isomethyleugenol has been researched along with Experimental Neoplasms in 203 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 174 (85.71) | 18.7374 |
| 1990's | 11 (5.42) | 18.2507 |
| 2000's | 4 (1.97) | 29.6817 |
| 2010's | 11 (5.42) | 24.3611 |
| 2020's | 3 (1.48) | 2.80 |
| Authors | Studies |
|---|---|
| Baldan, S; Gellerman, G; Patsenker, L; Prasad, C; Sherman, MY; Thankarajan, E; Tuchinsky, H; Walunj, D | 1 |
| Hao, H; Li, W; Lu, S; Qin, N; Wang, Y; Xiang, H; Yuan, J; Zhao, C | 1 |
| Hsieh, MC; Huang, CY; Huang, WS; Kuo, HC; Lee, KC; Lee, KF; Sheen, JM; Shen, CH; Teng, CC; Tung, SY | 1 |
| Doi, H; Hashizume, Y; Onoe, H; Ozaki, D; Shibata, N; Suzuki, M; Tahara, T; Takatani, S; Tsuji, M; Watanabe, Y | 1 |
| Durban, VM; Phesse, TJ; Sansom, OJ | 1 |
| Alves, G; Arnaud, P; Baron, S; Caira, F; De Boussac, H; Dufour, J; Lobaccaro, JM; Pommier, AJ; Trousson, A; Val, P; Viennois, E; Volle, DH | 1 |
| Lu, L; Ma, H; Qian, J; Wu, J | 1 |
| Collins, L; Crowley, J; Elhammali, A; Ippolito, JE; Marasa, J; Piwnica-Worms, D | 1 |
| Bodine, DM; Crawford, NP; Dworkin, AM; Gildea, D; Lee, M; Lichtenberg, J; Patel, SJ; Trivedi, NS | 1 |
| Armstrong, SA; Banka, D; Bernt, KM; Bradner, JE; Chang, J; Chen, CW; Chen, L; Cihan, A; Deshpande, A; Deshpande, AJ; Dias, S; Dzhekieva, L; Fazio, M; Ibáñez, G; Koche, R; Krivtsov, A; Luo, M; Roeder, RG; Sinha, AU; Zhu, N | 1 |
| Geng, P; Huang, B; Li, Y; Li, Z; Lin, C; Liu, DX; Liu, X; Liu, Y; Lu, J; Tan, J; Wang, G; Yan, X; Zhang, N; Zhang, Y | 1 |
| Bykov, VJ; Lambert, JM; Wiman, KG; Zache, N | 1 |
| Chan, D; Fernandez, S; Giaccia, AJ; Krieg, AJ; Rankin, EB; Razorenova, O | 1 |
| Bieblová, J; Bubeník, J; Indrová, M; Mikyšková, R; Polláková, V; Reiniš, M; Símová, J; Stěpánek, I | 1 |
| Casero, RA; Hanigan, CL; Jin, L; Park, BH; Wang, W; Woster, PM; Wu, Y | 1 |
| Zhu, BT | 1 |
| Buettner, R; Corzilius, L; Doerfler, W; Dorn, A; Hilger-Eversheim, K; Hohlweg, U; Hösel, M; Niemann, A; Remus, R; Schmitz, B; Schramme, A; Webb, D | 1 |
| Anisowicz, A; Gadi, IK; Harrison, JJ; Raffeld, M; Sager, R | 1 |
| Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Forchhammer, J; Olsson, L | 1 |
| Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C | 1 |
| Hoshino, J; Kröger, H; Seifert, R | 1 |
| Doerfler, W | 2 |
| Stevens, JG; Wettstein, FO | 1 |
| Shay, JW | 1 |
| Andjelkovich, DA; Beauchamp, RO; Boreiko, CJ; Bus, JS; Popp, JA | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Bourgeois, S; Gasson, JC; Ryden, T | 1 |
| Doerfler, W; Kuhlmann, I | 1 |
| Brown, A; Huang, RC; Mays-Hoopes, LL | 1 |
| Day, RS; Yagi, T; Yarosh, DB | 1 |
| Eremenko, T; Volpe, P | 1 |
| Bursics, L; Gyapay, G; Jeney, A; Lapis, K; Szende, B; Tyihák, E | 1 |
| Monard, D; Murato, K | 1 |
| Asbery, LJ; Chandler, PM; Harris, G; Jones, MG; Lawley, PD | 1 |
| Alekandrov, VA; Anisimov, VN; Bespalov, VG; Korsakov, MV; Likhachev, AJ; Napalkov, NP; Ovsyannikov, AI; Popovich, IG; Tomatis, L | 1 |
| Lijinsky, W; Reuber, MD | 2 |
| Glazer, RI; Lloyd, LS | 1 |
| Boehm, TL; Drahovsky, D | 1 |
| Okada, M; Suzuki, E | 1 |
| Montesano, R | 1 |
| Daub, GH; Iyer, RP; Lyga, JW; Secrist, JA; Slaga, TJ | 1 |
| Bynum, JW | 1 |
| Akamatsu, Y; Maeda, M; Tanaka, Y | 1 |
| Tisdale, MJ | 1 |
| MacLeod, AR; Szyf, M | 1 |
| Costa, M | 1 |
| Counts, JL; Goodman, JI | 1 |
| Della Porta, G; Dragani, TA; Farza, H; Manenti, G; Metzler, T; Pourcel, C; Tiollais, P | 1 |
| DeBaun, MR; Feinberg, AP; Rainier, S | 1 |
| Bohuon, C; Pallardy, M; Saas, P | 1 |
| Ganther, HE | 1 |
| Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P | 1 |
| Mennel, HD; Zülch, KJ | 1 |
| Habs, M; Schmähl, D; Wiessler, M | 1 |
| Hurlbert, RB; Liau, MC | 2 |
| Hochberg, AA; Morris, HP; Stratman, FW; Zahlten, RN | 1 |
| Hilliard, JK; Sneider, TW | 1 |
| Desrosiers, RC; Friderici, KH; Rottman, FM | 1 |
| Kerr, SJ | 2 |
| Busch, H; Nazar, RN; Sitz, TO | 1 |
| Friderici, K; Kaehler, M; Rottman, F | 1 |
| Lapis, K; Szende, B; Tyihák, E | 1 |
| Hurlbert, RB; Knight, CA; Liau, MC; Lin, GW | 1 |
| Borek, E; Kuchino, Y | 1 |
| Berry, DL; Bracken, WM; Fischer, SM; Miller, DR; Slaga, TJ; Viaje, A | 1 |
| Heller-Schöch, G; Schöch, G | 1 |
| Lijinsky, W; Taylor, HW | 2 |
| Bayev, AA; Gambaryan, AS; Morozov, IA; Venkstern, TV | 1 |
| Horie, M; Mori, Y; Toyoshi, K | 1 |
| Hammesfahr, P; Ravikumar, PR; Sih, CJ | 1 |
| Buecheler, J; Cooper, HK; Diessner, H; Kleihues, P; Kolar, GF | 1 |
| Doerjer, G; Hodgson, RM; Keefer, LK; Kleihues, P; Rice, JM; Roller, PP | 1 |
| Auer, B; Fabricant, JD; Schweiger, M; Wagner, EF | 1 |
| Amin, S; Hecht, SS; Hoffmann, D; Rivenson, A | 1 |
| Luthardt, FW; Riggs, AD; Roberts-Ems, J; Singer, J | 1 |
| Buecheler, J; Cooper, HK; Kleihues, P | 1 |
| Bursics, L; Jeney, A; Kopper, L; Lapis, K; Szarvas, T; Szende, B; Tyihák, E; Ujhelyi, E | 1 |
| Asberry, BE; Coleman, RE; Fair, WR; Primeau, JL; Straatmann, MG; Ter-Pogossian, MM; Welch, MJ | 1 |
| Green, U; Kaufman, DG; Magee, PN; Mohr, U; Reznik, G; Swann, PF | 1 |
| Erickson, J; Kupper, R; Nagel, D; Toth, B | 1 |
| Jones, PA; Rideout, WM; Shen, JC; Spruck, CH; Tsai, YC | 1 |
| Baker, N; Blank, EW; Ceriani, RL; Lin, C | 1 |
| Christman, JK; Dizik, M; Wainfan, E | 1 |
| Alvarez, E; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Jones, PA; Kautiainen, TL | 1 |
| Frost, P; Kerbel, RS; Liteplo, R | 1 |
| Newberne, PM; Rogers, AE | 1 |
| Matthews, AM; Shay, JW; Walker, C | 1 |
| Nahon, JL | 1 |
| Babiss, LE; Fisher, PB; Zimmer, SG | 1 |
| Christman, JK; Dizik, M; Stender, M; Wainfan, E | 1 |
| Billings, PC; Kennedy, AR; Weichselbaum, RR | 1 |
| Doerfler, W; Lichtenberg, U; Zock, C | 1 |
| Chriqui-Zeira, E; Kedar, E; Mann, V; Razin, A; Szyf, M | 1 |
| Amin, SG; Chung, FL; Hecht, SS; Morse, MA; Wang, CX | 1 |
| Kovatch, RM; Lijinsky, W | 1 |
| Adams, RL; Ball, K; Bryans, M; McGarvey, M; Rinaldi, A | 1 |
| Fioretti, MC; Puccetti, P; Romani, L | 1 |
| Frost, P; Kendal, WS | 1 |
| Ip, C | 1 |
| Kovatch, RM; Lijinsky, W; Saavedra, JE | 1 |
| Kobayashi, H | 1 |
| Dennis, JW; Kiyohara, T; Roder, JC | 1 |
| Anisimov, VN; Likhachev, AIa; Ovsiannikov, AI | 2 |
| Carver, JP; Dell, A; Dennis, JW; Fukuda, M; Laferté, S | 1 |
| Likhachev, AJ | 1 |
| Khodosova, IA | 1 |
