Page last updated: 2024-08-18

isomethyleugenol and Disease Models, Animal

isomethyleugenol has been researched along with Disease Models, Animal in 302 studies

Research

Studies (302)

TimeframeStudies, this research(%)All Research%
pre-199011 (3.64)18.7374
1990's13 (4.30)18.2507
2000's44 (14.57)29.6817
2010's171 (56.62)24.3611
2020's63 (20.86)2.80

Authors

AuthorsStudies
Deng, W; Jiang, M; Li, L; Wang, S1
Hamada, Y; Inada, E; Iseki, M; Katsuda, Y; Kondo, T; Kuzumaki, N; Matsufuji, M; Mori, T; Narita, M; Sato, D; Takeshima, H; Tanaka, K; Ushijima, T; Yamabe, Y; Yamaguchi, K1
Matrisciano, F; Pinna, G1
Fan, L; Shen, F; Sun, D; Wang, Z; Yang, H1
Chen, X; Dong, J; Gong, W; Guo, B; Jiang, Q; Qin, J; Shao, X; Shen, S; Shi, T; Shi, Y; Zhang, L1
Jiang, M; Shen, L; Yu, Y; Zhao, J1
Du, T; Han, R; Li, C; Li, L; Liu, R; Liu, S; Meng, K; Shen, Y; Xiu, J; Xu, L; Xu, Q; Zhu, C; Zhu, W1
Bach, DH; He, J; Huang, YH; Li, Z; Lin, P; Liu, H; Wang, Z; Yang, J1
Hou, S; Li, Y; Yang, B; Zhao, J1
Chen, Y; Gan, W; Li, D; Liu, N; Lu, Y; Ma, W; Yang, L; Yang, Z1
Chen, Y; Han, P; Lei, Y; Liu, J; Liu, M; Tian, D; Wang, H; Wang, M; Wang, S; Yan, W1
Dong, Z; Kwon, SH; Lee, BR; Lee, CM; Lee, HK; Lee, TJ; Li, C; O'Connor, PM1
Dulka, K; Fülöp, F; Gulya, K; Lajkó, N; Mihály, A; Szabo, M; Szatmári, I; Vécsei, L1
Chen, XY; Cheng, C; Cheng, WC; Dong, KY; Huang, W; Wang, YH; Yu, ZY; Zhang, L; Zuo, XZ1
Aihara, M; Araie, M; Iejima, D; Iwata, T; Kashiwagi, K; Kimura, C; Kimura, I; Mabuchi, F; Minegishi, Y; Minematsu, N; Nakayama, M; Nakazawa, T; Pan, Y; Shiga, Y; Suga, A; Takamoto, M; Yamamoto, M; Yoshitake, K1
Chen, S; Lu, YC; Pei, DS; Sun, XL; Wang, Y; Zhang, L; Zhang, LS1
Andreeva, K; Cave, MC; Head, KZ; Klinge, CM; Petri, BJ; Piell, KM; Rouchka, EC; Wahlang, B1
Adams, DA; Martin, LJ; Niedzwiecki, MV; Wong, M1
Chen, W; Han, C; Kwon, H; Ma, W; Song, K; Wu, T; Zhang, J1
Chen, HN; Dai, L; Dong, L; Fu, S; Huang, C; Luo, L; Nice, EC; Peng, Y; Shen, G; Wang, K; Wang, M; Wang, Z; Wei, X; Wu, X1
Cueto, R; Hu, W; Ji, Y; Jiang, X; Khan, M; Liu, L; Saredy, J; Sigler, D; Snyder, NW; Wang, H; Wang, X; Wu, S; Xi, H; Yang, X1
Li, SM; Ma, LL; Wang, BH; Xie, W; Xu, YQ1
Crews, FT; Dubester, K; Healey, KL; Liu, W; Miller, KM; Swartzwelder, HS1
Dai, X; He, X; Li, J; Xia, Z; Xiao, H; Yang, R1
Dai, Z; Li, Y; Qi, S; Wang, G; Wang, L; Wang, Z; Xiang, M1
Anselmo, A; Bernstein, BE; Brumbaugh, J; Charlton, J; Choi, J; Coffey, A; Di Stefano, B; Hochedlinger, K; Hock, H; Huebner, AJ; Ji, F; Kim, IS; Meissner, A; Sadreyev, RI; Schindler, JW; Schwarz, BA; Walsh, RM1
Chen, S; Feng, S; Feng, X; Guo, W; Han, M; He, Y; Huang, Y; Jiang, E; Liu, M; Liu, Y; Luo, Y; Ma, Q; Niu, Q; Pang, A; Pei, X; Su, X; Wang, Q; Wei, J; Yang, D; Zhai, W; Zhang, R1
Du, J; Gao, M; Hao, A; Ji, G; Ji, S; Li, X; Tian, W; Zhou, W1
Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D1
Artyomov, MN; Bourgeois-Daigneault, MC; Chen, J; Chubukov, V; Daigneault, A; Esaulova, E; Foulkes, W; Hayes, S; Johnson, RM; Jones, RG; Koning, R; Krawczyk, CM; Larochelle, C; Ma, EH; Mamane, V; Muhire, BM; Pospisilik, JA; Roddy, TP; Roy, DG; Samborska, B; Sheldon, RD; Shorstova, T; Steadman, M; Swain, A; Williams, KS; Witcher, M1
Khair, L; Messina, LM; Tie, G; Tutto, A; Yan, J1
Chang, CY; Chen, L; Fung, KS; Huang, LW; Hung, JH; Kao, CF; Li, J1
Chang, S; Jing, J; Li, B; Liu, X; Shangguan, S; Wang, L; Wu, J; Yao, X; Zhang, T1
Cazzola, H; Erhardt, M; Grassl, GA; Heidemann, J; Horstmann, JA; Hughes, KT; Kolbe, M; Kühne, C; Lemaire, L; Lokareddy, RK; Lunelli, M; Rossez, Y; Rossi, C; Schlüter, H; Steffen, P; Stradal, TEB; Szefs, S; Uetrecht, C; Wang, C1
Cui, S; Li, X; Ou, M; Tu, J; Zhao, S1
Chen, Q; Ji, C; Lin, K; Miao, L; Xu, A; Yang, J; Yang, L; Yu, Y; Zhang, X1
Aziz, N; Cho, JY; Han, JW; Han, SY; Kim, E; Kim, HG; Kim, JH; Kim, S; Lee, Y; Parameswaran, N; Yang, WS; Yi, YS; Yoo, BC1
Bae, WK; Hennighausen, L; Lau-Corona, D; Waxman, DJ1
Bonefas, KM; Collette, KM; Dou, Y; Garay, PM; Iwase, S; Keegan, CE; Porter, RS; Raines, B; Seo, YA; Tronson, NC; Vallianatos, CN; Wu, MC1
Ardasheva, A; Biancon, G; Dura, B; Fan, R; Flavell, RA; Fu, X; Gao, Y; Gbyli, R; Halene, S; Iwasaki, A; Joshi, P; Kudo, E; Lee, V; Li, HB; Liu, C; Liu, W; Lobben, K; Nelakanti, R; Song, Y; Tebaldi, T; Teng, R; Vasic, R; Viero, G; Wang, X; Xiao, A1
Li, P; Wang, J; Xu, X; Zhang, B; Zhang, J1
George, J; Tsuchishima, M; Tsutsumi, M1
Cai, S; Ding, Y; Lan, R; Li, J; Li, Z; Liu, P; Lu, J; Wang, J; Wang, P; Xie, T; Ye, J1
Cao, W; Fu, CY; Li, XQ; Li, ZZ; Liu, WJ; Liu, XX; Qiao, YH; Sui, Y; Zhang, XW1
Dai, D; Feng, L; Jin, H; Li, J; Li, L; Shi, R; Song, P; Wang, C; Wang, X; Zhou, Q; Zhu, L1
Feng, Y; Gong, J; Guo, J; Guo, X; He, C; He, R; Jiang, J; Li, M; Li, X; Liu, J; Miao, J; Peng, F; Qin, R; Shi, C; Tian, R; Wang, M; Wei, W; Xie, Y; Xu, S; Xu, X; Yu, S; Zhang, H; Zhao, Y; Zhu, F1
Gamu, D; Gibson, WT1
Assaraf, YG; Chen, ZS; Huang, C; Jiang, J; Li, B; Xiao, H1
Chen, XZ; Dong, YH; Gao, XQ; Ju, J; Li, PF; Li, XM; Liu, CY; Liu, F; Ponnusamy, M; Qian, LL; Shan, C; Shan, PP; Wang, K; Wang, M; Wang, T; Wang, Y; Wang, YH; Yu, T; Zhai, M; Zhang, J; Zhang, YH; Zhao, XM; Zhou, LY1
Bird, A; Chhatbar, K; Cholewa-Waclaw, J; Sanguinetti, G; Shah, R1
Feng, H; Fu, D; He, L; Zhao, H1
Agnihotri, S; Bridge, T; Hawkins, C; Huang, A; Kim, B; Li, C; Milos, S; Pajovic, S; Patel, P; Phillips, L; Rakopoulos, P; Ryall, S; Sheth, J; Siddaway, R; Srikanthan, D; Yu, M1
Bartke, A; Icyuz, M; Sun, LY; Zhang, F1
Broersen, LM; Dyall, SC; Feichtinger, RG; Hageman, RJ; Kofler, B; Lotstra, S; Michael-Titus, AT; Paredes-Esquivel, U; Priestley, JV; Rhodes, M; Silva, JP; Svendsen, L; Thau-Zuchman, O; Tremoleda, JL; van Wijk, N; Verkuyl, JM1
Allen, EG; Dai, Q; Duan, R; Guo, Z; He, C; Jin, P; Kang, Y; Li, Y; Pajdzik, K; Shafik, AM; Wu, H; Yao, B; Zhang, F1
Fan, M; Li, X; Liu, Z; Pan, S; Wang, H1
Chen, JC; Hsu, CH; Kao, SH; Lin, JM; Lin, YC1
Bhagat, G; Bilbao, JR; Castellanos-Rubio, A; Garcia-Santisteban, I; Godbout, JK; Green, PH; He, C; Herrero, L; Huerta, A; Irastorza, I; Mendoza, LM; Mera, P; Olazagoitia-Garmendia, A; Rodriguez, JA; Sebastian-DelaCruz, M; Serra, D; Verdu, EF; Zhang, L1
Cao, Z; Jia, M; Li, S; Li, W; Li, Z; Liu, H; Su, M; Sun, Y1
Anderson, EN; Basso, M; Caricasole, A; Grant, RA; Hernández, IH; Lucas, JJ; Migazzi, A; Pandey, UB; Pennuto, M; Ratovitski, T; Roccuzzo, M; Ross, CA; Saudou, F; Scaramuzzino, C; Tosatto, L; Tripathy, D; Virlogeux, A; Zuccato, C1
Du, L; Xu, S; Xu, X; Yan, L; Zhang, L; Zhang, Z1
Alinari, L; Baiocchi, RA; Brown, F; Chung, JH; Courtney, LE; Kisseberth, WC; Klamer, BG; Long, M; Ozer, HG; Renaldo, KA; Scherle, P; Schlotter, S; Shilo, K; Sloan, SL; Vaddi, K; Valli, VE; Yilmaz, AS; Youssef, Y; Zhang, X1
An, Q; An, S; Chen, S; Gu, X; Li, R; Sun, C; Wang, Z1
Ding, L; Liu, D; Wang, X; Xu, H; Zhou, X; Zhu, Y1
Abisambra, JF; Alvarez, VE; Ash, PEA; Boudeau, S; Cheng, JX; Crary, JF; Cruz, AL; Emili, A; Hovde, S; Jiang, L; Kanaan, N; Kuo, MH; Kwan, J; Lei, S; Li, H; Lin, W; Maziuk, BF; Murray, ME; Petrucelli, L; Song, J; van Vliet, E; Verma, M; Wolozin, B; Yang, Z; Zhang, C; Zhao, J1
Chater-Diehl, EJ; Laufer, BI; Singh, SM1
Crabbe, JC; Gavin, DP; Guizzetti, M; Hashimoto, JG; Wiren, KM1
Bain, G; Calderon, I; Darlington, J; Evans, JF; Goulet, L; Huang, F; Hutchinson, JH; King, CD; Lai, A; Lasof, T; Lonergan, D; Ma, GL; MacKenna, DA; Nguyen, K; Prodanovich, P; Rowbottom, MW; Santini, AM; Shannon, KE1
Thomas, EA1
Bassi, S; Biagioli, M; Di Leva, F; Monziani, A; Tripathi, T1
Dragunow, M; Narayan, P1
Binó, L; Bittová, M; Drápela, S; Ešner, M; Fedr, R; Hampl, A; Hylse, O; Jaroš, J; Khirsariya, P; Kolářová, H; Kollár, P; Krejčí, L; Nikulenkov, F; Ovesná, P; Paruch, K; Samadder, P; Souček, K; Straková, N; Suchánková, T; Vaňhara, P; Vašíčková, K1
Aripovsky, A; Kulagina, T; Savina, T1
Bailis, W; Batista, PJ; Broughton, JP; Cao, G; Chang, HY; Chen, Y; Chen, YG; Duffy, EE; Flavell, RA; Kluger, Y; Kroehling, L; Li, HB; Simon, MD; Tong, J; Wang, G; Yin, Z; Zhao, J; Zhu, S1
Chen, XM; Gong, AY; Li, M; Mathy, NW; Ming, Z; Strauss-Soukup, JK; Wang, Y; Zhang, XT1
Durban, VM; Phesse, TJ; Sansom, OJ1
Borkin, D; Cierpicki, T; Grembecka, J; Kempinska, K; Klossowski, S; Malik, B; Miao, H; Shukla, S; Wang, J1
Arancio, O; Asam, K; Huber, KL; Mazzeo, A; Melideo, SL; Nicholls, RE; Pérez, E; Staniszewski, A; Stock, JB; Stock, M; Voronkov, M; Zhang, H1
Bai, J; Chen, S; Gao, J; Li, H; Pu, J; Shuai, X; Tao, K; Wang, G; Wang, J; Wu, K; Yin, Y1
Cai, W; Ding, Z; Feng, X; Hong, X; Hou, J; Huang, H; Li, Y; Qiu, X; Sha, R; Song, H; Zhang, Z; Zhao, J; Zhu, Y; Zhuo, H1
Shimura, C; Shinkai, Y; Yamada, A1
Chen, D; Cheng, L; Liu, Y; Wang, Y; Xiao, L; Yan, N; Zhang, J; Zheng, S1
Alkhayer, K; Clements, R; Freeman, E; McDonough, J; Shelestak, J; Singhal, NK1
Benevento, M; Dubos, A; Feil, R; Habibi, E; Herault, Y; Iacono, G; Kasri, NN; Kleefstra, T; Mandoli, A; Méziane, H; Riet, F; Selloum, M; Stunnenberg, HG; van Bokhoven, H; Zhou, H1
Du, J; Fang, TK; Yan, CJ1
Bao, S; Cai, W; Ding, Y; Li, M; Li, Z; Sun, Y; Xie, Q; Yin, R; Zhou, T1
Chen, Y; Jiang, R; Luo, H; Qiu, Z; Wang, Y; Yu, P; Zhu, D1
Agrawal, DK; Boosani, CS; Jiang, W1
Kaneko, S; Li, X1
Baric, RS; Dinnon, KH; Graham, RL; Gralinski, LE; Leist, SR; McAnarney, ET; Menachery, VD; Mitchell, HD; Waters, KM; Yount, BL1
Huang, M; Wang, Z; Yu, Q; Yu, X; Zeng, X; Zhang, J; Zhao, W; Zhu, M1
