodegenerative markers in Parkinson disease.
    Clinical chemistry, 2009, Volume: 55, Issue:10

    Topics: Aged; alpha-Synuclein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Biomarkers; Blood Platelets; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Methylation; Middle Aged; Nerve Degeneration; Parkinson Disease; Peptide Fragments; S-Adenosylhomocysteine; S-Adenosylmethionine; Substantia Nigra; Ultrasonography; Vitamin B 6

2009
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
    Neuroscience letters, 2010, Jan-14, Volume: 468, Issue:3

    Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine

2010
L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:8

    Topics: Adenosine Diphosphate; Aged; Arylsulfotransferase; Biotransformation; Blood Platelets; Carbidopa; Catechol O-Methyltransferase; Dose-Response Relationship, Drug; Drug Combinations; Erythrocytes; Female; Humans; Levodopa; Male; Methylation; Middle Aged; Parkinson Disease; S-Adenosylmethionine; Sulfates

2003
An investigation into the inter-relationships of sulphur xeno-biotransformation pathways in Parkinson's and motor neurone diseases.
    Drug metabolism and drug interactions, 2003, Volume: 19, Issue:4

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Biotransformation; Carbocysteine; Erythrocytes; Female; Humans; Male; Methylation; Methyltransferases; Middle Aged; Motor Neuron Disease; Oxidation-Reduction; Parkinson Disease; Phenotype; Sulfur

2003
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status.
    Neurology, 2004, Feb-24, Volume: 62, Issue:4

    Topics: Antiparkinson Agents; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Methylation; Parkinson Disease; S-Adenosylmethionine; Vitamin B Complex

2004
Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases.
    Medical hypotheses, 2005, Volume: 65, Issue:2

    Topics: Animals; Choline; Embryonic Development; Epigenesis, Genetic; Evolution, Molecular; Homeostasis; Humans; Methylation; Models, Theoretical; Niacinamide; Parkinson Disease; Xenobiotics

2005
[Methylation of erythrocyte membrane phospholipids: correlation with membrane viscosity. Study of normal and parkinsonian subjects].
    Revue neurologique, 1984, Volume: 140, Issue:8-9

    Topics: Adolescent; Adult; Aged; Blood Viscosity; Erythrocyte Membrane; Female; Humans; Kinetics; Male; Membrane Fluidity; Membrane Lipids; Methylation; Middle Aged; Osmotic Fragility; Parkinson Disease; Phospholipids; Receptors, Neurotransmitter

1984
N-methyl(R)salsolinol produces hydroxyl radicals: involvement to neurotoxicity.
    Free radical biology & medicine, 1995, Volume: 19, Issue:1

    Topics: Animals; Ascorbic Acid; Catalase; Chromatography, High Pressure Liquid; Dopamine; Ferric Compounds; Ferrous Compounds; Free Radicals; Glutathione; Humans; Hydroxyl Radical; Isoquinolines; Methylation; Neurons; Oxidation-Reduction; Parkinson Disease; Salsoline Alkaloids; Superoxide Dismutase; Tetrahydroisoquinolines

1995
D-penicillamine metabolism in neurodegenerative diseases: an in vivo/in vitro sulphydryl methylation study.
    Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Erythrocyte Membrane; Female; Humans; Male; Methylation; Methyltransferases; Middle Aged; Motor Neuron Disease; Parkinson Disease; Penicillamine; Sulfhydryl Compounds

1994
Novel toxins and Parkinson's disease: N-methylation and oxidation as metabolic bioactivation of neurotoxin.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Adenosine Triphosphate; Animals; Brain; Cell Count; Humans; Isoquinolines; Methylation; Microdialysis; Neurotoxins; Oxidation-Reduction; Parkinson Disease; PC12 Cells; Rats; Tissue Distribution

1994
Differential cytotoxicities of N-methyl-beta-carbolinium analogues of MPP+ in PC12 cells: insights into potential neurotoxicants in Parkinson's disease.
    Journal of neurochemistry, 1994, Volume: 62, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cations; Cell Death; Culture Media; Energy Metabolism; Harmaline; Kinetics; L-Lactate Dehydrogenase; Methylation; Molecular Structure; Parkinson Disease; PC12 Cells; Rats

1994
N-methylation of pyridines and Parkinson's disease.
    Advances in neurology, 1993, Volume: 60

    Topics: Humans; Methylation; Methyltransferases; Niacinamide; Parkinson Disease; Pyridines; Pyridones

1993
N-methylated tetrahydroisoquinolines as dopaminergic neurotoxins.
    Advances in neurology, 1993, Volume: 60

    Topics: Animals; Brain; Cell Death; Culture Techniques; Dopamine; Humans; Isoquinolines; Methylation; Methyltransferases; Monoamine Oxidase; Nerve Degeneration; Parkinson Disease; Rats; Receptors, Dopamine; Substantia Nigra; Tetrahydroisoquinolines

1993
Validation of assay of catechol-O-methyltransferase activity in human erythrocytes.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:5

    Topics: Blood Proteins; Catechol O-Methyltransferase; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; Enzyme Inhibitors; Enzyme Stability; Erythrocytes; Humans; Methylation; Nitriles; Parkinson Disease; Reproducibility of Results; Sensitivity and Specificity

1996
Striatal dopamine depletion, tremors, and hypokinesia following the intracranial injection of S-adenosylmethionine: a possible role of hypermethylation in parkinsonism.
    Molecular and chemical neuropathology, 1995, Volume: 26, Issue:3

    Topics: Animals; Antiparkinson Agents; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Hypokinesia; Injections, Intraventricular; Levodopa; Male; Methylation; Motor Activity; Neostriatum; Parkinson Disease; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tremor