| Coleman, DT; Geddie, NG; Hoffmann, D; La Voie, EJ; Rice, JE | 1 |
| Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N | 1 |
| Castonguay, A; Foiles, PG; Hecht, SS; Trushin, N | 1 |
| Brière, N | 1 |
| Adamson, RH; Gallo, RC; O'Gara, RW; Waalkes, TP | 2 |
| Kroes, R; Weisburger, JH; Williams, GM | 1 |
| Baglei, EA; Iurkovskaia, TN; Sidorik, EP | 1 |
| Fahmy, MJ; Fahmy, OG | 1 |
| Sakai, K; Yamane, Y | 1 |
| Krüger, FW; Osswald, H; Schelten, E; Walker, G | 1 |
| Lichtenstein, AV; Piker, EG; Shapot, VS | 1 |
| Bar-Meir, S; Fridlender, B; Kaye, AM; Salomon, R | 1 |
| Behki, RM; Geil, JH; Morgan, WS; Stenger, RJ | 1 |
| Busch, H; Nakamura, T; Prestayko, AW | 1 |
| Dickie, MM; Hancock, RL | 1 |
| Bilik, E; Sheid, B | 1 |
| Potter, VR; Sneider, TW | 1 |
| Chang, LO; Looney, WB; Morris, HP | 1 |
| Hall, RH | 1 |
| Busch, H; Hodnett, JL; Moriyama, Y; Prestayko, AW | 1 |
| Hancock, RL; Turner, G | 1 |
| Flatt, NC; Hurlbert, RB; Liau, MC | 1 |
| Hakomori, S; Siddiqui, B | 1 |
| Borek, E; Kerr, SJ; Sharma, OK | 1 |
| Sneider, TW | 1 |
| Byvoet, P | 2 |
| Lee, HW; Morris, HP; Paik, WK | 1 |
| Shearer, RW; Smuckler, EA | 1 |
| Glover, EL; Reuber, MD; Stromberg, K | 1 |
| Sneider, T | 1 |
| Dixon, B; Fiala, AE; Fiala, S | 1 |
| Craft, K; Glick, M; Orlando, RA; Wissler, RW | 1 |
| Hayashi, Y | 1 |
| Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ | 1 |
| Hunt, JB; Hurlbert, RB; Liau, MC; Smith, DW | 1 |
| Borchert, P; Miller, EC; Miller, JA; Shires, TK | 1 |
| Bayev, AA; Shershneva, LP; Venkstern, TV | 2 |
| Pitot, HC; Wilkinson, DS | 1 |
| McFarlane, ES | 1 |
| Sharma, OK | 1 |
| Chia, LL; Morris, HP; Randerath, E; Randerath, K | 2 |
| Nau, F | 1 |
| Abakumova, OIu; Gorbacheva, LB; Kukushkina, GV; Kutsenko, NG; Lerman, MI | 1 |
| Den Engelse, L | 1 |
| Howard, E; Tidwell, T | 1 |
| Desrosiers, R; Friderici, K; Rottman, F | 1 |
| Inose, M; Iwanami, Y | 1 |
| Goth, R; Rajewsky, MF | 1 |
| Kleihues, P; Margison, GP | 1 |
| Kapustin, IuM; Likhachev, AIa; Pozharisskiĭ, KM; Shaposhnikov, IaD | 1 |
| Shier, WT | 1 |
| Fedorov, NA | 1 |
| Brown, EV; Kruegel, A | 1 |
| Goodman, JI; Potter, VR | 1 |
| de Lauzon, S; Hurst, L; Jayle, MF; Lacassagne, A | 1 |
| Rottman, FM; Stuart, SE | 1 |
| Hadjiolov, D; Mundt, D | 1 |
| Nemoto, N; Takayama, S | 1 |
| Boutwell, RK; Bowden, GT | 1 |
| McFarlane, ES; Shaw, GJ | 1 |
| Datta, B; Datta, RK | 1 |
| Blair, DG; Dell'Orco, RT; Morgan, JF | 1 |
| Wagner, GN | 1 |
| Lombardini, JB; Talalay, P | 1 |
| Brown, EV; Snider, BJ | 1 |
| Hacker, B; Maag, TA; Mandel, LR | 1 |
| Gotoh, S; Higashi, K; Nishinaga, K; Sakamoto, Y | 1 |
| Kopper, L; Lapis K Tyihák, E; Szende, B | 1 |
| Hiraki, S | 1 |
| Hawks, A; Pegg, AE | 1 |
| Duguid, C; Harvey, RG; Huisman, H; Pataki, J; Rabideau, PW | 1 |
| McLean, AE; Swann, PF | 1 |
| Riddle, M; Turkington, RW | 1 |
| Evans, VJ; Gantt, R; Quinn, CE | 1 |
| Bentvelzen, PA; den Engelse, L; Emmelot, P | 1 |
| Allan, PW; Bennett, LL | 1 |
| Burdon, RH | 1 |
| Frei, JV | 1 |
| Gantt, RR | 1 |
| Foley, WA; Galitski, SB; Gutmann, HR | 1 |
| Fox, M | 1 |
| Kahle, P; Kessel, H; Kröger, H | 1 |
| Brookes, P; Dipple, A; Lawley, PD | 1 |
| Dahmus, ME; McConnell, DJ | 1 |
22 review(s) available for isomethyleugenol and Experimental Neoplasms
| Article | Year |
|---|---|
Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models.
Topics: Animals; Apoptosis; CRISPR-Cas Systems; Disease Models, Animal; Epithelium; Genes, Tumor Suppressor; Humans; Intestinal Neoplasms; Methylation; Mice; Mice, Transgenic; Neoplasms, Experimental; Neoplastic Stem Cells; Oncogenes; Signal Transduction; Stem Cells | 2017 |
Uptake, fixation, and expression of foreign DNA in mammalian cells: the organization of integrated adenovirus DNA sequences.
Topics: Adenoviridae; Animals; Attachment Sites, Microbiological; Base Sequence; Brain Neoplasms; Cell Line; Cell Transformation, Viral; Cricetinae; DNA Restriction Enzymes; DNA, Viral; Gene Amplification; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms, Experimental; Operon; Protein Biosynthesis; Rats; Recombination, Genetic; Tumor Virus Infections; Virus Replication | 1982 |
Cytoplasmic modification of nuclear gene expression.
Topics: Animals; Cell Differentiation; Cell Nucleus; Cytoplasm; DNA; Gene Expression Regulation; Humans; Hybrid Cells; Methylation; Mice; Neoplasms, Experimental; Rats | 1983 |
A critical review of the literature on hydrogen sulfide toxicity.
Topics: Abnormalities, Drug-Induced; Animals; Carotid Body; Eye; Female; Fishes; Humans; Hydrogen Sulfide; Male; Metalloproteins; Methemoglobin; Methylation; Mutagens; Neoplasms, Experimental; Nervous System; Odorants; Oxidation-Reduction; Oxygen; Plants; Pregnancy; Proteins; Reproduction; Respiratory System; Sulfates | 1984 |
Uptake of foreign DNA by mammalian cells via the gastrointestinal tract in mice: methylation of foreign DNA--a cellular defense mechanism.
Topics: Adenoviruses, Human; Administration, Oral; Animals; Bacteriophage M13; Base Sequence; Cell Line, Transformed; Cricetinae; Digestive System; DNA; DNA, Viral; Feces; Humans; Intestinal Absorption; Leukocytes; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Insertional; Neoplasms, Experimental; Oligodeoxyribonucleotides; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured | 1995 |
Model for the epigenetic mechanism of action of nongenotoxic carcinogens.
Topics: Animals; Carcinogens; Chromatin; DNA; Methylation; Models, Biological; Neoplasms, Experimental; Nickel; Phagocytosis | 1995 |
Hypomethylation of DNA: an epigenetic mechanism involved in tumor promotion.
Topics: Animals; DNA; DNA, Neoplasm; Gene Expression; Methylation; Mice; Neoplasms; Neoplasms, Experimental; Oncogenes | 1994 |
Genomic imprinting, DNA methylation, and cancer.
Topics: Animals; Beckwith-Wiedemann Syndrome; DNA, Neoplasm; Genomic Imprinting; Humans; Methylation; Models, Genetic; Neoplasms; Neoplasms, Experimental; Pedigree | 1995 |
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Cysteine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Protein Kinase C; Proteins; Selenium; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors | 1999 |
New aspects of brain tumor research.