Absher, D; Becker, A; Benson, D; Brinkley, GJ; Buckhaults, PJ; Carobbio, F; Chen, J; Crossman, DK; Dutta, S; Emberley, E; Huang, T; Kirkman, R; Kundu, A; Kunick, C; Ogawa, S; Pan, A; Parekh, V; Poston, T; Rakheja, D; Sato, Y; Shelar, S; Shim, EH; Sudarshan, S; Tan, J; Velu, SE1
Chen, Q; Chen, S; Chen, Z; Li, J; Mi, JQ; Pandolfi, PP; Sun, H; Weng, X; Xu, J; Yan, X; Zhang, W; Zhao, C; Zhao, J; Zhu, J; Zhu, Y1
Anczurowski, M; Arrowsmith, CH; Butler, MO; Guo, T; Hirano, N; Kagoya, Y; Matsunaga, Y; Murata, K; Saijo, H; Saso, K; Sugata, K; Wang, CH1
Alahmari, B; Choi, J; Cooper, M; DiPersio, JF; Ritchey, J; Ziga, E1
Bator, E; Bilecki, W; Głowacka, U; Latusz, J; Maćkowiak, M1
Alves-Wagner, AB; Correa-Giannella, ML; Esteves, JV; Giannella-Neto, D; Machado, UF; Okamoto, MM; Yonamine, CY1
Friedman, N; Geula, S; Gillis, E; Hanna, JH; Lasman, L; Le-Trilling, VTK; Mandelboim, M; Nachshon, A; Safra, M; Schwartz, S; Soyris, C; Stern-Ginossar, N; Tai-Schmiedel, J; Trilling, M; Winkler, R1
Hwang, H; Jiang, Y; Li, Y; Wang, J; Wang, P; Wang, X; Yang, X1
Adams, PD; Birse, RT; Bodmer, R; Dall'Agnese, A; Diop, SB; Guida, MC; Mai, A; Puri, PL; Toto, PC1
Fu, Y; Repunte-Canonigo, V; Sanna, PP; Sumazin, P; Zorman, B1
Greengard, P; Hu, Z; Lin, L; Liu, T; Ma, K; Matas, E; Seo, JS; Wang, J; Wang, ZJ; Yan, Z; Yang, F; Zhang, F; Zhong, P1
Cao, Q; Chen, GJ; Cheng, J; Lin, L; Liu, A; Ma, K; Matas, E; Wang, W; Wang, X; Wang, ZJ; Wei, J; Yan, Z; Zhang, F; Zheng, Y1
Hara, A; Imakita, N; Ito, T; Kasahara, K; Kitabatake, M; Matsukawa, A; Mikasa, K; Morita-Takemura, S; Ouji-Sageshima, N; Wanaka, A1
Tamura, A1
Amin, MA; Campbell, P; Coit, P; Fox, DA; Khanna, D; Miller, S; Sawalha, AH; Tsou, PS1
Botaitis, S; Franco, R; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Vasantha Rupasinghe, HP; Zoumpourlis, V1
Gupta, R; Saha, P; Sen, N; Sen, T1
Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R1
Ali, S; Chen, X; Guo, M; Huang, H; Huang, Y; Qie, S; Wang, J; Wang, S; Yu, C; Zhang, L; Zheng, X1
Hu, C; Qin, L; Qiu, K; Tan, Y; Wang, L; Wu, G1
Huang, X; Liu, L; Pan, B; Tian, J; Wang, Z; Wu, X; Zhao, W1
Caillier, SJ; Cantó, E; Condello, C; Didonna, A; Hauser, SL; Isobe, N; Mofrad, MRK; Oksenberg, JR; Shams, H; Tiwari-Woodruff, SK; Yamate-Morgan, H; Zhao, C1
Bai, Y; Cheng, J; Liu, H; Tao, J; Xiao, Q; Zhao, Q; Zhu, Y1
Lee, IS; Sang Cho, K; Song, B1
Amini, B; Bergsagel, PL; Davis, RE; Gagel, RF; He, J; Hou, J; Koh, SP; Lee, HC; Li, Z; Lin, P; Liu, H; Liu, Z; Navone, NM; Orlowski, RZ; Starbuck, MW; Tam, BT; Tong, Q; Wang, Z; Xiao, M; Yang, J; Yi, Q; Young, KH; Zhang, Y; Zhong, Y1
Chen, J; Lin, N; Lu, Y; Xu, M; Xu, R; Yao, Z; Yuan, L; Zhou, S; Zou, X1
Jiang, H; Khodadadi-Jamayran, A; Shah, K; Yang, Z1
Cheng, L; Dong, Z; Gong, H; Li, KE; Shu, S; Shu, X1
Hewitson, TD; Holt, SG; Samuel, CS; Smith, ER; Wigg, B1
Han, R; Wu, Q; Xiu, R; Yuan, X; Zhang, H1
Baeza, I; Claus, SP; de Castro, NM; de la Fuente, M; Yaqoob, P1
Contestabile, A; Sintoni, S1
Monti, B1
Monti, B; Peña-Altamira, LE; Polazzi, E1
Deng, YQ; Dong, H; Leng, QB; Li, SH; Li, XF; Qin, CF; Qin, ED; Shi, PY; Wang, HJ; Wang, XY; Xie, X; Ye, Q; Zhang, B; Zhao, H; Zhu, SY; Zuest, R1
Berger, M; Hoebe, K; Kono, DH; Lawson, BR; Manenkova, Y; Tardif, V; Theofilopoulos, AN; Yuan, C; Zuo, JP1
Aggarwal, T; Casci, I; Fackelmayer, FO; Lanson, NA; Maltare, A; Milioto, C; Monaghan, J; Pandey, UB; Pennuto, M; Scaramuzzino, C1
Donaghy, J; Horowitz, JC; Huang, SK; Peters-Golden, M; Przybranowski, S; Scruggs, AM; White, ES; Zaslona, Z1
Akula, MK; Bergo, MO; Fong, LG; Ibrahim, MX; Liu, M; Sayin, VI; Young, SG1
Ghosh, S; Liu, B; Wang, Z; Zhang, L; Zheng, H; Zhou, Z1
Chen, W; Hu, J; Hu, S; Huang, LY; Jiang, X; Wang, YM; Xiao, Y; Xu, GY; Zhang, HH; Zhou, YL1
Blom, HJ; Castro, R; de Vriese, AS; Esse, R; Florindo, C; Imbard, A; Rocha, MS; Smulders, YM; Tavares de Almeida, I; Teerlink, T1
Davidge, ST; Hardy, DB; Morton, JS; Osumek, JE; Revesz, A1
Cabezas-Herrera, J; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L1
Li, L; Rong, R; Wang, J; Xu, M; Zhu, T1
Arning, E; Bottiglieri, T; Gibson, KM; Vogel, KR; Wasek, BL1
Bame, M; Brusilow, WS; Grier, RE; Needleman, R1
Chen, P; Chen, Y; He, Z; Peng, H; Zeng, H; Zhang, H; Zhang, Y1
Abdel-Wahab, O; Aburatani, H; Enomoto, Y; Harada, H; Harada, Y; Heuser, M; Inoue, D; Isobe, M; Izawa, K; Kagiyama, Y; Kawabata, KC; Kimura, H; Kitamura, T; Kitaura, J; Levine, RL; Maehara, A; Nakahara, F; Nishimura, K; Ochiya, T; Oki, T; Thol, F; Togami, K; Tsuchiya, A; Uchida, T1
Kim, Y; Kowall, NW; Lee, J; Park, E; Ryu, H1
Boemke, W; Francis, RC; Höhne, C; Neubert, F; Pickerodt, PA; Swenson, ER; Telalbasic, S1
Blom, HJ; Castro, R; Davids, M; Esse, R; Florindo, C; Gupta, S; Imbard, A; Kruger, WD; Quinlivan, EP; Tavares de Almeida, I; Teerlink, T1
Antignano, F; Arrowsmith, CH; Braam, MJ; Burrows, K; Chenery, AL; Fung, TC; Gold, MJ; Han, JM; Hughes, MR; Kron, KJ; Levings, MK; Lupien, M; McNagny, KM; Min, PH; Oudhoff, MJ; Penrod, NM; Rossi, FM; Wang, SK; Zaph, C1
Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C1
Baek, JH; Rubinstein, M; Scheuer, T; Trimmer, JS1
Aparicio, SA; Berg, T; Bilenky, M; Chang, H; Cheng, SW; Gascoyne, RD; Hirst, M; Humphries, RK; Lai, CK; Lai, D; Lee, S; Lim, E; Marra, MA; Morin, GB; Morin, RD; Mungall, AJ; Oellerich, T; Rosten, P; Salmi, A; Schoeler, N; Serve, H; Thoene, S; Umlandt, P; Wee, T; Yap, D; Yue, L1
Chen, J; Dou, X; Li, S; Qian, Y; Song, Z; Xia, Y; Zhang, X1
Barbash, O; Butte, AJ; Dhanak, D; Garcia, BA; Gozani, O; Huddleston, M; Jansen, PW; Khatri, P; Kruger, RG; Liu, S; Mazur, PK; Reynoird, N; Sage, J; Tummino, PJ; Van Aller, GS; Vermeulen, M; Wilkinson, AW1
Gao, K; Liu, Z; Rong, H; Wan, Q; Wang, G; Wang, H; Wang, X; Wu, M1
Charlton, CG; Dent, L; Griffin, B; King, J; Mackey, V; Muthian, G; Smith, ML1
Dawn, B; Elias, HK; Malik, AB; Rajasingh, J; Rajasingh, S; Simpson, AD; Sundivakkam, PK; Thangavel, J; Vogel, SM; Xuan, YT1
Basurto-Islas, G; Blanchard, J; Fernandez, JR; Iqbal, K; Stock, JB; Stock, M; Tung, YC; Voronkov, M; Zhang, S1
Emery, R; Hodges, SJ; Oguz, C; Pitsillides, AA; Soper, RJ1
Cao, JL; Peng, YN; Tang, LH; Wang, Y; Yan, M; Yu, LN; Zhou, XL1
Cai, C; Chai, R; He, Y; Li, H; Sun, S; Yu, H1
Kuang, D; Liu, J; Liu, T; Wu, Y; You, L; Zheng, Y1
Eissenberg, JC; Florens, L; Gao, X; Herz, HM; Jackson, J; Morgan, M; Rickels, R; Shilatifard, A; Swanson, SK; Washburn, MP1
Cui, W; Kong, L; Li, X; Luo, M; Miao, L; Tan, Y; Wu, H; Xu, F; Zhou, S1
Agrawal, R; Gomez-Pinilla, F; Tyagi, E; Ying, Z; Zhuang, Y1
Bearss, J; Gajiwala, S; Janat-Amsbury, M; Sharma, S; Sorna, V; Theisen, ER1
Berglund, JA; Coonrod, LA; Copperman, J; deLorimier, E; Guenza, MG; Reister, EE; Sharma, K; Taber, A; Todd, PK1
Huang, W; Ling, W; Peng, C; Xia, M; Xiao, Y; Zhang, J1
García, A; Hinrichsen, LI; Lamas, MC; Leonardi, D; Vasconi, MD1
Albrecht, BK; Arora, S; Audia, JE; Balasubramanian, S; Bradley, WD; Bryant, BM; Busby, J; Campbell, R; Cantone, N; Cook, AS; Cummings, RT; Dakin, LA; Daniels, DL; Garapaty-Rao, S; Gehling, VS; Harmange, JC; Hatton, C; Iyer, P; Méndez, J; Nasveschuk, CG; Normant, E; Trojer, P; Vaswani, RG; Williamson, KE; Yuan, CC; Zhao, F1
Georgieff, MK; Kennedy, BC; Lien, YC; Simmons, RA; Tran, PV1
Cai, Q; Chen, X; Dong, W; Gu, P; He, W; Huang, J; Lin, T; Wang, B; Xie, W; Xie, Y; Zhong, G1
Ozanne, SE1
Berger, H; Chin, KC; Gingras, AR; Ginhoux, F; Gunawan, M; Guo, T; La Win, MK; Li, LY; Loh, JT; Neo, WH; Ng, LG; See, PC; Shochat, SG; Su, IH; Sze, SK; Venkatesan, N; Wong, JF; Yamazaki, S; Yau, YH1
Fan, Z; Jia, Z; Liu, D; Song, J; Wang, J; Wang, L; Wang, S; Wang, Y; Yang, D1
DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K1
Fan, Y; Fang, J; Han, S; He, X; Heng, D; Li, L; Liu, W; Peng, B; Wang, Z; Yin, J1
Cadet, JL; Godino, A; Jayanthi, S1
Nachman, PH; Pendergraft, WF1
Chen, W; Hu, S; Jiang, GQ; Jiang, X; Wei, J; Xu, GY; Zhang, HH; Zhou, YL; Zhu, H1
Aguilar, DD; Carless, MA; Giuffrida, A; Lodge, DJ; Neary, JL; Perez, SM1
Bollag, WB; Choi, JH; Figueroa, M; Li, X; Liu, F; Liu, K; Lu, C; Nayak-Kapoor, A; Oberlies, NH; Paschall, AV; Pearce, C; Yang, D1
Aldámiz-Echevarría, L; Andrade, F; Aspichueta, P; Barbier-Torres, L; Beraza, N; Falcon-Perez, JM; Fernandez, ML; Fernández-Ramos, D; Fernandez-Tussy, P; García-Monzón, C; García-Rodríguez, JL; Juan, VG; Lage-Medina, S; Lopitz-Otsoa, F; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Martínez-Uña, M; Mato, JM; Varela-Rey, M; Wagner, C; Woodhoo, A; Zubiete-Franco, I1
Kitanaka, C; Kurachi, H; Kuramoto, K; Nagase, S; Ohta, T; Okada, M; Sakaki, H; Seino, M; Seino, S; Suzuki, S; Takeda, H; Watarai, H1
Baek, SH; Bhin, J; Hwang, D; Kim, C; Kim, D; Kim, Y; Koh, GY; Lee, H; Lee, J; Nam, HJ; Park, DY; Park, SW; Yu, YS1
Agarwal, S; Badeaux, AI; Brookes, E; Chen, C; Egan, B; Gu, L; Ito, H; Iwase, S; Kasza, T; Kwan, KY; Lin, G; Sartor, MA; Shi, Y; Thompson, A; Tomassy, GS; Vallianatos, CN; Xu, J1
Bigaud, E; Corrales, FJ1
Boeynaems, S; Bogaert, E; Callaerts, P; Cruts, M; Cuijt, I; De Baets, G; Gijselinck, I; Gitler, AD; Jovičić, A; Michiels, E; Robberecht, W; Rousseau, F; Scheveneels, W; Schymkowitz, J; Sieben, A; Steyaert, J; Van Broeckhoven, C; Van Damme, P; Van Den Bosch, L; Verstrepen, KJ1
Bernstein, D; Chang, CP; Chen, CH; Chen, HS; Cheng, HL; Cheng, W; Drakos, SG; Ghetti, A; Han, P; Hang, CT; Li, DY; Li, W; Lin, CH; Quertermous, T; Shang, C; Wong, J; Xiong, Y; Yang, J; Zhao, M1
