isomethyleugenol has been researched along with Experimental Hepatoma in 115 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 69 (60.00) | 18.7374 |
1990's | 41 (35.65) | 18.2507 |
2000's | 3 (2.61) | 29.6817 |
2010's | 2 (1.74) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cheng, EH; Dong, Y; Hsieh, JJ; Liu, H; Sasagawa, S; Takeda, S; Trainor, PA | 1 |
Beland, FA; Pogribny, IP; Ross, SA; Tryndyak, VP | 1 |
Devaraj, SN; Halagowder, D; Khan, MS | 1 |
Kim, S; Kim, YS; Lou, MF; Paik, MK; Paik, WK | 1 |
Brosnan, JT; Brosnan, ME; Noga, AA; Stead, LM; Vance, DE; Zhao, Y | 1 |
Becker, FF; Lapeyre, JN; Maizel, AL | 1 |
Andrews, GK; Dziadek, M; Tamaoki, T | 1 |
Gomez-Garcia, M; Sala, M; Sala-Trepat, JM; Vedel, M | 1 |
Lu, LJ; Randerath, E; Randerath, K | 1 |
Becker, FF; Iyer, B; Kuo, MT; Lapeyre, JN; Wu, JR | 1 |
Delers, A; Saggioro, D; Szpirer, C; Szpirer, J | 1 |
Lan, NC | 1 |
Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C | 1 |
Hoshino, J; Kröger, H; Seifert, R | 1 |
Becker, FF; Lapeyre, JN; Walker, MS | 1 |
Weinhouse, S | 1 |
Farber, E; Ghoshal, AK | 1 |
Ott, MO; Sperling, L; Weiss, MC | 1 |
Agrawal, HP; Randerath, E; Randerath, K | 1 |
Katznelson, R; Kulka, RG | 2 |
Fuke, M; Sardana, MK | 1 |
Leboy, PS; Salas, CE; Uschmann, BD | 1 |
Cassio, D; Levilliers, J; Ott, MO; Sala-Trepat, J; Sperling, L; Weiss, MC | 1 |
Busch, H; Lischwe, MA; Roberts, KD; Yeoman, LC | 1 |
Agrawal, HP; Gopalakrishnan, AS; Gupta, RC; Randerath, E; Randerath, K | 1 |
Hirabayashi, Y; Li, SC; Li, YT; Matsumoto, M; Pascher, I; Samuelsson, B; Taki, T | 1 |
Aresta, A; Farber, E; Kanduc, D | 1 |
Benvenuto, G; Bruni, CB; Chiariotti, L; Colantuoni, V; Rossi, E; Salvatore, P; Zarrilli, R | 1 |
Christman, JK | 1 |
Hanami, T; Mizuno, Y; Muramatsu, M; Ohsumi, T; Okazaki, Y; Okuizumi, H; Sasaki, N; Shibata, K; Takahara, T; Ueda, M | 1 |
Oshima, H; Simons, SS; Szapary, D | 1 |
Ayté, J; Gil-Gómez, G; Hegardt, FG | 1 |
Bourrillon, R; Goulut-Chassaing, C | 1 |
Rogers, AE | 1 |
Lyn-Cook, BD; Ringer, DP; Yerokun, T | 1 |
Counts, JL; Goodman, JI | 3 |
Poirier, LA | 1 |
Bennati, S; Daino, L; Feo, F; Gaspa, L; Pascale, RM; Pinna, G; Seddaiu, MA; Simile, MM; Vinci, MA | 1 |
Kurishita, A; Miyamura, Y; Niwa, O; Ohtsu, H; Ono, T; Sado, T; Watanabe, H | 1 |
Huber, BE; Richards, CA | 1 |
Carr, LG; Edenberg, HJ; Lin, Z | 1 |
Asakura, H; Endo, Y; Kanda, H; Kitagawa, T; Kominami, R; Nomura, K; Tsunashima, K | 1 |
Counts, JL; Downing, JC; Goodman, JL; Harbison, ML; McClain, RM; Sarmiento, JI | 1 |
Floreani, M; Geroni, C; Napoli, E; Quintieri, L; Rosato, A; Sola, F; Zanovello, P | 1 |
Kibert, L; Ove, P; Short, J; Wedmore, R; Zemel, R | 1 |
Bayev, AA; Gambaryan, AS; Morozov, IA; Venkstern, TV | 1 |
Coward, J; Kaehler, M; Rottman, F | 1 |
Breland, JC; Carter, GL; Cory, JG | 1 |
Kaput, J; Sneider, TW | 1 |
D'Agostino, F; Kanduc, D | 1 |
Whitlock, JP; Wu, L | 1 |
Deeg, MA; Murray, NR; Rosenberry, TL | 1 |
Cronin, GM; Lyn-Cook, BD; Poirier, LA; Zapisek, WF | 1 |
Coni, P; Hsu, S; Pang, J; Pichiri-Coni, G; Rajalakshmi, S; Rao, PM; Sarma, DS | 1 |
Nguyen, T; Pickett, CB | 1 |
Goodman, JI; Vorce, RL | 3 |
Baik, JH; Giuili, G; Griffiths, S; Guellaen, G; Manson, M; Siegrist, S | 1 |
Grange, T; Pictet, R; Rigaud, G; Roux, J | 1 |
Zhao, QZ | 1 |
Miller, MS | 1 |
Hancock, RL | 1 |
Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N | 1 |
Barrass, NC; Evans, JG; Phillimore, HE; Rumsby, PC | 1 |
Ikeda, Y; Jain, S; Jain, SK; Matsunaga, M; Sugiyama, T; Taniguchi, N | 1 |
Bax, H; Scherer, E; van Benthem, J | 1 |
Akedo, H; Ashida, Y; Inoue, H; Isoai, A; Kido, J; Kumagai, H; Shinkai, K | 1 |
Hernandez, L; Hughes, SH; Lijinsky, W; Petropoulos, CJ | 1 |
Archer, MC; Chin, W; Cooper, DP; Dai, WD; Lee, V; O'Connor, PJ | 1 |
Cameron, R; Ding, VD; Pickett, CB | 1 |
Chung, FL; Hecht, SS; Morse, MA | 1 |
Aksamit, RR; Datko, AH; Mudd, SH | 1 |
Boulter, J; Longley, MA; Sell, S | 1 |
Fausto, N; Panzica, M; Petropoulos, CJ; Yaswen, P | 1 |
Gonzalez, FJ; Nebert, DW; Peterson, TC | 1 |
Hutt, S; Locker, J; Lombardi, B | 1 |
