isomethyleugenol has been researched along with Folic Acid Deficiency in 80 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (18.75) | 18.7374 |
| 1990's | 23 (28.75) | 18.2507 |
| 2000's | 19 (23.75) | 29.6817 |
| 2010's | 19 (23.75) | 24.3611 |
| 2020's | 4 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, S; Jing, J; Li, B; Liu, X; Shangguan, S; Wang, L; Wu, J; Yao, X; Zhang, T | 1 |
| Bouvier, D; Brailova, M; Minet-Quinard, R; Regnier, A; Sapin, V; Szymanowski, M | 1 |
| Awwad, HM; Geisel, J; Happ, DF; MacPherson, CW; Obeid, R; Tillmann, S; Tompkins, TA; Treccani, G; Ueland, PM; Wegener, G | 1 |
| Abuawad, A; Bozack, AK; Gamble, MV; Saxena, R | 1 |
| Kasulanati, S; Venkatesan, V | 1 |
| Bozack, AK; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN | 1 |
| Cande, WZ; Guan, Q; Hammond, MC; Iavarone, AT; Li, F; Rine, J; Sadhu, MJ; Sales-Lee, J | 1 |
| Alam, S; Gamble, MV; Graziano, JH; Hall, MN; Ilievski, V; Levy, D; Liu, X; Niedzwiecki, MM; Parvez, F; Siddique, AB; Slavkovich, V | 1 |
| Cui, S; Huang, G; Jiang, M; Li, W; Xiao, Y; Zhang, X | 1 |
| Bertolo, RF; Brunton, JA; McBreairty, LE; Randell, EW; Robinson, JL | 1 |
| Blom, HJ; Burren, KA; Copp, AJ; Greene, ND; Kok, RM; Massa, V; Savery, D; Scott, JM | 1 |
| Bunout, D; de la Maza, MP; Hirsch, S; Leiva, L; Llanos, M; Montequin, MJ; Pinardi, G; Ronco, AM | 1 |
| Miller, AL | 1 |
| Bottiglieri, T; Devlin, AM; Green, TJ; Innis, SM; Singh, R | 1 |
| Fenech, M | 2 |
| Gallicano, GI; Shookhoff, JM | 1 |
| Burren, K; Copp, AJ; De Castro, SC; Greene, ND; Leung, KY; Rozen, R; Savery, D | 1 |
| Caudill, MA; Christensen, KE; Deng, L; Rozen, R; Wang, X; Wu, Q | 1 |
| Allen, RH; Brenna, JT; Caudill, MA; Gregory, JF; Malysheva, O; Stabler, SP; Wang, W; Yan, J | 1 |
| Brosnan, JT; Brosnan, ME; Lamarre, SG; Molloy, AM; Reinke, SN; Sykes, BD | 1 |
| Bressenot, A; Bronowicki, JP; Chango, A; Forges, T; Guéant, JL; Namour, F; Pellanda, H | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Caudill, M; Jiang, X; Mikael, LG; Pancer, J; Rozen, R; Wu, Q | 1 |
| Halsted, CH; Medici, V | 1 |
| Duncan, TM; Nijhout, HF; Reed, MC | 1 |
| Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ | 1 |
| Huang, S | 1 |
| Lökk, J | 1 |
| Favier, A; Galan, P; Guilland, JC; Hercberg, S; Potier de Courcy, G | 1 |
| Albanes, D; Glynn, SA | 1 |
| Davis, SR; Gregory, JF; Mackey, AD; Townsend, JH | 1 |
| Bailey, LB; Capdevila, A; Coats, BS; Davis, SR; Ghandour, H; Gregory, JF; Quinlivan, EP; Selhub, J; Shane, B; Shelnutt, KP; Shuster, JJ; Stacpoole, PW; Wagner, C | 1 |
| Bjorklund, NK; Gordon, R | 1 |
| Toohey, JI | 1 |
| Hasegawa, H; Hashimoto, T; Ogawa, K; Shinohara, Y; Tagoku, K | 1 |
| Blom, HJ; den Heijer, M; Finnell, RH; Shaw, GM | 1 |
| Lu, SC; Martínez-Chantar, ML; Mato, JM | 1 |