Bhatti, B; Idris, MM; Kumar, A; Mandal, KK; Meena Lakshmi, MG; Meghah, V; Narasimha Murthy, ChL; Poruri, A; Purushothaman, S; Sarath Babu, N; Saxena, S1
Lei, PJ; Li, L; Li, YM; Wang, HY; Wei, G; Wu, M; Ye, M; Zhang, X; Zhao, J; Zhao, QY; Zheng, JY1
Hwangbo, MH; Kim, IK; Lee, HA; Park, KM; Seok, YM1
Alberry, BL; Castellani, CA; Chater-Diehl, EJ; Laufer, BI; Singh, SM1
Cheng, SY; Fu, L; Gao, D; Wu, H; Zhang, L; Zhao, Y1
Bae, GU; Bang, SY; Han, JW; Jeon, YJ; Kozma, SC; Lee, J; Lee, MG; Lee, SJ; Nam, KH; Park, EK; Park, JW; Rhie, JW; Thomas, G; Um, SH; Yi, SA; Yoo, JH; You, JS1
Buechele, C; Cleary, ML; Duque-Afonso, J; Gozani, O; Hansen, L; Huang, M; Ikenouye, L; Klein, BJ; Kutateladze, TG; Li, Q; Majeti, R; Martin, GM; Onishi, M; Schneidawind, D; Shen, J; Wong, SH; Zhu, F; Zhu, L1
Judson, RN; Kast, J; Liu, DY; Rossi, FM; Zhang, RH1
Agger, K; Helin, K; Johansen, JV; Kooistra, SM; Miyagi, S; Pedersen, MT1
Guo, G; Ramadoss, S; Wang, CY1
Fang, Y; Gao, J; Guo, X; Huang, M; Liu, C; Qi, X; Ruan, H; Shen, W; Xu, M; Zheng, J1
Cho, H; Choi, D; Ho, WK; Jeon, D; Jeong, MH; Jung, CY; Jung, S; Kang, JS; Kang, K; Kim, H; Kim, HJ; Kim, KR; Kim, SH; Kim, ST; Koh, J; Koo, SH; Lee, SY; Park, JM; Park, SK; Sohn, JW; Vuong, TA; Yang, H1
Alisch, RS; Chen, L; Chopra, P; Jin, P; Keleş, S; Li, S; Madrid, A; Papale, LA; Zhang, Q1
Kamejima, S; Ohkido, I; Okabe, M; Tatsumi, N; Uchiyama, T; Waku, T; Yokoo, T; Yokoyama, K1
Cackowski, FC; Decker, AM; Franceschi, RT; Jung, Y; Lee, E; Li, Y; Pienta, KJ; Taichman, RS; Wang, J; Yumoto, K1
Guo, W; Jia, Y; Jiang, Y; Sun, Y; Tian, J; Wang, Y; Yang, A; Yang, X; Zhang, H; Zhu, G1
Kong, Y; Sun, Q; Xu, X; Yang, X; Zhan, Y; Zhang, J1
Ainslie, KM; Amici, SA; Bachelder, EM; Baiocchi, RA; Green, PL; Guerau-de-Arellano, M; Jablonski, KA; Karkhanis, V; Li, C; Li, L; Panfil, AR; Peine, K; Savardekar, H; Webb, LM; Zhou, W1
Dai, RP; Hu, ZL; Huang, FL; Huang, YQ; Li, CQ; Li, F; Qiao, XQ; Wang, HT; Zhang, WJ1
Azadi, P; Baker, S; Black, I; Brown, N; Davies, MR; Donohue, N; Heiss, C; Kaye, PM; Kintz, E; van der Woude, M1
Chen, D; Cong, G; Hou, J; Huang, H; Jia, S; Jin, P; Wang, K; Yan, N; Yan, R; Zhang, N1
Akimoto, Y; Beltcheva, O; Fukutomi, T; Hada, I; Ito, Y; Katada, T; Katayama, K; Kimura, T; Kudo, A; Kurayama, R; Nishibori, Y; Suehiro, J; Takahashi, S; Tryggvason, K; Yan, K1
Dai, X; Fang, F; Fang, M; Qi, X; Xu, H; Xu, Y; Yu, L1
Gorelik, G; Jeffries, M; Johnson, K; Knowlton, N; Lu, Q; Osban, J; Ray, D; Richardson, B; Sawalha, AH; Webb, R1
Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN1
Barbosa-Morais, NL; Conboy, CM; Fisher, EM; Odom, DT; Schmidt, D; Tavaré, S; Tybulewicz, VL; Vanes, L; Wilson, MD1
Cheung, N; So, CW; Yeung, J; Zeisig, BB1
Bardag-Gorce, F; Dedes, J; French, BA; French, SW; Li, J; Oliva, J1
Anilkumar, N; Cave, AC; Kentish, JC; Layland, J; Marshall, M; Shah, AM; Walker, SJ1
Deussen, A; Henle, T; Herrmann, M; Pexa, A; Taban-Shomal, O1
Brody, SL; Cannon, CL; Capps, GH; Hindi, KM; Hogue, LA; Ibricevic, A; Kascatan-Nebioglu, A; Vajravelu, RK; Walter, MJ; Youngs, WJ1
Kodadek, TJ; Kumar, A; LaPlant, Q; Nestler, EJ; Renthal, W; Sikder, D; Wilkinson, MB; Xiao, G1
Allen, RM; Carson, WF; Cavassani, KA; Coelho, AL; Corsa, CA; Dou, Y; Hogaboam, CM; Ishii, M; Kunkel, SL; Li, X; Liu, T; Lukacs, NW; Wen, H1
de Jong, PH; Glansbeek, HL; Hagenaars, N; Heldens, JG; Hennink, WE; Jiskoot, W; Mastrobattista, E; Mooren, I; van den Bosch, H; Verheul, RJ1
Delgado, JM; Jiménez-Capdeville, ME; Ortiz-Pérez, D; Ríos, R; Santoyo, ME; Zarazúa, S1
Kuroda, Y; Moritomo, H; Murase, T; Okada, K; Okamoto, M; Tanaka, H; Temporin, K; Yoshikawa, H1
Bardag-Gorce, F; French, BA; French, SW; Li, J; Lu, SC; Oliva, J1
Costa, E; Davis, JM; Guidotti, A; Kadriu, B; Pibiri, F; Tueting, P; Veldic, M1
Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S1
Chen, Y; Fang, Y; Jang, Y; Wei, L; Wu, X; Yan, G; Yi, L; Zhou, X1
Benbrahim-Tallaa, L; Lunn, R; Sams, RL; Tokar, EJ; Waalkes, MP; Ward, JM1
Baldwin, KM; Bodell, PW; Haddad, F; Jiang, W; Qin, AX1
Pertino, MW; Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C1
Bui, PH; Handforth, A; Hankinson, O; Homanics, GE; Quesada, A1
Agellon, LB; Li, Z; Vance, DE1
Braithwaite, SP; Chao, Y; Chen, W; Feng, X; Fernandez, JR; Grosso, H; Im, JY; Junn, E; Lee, KW; Masliah, E; Mouradian, MM; Ray, N; Sonsalla, PK; Stock, JB; Voronkov, M1
Belshaw, N; Hindmarsh, A; Johnson, IT; Mehta, S; Rhodes, M1
Bertolo, RF; Brophy, JD; MacKay, DS; McBreairty, LE; McGowan, RA1
Cameron, CE; Eshghi, A; Frank, A; Haake, DA; Pinne, M; Zuerner, RL1
Allen, RH; Greiner, LS; Jiang, H; Maclean, KN; Stabler, SP1
Chen, JK; Cheung, P; Gozani, O; Ishibe-Murakami, S; Kuo, AJ; Patel, DJ; Song, J; Yamazoe, S1
Ilnytskyy, S; Kolb, B; Kovalchuk, A; Kovalchuk, O; Lowings, M; Muhammad, A; Rodriguez-Juarez, R1
Cvetkovic, T; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Sokolovic, D; Stevanovic, I; Stojanovic, I1
Baker, SJ; Becksfort, J; Bouffet, E; Chalhoub, N; Chen, X; Cohn, R; Curley, N; Ding, L; Dooling, DJ; Downing, JR; Easton, J; Ellison, DW; Finkelstein, D; Fulton, LL; Fulton, RS; Gajjar, A; Gilbertson, RJ; Gupta, P; Gururangan, S; Hassall, T; Hedlund, E; Hong, X; Huether, R; Kawauchi, D; Kranenburg, TA; Kriwacki, R; Lau, CC; Li, S; Lin, T; Lu, C; Ma, J; Mardis, ER; Ochoa, K; Onar-Thomas, A; Parker, M; Paugh, S; Phoenix, TN; Pounds, S; Robinson, G; Roussel, MF; Rusch, M; Thiruvenkatam, R; Vadodaria, B; Wang, J; Wei, L; Wilson, RK; Wu, G; Zhang, J; Zhao, D; Zhu, X1
Halsted, CH; Medici, V1
Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Chan, JP; Festenstein, R; Goula, AV; Merienne, K; Stys, A; Trottier, Y1
Bollag, G; Bornman, WG; Davies, MA; Dayyani, F; Desai, J; Gallick, GE; Gopal, YN; Jiang, ZQ; Kopetz, S; Lemos, R; Mao, M; Mariadason, JM; Mills, GB; Powis, G; Tang, XM; Tian, F; Tsao, CC; Wistuba, II1
Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L1
Burda, J; Martín de la Vega, C; Salinas, M; Toledo Lobo, MV1
Demidem, A; Madelmont, JC; Morvan, D; Papon, J1
Ji, C; Kaplowitz, N1
Moore, AR1
Seed, MP1
Chai, HB; Chávez, D; Cordell, GA; Díaz, F; Fairchild, CR; Farnsworth, NR; Kardono, LB; Kinghorn, AD; Lee, D; Mi, Q; Pezzuto, JM; Riswan, S; Tan, GT; Wild, R1
Albanes, D; Glynn, SA1
Arnhold, T; Caudill, MA; Collins, MD; Fahr, SH; Henning, SM; Mao, GE; Nau, H; Santos-Guzmán, J; Swendseid, ME; Wagner, C; Wang, JC1
Buettner, R; Corzilius, L; Doerfler, W; Dorn, A; Hilger-Eversheim, K; Hohlweg, U; Hösel, M; Niemann, A; Remus, R; Schmitz, B; Schramme, A; Webb, D1
Martin, CC; O'Brien, RM; Oeser, JK1
Bibby, MC; Blackburn, A; Lucock, MD; Nicolaou, A1
Beal, MF; Browne, SE; Choi, DK; Ferrante, RJ; Gardian, G; Gregorio, J; Klivenyi, P; Kubilus, JK; Langley, B; Ratan, RR; Ryu, H1
Costa, E; Davis, J; Dong, E; Doueiri, MS; Grayson, DR; Guidotti, A; Pinna, G; Rodriguez-Menendez, V; Tremolizzo, L; Tueting, P1
Chen, LY; Du, YM; Liu, SQ; Peng, H; Qiu, B1
Braig, M; Dörken, B; Jenuwein, T; Lee, S; Loddenkemper, C; Peters, AH; Rudolph, C; Schlegelberger, B; Schmitt, CA; Stein, H1
Berton, O; Kumar, A; Nestler, EJ; Neve, RL; Renthal, W; Tsankova, NM1
Bhattacharya, SK; Bonilha, VL; Crabb, JS; Crabb, JW; Gu, X; Takahara, H1
Aldape, K; Black, PM; Chakravarti, A; Erkkinen, MG; Gilbert, MR; Loeffler, JS; Mehta, M; Nestler, U; Stupp, R1
Bucana, CD; Chakravarty, G; El-Naggar, AK; Jasser, SA; Kim, S; Myers, JN; Santillan, AA; Wang, Z; Yazici, YD; Younes, MN1
Bundle, SF; Carson, JP; McGill, BE; Thaller, C; Yaylaoglu, MB; Zoghbi, HY1
Harris, MJ; Juriloff, DM1
Cmejla, R; Cmejlova, J; Elleder, M; Man, P; Myslivcova, D; Petrak, J; Vulpe, CD; Vyoral, D1
Cormier, K; Del Signore, SJ; Ferrante, RJ; Goldstein, DR; Goodrich, S; Hagerty, SW; Luthi-Carter, R; Markey, AL; Matson, S; Ryu, H; Smith, K; Soh, BY; Stack, EC1
Muriel, P; Perez-Alvarez, V; Rivera, H; Shibayama, M; Tsutsumi, V1
Ghosh, AK; Varga, J1
Alberto, JM; Blaise, S; Bronowicki, JP; Delabar, JM; Guéant, JL; Hamelet, J; Janel, N; Noll, C1
Allgood, JC; Dillehay, DL; Merrill, AH; Moody, SJ; Morales, PR; Pallas, DC; Pruett, S; Symolon, H1
Amidi, F; Bardag-Gorce, F; Dedes, J; Fraley, S; French, B; French, SW; Li, J; Oliva, J; Villegas, J1
Prewitt, AK; Westberry, JM; Wilson, ME1
Bezard, E; Brotchie, JM; Fox, SH; Hallett, PJ; Lubin, FD; Nicholas, AP; Ravenscroft, P; Standaert, DG; Sweatt, JD; Vattem, P; Zhou, S1
DeSimone, J; Heller, P1
Dinn, JJ; McCann, S; Reed, B; Scott, JM; Weir, DG; Wilson, P1
Limas, CJ1
Bottiglieri, T; Hyland, K; Reynolds, EH1
Berns, A; Breuer, ML; Hershfield, MS; Migchielsen, AA; Ossendorp, F; te Riele, H; Toutain, S; Valerio, D; van Roon, MA; Zurcher, C1
Iwai, H1
Adam-Rodwell, G; Morse, MA; Stoner, GD1
Counts, JL; Goodman, JI1
Andrews, JS; de Boer, T; Gibson, S; Plate, R; Plaum, MJ; Rae, DR1
Hoogeveen, AT; Oostra, BA1
Kitchin, KT1
Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD1
Finnell, RH; Gelineau-van Waes, J1
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN1
Campbell, C; Hillman, RS; McGuffin, R1
Metz, J1
Espina, N; Garro, AJ; McBeth, D; Wang, SL; Wu-Wang, CY1
Monk, M1
Gerhardt, KO; Katz, ML1
Joosten, LA; Schalkwijk, J; van de Putte, LB; van den Berg, WB1
Chanarin, I; Deacon, R; Green, R; Lumb, M; Perry, J; Purkiss, P1
Goldsworthy, TL; Hanigan, MH; Pitot, HC1
De Bault, LE; Desai, LS; Foley, GE; Morrissey, G1
Nagai, Y; Nakano, K1
Jervis, HR; Sheahan, DG; Sprinz, H; Takeuchi, A1
Ryan, SF1
Carlo, IA; Kottke, BA; Subbiah, MT; Weaver, KM1