Bélanger, L; Chevrette, M; Guertin, M; LaRue, H; Turcotte, B | 1 |
Chiu, JF; Cook, JR; Sakuma, K; Smith, CL | 1 |
Nahon, JL; Sala-Trepat, JM; Tratner, I; Venetianer, A | 1 |
Crawford, N; Locker, J; Schulz, WA | 1 |
Bernuau, D; Feldmann, G; Gal, A; Legrès, L; Nahon, JL; Poiret, M; Poliard, A; Presse, F; Sala-Trepat, JM; Tratner, I | 1 |
Daino, L; Feo, F; Garcea, R; Pascale, R; Puddu, M; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM | 1 |
Chiu, JF; Nordloh, PW; Smith, CL | 1 |
Shen, ES; Whitlock, JP | 1 |
Akedo, H; Horai, T; Inoue, H; Mukai, M; Nishikawa, S; Ohigashi, H; Shinkai, K; Takeda, Y | 1 |
Denda, A; Rajalakshmi, S; Rao, PM; Sarma, DS | 1 |
He, ZX; Wu, GL; Xue, JY | 1 |
Antony, A; Rajalakshmi, S; Rao, PM; Sarma, DS | 1 |
Chalkley, R; Granner, DK; Ip, YT | 1 |
Bock, KW; Münzel, P | 1 |
Barton, DE; Francke, U | 1 |
Miller, MS; Wogan, GN | 1 |
Koenderman, AH; Koppen, PL; Van den Eijnden, DH | 1 |
Koenderman, AH; Schiphorst, WE; van den Eijnden, DH | 1 |
Chasin, LA; Orlofsky, A | 1 |
Daimon, M; Ishikawa, K; Tsutsumi, K | 1 |
Bailey, G; Davie, JR; Delcuve, GP; Moirier, R; Nickel, BE | 1 |
Farber, E; Ghoshal, A; Kanduc, D; Quagliariello, E | 1 |
Bhave, MR; Poirier, LA; Wilson, MJ | 1 |
Shank, RC | 1 |
Goldsworthy, TL; Hanigan, MH; Pitot, HC | 1 |
Jeltsch, W; Kleihues, P; Lijinsky, W; Schmerold, I; von Hofe, E | 1 |
Kammerer, RC; Kloc, K; Lampe, MA; Schmitz, DA | 1 |
Locker, J; Lombardi, B; Reddy, TV | 1 |
Bosan, WS; Gaworski, CL; MacEwen, JD; Newberne, PM; Shank, RC | 1 |
Cassio, D; Sellem, CH; Weiss, MC | 1 |
Becker, R; Hall, J; Likhachev, A; Lu, SH; Montesano, R; Umbenhauer, D; Wild, CP | 1 |
Ando, S; Hirabayashi, Y; Ishikawa, H; Kon, K; Matsumoto, M; Taki, T; Tanaka, Y | 1 |
Archer, MC; Silinskas, KC; Zucker, PF | 1 |
Fringes, B; Kleihues, P; Schmerold, I; Volk, B; Wiestler, OD | 1 |
Cassio, D; Levilliers, J; Ott, MO; Sellem, CH; Sperling, L; Weiss, MC | 1 |
9 review(s) available for isomethyleugenol and Experimental Hepatoma
Article | Year |
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Differential expression of microRNAs during hepatocarcinogenesis induced by methyl deficiency in rats.
Topics: Animals; Diet; Down-Regulation; Gene Expression; Genes, Tumor Suppressor; Liver Neoplasms, Experimental; Methylation; MicroRNAs; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Isozyme alterations, gene regulation and the neoplastic transformation.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fetal Proteins; Gene Expression Regulation; Glycolysis; Hormones; Isoenzymes; Liver Neoplasms, Experimental; Methylation; Oncogenes; Rats | 1983 |
Dietary effects on DNA methylation: do they account for the hepatocarcinogenic properties of lipotrope deficient diets?
Topics: Animals; Diet; DNA; Humans; Lipotropic Agents; Liver; Liver Neoplasms, Experimental; Methylation; Mutation | 1995 |
Methyl donors in the diet and responses to chemical carcinogens.
Topics: Animals; Carcinogens; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms, Experimental; Methionine; Methylation; Neoplasms | 1995 |
Methyl group deficiency in hepatocarcinogenesis.
Topics: Animals; Choline Deficiency; Diet; Folic Acid Deficiency; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine; Methylation; Oncogenes; S-Adenosylmethionine | 1994 |
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: is DNA methylation involved?
Topics: Animals; Anticarcinogenic Agents; DNA; Gene Expression; Genes, myc; Genes, ras; Liver Neoplasms, Experimental; Methylation; Rats; S-Adenosylmethionine | 1993 |
Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion.
Topics: Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; DNA; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Methylation; Mice | 1995 |
Models of hepatocarcinogenesis in the rat--contrasts and comparisons.
Topics: Animals; Animals, Newborn; Carcinogens; Diet; Disease Models, Animal; Female; Hepatectomy; Liver Neoplasms, Experimental; Methylation; Pregnancy; Rats | 1986 |
Repair of DNA alkylation adducts in mammalian cells.
