isomethyleugenol has been researched along with Genome Instability in 74 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 13 (17.57) | 29.6817 |
2010's | 47 (63.51) | 24.3611 |
2020's | 14 (18.92) | 2.80 |
Authors | Studies |
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Chiang, K; Choi, SY; Davies, CC; Dreveny, I; Dufficy, ER; Gunnell, E; Maslen, S; McNee, GS; Sahay, D; Sanchez-Bailon, MP; Sharma, K; Skehel, JM; Stewart, GS | 1 |
Chen, ES; Lam, UTF | 1 |
Yao, S; Yin, T; Zhao, L | 1 |
Alarcon, EI; Arvanitis-Vigneault, A; Brunzelle, JS; Couture, JF; Davarinejad, H; Dong, J; Huang, YC; Jacob, Y; Joly, V; LeBlanc, C; Mermaz, B; Muñoz, M; Poulet, A; Ross, A; Rotstein, BH; Thomson, G; Valsakumar, D; Villarino, G; Voigt, P | 1 |
Coin, F; Gsell, C; Naegeli, H; Richly, H | 1 |
Biggins, S; Chong, SY; Cutler, S; Kao, CF; Lin, JJ; Lo, YC; Tsai, CH; Tsai, HK; Tsukiyama, T | 1 |
Anlaş, AA; Nelson, CM | 1 |
Mattiroli, F; Penengo, L | 1 |
Dere, R; Young, NL | 1 |
Dong, J; Jacob, Y; Joly, V; LeBlanc, C; Mendez, J; Mermaz, B; Poulet, A; Villarino, G; Voigt, P; Webb, KM | 1 |
Aladjem, MI; Burkett, S; Ding, X; Finney, R; He, Y; Liu, Y; Muegge, K; Ni, K; Ren, J; Sharan, SK; Sun, C; Xu, X | 1 |
Cardoso, MC; Casas-Delucchi, CS; Coster, G; Daiß, JL; Engel, C; Hastert, FD; Rausch, C; Weber, P; Zhang, P | 1 |
Altaf, M; Bhat, A; Hunt, CR; Mir, US; Mushtaq, A; Pandita, RK; Pandita, S; Pandita, TK; Tantray, WW | 1 |
Alvarez, NS; Basu, U; Ding, L; Hanna, JH; Jha, MK; Laffleur, B; Lee, H; Lim, J; Liu, ZP; Munteanu, EL; Nair, L; Rothschild, G; Swayne, T; Wu, L; Zhang, W | 1 |
Fukuda, K; Go, Y; Ichiyanagi, K; Ichiyanagi, T; Imai, H; Inoguchi, Y; Nagano, M; Ohkawa, Y; Sasaki, H; Takaesu, N; Yanagawa, Y | 1 |
Alag, N; Arnott, D; Chen, KB; Classon, M; Cuellar, T; Giresi, PG; Guler, GD; Haley, B; Hegde, G; Jackson, E; Jhunjhunwala, S; KaiWai Cheung, T; Kim, HJ; Liu, J; Nance, TL; Nichols, K; Pitti, R; Settleman, J; Stephan, JP; Tindell, CA; Webster, J; Wilson, C; Wongchenko, M; Yan, Y | 1 |
Ceccaldi, R; D'Andrea, AD; Duarte, AA; Gogola, E; Jonkers, J; Konstantinopoulos, PA; Rondinelli, B; Rottenberg, S; van de Ven, M; van der Sluijs, R; Yücel, H | 1 |
Chiang, YC; Chowdhury, P; Davis, IJ; de Cubas, AA; Dere, R; Fahey, CC; Karki, M; Khan, A; Mason, FM; Ohi, R; Park, IY; Parker, JS; Powell, RT; Rathmell, WK; Shuster, CB; Sohn, BH; Strahl, BD; Terzo, EA; Tripathi, DN; Tsai, YS; Walker, CL | 1 |
Chang, JF; Chen, L; He, ZM; Jiang, CZ; Jing, YY; Kang, X; Liu, KN; Mao, ZY; Shen, Y; Sun, FL; Sun, J; Tang, HY; Wang, C; Wang, DL; Wei, HM; Wu, JY; Xu, RG; Yang, XM; Zeng, SY; Zhang, Y; Zhu, RB | 1 |
Fang, J; Gu, L; Huang, Y; Li, GM; Li, H; Mao, G; Rennert, G; Yang, S | 1 |
Braun, S; Brönner, C; Capella, M; Fischer-Burkart, S; Forn, M; Forné, I; Halic, M; Imhof, A; Martín Caballero, L; Sarkadi, Z; Simonetta, M; Toczyski, D; van Emden, TS | 1 |
