Compounds > isomethyleugenol
Page last updated: 2024-08-18

isomethyleugenol and Glioma

isomethyleugenol has been researched along with Glioma in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-19907 (5.43)18.7374
1990's14 (10.85)18.2507
2000's10 (7.75)29.6817
2010's48 (37.21)24.3611
2020's50 (38.76)2.80

Authors

AuthorsStudies
Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Jefferies, S; Kelly, C; Kurian, KM; McAleenan, A; Schmidt, L; Spiga, F; Wragg, C1
Chen, G; Huang, H; Luo, S; Tang, G; Wang, FF1
Chang, J; Wang, L; Xu, W; Yuan, J; Zhou, X1
Hölzl, D; Kral, M; Kraus, TFJ; Ladisich, B; Machegger, L; Pöppe, J; Schlicker, HU; Schwartz, C; Sotlar, K; Spendel, M; Zellinger, B1
Cheng, X; Gao, Y; Han, Z; Jin, H; Li, P; Liang, W; Lin, S; Liu, Z; Luan, Z; Qian, R1
McDonald, KL; Noor, H; Whittaker, S1
Cao, H; Chao, M; Chen, F; Wang, L; Xie, X1
Chu, Q; Lou, Y; Lv, P; Mao, M; Wang, LJ1
Dong, W; Liu, L; Liu, X; Ruan, X; Shao, L; Wang, D; Wang, P; Xue, Y; Yang, C; Zhang, M1
Jiang, J; Wang, S; Xu, Z1
Feng, N; Wei, Y; Wu, B; Xiang, Z; Zhang, W; Zhang, X; Zhao, B1
Ebrahimi, A; Herrlinger, U; Kaluza, L; Pietsch, T; Waha, A1
Bao, Y; Li, H; Ma, C; Xiao, B; Xu, J1
Booth, TC; Salihoğlu, AK1
Hu, X; Liu, H; Liu, L; Luo, T; Wang, J; Zhang, C; Zhen, Z; Zheng, Y1
Ajuyah, P; Barahona, P; Chambers, H; Cowley, MJ; D'Arcy, C; Ekert, PG; Gifford, AJ; Haber, M; Hansford, JR; Khuong-Quang, DA; Lau, LMS; Manoharan, N; Mayoh, C; Nicholls, W; Senapati, A; Tyrrell, V; Valdes-Mora, F; Williams, MM; Wong, M; Wood, PJ; Ziegler, DS1
Guowei, L; Qianqian, X; Xiufang, L; Yanping, J1
Baihetiyaer, Y; Feng, Z; Jiang, L; Kasimu, M; Liu, Y; Maimaiti, A; Pei, Y; Turhon, M; Wang, X; Wang, Y; Wang, Z; Xie, Z1
Bruce, JN; Canoll, PD; Cheng, SK; Grinband, J; Iwamoto, FM; Kachnic, LA; Kinslow, CJ; Kumar, P; McKhann, GM; Mercurio, A; Rae, AI; Siegelin, MD; Sisti, MB; Taparra, K; Upadhyayula, PS; Wang, TJC; Yu, JB1
Ferrer, VP; Machado, GC1
Bruce, JN; Canoll, PD; Cheng, SK; Gill, BJA; Grinband, J; Horowitz, DP; Iwamoto, FM; Kachnic, LA; Kinslow, CJ; Kumar, P; McKhann, GM; Neugut, AI; Rae, AI; Siegelin, MD; Sisti, MB; Taparra, K; Wang, TJC; Yu, JB1
Li, N; Li, X; Li, Y; Li, Z; Shen, L1
Chen, J; Chen, X; Chen, Y; Cheng, Z; Duan, H; Huang, Y; Li, K; Li, Q; Li, Y; Lin, X; Liu, J; Lu, Y; Pan, G; Qin, Z; Shen, X; Shu, M; Wang, F; Wang, G; Wang, X; Xing, F; Yang, S; Zeng, Y; Zhang, H; Zhang, Y1
Li, J; Liang, C; Liu, Q; Liu, Y; Xiao, Z; Yan, X; Zhang, Y1
Chen, J; Huang, X; Jiang, J; Li, X; Li, Z; Liu, R; Long, S; Wang, L; Wei, W; Xu, H; Xu, Z; Yan, Y; Zhou, Q1
Chen, R; Chen, X; Gimple, RC; Jiang, T; Lin, P; Liu, L; Liu, Q; Liu, X; Liu, Z; Luo, J; Prager, BC; Rich, JN; Wang, D; Wu, E; Wu, Q; Wu, W; Xie, Q; Yu, J; Zhang, W; Zhang, Y; Zhao, W1
Andrade, J; Garcia, BA; Granat, J; Jin, Y; Lee, CH; LeRoy, G; Lund, P; Reinberg, D; Saldaña-Meyer, R; Stafford, JM; Ueberheide, B; Yu, JR1
Chen, Y; Ge, J; Wang, X; Wu, B; Zhong, S1
Li, F; Zhang, C; Zhang, G1
Chen, W; Feng, F; Feng, S; Jiang, C; Kong, Z; Liu, S; Lyu, Y; Ma, W; Wang, R; Wang, Y; You, H; Zhang, Y; Zhao, D; Zhu, R1
Chen, Y; Deng, Y; Lodhi, AF; Ma, H; Sun, C; Sun, F; Wang, H; Yan, L; Zhang, P1
Cao, X; Du, F; Gao, Y; Guo, Y; Li, PA; Lv, Y; Wang, F; Wang, S; Wu, Y; Yu, J1
Hatanaka, KC; Hida, K; Ishi, Y; Ishida, Y; Oda, Y; Seki, T; Takamiya, S; Tanaka, S; Yamaguchi, S; Yamazaki, K1
Hao, L; Li, M; Liu, L; Ma, L; Song, S; Wang, G; Wang, L; Yu, C; Zhang, Z1
Alkam, D; Day, JD; De Loose, A; Ho, SM; Jenjaroenpun, P; Leung, YK; Nookaew, I; Rodriguez, A; Ussery, DW; Wongsurawat, T1
Cahill, DP; Miller, JJ1
Allis, CD; Deshmukh, S; Garcia, BA; Jabado, N; Jain, SU; Juretic, N; Khazaei, S; Lewis, PW; Lu, C; Lundgren, SM; Marchione, DM; Wang, X; Weinberg, DN1
Cheng, H; Dai, X; Hu, Y; Wang, H; Wang, J; Wu, B; Ye, L1
Bareke, E; Chen, H; Coradin, M; Garcia, BA; Harutyunyan, AS; Horth, C; Jabado, N; Krug, B; Lu, T; Majewski, J; Marchione, DM; Nikbakht, H; Russo, C1
Cai, H; Chen, F; Chen, Z; Hu, Y; Li, C; Ni, X; Wang, J; Xi, S; Yu, Y1
Agnihotri, S; Bridge, T; Hawkins, C; Huang, A; Kim, B; Li, C; Milos, S; Pajovic, S; Patel, P; Phillips, L; Rakopoulos, P; Ryall, S; Sheth, J; Siddaway, R; Srikanthan, D; Yu, M1
Bartom, E; Huang, TY; Morgan, M; Piunti, A; Qi, J; Saratsis, AM; Shilatifard, A1
Chen, N; Gong, Q; Su, X; Sun, H; Tan, Q; Wan, X; Wang, W; Yang, X; Yue, Q; Zhang, S1
Li, X; Meng, Y1
Guo, L; He, W; Hua, J; Li, X; Liao, S; Liu, X; Wang, W; Wu, Y; Xiao, X; Xu, Y; Zhou, J1
Huang, J; Liu, J; Qiu, O; Qu, S; Wang, H1
Navarria, P; Pessina, F; Politi, LS; Simonelli, M1
Chen, J; Du, J; Huang, X; Huang, Z; Lan, W; Lin, Q; Lin, W; Ma, W; Shen, Y; Yao, X; Zhang, N; Zheng, B1
Horbinski, C; McCortney, K; Stupp, R1
Jiang, X; Qiu, Y; Wang, M; Wang, X; Wu, Z; Yu, H; Zheng, J; Zhou, Z1
Chen, SH; Cui, WY; Lv, QL; Shen, XL; Tan, ZL; Wang, LC; Zhang, Z1
Li, L; Pan, T; Sun, C; Wu, F; Wu, S; Xia, L; Zhang, P; Zhou, F1
Anderson, J; Cantilena, S; de Boer, J; Hargrave, D; Meier, S; Michod, D; Niklison Chirou, MV; Salomoni, P1
Guan, S; He, Y; Su, Y; Zhou, L1
Carman, C; Gursoy-Yuzugullu, O; Myronakis, M; Price, BD; Serafim, RB; Valente, V1
Akagi, Y; Hata, N; Hatae, R; Hideki, M; Hiwatashi, A; Iihara, K; Iwaki, T; Kuga, D; Mizoguchi, M; Sangatsuda, Y; Suzuki, SO; Togao, O; Yamashita, K; Yoshimoto, K1
Aguiar, RCT; Dahia, PLM; Elkashef, SM; Jiang, D; Lin, AP; Myers, J; Sill, H1
Ding, Y; Dong, MQ; Geng, Q; Li, J; Li, X; Nai, S; Su, XD; Xu, X; Yu, K; Zhu, B; Zhu, WG1
Dai, B; Guan, F; Hu, Z; Huang, H; Mao, B; Su, H; Xiao, Z; Zhu, G1
Cai, J; Dinislam, M; Duan, C; Gao, F; Gao, W; Han, B; Jiang, C; Kang, C; Lin, L; Meng, X; Wang, R; Wu, P1
Deng, J; Jiao, X; Li, J; Qiu, D; Sun, Z; Wan, X; Xia, Z; Yang, R1