Topics: Alkylating Agents; Alkylation; Animals; Carcinogens; Cricetinae; DNA; DNA Repair; Humans; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1985 |
106 other study(ies) available for isomethyleugenol and Experimental Hepatoma
Article | Year |
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HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Embryo, Mammalian; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocyte Growth Factor; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms, Experimental; Male; Matrix Metalloproteinases, Secreted; Methylation; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Invasiveness; Neoplasm Transplantation; Promoter Regions, Genetic; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins c-met; Signal Transduction; Transcriptional Activation | 2013 |
Methylated chrysin, a dimethoxy flavone, partially suppresses the development of liver preneoplastic lesions induced by N-nitrosodiethylamine in rats.
Topics: Animals; Base Sequence; Carcinogens; Cell Cycle Proteins; Diethylnitrosamine; DNA Primers; DNA Repair; Flavonoids; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms, Experimental; Methylation; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Methylation of nuclear proteins of Novikoff hepatoma.
Topics: Animals; Cell Nucleus; Histones; Kinetics; Liver; Liver Neoplasms, Experimental; Lysine; Male; Methylation; Nuclear Proteins; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1980 |
Plasma homocysteine is regulated by phospholipid methylation.
Topics: Animals; Hepatocytes; Homocysteine; Liver Neoplasms, Experimental; Male; Methylation; Methyltransferases; Mice; Mice, Knockout; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Rats; Rats, Mutant Strains; Recombinant Proteins; Reference Values; Transfection | 2003 |
DNA methylation of liver and HTC cells during corticosteroid induction.
Topics: Adrenalectomy; Animals; DNA; DNA (Cytosine-5-)-Methyltransferases; Enzyme Induction; Hydrocortisone; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Tyrosine Transaminase | 1980 |
Expression and methylation of the mouse alpha-fetoprotein gene in embryonic, adult, and neoplastic tissues.
Topics: alpha-Fetoproteins; Animals; DNA; DNA Restriction Enzymes; Female; Genes; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Pregnancy; RNA, Messenger; Transcription, Genetic; Yolk Sac | 1982 |
Changes in methylation pattern of albumin and alpha-fetoprotein genes in developing rat liver and neoplasia.
Topics: Aging; alpha-Fetoproteins; Animals; Cell Line; DNA; DNA Restriction Enzymes; Female; Genes; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Pregnancy; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Serum Albumin | 1983 |
DNA hypomethylation in Morris hepatomas.
Topics: 5-Methylcytosine; Animals; Cytosine; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Liver Neoplasms, Experimental; Methylation; Neoplasm Transplantation; Rats; Rats, Inbred ACI | 1983 |
Methylation of the alpha-fetoprotein gene in productive and nonproductive rat hepatocellular carcinomas.
Topics: alpha-Fetoproteins; Animals; Cell Nucleus; DNA Restriction Enzymes; DNA, Neoplasm; Genes; Liver Neoplasms, Experimental; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Species Specificity | 1984 |
Spontaneous and 5-azacytidine-induced reexpression of ornithine carbamoyl transferase in hepatoma cells.
Topics: Animals; Azacitidine; Cell Differentiation; Cell Line; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Methylation; Ornithine Carbamoyltransferase; Rats | 1984 |
The effects of 5-azacytidine on the expression of the rat growth hormone gene. Methylation modulates but does not control growth hormone gene activity.
Topics: Adrenocorticotropic Hormone; Animals; Azacitidine; Cell Line; DNA; Gene Expression Regulation; Growth Hormone; Liver Neoplasms, Experimental; Methylation; Mice; Nucleic Acid Precursors; Pituitary Neoplasms; Prolactin; Rats; RNA Precursors; RNA, Messenger | 1984 |
The tumorigenicity of 5-azacytidine in the male Fischer rat.
Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms | 1984 |
Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes.
Topics: Aging; Animals; Brain; Carcinoma, Ehrlich Tumor; Cell Line; Female; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains; Sarcoma 180; Sarcoma, Yoshida; Tissue Distribution | 1984 |
DNA methylation and methylase levels in normal and malignant mouse hepatic tissues.
Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Rodent Diseases | 1981 |
The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens.
Topics: Animals; Choline Deficiency; DNA; Liver Neoplasms, Experimental; Male; Methionine; Methylation; Phenobarbital; Rats; Rats, Inbred F344 | 1984 |
Albumin extinction without methylation of its gene.
Topics: Albumins; Animals; Gene Expression Regulation; Genes; Hybrid Cells; Kinetics; Liver Neoplasms, Experimental; Methylation; Rats | 1984 |
tRNA alterations in cancer.
Topics: Animals; Base Sequence; Female; Humans; Liver; Liver Neoplasms, Experimental; Methylation; Neoplasms; Nucleic Acid Conformation; Placenta; Pregnancy; Rats; Ribonucleosides; RNA, Neoplasm; RNA, Transfer | 1983 |
Degradation of microinjected methylated and unmethylated proteins in hepatoma tissue culture cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Erythrocyte Membrane; Half-Life; Humans; Liver Neoplasms, Experimental; Methylation; Microinjections; Muramidase; Proteins; Serum Albumin, Bovine | 1983 |
A rapid procedure to determine the content of 2'-O-methylation in RNA by homochromatography.
Topics: Animals; Cell Line; Chickens; Chromatography, Paper; Electrophoresis, Paper; Liver Neoplasms, Experimental; Marek Disease; Methylation; Nucleotides; Rats; RNA, Ribosomal; Saccharomyces cerevisiae | 1980 |
Methyl-accepting RNA in 13762 mammary adenocarcinoma correlated with low adenine methyltransferase levels.
Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Female; Liver; Liver Neoplasms, Experimental; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Rats; Rats, Inbred F344; RNA, Transfer; tRNA Methyltransferases | 1982 |
Undermethylation at the 5' end of the albumin gene is necessary but not sufficient for albumin production by rat hepatoma cells in culture.
Topics: Albumins; Animals; Cell Differentiation; Cell Line; Chromosome Mapping; Gene Expression Regulation; Genes; Hybrid Cells; Liver; Liver Neoplasms, Experimental; Methylation; Operon; Rats | 1982 |
Nucleolar specific acidic phosphoprotein C23 is highly methylated.
Topics: Amino Acids; Animals; Arginine; Cell Nucleolus; Liver Neoplasms, Experimental; Methylation; Molecular Weight; Phosphoproteins; Rats | 1982 |
Lack of a specific ribose methylation at guanosine 17 in Morris hepatoma 5123D tRNASer1IGA.
Topics: Animals; Anticodon; Base Sequence; Chromatography, Thin Layer; Guanosine; Immunoglobulin A; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; Rats; RNA, Transfer | 1981 |
Further characterization of the structure of GM1b ganglioside from rat ascites hepatoma.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; G(M1) Ganglioside; Gangliosides; Gas Chromatography-Mass Spectrometry; Liver Neoplasms, Experimental; Methylation; Rats | 1981 |
Hypermethylation of replicating hepatic DNA following N-methyl-N-nitrosourea administration.
Topics: Animals; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Damage; DNA Replication; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Methylation; Methylnitrosourea; Mitogens; Rats; Rats, Wistar; Sensitivity and Specificity; Tritium | 1994 |
Activation of the galectin-1 (L-14-I) gene from nonexpressing differentiated cells by fusion with undifferentiated and tumorigenic cells.
Topics: Alleles; Animals; Azacitidine; Base Sequence; Cell Differentiation; Cell Fusion; Cells, Cultured; Galectin 1; Gene Expression Regulation, Neoplastic; Genes, Dominant; Hemagglutinins; Humans; Liver; Liver Neoplasms, Experimental; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Osteosarcoma; Rats; Tumor Cells, Cultured | 1994 |
Loss of heterozygosity in chromosomes 1, 5, 7 and 13 in mouse hepatoma detected by systematic genome-wide scanning using RLGS genetic map.
Topics: Animals; Blotting, Southern; Chromosome Mapping; Crosses, Genetic; DNA, Neoplasm; Heterozygote; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Transgenic; Polymorphism, Restriction Fragment Length | 1995 |
The factor binding to the glucocorticoid modulatory element of the tyrosine aminotransferase gene is a novel and ubiquitous heteromeric complex.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Nucleus; Chromatography, Affinity; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation, Enzymologic; Glucocorticoids; HeLa Cells; Humans; Kinetics; L Cells; Liver Neoplasms, Experimental; Macromolecular Substances; Methylation; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Biosynthesis; Rats; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine Transaminase | 1995 |
Methylation of the regulatory region of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene leads to its transcriptional inactivation.
Topics: Animals; Animals, Newborn; Azacitidine; DNA; Exons; Fetus; Gene Expression; Hydroxymethylglutaryl-CoA Synthase; Kidney; Liver Neoplasms, Experimental; Male; Methylation; Mitochondria, Liver; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Restriction Mapping; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Structural differences between complex-type Asn-linked glycan chains of glycoproteins in rat hepatocytes and Zajdela hepatoma cells.
Topics: Animals; Carbohydrate Sequence; Chromatography, Affinity; Glucosidases; Glycopeptides; Lectins; Liver; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Male; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Rats; Rats, Sprague-Dawley | 1995 |
Hypomethylation of the rat aryl sulfotransferase IV gene and amplification of a DNA sequence during multistage 2-acetylaminofluorene hepatocarcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Arylsulfotransferase; Cricetinae; DNA, Complementary; Gene Amplification; Liver; Liver Neoplasms, Experimental; Methylation; Polymorphism, Restriction Fragment Length; Rats; RNA, Messenger | 1994 |
Hypomethylation of DNA: a possible nongenotoxic mechanism underlying the role of cell proliferation in carcinogenesis.
Topics: 5-Methylcytosine; Animals; Cell Division; Cytosine; DNA; Female; Liver Neoplasms, Experimental; Male; Methylation; Mice; Neoplasms; Proto-Oncogenes | 1993 |
Comparative analysis of the methylation status of the 5' flanking region of Ha-ras in B6C3F1, C3H/He and C57BL/6 mouse liver.
Topics: 5-Methylcytosine; Animals; Base Sequence; Blotting, Southern; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Male; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Oligonucleotide Probes; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Analysis, DNA | 1993 |
Comparison of the age- and tumor-associated changes in the c-myc gene methylation in mouse liver.
Topics: Aging; Animals; DNA; DNA, Neoplasm; Genes, myc; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL | 1993 |
Generation of a transgenic model for retrovirus-mediated gene therapy for hepatocellular carcinoma is thwarted by the lack of transgene expression.
Topics: Albumins; Animals; Chimera; Crosses, Genetic; Female; Gene Expression; Genetic Therapy; Genetic Vectors; Herpesvirus 3, Human; Liver Neoplasms, Experimental; Male; Methylation; Mice; Mice, Inbred DBA; Mice, Transgenic; Models, Biological; Pedigree; Regulatory Sequences, Nucleic Acid; Retroviridae; Thymidine Kinase | 1993 |
A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1.
Topics: Alcohol Dehydrogenase; Analysis of Variance; Animals; Base Sequence; Binding Sites; Cell Nucleus; Deoxyribonuclease I; DNA; DNA Probes; DNA-Binding Proteins; Humans; Liver; Liver Neoplasms, Experimental; Luciferases; Methylation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Nucleic Acid; Transfection; Tumor Cells, Cultured | 1993 |
A novel clonality assay for the mouse: application to hepatocellular carcinomas induced with diethylnitrosamine.