Barco, A; Scandaglia, M | 1 |
Connolly, LR; Freitag, M; Happ, K; Happel, P; Haueisen, J; Möller, M; Schotanus, K; Smith, KM; Soyer, JL; Stralucke, M; Stukenbrock, EH | 1 |
Beck, DB; Dooley, SJ; Fondevila, D; Kane-Goldsmith, N; Krüger, M; Marazuela-Duque, A; Martínez-Redondo, P; Muñoz, P; Rabanal, RM; Serrano, L; Tischfield, JA; Tong, Q; Vaquero, A; Vazquez, BN; Voigt, P | 1 |
Dong, A; Feng, H; Shen, WH; Yao, X; Yu, Y | 1 |
Bin, P; Chen, W; Cheng, J; Dai, Y; Dong, H; Duan, H; He, Z; Lin, H; Ma, J; Niu, Y; Sheng, Z; Xiao, Y; Zhang, B; Zheng, Y; Zhu, B | 1 |
Davie, JR; Guppy, BJ; McManus, KJ; Sawchuk, L; Thompson, LL | 1 |
Aladjem, MI; Fu, H; Huang, L; Kim, R; Lin, CM; Martin, MM; Maunakea, AK; Ryan, M; Zhang, Y; Zhao, K | 1 |
Allis, CD; Black, JC; Cho, J; Daniels, DL; Dyson, NJ; Getz, G; Glass, K; Kim, J; Ladd, B; Lewis, PW; Manning, AL; Montagna, C; Murphy, N; Pineda, CM; Van Rechem, C; Whetstine, JR | 1 |
Chen, D; Hu, L; Lin, G; Liu, L; Lu, G; Ouyang, Q; Sun, Y; Xie, P; Yuan, D; Zeng, S | 1 |
Bedford, MT; Chedin, F; Hensley, S; Lu, Y; McBride, KM; Yang, Y | 1 |
Gao, J; Li, X; Liang, J; Liu, L; Shan, L; Shang, Y; Shi, L; Song, N; Wang, Q; Wang, Y; Xuan, C; Yang, S; Yu, N; Zhou, X | 1 |
Ahrabi, S; Aymard, F; Bachrati, CZ; Helleday, T; Humphrey, TC; La Thangue, NB; Legube, G; Pfister, SX; Porter, AC; Sarkar, S; Zalmas, LP | 1 |
Kovalchuk, I; Kovalchuk, O; Li, D; Sidler, C; Wang, B; Woycicki, R | 1 |
Cheng, Z; Cheung, P; Gozani, O; Kuo, AJ; Patel, DJ; Wilmot, CM; Yukl, ET | 1 |
Hakim, O; Jailwala, P; Khurana, S; Kim, J; Kruhlak, MJ; Liu, J; Nyswaner, K; Oberdoerffer, P; Shi, L; Sung, MH; Tran, AD | 1 |
Guppy, BJ; McManus, KJ | 1 |
Clouaire, T; Legube, G | 1 |
Allis, CD; Banaszynski, LA; Diaz, N; Elsässer, SJ; Noh, KM | 1 |
Coulombe, Y; Gurunathan, G; Masson, JY; Richard, S; Yu, Z | 1 |
Bahar, I; Fujita, N; Gamper, A; Gur, M; Hu, D; Hung, MC; Lan, L; Wan, Y; Zhou, Z | 1 |
Amin, SB; Antonini, E; Chin, L; Cittaro, D; Di Croce, L; Frenquelli, M; Futreal, PA; Huang, D; Lazarevic, D; Montanini, L; Rondinelli, B; Rosano, D; Segalla, S; The, BT; Tonon, G; Verhaak, RG; Yoshihara, K | 1 |
Bawa-Khalfe, T; Cheng, J; Chin, YE; Huang, C; Yao, X; Yeh, ETH | 1 |
Armstrong, RL; Duronio, RJ; Li, Y; MacAlpine, DM | 1 |
Alabert, C; Bartke, T; Bekker-Jensen, S; Cejka, P; Forne, I; Foster, BM; Groth, A; Hammond, CM; Huang, H; Imhof, A; Mailand, N; Mlejnkova, L; Patel, DJ; Reverón-Gómez, N; Saredi, G | 1 |
Jin, M; Meng, L; Sun, H; Wang, B; Wang, H; Wang, J; Wang, Y; Xu, C; Zhang, Y; Zhu, T | 1 |
Bedford, MT; Blasius, TL; Chiang, YC; Davis, IJ; Dere, R; Fahey, CC; Hacker, KE; Ho, TH; Jonasch, E; Park, IY; Powell, RT; Rathmell, WK; Tripathi, DN; Verhey, KJ; Walker, CL | 1 |
Giaccia, AJ | 1 |
Liu, T; Tan, H; Zhang, J; Zhou, T | 1 |