| Carney, MW; Reynolds, EH; Toone, BK | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Akesson, B; Fehling, C; Jägerstad, M; Stenram, U | 1 |
| Balaghi, M; Wagner, C | 2 |
| James, SJ; Pogribny, IP; Poirier, LA | 1 |
| Christman, JK | 1 |
| Christman, JK; Cravo, ML; Fleet, JC; Kim, YI; Mason, JB; Ordovas, J; Salomon, RN; Selhub, J; Smith, D | 1 |
| Henning, SM; Jacob, RA; Pianalto, FS; Swendseid, ME; Zhang, JZ | 1 |
| Basnakian, AG; James, SJ; Lopatina, NG; Miller, BJ; Pogribny, IP; Poirier, LA | 1 |
| Rogers, AE | 1 |
| Kennedy, DG; Kennedy, S; Molloy, AM; Scott, JM; Weir, DG | 1 |
| Poirier, LA | 1 |
| Miller, JW; Nadeau, MR; Selhub, J; Smith, D; Smith, J | 1 |
| Rees, MM; Rodgers, GM | 1 |
| Barkhof, F; Braam, M; Frequin, ST; Hommes, OR; Wevers, RA | 1 |
| Dolnick, BJ; Hsueh, CT | 1 |
| Christensen, B | 1 |
| Bottiglieri, T | 1 |
| Bottiglieri, T; Lowenthal, D; Parnetti, L | 1 |
| Aubard, Y; Baudet, JH; Chinchilla, AM; Piver, P | 1 |
| Cattaneo, M; Lecchi, A; Lombardi, R; Zighetti, ML | 1 |
| Allman-Farinelli, MA; Jacob, RA; Jenden, DJ; Swendseid, ME | 1 |
| Scott, JM; Weir, DG | 1 |
| Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK | 1 |
| Gustafson, L; Hultberg, B; Isaksson, A; Nilsson, K | 1 |
| Mathé, G | 1 |
| Baumgartner, TG; Cuskelly, GJ; Gregory, JF; Stacpoole, PW; Williamson, J | 1 |
| Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
| Campbell, C; Hillman, RS; McGuffin, R | 1 |
| Buehring, YS; Poirier, LA; Stokstad, EL | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Henning, SM; McKee, RW; Swendseid, ME | 1 |
| Dizik, M; Hoshina, S; Hsieh, LL; Wainfan, E; Weinstein, IB | 1 |
| Christman, JK; Dizik, M; Stender, M; Wainfan, E | 1 |
| Dizik, M; Kilkenny, M; Wainfan, E | 1 |
| Shane, B; Stokstad, EL | 1 |
| Balis, ME; Dizik, M; Hluboky, M; Wainfan, E | 1 |
| Billings, RE; Hansen, DK | 1 |
| Valencia, R | 1 |
| Barness, LA; Morrow, G | 1 |
28 review(s) available for isomethyleugenol and Folic Acid Deficiency
| Article | Year |
|---|---|
Nutrition, one-carbon metabolism and arsenic methylation.
Topics: Animals; Arsenic; Carbon; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Food; Humans; Methylation; Nutritional Status; Observational Studies as Topic; Pregnancy; Prenatal Exposure Delayed Effects | 2021 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression.
Topics: Antioxidants; Biopterins; Depression; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Neurotransmitter Agents; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Tetrahydrofolates | 2008 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
A new perspective on neural tube defects: folic acid and microRNA misexpression.
Topics: Animals; DNA Methylation; Folic Acid Deficiency; Histones; Humans; Methylation; MicroRNAs; Models, Biological; Neural Tube; Neural Tube Defects | 2010 |
Folate, alcohol, and liver disease.