Bender, B; Bier, G; Brendle, C; Castaneda Vega, S; Ernemann, U; Hempel, JM; Klose, U; Schittenhelm, J; Skardelly, M; Tabatabai, G1
Marosi, C1
Arnold, EP; Haile, S; Hulleman, E; Kadapakkam, M; Labanieh, L; Mackall, CL; Majzner, RG; Monje, M; Mount, CW; Rietberg, SP; Sundaresh, S; Vogel, H; Woo, PJ1
Chang, JF; Chen, L; He, ZM; Jiang, CZ; Jing, YY; Kang, X; Liu, KN; Mao, ZY; Shen, Y; Sun, FL; Sun, J; Tang, HY; Wang, C; Wang, DL; Wei, HM; Wu, JY; Xu, RG; Yang, XM; Zeng, SY; Zhang, Y; Zhu, RB1
Cheng, L; Daniels, DJ; Fang, D; Gan, H; Lee, JH; Sarkaria, JN; Zhang, Z; Zhou, H1
Choi, SH; Chun, SJ; Kim, IH; Kim, JW; Kim, TM; Lee, ST; Park, CK; Park, SH1
Fang, J; Gu, L; Huang, Y; Li, GM; Li, H; Mao, G; Rennert, G; Yang, S1
Chen, H; Dong, Z; Liu, M; Liu, Y; Ma, C; Wang, Y; Wu, R; Yan, Y; Yang, L1
Chen, W; Chen, Y; Deng, X; Lian, M; Long, H; Qian, D; Shi, P; Wang, H; Wang, K; Xiao, D1
Delaney, K; Pankowski, A; Steiner, FA; Strobino, M; Wenda, JM1
Albrecht, S; Bognar, L; Busche, S; Faury, D; Fleming, A; Fontebasso, AM; Garami, M; Gerges, N; Hadjadj, D; Hauser, P; Jabado, N; Jones, DT; Khuong-Quang, DA; Klekner, A; Kool, M; Korshunov, A; Lepage, P; Liberski, PP; Liu, XY; Majewski, J; Montpetit, A; Pfister, SM; Schwartzentruber, J; Staffa, A; Sturm, D; Witt, H; Zadeh, G; Zakrzewska, M; Zakrzewski, K1
Biller, SA; Brennan, CW; Campos, C; Chan, TA; Chen, Y; Clark, O; Graeber, TG; Grommes, C; Kernytsky, A; Komisopoulou, E; Kunii, K; Liu, W; Mellinghoff, IK; Miller, A; Oldrini, B; Palaskas, N; Pedraza, A; Popovici-Muller, J; Rohle, D; Rosenblum, MK; Schalm, S; Silverman, L; Su, SM; Tsoi, J; Turcan, S; Wang, F; Yang, H; Yen, KE1
Chan, KM; Fang, D; Gan, H; Gupta, N; Hashizume, R; James, CD; Jenkins, R; Mueller, S; Sarkaria, J; Schroeder, M; Yu, C; Zhang, Z1
Collins, VP; Harris, FP; Jefferies, SJ; Price, SJ; Watts, C1
Byun, HS; Choi, SW; Hong, JH; Huang, SM; Hur, GM; Jeon, J; Kim, JM; Kim, SH; Lee, JH; Lee, Y; Li, Y; Liu, ZG; Lu, T; Park, J; Park, KA; Ro, H; Shen, HM; Sohn, KC; Stark, GR; Zhang, T1
Arita, H; Fukushima, S; Ichimura, K; Matsushita, Y; Miyakita, Y; Narita, Y; Ohno, M; Shibui, S; Takami, H; Yoshida, A1
Feng, D; Hu, Q; Li, H; Ma, H; Su, Y; Tao, H; Wang, X; Zhang, C1
Eissenberg, JC; Florens, L; Gao, X; Herz, HM; Jackson, J; Morgan, M; Rickels, R; Shilatifard, A; Swanson, SK; Washburn, MP1
Chapet, S; Lévy, S; Mazeron, JJ1
Andor, N; Chen, X; Fang, D; Gan, H; Gupta, N; Hashizume, R; Huang, X; Ihara, Y; James, CD; Lerner, R; Mueller, S; Ngo, V; Paris, PL; Petritsch, C; Solomon, D; Tom, MW; Waldman, TA; Zhang, Z1
He, W; Liu, R; Yang, SH; Yuan, F1
Filatov, MV; Kovalev, RA; Semenova, EV; Shtam, TA; Volnitskiĭ, AV1
Cui, H; Matthiesen, R; Mu, Y; Su, X; Sun, W; Xi, YG; Yu, L1
Alyami, W; Bouhlel, A; Li, A; McConathy, J; Rich, K; Yuan, L1
Bjerkvig, R; Johannessen, TA; Mukherjee, J; Ohba, S; Pieper, RO; Ronen, SM; Viswanath, P1
Balvers, RK; Dirven, CM; Lamfers, ML; Leenstra, S1
Allis, CD; Lu, C; Weinberg, DN1
Abshiru, NA; Bartom, ET; Hashizume, R; Horbinski, CM; James, CD; Kelleher, NL; Lulla, RR; Ma, Q; Marshall, SA; Misharin, AV; Morgan, MA; Piunti, A; Rendleman, EJ; Saratsis, AM; Shilatifard, A; Takahashi, YH; Woodfin, AR1
Gurley, S; Krishnamurthy, M; Moore, BM1
Chen, T; Gao, J; Gong, Y; Guo, X; Hu, G; Liu, J; Liu, W; Peng, X; Qiang, B; Yin, B; Yuan, J; Zhao, J1
Cerdán, S; López-Larrubia, P; Rodrigues, TB1
Chen, Y; Hu, C; Shen, L; Wang, H; Wang, S; Wang, Z; Yue, W; Zhang, X; Zhou, J1
Catapano, G; D'Urso, OF; D'Urso, PI; Gianfreda, CD; Marsigliante, S; Montinaro, A; Muscella, A; Storelli, C1
Hartmann, C; Korshunov, A; von Deimling, A1
Fukushima, T; Katayama, Y; Nagase, H; Ohta, T; Shinojima, Y; Terui, T; Watanabe, T; Yachi, K; Yoshino, A2
Abdel-Wahab, O; Berger, SL; Chan, TA; Edwards, CR; Figueroa, ME; Kapoor, GS; Khanin, R; Levine, RL; Lu, C; Mellinghoff, IK; Melnick, A; O'Rourke, DM; Rohle, D; Thompson, CB; Turcan, S; Ward, PS; Wellen, KE1
Peng, X; Qiang, B; Tan, X; Wang, S; Yang, B; Yin, B; Yuan, J1
Geng, J; Luo, H; Pu, Y; Wu, X; Xu, W; Yang, Z; Zhou, Z1
Adamopoulos, C; Papavassiliou, AG; Piperi, C; Spyropoulou, A1
Laird, PW; Marczinek, K; Nürnberg, P; Rohde, K; Szymas, J; Thiel, G; Uhlmann, K; Vogel, S; Zeller, C1
Godfraind, C; Rousseau, E; Ruchoux, MM; Scaravilli, F; Vikkula, M1
Itaba, N; Kamitani, H; Maegawa, S; Nanba, E; Oshimura, M; Otsuka, S; Tahimic, CG; Watanabe, T1
Gao, Y; Guan, M; Liu, W; Lu, Y; Su, B; Xu, M1
Desrosiers, RR; Lanthier, J; Lapointe, M; Moumdjian, R; Régina, A1
Makrigiorgos, GM; Price, BD; Roy, K; Wang, L1
du Plessis, DG; Dunn, JR; Gee, AL; Moss, DJ; Reed, JE; Reeves, P; Sellar, GC; Shaw, EJ; Walker, C; Warnke, PC1
Cheah, MS; Hoffman, RM; Wallace, CD1
Koschel, K; Münzel, P1
Costello, JF; Futscher, BW; Kroes, RA; Pieper, RO1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D1
Berger, MS; Blank, A; Bobola, MS; Silber, JR1
Braun, PE; Cox, ME; Gao, EN1
Costello, JF; Futscher, BW; Graunke, DM; Pieper, RO; Tano, K1
Chiba, M; Gasa, S; Hashi, K; Ibayashi, Y; Suetake, K; Taki, T; Yamaki, T1
Berger, MS; Cavenee, WK; Costello, JF; Huang, HS1
Baylin, SB; Herman, JG; Jen, J; Merlo, A1
Aoki, Y; Kayama, T; Komura, J; Nakura, H; Nata, M; Ono, T; Sagisaka, K; Sakurai, H; Sasano, H; Tawa, R; Uyeno, S; Yoshimoto, T1
Costello, JF; Futscher, BW; Patel, S; Pieper, RO; Ting, SA1
Endo, S; Feng, X; Ichikawa, T; Koga, H; Kumanishi, T; Onda, K; Washiyama, K; Zhang, S1
Bruner, JM; Fueyo, J; Gomez-Manzano, C; Kyritsis, AP; Levin, VA; Saito, Y; Yung, WK; Zhang, B; Zhang, W1
de Graaf, RA; Garwood, M; Gruetter, R; Luo, Y; Rydzewski, J; Schleich, T1
Akira, S; Hirano, T; Isshiki, H; Kishimoto, T; Nakajima, T; Shimamoto, T; Tanabe, O1
Brophy, PJ; Gillespie, CS; McKenzie, RC1
Aida, T; Bodell, WJ1
Perria, L; Viale, GL1
Viale, GL1
Grosso, G; Kroh, H; Viale, E; Viale, GL1