Algire, MA; Arrowsmith, CH; Barsyte-Lovejoy, D; Bromberg, KD; Brown, PJ; Chiang, GG; Comess, KM; Dai, Y; Eram, MS; Jakob, CG; Jhala, MA; Lasko, LM; Li, C; Li, F; Manaves, V; Martin, A; Michaelides, MR; Mitchell, TR; Nuber, A; Pappano, WN; Rice, JC; Santhakumar, V; Schotta, G; Shoemaker, AR; Soni, NB; Sun, C; Sweis, RF; Torrent, M; Tuzon, CT; Upadhyay, AK; Vedadi, M | 1 |
Chen, E; Gu, SG; Kalinava, N; Ni, JZ; Peterman, K | 1 |
Bandeiras, TM; Chiang, K; Clarke, TL; Davies, CC; Herrero-Ruiz, J; Maslen, SL; Matias, PM; Reynolds, JJ; Sanchez-Bailon, MP; Skehel, JM; Stewart, GS | 1 |
Arida, AR; Greeson, NT; Jenuwein, T; Sanders, SL; Sengupta, R | 1 |
Kumar, R; Misri, S; Pandita, S; Pandita, TK | 1 |
Muñoz, IM; Rouse, J | 1 |
Chen, T; Hébert, J; Li, E; Richard, S; Yu, Z | 1 |
Karpen, GH; Peng, JC | 1 |
Jiang, G; Willers, H; Xia, F; Zhuang, J | 1 |
Chandrasekharan, MB; Huang, F; Sun, ZW | 1 |
Fok, AK; Kobor, MS; Leung, GP; Lévesque, N; Schmidt, TI | 1 |
Brown, EJ; Cheng, EH; Hsieh, JJ; Kumar, R; Liu, H; Pandita, TK; Takeda, S; Westergard, TD | 1 |
Centore, RC; Dyson, NJ; Flynn, RL; Havens, CG; Jin, J; Li, JM; Manning, AL; Tse, A; Walter, JC; Zou, L | 1 |
Farina, A; Gurvich, N; Hurwitz, J; Menendez, S; Nimer, SD; Perna, F; Voza, F | 1 |
Feng, J; Maze, I; Nestler, EJ; Shen, L; Sun, H; Wilkinson, MB | 1 |
Cordonier, EL; Li, Y; Xue, J; Zempleni, J | 1 |
Chu, A; Glazer, PM; Lu, Y; Turker, MS | 1 |
Jørgensen, S; Schotta, G; Sørensen, CS | 1 |
Hirai, Y; Takeshima, N | 1 |
Inoue, M; Kanaya, T; Kyo, S; Maida, Y | 1 |
Anacleto, C; Caballero, O; Camargo, AA; Leopoldino, AM; Lopes, A; Pena, SD; Rocha, JC; Rossi, B; Simpson, AJ; Soares, FA | 1 |
Bodmer, WF | 1 |
Caikovski, M; Mathieu, O; Paszkowski, J; Reinders, J; Smathajitt, C | 1 |
Herceg, Z; Julien, E; Murr, R; Sardet, C; Tardat, M | 1 |
Asim, M; Basir, SF; Chauhan, M; Deo, SS; Husain, SA; Hussain, A; Kukreti, H; Naqvi, RA; Pasha, ST; Sarin, R; Saxena, A; Shukla, NK | 1 |
13 review(s) available for isomethyleugenol and Genome Instability
Article | Year |
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Molecular mechanisms in governing genomic stability and tumor suppression by the SETD2 H3K36 methyltransferase.
Topics: Animals; Carcinogenesis; Chromatin; Genomic Instability; Histones; Humans; Lysine; Mammals; Methylation; Neoplasms | 2022 |
Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability.
Topics: Animals; DNA Damage; DNA Repair; Genomic Instability; Histones; Humans; Methylation; Phosphorylation; Ubiquitin; Ubiquitination | 2021 |
Mechanistic insights into KDM4A driven genomic instability.
Topics: Animals; Cell Transformation, Neoplastic; Genomic Instability; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction | 2021 |
Role of Histone Methylation in Maintenance of Genome Integrity.
Topics: Animals; DNA Repair; Genomic Instability; Histone Code; Histones; Humans; Methylation | 2021 |
Contribution of spurious transcription to intellectual disability disorders.