Topics: Absorption; Alcohol Drinking; Animals; Antioxidants; Disease Models, Animal; Epigenesis, Genetic; Ethanol; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Intestine, Small; Liver; Liver Diseases, Alcoholic; Methionine; Methylation | 2013 |
Histone methyltransferases, diet nutrients and tumour suppressors.
Topics: Amino Acid Sequence; Diet; Folic Acid Deficiency; Forecasting; Genes, Tumor Suppressor; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Methionine; Methylation; Methyltransferases; Molecular Sequence Data; Neoplasms; Protein Methyltransferases; Sequence Homology, Amino Acid | 2002 |
News and views on folate and elderly persons.
Topics: Aged; Cardiovascular Diseases; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Mental Disorders; Methylation; Neoplasms; Risk Factors; Vitamin B 12 Deficiency | 2003 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data].
Topics: Animals; Arteriosclerosis; Biomarkers; Cystathionine beta-Synthase; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Homocystinuria; Humans; Hyperhomocysteinemia; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Models, Biological; Nitric Oxide; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Rats; Risk Factors; S-Adenosylmethionine; Signal Transduction; Thrombophilia; Vascular Diseases; Vasodilation; Vitamin B 6 Deficiency | 2003 |
Folate and cancer: a review of the literature.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neoplasms; Risk Factors | 1994 |
A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations of the cytoskeleton.
Topics: Animals; Cytoskeletal Proteins; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neural Tube Defects; Protein Processing, Post-Translational | 2006 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood?
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Biological Transport; Bone Marrow; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methionine; Methylation; Myelin Sheath; Nerve Tissue; S-Adenosylmethionine; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death.
Topics: Animals; Cell Death; Chromosomal Instability; Cytokinesis; Folic Acid Deficiency; Gene Silencing; Heterochromatin; Humans; Methylation; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitosis; Models, Biological | 2006 |
Neural tube defects and folate: case far from closed.
Topics: Animals; Central Nervous System; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Neural Tube Defects | 2006 |
Methionine metabolism and liver disease.
Topics: Animals; Choline; Choline Deficiency; Folic Acid Deficiency; Humans; Liver Diseases; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation | 2008 |
Lipotrope deficiency and persistent changes in DNA methylation. Lipotrope deficiency and DNA methylation.
Topics: Animals; Choline Deficiency; DNA; Folic Acid Deficiency; Humans; Lipid Metabolism; Liver; Methionine; Methylation; Neoplasms; Vitamin B 12 Deficiency | 1995 |
Methyl donors in the diet and responses to chemical carcinogens.
Topics: Animals; Carcinogens; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms, Experimental; Methionine; Methylation; Neoplasms | 1995 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
Folate, alcohol, methionine, and colon cancer risk: is there a unifying theme?
Topics: Alcohol Drinking; Animals; Colonic Neoplasms; DNA; Ethanol; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Risk Factors; S-Adenosylmethionine | 1994 |
Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Blood Coagulation Factors; Blood Platelets; Child; Cystathionine beta-Synthase; Endothelium, Vascular; Fibrinolytic Agents; Folic Acid Deficiency; Homocysteine; Humans; Incidence; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Penicillamine; Risk Factors; Thrombosis; Vascular Diseases; Vitamin B 12; Vitamin B 6 Deficiency; Vitamins | 1993 |
[Folate deficiency, cancer and congenital abnormalities. Is there a connection?].
Topics: Adult; Congenital Abnormalities; DNA; Female; Folic Acid; Folic Acid Deficiency; Hematinics; Humans; Methylation; Neoplasms; Pregnancy | 1996 |
Folate, vitamin B12, and neuropsychiatric disorders.
Topics: Depressive Disorder; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Methylation; Multiple Sclerosis; Vitamin B 12; Vitamin B 12 Deficiency | 1996 |
Role of homocysteine in age-related vascular and non-vascular diseases.