Reviews

14 review(s) available for isomethyleugenol and Glioma

ArticleYear
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
    Neuro-oncology, 2021, 09-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Glioma; Humans; Methylation; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2021
Diagnostic performance of radiomics using machine learning algorithms to predict MGMT promoter methylation status in glioma patients: a meta-analysis.
    Diagnostic and interventional radiology (Ankara, Turkey), 2021, Volume: 27, Issue:6

    Topics: Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Machine Learning; Methylation; Tumor Suppressor Proteins

2021
A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature.
    Brain tumor pathology, 2022, Volume: 39, Issue:2

    Topics: Astrocytoma; Biology; Brain Neoplasms; Chromosomes, Human, Pair 1; DNA; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Oligodendroglioma

2022
The Potential Value of m6A RNA Methylation in the Development of Cancers Focus on Malignant Glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Glioblastoma; Glioma; Humans; Methylation; RNA; Tumor Microenvironment

2022
The Critical Role of RNA m
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:5

    Topics: Apoptosis; Glioma; Humans; Methylation; MicroRNAs; RNA, Messenger; Tumor Microenvironment

2023
Insights into the regulatory role of RNA methylation modifications in glioma.
    Journal of translational medicine, 2023, 11-14, Volume: 21, Issue:1

    Topics: 5-Methylcytosine; Glioma; Humans; Methylation; RNA; Transcriptome

2023
The role m
    Molecular brain, 2021, 07-19, Volume: 14, Issue:1

    Topics: Adenosine; Animals; Central Nervous System; Glioma; Humans; Methylation; Models, Biological; RNA

2021
[Management of gliomas].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Chromosome Deletion; Chromosomes, Human, Pair 1; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Dose Fractionation, Radiation; Drug Resistance, Neoplasm; Glioma; Humans; Lomustine; Methylation; Multicenter Studies as Topic; Neoplasm Proteins; Neurosurgical Procedures; O(6)-Methylguanine-DNA Methyltransferase; Procarbazine; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Temozolomide; Treatment Outcome; Vincristine

2014
Malignant Glioma In Vitro Models: On the Utilization of Stem-like Cells.
    Current cancer drug targets, 2017, Volume: 17, Issue:3

    Topics: Biopsy; Cell Culture Techniques; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Neoplastic Stem Cells; Tumor Cells, Cultured

2017
Oncogenic Mechanisms of Histone H3 Mutations.
    Cold Spring Harbor perspectives in medicine, 2017, Jan-03, Volume: 7, Issue:1

    Topics: Carcinogenesis; Chromatin; Glioma; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mutation, Missense; Protein Processing, Post-Translational

2017
The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations.
    Brain pathology (Zurich, Switzerland), 2011, Volume: 21, Issue:1