Topics: Chromatin; Chromatin Assembly and Disassembly; DNA Methylation; Ectopic Gene Expression; Epigenesis, Genetic; Genetic Association Studies; Genetic Predisposition to Disease; Genomic Instability; Histones; Humans; Intellectual Disability; Methylation; Mutation; Neurons; Transcription, Genetic | 2019 |
Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; DNA Repair; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Genomic Instability; Histone Demethylases; Histones; Humans; Interphase; Methylation; Mitosis; Neoplasms; Phosphorylation; Prognosis; Protein Processing, Post-Translational; Transcriptome; Ubiquitination | 2013 |
Telomeres, histone code, and DNA damage response.
Topics: Acetylation; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Chromatin; DNA Damage; DNA-Binding Proteins; Genomic Instability; Histones; Humans; Methylation; Phosphorylation; Protein Serine-Threonine Kinases; Radiation, Ionizing; Telomere; Tumor Suppressor Proteins; Ubiquitin | 2008 |
Control of histone methylation and genome stability by PTIP.
Topics: Animals; Carrier Proteins; DNA Damage; DNA-Binding Proteins; Gene Expression Regulation; Genomic Instability; Histones; Methylation; Mice; Nuclear Proteins; Promoter Regions, Genetic; Signal Transduction | 2009 |
Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.
Topics: Chromatin Assembly and Disassembly; Genomic Instability; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Models, Biological; Models, Molecular; Nucleosomes; Protein Processing, Post-Translational; Ubiquitination | 2010 |
Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity.
Topics: Animals; Cell Cycle; Chromatin; DNA Damage; DNA Replication; Epigenesis, Genetic; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Methylation; Tumor Suppressor p53-Binding Protein 1 | 2013 |
[Genetic abnormalities in endometrial cancer].
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Carrier Proteins; Cell Division; Endometrial Neoplasms; Female; Gene Silencing; Genes, p53; Genes, Tumor Suppressor; Genomic Instability; Humans; Loss of Heterozygosity; Methylation; Microsatellite Repeats; Mutation; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Promoter Regions, Genetic; PTEN Phosphohydrolase; Signal Transduction; Tumor Suppressor Proteins | 2004 |
[Genetic diagnosis of endometrial cancer].
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; DNA Repair; Endometrial Neoplasms; Female; Genomic Instability; Humans; Methylation; Microsatellite Repeats; Mutation; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Promoter Regions, Genetic; PTEN Phosphohydrolase; Sequence Analysis, DNA; Telomerase; Tumor Suppressor Proteins | 2004 |
Cancer genetics: colorectal cancer as a model.
Topics: Adenoma; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Epigenesis, Genetic; Genetic Variation; Genomic Instability; Homeodomain Proteins; Humans; Methylation; Models, Biological; Models, Genetic | 2006 |
61 other study(ies) available for isomethyleugenol and Genome Instability
Article | Year |
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Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.
Topics: Arginine; Cell Line; DNA Damage; Genomic Instability; Humans; Methylation; MRE11 Homologue Protein; Protein-Arginine N-Methyltransferases; Rad51 Recombinase; Recombinational DNA Repair; Repressor Proteins; Thiolester Hydrolases; Ubiquitination | 2021 |
Comprehensive characterization of m6A methylation and its impact on prognosis, genome instability, and tumor microenvironment in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Genomic Instability; Humans; Liver Neoplasms; Methylation; Prognosis; Tumor Microenvironment | 2022 |
The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
Topics: Arabidopsis; Arabidopsis Proteins; DNA Breaks, Double-Stranded; DNA Polymerase theta; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; DNA, Plant; Genome, Plant; Genomic Instability; Histones; Lysine; Methylation; Methyltransferases; Mutation; Protein Interaction Domains and Motifs | 2022 |
A chromatin scaffold for DNA damage recognition: how histone methyltransferases prime nucleosomes for repair of ultraviolet light-induced lesions.
Topics: Chromatin; DNA Damage; DNA Repair; Genomic Instability; Histone Methyltransferases; Histones; Methylation; Nucleosomes; Saccharomyces cerevisiae; Signal Transduction; Ultraviolet Rays | 2020 |
H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress.
Topics: Cell Cycle Proteins; Checkpoint Kinase 2; Chromatin; DNA Polymerase II; DNA Replication; Genome, Fungal; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Methylation; Models, Genetic; Mutation; S Phase Cell Cycle Checkpoints; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription, Genetic | 2020 |
Living under Strain: How Epithelia Protect Their Genomes from Repeated Stretching.
Topics: Animals; Cellular Microenvironment; DNA; DNA Damage; Epithelium; Extracellular Matrix; Genome; Genomic Instability; Histones; Humans; Lysine; Methylation; Stem Cells; Stress, Mechanical | 2020 |
H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation.