1995
S-methylation in Parkinson's disease.
    Neurology, 1995, Volume: 45, Issue:12

    Topics: Aged; Erythrocyte Membrane; Female; Humans; Male; Methylation; Methyltransferases; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Reference Values; Sulfhydryl Compounds

1995
Characterization of brain beta-carboline-2-N-methyltransferase, an enzyme that may play a role in idiopathic Parkinson's disease.
    Neurochemical research, 1997, Volume: 22, Issue:2

    Topics: Animals; Brain; Carbolines; Cattle; Cytosol; Enzyme Inhibitors; Harmine; Humans; Hydrogen-Ion Concentration; Kinetics; Methylation; Methyltransferases; Parkinson Disease; S-Adenosylhomocysteine; S-Adenosylmethionine; Zinc

1997
Determination of catecholamines and their 3-O-methylated metabolites in urine by mass fragmentography with use of deuterated internal standards.
    Clinical chemistry, 1979, Volume: 25, Issue:3

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Catecholamines; Child; Child, Preschool; Deuterium; Dopamine; Epinephrine; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Methylation; Middle Aged; Neuroblastoma; Norepinephrine; Parkinson Disease; Pheochromocytoma; Reference Values

1979
Effect of L-DOPA on endogenous histamine metabolism.
    Medical biology, 1975, Volume: 53, Issue:2

    Topics: Acetates; Adult; Aged; Animals; Carbidopa; Depression, Chemical; Female; Guinea Pigs; Histamine; Humans; Imidazoles; Levodopa; Male; Methylation; Middle Aged; Parkinson Disease; Rats; Species Specificity

1975
Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry.
    Journal of chromatography, 1992, Jul-01, Volume: 578, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Gas Chromatography-Mass Spectrometry; Isoquinolines; Male; Methylation; Parkinson Disease; Perfusion; Rats; Rats, Wistar; Salsoline Alkaloids; Tetrahydroisoquinolines

1992
Indole-N-methylation of beta-carbolines: the brain's bioactivation route to toxins in Parkinson's disease?
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: Animals; Biotransformation; Brain; Carbolines; Humans; Methylation; Mitochondria; Neurotoxins; Parkinson Disease; Rats

1992
N-methylation of pyridines in Parkinson's disease.
    Lancet (London, England), 1991, Jul-13, Volume: 338, Issue:8759

    Topics: Humans; Methylation; Middle Aged; Niacinamide; Parkinson Disease

1991
Xenobiotic enzyme profiles and Parkinson's disease.
    Neurology, 1991, Volume: 41, Issue:5 Suppl 2

    Topics: Animals; Humans; Methylation; Methyltransferases; Monoamine Oxidase; MPTP Poisoning; Parkinson Disease; Sulfur; Xenobiotics

1991
Does an endogenous methylpyridinium analogue cause Parkinson's disease?
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Chemical Phenomena; Chemistry; Humans; Methylation; Parkinson Disease; Pyridines

1985
Determination of m- and p-O-methylated products of L-3,4-dihydroxyphenylalanine using high-performance liquid chromatography and electrochemical detection.
    Analytical biochemistry, 1985, Nov-01, Volume: 150, Issue:2

    Topics: Animals; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Isomerism; Levodopa; Liver; Methylation; Parkinson Disease; Rats; Rats, Inbred Strains; Tyrosine

1985
M.I.F.: effect on levodopa dyskinesias in man.
    Lancet (London, England), 1973, Sep-01, Volume: 2, Issue:7827

    Topics: Antiparkinson Agents; Carbidopa; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Humans; Melanocyte-Stimulating Hormones; Methylation; Movement Disorders; Parkinson Disease

1973
Abnormal O-methylated dopamine metabolites: the endogenous toxins of schizophrenia or parkinsonism?
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:5

    Topics: Animals; Behavior, Animal; Hallucinogens; Humans; Methylation; Parkinson Disease; Phenethylamines; Schizophrenia; Toxins, Biological

1973
3-Hydroxy-4-methoxyphenethylamine: the endogenous toxin of parkinsonism?
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:6

    Topics: Catechol O-Methyltransferase Inhibitors; Ceruloplasmin; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Humans; Methylation; Parkinson Disease; Phenethylamines; Protein Binding

1972
[Significance of transmethylation and S-adenosylmethionine (SAM) in the management of Parkinson's disease with L-dopa].
    Minerva medica, 1972, Apr-21, Volume: 63, Issue:30

    Topics: Adenosine; Aged; Brain; Digestive System; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney; Male; Methionine; Methylation; Nausea; Parkinson Disease; S-Adenosylmethionine; Vomiting

1972
[Abnormal movements induced by L-Dopa and dopamine metabolism disorders].
    Revue neurologique, 1973, Volume: 129, Issue:6

    Topics: Benzoates; Dihydroxyphenylalanine; Dopamine; Electrocoagulation; Female; Homovanillic Acid; Humans; Methylation; Middle Aged; Movement Disorders; Parkinson Disease

1973
Levodopa in the treatment of Parkinsonism.
    JAMA, 1971, Dec-27, Volume: 218, Issue:13

    Topics: Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; Dopamine; Esters; Humans; Hydrazines; Manganese Poisoning; Methylation; Methyldopa; Mice; Movement; Parkinson Disease; Parkinson Disease, Secondary; Phenylacetates

1971
[Extrapyramidal syndrome in animal experiments: rôle of calcium and o-methylated derivatives].
    Laval medical, 1970, Volume: 41, Issue:7

    Topics: Animals; Calcium; Calcium Metabolism Disorders; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tracts; Guinea Pigs; Hydrogen-Ion Concentration; Methylation; Movement Disorders; Norepinephrine; Parkinson Disease; Pyrogallol; Rats; Reserpine; Serotonin Antagonists; Stimulation, Chemical; Synapses; Tranylcypromine

1970