    Topics: Biomarkers, Tumor; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Proto-Oncogene Proteins B-raf; Tumor Suppressor Proteins

2011
Non-promoter hypermethylation of zygote arrest 1 (ZAR1) in human brain tumors.
    Brain tumor pathology, 2011, Volume: 28, Issue:3

    Topics: Adenoma; Biomarkers, Tumor; Brain Neoplasms; Egg Proteins; Glioma; Humans; Methylation; Oligonucleotide Array Sequence Analysis; Oocytes; Pituitary Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Zygote

2011
Deregulated chromatin remodeling in the pathobiology of brain tumors.
    Neuromolecular medicine, 2013, Volume: 15, Issue:1

    Topics: Acetylation; Adenosine Triphosphate; Antineoplastic Agents; Brain Neoplasms; Chromatin Assembly and Disassembly; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Macromolecular Substances; Methylation; Molecular Targeted Therapy; Neoplasm Proteins; Nucleosomes; Protein Processing, Post-Translational

2013
The RNA-overmethylation in brain tumours. Data and hypothesis.
    Acta neurochirurgica, 1969, Volume: 21, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Differentiation; Cytogenetics; Glioma; Humans; Methylation; Mutation; Ribosomes; RNA, Neoplasm; RNA, Transfer

1969

Other Studies

115 other study(ies) available for isomethyleugenol and Glioma

ArticleYear
The CBL-LSD1-CXCL8 axis regulates methionine metabolism in glioma.
    Cytokine, 2022, Volume: 151

    Topics: Cell Line, Tumor; Glioma; Histone Demethylases; Humans; Methionine; Methylation; Tumor Microenvironment

2022
Prognostic Significance of mRNA Expression RBBP8 or Its Methylation in Gliomas.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:1

    Topics: Brain Neoplasms; Endodeoxyribonucleases; Glioma; Humans; Methylation; Prognosis; RNA, Messenger; Tumor Microenvironment

2023
DLL3 expression and methylation are associated with lower-grade glioma immune microenvironment and prognosis.
    Genomics, 2022, Volume: 114, Issue:2

    Topics: Biomarkers, Tumor; Brain Neoplasms; Epigenesis, Genetic; Glioma; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Methylation; Prognosis; Tumor Microenvironment

2022
RNA N1-methyladenosine regulator-mediated methylation modification patterns and heterogeneous signatures in glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Brain Neoplasms; Gene Expression Regulation, Neoplastic; Glioma; Humans; Methylation; RNA; Tumor Microenvironment

2022
CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.
    Communications biology, 2022, 09-05, Volume: 5, Issue:1

    Topics: Animals; Astrocytes; Brain Neoplasms; Endothelial Cells; Epigenesis, Genetic; Glioma; Humans; Methylation; Methyltransferases; Mice; MicroRNAs; Microvessels; Permeability; RNA Splicing Factors; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Zonula Occludens-1 Protein

2022
Use of Novel m6A Regulator-mediated Methylation Modification Patterns in Distinct Tumor Microenvironment Profiles to Identify and Predict Glioma Prognosis and Progression, T-cell Dysfunction, and Clinical Response to ICI Immunotherapy.
    Current pharmaceutical design, 2023, Volume: 29, Issue:1

    Topics: Glioma; Humans; Immunotherapy; Methylation; Prognosis; T-Lymphocytes; Tumor Microenvironment

2023
Methylation class oligosarcoma may encompass IDH-wildtype gliomas.
    Acta neuropathologica, 2023, Volume: 145, Issue:3

    Topics: Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation

2023
Identification and validation of RNA methylation-related alternative splicing gene signature for low-grade glioma to predict survival and immune landscapes.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:1

    Topics: Alternative Splicing; Glioma; Humans; Methylation; Nomograms; RNA; Tumor Microenvironment

2023
Editorial for "Apparent Diffusion Coefficient as Imaging Biomarker for Identifying IDH Mutation, 1p19q Codeletion, and MGMT Promoter Methylation Status in Patients With Glioma".
    Journal of magnetic resonance imaging : JMRI, 2023, Volume: 58, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Tumor Suppressor Proteins

2023
Correlation between ITGB2 expression and clinical characterization of glioma and the prognostic significance of its methylation in low-grade glioma(LGG).
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: CD18 Antigens; Glioma; Humans; Integrins; Methylation; Prognosis; Reproducibility of Results

2022
Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.
    Scientific reports, 2023, 03-07, Volume: 13, Issue:1

    Topics: Activin Receptors, Type I; Child; ErbB Receptors; Genes, Homeobox; Glioma; Histones; Humans; Methylation; Mutation

2023
The FDX1 methylation regulatory mechanism in the malignant phenotype of glioma.
    Genomics, 2023, Volume: 115, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Ferredoxins; Glioma; Methylation; MicroRNAs; Phenotype

2023
N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma.
    European journal of medical research, 2023, Mar-30, Volume: 28, Issue:1

    Topics: Algorithms; Carcinogenesis; Gene Expression; Glioma; Humans; Methylation; Tumor Microenvironment

2023
Association of MGMT Promoter Methylation With Survival in Low-grade and Anaplastic Gliomas After Alkylating Chemotherapy.
    JAMA oncology, 2023, 07-01, Volume: 9, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Male; Methylation; Prognosis; Prospective Studies; Tumor Suppressor Proteins

2023
MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients.
    Journal of the neurological sciences, 2023, 09-15, Volume: 452

    Topics: Adult; Brain Neoplasms; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mucins; Mutation; Prognosis; Retrospective Studies

2023
MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 11-01, Volume: 29, Issue:21

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Prognosis; Tumor Suppressor Proteins

2023
Integrative analyses reveal biological function and prognostic role of m7G methylation regulators in high-grade glioma.
    Aging, 2023, 09-06, Volume: 15, Issue:17

    Topics: Glioma; Humans; Inflammation; Methylation; Prognosis; Tumor Microenvironment

2023
IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma.
    Nature communications, 2023, 10-25, Volume: 14, Issue:1

    Topics: Animals; Brain Neoplasms; Female; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mice; Mutation; Oncolytic Virotherapy; Oncolytic Viruses

2023
Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma.
    Aging, 2023, 11-06, Volume: 15, Issue:21

    Topics: Brain Neoplasms; Glioma; Humans; Methylation; Prognosis; rap GTP-Binding Proteins; RNA; Tumor Microenvironment

2023
LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation.
    Nature communications, 2023, 11-18, Volume: 14, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Methylation; Neoplastic Stem Cells; Ribonucleoproteins, Small Nucleolar; RNA, Long Noncoding

2023
Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma.
    Genes & development, 2019, 10-01, Volume: 33, Issue:19-20

    Topics: Child; Enzyme Activation; Gene Silencing; Glioma; Histones; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Subunits

2019
Further Investigation About Copy Number Variations and Methylation of HADC3 in Glioma.
    World neurosurgery, 2019, Volume: 126

    Topics: DNA Copy Number Variations; Glioma; Humans; Methylation; Prognosis; Transcriptome

2019
m6A RNA Methylation Controls Proliferation of Human Glioma Cells by Influencing Cell Apoptosis.
    Cytogenetic and genome research, 2019, Volume: 159, Issue:3

    Topics: Adenosine; Apoptosis; Brain Neoplasms; Cell Line; Cell Movement; Cell Proliferation; Glioma; Humans; Methylation; Methyltransferases