Topics: Acetylation; Arabidopsis; Arabidopsis Proteins; Gene Silencing; Genome, Plant; Genomic Instability; Heterochromatin; Histone Acetyltransferases; Histones; Lysine; Methylation; Methyltransferases; Mutation; Plants, Genetically Modified; Transcription Factors | 2021 |
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.
Topics: Animals; BRCA1 Protein; Cell Line, Tumor; Cell Survival; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation Sequencing; DNA Helicases; DNA Repair Enzymes; DNA Replication; Epigenesis, Genetic; Exodeoxyribonucleases; Genomic Instability; Histones; Humans; Methylation; Mice; MRE11 Homologue Protein; Rad51 Recombinase; RNA, Small Interfering; Up-Regulation | 2021 |
Cytosine base modifications regulate DNA duplex stability and metabolism.
Topics: Animals; Base Pairing; Cell Cycle; Cell Line; Cells, Cultured; Cytosine; DNA; DNA Helicases; DNA Replication; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Genomic Instability; HEK293 Cells; Humans; In Situ Hybridization, Fluorescence; Methylation; Mice; Microscopy, Confocal | 2021 |
Mechanism of noncoding RNA-associated N
Topics: Adenosine; Animals; B-Lymphocytes; Cytidine Deaminase; Exosome Multienzyme Ribonuclease Complex; Female; Genomic Instability; HEK293 Cells; Humans; Immunoglobulin Class Switching; Immunoglobulin Heavy Chains; Male; Membrane Proteins; Methylation; Methyltransferases; Mice, Knockout; Recombination, Genetic; RNA 3' End Processing; RNA, Long Noncoding; RNA, Untranslated | 2021 |
Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability.
Topics: Animals; Biological Evolution; CpG Islands; DNA Copy Number Variations; DNA Methylation; Epigenesis, Genetic; Evolution, Molecular; Gene Expression; Genetic Speciation; Genomic Instability; Genomics; Germ Cells; Humans; Macaca; Male; Methylation; Pan troglodytes; Primates; Retroelements; Spermatozoa | 2017 |
Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.
Topics: Animals; Antineoplastic Agents; Chromatin; Drug Resistance, Neoplasm; Epigenetic Repression; Gene Expression Regulation, Neoplastic; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Long Interspersed Nucleotide Elements; Methylation; Mice; Mice, Nude; Mice, SCID; Neoplasms; Stress, Physiological; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.
Topics: Animals; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cell Line; Cell Line, Tumor; DNA Replication; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Enhancer of Zeste Homolog 2 Protein; Female; Genomic Instability; HEK293 Cells; HeLa Cells; Histones; Humans; Methylation; Mice; Mice, Nude; Poly(ADP-ribose) Polymerase Inhibitors | 2017 |
Topics: Animals; Carcinogenesis; Carcinoma, Renal Cell; Cell Line, Tumor; Chromosomes, Human, Pair 3; Fibroblasts; Gene Knockdown Techniques; Genomic Instability; Haploinsufficiency; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney Neoplasms; Kidney Tubules, Proximal; Lysine; Methylation; Mice; Micronuclei, Chromosome-Defective; Microtubules | 2018 |
Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability.
Topics: Brain Stem Neoplasms; Cell Line; Chromatin; DNA End-Joining Repair; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Genomic Instability; Glioma; HEK293 Cells; Histones; Humans; Methylation; Tumor Suppressor p53-Binding Protein 1 | 2018 |
Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction.
Topics: Carcinogenesis; Cell Line, Tumor; Child; DNA Mismatch Repair; Genomic Instability; Glioma; Glycine; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mutation; MutS DNA Mismatch-Binding Protein; Protein Binding; Protein Processing, Post-Translational | 2018 |
Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.
Topics: Genome, Fungal; Genomic Instability; Heterochromatin; Humans; Methylation; Nucleosomes; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Telomere | 2019 |
Destabilization of chromosome structure by histone H3 lysine 27 methylation.
Topics: Ascomycota; Chromosomes, Fungal; Gene Deletion; Genomic Instability; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Repetitive Sequences, Nucleic Acid; Transcriptional Activation | 2019 |
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
Topics: Acetylation; Amino Acid Sequence; Animals; Cell Cycle; Cell Transformation, Neoplastic; Chromatin; DNA Damage; Gene Knockout Techniques; Genomic Instability; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; M Phase Cell Cycle Checkpoints; Methylation; Mice; Mice, Knockout; Mitosis; Protein Binding; Sirtuin 2 | 2013 |
SDG2-mediated H3K4 methylation is required for proper Arabidopsis root growth and development.
