Page last updated: 2024-08-18

isomethyleugenol and Huntington Disease

isomethyleugenol has been researched along with Huntington Disease in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's8 (23.53)18.2507
2000's5 (14.71)29.6817
2010's12 (35.29)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Chighladze, E; Cole, RN; Faragó, A; Jiang, M; Jin, J; Kamath, SV; O'Meally, RN; Ratovitski, T; Rauniyar, P; Ross, CA; Shevelkin, AV1
Gordevičius, J; Graham, SF; Green, BD; Kerševičiūte, I; Khalid, A; Koladiya, PR; Macias, S; Mann, D; Pan, X; Radhakrishna, U; Robinson, AC; Saiyed, N; Vishweswaraiah, S; Yilmaz, A1
Anderson, EN; Basso, M; Caricasole, A; Grant, RA; Hernández, IH; Lucas, JJ; Migazzi, A; Pandey, UB; Pennuto, M; Ratovitski, T; Roccuzzo, M; Ross, CA; Saudou, F; Scaramuzzino, C; Tosatto, L; Tripathy, D; Virlogeux, A; Zuccato, C1
Basavarajappa, BS; Subbanna, S1
Bassi, S; Biagioli, M; Di Leva, F; Monziani, A; Tripathi, T1
Hu, W; Lin, X; Zhang, H; Zhao, N1
Bodai, L; Faragó, A; Marsh, JL; Song, W; Zsindely, N1
Monti, B; Peña-Altamira, LE; Polazzi, E1
Bates, GP; Bodai, L; Finkbeiner, S; Fraenkel, E; Gipson, TA; Housman, DE; Krainc, D; Kratter, IH; Labadorf, A; Lau, A; Marsh, JL; Ng, CW; Ross, CA; Sadri-Vakili, G; Song, W; Thompson, LM; Troncosco, J; Vashishtha, M; Vogel-Ciernia, A; Yildirim, F1
Hwang, YJ; Kowall, NW; Lee, J; Ryu, H1
Han, D; Hwang, YJ; Kim, KY; Kim, Y; Kowall, NW; Lee, J; Min, SJ; Ryu, H; Yang, L1
Fischhaber, PL; Guo, C; Tang, TS; Wang, F1
Di Stefano, L; Dietz, KN; Gusella, JF; Macdonald, ME; Maher, RC; Walker, JA; Zhu, H1
Derryberry, J; Hawk, AJ; Lanning, JD; Meredith, SC1
Cho, KS; Hong, YK; Hwang, YJ; Jeon, GS; Jung, MK; Kim, KY; Kowall, NW; Lee, J; Picketts, DJ; Ryu, H; Seong, KH1
Chan, JP; Festenstein, R; Goula, AV; Merienne, K; Stys, A; Trottier, Y1
Beal, MF; Browne, SE; Choi, DK; Ferrante, RJ; Gardian, G; Gregorio, J; Klivenyi, P; Kubilus, JK; Langley, B; Ratan, RR; Ryu, H1
Beal, MF; Browne, S; D'Mello, S; Ferrante, RJ; Hewett, S; Kristal, BS; Kubilus, JK; Langley, B; Lee, J; Lu, P; Ratan, RR; Rubinsztein, DC; Ryu, H; Smith, K; Stavrovskaya, IG; Sugars, KL1
Cormier, KA; Ferrante, RJ; Hagerty, SW; Lee, J; McAlpin, SE; Ryu, H; Smith, KM; Soh, BY1
Cormier, K; Del Signore, SJ; Ferrante, RJ; Goldstein, DR; Goodrich, S; Hagerty, SW; Luthi-Carter, R; Markey, AL; Matson, S; Ryu, H; Smith, K; Soh, BY; Stack, EC1
Cha, JH; Chawla, P; Kim, MO; Overland, RP; Sadri-Vakili, G; Xia, E1
Bates, G; Lehrach, H1
Harding, AE; Maher, ER; Morrison, PJ; Reik, W; Simpson, SA1
Carlock, L; Lorincz, M; Pandrangi, A; Vo, T; Wisniewski, D1
Conneally, PM; Cupples, LA; Farrer, LA; Kiely, DK; Myers, RH1
Conneally, PM; Farrer, LA; Frith, CD; Ridley, RM1
Collins, C; Hayden, MR; Kowbel, D; Riess, O; Weber, B1
Sapienza, C1
Laird, CD1
Ferluga, J1
Cox, DR; Myers, RM; Pritchard, CA1
Hayden, MR; Robbins, CA; Theilmann, JL1
Conneally, PM; Crow, TJ; Frith, CD; Ridley, RM1
Reik, W1