Topics: Animals; Base Sequence; Carcinogens; Clone Cells; Diethylnitrosamine; DNA Primers; DNA, Neoplasm; Dosage Compensation, Genetic; Liver Neoplasms; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred Strains; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Sequence Deletion | 1996 |
Cell proliferation and global methylation status changes in mouse liver after phenobarbital and/or choline-devoid, methionine-deficient diet administration.
Topics: Animals; Carcinogens; Cell Division; Choline Deficiency; Cocarcinogenesis; Diet; DNA; Liver; Liver Neoplasms, Experimental; Male; Methionine; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phenobarbital | 1996 |
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Doxorubicin; Erythromycin; Female; Leukemia, Experimental; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases, N-Demethylating; Pregnenolone Carbonitrile; Protein Synthesis Inhibitors; Time Factors; Troleandomycin; Tumor Cells, Cultured | 2000 |
Chromatin protein methylation in proliferating liver and hepatoma cells.
Topics: Animals; Cell Division; Chromosomal Proteins, Non-Histone; Female; Histones; Hydrogen-Ion Concentration; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Methylation; Rats | 1979 |
The mechanism of action of tRNA methylases studied with immobilized tRNAs.
Topics: Animals; Kidney Neoplasms; Kinetics; Liver Neoplasms, Experimental; Methylation; Neoplasms, Experimental; Rats; RNA, Transfer; Substrate Specificity; tRNA Methyltransferases | 1979 |
Cytoplasmic location of undermethylated messenger RNA in Novikoff cells.
Topics: Animals; Cell Line; Liver Neoplasms, Experimental; Methylation; Poly A; Polyribosomes; Rats; Ribosomes; RNA, Messenger | 1979 |
Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells.
Topics: Animals; Cell Line; Drug Resistance; Fluorouracil; Inosine; Liver Neoplasms, Experimental; Methylation; Rats; Ribonucleotides; RNA, Neoplasm; Thymidine; Thymidylate Synthase | 1979 |
Methylation of somatic vs germ cell DNAs analyzed by restriction endonuclease digestions.
Topics: Animals; Base Sequence; Cattle; DNA; DNA Restriction Enzymes; Kidney; Liver; Liver Neoplasms, Experimental; Male; Methylation; Nucleic Acid Denaturation; Organ Specificity; Rats; Spermatozoa; Thymus Gland | 1979 |
[Specificity of the reaction of chemical methylation of tRNA by means of methylsulfate. II. Chemical methylation of normal, methyl-deficient and tumor tRNA with dimethylsulfate].
Topics: Animals; Liver Neoplasms; Liver Neoplasms, Experimental; Methylation; Rats; RNA, Neoplasm; RNA, Transfer; Sulfates | 1978 |
Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo.
Topics: Animals; Base Sequence; Benzopyrene Hydroxylase; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; In Vitro Techniques; Liver Neoplasms, Experimental; Methylation; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Protein Binding; Receptors, Aryl Hydrocarbon; Receptors, Drug; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Identification of glycoinositol phospholipids in rat liver by reductive radiomethylation of amines but not in H4IIE hepatoma cells or isolated hepatocytes by biosynthetic labeling with glucosamine.
Topics: Amines; Animals; Cell Membrane; Cells, Cultured; Chromatography, Thin Layer; Glucosamine; Hydrolysis; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methylation; Oxidation-Reduction; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Tumor Cells, Cultured | 1992 |
The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Diet; Diethylnitrosamine; DNA Probes; DNA, Neoplasm; Liver Neoplasms, Experimental; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344 | 1992 |
Hypomethylation of beta-hydroxy-beta-methyl-glutaryl coenzyme A reductase gene and its expression during hepatocarcinogenesis in the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Base Sequence; Dimethylhydrazines; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Liver Neoplasms, Experimental; Male; Methylation; Mevalonic Acid; Molecular Sequence Data; Rats; Rats, Inbred F344 | 1992 |
Regulation of rat glutathione S-transferase Ya subunit gene expression. DNA-protein interaction at the antioxidant responsive element.
Topics: Animals; Base Sequence; DNA Fingerprinting; DNA-Binding Proteins; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Liver Neoplasms, Experimental; Methylation; Molecular Sequence Data; Nucleotides; Rats; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors.
Topics: Animals; Carcinoma, Hepatocellular; Chloroform; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylation; Mice; Phenobarbital; Restriction Mapping; Rodent Diseases | 1991 |
DNA methylation patterns of the rat gamma-glutamyl transpeptidase gene in embryonic, adult and neoplastic liver.
Topics: Animals; Blotting, Southern; DNA; Fetus; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Rats, Inbred F344 | 1991 |
In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Deoxyribonuclease I; DNA, Neoplasm; Genes; Liver; Liver Neoplasms, Experimental; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Receptors, Glucocorticoid; Transcription, Genetic; Tyrosine Transaminase | 1991 |
[The expression of alpha 1-inhibitor 3 gene and some changes of its structure in rat hepatomas].
Topics: Acute-Phase Proteins; Animals; Diethylnitrosamine; DNA Transposable Elements; Female; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Male; Methylation; Phenobarbital; Polymorphism, Restriction Fragment Length; Protease Inhibitors; Rats; Rats, Inbred Strains | 1991 |
Differential effects of N-methyl-N'-nitro-N-nitrosoguanidine on constitutive and hormone-inducible gene expression in rat hepatoma cells.
Topics: Animals; Cadmium; Deoxyribonuclease EcoRI; Deoxyribonuclease HindIII; Dexamethasone; DNA; Gene Expression; Liver Neoplasms, Experimental; Metallothionein; Methylation; Methylnitronitrosoguanidine; Nucleic Acid Hybridization; Rats; Receptors, Glucocorticoid; RNA; Tubulin; Tumor Cells, Cultured; Tyrosine Transaminase | 1990 |
[Theoretical mechanism of ethionine hepatocarcinogenesis].