Topics: Arabidopsis; Arabidopsis Proteins; Chromatin Assembly and Disassembly; Chromatin Assembly Factor-1; Comet Assay; DNA Damage; Fluorescent Antibody Technique; Genomic Instability; Histones; Indoleacetic Acids; Lysine; Methylation; Methyltransferases; Microscopy, Confocal; Plant Roots | 2013 |
Global and MGMT promoter hypomethylation independently associated with genomic instability of lymphocytes in subjects exposed to high-dose polycyclic aromatic hydrocarbon.
Topics: Adult; Biomarkers; Blotting, Western; Cells, Cultured; China; Chromosomal Instability; Comet Assay; DNA Damage; DNA Methylation; Genomic Instability; Humans; Lymphocytes; Male; Metallurgy; Methylation; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Occupational Exposure; Polycyclic Compounds; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrenes; Steel; Sulfites | 2013 |
Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.
Topics: Cell Cycle; Chromatin; DNA Replication; Genome, Human; Genomic Instability; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Methyltransferases; Replication Origin; S Phase | 2013 |
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors.
Topics: Chromatin; Chromosomes, Human, Pair 1; DNA Replication; Gene Dosage; Genomic Instability; HEK293 Cells; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Protein Structure, Tertiary; S Phase | 2013 |
Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cells.
Topics: Animals; Biomarkers; Blastocyst; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Embryonic Stem Cells; Genomic Instability; Histones; Humans; Methylation; Mice; Neoplasm Transplantation; Protein Processing, Post-Translational; Telomerase; Telomere; Telomere Homeostasis; Teratoma; Wnt Signaling Pathway | 2014 |
Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.
Topics: Animals; Arginine; Chromatin; DNA Topoisomerases, Type I; Gene Expression Regulation; Genomic Instability; HEK293 Cells; Humans; Methylation; Mice; Mice, Knockout; Protein Transport; Proteins; Proto-Oncogene Proteins c-myc; Transcription, Genetic | 2014 |
Histone demethylase KDM5B is a key regulator of genome stability.
Topics: Antigens, Nuclear; BRCA1 Protein; Cells, Cultured; DNA Damage; DNA Repair; DNA-Binding Proteins; Genomic Instability; HEK293 Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Ku Autoantigen; MCF-7 Cells; Methylation; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Repressor Proteins; RNA, Small Interfering; Signal Transduction | 2014 |
SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.
Topics: DNA Repair; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Homologous Recombination; Humans; Methylation; Protein Binding; Rad51 Recombinase; Recombinational DNA Repair; Transfection | 2014 |
A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts.
Topics: Cell Line; Cellular Senescence; Epigenesis, Genetic; Fibroblasts; Gene Expression Regulation; Genomic Instability; Histones; Humans; Lung; Methylation; Methyltransferases; Piperazines; Repressor Proteins | 2014 |
A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Topics: Animals; Binding Sites; Cell Line; Genomic Instability; Histones; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Models, Molecular; Mutation; Protein Binding; Protein Structure, Quaternary | 2014 |
A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.
Topics: Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; Cell Line, Tumor; Chromatin Assembly and Disassembly; DNA Breaks, Double-Stranded; DNA-Binding Proteins; Genomic Instability; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Nuclear Proteins; Protein Isoforms; Protein Processing, Post-Translational; Protein Transport; Recombinational DNA Repair; Transcription Factors | 2014 |
Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells.
Topics: Cell Cycle; Cell Line; Cytoplasm; Gene Expression; Gene Silencing; Genome, Human; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Methyltransferases; Mitosis; Protein Transport; RNA Interference; RNA, Small Interfering; Ubiquitin-Protein Ligases | 2015 |
DNA double strand break repair pathway choice: a chromatin based decision?
Topics: Chromatin; DNA Breaks, Double-Stranded; DNA Repair; Genomic Instability; Histones; Homologous Recombination; Lysine; Methylation; Models, Biological | 2015 |
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.
Topics: Animals; Carrier Proteins; Cell Line; Co-Repressor Proteins; DNA Helicases; Embryonic Stem Cells; Endogenous Retroviruses; Gene Silencing; Genomic Instability; Heterochromatin; Histones; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Molecular Chaperones; Nuclear Proteins; X-linked Nuclear Protein | 2015 |
Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage.
Topics: Arginine; Cell Cycle Proteins; DNA Damage; DNA-Binding Proteins; Genomic Instability; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Immunoprecipitation; Methylation; Nuclear Proteins; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Repressor Proteins; Transcription Factors | 2015 |
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
Topics: Amino Acid Motifs; Arginine; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Methylation; Protein-Arginine N-Methyltransferases; Ubiquitination | 2015 |
Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.