Reviews

6 review(s) available for isomethyleugenol and Huntington Disease

ArticleYear
Histone Methylation Regulation in Neurodegenerative Disorders.
    International journal of molecular sciences, 2021, Apr-28, Volume: 22, Issue:9

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Epigenesis, Genetic; Histone Code; Histones; Humans; Huntington Disease; Methylation; Neurodegenerative Diseases; Parkinson Disease; Protein Processing, Post-Translational; Substance-Related Disorders

2021
Epigenetics of Huntington's Disease.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Animals; Cell Line; Chromatin Assembly and Disassembly; Clinical Trials as Topic; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Methylation; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Polycomb-Group Proteins; Protein Processing, Post-Translational; RNA, Untranslated

2017
Histone post-translational modifications in Huntington's and Parkinson's diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Humans; Huntington Disease; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination

2013
Nucleolar dysfunction in Huntington's disease.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:6

    Topics: Acetylation; Cell Nucleolus; Epigenesis, Genetic; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mutation; Nerve Tissue Proteins; Neurons; Pol1 Transcription Initiation Complex Proteins; Trinucleotide Repeat Expansion

2014
Trinucleotide repeat expansions and human genetic disease.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1994, Volume: 16, Issue:4

    Topics: Adult; Age of Onset; Base Sequence; Child; Embryonic and Fetal Development; Fragile X Syndrome; Genetic Diseases, Inborn; Humans; Huntington Disease; Infant, Newborn; Intellectual Disability; Male; Methylation; Middle Aged; Molecular Sequence Data; Muscular Atrophy, Spinal; Myotonic Dystrophy; Repetitive Sequences, Nucleic Acid; Spermatozoa; Spinocerebellar Degenerations

1994
Proposed genetic basis of Huntington's disease.
    Trends in genetics : TIG, 1990, Volume: 6, Issue:8

    Topics: Adolescent; Adult; Age Factors; Alleles; Animals; Child; Child, Preschool; Chromosomes, Human, Pair 4; Drosophila melanogaster; Epistasis, Genetic; Female; Gene Expression Regulation; Genes; Genes, Dominant; Genes, Regulator; Heterozygote; Humans; Huntington Disease; Male; Methylation; Middle Aged; Models, Genetic; Transcription Factors; X Chromosome

1990

Other Studies

28 other study(ies) available for isomethyleugenol and Huntington Disease

ArticleYear
Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity.
    Human molecular genetics, 2022, 05-19, Volume: 31, Issue:10

    Topics: Animals; Arginine; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Nuclear Proteins; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Solubility

2022
Integrative Analysis Unveils the Correlation of Aminoacyl-tRNA Biosynthesis Metabolites with the Methylation of the
    Genes, 2023, 09-02, Volume: 14, Issue:9

    Topics: Amino Acyl-tRNA Synthetases; Brain; Humans; Huntington Disease; Metabolome; Methylation; RNA, Transfer

2023
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
    Cell reports, 2021, 04-13, Volume: 35, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Axonal Transport; Brain-Derived Neurotrophic Factor; Cell Death; Disease Models, Animal; Drosophila melanogaster; Epigenesis, Genetic; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neuromuscular Junction; Neurons; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Transport Vesicles

2021
ATP Binding Cassette Subfamily A Member 2 (ABCA2) Expression and Methylation are Associated with Alzheimer's Disease.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Dec-10, Volume: 23