Topics: Aged; Aging; Alcoholism; Central Nervous System; Cerebrovascular Disorders; Cognition; Coronary Disease; Depression; Estrogens; Female; Folic Acid Deficiency; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Peripheral Vascular Diseases; Renal Replacement Therapy; Vascular Diseases; Vitamin B 12 Deficiency | 1997 |
[Folates and the neural tube. Review of the literature].
Topics: Animals; Europe; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Homocysteine; Humans; Methionine; Methylation; Neural Crest; Neural Tube Defects; Preconception Care; Pregnancy; Prenatal Care; Prevalence; Risk Factors | 1997 |
Brain function in the elderly: role of vitamin B12 and folate.
Topics: Aged; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Nervous System Diseases; S-Adenosylmethionine; Vitamin B 12; Vitamin B 12 Deficiency | 1999 |
Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly.
Topics: Aged; Biomarkers; Folic Acid Deficiency; Geriatric Assessment; Homocysteine; Humans; Mental Disorders; Methylation; Neuropsychological Tests; Severity of Illness Index; Vitamin B 12 Deficiency | 2001 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Vitamin B12-folate interrelationships.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
[Control of cellular division by vitamin B 12 and folates].
Topics: Anemia, Macrocytic; Anemia, Pernicious; Animals; Cell Division; Euglena gracilis; Folic Acid; Folic Acid Deficiency; Humans; Leukemia; Methylation; Nucleic Acids; Nucleotides; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
6 trial(s) available for isomethyleugenol and Folic Acid Deficiency
| Article | Year |
|---|---|
Folic acid supplementation enhances arsenic methylation: results from a folic acid and creatine supplementation randomized controlled trial in Bangladesh.
Topics: Adult; Arsenic; Arsenicals; Bangladesh; Creatine; Cross-Sectional Studies; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Humans; Inactivation, Metabolic; Male; Mercury Poisoning; Methylation; Middle Aged; Nutrition Therapy; Vitamin B Complex; Water Pollutants, Chemical; Young Adult | 2019 |
MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline.
Topics: Adolescent; Adult; Betaine; Choline; Deuterium; Dietary Supplements; Folic Acid Deficiency; Genotype; Humans; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mexican Americans; Middle Aged; Phosphatidylcholines; Sarcosine; Staining and Labeling; Young Adult | 2011 |
In vivo methylation capacity is not impaired in healthy men during short-term dietary folate and methyl group restriction.
Topics: Administration, Oral; Adult; Carnitine; Choline; Choline Deficiency; Creatinine; Cross-Over Studies; Diet; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans; Male; Methionine; Methylation; Middle Aged; Niacinamide; Time Factors | 1995 |
Folate nutriture alters choline status of women and men fed low choline diets.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Choline; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipids; Male; Methionine; Methylation; Middle Aged; Nutritional Physiological Phenomena; Nutritional Status; Phosphatidylcholines; Reference Values; S-Adenosylmethionine | 1999 |
Homocysteine, folate, methylation, and monoamine metabolism in depression.
Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methylation; Middle Aged; S-Adenosylmethionine; Vitamin B 12 | 2000 |
Deficiencies of folate and vitamin B(6) exert distinct effects on homocysteine, serine, and methionine kinetics.
Topics: Adult; Amino Acids; Diet; Folic Acid Deficiency; Homocysteine; Humans; Leucine; Male; Methionine; Methylation; Nutritional Physiological Phenomena; Nutritional Status; Polymorphism, Genetic; Serine; Vitamin B 6 Deficiency | 2001 |
46 other study(ies) available for isomethyleugenol and Folic Acid Deficiency
| Article | Year |
|---|---|
The effect of folic acid deficiency on Mest/Peg1 in neural tube defects.
Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Female; Fetus; Folic Acid Deficiency; Gene Expression Regulation; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Methylation; Mice; Mice, Inbred C57BL; Neural Tube Defects; Proteins; Wnt Signaling Pathway | 2021 |
[Remethylation disorders: about two cases].