Topics: Animals; Carcinoma, Renal Cell; Chromobox Protein Homolog 5; DNA-Binding Proteins; Genomic Instability; HeLa Cells; Heterochromatin; Histone Demethylases; Histones; Humans; Kidney Neoplasms; Methylation; Methyltransferases; Mice; Mutation; Neoplasm Proteins; NIH 3T3 Cells; Oxidoreductases, N-Demethylating; Repressor Proteins | 2015 |
SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability.
Topics: Cell Line, Tumor; Centromere; Chromatin Assembly and Disassembly; DNA Repair; G2 Phase; Genomic Instability; Histones; Humans; Methylation; Origin Recognition Complex; Protein Processing, Post-Translational; Retinoblastoma-Binding Protein 2; Small Ubiquitin-Related Modifier Proteins; Sumoylation | 2016 |
Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.
Topics: Animals; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line; DNA Damage; DNA Replication; DNA Replication Timing; Drosophila melanogaster; Drosophila Proteins; Genome, Insect; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Protein Serine-Threonine Kinases; Replication Origin; S Phase | 2016 |
H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.
Topics: Chromatin; DNA Repair; DNA Replication; DNA-Binding Proteins; Genomic Instability; Histones; Homologous Recombination; Humans; Lysine; Methylation; Models, Molecular; Molecular Chaperones; NF-kappa B; Nuclear Proteins; Protein Binding; Protein Structure, Tertiary | 2016 |
DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity.
Topics: Apoptosis; CD8-Positive T-Lymphocytes; DNA Damage; DNA-Activated Protein Kinase; Enhancer of Zeste Homolog 2 Protein; Genomic Instability; Humans; Jurkat Cells; Ku Autoantigen; Mass Spectrometry; Methylation; Phosphorylation; Protein Binding; T-Lymphocytes | 2016 |
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Topics: Cell Line, Tumor; Chromatin Assembly and Disassembly; Cytokinesis; Cytoskeleton; Genomic Instability; Histone Code; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Microtubules; Mitosis; Protein Processing, Post-Translational; Tubulin | 2016 |
A New Chromatin-Cytoskeleton Link in Cancer.
Topics: Chromatin; Cytoskeleton; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tubulin | 2016 |
Random positioning of nucleosomes enhances heritable bistability.
Topics: Algorithms; Chromatin Assembly and Disassembly; Chromosomes; Epigenesis, Genetic; Genomic Instability; Histones; Methylation; Models, Biological; Nucleosomes; Protein Binding | 2016 |
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
Topics: Cell Line, Tumor; Crystallography, X-Ray; DNA Repair; Enzyme Inhibitors; Epigenesis, Genetic; Genomic Instability; Heterocyclic Compounds, 4 or More Rings; Histone-Lysine N-Methyltransferase; Humans; Methylation; Models, Molecular; Molecular Structure | 2017 |
Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Chromatin Immunoprecipitation; Genome; Genomic Instability; Germ Cells; High-Throughput Nucleotide Sequencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Methylation; Microscopy, Fluorescence; Mutagenesis; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Double-Stranded; RNA, Messenger; RNA, Small Interfering; Sequence Analysis, RNA; Transcription, Genetic | 2017 |
PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.
Topics: Acetylation; Animals; Arginine; Ataxia Telangiectasia Mutated Proteins; ATPases Associated with Diverse Cellular Activities; Carrier Proteins; DNA Breaks, Double-Stranded; DNA Helicases; Genomic Instability; HEK293 Cells; HeLa Cells; Histone Acetyltransferases; Histones; Humans; Lysine Acetyltransferase 5; Methylation; Mice; Mice, Transgenic; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinational DNA Repair; RNA Interference; Time Factors; Transfection; Tumor Suppressor p53-Binding Protein 1 | 2017 |
Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage.
Topics: Amino Acid Motifs; Cell Cycle Proteins; Chromatin; DNA Damage; DNA, Fungal; Genome, Fungal; Genomic Instability; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Protein Binding; Protein Methyltransferases; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2008 |
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation.
Topics: Adaptor Proteins, Signal Transducing; Alleles; Animals; Arginine; Cell Proliferation; DNA; DNA Damage; DNA Repair Enzymes; DNA-Binding Proteins; Down-Regulation; Embryo, Mammalian; Etoposide; Female; Fibroblasts; Genome; Genomic Instability; Interphase; Methylation; Mice; Mice, Inbred C57BL; Mitosis; MRE11 Homologue Protein; Protein-Arginine N-Methyltransferases; Rad51 Recombinase; Radiation, Ionizing; RNA-Binding Proteins | 2009 |
Heterochromatic genome stability requires regulators of histone H3 K9 methylation.