2019
Fusion Radiomics Features from Conventional MRI Predict MGMT Promoter Methylation Status in Lower Grade Gliomas.
    European journal of radiology, 2019, Volume: 121

    Topics: Adult; Area Under Curve; Brain; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Reproducibility of Results; Retrospective Studies; ROC Curve; Tumor Suppressor Proteins

2019
DR5 related autophagy can promote apoptosis in gliomas after irradiation.
    Biochemical and biophysical research communications, 2020, 02-19, Volume: 522, Issue:4

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Caspase 8; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Methylation; Receptors, TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic

2020
Polycomb-like 2 regulates PRC2 components to affect proliferation in glioma cells.
    Journal of neuro-oncology, 2020, Volume: 148, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Histones; Humans; Methylation; Polycomb Repressive Complex 2

2020
Prognostic role of H3K27M mutation, histone H3K27 methylation status, and EZH2 expression in diffuse spinal cord gliomas.
    Brain tumor pathology, 2020, Volume: 37, Issue:3

    Topics: Enhancer of Zeste Homolog 2 Protein; Gene Expression; Glioma; Histones; Humans; Methylation; Mutation, Missense; Prognosis; Retrospective Studies; Spinal Cord Neoplasms

2020
Computational identification and characterization of glioma candidate biomarkers through multi-omics integrative profiling.
    Biology direct, 2020, 06-15, Volume: 15, Issue:1

    Topics: Biomarkers, Tumor; Brain Neoplasms; Computational Biology; Gene Expression; Glioma; Humans; Methylation; Protein Kinase C

2020
A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma.
    Acta neuropathologica communications, 2020, 06-20, Volume: 8, Issue:1

    Topics: Adult; Aged; Alcohol Oxidoreductases; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Line, Tumor; CRISPR-Associated Protein 9; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Methylation; Middle Aged; Pilot Projects; Sequence Analysis, RNA; Tumor Suppressor Proteins; Young Adult

2020
MGMT promoter methylation and hypermutant recurrence in IDH mutant lower-grade glioma.
    Neuro-oncology, 2020, 11-26, Volume: 22, Issue:11

    Topics: DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Methylation; Promoter Regions, Genetic; Tumor Suppressor Proteins

2020
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 11-03, Volume: 117, Issue:44

    Topics: Chromatin; Gene Expression; Gene Expression Regulation; Glioma; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mesenchymal Stem Cells; Methylation; Mutation; Neoplastic Processes; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Protein Processing, Post-Translational

2020
Methylation associated miR-1246 contributes to poor prognosis in gliomas treated with temozolomide.
    Clinical neurology and neurosurgery, 2021, Volume: 200

    Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; MicroRNAs; Prognosis; Temozolomide

2021
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation.
    Cell reports, 2020, 11-17, Volume: 33, Issue:7

    Topics: Cell Line, Tumor; Chromatin; DNA Methylation; Epigenomics; Gene Expression; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methionine; Methylation; Mutation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational

2020
LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis.
    Cell death & disease, 2020, 12-02, Volume: 11, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromosomal Proteins, Non-Histone; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Methylation; MicroRNAs; Phenotype; Promoter Regions, Genetic; Proteolysis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; RNA, Long Noncoding; Signal Transduction; Survival Analysis; TOR Serine-Threonine Kinases; Ubiquitination

2020
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
    Nature communications, 2020, 12-04, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methylation; Mice, Knockout; Proto-Oncogene Proteins c-myc; ras Proteins; Tumor Suppressor Protein p53

2020
Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.
    Acta neuropathologica communications, 2020, 12-07, Volume: 8, Issue:1

    Topics: Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Chromatin Immunoprecipitation; Chromatin Immunoprecipitation Sequencing; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; High-Throughput Nucleotide Sequencing; Histone Code; Histones; Humans; Methylation; Mutation, Missense

2020
Automated machine learning to predict the co-occurrence of isocitrate dehydrogenase mutations and O
    Journal of magnetic resonance imaging : JMRI, 2021, Volume: 54, Issue:1

    Topics: Brain Neoplasms; DNA; Glioma; Humans; Isocitrate Dehydrogenase; Machine Learning; Magnetic Resonance Imaging; Methylation; Methyltransferases; Mutation; Retrospective Studies

2021
Expression and prognostic characteristics of m
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:3

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Methylation; Neoplasm Grading; Prognosis; RNA; ROC Curve; Transcriptome

2021
Noninvasive Assessment of O(6)-Methylguanine-DNA Methyltransferase Promoter Methylation Status in World Health Organization Grade II-IV Glioma Using Histogram Analysis of Inflow-Based Vascular-Space-Occupancy Combined with Structural Magnetic Resonance Im
    Journal of magnetic resonance imaging : JMRI, 2021, Volume: 54, Issue:1

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Magnetic Resonance Imaging; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Retrospective Studies; World Health Organization

2021
Upregulation of hsa-miR-196a-5p is associated with MIR196A2 methylation and affects the malignant biological behaviors of glioma.
    Genomics, 2021, Volume: 113, Issue:3

    Topics: Carcinogenesis; Gene Expression Regulation, Neoplastic; Glioma; Humans; Methylation; MicroRNAs; Up-Regulation

2021
Editorial for "Noninvasive Assessment of MGMT Promoter Methylation Status in World Health Organization Grade II-IV Glioma Using Histogram Analysis of Inflow-Based Vascular-Space Occupancy Combined with Structural MR Imaging".
    Journal of magnetic resonance imaging : JMRI, 2021, Volume: 54, Issue:1

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Magnetic Resonance Imaging; Methylation; Promoter Regions, Genetic; Tumor Suppressor Proteins; World Health Organization

2021
Identification and characterization of a novel mutant isocitrate dehydrogenase 1 inhibitor for glioma treatment.
    Biochemical and biophysical research communications, 2021, 04-30, Volume: 551

    Topics: Benzeneacetamides; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Stability; Glioma; Histones; Humans; Imidazoles; Isocitrate Dehydrogenase; Methylation; Models, Molecular; Molecular Targeted Therapy; Mutant Proteins; Mutation; Protein Binding

2021
MGMT promoter methylation is associated with patient age and 1p/19q status in IDH-mutant gliomas.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Infant; Isocitrate Dehydrogenase; Methylation; Mutation; Promoter Regions, Genetic; Tumor Suppressor Proteins

2021
Identification of Critical m
    BioMed research international, 2021, Volume: 2021

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cluster Analysis; Computational Biology; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Methylation; Middle Aged; Prognosis; Risk Factors; RNA; Transcriptome; Tumor Microenvironment

2021
Expression, methylation and prognostic feature of EMILIN2 in Low-Grade-Glioma.
    Brain research bulletin, 2021, Volume: 175

    Topics: Adult; Aging; Biomarkers, Tumor; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Survival Analysis; Transcriptome

2021
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation.
    Cell death & disease, 2021, 08-11, Volume: 12, Issue:8

    Topics: Alcoholism; Auranofin; Cell Line, Tumor; Cell Proliferation; Child; Disulfiram; Down-Regulation; Drug Repositioning; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioma; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Myeloid-Lymphoid Leukemia Protein; Neoplasm Grading; Protein Processing, Post-Translational; Proteolysis; Transcription, Genetic