Reviews

38 review(s) available for isomethyleugenol and Disease Models, Animal

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Identification of methylation-regulated genes modulating microglial phagocytosis in hyperhomocysteinemia-exacerbated Alzheimer's disease.
    Alzheimer's research & therapy, 2023, 10-03, Volume: 15, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Humans; Hyperhomocysteinemia; Methylation; Mice; Mice, Transgenic; Microglia; Phagocytosis

2023
Metabolism of N-nitrosodimethylamine, methylation of macromolecules, and development of hepatic fibrosis in rodent models.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:9

    Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Disease Susceptibility; Fibroblasts; Fibrosis; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Macromolecular Substances; Methylation; Rodentia

2020
Reciprocal skeletal phenotypes of PRC2-related overgrowth and Rubinstein-Taybi syndromes: potential role of H3K27 modifications.
    Cold Spring Harbor molecular case studies, 2020, Volume: 6, Issue:4

    Topics: Acylation; Animals; Disease Models, Animal; Histones; Humans; Lysine; Methylation; Mice; Polycomb-Group Proteins; Rubinstein-Taybi Syndrome

2020
Surmounting cancer drug resistance: New insights from the perspective of N
    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2020, Volume: 53

    Topics: Adenosine; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Disease Models, Animal; DNA Damage; DNA Repair; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Methylation; Neoplasms; Protein Kinase Inhibitors; RNA Processing, Post-Transcriptional; Treatment Outcome; Tumor Microenvironment

2020
Serine, glycine and one‑carbon metabolism in cancer (Review).
    International journal of oncology, 2021, Volume: 58, Issue:2

    Topics: Animals; Antineoplastic Agents; Carbon; Carcinogenesis; Disease Models, Animal; Glycine; Humans; Metabolic Networks and Pathways; Methylation; Mice; Neoplasms; Oxidation-Reduction; Serine; Tumor Microenvironment; Warburg Effect, Oncologic

2021
Changes to histone modifications following prenatal alcohol exposure: An emerging picture.
    Alcohol (Fayetteville, N.Y.), 2017, Volume: 60

    Topics: Acetylation; Alcohol Drinking; Animals; Brain; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Fetal Alcohol Spectrum Disorders; Gestational Age; Histocompatibility Antigens; Histone Acetyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Maternal Exposure; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational

2017
Histone Posttranslational Modifications in Schizophrenia.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Amino Acid Sequence; Animals; Brain Chemistry; Disease Models, Animal; Electroconvulsive Therapy; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Humans; Lymphocytes; Methylation; Mice; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Schizophrenia; Ubiquitination

2017
Epigenetics of Huntington's Disease.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Animals; Cell Line; Chromatin Assembly and Disassembly; Clinical Trials as Topic; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Methylation; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Polycomb-Group Proteins; Protein Processing, Post-Translational; RNA, Untranslated

2017
Alzheimer's Disease and Histone Code Alterations.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Alzheimer Disease; Animals; Apolipoprotein E4; Brain Chemistry; Disease Models, Animal; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Mutation; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Risk Factors

2017
Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models.
    Carcinogenesis, 2017, 10-01, Volume: 38, Issue:10

    Topics: Animals; Apoptosis; CRISPR-Cas Systems; Disease Models, Animal; Epithelium; Genes, Tumor Suppressor; Humans; Intestinal Neoplasms; Methylation; Mice; Mice, Transgenic; Neoplasms, Experimental; Neoplastic Stem Cells; Oncogenes; Signal Transduction; Stem Cells

2017
Cell‑specific histone modifications in atherosclerosis (Review).
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Acetylation; Animals; Atherosclerosis; Disease Models, Animal; Histones; Humans; Methylation; Plaque, Atherosclerotic; Protein Processing, Post-Translational

2018
[Intracellularly Degradable Polyrotaxanes for Therapeutic Applications].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:2

    Topics: Animals; Autophagy; beta-Cyclodextrins; Cholesterol; Cyclodextrins; Disease Models, Animal; Drug Carriers; Drug Design; Fibroblasts; Humans; Hydrogen-Ion Concentration; Lysosomes; Macromolecular Substances; Methylation; Mice; Niemann-Pick Diseases; Poloxamer; Rotaxanes

2019
Neurodevelopmental disorders with epigenetic dysregulation and
    Frontiers in bioscience (Landmark edition), 2019, 06-01, Volume: 24, Issue:7

    Topics: Acetylation; Animals; Disease Models, Animal; Drosophila; Epigenesis, Genetic; Epigenomics; Histones; Humans; Methylation; Neurodevelopmental Disorders

2019
Histone acetylation in neurodevelopment.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Acetylation; Animals; Autistic Disorder; Disease Models, Animal; Female; Hippocampus; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Male; Methylation; Nerve Tissue Proteins; Neurogenesis; Neurons; Pregnancy; Protein Processing, Post-Translational; Teratogenesis

2013
Histone post-translational modifications to target memory-related diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Acetylation; Animals; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; Histones; Humans; Memory Disorders; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Nootropic Agents; Phosphorylation; Protein Processing, Post-Translational

2013
Histone post-translational modifications in Huntington's and Parkinson's diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Humans; Huntington Disease; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination

2013
The role of microRNAs in diabetic nephropathy.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Acetylation; Animals; Chromatin; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dogs; Epigenesis, Genetic; Epigenomics; Histones; Humans; Inflammation; Kidney; Lysine; Methylation; Mice; Mice, Transgenic; MicroRNAs; Rats

2014
Epigenetic signatures of obesity.
    The New England journal of medicine, 2015, Mar-05, Volume: 372, Issue:10

    Topics: Animals; Carbohydrates; Chromatin; Chromosomal Proteins, Non-Histone; Diet; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Male; Methylation; Mice; Obesity; Spermatozoa; Transcription, Genetic; Triglycerides

2015
Epigenetic landscape of amphetamine and methamphetamine addiction in rodents.
    Epigenetics, 2015, Volume: 10, Issue:7

    Topics: Acetylation; Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Histone Deacetylases; Histones; Humans; Methamphetamine; Methylation; Mice; Neuronal Plasticity; Proto-Oncogene Mas; Rats

2015
Recent pathogenetic advances in ANCA-associated vasculitis.
    Presse medicale (Paris, France : 1983), 2015, Volume: 44, Issue:6 Pt 2

    Topics: Alleles; Animals; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; Autoantigens; Biomarkers; Disease Models, Animal; Epigenesis, Genetic; Ethnicity; Forecasting; Genetic Predisposition to Disease; Genome-Wide Association Study; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lymphocyte Subsets; Methylation; Myeloblastin; Peroxidase; Phenotype; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational

2015
Cancer in experimental animals exposed to arsenic and arsenic compounds.
    Critical reviews in toxicology, 2010, Volume: 40, Issue:10

    Topics: Animals; Arsenic; Arsenicals; Carcinogens; Disease Models, Animal; Female; Humans; Male; Methylation; Mice; Mice, Inbred Strains; Neoplasms; Rats; Rats, Inbred Strains

2010
Folate, alcohol, and liver disease.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Absorption; Alcohol Drinking; Animals; Antioxidants; Disease Models, Animal; Epigenesis, Genetic; Ethanol; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Intestine, Small; Liver; Liver Diseases, Alcoholic; Methionine; Methylation

2013
Pleural models of inflammation: immune and nonimmune.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: Animals; Arthritis; Arthus Reaction; Calcium Pyrophosphate; Carrageenan; Cattle; Crystallization; Disease Models, Animal; Durapatite; Inflammation; Male; Methylation; Mice; Models, Animal; Pleural Effusion; Pleurisy; Rats; Rats, Wistar; Serum Albumin, Bovine; Uric Acid

2003
The assessment of inflammation, cartilage matrix, and bone loss in experimental monoarticular arthritis of the rat.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 225

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biomarkers; Bone Resorption; Cartilage, Articular; Cattle; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Immunosuppressive Agents; Inflammation; Male; Methylation; Models, Animal; Mycobacterium tuberculosis; Patella; Proteoglycans; Rats; Rats, Inbred Lew; Rats, Wistar; Rheumatic Diseases; Serum Albumin, Bovine; Species Specificity; Zymosan

2003
Folate and cancer: a review of the literature.
    Nutrition and cancer, 1994, Volume: 22, Issue:2

    Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neoplasms; Risk Factors

1994
Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects.
    Birth defects research. Part A, Clinical and molecular teratology, 2007, Volume: 79, Issue:3

    Topics: Actins; Animals; Apoptosis; Cell Cycle; Disease Models, Animal; Female; Humans; Methylation; Mice; Mice, Mutant Strains; Mutation; Neural Tube Defects; Spina Bifida Occulta

2007
The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis.
    Journal of cellular physiology, 2007, Volume: 213, Issue:3

    Topics: Acetylation; Acetyltransferases; Animals; Collagen; Disease Models, Animal; Drug Antagonism; E1A-Associated p300 Protein; Epigenesis, Genetic; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Interferon-gamma; Methylation; Mice; Models, Biological; Phosphorylation; PPAR gamma; Protein Structure, Tertiary; Smad3 Protein; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2007
5-Azacytidine and fetal hemoglobin.
    American journal of hematology, 1984, Volume: 17, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Animals; Azacitidine; Carcinogens; Disease Models, Animal; DNA; Fetal Hemoglobin; Gene Expression Regulation; Humans; Male; Methylation; Middle Aged; Papio; Thalassemia

1984
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
    Drugs, 1994, Volume: 48, Issue:2

    Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases

1994
Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion.
    Progress in clinical and biological research, 1995, Volume: 391

    Topics: Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; DNA; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Methylation; Mice

1995
Animal model for fragile X syndrome.
    Annals of medicine, 1997, Volume: 29, Issue:6

    Topics: Animals; Carrier Proteins; Codon; Cytosine; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Guanine; Humans; Intellectual Disability; Methylation; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Biosynthesis; Repetitive Sequences, Nucleic Acid; RNA-Binding Proteins; RNA, Messenger

1997
Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites.
    Toxicology and applied pharmacology, 2001, May-01, Volume: 172, Issue:3

    Topics: Animals; Arsenic; Cell Division; Disease Models, Animal; DNA Methylation; DNA Repair; Genes, p53; Growth Substances; Humans; Methylation; Mice; Mice, Transgenic; Neoplasms; Rats

2001
Genetics of neural tube defects.
    Seminars in pediatric neurology, 2001, Volume: 8, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Double-Blind Method; Female; Folic Acid; Humans; Infant, Newborn; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Placebos; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Transcription Factors; Vitamins

2001
Cobalamin deficiency and the pathogenesis of nervous system disease.
    Annual review of nutrition, 1992, Volume: 12

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Humans; Methylation; Methylmalonyl-CoA Mutase; Nervous System Diseases; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency

1992
The X chromosome in development in mouse and man.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:4

    Topics: Animals; Disease Models, Animal; Dosage Compensation, Genetic; Embryonic and Fetal Development; Female; Genetic Diseases, Inborn; Humans; Male; Methylation; Mice; Mosaicism; Sequence Homology, Nucleic Acid; X Chromosome

1992
Models of hepatocarcinogenesis in the rat--contrasts and comparisons.
    Critical reviews in toxicology, 1986, Volume: 17, Issue:1

    Topics: Animals; Animals, Newborn; Carcinogens; Diet; Disease Models, Animal; Female; Hepatectomy; Liver Neoplasms, Experimental; Methylation; Pregnancy; Rats

1986
[Experimental allergic encephalomyelitis antigen (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1974, Sep-17, Volume: 19, Issue:10

    Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cerebrospinal Fluid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Haplorhini; Immunity, Maternally-Acquired; Methylation; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Peptides; Proteins; Rats; Species Specificity

1974

Trials

1 trial(s) available for isomethyleugenol and Disease Models, Animal

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023

Other Studies

264 other study(ies) available for isomethyleugenol and Disease Models, Animal

ArticleYear
CircRNA MFACR Is Upregulated in Myocardial Infarction and Downregulates miR-125b to Promote Cardiomyocyte Apoptosis Induced by Hypoxia.
    Journal of cardiovascular pharmacology, 2021, 09-12, Volume: 78, Issue:6

    Topics: Animals; Apoptosis; Case-Control Studies; Cell Hypoxia; Cell Line; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Male; Methylation; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Myocardial Infarction; Myocytes, Cardiac; RNA Processing, Post-Transcriptional; RNA, Circular; Signal Transduction

2021
Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery.
    Molecular brain, 2021, 09-20, Volume: 14, Issue:1