Topics: alpha-Fetoproteins; Animals; Cell Differentiation; DNA; Ethionine; Gene Expression Regulation, Neoplastic; Heterochromatin; Liver Neoplasms; Liver Neoplasms, Experimental; Methylation; Rats | 1990 |
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains | 1991 |
Analysis of the Ha-ras oncogene in C3H/He mouse liver tumours derived spontaneously or induced with diethylnitrosamine or phenobarbitone.
Topics: Animals; Base Sequence; Blotting, Southern; Codon; Diethylnitrosamine; DNA; Gene Expression; Genes, ras; Immunoblotting; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C3H; Molecular Sequence Data; Mutation; Phenobarbital; RNA, Neoplasm | 1991 |
Enhancing effect of a choline-deficient diet on alterations of hepatic drug-metabolizing enzymes in hepatitis- and hepatoma-predisposed rats (LEC rats).
Topics: Animals; Blotting, Northern; Blotting, Western; Choline Deficiency; Cytochrome P-450 Enzyme System; Glutathione Transferase; Hepatitis, Animal; Liver Neoplasms, Experimental; Male; Methylation; Rats; Rats, Mutant Strains | 1991 |
Immunocytochemical analysis of carcinogen-DNA adducts in normal and preneoplastic tissues.
Topics: Animals; Biotransformation; Carcinogens; DNA; DNA, Neoplasm; Guanine; Immunohistochemistry; Liver Neoplasms, Experimental; Methylation; Nasal Cavity; Precancerous Conditions; Rats | 1991 |
Effects of methylthiodeoxyadenosine and its analogs on in vitro invasion of rat ascites hepatoma cells and methylation of their phospholipids.
Topics: Animals; Cell Division; Cell Membrane; Deoxyadenosines; In Vitro Techniques; Liver Neoplasms, Experimental; Membrane Fluidity; Membrane Lipids; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Phospholipids; Thionucleosides; Thionucleotides; Tumor Cells, Cultured | 1991 |
DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture.
Topics: Animals; Deoxycytidine; DNA; Gene Expression; Liver; Liver Neoplasms, Experimental; Male; Methapyrilene; Methylation; Oncogenes; Rats; Rats, Inbred F344; Tumor Cells, Cultured | 1991 |
DNA methylation in specific cells of rat liver by N-nitrosodimethylamine and N-nitrosomethylbenzylamine.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Species Specificity | 1991 |
Alterations in the methylation status of ras oncogenes in B6C3F1 mouse liver tumors.
Topics: Animals; Disease Susceptibility; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins p21(ras) | 1990 |
Regulation of microsomal, xenobiotic epoxide hydrolase messenger RNA in persistent hepatocyte nodules and hepatomas induced by chemical carcinogens.
Topics: Animals; DNA; Drug Resistance; Epoxide Hydrolases; Gene Expression Regulation, Enzymologic; Liver Neoplasms, Experimental; Male; Methylation; Microsomes, Liver; Precancerous Conditions; Rats; Rats, Inbred Strains; RNA, Messenger | 1990 |
Inhibition of tobacco-specific nitrosamine 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumors and DNA methylation in F344 rats and A/J mice by phenethyl isothiocyanate.
Topics: Animals; DNA; Isothiocyanates; Liver Neoplasms, Experimental; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Nose Neoplasms; Organ Specificity; Rats; Rats, Inbred F344; Thiocyanates | 1990 |
Phosphatidylcholine synthesis in the rat: the substrate for methylation and regulation by choline.
Topics: Animals; Choline; Ethanolamines; Liver; Liver Neoplasms, Experimental; Male; Methionine; Methylation; Phosphatidylcholines; Rats; Rats, Inbred Strains; Tritium; Tumor Cells, Cultured | 1990 |
Lack of correlation of methylation and alphafetoprotein and albumin gene expression during liver growth, in hepatocellular carcinomas, and during hepatocarcinogenesis.
Topics: Albumins; alpha-Fetoproteins; Animals; DNA; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Rats, Inbred ACI; Rats, Inbred F344; Rats, Inbred Strains; RNA, Messenger | 1985 |
Methylation of the alphafetoprotein gene in cell populations isolated from rat livers during carcinogenesis.
Topics: Albumins; alpha-Fetoproteins; Animals; Choline Deficiency; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Ethionine; Gene Expression Regulation; Genes; Liver; Liver Neoplasms, Experimental; Male; Methylation; Polymorphism, Genetic; Rats; Rats, Inbred Strains | 1985 |
Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.
Topics: Animals; Azacitidine; Base Sequence; Cells, Cultured; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Gene Amplification; Genes; Isoenzymes; Liver Neoplasms, Experimental; Methylation; Mice; Mutation; Polychlorinated Dibenzodioxins | 1986 |
alpha-Fetoprotein gene methylation and hepatocarcinogenesis in rats fed a choline-devoid diet.
Topics: alpha-Fetoproteins; Animals; Choline Deficiency; Gene Expression Regulation; Liver Neoplasms; Liver Neoplasms, Experimental; Methylation; Rats; Transcription, Genetic | 1987 |
DNase I hypersensitivity and methylation of the 5'-flanking region of the alpha 1-fetoprotein gene during developmental and glucocorticoid-induced repression of its activity in rat liver.
Topics: Aging; alpha-Fetoproteins; Animals; Brain; Cloning, Molecular; Deoxyribonuclease I; Dexamethasone; DNA Restriction Enzymes; Genes; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Nucleotide Mapping; Rats; Rats, Inbred Strains; Transcription, Genetic | 1986 |
Methylation of the alpha-fetoprotein gene in isogenic rat hepatoma and liver cell lines.