Topics: Animals; DNA Damage; DNA Repair; Drosophila; Genomic Instability; Heterochromatin; Histones; Methylation; Methyltransferases; Mitosis; Mutation; RNA Interference | 2009 |
Exonuclease function of human Mre11 promotes deletional nonhomologous end joining.
Topics: Cell Line; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Exonucleases; Genomic Instability; Humans; Methylation; MRE11 Homologue Protein; Mutation; Sequence Deletion | 2009 |
Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA damage sensitivity through the translesion synthesis pathway.
Topics: Chromatin; DNA Damage; DNA Repair; DNA Replication; Endodeoxyribonucleases; Genomic Instability; Histone-Lysine N-Methyltransferase; Intracellular Signaling Peptides and Proteins; Methylation; Mutation; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2010 |
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
Topics: Alleles; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Chromatin; DNA Damage; DNA Replication; Genes, Dominant; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia; Lysine; Methylation; Mice; Myeloid Progenitor Cells; Myeloid-Lymphoid Leukemia Protein; Phosphorylation; Phosphoserine; Protein Binding; Protein Serine-Threonine Kinases; S Phase; S-Phase Kinase-Associated Proteins; Signal Transduction; Translocation, Genetic | 2010 |
CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase.
Topics: Animals; Cell Proliferation; Chromatin Assembly and Disassembly; Cullin Proteins; DNA Damage; DNA Replication; Down-Regulation; Genomic Instability; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mutation; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Protein Binding; Protein Processing, Post-Translational; S Phase; Time Factors; Ubiquitin-Protein Ligases; Ubiquitination; Xenopus | 2010 |
L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.
Topics: Blotting, Western; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Chromosomal Proteins, Non-Histone; Chromosome Deletion; Chromosomes, Human, Pair 20; DNA Damage; DNA Replication; Genomic Instability; HEK293 Cells; Histones; Humans; Immunoprecipitation; K562 Cells; Lysine; Methylation; Myeloproliferative Disorders; Neoplasm Proteins; Protein Binding; Repressor Proteins; Retinoblastoma Protein; RNA Interference; Tumor Suppressor Proteins | 2010 |
Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens.
Topics: Analysis of Variance; Animals; Base Sequence; Blotting, Western; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; DNA Primers; Gene Regulatory Networks; Genomic Instability; Heterochromatin; Histones; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lysine; Methylation; Mice; Models, Statistical; Molecular Sequence Data; Nucleus Accumbens; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Reward; Sequence Analysis, DNA | 2011 |
The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events.
Topics: Biotinylation; Carbon-Nitrogen Ligases; Epigenesis, Genetic; Gene Expression; Genome; Genomic Instability; Histones; Holocarboxylase Synthetase Deficiency; Methylation; Phenotype | 2011 |
Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.
Topics: Cell Line, Tumor; Epigenesis, Genetic; Gene Silencing; Genes, BRCA1; Genes, Tumor Suppressor; Genomic Instability; Histone Deacetylases; Histones; Humans; Hypoxia; Methylation; Promoter Regions, Genetic | 2011 |
Colorectal cancer "methylator phenotype": fact or artifact?
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Colonic Neoplasms; Colorectal Neoplasms; CpG Islands; DNA Methylation; DNA Primers; Genomic Instability; Humans; Methylation; Microsatellite Repeats; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Sequence Analysis, DNA; Sulfites | 2005 |
Transgenerational stability of the Arabidopsis epigenome is coordinated by CG methylation.
Topics: Arabidopsis; Arabidopsis Proteins; Base Composition; Cell Nucleus; Chromatin Assembly and Disassembly; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; DNA, Plant; DNA, Ribosomal; Epigenesis, Genetic; Evolution, Molecular; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genome, Plant; Genomic Instability; Genotype; Heterochromatin; Histones; Methylation; Methyltransferases; Mutation; Nuclear Proteins; Phenotype; RNA Interference; RNA, Small Interfering; Transcription Factors; Transcription, Genetic | 2007 |
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Down-Regulation; Genomic Instability; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; RNA, Small Interfering; S Phase; Tumor Suppressor Proteins | 2007 |
Hypermethylation analysis of mismatch repair genes (hmlh1 and hmsh2) in locally advanced breast cancers in Indian women.
Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; CpG Islands; DNA Mismatch Repair; Female; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Loss of Heterozygosity; Methylation; Microsatellite Instability; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2008 |