Topics: Alkylation; Animals; Brain Neoplasms; DNA; Humans; Methylation; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds | 1977 |
Biological significance of methylated derivatives of lysine and arginine.
Topics: Animals; Arginine; Blood Pressure; Cell Division; Cytochrome c Group; Histones; Lysine; Methylation; Muscle Proteins; Neoplasms, Experimental; Proteins; Structure-Activity Relationship | 1977 |
Methylation, mutation and cancer.
Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplasm; Female; Genes, p53; Genetic Diseases, Inborn; Humans; Male; Methylation; Mutation; Neoplasms; Neoplasms, Experimental; Vertebrates | 1992 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic Acid Deficiency; Humans; Immunity, Cellular; Lipotropic Agents; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms; Neoplasms, Experimental; Pharmaceutical Preparations; Risk; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
The regulation of albumin and alpha-fetoprotein gene expression in mammals.
Topics: Albumins; alpha-Fetoproteins; Animals; DNA; Gene Expression Regulation; Genes; Growth; Humans; Liver; Methylation; Models, Biological; Neoplasms, Experimental; Regulatory Sequences, Nucleic Acid; Transcription, Genetic | 1987 |
Chemical xenogenization of experimental tumors.
Topics: Animals; Antigens, Neoplasm; Carmustine; Cell Line; Dacarbazine; DNA; Histocompatibility Antigens; Immunotherapy; Methylation; Methylnitronitrosoguanidine; Neoplasms, Experimental; T-Lymphocytes, Cytotoxic; Triazenes | 1987 |
Genetic instability and tumor progression.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Clone Cells; DNA, Neoplasm; Gene Expression Regulation; Humans; Methylation; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Oncogenes; Precancerous Conditions | 1986 |
The biological modification of tumor cells as a means of inducing their regression: an overview.
Topics: Animals; Antibodies, Neoplasm; Antibodies, Viral; Cricetinae; DNA, Neoplasm; Guinea Pigs; Hybrid Cells; Immunotherapy; Methylation; Mice; Mutagens; Mutation; Neoplasms, Experimental; Rats; Ultraviolet Therapy; Virus Diseases | 1986 |
Dietary methyl groups and cancer.
Topics: Animals; Choline Deficiency; Diet; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats | 1986 |
[Role of enzymatic DNA methylation in cell differentiation and carcinogenesis].
Topics: Animals; Base Composition; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; DNA; DNA, Neoplasm; Gene Expression Regulation; Methylation; Methyltransferases; Neoplasms, Experimental; Transcription, Genetic | 1985 |
[Methylation of nucleic acids under normal conditions and in leukemia. Literature survey and personal data].
Topics: Animals; Cricetinae; DNA; DNA Nucleotidyltransferases; DNA-Directed RNA Polymerases; DNA, Neoplasm; Humans; Leukemia; Lymphocytes; Methylation; Mice; Neoplasms, Experimental; Nucleic Acid Conformation; Rats; RNA; RNA, Neoplasm; RNA, Ribosomal | 1973 |
Role of the methylated nucleic acids in carcinogenesis.
Topics: Animals; DNA, Neoplasm; Humans; Leukemia; Leukemia, Experimental; Methylation; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acids; RNA, Neoplasm; Species Specificity; Transferases | 1969 |
Formation, functions and regulatory importance of S-adenosyl-L-methionine.
Topics: Adenosine; Adenosine Triphosphate; Alkanes; Alkenes; Alkynes; Amino Acids; Animals; Antineoplastic Agents; Binding Sites; Carbon Isotopes; Carboxylic Acids; Cyclopentanes; Escherichia coli; Homocysteine; Homoserine; Kinetics; Liver; Methionine; Methylation; Mice; Neoplasms, Experimental; Rats; Spleen; Transferases; Tritium; Yeasts | 1970 |
181 other study(ies) available for isomethyleugenol and Experimental Neoplasms
| Article | Year |
|---|---|
Targeted methylation facilitates DNA double strand breaks and enhances cancer suppression: A DNA intercalating/methylating dual-action chimera Amonafidazene.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Organophosphonates; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
The correlation between the methylation of PTEN gene and the apoptosis of osteosarcoma cells mediated by SeHA nanoparticles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Durapatite; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Osteosarcoma; Particle Size; PTEN Phosphohydrolase; Selenium; Surface Properties; Tumor Cells, Cultured | 2019 |
Novel regulator role of CIL-102 in the epigenetic modification of TNFR1/TRAIL to induce cell apoptosis in human gastric cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Quinolines; Receptors, Tumor Necrosis Factor, Type I; Stomach Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2021 |
Synthesis of L-[5-
Topics: Animals; Carbon Radioisotopes; Catalysis; Cell Line, Tumor; Humans; Hydrogenation; Leucine; Methylation; Mice; Molecular Probes; Molecular Structure; Neoplasms, Experimental; Palladium; Positron-Emission Tomography | 2021 |
Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice.
Topics: Animals; Carcinoma; Cholesterol; Diet, High-Fat; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histones; Homeodomain Proteins; Humans; Liver X Receptors; Male; Methylation; Mice; Mice, Knockout; Neoplasms, Experimental; Orphan Nuclear Receptors; Polycomb Repressive Complex 2; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Prostatic Secretory Proteins; Transcription Factors | 2013 |
Development of multiple cell-based assays for the detection of histone H3 Lys27 trimethylation (H3K27me3).
Topics: Batch Cell Culture Techniques; Biological Assay; Biosensing Techniques; Cell Line, Tumor; Equipment Design; Equipment Failure Analysis; High-Throughput Screening Assays; Histamine H3 Antagonists; Histones; Humans; Immunoassay; Methylation; Neoplasms, Experimental; Tissue Array Analysis | 2013 |
A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Fibrosarcoma; Glutaminase; Glutarates; HEK293 Cells; High-Throughput Screening Assays; Histones; Humans; Isocitrate Dehydrogenase; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Purinones | 2014 |
Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation.
Topics: Animals; Apoptosis Regulatory Proteins; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Lung Neoplasms; Methylation; Mice; Neoplasms, Experimental; Repressor Proteins; Transcription, Genetic; Tripartite Motif-Containing Protein 28 | 2014 |
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Topics: Adenosine; Animals; Bone Marrow Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasms, Experimental; Nuclear Pore Complex Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Phenylurea Compounds; Transcription Factors | 2014 |
Automethylation of protein arginine methyltransferase 7 and its impact on breast cancer progression.
Topics: Animals; Breast Neoplasms; Female; Gene Deletion; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; Protein-Arginine N-Methyltransferases | 2017 |
PRIMA-1MET inhibits growth of mouse tumors carrying mutant p53.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aza Compounds; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; In Situ Nick-End Labeling; Methylation; Mice; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2008 |
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.
Topics: Adrenomedullin; Animals; Cell Hypoxia; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation; Growth Differentiation Factor 15; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Male; Methylation; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Transplantation, Heterologous | 2010 |
Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; DNA Primers; Enzyme-Linked Immunosorbent Assay; Histocompatibility Antigens Class I; Human papillomavirus 16; Immunotherapy; Male; Methylation; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction | 2011 |
Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.
Topics: Animals; Blotting, Western; Cell Proliferation; Cluster Analysis; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; HCT116 Cells; Histone Demethylases; Histones; Humans; Lysine; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2013 |
Medical hypothesis: hyperhomocysteinemia is a risk factor for estrogen-induced hormonal cancer.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Estradiol; Estrogens; Estrogens, Catechol; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kinetics; Methylation; Models, Biological; Mutagenicity Tests; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Risk Factors; S-Adenosylhomocysteine; Uterine Neoplasms; Vitamin B 12; Vitamin B 6 | 2003 |
Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes.
Topics: Adenoviruses, Human; Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Gene Expression Profiling; Humans; Injections, Intramuscular; Mesocricetus; Methylation; Mice; Neoplasms, Experimental; Neuroectodermal Tumors; Oligonucleotide Array Sequence Analysis; Peritoneal Cavity; Proteins; Sequence Analysis, DNA; Transcription, Genetic; Viral Proteins; Virus Integration | 2003 |
Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cricetinae; DNA, Neoplasm; Karyotyping; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Trisomy | 1983 |
5-azacytidine induction of thymidine kinase in a spontaneously enzyme-deficient murine tumor line.
Topics: Animals; Azacitidine; Cell Division; Cell Line; DNA, Neoplasm; Enzyme Induction; Methylation; Mice; Neoplasms, Experimental; Thymidine Kinase | 1984 |
Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; DNA, Neoplasm; Methylation; Mice; Neoplasm Metastasis; Neoplasms, Experimental | 1984 |
The tumorigenicity of 5-azacytidine in the male Fischer rat.
Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms | 1984 |
Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes.
Topics: Aging; Animals; Brain; Carcinoma, Ehrlich Tumor; Cell Line; Female; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains; Sarcoma 180; Sarcoma, Yoshida; Tissue Distribution | 1984 |
Shope papilloma virus DNA is extensively methylated in non-virus-producing neoplasms.