Topics: Alcoholism; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Humans; Infant, Newborn; Metabolic Networks and Pathways; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Muscle Spasticity; Psychotic Disorders; Vitamin B 12 | 2020 |
The Kynurenine Pathway Is Upregulated by Methyl-deficient Diet and Changes Are Averted by Probiotics.
Topics: Animals; Choline; Choline Deficiency; Folic Acid Deficiency; Kynurenine; Male; Methionine; Methylation; Probiotics; Rats; Rats, Sprague-Dawley; Tryptophan | 2021 |
Understanding pluripotency under folic acid deficiency using embryonic stem cells as an in vitro model.
Topics: DNA; DNA Methylation; Embryonic Development; Embryonic Stem Cells; Epigenesis, Genetic; Female; Folic Acid; Folic Acid Deficiency; Histones; Humans; In Vitro Techniques; Methylation; Micronutrients; Models, Theoretical; Pregnancy; Teratoma | 2018 |
Nutritional control of epigenetic processes in yeast and human cells.
Topics: Epigenesis, Genetic; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Histones; Humans; Infant, Newborn; K562 Cells; Methionine; Methylation; Neural Tube Defects; Pregnancy; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Species Specificity | 2013 |
Interaction of plasma glutathione redox and folate deficiency on arsenic methylation capacity in Bangladeshi adults.
Topics: Adult; Aged; Arsenic; Arsenicals; Bangladesh; Cacodylic Acid; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Female; Folic Acid; Folic Acid Deficiency; Glutathione; Glutathione Disulfide; Humans; Male; Methylation; Methyltransferases; Middle Aged; Oxidation-Reduction; S-Adenosylmethionine | 2014 |
Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells.
Topics: Alzheimer Disease; Cell Line, Tumor; Cell Survival; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neuroblastoma; Okadaic Acid; Phosphorylation; Protein Phosphatase 2; tau Proteins | 2015 |
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Protein Biosynthesis; Protein Processing, Post-Translational; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Tritium | 2016 |
Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.
Topics: Animals; Disease Susceptibility; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Methylation; Mice; Mice, Transgenic; Mutation; Neural Tube Defects; Paired Box Transcription Factors; PAX3 Transcription Factor | 2008 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atherosclerosis; Endothelium, Vascular; Folic Acid Deficiency; Homocysteine; In Vitro Techniques; Liver; Male; Methylation; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; S-Adenosylmethionine; Vasodilation; Vitamin B 12; Vitamin B 12 Deficiency | 2008 |
Hepatic acyl-coenzyme a:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia.
Topics: Acyl Coenzyme A; Animals; Cholesterol Esters; CpG Islands; Cystathionine beta-Synthase; Diet; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Lipid Metabolism; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oleic Acid; RNA, Messenger; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2 | 2010 |
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation.
Topics: Animals; Carbon; DNA-Binding Proteins; Female; Fibroblasts; Folic Acid; Folic Acid Deficiency; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Mutant Strains; Neural Tube Defects; Pregnancy; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine Monophosphate; Transcription Factors | 2010 |
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carbon; Choline; Diet; Fatty Liver; Female; Ferredoxin-NADP Reductase; Folic Acid; Folic Acid Deficiency; Gene Expression; Homocysteine; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; RNA, Messenger; Sex Factors | 2010 |
Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration.
Topics: Animals; Biomarkers; Brain; Folic Acid Deficiency; Formates; Homocysteine; Hyperhomocysteinemia; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methionine; Methylation; Methylmalonic Acid; Models, Biological; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2012 |
Fumonisin FB1 treatment acts synergistically with methyl donor deficiency during rat pregnancy to produce alterations of H3- and H4-histone methylation patterns in fetuses.