    Topics: Animals; Annexins; Benzazepines; Cornified Envelope Proline-Rich Proteins; Disease Models, Animal; Electrocoagulation; Female; Foot Injuries; Gene Expression Regulation; Gene Knock-In Techniques; Genes, fos; Genes, Reporter; Histone Code; Histones; Hyperalgesia; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuralgia; Neurons; Pain, Postoperative; Pyrimidines; RNA, Messenger; Spinal Cord; Tamoxifen

2021
PPAR-α Hypermethylation in the Hippocampus of Mice Exposed to Social Isolation Stress Is Associated with Enhanced Neuroinflammation and Aggressive Behavior.
    International journal of molecular sciences, 2021, Oct-01, Volume: 22, Issue:19

    Topics: Aggression; Animals; Behavior, Animal; Chromatin Assembly and Disassembly; CpG Islands; Disease Models, Animal; Disease Susceptibility; Epigenesis, Genetic; Gene Expression; Hippocampus; Inflammation; Inflammation Mediators; Male; Methylation; Mice; PPAR alpha; Promoter Regions, Genetic; Signal Transduction; Social Isolation; Stress, Psychological

2021
m6A regulator-mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in severe asthma.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:21

    Topics: Adenosine; Animals; Asthma; Biomarkers; Cellular Microenvironment; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Methylation; Mice; Models, Biological; RNA, Messenger; ROC Curve; Severity of Illness Index; Transcriptome

2021
METTL3-mediated m
    Annals of the rheumatic diseases, 2022, Volume: 81, Issue:1

    Topics: Adenosine; Animals; Autophagy; Autophagy-Related Protein 7; Cartilage, Articular; Cell Line; Cellular Senescence; Chondrocytes; Coculture Techniques; Disease Models, Animal; Disease Progression; Female; GATA4 Transcription Factor; Gene Expression; Humans; Immunoprecipitation; Male; Methylation; Methyltransferases; Mice; Middle Aged; Osteoarthritis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Synoviocytes; Up-Regulation

2022
Alteration of the m
    Epigenomics, 2021, Volume: 13, Issue:23

    Topics: Adenosine; Animals; Autoimmune Diseases; Bleomycin; Connective Tissue Diseases; Disease Models, Animal; Female; Fibrosis; Gene Expression; Methylation; Mice, Inbred BALB C; RNA, Messenger; Skin

2021
Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice.
    Nature communications, 2021, 11-26, Volume: 12, Issue:1

    Topics: Adenosine; Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Case-Control Studies; Depressive Disorder, Major; Disease Models, Animal; Down-Regulation; Female; Gene Knockdown Techniques; Healthy Volunteers; Hippocampus; Humans; Male; Methylation; Mice; Mice, Knockout; Middle Aged; Receptors, Adrenergic, beta-2; Young Adult

2021
Induction of m
    Journal of experimental & clinical cancer research : CR, 2022, Jan-03, Volume: 41, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Resistance, Neoplasm; Exosomes; Humans; Membrane Glycoproteins; Methylation; Mice; Mice, Knockout; Multiple Myeloma; Nerve Tissue Proteins; RNA, Long Noncoding; Signal Transduction; Tumor Microenvironment; Up-Regulation

2022
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation.
    Bioengineered, 2022, Volume: 13, Issue:2

    Topics: Animals; CD40 Ligand; Disease Models, Animal; Female; Hydroxybutyrate Dehydrogenase; Lupus Erythematosus, Systemic; Methylation; Mice; Mice, Inbred BALB C; Th1 Cells; Th2 Cells

2022
CircMET promotes tumor proliferation by enhancing CDKN2A mRNA decay and upregulating SMAD3.
    Molecular cancer, 2022, 01-18, Volume: 21, Issue:1

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Proliferation; Chromatin Immunoprecipitation Sequencing; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Methylation; Mice; Models, Biological; Protein Binding; Proto-Oncogene Proteins c-met; RNA Processing, Post-Transcriptional; RNA Stability; RNA Transport; RNA, Circular; RNA, Messenger; Smad3 Protein; Translocation, Genetic

2022
Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.
    Clinical and translational medicine, 2022, Volume: 12, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; China; Disease Models, Animal; Glycolysis; Histology; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Methylation; Mice; Protein-Arginine N-Methyltransferases

2022
Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys.
    Scientific reports, 2022, 01-31, Volume: 12, Issue:1

    Topics: Acute Kidney Injury; Adenosine; Animals; Cell Line; Disease Models, Animal; Extracellular Vesicles; Ischemia; Kidney; Methylation; Mice; Oxidative Stress; Rats, Sprague-Dawley; Repressor Proteins; RNA, Transfer; Transcription, Genetic

2022
Kynurenic Acid and Its Analog SZR104 Exhibit Strong Antiinflammatory Effects and Alter the Intracellular Distribution and Methylation Patterns of H3 Histones in Immunochallenged Microglia-Enriched Cultures of Newborn Rat Brains.
    International journal of molecular sciences, 2022, Jan-19, Volume: 23, Issue:3

    Topics: Amides; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cells, Cultured; Chemokine CXCL10; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Kynurenic Acid; Lipopolysaccharides; Male; Methylation; Microglia; Pregnancy; Rats; Receptors, CCR1

2022
Inhibition of A2AR gene methylation alleviates white matter lesions in chronic cerebral hypoperfusion rats.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:8

    Topics: Animals; Brain Ischemia; Cognitive Dysfunction; Disease Models, Animal; Maze Learning; Methylation; Rats; Rats, Sprague-Dawley; White Matter

2022
METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma.
    The Journal of clinical investigation, 2022, 11-01, Volume: 132, Issue:21

    Topics: Animals; Disease Models, Animal; Glaucoma; Histones; Intraocular Pressure; Methylation; Mice; Mutation; Retinal Ganglion Cells

2022
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
    Apoptosis : an international journal on programmed cell death, 2023, Volume: 28, Issue:1-2

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Methylation; RNA Splicing Factors; RNA, Messenger; RNA, Small Interfering

2023
Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease.
    Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 3

    Topics: Animals; Disease Models, Animal; Humans; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polychlorinated Biphenyls; RNA, Messenger

2023
Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic.
    Cells, 2022, 10-31, Volume: 11, Issue:21

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; DNA; DNA Methylation; Humans; Methylation; Methyltransferases; Mice; Mice, Transgenic; Muscle, Skeletal; RNA; RNA Processing, Post-Transcriptional; Superoxide Dismutase; Superoxide Dismutase-1

2022
EZH2 Promotes Cholangiocarcinoma Development and Progression through Histone Methylation and microRNA-Mediated Down-Regulation of Tumor Suppressor Genes.
    The American journal of pathology, 2022, Volume: 192, Issue:12

    Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Genes, Tumor Suppressor; Histones; Humans; Methylation; Mice; MicroRNAs

2022
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma.
    Nature communications, 2023, 02-23, Volume: 14, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Humans; Liver Neoplasms; Methylation; Phosphoglycerate Dehydrogenase; Protein-Arginine N-Methyltransferases; Repressor Proteins; Serine

2023
METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
    Biochemical and biophysical research communications, 2019, 10-08, Volume: 518, Issue:1

    Topics: Adenosine; Animals; Dependovirus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acid Synthase, Type I; Fatty Acids; Gene Deletion; Glucose; Hepatocytes; Homeostasis; Humans; Insulin Resistance; Liver; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Knockout; Obesity; RNA, Messenger

2019
Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil.
    Scientific reports, 2019, 08-20, Volume: 9, Issue:1

    Topics: Acetylation; Animals; Cell Death; Dendritic Spines; Dentate Gyrus; Disease Models, Animal; Donepezil; Doublecortin Protein; Epigenesis, Genetic; Ethanol; Hippocampus; Humans; Inflammation; Methylation; Neurogenesis; Rats; Underage Drinking

2019
Effect of SOD2 methylation on mitochondrial DNA4834-bp deletion mutation in marginal cells under oxidative stress.
    Bosnian journal of basic medical sciences, 2020, Feb-05, Volume: 20, Issue:1

    Topics: Animals; Cell Culture Techniques; Disease Models, Animal; DNA, Mitochondrial; Ear, Inner; Hydrogen Peroxide; Methylation; Oxidative Stress; Presbycusis; Rats; Rats, Wistar; Sequence Deletion; Superoxide Dismutase

2020
Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease.
    Journal of immunology (Baltimore, Md. : 1950), 2019, 12-01, Volume: 203, Issue:11

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; Colitis; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Lipopolysaccharides; Macrophages; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases

2019
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
    Nature cell biology, 2019, Volume: 21, Issue:11

    Topics: Animals; Bone Marrow Transplantation; Cell Lineage; Disease Models, Animal; Doxycycline; Epigenesis, Genetic; Erythroid Cells; Female; Granulocytes; Histones; Leukemia, T-Cell; Lysine; Male; Methionine; Methylation; Mice; Mice, Transgenic; Mouse Embryonic Stem Cells; Mutation; Signal Transduction; Survival Analysis; T-Lymphocytes; Teratoma

2019
Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation.
    Cellular & molecular immunology, 2020, Volume: 17, Issue:5

    Topics: Adolescent; Adult; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Bone Marrow; Bone Marrow Transplantation; Child; Disease Models, Animal; Down-Regulation; Female; Forkhead Transcription Factors; Gene Deletion; Gene Expression Profiling; Graft vs Host Disease; Humans; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Protein Serine-Threonine Kinases; T-Lymphocytes, Regulatory; Transcription, Genetic

2020
SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish.
    Stem cell research & therapy, 2019, 12-16, Volume: 10, Issue:1

    Topics: Animals; Cell Differentiation; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; Histones; Methylation; Neural Stem Cells; Neural Tube; Prosencephalon; SOX Transcription Factors; Zebrafish; Zebrafish Proteins

2019
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
    Molecular cancer, 2019, 12-19, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays

2019
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
    Cell metabolism, 2020, 02-04, Volume: 31, Issue:2

    Topics: Animals; Cell Proliferation; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Methionine; Methylation; Mice, Inbred C57BL; Mice, Knockout; Multiple Sclerosis; Th17 Cells

2020
Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway.
    Scientific reports, 2020, 02-27, Volume: 10, Issue:1

    Topics: Aging; Animals; Disease Models, Animal; DNA-Binding Proteins; Female; Hematopoietic Stem Cells; Histones; Humans; Hypercholesterolemia; Male; Methylation; Mice; Mice, Knockout; Phenotype; Proto-Oncogene Proteins

2020
Epigenetic Regulation of
    International journal of molecular sciences, 2020, Mar-10, Volume: 21, Issue:5

    Topics: Acetylation; Animals; Brain Injuries, Traumatic; Chromatin Immunoprecipitation; Disease Models, Animal; Enhancer Elements, Genetic; Epigenesis, Genetic; Histones; Methylation; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Regeneration; Wnt3A Protein

2020
The effect of folic acid deficiency on Mest/Peg1 in neural tube defects.
    The International journal of neuroscience, 2021, Volume: 131, Issue:5

    Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Female; Fetus; Folic Acid Deficiency; Gene Expression Regulation; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Methylation; Mice; Mice, Inbred C57BL; Neural Tube Defects; Proteins; Wnt Signaling Pathway

2021
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
    Nature communications, 2020, 04-24, Volume: 11, Issue:1

    Topics: Animals; Bacterial Adhesion; Cell Line; Disease Models, Animal; Epithelial Cells; Flagella; Flagellin; Histone-Lysine N-Methyltransferase; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Methylation; Mice; NIH 3T3 Cells; Protein Processing, Post-Translational; Salmonella Infections; Salmonella typhimurium

2020
Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter.
    EBioMedicine, 2020, Volume: 55

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Base Sequence; Biological Transport; CCCTC-Binding Factor; Cholesterol; Cyclin-Dependent Kinase Inhibitor p15; Disease Models, Animal; DNA; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Foam Cells; Histones; Humans; Lipid Metabolism; Methylation; Mice; Mice, Knockout; Plaque, Atherosclerotic; Primary Cell Culture; Promoter Regions, Genetic; RNA, Long Noncoding; THP-1 Cells

2020
Long noncoding RNA ANRIL promotes the malignant progression of cholangiocarcinoma by epigenetically repressing ERRFI1 expression.
    Cancer science, 2020, Volume: 111, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cholangiocarcinoma; Disease Models, Animal; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins

2020
Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses.
    Cells, 2020, 05-14, Volume: 9, Issue:5

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Cell Line, Tumor; Disease Models, Animal; HEK293 Cells; Humans; Inflammation; Macrophage Activation; Macrophages; Male; MAP Kinase Signaling System; Methylation; Mice; Models, Biological; Myeloid Differentiation Factor 88; Protein Methyltransferases; ras Proteins; RAW 264.7 Cells; Substrate Specificity; Toll-Like Receptors; Transcription Factor AP-1

2020
Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.
    PLoS genetics, 2020, Volume: 16, Issue:5

    Topics: Animals; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Knockout Techniques; Histones; Liver; Liver Cirrhosis; Male; Methylation; Mice; Polycomb Repressive Complex 2; Sequence Analysis, RNA; Sex Characteristics

2020
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation.
    Communications biology, 2020, 06-01, Volume: 3, Issue:1

    Topics: Abnormalities, Multiple; Aggression; Animals; Craniofacial Abnormalities; Dendritic Spines; Disease Models, Animal; Growth Disorders; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Hypertrichosis; Intellectual Disability; Male; Mental Retardation, X-Linked; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein

2020
m
    Immunity, 2020, 06-16, Volume: 52, Issue:6

    Topics: Adenosine; Animals; Biomarkers; Bone Marrow Failure Disorders; Cell Differentiation; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Hematopoiesis; Hematopoietic Stem Cells; Immunity, Innate; Immunophenotyping; Methylation; Methyltransferases; Mice; Mice, Knockout; RNA, Double-Stranded

2020
MicroRNA-200a Inhibits Inflammation and Atherosclerotic Lesion Formation by Disrupting EZH2-Mediated Methylation of STAT3.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Apoptosis; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipoproteins, LDL; Lysine; Male; Methylation; Mice, Knockout, ApoE; MicroRNAs; Phosphorylation; Plaque, Atherosclerotic; Signal Transduction; STAT3 Transcription Factor

2020
Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin.
    Pharmacological research, 2020, Volume: 161

    Topics: Animals; Arginine; beta Catenin; Cells, Cultured; Disease Models, Animal; Epigenesis, Genetic; Histones; Hypertrophy, Left Ventricular; Male; Methylation; Mice, Inbred C57BL; Myocytes, Cardiac; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling

2020
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
    International journal of biological macromolecules, 2020, Oct-15, Volume: 161

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Cell Survival; Cholesterol; Cornus; Disease Models, Animal; Foam Cells; Glucans; Immunohistochemistry; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Methylation; Mice; Mice, Knockout; Molecular Weight; Monosaccharides; Plant Extracts; Plaque, Atherosclerotic; RAW 264.7 Cells; Spectrum Analysis; Structure-Activity Relationship

2020
β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer.
    Molecular cancer, 2020, 08-24, Volume: 19, Issue:1

    Topics: Adenosine; Animals; Apoptosis; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; Humans; Methylation; Mice; MicroRNAs; Models, Biological; Protein Biosynthesis; RNA Interference; RNA, Messenger; Xenograft Model Antitumor Assays

2020
Upregulation of METTL14 mediates the elevation of PERP mRNA N
    Molecular cancer, 2020, 08-25, Volume: 19, Issue:1

    Topics: Adenine; Animals; Binding Sites; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Heterografts; Humans; Kaplan-Meier Estimate; Membrane Proteins; Methylation; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Protein Binding; RNA Stability; RNA, Messenger

2020
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N
    Nature cell biology, 2020, Volume: 22, Issue:11

    Topics: Adenosine; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3 beta; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NFATC Transcription Factors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; RNA Stability; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling

2020
Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing.
    PLoS genetics, 2020, Volume: 16, Issue:10

    Topics: Alternative Splicing; Animals; Brain; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Humans; Methyl-CpG-Binding Protein 2; Methylation; Mice; Mice, Knockout; Mutation; Neurons; Protein Binding; Rett Syndrome; Transcriptome

2020
DM-induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:24

    Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Susceptibility; Gene Expression; Gene Knockdown Techniques; Histamine; Immunoglobulin E; Inflammation Mediators; Insulin; Mast Cells; Methylation; Rats; Receptor, IGF Type 1; Receptor, Insulin

2020
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
    Nature communications, 2020, 12-04, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methylation; Mice, Knockout; Proto-Oncogene Proteins c-myc; ras Proteins; Tumor Suppressor Protein p53

2020
The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice.
    Aging, 2020, 12-28, Volume: 13, Issue:2

    Topics: Acetylation; Animals; Brain; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Dwarfism, Pituitary; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Growth Hormone; Histone Code; Histones; Homeodomain Proteins; Hormone Replacement Therapy; Intra-Abdominal Fat; Liver; Longevity; Methylation; Mice; Subcutaneous Fat

2020
A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice.
    Theranostics, 2021, Volume: 11, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetylation; Animals; Ataxia; Brain; Brain Injuries, Traumatic; Diet, Ketogenic; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Disease Models, Animal; Docosahexaenoic Acids; Epigenesis, Genetic; Glycemic Index; Histone Code; Inflammation; Lameness, Animal; Leucine; Male; Methylation; Mice; Morris Water Maze Test; Oligodendroglia; Paresis; Postural Balance; Rotarod Performance Test; Sensation Disorders; Signal Transduction; Spatial Memory; TOR Serine-Threonine Kinases; Triglycerides

2021
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease.
    Genome biology, 2021, 01-05, Volume: 22, Issue:1

    Topics: Adenosine; Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Humans; Methylation; Methyltransferases; Mice; Neurodegenerative Diseases; RNA Stability

2021
BCL-6 promotes the methylation of miR-34a by recruiting EZH2 and upregulating CTRP9 to protect ischemic myocardial injury.
    BioFactors (Oxford, England), 2021, Volume: 47, Issue:3

    Topics: Adiponectin; Animals; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Glycoproteins; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Proto-Oncogene Proteins c-bcl-6; Signal Transduction; Up-Regulation

2021
Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific
    Gut, 2022, Volume: 71, Issue:1

    Topics: Adenosine; Animals; Celiac Disease; Cell Line; Disease Models, Animal; Epithelial Cells; Exportin 1 Protein; HLA-DQ Antigens; Humans; Intestinal Mucosa; Karyopherins; Methylation; Mice, Knockout; NF-kappa B; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear; RNA

2022
The UFSP2/UFMylation Pathway Is Involved in Silica-Induced Pulmonary Injury.
    DNA and cell biology, 2021, Volume: 40, Issue:4

    Topics: Animals; China; Cysteine Endopeptidases; Disease Models, Animal; Epithelial-Mesenchymal Transition; Lung; Lung Injury; Male; Methylation; Mice; Mice, Inbred C57BL; Proteins; Pulmonary Fibrosis; Silicon Dioxide; Silicosis

2021
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
    Cell reports, 2021, 04-13, Volume: 35, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Axonal Transport; Brain-Derived Neurotrophic Factor; Cell Death; Disease Models, Animal; Drosophila melanogaster; Epigenesis, Genetic; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neuromuscular Junction; Neurons; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Transport Vesicles

2021
The role of RNA m
    Respiratory research, 2021, Apr-26, Volume: 22, Issue:1

    Topics: Adenine; Animals; Animals, Newborn; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Male; Methylation; Methyltransferases; Pulmonary Artery; Rats, Sprague-Dawley; RNA; RNA Processing, Post-Transcriptional; Time Factors; Vascular Remodeling; Ventricular Function, Right; Ventricular Pressure

2021
Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dogs; Humans; Lymphoma, Non-Hodgkin; Methylation; Protein-Arginine N-Methyltransferases

2021
Calcitonin gene-related peptide regulates spinal microglial activation through the histone H3 lysine 27 trimethylation via enhancer of zeste homolog-2 in rats with neuropathic pain.
    Journal of neuroinflammation, 2021, May-21, Volume: 18, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Expression; Histones; Indoles; Inflammation; Male; Methylation; Microglia; Neuralgia; Nociceptors; Peptide Fragments; Peripheral Nerve Injuries; Pyridones; Rats; Rats, Wistar; Signal Transduction; Spinal Cord

2021
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
    Biological research, 2021, Aug-06, Volume: 54, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; Methylation; Mice; PPAR alpha; Promoter Regions, Genetic; Retina

2021
Interaction of tau with HNRNPA2B1 and N
    Molecular cell, 2021, 10-21, Volume: 81, Issue:20

    Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Case-Control Studies; Cerebral Cortex; Disease Models, Animal; Disease Progression; Female; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Aggregates; Protein Aggregation, Pathological; RNA; RNA Processing, Post-Transcriptional; Severity of Illness Index; tau Proteins

2021
Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence.
    Alcohol (Fayetteville, N.Y.), 2017, Volume: 60

    Topics: Acetylation; Alcohol Abstinence; Alcohol Withdrawal Seizures; Alcoholism; Animals; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Ethanol; Gene Expression Regulation, Enzymologic; Gene Regulatory Networks; Histone-Lysine N-Methyltransferase; Histones; Inhalation Exposure; Intracellular Signaling Peptides and Proteins; Male; Methylation; Mice; Prefrontal Cortex; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Time Factors; Ubiquitination

2017
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
    Journal of medicinal chemistry, 2017, 05-25, Volume: 60, Issue:10

    Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Halogenation; Humans; Lung; Lung Diseases; Male; Methylation; Mice, Inbred C57BL; Models, Molecular; Pyridines; Structure-Activity Relationship

2017
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Dealkylation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Methylation; Mice; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Xenograft Model Antitumor Assays

2017
Changes in the content of fatty acids in CA1 and CA3 areas of the hippocampus of Krushinsky-Molodkina rats after single and fivefold audiogenic seizures.
    Epilepsy research, 2017, Volume: 135

    Topics: Acoustic Stimulation; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromatography, Gas; Disease Models, Animal; Fatty Acids; Male; Methylation; Rats; Seizures

2017
m
    Nature, 2017, 08-17, Volume: 548, Issue:7667

    Topics: Adenosine; Adoptive Transfer; Animals; Cell Differentiation; Cell Proliferation; Colitis; Disease Models, Animal; DNA-Binding Proteins; Female; Homeostasis; Interleukin-7; Male; Methylation; Methyltransferases; Mice; RNA Stability; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes

2017
Involvement of Cryptosporidium parvum Cdg7_FLc_1000 RNA in the Attenuation of Intestinal Epithelial Cell Migration via Trans-Suppression of Host Cell SMPD3.
    The Journal of infectious diseases, 2017, 12-27, Volume: 217, Issue:1

    Topics: Animals; Cell Line; Cell Movement; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Epithelial Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Intestinal Diseases; Methylation; Mice; Protein Processing, Post-Translational; RNA, Protozoan; Sphingomyelin Phosphodiesterase

2017
Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:1

    Topics: Animals; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Liver Neoplasms; Methylation; Mice; Mice, Nude; Protein Binding; Proteins; Proto-Oncogene Proteins; RNA-Binding Proteins; Transcription Factors

2018
Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Coffee; Cognition; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Electrophysiology; Fear; Female; Long-Term Potentiation; Male; Maze Learning; Methylation; Mice; Mice, Inbred C57BL; Nervous System Diseases; Neuronal Plasticity; Phosphorylation; Serotonin; Solubility

2017
EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis.
    Journal of experimental & clinical cancer research : CR, 2018, Jan-09, Volume: 37, Issue:1

    Topics: 3' Untranslated Regions; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Female; Galectins; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Interferon-gamma; Liver Neoplasms; Methylation; Mice; MicroRNAs; Promoter Regions, Genetic; RNA Interference

2018
Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.
    eLife, 2018, 01-31, Volume: 7

    Topics: Animals; Antigens, Neoplasm; Casein Kinase II; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Methylation; Mice; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; SKP Cullin F-Box Protein Ligases; Stomach Neoplasms; Ubiquitination

2018
Biochemical validation of EHMT1 missense mutations in Kleefstra syndrome.
    Journal of human genetics, 2018, Volume: 63, Issue:5

    Topics: Amino Acid Substitution; Animals; Chromosome Deletion; Chromosomes, Human, Pair 9; Craniofacial Abnormalities; Disease Models, Animal; Embryonic Stem Cells; Female; Heart Defects, Congenital; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Intellectual Disability; Methylation; Mice; Mice, Knockout; Models, Molecular; Mutation, Missense; Protein Binding; Protein Conformation; Protein Multimerization; Structure-Activity Relationship

2018
DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.
    Cell death & disease, 2018, 02-22, Volume: 9, Issue:3

    Topics: Adenosine; Amino Acid Motifs; Animals; Calpain; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Male; Methylation; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Retina; Retinal Degeneration

2018
Erythropoietin Upregulates Brain Hemoglobin Expression and Supports Neuronal Mitochondrial Activity.
    Molecular neurobiology, 2018, Volume: 55, Issue:10

    Topics: Animals; Aspartic Acid; Brain; Cell Respiration; Cuprizone; Disease Models, Animal; Electron Transport Complex III; Erythropoietin; Hemoglobins; Histones; Lysine; Male; Methylation; Mice, Inbred C57BL; Mitochondria; Models, Biological; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Neurons; Up-Regulation

2018
Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.
    Nucleic acids research, 2018, 06-01, Volume: 46, Issue:10

    Topics: Animals; Animals, Newborn; Cadherins; Chromosome Deletion; Chromosomes, Human, Pair 9; Cognitive Dysfunction; Craniofacial Abnormalities; Disease Models, Animal; Gene Expression Regulation; Heart Defects, Congenital; Hippocampus; Histone-Lysine N-Methyltransferase; Histones; Intellectual Disability; Lysine; Male; Methylation; Mice, Knockout

2018
CTLA-4 methylation regulates the pathogenesis of myasthenia gravis and the expression of related cytokines.
    Medicine, 2018, Volume: 97, Issue:18

    Topics: Acetylcholinesterase; Adolescent; Adult; Aged; Animals; Child; CTLA-4 Antigen; Cytokines; Disease Models, Animal; Female; Humans; Male; Methylation; Middle Aged; Myasthenia Gravis; Rats, Inbred Lew; T-Lymphocytes, Regulatory; Up-Regulation; Young Adult

2018
Enhancer of zeste homolog 2-catalysed H3K27 trimethylation plays a key role in acute-on-chronic liver failure via TNF-mediated pathway.
    Cell death & disease, 2018, 05-22, Volume: 9, Issue:6

    Topics: Acute-On-Chronic Liver Failure; Animals; Biocatalysis; Chromatin; Cytokines; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Indoles; Inflammation Mediators; Kupffer Cells; Lipopolysaccharides; Liver; Lysine; Methylation; Mice, Inbred C57BL; NF-kappa B; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyridones; Signal Transduction; Tumor Necrosis Factor-alpha

2018
Study on the Structure of Ginseng Glycopeptides with Anti-Inflammatory and Analgesic Activity.
    Molecules (Basel, Switzerland), 2018, May-31, Volume: 23, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Glycopeptides; Inflammation Mediators; Male; Methylation; Molecular Structure; Pain; Pain Management; Panax; Rats; Structure-Activity Relationship; Tandem Mass Spectrometry

2018
X chromosome protects against bladder cancer in females via a
    Science advances, 2018, Volume: 4, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, X-Linked; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Histone Demethylases; Methylation; Mice; Mice, Knockout; Mutation; Prognosis; Sex Chromosomes; Sex Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; X Chromosome

2018
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.
    Journal of virology, 2018, 09-01, Volume: 92, Issue:17

    Topics: Aging; Animals; Archaeal Proteins; Chlorocebus aethiops; Coronavirus; Coronavirus Infections; Disease Models, Animal; Immunocompromised Host; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mutation; Severe acute respiratory syndrome-related coronavirus; Vaccines, Attenuated; Vero Cells; Viral Nonstructural Proteins; Viral Vaccines; Virus Replication

2018
Inhibition of H3K27me3 demethylases attenuates asthma by reversing the shift in airway smooth muscle phenotype.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2018, Volume: 48, Issue:11

    Topics: Airway Remodeling; Allergens; Animals; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Histone Demethylases; Humans; Methylation; Mice; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myocytes, Smooth Muscle; Phenotype; Proto-Oncogene Proteins c-akt; Signal Transduction

2018
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 12-15, Volume: 24, Issue:24

    Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Gene Knockdown Techniques; Glutarates; Histones; Humans; Kidney Neoplasms; Methylation; Molecular Targeted Therapy; Phenotype; RNA, Small Interfering; Xenograft Model Antitumor Assays

2018
Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival.
    Theranostics, 2018, Volume: 8, Issue:16

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Gene Expression Profiling; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice, Transgenic; Myeloid Cells; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Proto-Oncogene Proteins