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; ATP-Binding Cassette Transporters; Cognitive Dysfunction; CpG Islands; Databases, Genetic; Epigenesis, Genetic; Genetic Predisposition to Disease; Humans; Huntington Disease; Methylation; RNA, Messenger; Tissue Array Analysis; Up-Regulation

2017
Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease.
    Human molecular genetics, 2018, 02-15, Volume: 27, Issue:4

    Topics: Animals; Animals, Genetically Modified; Chromatin; Chromatin Immunoprecipitation; Drosophila melanogaster; Female; Heterochromatin; Histone Demethylases; Histones; Huntington Disease; Male; Methylation; Polycomb-Group Proteins

2018
Targeting H3K4 trimethylation in Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-06, Volume: 110, Issue:32

    Topics: Animals; Animals, Genetically Modified; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Drosophila melanogaster; Female; Gene Expression Profiling; Histone Demethylases; Histones; Humans; Huntingtin Protein; Huntington Disease; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nerve Tissue Proteins; Neurons; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2013
ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription.
    Nucleic acids research, 2014, Volume: 42, Issue:3

    Topics: Animals; Cell Line; Cell Nucleolus; DNA, Ribosomal; Heterochromatin; Histone-Lysine N-Methyltransferase; Humans; Huntington Disease; Methylation; Mice; Mutation; Pol1 Transcription Initiation Complex Proteins; Transcription, Genetic

2014
Epigenetic modifications as novel therapeutic targets for Huntington's disease.
    Epigenomics, 2014, Volume: 6, Issue:3

    Topics: Acetylation; Animals; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Nerve Tissue Proteins; Ubiquitination

2014
The Drosophila Huntington's disease gene ortholog dhtt influences chromatin regulation during development.
    Human molecular genetics, 2015, Jan-15, Volume: 24, Issue:2

    Topics: Animals; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation, Developmental; Heterochromatin; Humans; Huntingtin Protein; Huntington Disease; Male; Methylation; Microtubule-Associated Proteins; Ovary; Wings, Animal

2015
Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation.
    Biochemistry, 2010, Aug-24, Volume: 49, Issue:33

    Topics: Humans; Huntington Disease; Methylation; Peptides; Protein Structure, Secondary; Surface Plasmon Resonance

2010
ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease.
    Cell death and differentiation, 2012, Volume: 19, Issue:7

    Topics: Animals; Base Sequence; CDX2 Transcription Factor; Cell Line; DNA Helicases; Drosophila; Drosophila Proteins; Heterochromatin; Histones; Homeodomain Proteins; Humans; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; X-linked Nuclear Protein

2012
Transcription elongation and tissue-specific somatic CAG instability.
    PLoS genetics, 2012, Volume: 8, Issue:11

    Topics: Animals; Chromatin; Corpus Striatum; Disease Models, Animal; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Organ Specificity; Transcription, Genetic; Trinucleotide Repeat Expansion

2012
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
    The Journal of biological chemistry, 2005, Jan-07, Volume: 280, Issue:1

    Topics: Acetylation; Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Phenylbutyrates; Trinucleotide Repeat Expansion; Ubiquitin

2005
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-17, Volume: 24, Issue:46

    Topics: Animals; Antibiotics, Antineoplastic; Brain; Cells, Cultured; Gene Silencing; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Lysine; Male; Methylation; Mice; Mice, Transgenic; Mitochondria, Liver; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Plicamycin; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, Glutamate; Transcription, Genetic

2004
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-12, Volume: 103, Issue:50

    Topics: Aged; Animals; Cystamine; Female; Gene Expression; Histone-Lysine N-Methyltransferase; Histones; Humans; Huntington Disease; Male; Methylation; Mice; Middle Aged; Phenotype; Plicamycin; Promoter Regions, Genetic; Protein Methyltransferases; Sp3 Transcription Factor; Survival Rate; Up-Regulation