Topics: Abnormalities, Drug-Induced; Animals; Choline Deficiency; Fatty Liver; Female; Folic Acid; Folic Acid Deficiency; Folic Acid Transporters; Fumonisins; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Liver; Maternal Nutritional Physiological Phenomena; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Teratogens; Vitamin B 12 Deficiency | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Homocystinuria; Interferon-gamma; Liver; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Transgenic; Muscle Spasticity; Placenta; Pregnancy; Pregnancy Complications; Psychotic Disorders; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen | 2013 |
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
Topics: Cystathionine beta-Synthase; Down Syndrome; Folic Acid; Folic Acid Deficiency; Half-Life; Homocysteine; Humans; Methionine; Methylation; Models, Theoretical; Nutrition Surveys; Nutritional Status; Oxidative Stress; S-Adenosylmethionine; Vitamin B 12 Deficiency; Vitamin B Complex; Vitamins | 2013 |
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation | 2013 |
Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation.
Topics: Amino Acids; Caco-2 Cells; Culture Media; Epithelial Cells; Folic Acid Deficiency; Homocysteine; Humans; Intestinal Mucosa; Intestines; Kinetics; Methionine; Methylation; Serine | 2004 |
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Topics: Adult; Amino Acids; Female; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Leucine; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Serine | 2005 |
Distinct effects of folate and choline deficiency on plasma kinetics of methionine and homocysteine in rats.
Topics: Animals; Choline Deficiency; Folic Acid Deficiency; Homocysteine; Kinetics; Male; Methionine; Methylation; Rats; Rats, Sprague-Dawley | 2006 |
Methylation and mood.
Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency | 1984 |
Tissue levels of S-adenosylmethionine and S-adenosylhomocysteine in rats fed methyl-deficient, amino acid-defined diets for one to five weeks.
Topics: Animals; Body Weight; Choline Deficiency; Diet; Folic Acid Deficiency; Homocysteine; Kinetics; Liver; Lung; Male; Methionine; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine; Testis; Tissue Distribution; Vitamin B 12 Deficiency | 1983 |
Effect of experimental folate deficiency on lipid metabolism in liver and brain.
Topics: Animals; Brain; Fatty Acids; Folic Acid Deficiency; Lipid Metabolism; Liver; Male; Methylation; Phospholipids; Rats; Rats, Inbred Strains | 1982 |
Folate deficiency inhibits pancreatic amylase secretion in rats.
Topics: Aging; Amino Acids; Amylases; Animals; Body Weight; Cholecystokinin; Folic Acid Deficiency; Male; Methylation; Pancreas; Rats; Rats, Sprague-Dawley | 1995 |
Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats.
Topics: Animals; Base Sequence; Cytosine; Folic Acid Deficiency; Genes, p53; Liver; Male; Methylation; Molecular Sequence Data; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1995 |
Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats.
Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation, Neoplastic; Genes, myc; Liver; Male; Methionine; Methylation; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1995 |
Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats.
Topics: Animals; Cell Nucleus; Chromatin; DNA; DNA Damage; Endodeoxyribonucleases; Evaluation Studies as Topic; Exons; Folic Acid Deficiency; Genes, p53; Genome; Kinetics; Liver; Male; Methylation; Oxidants; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Sensitivity and Specificity; Up-Regulation | 1995 |
Effects of the disruption of transmethylation in the central nervous system: an animal model.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Cystathionine; Depressive Disorder; Folic Acid Deficiency; Liver; Methylation; Methyltransferases; Plasma; S-Adenosylmethionine; Spinal Cord; Swine; Vitamin B Deficiency | 1994 |
Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism.
Topics: Animals; Ethionine; Folic Acid Deficiency; Homocysteine; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1994 |
DNA methylation in folate deficiency: use of CpG methylase.
Topics: Animals; DNA; DNA-Cytosine Methylases; Escherichia coli; Folic Acid Deficiency; Kinetics; Liver; Male; Methylation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reference Values; Spiroplasma | 1993 |
Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.