2018
Arginine methylation of FOXP3 is crucial for the suppressive function of regulatory T cells.
    Journal of autoimmunity, 2019, Volume: 97

    Topics: Animals; Arginine; Biomarkers; Cell Line; Cytokines; Disease Models, Animal; Fluorescent Antibody Technique; Forkhead Transcription Factors; Gene Expression Profiling; Graft vs Host Disease; Humans; Kaplan-Meier Estimate; Male; Methylation; Mice; Mutation; Protein Processing, Post-Translational; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory

2019
Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Adenosine; Animals; Benzamides; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histone Code; Histones; Humans; Indoles; Methylation; Mice; Morpholines; Pyridones; T-Lymphocytes

2018
Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Male; Methylation; Neurons; Parvalbumins; Prefrontal Cortex; Rats; Rats, Wistar; Schizophrenia; Social Isolation

2019
Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control.
    Molecular and cellular endocrinology, 2019, 02-05, Volume: 481

    Topics: Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Epigenesis, Genetic; Glucose Transporter Type 4; Histones; Humans; Insulin; Lysine; Male; Methylation; Mice; Muscle, Skeletal; Promoter Regions, Genetic; Rats; Resveratrol

2019
m
    Nature immunology, 2019, Volume: 20, Issue:2

    Topics: Adenosine; Animals; Cell Line, Tumor; Cytomegalovirus; Disease Models, Animal; Female; Fibroblasts; Herpesviridae Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferon Type I; Male; Methylation; Methyltransferases; Mice; Mice, Inbred ICR; Mice, Knockout; Muromegalovirus; RNA-Binding Proteins; RNA, Messenger

2019
Structure characterization of low molecular weight sulfate Ulva polysaccharide and the effect of its derivative on iron deficiency anemia.
    International journal of biological macromolecules, 2019, Apr-01, Volume: 126

    Topics: Anemia, Iron-Deficiency; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Hemoglobins; Iron; Male; Methylation; Molecular Weight; Monosaccharides; Particle Size; Polysaccharides; Rats, Wistar; Reference Standards; Spectroscopy, Fourier Transform Infrared; Sulfates; Transferrin; Ulva; Weight Gain

2019
Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila.
    Nature communications, 2019, 01-14, Volume: 10, Issue:1

    Topics: Animals; Animals, Genetically Modified; Cardiomyopathies; Diet, High-Fat; Disease Models, Animal; Drosophila; Drosophila Proteins; Female; Genetic Predisposition to Disease; Histones; Humans; Lipase; Lipid Metabolism; Male; Methylation; Myocardium; Obesity; Positive Transcriptional Elongation Factor B; Triglycerides

2019
Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Adenosine; AIDS Dementia Complex; Animals; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation; Hippocampus; HIV-1; Host-Pathogen Interactions; Humans; Male; Methylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; RNA Splicing; RNA, Messenger; RNA, Viral; Sequence Analysis, RNA; Transcriptome

2019
Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice.
    Molecular psychiatry, 2020, Volume: 25, Issue:10

    Topics: Animals; Autistic Disorder; Disease Models, Animal; Female; Haploinsufficiency; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Mice; Microfilament Proteins; Nerve Tissue Proteins; Prefrontal Cortex; Quinazolines

2020
Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer's disease.
    Brain : a journal of neurology, 2019, 03-01, Volume: 142, Issue:3

    Topics: Alzheimer Disease; Animals; Chromosome Deletion; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hippocampus; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Memory Disorders; Methylation; Mice; Mice, Transgenic; Prefrontal Cortex; Synapses

2019
Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy.
    Scientific reports, 2019, 01-22, Volume: 9, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain Diseases; Brain Edema; Caveolin 1; Cytokines; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Interferon Type I; Lipopolysaccharides; Methylation; Mice; Orthomyxoviridae; Orthomyxoviridae Infections

2019
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 02-26, Volume: 116, Issue:9

    Topics: Animals; Bleomycin; Cell Movement; Disease Models, Animal; Endothelial Cells; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Mice; Microfilament Proteins; Neovascularization, Physiologic; Receptors, Notch; Scleroderma, Diffuse; Signal Transduction

2019
Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.
    European journal of nutrition, 2020, Volume: 59, Issue:2

    Topics: Acetylation; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Humans; Isothiocyanates; Lysine; Melanoma; Methylation; Mice

2020
An augmentation in histone dimethylation at lysine nine residues elicits vision impairment following traumatic brain injury.
    Free radical biology & medicine, 2019, Volume: 134

    Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Histones; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Myelin Sheath; NF-E2-Related Factor 2; Optic Nerve; Oxidative Stress; Retinal Ganglion Cells; Vision Disorders

2019
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
    International journal of molecular sciences, 2019, Feb-23, Volume: 20, Issue:4

    Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12

2019
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death.
    ACS chemical neuroscience, 2019, 05-15, Volume: 10, Issue:5

    Topics: Adenosine; Animals; Apoptosis; Brain; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Epigenesis, Genetic; Male; Methylation; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympatholytics

2019
Respiratory syncytial virus promoted the differentiation of Th17 cells in airway microenvironment through activation of Notch-1/Delta3.
    Journal of medical microbiology, 2019, Volume: 68, Issue:4

    Topics: AIRE Protein; Animals; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cellular Microenvironment; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Jagged-1 Protein; Lung; Male; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Receptor, Notch1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Th1 Cells; Th17 Cells; Transcription Factors

2019
Epigenetic regulation of phosphodiesterase 4d in restrictive cardiomyopathy mice with cTnI mutations.
    Science China. Life sciences, 2020, Volume: 63, Issue:4

    Topics: Acetylation; Animals; Cardiomyopathy, Restrictive; Cell Nucleus; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; DNA-Binding Proteins; Epigenesis, Genetic; Heart; Histone Deacetylase 1; Histones; Lysine; Methylation; Mice; Muscle Proteins; Mutation; Myocytes, Cardiac; Promoter Regions, Genetic; Transcription Factors; Troponin I

2020
Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.
    Journal of autoimmunity, 2019, Volume: 101

    Topics: Animals; Autoimmunity; Cell Line; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Gene Regulatory Networks; Male; Methylation; Mice; Mice, Knockout; Models, Molecular; Multiple Sclerosis; Neurons; Signal Transduction; Structure-Activity Relationship; Synapses; T-Lymphocyte Subsets; tau Proteins; Transcription, Genetic

2019
Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of α‑synuclein methylation.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: alpha-Synuclein; Animals; Behavior, Animal; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Introns; Lithium; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; MPTP Poisoning; Neuroprotective Agents; Substantia Nigra

2019
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
    Science translational medicine, 2019, 05-29, Volume: 11, Issue:494

    Topics: Adipocytes; Adipokines; Animals; Bone Diseases; Bone Marrow; Bone Resorption; Cell Line, Tumor; Cellular Reprogramming; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Methylation; Mice; Multiple Myeloma; Osteoblasts; Osteogenesis; Polycomb Repressive Complex 2; PPAR gamma; Promoter Regions, Genetic; Remission Induction; Signal Transduction; Sp1 Transcription Factor; Up-Regulation

2019
Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-07, Volume: 38, Issue:1

    Topics: Adult; Animals; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Senescence; Disease Models, Animal; Female; Gallbladder Neoplasms; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; Middle Aged; Models, Biological; Prognosis; RNA Interference; RNA, Long Noncoding; Young Adult

2019
Control of Hematopoietic Stem and Progenitor Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity.
    Stem cell reports, 2019, 07-09, Volume: 13, Issue:1

    Topics: Anemia; Animals; Disease Models, Animal; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation; Genome; Hematopoiesis; Hematopoietic Stem Cells; Histones; Humans; Methylation; Mice; Mice, Knockout; Models, Molecular; Oxygen Consumption; Phenotype; Pyruvate Kinase; Resting Phase, Cell Cycle; Transcription Factors

2019
Position-dependent correlation between TBX22 exon 5 methylation and palatal shelf fusion in the development of cleft palate.
    Anais da Academia Brasileira de Ciencias, 2019, Jun-19, Volume: 91, Issue:2

    Topics: Animals; Cleft Palate; Disease Models, Animal; Embryonic Development; Exons; Female; Genetic Diseases, X-Linked; Methylation; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy; T-Box Domain Proteins

2019
Profiling histone modifications in the normal mouse kidney and after unilateral ureteric obstruction.
    American journal of physiology. Renal physiology, 2019, 09-01, Volume: 317, Issue:3

    Topics: Acetylation; Animals; Biomarkers; Disease Models, Animal; Gene Expression Regulation; Histones; Kidney; Kidney Diseases; Male; Mass Spectrometry; Methylation; Mice, Inbred C57BL; Protein Processing, Post-Translational; Proteomics; Transcription, Genetic; Ureteral Obstruction

2019
Epitranscriptomic mechanisms of N6-methyladenosine methylation regulating mammalian hypertension development by determined spontaneously hypertensive rats pericytes.
    Epigenomics, 2019, Volume: 11, Issue:12

    Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adenosine; Animals; Disease Models, Animal; Epigenomics; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Hypertension; Male; Methylation; Organ Specificity; Pericytes; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2019
Premature impairment of methylation pathway and cardiac metabolic dysfunction in fa/fa obese Zucker rats.
    Journal of proteome research, 2013, Apr-05, Volume: 12, Issue:4

    Topics: Adipose Tissue, White; Age Factors; Animals; Betaine; Disease Models, Animal; Inositol; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylation; Myocardium; Obesity; Phosphorylcholine; Rats; Rats, Zucker

2013
Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation.
    Journal of virology, 2013, Volume: 87, Issue:10

    Topics: Animals; Antibodies, Viral; Disease Models, Animal; Encephalitis Virus, Japanese; Encephalitis, Japanese; Female; Japanese Encephalitis Vaccines; Leukocytes, Mononuclear; Methylation; Mice; Mice, Inbred BALB C; RNA, Viral; Survival Analysis; tRNA Methyltransferases; Vaccines, Attenuated

2013
Critical role of transmethylation in TLR signaling and systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2013, Volume: 147, Issue:2

    Topics: Adenine; Animals; Antigen-Presenting Cells; Autoantibodies; B-Lymphocytes; Butyrates; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Female; Immunoglobulin G; Immunosuppressive Agents; Kidney; Lupus Erythematosus, Systemic; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Protein Processing, Post-Translational; Signal Transduction; Toll-Like Receptors

2013
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cytosol; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Inclusion Bodies; Membrane Proteins; Methylation; Methyltransferases; Mutant Proteins; Mutation; Protein Binding; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; Subcellular Fractions

2013
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.
    Cell death & disease, 2013, May-02, Volume: 4

    Topics: Acetylation; Animals; Apoptosis; Bleomycin; Cells, Cultured; Disease Models, Animal; fas Receptor; Fibroblasts; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Pulmonary Fibrosis

2013
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
    Science (New York, N.Y.), 2013, Jun-14, Volume: 340, Issue:6138

    Topics: Animals; Cell Nucleus; Cellular Senescence; Disease Models, Animal; Fibroblasts; Gene Knockout Techniques; Hand Strength; Humans; Lamin Type A; Membrane Proteins; Metalloendopeptidases; Methylation; Mice; Mice, Mutant Strains; Nuclear Proteins; Progeria; Protein Methyltransferases; Protein Precursors; TOR Serine-Threonine Kinases; Weight Gain

2013
Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
    Nature communications, 2013, Volume: 4

    Topics: Animals; Disease Models, Animal; DNA Damage; DNA Repair; Enzyme Stability; Fibroblasts; HEK293 Cells; Heterochromatin; Histones; Humans; Lamin Type A; Longevity; Lysine; Methylation; Methyltransferases; Mice; Nuclear Proteins; Progeria; Protein Binding; Protein Precursors; Protein Processing, Post-Translational; Repressor Proteins

2013
Promoted interaction of nuclear factor-κB with demethylated cystathionine-β-synthetase gene contributes to gastric hypersensitivity in diabetic rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-22, Volume: 33, Issue:21

    Topics: Amino Acids; Analysis of Variance; Animals; Area Under Curve; Case-Control Studies; Chromatin Immunoprecipitation; CpG Islands; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Dose-Response Relationship, Drug; Electromyography; Enzyme Inhibitors; Female; Ganglia, Spinal; Hypersensitivity; Membrane Potentials; Methylation; Neoplasm Proteins; NF-kappa B; Nucleocytoplasmic Transport Proteins; Oxamic Acid; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Stomach Diseases; Sulfites; Up-Regulation

2013
Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia.
    Biochimica et biophysica acta, 2013, Volume: 1832, Issue:10

    Topics: Animals; Arginine; Diet; Disease Models, Animal; Female; Histones; Hyperhomocysteinemia; Methylation; Proteins; Rats; Rats, Wistar

2013
Enhanced trimethylation of histone h3 mediates impaired expression of hepatic glucose 6-phosphatase expression in offspring from rat dams exposed to hypoxia during pregnancy.
    Reproductive sciences (Thousand Oaks, Calif.), 2014, Volume: 21, Issue:1

    Topics: Animals; Blood Glucose; Cell Line, Tumor; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; Gestational Age; Glucose-6-Phosphatase; Histones; Hypoxia; Intracellular Signaling Peptides and Proteins; Liver; Male; Methylation; Oxygen; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational; Rats, Sprague-Dawley; RNA, Messenger; Time Factors

2014
Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Female; Gene Silencing; Humans; Melanoma; Methotrexate; Methylation; Mice; Myosin Heavy Chains; Myosin Type V; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays

2013
Modulation of allogeneic CD8+ T-cell response by DZNep controls GVHD while preserving hematopoietic chimerism.
    Transplantation, 2013, Nov-15, Volume: 96, Issue:9

    Topics: Adenosine; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Fas Ligand Protein; Female; Graft vs Host Disease; Granzymes; Hematopoietic Stem Cell Transplantation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Male; Methylation; Mice; Mice, Inbred C3H; T-Lymphocytes, Cytotoxic; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transplantation Chimera; Transplantation Tolerance; Transplantation, Homologous; Tumor Necrosis Factor-alpha

2013
Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings.
    Molecular genetics and metabolism, 2013, Volume: 110 Suppl

    Topics: Acids, Acyclic; Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Isoleucine; Large Neutral Amino Acid-Transporter 1; Methylation; Mice; Mice, Transgenic; Molecular Targeted Therapy; Organ Specificity; Phenylalanine; Phenylketonurias; Protein Conformation; Protein Folding; Valine

2013
Amino acids as biomarkers in the SOD1(G93A) mouse model of ALS.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:1