Topics: Animals; Cottontail rabbit papillomavirus; DNA Restriction Enzymes; DNA, Viral; Methylation; Molecular Weight; Neoplasms, Experimental; Nucleic Acid Hybridization; Papillomaviridae; Rabbits; Tumor Virus Infections | 1983 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Role of de novo DNA methylation in the glucocorticoid resistance of a T-lymphoid cell line.
Topics: Animals; Cell Line; Clone Cells; Dexamethasone; DNA, Neoplasm; Drug Resistance; Lymphoma; Methylation; Mice; Mice, Inbred AKR; Neoplasms, Experimental; T-Lymphocytes; Thymus Neoplasms | 1983 |
Loss of viral genomes from hamster tumor cells and nonrandom alterations in patterns of methylation of integrated adenovirus type 12 DNA.
Topics: Adenoviruses, Human; Animals; Cell Line; Cricetinae; DNA, Viral; Genes, Viral; Methylation; Neoplasms, Experimental; Recombination, Genetic; RNA, Viral | 1983 |
Methylation and rearrangement of mouse intracisternal a particle genes in development, aging, and myeloma.
Topics: Aging; Animals; Base Sequence; DNA, Neoplasm; Gene Expression Regulation; Genes, Viral; Liver; Methylation; Mice; Neoplasms, Experimental; Plasmacytoma; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Retroviridae | 1983 |
Comparison of repair of O6-methylguanine produced by N-methyl-N'-nitro-N-nitrosoguanidine in mouse and human cells.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; DNA Repair; Embryo, Mammalian; Female; Guanine; Humans; Kinetics; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Neoplasms; Neoplasms, Experimental; Species Specificity | 1984 |
In vitro methylation of total and foldback DNAs in normal and virus-transformed cells.
Topics: Animals; Base Sequence; Cell Cycle; Cell Transformation, Viral; Cells, Cultured; DNA; DNA, Neoplasm; Methylation; Mice; Neoplasms, Experimental; Rats; Repetitive Sequences, Nucleic Acid | 1984 |
Methylation-like reaction of [3H-methyl]-N-5-trimethyllysine (TML) to chromatin components.
Topics: Animals; Chromatin; DNA; Lysine; Methylation; Mice; Molecular Weight; Neoplasms, Experimental | 1980 |
Inhibition of S-adenosylmethionine-linked methylation can lead to neurite extension in neuroblastoma cells.
Topics: Animals; Calcimycin; Clone Cells; Methylation; Mice; Neoplasms, Experimental; Neuroblastoma; Neurons; Phospholipids; Quinacrine; S-Adenosylmethionine | 1982 |
Autoimmune haemolytic disease in mice after exposure to a methylating carcinogen.
Topics: Anemia, Hemolytic, Autoimmune; Animals; DNA; Dose-Response Relationship, Drug; Guanine; Methyl Methanesulfonate; Methylation; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Species Specificity; Spleen; Thymoma; Thymus Neoplasms | 1983 |
Persistence of methylated purines in the DNA of various rat fetal and maternal tissues and carcinogenesis in the offspring following a single transplacental dose of N-methyl-N-nitrosourea.
Topics: Adenine; Animals; Brain; DNA; Female; Fetus; Guanine; Kidney; Liver; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Purines; Rats; Time Factors | 1983 |
Carcinogenicity of deuterium-labeled N-nitroso-N-methylcyclohexylamine in rats.
Topics: Animals; Carcinogens; Cyclohexylamines; Deuterium; Esophageal Neoplasms; Female; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344 | 1980 |
Effects of 8-azaadenosine and formycin on cell lethality and the synthesis and methylation of nucleic acids in human colon carcinoma cells in culture.
Topics: Adenosine; Antibiotics, Antineoplastic; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Formycins; Humans; Methylation; Neoplasms, Experimental; RNA, Neoplasm | 1982 |
Studies of a deuterium isotope effect in carcinogenesis by N-nitroso-N-alkylurethanes in rats.
Topics: Animals; Carcinogens; Deuterium; Esophageal Neoplasms; Female; Liver Neoplasms; Methylation; Neoplasms, Experimental; Nitrosomethylurethane; Rats; Rats, Inbred F344; Stomach Neoplasms; Urethane | 1982 |
Hypomethylation of DNA in Raji cells after treatment with N-methyl-N-nitrosourea.
Topics: Burkitt Lymphoma; Cell Division; Cell Line; DNA; Humans; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds | 1981 |
Metabolic fate of N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Chromatography, Thin Layer; Hydrolysis; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1980 |
Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis.
Topics: Alkylation; Animals; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA; DNA Repair; Liver; Liver Neoplasms; Mesocricetus; Methylation; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Structure-Activity Relationship | 1981 |
Comparative tumor-initiating activity of methylated benzo(a)pyrene derivatives in mouse skin.
Topics: Animals; Benzopyrenes; Cocarcinogenesis; Female; Methylation; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Characterization of adenosine-induced cytostasis in melanoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Count; Cell Division; Cell Line; Guanosine; Homocysteine; Melanoma; Methylation; Mice; Neoplasms, Experimental; Pyrimidines; RNA, Neoplasm; Uridine | 1980 |
Phospholipid methylation in MOPC-31C cell membranes with modified phospholipid composition.
Topics: Cell Line; Choline; Membrane Lipids; Methylation; Neoplasms, Experimental; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Plasmacytoma | 1980 |
Effect of methionine deprivation on methylation and synthesis of macromolecules.
Topics: Animals; Cell Line; DNA, Neoplasm; Homocysteine; Humans; Macromolecular Substances; Methionine; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm | 1980 |
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis.
Topics: Animals; Base Sequence; Cell Division; Cells, Cultured; DNA; DNA Modification Methylases; Male; Methylation; Mice; Molecular Sequence Data; Neoplasms, Experimental; RNA, Antisense; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1995 |
Inhibition of hepatitis B virus surface antigen gene expression in carcinogen-induced liver tumors from transgenic mice.
Topics: Animals; Carcinogens; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Hepatitis B Surface Antigens; Liver Neoplasms; Male; Methylation; Mice; Mice, Transgenic; Neoplasms, Experimental; RNA, Messenger; RNA, Neoplasm | 1994 |
Effects of methyl substitutions on benz[a]anthracene derivatives-induced immunosuppression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Benz(a)Anthracenes; Carcinogens; CD3 Complex; Cell Cycle; Cell Division; Concanavalin A; Female; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Interleukin-6; Lethal Dose 50; Methylation; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Receptors, Interleukin-2; Signal Transduction; Spleen; Structure-Activity Relationship; T-Lymphocytes | 1996 |
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured | 2000 |
[On the carcinogenetic action of N-nitroso compounds. 7th communication: methyl-, trideuteromethyl-, ethyl-, n-propyl-, n-butyl-, acetoxymethyl-nitrosamine, and methyl-butyroxymethyl-nitrosamine (author's transl)].
Topics: Alkylation; Animals; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Female; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; Stomach Neoplasms; Time Factors | 1978 |
Interrelationships between synthesis and methylation of ribosomal RNA in isolated Novikoff Tumor nucleoli.
Topics: Animals; Carcinoma, Hepatocellular; Cations, Divalent; Cell Nucleolus; DNA-Directed RNA Polymerases; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer; Transcription, Genetic; tRNA Methyltransferases | 1975 |
Sulfhydryl group quantitation of hepatoma and liver microsomal fractions.
Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Disulfides; Edetic Acid; Endoplasmic Reticulum; Female; Iodamide; Liver; Liver Neoplasms; Male; Methylation; Microsomes, Liver; Neoplasms, Experimental; Polyribosomes; Potassium Chloride; Protein Binding; Protein Conformation; Pyridines; Rats; Sex Factors; Sulfhydryl Compounds; Sulfhydryl Reagents; Urea | 1975 |
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine | 1975 |
Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Liver Neoplasms; Methylation; Neoplasms, Experimental; Poly A; Rats; RNA, Messenger; RNA, Neoplasm; Waxes | 1975 |
Interaction of normal and tumor transfer RNA methyltransferases with ethionine-induced methyl-deficient rat liver transfer RNA.
Topics: Animals; Carcinoma, Hepatocellular; Escherichia coli; Ethionine; Female; Kinetics; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Transfer; tRNA Methyltransferases | 1975 |
The topographical order of 18 S and 20 S ribosomal ribonucleic acids within the 45 S precursor molecule.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; Ribosomes; RNA, Neoplasm; RNA, Ribosomal | 1975 |
Tissue specific differences in the 2'-O-methylation of eukaryotic 5.8S ribosomal RNA.
Topics: Animals; Carcinoma, Hepatocellular; Guanine Nucleotides; Humans; Liver; Liver Neoplasms; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Ribosomal; Structure-Activity Relationship; Uracil Nucleotides; Uridine Monophosphate | 1975 |
Kinetics of Novikoff cytoplasmic messenger RNA methylation.
Topics: Carcinoma, Hepatocellular; Cell Line; Cytoplasm; Kinetics; Liver Neoplasms; Methylation; Neoplasms, Experimental; Oligoribonucleotides; Ribonucleosides; Ribonucleotides; RNA, Messenger | 1976 |
Inhibition of RNA methylation by intercalating agents.