2021
A Risk Signature Consisting of Eight m
    Cellular and molecular neurobiology, 2022, Volume: 42, Issue:8

    Topics: Adenosine; Gene Expression Regulation, Neoplastic; Glioma; Humans; Methylation; Protein Processing, Post-Translational; RNA-Binding Proteins

2022
Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity.
    Oncotarget, 2017, Apr-11, Volume: 8, Issue:15

    Topics: DNA Damage; Glioma; Histones; Humans; Methylation; Radiation-Sensitizing Agents; Signal Transduction

2017
Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.
    Brain tumor pathology, 2017, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Calcinosis; Child; Child, Preschool; Female; Glioma; Histones; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Mutation; Neoplasm Staging; Prevalence; Retrospective Studies; Young Adult

2017
IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation.
    Cancer cell, 2017, 05-08, Volume: 31, Issue:5

    Topics: Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; RNA

2017
Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.
    Cell cycle (Georgetown, Tex.), 2017, Oct-18, Volume: 16, Issue:20

    Topics: Amino Acid Sequence; Asian People; Cell Cycle Proteins; DNA Replication; Ethnicity; Glioma; HeLa Cells; Histones; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mutant Proteins; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; S Phase; Survival Analysis

2017
Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Biocatalysis; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Histones; Humans; Lysine; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Promoter Regions, Genetic; Retinoblastoma-Binding Protein 2; Zinc Finger E-box-Binding Homeobox 1

2018
Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.
    Cancer letters, 2018, 04-10, Volume: 419

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glioma; Histones; Humans; Lysine; Methylation; Mice, Nude; Temozolomide; X-linked Nuclear Protein; Xenograft Model Antitumor Assays

2018
Methylation-induced downregulation and tumor-suppressive role of microRNA-98 in glioma through targeting Sal-like protein 4.
    International journal of molecular medicine, 2018, Volume: 41, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Transcription Factors; Young Adult

2018
In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging.
    Clinical neuroradiology, 2019, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Brain Neoplasms; Cerebral Blood Volume; Chromosome Deletion; Chromosomes, Human, 1-3; Contrast Media; Cross-Sectional Studies; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Profiling; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Angiography; Methylation; Middle Aged; Mutation; Retrospective Studies; Tumor Suppressor Proteins; X-linked Nuclear Protein; Young Adult

2019
Methylation of PD-1 Promoter Gene as New Prognostic Marker for IDH Mutant Low-Grade Glioma?
    EBioMedicine, 2018, Volume: 29

    Topics: Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Prognosis; Programmed Cell Death 1 Receptor

2018
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M
    Nature medicine, 2018, Volume: 24, Issue:5

    Topics: Animals; Brain Neoplasms; Gangliosides; Glioma; Histones; Humans; Immunotherapy, Adoptive; Lysine; Methylation; Mice; Receptors, Antigen, T-Cell; Xenograft Model Antitumor Assays

2018
Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.
    Journal of cell science, 2018, 06-21, Volume: 131, Issue:12

    Topics: Brain Stem Neoplasms; Cell Line; Chromatin; DNA End-Joining Repair; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Genomic Instability; Glioma; HEK293 Cells; Histones; Humans; Methylation; Tumor Suppressor p53-Binding Protein 1

2018
H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.
    eLife, 2018, 06-22, Volume: 7

    Topics: Brain Stem Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cellular Reprogramming; Enhancer Elements, Genetic; Epigenomics; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Methylation; Mutation; Neuroglia; Polycomb-Group Proteins; Promoter Regions, Genetic; WT1 Proteins

2018
Survival gain with re-Op/RT for recurred high-grade gliomas depends upon risk groups.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioma; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Promoter Regions, Genetic; Radiotherapy, Adjuvant; Reoperation; Retreatment; Retrospective Studies; Risk Factors; Tumor Suppressor Proteins

2018
Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 09-18, Volume: 115, Issue:38

    Topics: Carcinogenesis; Cell Line, Tumor; Child; DNA Mismatch Repair; Genomic Instability; Glioma; Glycine; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mutation; MutS DNA Mismatch-Binding Protein; Protein Binding; Protein Processing, Post-Translational

2018
HMGB1 contributes to SASH1 methylation to attenuate astrocyte adhesion.
    Cell death & disease, 2019, 05-28, Volume: 10, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Astrocytes; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Ontology; Glioma; HMGB1 Protein; Integrin beta Chains; Methylation; Rats; RNA-Seq; Tumor Suppressor Proteins

2019
Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma.
    Cell death & disease, 2019, 06-06, Volume: 10, Issue:6

    Topics: Animals; beta Catenin; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glioma; Glycogen Synthase Kinases; Histones; Humans; Methylation; Mice; Mice, Nude; MicroRNAs; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Prognosis; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous

2019
H3.3K27M-induced chromatin changes drive ectopic replication through misregulation of the JNK pathway in C. elegans.
    Nature communications, 2019, 06-07, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carcinogenesis; Cell Cycle; Chromatin; DNA Replication; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Germ Cells; Glioma; Heterochromatin; Histone Code; Histones; MAP Kinase Signaling System; Methylation; Polycomb Repressive Complex 2

2019
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.
    Acta neuropathologica, 2013, Volume: 125, Issue:5

    Topics: Adolescent; Adult; Age Factors; Brain Neoplasms; Case-Control Studies; Child; Cohort Studies; Exome; Glioma; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Methylation; Middle Aged; Mutation; Neoplasm Grading; Young Adult

2013
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
    Science (New York, N.Y.), 2013, May-03, Volume: 340, Issue:6132

    Topics: Animals; Benzeneacetamides; Cell Differentiation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glutarates; Histones; Imidazoles; Isocitrate Dehydrogenase; Methylation; Mice; Mice, SCID; Mutant Proteins; Protein Multimerization; RNA Interference; Xenograft Model Antitumor Assays

2013
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.
    Genes & development, 2013, May-01, Volume: 27, Issue:9

    Topics: Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genome, Human; Glioma; Histones; Humans; Methylation; Mutation; Tumor Cells, Cultured

2013
High grade glioma--the arrival of the molecular diagnostic era for patients over the age of 65 years in the UK.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2013, Volume: 25, Issue:7

    Topics: Age Factors; Aged; Brain Neoplasms; Glioma; Humans; Methylation; Molecular Diagnostic Techniques; Molecular Targeted Therapy; Neoplasm Grading; United Kingdom

2013
PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65.
    Nature communications, 2013, Volume: 4

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Brain Neoplasms; DNA-Binding Proteins; Glioma; HEK293 Cells; HeLa Cells; Humans; Immunohistochemistry; Lysine; Methylation; Models, Biological; Phosphorylation; Protein Binding; Protein Phosphatase 2; Signal Transduction; Transcription Factor RelA; Transcription Factors; Tumor Necrosis Factor-alpha

2013
TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas.
    Acta neuropathologica, 2013, Volume: 126, Issue:6

    Topics: Adult; Brain Neoplasms; Glioma; Humans; Methylation; Mutation; Promoter Regions, Genetic; Telomerase; Up-Regulation

2013
Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells.
    Molecular and cellular biochemistry, 2014, Volume: 394, Issue:1-2

    Topics: AC133 Antigen; Antigens, CD; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplastic Stem Cells; Peptides; Promoter Regions, Genetic; Quinazolines; Signal Transduction; SOXB1 Transcription Factors; Transfection

2014
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
    Science (New York, N.Y.), 2014, Aug-29, Volume: 345, Issue:6200