Topics: Adult; Female; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intravenous; Male; Methylation; Methylprednisolone Hemisuccinate; Middle Aged; Multiple Sclerosis; Myelin Sheath; Vitamin B 12; Vitamin B 12 Deficiency | 1993 |
Altered folate-binding protein mRNA stability in KB cells grown in folate-deficient medium.
Topics: Carrier Proteins; Cell Line; Culture Media; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Deficiency; Gene Expression Regulation; Humans; Methylation; Receptors, Cell Surface; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Is the oral methionine loading test insensitive to the remethylation pathway of homocysteine?
Topics: Artifacts; Folic Acid Deficiency; Genetic Predisposition to Disease; Genotype; Homocysteine; Humans; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Reproducibility of Results; Risk Factors; Thrombophilia | 1999 |
A dysmethylation syndrome, bound to folates and/or vitamin B12 and/or methionine abnormalities? Diagnosis, prevention and treatment considerations.
Topics: DNA Methylation; Folic Acid Deficiency; Hematologic Diseases; Humans; Hyperhomocysteinemia; Iatrogenic Disease; Methionine; Methylation; Neoplasms; Nervous System Diseases; Selenium; Vascular Diseases; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 2001 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
Alcohol interference with the folate enterohepatic cycle.
Topics: Alcoholism; Animals; Bile; Disease Models, Animal; Enterohepatic Circulation; Female; Folic Acid; Folic Acid Deficiency; Humans; Liver; Methylation; Oxidation-Reduction; Rats | 1977 |
Folate deficiency in the livers of diethylnitrosaminetreated rats.
Topics: Animals; Diethylnitrosamine; Folic Acid Deficiency; Glutamates; In Vitro Techniques; Liver; Male; Methionine; Methylation; Nitrosamines; Rats; S-Adenosylmethionine; Tetrahydrofolates | 1976 |
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutathione; Homocysteine; Lipids; Liver; Male; Methionine; Methylation; Niacinamide; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Altered expression of retrovirus-like sequences and cellular oncogenes in mice fed methyl-deficient diets.
Topics: Animals; Cell Division; Choline Deficiency; DNA Replication; Folic Acid Deficiency; Genes, ras; Kinetics; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Proto-Oncogenes; Reference Values; Retroviridae; Transcription, Genetic; Vitamin B 12 Deficiency | 1989 |
Rapid appearance of hypomethylated DNA in livers of rats fed cancer-promoting, methyl-deficient diets.
Topics: Animals; Choline Deficiency; DNA; Folic Acid Deficiency; Liver; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; RNA, Transfer; Vitamin B 12 Deficiency | 1989 |
Comparison of methyltransferase activities of pair-fed rats given adequate or methyl-deficient diets.
Topics: Animals; Choline Deficiency; Folic Acid Deficiency; Male; Methionine; Methylation; Protein Methyltransferases; Rats; Rats, Inbred F344; tRNA Methyltransferases; Vitamin B 12 Deficiency | 1988 |
Altered tRNA methylation in rats and mice fed lipotrope-deficient diets.
Topics: Animals; Choline Deficiency; Folic Acid Deficiency; Liver; Male; Methionine; Methylation; Mice; Rats; RNA, Transfer; tRNA Methyltransferases; Vitamin B 12 Deficiency | 1986 |
Effects of nitrous oxide on maternal and embryonic folate metabolism in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Body Weight; Chromatography, High Pressure Liquid; Embryo, Mammalian; Female; Fetal Resorption; Folic Acid; Folic Acid Deficiency; Liver; Male; Methylation; Nitrous Oxide; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Combined vitamin responsiveness in homocystinuria.
Topics: Adolescent; Adult; Amino Acids; Child; Drug Synergism; Female; Folic Acid; Folic Acid Deficiency; Glycine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Male; Metabolic Diseases; Methionine; Methylation; Pyridoxine; Vitamin B 12 | 1972 |