Topics: Alkaloids; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Ellipticines; Ethidium; Hycanthone; In Vitro Techniques; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer; Thioxanthenes; tRNA Methyltransferases | 1977 |
Tumour-specific phenylalanine tRNA contains two supernumerary methylated bases.
Topics: Animals; Base Sequence; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Liver Neoplasms; Methylation; Mice; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; tRNA Methyltransferases | 1978 |
Lack of involvement of 6-hydroxymethylation in benzo[a]pyrene skin tumor initiation in mice.
Topics: Animals; Benzimidazoles; Benzopyrenes; Biotransformation; Female; Flavonoids; Hydroxylation; Methylation; Mice; Neoplasms, Experimental; Papilloma; Quercetin; Skin Neoplasms | 1978 |
[Molecular biology and clinical significance of the metabolism of normal and modified nucleobases (author's transl)].
Topics: Animals; Base Sequence; Cells, Cultured; Chemical Phenomena; Chemistry; DNA; Humans; Kidney Neoplasms; Leukemia; Leukemia, Experimental; Liver; Liver Regeneration; Methylation; Mice; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; tRNA Methyltransferases | 1977 |
Carcinogenicity of methylated derivatives of N-nitrosodiethylamine and related compounds in Sprague-Dawley rats.
Topics: Animals; Carcinogens; Diethylnitrosamine; Esophageal Neoplasms; Female; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; Rats; Structure-Activity Relationship | 1979 |
The mechanism of action of tRNA methylases studied with immobilized tRNAs.
Topics: Animals; Kidney Neoplasms; Kinetics; Liver Neoplasms, Experimental; Methylation; Neoplasms, Experimental; Rats; RNA, Transfer; Substrate Specificity; tRNA Methyltransferases | 1979 |
Carcinogenic azo dyes--detection of new metabolites of 3'-methyl-4-(methylamino)azobenzene in rat bile.
Topics: Animals; Azo Compounds; Bile; Carcinogens; Ions; Isotope Labeling; Liver Neoplasms; Male; Methods; Methylation; Neoplasms, Experimental; p-Aminoazobenzene; Rats; Tritium | 1979 |
Cytotoxic saponins from the Chinese herbal drug Yunnan Bai Yao.
Topics: Animals; Antineoplastic Agents, Phytogenic; China; Humans; Hydrolysis; In Vitro Techniques; Methylation; Mice; Molecular Conformation; Neoplasms, Experimental; Plant Extracts; Saponins | 1979 |
Mechanism of perinatal tumor induction by neuro-oncogenic alkylnitrosoureas and dialkylaryltriazenes.
Topics: Animals; Brain; DNA; DNA Repair; Female; Fetus; Guanine; Liver; Maternal-Fetal Exchange; Methylation; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Pregnancy; Rats; Triazenes | 1979 |
Correlation of DNA methylation by methyl(acetoxymethyl)nitrosamine with organ-specific carcinogenicity in rats.
Topics: Animals; Biotransformation; Dimethylnitrosamine; DNA; Lung; Male; Methylation; Neoplasms, Experimental; Organ Specificity; Rats | 1979 |
5-methylcytosine content of DNA during differentiation in mouse teratocarcinoma cells.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cytosine Nucleotides; DNA, Neoplasm; Fibroblasts; Methylation; Mice; Muscles; Neoplasms, Experimental; Teratoma | 1979 |
Tumor initiating activity of 5,11-dimethylchrysene and the structural requirements favoring carcinogenicity of methylated polynuclear aromatic hydrocarbons.
Topics: Animals; Chrysenes; Female; Methylation; Mice; Neoplasms, Experimental; Phenanthrenes; Polycyclic Compounds; Skin Neoplasms; Structure-Activity Relationship | 1979 |
Methylation of DNA in mouse early embryos, teratocarcinoma cells and adult tissues of mouse and rabbit.
Topics: Animals; Base Sequence; Blastocyst; Cytosine; DNA; DNA, Neoplasm; Embryo, Mammalian; Female; Male; Methylation; Mice; Neoplasms, Experimental; Pregnancy; Rabbits; Sex Factors; Species Specificity; Teratoma; Tissue Distribution | 1979 |
DNA alkylation in mice with genetically different susceptibility to 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: Animals; Biotransformation; Colon; Colonic Neoplasms; Dimethylhydrazines; DNA; Ileum; Kidney; Liver; Male; Methylation; Methylhydrazines; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Neoplasms, Experimental; Purines; Species Specificity | 1978 |
Studies on the uptake of N-E-3H-trimethyl-L-lysine in the organs of mice with NK/Ly ascites tumors.
Topics: Animals; Ascites; Biological Transport; Chromatography, Thin Layer; Extracellular Space; Female; Lysine; Methylation; Mice; Neoplasms, Experimental; Tissue Distribution | 1978 |
Carbon-11-labeled methylated polyamine analogs: uptake in prostate and tumor in animal models.
Topics: Animals; Carbon Radioisotopes; Dogs; Male; Melanoma; Methylation; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Polyamines; Prostatic Neoplasms; Putrescine; Radionuclide Imaging; Rats; Spermidine; Spermine; Tomography | 1977 |
Possible repair of carcinogenic damage caused by dimethylnitrosamine in rat kidney.
Topics: Animals; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Kidney Neoplasms; Methylation; Neoplasms, Experimental; Nitrosamines; Rats | 1976 |
Tumorigenicity of tetramethylhydrazine hydrochloride in Swiss mice.
Topics: Adenoma; Animals; Carcinogens; Female; Hemangioma; Hemangiosarcoma; Hydrazines; Kidney Neoplasms; Lung Neoplasms; Male; Methylation; Methylhydrazines; Mice; Monomethylhydrazine; Neoplasms, Experimental; Structure-Activity Relationship | 1976 |
Carcinogenicity of methylated nitrosopiperidines.
Topics: Animals; Carcinogens; Female; Gastrointestinal Neoplasms; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; Nitroso Compounds; Nose Neoplasms; Piperidines; Rats; Structure-Activity Relationship; Time Factors | 1975 |
Evidence of extensive phospholipid fatty acid methylation during the assumed selective methylation of plasma free fatty acids by diazomethane.
Topics: Animals; Blood Chemical Analysis; Chromatography; Colorimetry; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Phospholipids | 1991 |
Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet.
Topics: Animals; Choline Deficiency; Diet; DNA; ErbB Receptors; Gene Expression; Liver; Male; Methionine; Methylation; Neoplasms, Experimental; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA, Messenger; Vitamin B 12 Deficiency | 1991 |
Induction of thymidine kinase activity in a spontaneously enzyme-deficient murine tumor cell line by exposure in vivo to the DNA-hypomethylating agent 5-aza-2'-deoxycytidine: implications for mechanisms of tumor progression.
Topics: Animals; Azacitidine; Cell Line; Decitabine; DNA; Enzyme Induction; Male; Methylation; Mice; Mice, Inbred DBA; Mutation; Neoplasms, Experimental; Thymidine Kinase | 1985 |
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1986 |
On the possible contribution of DNA hypomethylation to the induction of high frequency and heritable drug-induced alterations in the malignant phenotype.
Topics: Alkylating Agents; Animals; Azacitidine; Cell Line; DNA, Neoplasm; Gene Amplification; Humans; Methylation; Mice; Mutagens; Mutation; Neoplasms; Neoplasms, Experimental; Phenotype; Thymidine Kinase | 1986 |
Suppression of tumorigenicity mediated by 5-azacytidine and associated with increased chromosome number.
Topics: Animals; Azacitidine; Cell Line; Chromosomes; DNA, Neoplasm; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental | 1987 |
Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells.
Topics: Adenoviruses, Human; Animals; Azacitidine; Cell Division; Cell Transformation, Viral; Cells, Cultured; DNA, Neoplasm; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mice; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Transcription, Genetic | 1985 |
Rapid appearance of hypomethylated DNA in livers of rats fed cancer-promoting, methyl-deficient diets.
Topics: Animals; Choline Deficiency; DNA; Folic Acid Deficiency; Liver; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; RNA, Transfer; Vitamin B 12 Deficiency | 1989 |
Expression and methylation of the Blym gene in human tumor cell lines.
Topics: Cell Line; DNA Restriction Enzymes; DNA, Neoplasm; Electrophoresis, Agar Gel; Genes; Humans; Methylation; Neoplasms, Experimental; Nucleic Acid Hybridization; RNA, Messenger; RNA, Neoplasm | 1987 |
Insertion of adenovirus type 12 DNA in the vicinity of an intracisternal A particle genome in Syrian hamster tumor cells.
Topics: Adenoviridae; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cricetinae; DNA Transposable Elements; DNA, Viral; Genes, Intracisternal A-Particle; Mesocricetus; Methylation; Neoplasms, Experimental; Proto-Oncogenes; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1987 |
Characterization of a tumorigenic murine T-lymphoid-cell line spontaneously derived from an IL-2-dependent T-cell line.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Interleukin-2; Karyotyping; Methylation; Mice; Neoplasms, Experimental; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes, Cytotoxic | 1986 |
Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
Topics: Animals; Carcinogens; Diet; DNA; Glucosinolates; Indoles; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Methyltransferases; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Thioglycosides | 1988 |
Comparative carcinogenesis by nitrosomethylalkylamines in Syrian hamsters.