    Topics: Amino Acid Substitution; Animals; Chromatin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Silencing; Glioma; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methionine; Methylation; Mutation; Signal Transduction

2014
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
    Nature medicine, 2014, Volume: 20, Issue:12

    Topics: Animals; Apoptosis; Benzazepines; Brain Stem Neoplasms; Cell Line, Tumor; Cell Proliferation; Child; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Pyrimidines; Xenograft Model Antitumor Assays

2014
Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electron Transport Complex I; Glioma; Humans; Male; Methylation; Mitochondria; Promoter Regions, Genetic; Rats, Sprague-Dawley; Tamoxifen; Temozolomide; Tumor Suppressor Proteins

2015
[Aberrant expression of sox2 gene in malignant gliomas].
    Tsitologiia, 2014, Volume: 56, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Methylation; Primary Cell Culture; Protein Processing, Post-Translational; SOXB1 Transcription Factors; Tumor Microenvironment

2014
Methylation of the miR-126 gene associated with glioma progression.
    Familial cancer, 2016, Volume: 15, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Case-Control Studies; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Glioma; Humans; Male; Methylation; MicroRNAs; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2016
Effect of α-Methyl versus α-Hydrogen Substitution on Brain Availability and Tumor Imaging Properties of Heptanoic [F-18]Fluoroalkyl Amino Acids for Positron Emission Tomography (PET).
    Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7

    Topics: Amino Acid Substitution; Amino Acids; Amino Acids, Neutral; Animals; Biological Transport; Brain; Brain Neoplasms; Fluorine Radioisotopes; Glioma; Hydrogen; Male; Methylation; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Tyrosine

2016
Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Astrocytes; Benzeneacetamides; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Glioma; Glutarates; Histones; Humans; Imidazoles; Isocitrate Dehydrogenase; Methylation; Mutation

2016
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.
    Nature medicine, 2017, Volume: 23, Issue:4

    Topics: Acetylation; Animals; Azepines; Brain Stem Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Epigenomics; Gene Expression Regulation, Neoplastic; Glioma; Histone Code; Histones; Humans; Methylation; Mice; Molecular Targeted Therapy; Mutation; Neurogenesis; Nucleosomes; Polycomb Repressive Complex 2; Protein Transport; RNA-Binding Proteins; Triazoles; Xenograft Model Antitumor Assays

2017
Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.
    Bioorganic & medicinal chemistry, 2008, Jul-01, Volume: 16, Issue:13

    Topics: Cell Line; Cell Survival; Dronabinol; Glioma; Humans; Methylation; Molecular Structure; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship

2008
Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site.
    Glia, 2009, Volume: 57, Issue:9

    Topics: Acetylation; Animals; Binding Sites; Brain; Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Female; Glioma; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Immunoglobulins; Membrane Proteins; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; p300-CBP Transcription Factors; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA; Sp1 Transcription Factor

2009
Redox dependence and compartmentation of [13C]pyruvate in the brain of deuterated rats bearing implanted C6 gliomas.
    Journal of neurochemistry, 2009, Volume: 109 Suppl 1

    Topics: Animals; Astrocytes; Brain Chemistry; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Cerebral Cortex; Deuterium; Glioma; Glucose; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methylation; Neoplasm Transplantation; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar

2009
Chk2 down-regulation by promoter hypermethylation in human bulk gliomas.
    Life sciences, 2010, Jan-30, Volume: 86, Issue:5-6

    Topics: Brain; Cell Line, Tumor; Checkpoint Kinase 2; Chromatin Immunoprecipitation; DNA Damage; Down-Regulation; Genes, Reporter; Glioma; Humans; Luciferases, Firefly; Luciferases, Renilla; Methylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Transfection

2010
Retrospective protein expression and epigenetic inactivation studies of CDH1 in patients affected by low-grade glioma.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Adolescent; Adult; Aged; Antigens, CD; Brain Neoplasms; Cadherins; Disease-Free Survival; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Ki-67 Antigen; Male; Methylation; Middle Aged; Retrospective Studies; Statistics, Nonparametric; Young Adult

2011
Aberrant hypermethylation of non-promoter zygote arrest 1 (ZAR1) in human brain tumors.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:12

    Topics: Astrocytoma; Brain; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Egg Proteins; Glioblastoma; Glioma; Humans; Mass Spectrometry; Melanoma; Methylation; Nevus; Oligodendroglioma; Pituitary Neoplasms; Reference Values

2010
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
    Nature, 2012, Feb-15, Volume: 483, Issue:7390

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Astrocytes; Cell Differentiation; Cell Line, Tumor; Cell Lineage; DNA Methylation; Enzyme Induction; Gene Expression Regulation; Glioma; Glutarates; HEK293 Cells; Histones; Humans; Isocitrate Dehydrogenase; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Mutation; Neural Stem Cells; Promoter Regions, Genetic

2012
The role of protein arginine-methyltransferase 1 in gliomagenesis.
    BMB reports, 2012, Volume: 45, Issue:8

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Glioma; Histones; Humans; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous; Up-Regulation

2012
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
    Neuroscience letters, 2012, Oct-24, Volume: 528, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Decitabine; Down-Regulation; Epigenesis, Genetic; Gene Silencing; Glioma; Humans; Methylation; MicroRNAs; Neoplastic Stem Cells; Promoter Regions, Genetic; Temozolomide

2012
Distinct methylation profiles of glioma subtypes.
    International journal of cancer, 2003, Aug-10, Volume: 106, Issue:1

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; CpG Islands; Female; Glioblastoma; Glioma; Humans; Infant; Male; Methylation; Middle Aged; Oligodendroglioma; Prognosis; Sulfites

2003
Tumour necrosis and microvascular proliferation are associated with 9p deletion and CDKN2A alterations in 1p/19q-deleted oligodendrogliomas.
    Neuropathology and applied neurobiology, 2003, Volume: 29, Issue:5

    Topics: Central Nervous System Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 9; Gene Deletion; Genes, p16; Glioma; Humans; Loss of Heterozygosity; Methylation; Microsatellite Repeats; Necrosis; Oligodendroglioma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic

2003
Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.
    DNA research : an international journal for rapid publication of reports on genes and genomes, 2004, Feb-29, Volume: 11, Issue:1

    Topics: Alleles; Animals; Base Sequence; Brain Neoplasms; Chromosomes, Human, Pair 19; Expressed Sequence Tags; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Kruppel-Like Transcription Factors; Methylation; Mice; Molecular Sequence Data; Polymorphism, Single Nucleotide; Protein Kinases; Transcription Factors; Tumor Cells, Cultured

2004
Hypermethylation of the RASSF1A gene in gliomas.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 349, Issue:1-2

    Topics: Adolescent; Adult; Aged; Apoptosis Regulatory Proteins; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p16; Death-Associated Protein Kinases; DNA, Complementary; Female; Gene Expression; Gene Frequency; Genes, Tumor Suppressor; Glioma; Humans; Male; Methylation; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; Tumor Suppressor Proteins

2004
Expression and activity of l-isoaspartyl methyltransferase decrease in stage progression of human astrocytic tumors.
    Brain research. Molecular brain research, 2005, Apr-27, Volume: 135, Issue:1-2

    Topics: Animals; Blotting, Northern; Brain; Brain Neoplasms; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioma; Humans; Immunohistochemistry; Male; Methylation; Neoplasm Transplantation; Phosphopyruvate Hydratase; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity.
    Biochemical and biophysical research communications, 2006, Jun-09, Volume: 344, Issue:3