Topics: alpha-Fetoproteins; Animals; Cell Line; Dexamethasone; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Gene Expression Regulation; Genes; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Inbred BUF | 1987 |
Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.
Topics: 5-Methylcytosine; Albumins; alpha-Fetoproteins; Animals; Cell Line; Chromatin; Cytosine; Deoxyribonuclease I; DNA Restriction Enzymes; Gene Expression Regulation; Liver Neoplasms, Experimental; Methylation; Promoter Regions, Genetic; Rats; Transcription, Genetic | 1987 |
Albumin and alpha-fetoprotein gene expression and DNA methylation in rat hepatoma cell lines.
Topics: Albumins; alpha-Fetoproteins; Animals; Cell Differentiation; DNA, Neoplasm; Gene Expression Regulation; Genes; Liver Neoplasms, Experimental; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Albumin and alpha-fetoprotein gene expression in various nonhepatic rat tissues.
Topics: alpha-Fetoproteins; Animals; Cell Line; Chromatin; Deoxyribonuclease I; DNA; Female; Gene Expression Regulation; Kidney; Liver Neoplasms, Experimental; Methylation; Nucleic Acid Hybridization; Pregnancy; Rats; Rats, Inbred Strains; RNA, Messenger; Serum Albumin; Transcription, Genetic | 1988 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio.
Topics: Animals; Diethylnitrosamine; Genes, ras; Homocysteine; Immunoblotting; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
The role of methylation in regulating the expression of the alpha-fetoprotein gene in developing rat liver and hepatoma cell lines.
Topics: alpha-Fetoproteins; Animals; Blotting, Southern; Dexamethasone; DNA Probes; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Restriction Mapping; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Altered methylation of ras oncogenes in benzidine-induced B6C3F1 mouse liver tumors.
Topics: Animals; Benzidines; DNA Restriction Enzymes; Electrophoresis, Agar Gel; Female; Gene Expression Regulation; Genes, ras; Immunoblotting; Liver; Liver Neoplasms, Experimental; Male; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; RNA, Messenger | 1989 |
The potential role of DNA methylation in the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cell Line; Cell Nucleus; Dioxins; DNA, Neoplasm; Enhancer Elements, Genetic; Genes; Liver Neoplasms, Experimental; Methylation; Mice; Molecular Sequence Data; Oligonucleotide Probes; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Transfection | 1989 |
Inhibition of in vitro tumor cell invasion by transmethylation inhibitors.
Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Deoxyadenosines; Fibrosarcoma; Humans; Kinetics; Liver Neoplasms, Experimental; Lung Neoplasms; Melanoma, Experimental; Methylation; Neoplasm Invasiveness; Rats; Rats, Inbred Strains; Thionucleosides; Tumor Cells, Cultured | 1989 |
5-azacytidine potentiates initiation induced by carcinogens in rat liver.
Topics: Animals; Azacitidine; Carcinogens; Cocarcinogenesis; DNA; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Methylation; Rats | 1985 |
[Studies on DNA methylation in transformed mouse liver cells].
Topics: Animals; Cell Transformation, Neoplastic; DNA Modification Methylases; Liver; Liver Neoplasms, Experimental; Male; Methylation; Mice | 1989 |
Studies on hypomethylation of liver DNA during early stages of chemical carcinogenesis in rat liver.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; DNA, Neoplasm; Genes, ras; Liver Neoplasms, Experimental; Male; Methylation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping | 1989 |
Hormonal regulation of phosphoenolpyruvate carboxykinase gene expression is mediated through modulation of an already disrupted chromatin structure.
Topics: Animals; Base Sequence; Binding Sites; Chromatin; Deoxyribonuclease I; DNA, Neoplasm; Gene Expression Regulation; Insulin; Liver Neoplasms, Experimental; Methylation; Micrococcal Nuclease; Molecular Sequence Data; Nucleosomes; Phosphoenolpyruvate Carboxykinase (GTP); Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Hypomethylation of c-myc proto-oncogene of N-nitrosomorpholine--induced rat liver nodules and of H4IIE cells.
Topics: Animals; Cells, Cultured; Cytosine; DNA; Liver; Liver Neoplasms, Experimental; Male; Methylation; Nitrosamines; Phosphorus Radioisotopes; Proto-Oncogenes; Rats; Rats, Inbred Strains | 1989 |
Activation of human alpha 1-antitrypsin genes in rat hepatoma x human fibroblast hybrid cell lines is correlated with demethylation.
Topics: alpha 1-Antitrypsin; Animals; Cell Fusion; Cell Line; Chromosome Mapping; DNA Restriction Enzymes; Fibroblasts; Gene Expression Regulation; Genes; Humans; Hybrid Cells; Liver Neoplasms, Experimental; Methylation; Nucleic Acid Hybridization; Rats | 1987 |
Inhibition of steroid-inducible tyrosine aminotransferase gene expression by N-methyl-N'-nitro-N-nitrosoguanidine in a rat hepatoma cell line.
Topics: Animals; Bucladesine; Cell Line; Dexamethasone; DNA; Enzyme Induction; Gene Expression Regulation; Liver Neoplasms, Experimental; Methylation; Methylnitronitrosoguanidine; Rats; Tyrosine Transaminase | 1986 |
Biosynthesis of polylactosaminoglycans. Novikoff ascites tumor cells contain two UDP-GlcNAc:beta-galactoside beta 1----6-N-acetylglucosaminyltransferase activities.
Topics: Animals; Binding Sites; Binding, Competitive; Cations, Divalent; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucosyltransferases; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Methylation; N-Acetylglucosaminyltransferases; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Substrate Specificity | 1987 |
Biosynthesis of blood group i-active polylactosaminoglycans. Partial purification and properties of an UDP-GlcNAc:N-acetyllactosaminide beta 1----3-N-acetylglucosaminyltransferase from Novikoff tumor cell ascites fluid.