Topics: Animals; Cricetinae; DNA; Female; Male; Mesocricetus; Methylation; Neoplasms, Experimental; Nitrosamines; Structure-Activity Relationship | 1988 |
Eukaryotic DNA methyltransferase: tissue and species distribution.
Topics: Animals; Cross Reactions; Digestive System; DNA; DNA (Cytosine-5-)-Methyltransferases; Kidney; Methylation; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Organ Specificity; Species Specificity; Substrate Specificity | 1988 |
Differential effect of dietary methionine on the biopotency of selenomethionine and selenite in cancer chemoprevention.
Topics: Animals; Diet; Female; Methionine; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenomethionine | 1988 |
Carcinogenesis and nucleic acid alkylation by some oxygenated nitrosamines in rats and hamsters.
Topics: Administration, Oral; Alkylation; Animals; Cricetinae; Diethylnitrosamine; DNA; Liver Neoplasms; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Species Specificity; Stomach | 1988 |
Double restriction in NK cell recognition is linked to transmethylation and can be triggered by asparagine-linked oligosaccharides on tumor cells.
Topics: Animals; Carbohydrates; Cells, Cultured; Cytotoxicity, Immunologic; Immunity, Cellular; Immunity, Innate; In Vitro Techniques; Killer Cells, Natural; Membrane Lipids; Methylation; Mice; Neoplasms, Experimental; Phospholipids; Receptors, Immunologic; Tunicamycin | 1987 |
[Characteristics of the carcinogenic action of methyl(acetoxymethyl)nitrosamine and DNA repair in rats of different ages].
Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Repair; Female; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1986 |
Asn-linked oligosaccharides in lectin-resistant tumor-cell mutants with varying metastatic potential.
Topics: Asparagine; Cell Line; Chromatography, Affinity; Chromatography, High Pressure Liquid; Concanavalin A; Lectins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Mutation; Neoplasms, Experimental; Oligosaccharides; Phenotype | 1986 |
Effect of age on DNA repair in carcinogenesis due to alkylating agents.
Topics: Age Factors; Aging; Alkylating Agents; Animals; Dimethylnitrosamine; DNA; DNA Repair; Liver; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1985 |
Tumor-initiating activity, mutagenicity, and metabolism of methylated anthracenes.
Topics: Anthracenes; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Methylation; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Salmonella typhimurium; Skin Neoplasms; Spectrum Analysis; Structure-Activity Relationship | 1985 |
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats | 1986 |
[Effect of age on carcinogenesis in female rats induced by methyl (acetoxymethyl) nitrosamine].
Topics: Aging; Alkylation; Animals; Carcinogens; Dimethylnitrosamine; DNA, Neoplasm; Male; Methylation; Neoplasms, Experimental; Purines; Rats; Time Factors; Tissue Distribution | 1985 |
Study of DNA methylation by tobacco-specific N-nitrosamines.
Topics: Animals; Antibodies; Carcinogens; Cells, Cultured; Deoxyguanosine; Deoxyribonucleosides; DNA; Enzyme-Linked Immunosorbent Assay; Methylation; Mucous Membrane; Nasal Mucosa; Neoplasms, Experimental; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Smoking | 1985 |
Unmasking of proteins by in vitro methylation of rat liver RNA during azo dye carcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coloring Agents; Cytoplasm; Histocytochemistry; Liver; Liver Neoplasms; Methods; Methylation; Microscopy; Neoplasm Proteins; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Proteins; Rats; RNA; RNA, Neoplasm; Staining and Labeling; Temperature | 1971 |
Transfer RNA methylase activity in normal monkey liver and in carcinogen-induced hepatoma.
Topics: Alpha-Globulins; Animals; Carcinogens; Carcinoma, Hepatocellular; Chromatography; Female; Fetal Proteins; Haplorhini; Liver; Liver Neoplasms; Macaca; Male; Methylation; Neoplasms, Experimental; Nitroso Compounds; Ribonucleases; RNA, Neoplasm; RNA, Transfer | 1971 |
Early appearance of serum -fetoprotein during hepatocarcinogenesis as a function of age of rats and extent of treatment with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Age Factors; Alpha-Globulins; Animals; Carcinoma, Hepatocellular; Immunodiffusion; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Thiocyanates | 1972 |
[Bioantioxidants as regulators of oxidative free radical processes at various stages of hepatic carcinogenesis].
Topics: Adenocarcinoma; Aniline Compounds; Animals; Antioxidants; Azo Compounds; Chemistry, Organic; Esters; Free Radicals; Kinetics; Lipid Mobilization; Liver Neoplasms; Luminescence; Male; Methylation; Neoplasms, Experimental; Oleic Acids; Organic Chemistry Phenomena; Oxygen Consumption; p-Dimethylaminoazobenzene; Rats | 1972 |
Oxidative activation of benz(a)anthracene and methylated derivatives in mutagenesis and carcinogenesis.
Topics: Animals; Benz(a)Anthracenes; Dose-Response Relationship, Drug; Drosophila melanogaster; Ethers, Cyclic; Genes; Male; Methylation; Methylcholanthrene; Mutagens; Mutation; Neoplasms, Experimental; Oxidation-Reduction; RNA, Ribosomal; Sex Chromosomes; Skin Neoplasms; Spermatozoa | 1973 |
Suppressive effect of concurrent administration of metal salts on carcinogenesis by 3'-methyl-4-(dimethylamino)azobenzene, and the effect of these metals on aminoazo dye metabolism during carcinogenesis.
Topics: Animals; Body Weight; Copper; Female; Hydroxylation; Liver; Liver Neoplasms; Manganese; Metals; Methylation; Neoplasms, Experimental; Nickel; p-Dimethylaminoazobenzene; Protein Binding; Rats; Zinc | 1973 |
[The organotropy of alkylating activity of dimethylnitrosamine (DMNA) and nitrosomethyl urea (NMH) in vivo].
Topics: Alkylating Agents; Animals; Body Weight; Carbon Isotopes; Female; Formates; Guanine; Hepatectomy; Injections, Intravenous; Kidney; Liver; Lymphoma, Large B-Cell, Diffuse; Male; Methanol; Methylation; Mice; Muscles; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosourea Compounds; Rats; RNA; RNA, Neoplasm; Salmonidae; Sarcoma, Experimental; Urea | 1970 |
Fractionation of nuclear ribonucleic acids from tumor and homologous tissue on a methylated albumin column by the use of salt and temperature gradients.
Topics: Albumins; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA; RNA, Neoplasm; Sodium Chloride; Temperature | 1967 |
Methylation of DNA in vitro: enzymic activity from different bacterial strains on DNA from various sources.
Topics: Adenocarcinoma; Animals; Azotobacter; Carbon Isotopes; Chromatography, Paper; DNA; DNA, Bacterial; DNA, Neoplasm; DNA, Viral; Escherichia coli; Ethionine; Heparin; Lymphoma, Non-Hodgkin; Methionine; Methylation; Mice; Neoplasms, Experimental; Peptides; Polyomavirus | 1967 |
Hepatotoxic and carcinogenic effects of dimethylnitrosamine in low dosage. Light and electron microscopic study.
Topics: Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Liver; Liver Neoplasms; Methylation; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Rats | 1968 |
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides | 1968 |
Biochemical, pathological, and genetic aspects of a spontaneous mouse hepatoma.
Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Diet; Fatty Liver; Female; Hybridization, Genetic; Karyotyping; L-Serine Dehydratase; Liver; Liver Neoplasms; Male; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; Sex Factors; Transaminases; Transferases; Vitamin E | 1969 |
Studies on DNA methylase activity in mammalian tissue.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Edetic Acid; Liver; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Quaternary Ammonium Compounds; Salmonidae; Testis; Transferases | 1969 |
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine | 1969 |
The effects of local x irradiation on the relative rates of incorporation of thymidine-methyl-5-3H and cytidine-5-3H into mitochondrial and nuclear DNA of Morris hepatoma 3924A.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver Neoplasms; Methylation; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Radiography; Radiotherapy Dosage; Rats; Thymidine; Tritium | 1969 |
Transfer RNA from tumor tissue.
Topics: Animals; Burkitt Lymphoma; Carbon Isotopes; Connective Tissue; Cricetinae; Culture Techniques; Humans; Liver; Lymphocytes; Methylation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; RNA, Transfer; Simian virus 40; Thymus Gland; Transferases | 1969 |
Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Densitometry; Electrophoresis; Formates; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleotides; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides | 1969 |
Natural inhibitors of the transfer ribonucleic acid methylases.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Dialysis; Drug Stability; Escherichia coli; Female; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Omentum; Pregnancy; Quaternary Ammonium Compounds; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Trypsin; Ultracentrifugation | 1970 |
Histone methylase activity of adult, embryonic and neoplastic liver tissues.