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Glioma; Humans; Methylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Radiation Dosage; Radiation Tolerance; Radiation, Ionizing; Tumor Suppressor Proteins

2006
Expression of cellular adhesion molecule 'OPCML' is down-regulated in gliomas and other brain tumours.
    Neuropathology and applied neurobiology, 2007, Volume: 33, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; DNA, Complementary; Down-Regulation; Exons; Gene Expression Regulation, Neoplastic; Glioma; GPI-Linked Proteins; Humans; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm

2007
Hypomethylation of DNA in human cancer cells: a site-specific change in the c-myc oncogene.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:5

    Topics: Base Sequence; Cell Line; DNA Restriction Enzymes; DNA, Neoplasm; Glioma; Humans; Lung Neoplasms; Melanoma; Methylation; Neoplasms; Oncogenes

1984
Alteration in phospholipid methylation and impairment of signal transmission in persistently paramyxovirus-infected C6 rat glioma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:12

    Topics: Adenylyl Cyclases; Animals; Cell Line; Enzyme Activation; Glioma; Membrane Lipids; Methylation; Phosphatidylethanolamines; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Respirovirus Infections

1982
Methylation-related chromatin structure is associated with exclusion of transcription factors from and suppressed expression of the O-6-methylguanine DNA methyltransferase gene in human glioma cell lines.
    Molecular and cellular biology, 1994, Volume: 14, Issue:10

    Topics: Base Sequence; Chromatin; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; Gene Expression Regulation, Neoplastic; Glioma; Humans; Methylation; Methyltransferases; Models, Genetic; Molecular Sequence Data; Nervous System Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Protein Binding; Restriction Mapping; Sp1 Transcription Factor; Transcription, Genetic; Tumor Cells, Cultured

1994
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured

1995
Contribution of O6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines.
    Molecular carcinogenesis, 1995, Volume: 13, Issue:2

    Topics: Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug Screening Assays, Antitumor; Ethylnitrosourea; Glioma; Medulloblastoma; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured

1995
C-terminal CTII motif of 2',3'-cyclic nucleotide 3'-phosphodiesterase undergoes carboxylmethylation.
    Journal of neuroscience research, 1994, Dec-01, Volume: 39, Issue:5

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Alkylation; Amino Acid Sequence; Animals; Baculoviridae; Cell Line; Cell-Free System; Glioma; Methylation; Molecular Sequence Data; Myelin Sheath; Nerve Tissue Proteins; Oligodendroglia; Phosphoric Diester Hydrolases; Protein Prenylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Spodoptera; Tumor Cells, Cultured

1994
Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells.
    The Journal of biological chemistry, 1994, Jun-24, Volume: 269, Issue:25

    Topics: Base Sequence; Cell Nucleus; DNA Primers; Gene Expression Regulation, Enzymologic; Genes; Glioma; Humans; Introns; Methylation; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Tumor Cells, Cultured

1994
Human blood group B-active ganglio-glycosphingolipid in rat glioma.
    Biochimica et biophysica acta, 1993, Sep-29, Volume: 1170, Issue:1

    Topics: ABO Blood-Group System; Animals; Carbohydrate Sequence; Cell Line; Fatty Acids; Glioma; Glycoside Hydrolases; Glycosphingolipids; Humans; Magnetic Resonance Spectroscopy; Methylation; Molecular Sequence Data; Rats; Spectrometry, Mass, Fast Atom Bombardment

1993
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Astrocytoma; Azacitidine; Base Sequence; Brain Chemistry; Brain Neoplasms; Carrier Proteins; Chromatin; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1996
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.
    Cancer research, 1996, Feb-15, Volume: 56, Issue:4

    Topics: Adult; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cell Line; Child; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 9; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Dinucleoside Phosphates; DNA; DNA, Neoplasm; Female; Genes, Tumor Suppressor; Glioma; Homozygote; Humans; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphocytes; Male; Methylation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Reference Values; Restriction Mapping; Tumor Cells, Cultured; Tumor Suppressor Proteins

1996
Alteration of c-fos gene methylation in human gliomas.
    Molecular carcinogenesis, 1996, Volume: 16, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cytosine; DNA, Neoplasm; Exons; Female; Genes, fos; Glioma; Humans; Introns; Male; Methylation; Middle Aged; RNA, Messenger; Tumor Cells, Cultured

1996
Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene.
    The Journal of biological chemistry, 1996, Jun-07, Volume: 271, Issue:23

    Topics: Base Sequence; Binding Sites; CpG Islands; Cytosine; DNA, Neoplasm; Gene Expression; Genetic Linkage; Glioma; Humans; Methylation; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured; X Chromosome

1996
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:9

    Topics: Adult; Aged; Brain Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Neoplasm; Female; Gene Deletion; Genes, p53; Genes, Tumor Suppressor; Glioma; Humans; Male; Methylation; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Tumor Cells, Cultured; Tumor Suppressor Proteins

1996
Hypermethylation of the CpG island of p16/CDKN2 correlates with gene inactivation in gliomas.
    Oncogene, 1996, Oct-17, Volume: 13, Issue:8

    Topics: Brain Neoplasms; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p16; Dinucleoside Phosphates; Down-Regulation; Glioma; Humans; Immunohistochemistry; Methylation

1996
In vivo observation of lactate methyl proton magnetization transfer in rat C6 glioma.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:4

    Topics: Animals; Glioma; Lactates; Magnetic Resonance Spectroscopy; Male; Methylation; Models, Theoretical; Rats; Rats, Inbred F344

1999
Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene.
    Molecular and cellular biology, 1990, Volume: 10, Issue:6

    Topics: Animals; Base Sequence; Cell Line; Cell Nucleus; Enhancer Elements, Genetic; Gene Expression; Glioma; Humans; Interleukin-1; Interleukin-6; L Cells; Methylation; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Sequence Homology, Nucleic Acid; Transcription, Genetic; Transfection

1990
The effect of polar head group substitution on phospholipid methylation and the beta-adrenergic response in C6 glial cells.
    The Biochemical journal, 1985, Nov-01, Volume: 231, Issue:3

    Topics: Animals; Cell Line; Cell Membrane; Cyclic AMP; Glioma; Isoproterenol; Methylation; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats

1985
Cellular resistance to chloroethylnitrosoureas, nitrogen mustard, and cis-diamminedichloroplatinum(II) in human glial-derived cell lines.
    Cancer research, 1987, Mar-01, Volume: 47, Issue:5

    Topics: Carmustine; Cell Line; Cell Survival; Cisplatin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Glioma; Humans; Mechlorethamine; Methylation; Nimustine; Nitrosourea Compounds; Sister Chromatid Exchange

1987
Biochemical patterns in brain tumours. 3. Transfer ribonucleic acid.
    Acta neurochirurgica, 1969, Volume: 21, Issue:2

    Topics: Astrocytoma; Biological Transport; Brain Chemistry; Brain Neoplasms; Glioma; Humans; Medulloblastoma; Methylation; Nucleosides; RNA, Neoplasm; Spectrophotometry

1969
Transfer and ribosomal ribonucleic acids in brain tumors.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Brain Neoplasms; Glioma; Humans; Methylation; Ribosomes; RNA, Neoplasm; RNA, Transfer

1971