Topics: Amino Sugars; Animals; Ascitic Fluid; Blood Group Antigens; Carbohydrate Sequence; Chromatography, Gel; Glycoproteins; I Blood-Group System; Kinetics; Liver Neoplasms, Experimental; Macromolecular Substances; Magnetic Resonance Spectroscopy; Methylation; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Oligosaccharides; Rats; Rats, Inbred Strains; Substrate Specificity | 1988 |
A domain of methylation change at the albumin locus in rat hepatoma cell variants.
Topics: Albumins; Animals; Cell Line; DNA Restriction Enzymes; Gene Expression Regulation; Hybrid Cells; Liver Neoplasms, Experimental; Methylation; Phenotype; Rats; RNA, Messenger; Transcription, Genetic | 1985 |
DNA methylation and the regulation of aldolase B gene expression.
Topics: Animals; Brain; Cytosine; DNA; DNA Restriction Enzymes; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains | 1986 |
Reduced levels of histones H1o and H1b, and unaltered content of methylated DNA in rainbow trout hepatocellular carcinoma chromatin.
Topics: 5-Methylcytosine; Aflatoxin B1; Aflatoxins; Animals; Chromatin; Cytosine; DNA; Histones; Liver; Liver Neoplasms, Experimental; Methylation; Transcription, Genetic; Trout; Vitellogenins | 1987 |
DNA hypomethylation in ethionine-induced rat preneoplastic hepatocyte nodules.
Topics: Animals; Deoxycytidine; DNA; Ethionine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Precancerous Conditions; Rats; Rats, Inbred F344; Reference Values | 1988 |
c-H-ras and c-K-ras gene hypomethylation in the livers and hepatomas of rats fed methyl-deficient, amino acid-defined diets.
Topics: Amino Acids; Animals; Base Sequence; Diet; DNA; Liver; Liver Neoplasms, Experimental; Male; Methylation; Mutation; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred F344 | 1988 |
Comparative study on the indirect methylation of liver DNA guanine by the 1-carbon pool in hepatotoxicity.
Topics: Animals; Chemical Phenomena; Chemistry; Cricetinae; DNA; Formaldehyde; Guanine; Hydrazines; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylation; Mice; Species Specificity | 1987 |
DNA methylation in rat tissues by a series of homologous aliphatic nitrosamines ranging from N-nitrosodimethylamine to N-nitrosomethyldodecylamine.
Topics: Animals; DNA; Esophagus; Kidney; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylation; Nitrosamines; Organ Specificity; Rats; Rats, Inbred F344; Structure-Activity Relationship; Urinary Bladder Neoplasms | 1987 |
Oxidation of the pyridine ring: a major pathway of metabolism for the rat hepatocarcinogen, methapyrilene.
Topics: Aminopyridines; Animals; Cricetinae; Guinea Pigs; Liver Neoplasms, Experimental; Male; Methapyrilene; Methylation; Mice; Oxidation-Reduction; Pyridines; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
DNA methylation and hepatocarcinogenesis in rats fed a choline-devoid diet.
Topics: Animals; Choline Deficiency; Diet; DNA; DNA, Neoplasm; Liver; Liver Neoplasms, Experimental; Male; Methylation; Rats; Rats, Inbred F344 | 1986 |
Methylation of DNA guanine during the course of induction of liver cancer in hamsters by hydrazine or dimethylnitrosamine.
Topics: Animals; Carcinogens; Cricetinae; Dimethylnitrosamine; DNA; Guanine; Hydrazines; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Methylation; Tissue Distribution | 1987 |
Activation of a silent gene is accompanied by its demethylation.
Topics: Animals; Cell Line; Chromosome Mapping; Gene Expression Regulation; Hybrid Cells; L Cells; Leukemia, Lymphoid; Liver Neoplasms, Experimental; Melanoma; Methylation; Mice; Nucleic Acid Hybridization; Rats; Serum Albumin; Transcriptional Activation | 1985 |
A ganglioside of rat ascites hepatoma AH 7974F cells. Occurrence of a novel disialoganglioside (GD1 alpha) with a unique N-acetylneuraminosyl (alpha 2-6)-N-acetylgalactosamine structure.
Topics: Animals; Carbohydrate Conformation; Carbohydrates; Cell Line; Chromatography, Thin Layer; Clostridium; Gangliosides; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Methylation; Neuraminidase; Rats; Sphingosine | 1986 |
Formation of O6-methylguanine in rat liver DNA by nitrosamines does not predict initiation of preneoplastic foci.
Topics: Animals; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Guanine; Liver; Liver Neoplasms, Experimental; Male; Methylation; Precancerous Conditions; Rats; Rats, Inbred Strains | 1985 |
Nafenopin-induced rat liver peroxisome proliferation reduces DNA methylation by N-nitrosodimethylamine in vivo.
Topics: Animals; Cell Division; Dimethylnitrosamine; DNA; Liver; Liver Neoplasms, Experimental; Male; Methylation; Microbodies; Nafenopin; Propionates; Rats; Rats, Inbred Strains | 1985 |
Effects of denaturation and methylation on the degradation of proteins in cultured hepatoma cells and in reticulocyte cell-free systems.
Topics: Animals; Cell Line; Cell-Free System; Liver Neoplasms, Experimental; Methylation; Protein Denaturation; Proteins; Rats; Reticulocytes | 1985 |
Relationship between expression of the albumin gene and its state of methylation.
Topics: Animals; Cell Fusion; DNA; Fibroblasts; Genes; Hybrid Cells; Liver Neoplasms, Experimental; Methylation; Mice; Rats; Serum Albumin; Species Specificity; Transcription, Genetic | 1985 |