Topics: Animals; Brain; Carcinoma, Hepatocellular; Cattle; Fetus; Histones; Kidney; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rabbits; RNA; Spleen; Transferases | 1970 |
Methylation of preribosomal and transfer RNA's by isolated nucleoli of the Novikoff rat tumor.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Transfer; Tritium | 1970 |
Change of glycolipid pattern in Morris hepatomas 5123 and 7800.
Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Glycolipids; Liver; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; Neuraminic Acids; Rats | 1970 |
Agents of modulation of the transfer RNA methylases.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Castration; Chromatography; Chromatography, Gel; Enzyme Inhibitors; Estradiol; Female; Guanine; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Methylation; Methyltransferases; Molecular Weight; Neoplasms, Experimental; Rabbits; Rats; RNA, Transfer; Swine; Transferases; Uterus | 1971 |
Methylation of transfer RNA by monkey liver and hepatoma induced by N-nitrosodiethylamine.
Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Escherichia coli; Fetal Proteins; Haplorhini; Liver; Liver Extracts; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nitrosamines; RNA, Bacterial; RNA, Transfer | 1971 |
Methylation of mammalian deoxyribonucleic acid. II. The distribution of 5-methylcytosine in pyrimidine deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.
Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Techniques; Cytosine; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA, Neoplasm; Formates; Hydrolysis; Liver Neoplasms; Methionine; Methods; Methylation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; Snakes; Spectrophotometry; Thymine Nucleotides; Venoms | 1971 |
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors | 1971 |
Protein methylases in hepatomas.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Histones; Liver Neoplasms; Methylation; Methyltransferases; Neoplasm Proteins; Neoplasms, Experimental; Rats; S-Adenosylmethionine | 1972 |
Altered regulation of the transport of RNA from nucleus to cytoplasm in rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Fetus; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; RNA, Neoplasm | 1972 |
Influence of age and sex on hepatic lesions induced by chemical carcinogens: ingestion of 3'-methyl-4-dimethylaminoazobenzene by Buffalo strain rats.
Topics: Adenoma, Bile Duct; Age Factors; Animals; Carcinoma, Hepatocellular; Female; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Sex Factors | 1972 |
Methylation of mammalian deoxyribonucleic acid. 3. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff hepatoma cell deoxyribonucleic acid.
Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Clone Cells; Cytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Escherichia coli; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats; Spleen; Venoms | 1972 |
-Glutamyl transpeptidase in transplantable, chemically induced rat hepatomas and "spontaneous" mouse hepatomas.
Topics: Acyltransferases; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Colorimetry; Cysteine; Female; Fetus; Glutathione; Hydro-Lyases; Liver Neoplasms; Male; Methylation; Neoplasm Transplantation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Polarography; Rats | 1972 |
Specific enhancement of hepatoma growth using methylated bovine serum albumin and pertussis vaccine.
Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Membrane; Female; Immunity, Cellular; Liver Neoplasms; Methylation; Neoplasms, Experimental; Pertussis Vaccine; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1972 |
[Experimental pancreatic tumor].
Topics: Adenoma, Islet Cell; Animals; Carcinogens; Cyclic N-Oxides; Dogs; Guinea Pigs; Methylation; Neoplasms, Experimental; Niacinamide; Nitrosourea Compounds; Pancreatic Neoplasms; Quinolines; Rats; Streptozocin | 1972 |
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency | 1972 |
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen | 1972 |
Inhibition of transfer and ribosomal RNA methylases by polyinosinate.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleolus; Inosine Nucleotides; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Polynucleotides; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer | 1973 |
1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.
Topics: Acetylation; Administration, Oral; Allyl Compounds; Animals; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Dioxoles; Female; Hemangiosarcoma; Hydroxylation; Injections, Subcutaneous; Liver Neoplasms; Lymphoma; Male; Methylation; Mice; Neoplasms, Experimental; Papilloma; Rats; Sarcoma; Skin Neoplasms; Stomach Neoplasms | 1973 |
A study of transfer RNA methylation.
Topics: Animals; Base Sequence; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Cytosol; Kinetics; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Polynucleotides; Rats; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Transfer RNA Aminoacylation; Valine | 1973 |
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine | 1973 |
Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
Topics: Adenine; Adenoviridae Infections; Animals; Cell-Free System; Chromatography, Paper; Cricetinae; Escherichia coli; Guanine; Methylation; Methyltransferases; Neoplasms, Experimental; RNA, Bacterial; RNA, Transfer; Tumor Virus Infections | 1972 |
Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma.
Topics: Amino Acids; Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Escherichia coli; Female; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Muscles; Mycoplasma; Neoplasms, Experimental; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Spleen | 1973 |
A study of transfer RNA methylation.
Topics: Animals; Base Sequence; Binding Sites; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Rats; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Valine | 1973 |
Transfer RNA base composition studies in Morris hepatomas and rat liver.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cytidine; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Transfer; Tritium; Uridine | 1974 |
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine | 1974 |
[Varying rate of destruction of alkylated molecules of RNA, protein and lipids in normal and neoplastic cells].
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Lipid Metabolism; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred C3H; Neoplasm Proteins; Neoplasms, Experimental; Nitrosourea Compounds; RNA, Neoplasm; Spleen | 1973 |
The formation of methylated bases in DNA by dimethylnitrosamine and its relation to differences in the formation of tumours in the livers of GR and C3HF mice.
Topics: Animals; Carbon Radioisotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Thin Layer; DNA; Fasting; Female; Half-Life; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred Strains; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Oxidoreductases, N-Demethylating; Species Specificity; Time Factors | 1974 |
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine | 1972 |
Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.
Topics: Adenosine; Carcinoma, Hepatocellular; Cell Fractionation; Cell Line; Cellulose; Chromatography; Cytidine; Guanosine; Liver Neoplasms; Methylation; Neoplasms, Experimental; Nucleosides; Oligonucleotides; Polyribosomes; RNA, Messenger; RNA, Neoplasm; Thymine Nucleotides | 1974 |
Base analysis of RNA by 3H postlabeling--a study of ribothymidine content and degree of base methylation of 4 S RNA.
Topics: Animals; Bacillus subtilis; Brain Chemistry; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Cytosol; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorescence; Isotope Labeling; Liver; Liver Neoplasms; Methylation; Mitochondria, Liver; Muscles; Neoplasms, Experimental; Organ Specificity; Rats; Ribonucleotides; RNA; RNA, Bacterial; RNA, Transfer; Tritium; Uridine | 1974 |
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases | 1974 |
[Ethylation of guanine-N-7 in the nucleic acids of rat embryos and liver by ethylnitrosourea].
Topics: Alkylation; Animals; Carbon Isotopes; Carcinogens; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; DNA; Embryo, Mammalian; Female; Guanine; Lethal Dose 50; Liver; Maternal-Fetal Exchange; Methylation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Pregnancy; Rats; RNA | 1971 |
Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.
Topics: Adenine; Animals; Brain; Brain Neoplasms; Carcinogens; DNA; DNA Repair; Female; Guanine; Kidney; Kidney Neoplasms; Liver; Methylation; Neoplasms, Experimental; Nitrosourea Compounds; Purines; Rats | 1974 |
[Dynamics of tissue methylation on the administration of symmetrical H3-dimethylhydrazine to rats].
Topics: Alkylation; Animals; Colon; DNA, Neoplasm; Duodenum; Hydrazines; Ileum; Injections, Subcutaneous; Intestinal Mucosa; Intestinal Neoplasms; Kidney; Liver; Male; Methylation; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Scintillation Counting; Spectrophotometry; Time Factors; Tritium | 1974 |
Modification of tumour growth with a defined glycoprotein antigen.
Topics: Adenocarcinoma; Animals; Antibody Formation; Antigens, Neoplasm; Erythrocytes; Fishes; Glycoproteins; Histocompatibility Antigens; Immunity; Immunization; Immunization Schedule; Immunosuppression Therapy; Mammary Neoplasms, Experimental; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Multiple Myeloma; Neoplasm Transplantation; Neoplasms, Experimental; Serum Albumin, Bovine; Sheep | 1973 |
Hepatocarcinogenicity of the trimethyl homologs of 4-dimethylaminazobenzene.
Topics: Animals; Carcinogens; Diet; Liver; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1972 |
Evidence for DNA repair synthesis and turnover in rat liver following ingestion of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; DNA; DNA Repair; DNA, Neoplasm; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Thymidine; Tritium | 1972 |
[Influence exerted by various estrogens on the process of liver cancerization in male rats poisoned by para-dimethylaminoazobenzene (DAB)].
Topics: Animals; Estrogens; Ethinyl Estradiol; Liver; Liver Glycogen; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; Oxidation-Reduction; p-Dimethylaminoazobenzene; Rats | 1972 |
Synthetic polynucleotides as model substrates for ribosomal RNA processing.
Topics: Adenosine Monophosphate; Ascitic Fluid; Carbon Radioisotopes; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cytosine Nucleotides; Exonucleases; Kinetics; Methylation; Neoplasms, Experimental; Polynucleotides; Ribonucleases; RNA, Ribosomal; Time Factors; Uracil Nucleotides | 1973 |
Effect of aminoacetonitrile on the metabolism of dimethylnitrosamine and methylation of RNA during liver carcinogenesis.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Guanine; Liver; Liver Neoplasms; Male; Methylamines; Methylation; Neoplasms, Experimental; Nitriles; Nitrosamines; Rats; RNA, Neoplasm; Time Factors | 1974 |
Rapid loss of 7-methylguanine from liver nucleic acids in mice during the initial stage of liver carcinogenesis induced by dimethylnitrosamine.