2006
Modulation of nucleosome dynamics in Huntington's disease.
    Human molecular genetics, 2007, May-15, Volume: 16, Issue:10

    Topics: Acetylation; Animals; Brain; Chromomycins; Disease Models, Animal; Female; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Plicamycin; Transcription, Genetic

2007
Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Apr-09, Volume: 28, Issue:15

    Topics: Animals; Brain; Cells, Cultured; Histones; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Repressor Proteins; Transcription, Genetic; Ubiquitination

2008
Age at onset in Huntington's disease and methylation at D4S95.
    Journal of medical genetics, 1993, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chromosomes, Human, Pair 4; DNA; Electrophoresis, Agar Gel; Female; Gene Expression Regulation; Humans; Huntington Disease; Male; Methylation; Middle Aged; Mutation; Paternal Age

1993
An estimate of the number of genes in the Huntington disease gene region and the identification of 13 transcripts in the 4p16.3 segment.
    Genomics, 1992, Volume: 13, Issue:4

    Topics: Blotting, Northern; Blotting, Southern; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 4; DNA; Electrophoresis, Gel, Pulsed-Field; Humans; Huntington Disease; Methylation; Restriction Mapping; Transcription, Genetic

1992
Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting.
    American journal of human genetics, 1992, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Age Factors; Birth Order; Child; DNA; Family Health; Female; Gene Expression Regulation; Humans; Huntington Disease; Least-Squares Analysis; Male; Maternal Age; Methylation; Middle Aged; Parents; Parity; Paternal Age; Regression Analysis; Sex Factors

1992
Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.
    Journal of medical genetics, 1991, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Age Factors; Alleles; Gene Expression; Genetic Variation; Humans; Huntington Disease; Methylation; Pedigree; Surveys and Questionnaires

1991
Identification of multiple CpG islands and associated conserved sequences in a candidate region for the Huntington disease gene.
    Genomics, 1991, Volume: 11, Issue:4

    Topics: Animals; Base Sequence; Biological Evolution; Chromosome Walking; Chromosomes, Human, Pair 4; Cloning, Molecular; Cosmids; Dinucleoside Phosphates; DNA; Electrophoresis, Gel, Pulsed-Field; Humans; Huntington Disease; Methylation; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Nucleic Acid

1991
Parental imprinting of genes.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Animals; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; DNA; Female; Genetic Diseases, Inborn; Genetics; Humans; Huntington Disease; Male; Methylation; Mice; Ovum; Rhabdomyosarcoma; Sex Chromosomes; Spermatozoa

1990
Possible organ and age-related epigenetic factors in Huntington's disease and colorectal carcinoma.
    Medical hypotheses, 1989, Volume: 29, Issue:1

    Topics: Aging; Animals; Chromosome Deletion; Colorectal Neoplasms; Gene Expression Regulation; Genes, Switch; Humans; Huntington Disease; Methylation; Mutation

1989
Methylation at the Huntington disease-linked D4S95 locus.
    American journal of human genetics, 1989, Volume: 45, Issue:2

    Topics: Alleles; Cell Line; DNA; Genetic Linkage; Humans; Huntington Disease; Methylation; Plasmids

1989
Methylation at the D4S95 locus and predictive testing.
    American journal of human genetics, 1989, Volume: 45, Issue:3

    Topics: Genetic Linkage; Genetic Markers; Humans; Huntington Disease; Methylation; Predictive Value of Tests; Repetitive Sequences, Nucleic Acid

1989
Anticipation in Huntington's disease is inherited through the male line but may originate in the female.
    Journal of medical genetics, 1988, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Age Factors; Alleles; DNA; Epidemiologic Methods; Female; Humans; Huntington Disease; Male; Methylation; Sex Factors; United States

1988
Genomic imprinting: a possible mechanism for the parental origin effect in Huntington's chorea.
    Journal of medical genetics, 1988, Volume: 25, Issue:12

    Topics: Age Factors; Alleles; Animals; Gene Expression Regulation; Humans; Huntington Disease; Methylation; Mice; Sex Characteristics

1988