Topics: Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; DNA; Drinking Behavior; Guanine; Half-Life; Liver; Liver Neoplasms; Male; Methane; Methylation; Mice; Neoplasms, Experimental; Nitrosamines; Orotic Acid; RNA; Thymidine; Time Factors; Tritium | 1974 |
Studies on the role of stimulated epidermal DNA synthesis in the initiation of skin tumors in mice by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Acetone; Adenine; Animals; Autoradiography; Croton Oil; DNA; DNA Replication; Female; Guanine; Methylation; Mice; Neoplasms, Experimental; Nitrosoguanidines; Proteins; RNA; Skin; Skin Neoplasms; Thymidine; Tritium | 1974 |
Nucleic acid methylase activity in hamsters bearing tumors induced by adenovirus-12.
Topics: Adenoviridae; Animals; Carbon Isotopes; Cell-Free System; Cricetinae; DNA; Embryo, Mammalian; Escherichia coli; Kidney; Liver; Lung; Methylation; Muscles; Neoplasms, Experimental; Ribosomes; RNA, Bacterial; RNA, Transfer; Skin; Spleen; Transferases; Ultracentrifugation | 1968 |
Comparative transfer RNA methylase capacity in mouse ascites tumors and in their derived tumorigenic and nontumorigenic cell cultures.
Topics: Adenocarcinoma; Animals; Ascites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Escherichia coli; Female; Kidney; Liver; Lung; Lymphoma, Non-Hodgkin; Male; Methylation; Methylcholanthrene; Mice; Neoplasm Transplantation; Neoplasms, Experimental; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Transferases | 1971 |
The dimethylation of the tryptophan methyl ester and its possible biologic activity.
Topics: Animals; Biological Assay; Chromatography, Gas; Escherichia coli; Esters; Indoles; Magnetic Resonance Spectroscopy; Methylation; Mice; Microbial Sensitivity Tests; Neoplasms, Experimental; Spectrum Analysis; Tryptophan | 1971 |
Carcinogenic activity of analogues of p-dimethylaminoazobenzene. VII. Effect of two methyl groups in the pyridine series.
Topics: Animals; Carcinogens; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Stereoisomerism | 1968 |
Altered transfer RNA methylase patterns in Marek's disease tumors.
Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Cell-Free System; Chickens; Escherichia coli; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung; Methylation; Methyltransferases; Myocardium; Neoplasms; Neoplasms, Experimental; Nucleosides; Oncogenic Viruses; Poultry Diseases; RNA, Neoplasm; RNA, Transfer; Spleen; Transferases; Viruses, Unclassified | 1971 |
Further evidence of heterogeneity of ribosomal RNA in various rat tissues.
Topics: Animals; Cell Line; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Embryo, Mammalian; Isotope Labeling; Kidney; Liver; Methylation; Neoplasms, Experimental; Organ Specificity; Phosphorus Isotopes; Rats; Ribonucleases; Ribonucleotides; Ribosomes; RNA; RNA, Neoplasm; RNA, Ribosomal | 1972 |
Examination of the tumour growth promoting effect of -N-trimethyllysine. An autoradiographic study.
Topics: Animals; Ascites; Autoradiography; Female; Lymphoma; Lysine; Methylation; Mice; Mitosis; Neoplasms, Experimental; Thymidine; Time Factors; Tritium | 1971 |
Induction of malignant lymphomas by N,N'-dimethylnitrosourea in adult mice.
Topics: Animals; Carcinogens; Female; Lymphatic Metastasis; Lymphoma; Male; Methylation; Methylnitrosourea; Mice; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Thymus Neoplasms; Urea | 1971 |
Increased transfer ribonucleic acid methylase activity in tumours induced in the mouse colon by the administration of 1,2-dimethylhydrazine.
Topics: Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Fossil Fuels; Hydrazines; Male; Methylation; Methyltransferases; Mice; Neoplasms, Experimental; Proteins; RNA, Transfer | 1971 |
Carcinogenic and adrenocorticolytic derivatives of benz(a) anthracene.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Isomerism; Male; Methylation; Neoplasms, Experimental; Rats; Sarcoma; Structure-Activity Relationship; Time Factors | 1971 |
Cellular injury and carcinogenesis. The effect of a protein-free high-carbohydrate diet on the metabolism of dimethylnitrosamine in the rat.
Topics: Animals; Dietary Carbohydrates; Dietary Proteins; DNA; Guanine; Kidney; Kidney Neoplasms; Liver; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; RNA; Time Factors | 1971 |
Transfer RNA-methylating enzymes in mammary carcinoma cells.
Topics: Animals; Carbon Isotopes; Deoxyribonucleases; Electrophoresis; Mammary Neoplasms, Experimental; Methylation; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Ribonucleases; RNA, Neoplasm; RNA, Transfer; Transferases | 1970 |
Comparison of methyl-labeled tRNA in a neoplastic cell line with a paired non-neoplastic control.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chemistry Techniques, Analytical; Chromatography; Culture Techniques; Embryo, Mammalian; Methionine; Methylation; Mice; Neoplasms, Experimental; RNA, Transfer; Tritium | 1970 |
Studies on lung tumours. I. Methylation of deoxyribonucleic acid and tumour formation following administration of dimethylnitrosamine to mice.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; DNA, Neoplasm; Guanine Nucleotides; Kidney; Kinetics; Liver; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosamines; Species Specificity; Spleen; Time Factors | 1970 |
Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine.
Topics: Adenocarcinoma; Animals; Chromatography, Paper; Electrophoresis; Glucosyltransferases; L Cells; Leukemia L1210; Liver Neoplasms; Mercaptopurine; Methylation; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides; Purines; Sulfur Isotopes | 1971 |
Enzymic modification of chromosomal macromolecules. I. DNA and protein methylation in mouse tumour cell chromatin.
Topics: Amino Acids; Animals; Arginine; Ascitic Fluid; Catalysis; Cell Nucleus; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography; Chromatography, Paper; Chromosomes; Colorimetry; Cytosine; Deoxyribonucleases; DNA, Neoplasm; Drug Stability; Electrophoresis; Histidine; Histones; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Methylation; Methyltransferases; Mice; Neoplasm Proteins; Neoplasms, Experimental; S-Adenosylmethionine; Temperature; Time Factors; Transferases; Tritium | 1971 |
Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.
Topics: Adenine; Adenoma; Animals; Bone Marrow; Carbon Isotopes; DNA, Neoplasm; Guanine; Kidney; Liver; Lung; Lung Neoplasms; Lymphoma; Methylation; Mice; Neoplasms, Experimental; Nitroso Compounds; Spleen; Thymus Gland; Thymus Neoplasms; Urea | 1971 |
In vitro transfer RNA methylation in paired neoplastic and nonneoplastic cell cultures.
Topics: Animals; Carbon Isotopes; Cell Differentiation; Cell Transformation, Neoplastic; Cell-Free System; Chromatography; Culture Techniques; Methylation; Mice; Neoplasms, Experimental; Nucleic Acids; Nucleotides; RNA, Neoplasm; RNA, Transfer; Transferases; Tritium | 1971 |
The carcinogenicity of the o-methoxy derivatives of N-2-fluorenylacetamide and of related compounds in the rat.
Topics: Adenocarcinoma; Animals; Biotransformation; Carbon Dioxide; Carbon Isotopes; Carcinogens; Chromatography, Paper; Chromatography, Thin Layer; Female; Fluorenes; Intestinal Neoplasms; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Methylation; Neoplasms, Experimental; Rats; Spectrum Analysis; Ultraviolet Rays | 1968 |
The effect of halogenated nucleosides on the sensitivity of a mouse lymphoma P388F to x-rays and methyl methanesulphonate.
Topics: Alkylating Agents; Deoxyuridine; Lymphoma; Methane; Methylation; Neoplasms, Experimental; Radiation-Sensitizing Agents; Sulfonic Acids | 1968 |
[In vivo methylation of rat liver RNA and under the influence of diethylnitrosamine].
Topics: Animals; Carbon Isotopes; Carcinogens; Centrifugation, Zonal; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nitrosamines; Orotic Acid; Rats; Ribosomes; RNA; Tritium | 1968 |
Theory of tumour initiation by chemical carcinogens: dependence of activity on structure of ultimate carcinogen.
Topics: Amines; Azo Compounds; Carcinogens; Chemical Phenomena; Chemistry; DNA; Hydrocarbons; Methylation; Neoplasms, Experimental; Structure-Activity Relationship | 1968 |
Chromosomal ribonucleic acid of rat ascites cells.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Chromosomes; Cytoplasm; DNA, Neoplasm; Histones; Male; Methylation; Neoplasms, Experimental; Nucleic Acid Denaturation; Nucleotides; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA, Neoplasm; RNA, Transfer; Spectrum Analysis; Thymidine; Tritium | 1969 |