    Topics: Age Factors; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Humans; Longevity; Male; Metabolome; Methionine Sulfoximine; Methylation; Mice; Mice, Transgenic; Mutation; Sex Factors; Superoxide Dismutase; Superoxide Dismutase-1

2014
Protective effect of demethylation treatment on cigarette smoke extract-induced mouse emphysema model.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:2

    Topics: Animals; Apoptosis; Azacitidine; Decitabine; Disease Models, Animal; DNA-Binding Proteins; Electron Transport Complex IV; Emphysema; Lung; Male; Methylation; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Proteins; RNA, Messenger; Smoking; Transcription Factors

2013
Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:11

    Topics: Animals; Cell Line; Disease Models, Animal; Histones; Homeodomain Proteins; Humans; Lectins, C-Type; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Mutant Proteins; Mutation; Myelodysplastic Syndromes; Myelopoiesis; Peptide Fragments; Receptors, Cell Surface; Repressor Proteins

2013
Epigenetic mechanisms of Rubinstein-Taybi syndrome.
    Neuromolecular medicine, 2014, Volume: 16, Issue:1

    Topics: Acetylation; Animals; Chromatin; CREB-Binding Protein; Disease Models, Animal; Epigenesis, Genetic; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; MicroRNAs; Models, Biological; Mutation; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Rubinstein-Taybi Syndrome; Sequence Deletion; Tumor Suppressor Protein p53

2014
Pulmonary vasodilation by acetazolamide during hypoxia: impact of methyl-group substitutions and administration route in conscious, spontaneously breathing dogs.
    Journal of applied physiology (Bethesda, Md. : 1985), 2014, Apr-01, Volume: 116, Issue:7

    Topics: Acetazolamide; Administration, Inhalation; Administration, Oral; Animals; Arterial Pressure; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Dogs; Female; Hypoxia; Infusions, Intravenous; Methylation; Pulmonary Artery; Respiration; Structure-Activity Relationship; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents

2014
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:6

    Topics: Animals; Arginine; Brain; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Histones; Homocysteine; Homocystinuria; Liver; Methylation; Mice; S-Adenosylhomocysteine

2014
Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:5

    Topics: Animals; Cell Differentiation; Chromatin; Colitis; Disease Models, Animal; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Methylation; Mice; Mice, Knockout; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta1

2014
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 41, Issue:3

    Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins

2014
Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures.
    The Journal of biological chemistry, 2014, May-30, Volume: 289, Issue:22

    Topics: Action Potentials; Animals; Arginine; Brain; Cell Line; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Kainic Acid; Kidney; Male; Mass Spectrometry; Methylation; NAV1.2 Voltage-Gated Sodium Channel; Phosphorylation; Proteomics; Rats

2014
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.
    Blood, 2014, Jun-19, Volume: 123, Issue:25

    Topics: Animals; B-Lymphocytes; Blotting, Western; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Profiling; Histones; Humans; Kaplan-Meier Estimate; Lymphoma; Lymphoma, B-Cell; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Polycomb Repressive Complex 2; Proto-Oncogene Proteins c-myc; Spleen

2014
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.
    British journal of pharmacology, 2014, Volume: 171, Issue:17

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Betaine; Cells, Cultured; Cytoprotection; Disease Models, Animal; Hep G2 Cells; Humans; Lipolysis; Liver Diseases, Alcoholic; Male; Methylation; Mice; Mice, Inbred C57BL

2014
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
    Nature, 2014, Jun-12, Volume: 510, Issue:7504

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Pancreatic Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins A-raf; Signal Transduction

2014
Histone modifications of the Crhr1 gene in a rat model of depression following chronic stress.
    Behavioural brain research, 2014, Sep-01, Volume: 271

    Topics: Animals; Blotting, Western; Chronic Disease; Depression; Disease Models, Animal; Histones; Hypothalamus; Male; Methylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Stress, Psychological

2014
Effects of acute and sub-chronic L-dopa therapy on striatal L-dopa methylation and dopamine oxidation in an MPTP mouse model of Parkinsons disease.
    Life sciences, 2014, Aug-06, Volume: 110, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Catechol O-Methyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Levodopa; Male; Methylation; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Parkinsonian Disorders; Time Factors

2014
Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury.
    The American journal of pathology, 2014, Volume: 184, Issue:8

    Topics: Acetylation; Acute Lung Injury; Animals; Azacitidine; Blotting, Western; Capillary Permeability; Cell Proliferation; Cell Survival; Chromatin Immunoprecipitation; Decitabine; Disease Models, Animal; Drug Therapy, Combination; Endothelial Cells; Endotoxemia; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Hydroxamic Acids; In Situ Nick-End Labeling; Inflammation; Lung; Male; Methylation; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction

2014
Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:12

    Topics: Alzheimer Disease; Animals; Coffee; Disease Models, Animal; Female; Methylation; Neuroprotective Agents; Protein Phosphatase 2; Rats; Rats, Transgenic; Serotonin

2014
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: structure-activity relationship considerations.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:8

    Topics: Animals; Bone Density Conservation Agents; Carboxylic Acids; Cell Line; Cell Proliferation; Denervation; Disease Models, Animal; Female; Humans; Injections, Intraperitoneal; Interleukin-6; Methylation; Mice, Inbred C57BL; Molecular Structure; Naphthoquinones; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Random Allocation; Sciatic Nerve; Structure-Activity Relationship; Vitamin K

2014
Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain.
    Molecular pain, 2014, Aug-13, Volume: 10

    Topics: Animals; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Methylation; Mice; Morphine; Neuralgia; Neuroblastoma; Pain Measurement; Pain Threshold; Promoter Regions, Genetic; Receptors, Opioid, mu; Sensory Receptor Cells; Spinal Cord

2014
Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis.
    Molecular neurobiology, 2015, Volume: 52, Issue:1

    Topics: Aminoglycosides; Animals; Apoptosis; Benzamidines; Caspase 3; Cyclopropanes; Cytoprotection; Disease Models, Animal; Hair Cells, Auditory; Histone Demethylases; Histones; Lysine; Methylation; Mice, Inbred C57BL; Neomycin; Organ of Corti; Phenyl Ethers; Piperazines

2015
Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12

    Topics: Animals; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Heterografts; Histones; Humans; Kidney Neoplasms; Methylation; Mice; RNA, Long Noncoding; RNA, Small Interfering; Tumor Burden

2014
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
    Science (New York, N.Y.), 2014, Aug-29, Volume: 345, Issue:6200

    Topics: Amino Acid Substitution; Animals; Chromatin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Silencing; Glioma; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methionine; Methylation; Mutation; Signal Transduction

2014
Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet.
    Neurobiology of disease, 2015, Volume: 73

    Topics: Animals; Anxiety; Azacitidine; Brain; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Decitabine; Diet, Fat-Restricted; Disease Models, Animal; Enzyme Inhibitors; Fatty Acids, Omega-3; Female; Male; Maze Learning; Methylation; Mice; Neuroblastoma; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcription Factors

2015
Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.
    BMC cancer, 2014, Oct-09, Volume: 14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Endometrial Neoplasms; Female; Histone Demethylases; Histones; Humans; Methylation; Mice; Neoplasm Grading; Tumor Burden; Xenograft Model Antitumor Assays

2014
Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.
    Nucleic acids research, 2014, Nov-10, Volume: 42, Issue:20

    Topics: Alternative Splicing; Animals; Base Pair Mismatch; Disease Models, Animal; HeLa Cells; Humans; Methylation; Myotonic Dystrophy; Nucleic Acid Conformation; Pseudouridine; Repetitive Sequences, Nucleic Acid; RNA; RNA-Binding Proteins; Water; Zebrafish

2014
Increased plasma S-adenosylhomocysteine-accelerated atherosclerosis is associated with epigenetic regulation of endoplasmic reticulum stress in apoE-/- mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; S-Adenosylhomocysteine; Time Factors; Up-Regulation

2015
Characterization of albendazole-randomly methylated-β-cyclodextrin inclusion complex and in vivo evaluation of its antihelmitic activity in a murine model of Trichinellosis.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Albendazole; Animals; Antiparasitic Agents; beta-Cyclodextrins; Calorimetry, Differential Scanning; Disease Models, Animal; Macromolecular Substances; Mass Spectrometry; Methylation; Mice; Muscle, Skeletal; Solubility; Trichinellosis; X-Ray Diffraction

2014
EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.
    Chemistry & biology, 2014, Nov-20, Volume: 21, Issue:11

    Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Histones; Humans; Kinetics; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methylation; Mice; Mice, Nude; Mutation; Peptides; Polycomb Repressive Complex 2; Small Molecule Libraries; Transplantation, Heterologous

2014
Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Feb-15, Volume: 308, Issue:4

    Topics: Age Factors; Animals; Binding Sites; Brain-Derived Neurotrophic Factor; Choline; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gestational Age; Hippocampus; Histone Deacetylase 1; Histones; Iron; Iron Deficiencies; Iron Metabolism Disorders; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Promoter Regions, Genetic; Rats, Sprague-Dawley; RNA Polymerase II; Time Factors; Upstream Stimulatory Factors

2015
Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.
    Scientific reports, 2015, Feb-06, Volume: 5

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Case-Control Studies; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Lymphatic Metastasis; Male; Methylation; Middle Aged; Neoplasm Grading; Neoplasm Staging; Tumor Burden; Urinary Bladder Neoplasms

2015
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.
    Nature immunology, 2015, Volume: 16, Issue:5

    Topics: Actins; Animals; Cell Adhesion; Cell Movement; Cell Nucleus; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enhancer of Zeste Homolog 2 Protein; Humans; Lymphocyte Activation; Methylation; Mice; Mice, Knockout; Multiple Sclerosis; Neutrophils; Polycomb Repressive Complex 2; Protein Binding; Proto-Oncogene Proteins c-vav; Talin; Transendothelial and Transepithelial Migration

2015
Demethylation of IGFBP5 by Histone Demethylase KDM6B Promotes Mesenchymal Stem Cell-Mediated Periodontal Tissue Regeneration by Enhancing Osteogenic Differentiation and Anti-Inflammation Potentials.
    Stem cells (Dayton, Ohio), 2015, Volume: 33, Issue:8

    Topics: Animals; Cell Differentiation; Disease Models, Animal; Histones; Humans; Insulin-Like Growth Factor Binding Protein 5; Jumonji Domain-Containing Histone Demethylases; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methylation; Osteogenesis; Periodontitis; Periodontium; Regeneration; Swine; Swine, Miniature

2015
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
    Experimental hematology, 2015, Volume: 43, Issue:7

    Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells

2015
Long-term metabolic alterations in a febrile seizure model.
    The International journal of neuroscience, 2016, Volume: 126, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Disease Models, Animal; Histones; Lipid Metabolism; Liver; Male; Methylation; Rats; Rats, Inbred Strains; Seizures, Febrile; Time

2016
Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats.
    Pain, 2015, Volume: 156, Issue:10

    Topics: Action Potentials; Animals; Antineoplastic Agents; Bone Neoplasms; Case-Control Studies; Disease Models, Animal; Enzyme Inhibitors; Female; Ganglia, Spinal; Hyperalgesia; Methylation; Neurons; NF-kappa B; Nitriles; Pain; Pain Management; Pain Threshold; Proline; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Sulfones; Thiocarbamates

2015
Schizophrenia-Like Phenotype Inherited by the F2 Generation of a Gestational Disruption Model of Schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:2

    Topics: Animals; Disease Models, Animal; DNA Methylation; Dopaminergic Neurons; Female; Hippocampus; Male; Methylation; Methylazoxymethanol Acetate; Parvalbumins; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Transcription Factors; Ventral Tegmental Area

2016
H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Aug-15, Volume: 195, Issue:4

    Topics: Animals; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; DNA Methylation; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Fluorouracil; Gene Expression Profiling; Gene Silencing; Genome-Wide Association Study; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Indoles; Inhibitory Concentration 50; Liver; Methylation; Methyltransferases; Mice; Promoter Regions, Genetic; Repressor Proteins; Tumor Escape; Xenograft Model Antitumor Assays

2015
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
    Journal of hepatology, 2016, Volume: 64, Issue:2

    Topics: Animals; Autophagy; Cell Culture Techniques; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Methionine; Methylation; Mice; Protein Phosphatase 2; S-Adenosylmethionine

2016
GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Ovarian Neoplasms; Xenograft Model Antitumor Assays

2015
Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis.
    Nature communications, 2016, Jan-13, Volume: 7

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Gene Knock-In Techniques; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methylation; Mice; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Stability; Retinal Neovascularization; Retinopathy of Prematurity; Reverse Transcriptase Polymerase Chain Reaction

2016
A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation.
    Cell reports, 2016, Feb-09, Volume: 14, Issue:5

    Topics: Aggression; Animals; Brain; CpG Islands; Dendritic Spines; Disease Models, Animal; Gene Expression Regulation; Genes, X-Linked; Histone Demethylases; Histones; Intellectual Disability; Lysine; Memory; Methylation; Mice, Knockout; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Social Behavior; Transcription, Genetic

2016
Methylthioadenosine (MTA) Regulates Liver Cells Proteome and Methylproteome: Implications in Liver Biology and Disease.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:5

    Topics: Animals; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Deoxyadenosines; Disease Models, Animal; Female; Fluorocarbons; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Male; Methylation; Mice; Proteome; Purine-Nucleoside Phosphorylase; Signal Transduction; Thionucleosides

2016
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
    Scientific reports, 2016, Feb-12, Volume: 6

    Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Nucleus; Dipeptides; Disease Models, Animal; Drosophila melanogaster; Eye; Frontotemporal Dementia; Genes, Insect; Genetic Testing; HeLa Cells; Humans; Methylation; Repetitive Sequences, Amino Acid; RNA Interference

2016
Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:7 Pt B

    Topics: Adaptation, Physiological; Animals; Cardiomegaly; Cardiomyopathies; Chromatin; Chromatin Assembly and Disassembly; CpG Islands; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Helicases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Gestational Age; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice, Knockout; Myocardium; Myosin Heavy Chains; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Recovery of Function; Signal Transduction; Stress, Physiological; Transcription Factors; Ventricular Function, Left

2016
Role of annexin gene and its regulation during zebrafish caudal fin regeneration.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2016, Volume: 24, Issue:3

    Topics: Amputation, Surgical; Animal Fins; Animals; Annexins; Blotting, Western; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Histones; Lysine; Methylation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Regeneration; Zebrafish

2016
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model.
    Clinical epigenetics, 2016, Volume: 8

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; MCF-7 Cells; Methylation; Mice; Mice, Nude

2016
Lysine deacetylase inhibition attenuates hypertension and is accompanied by acetylation of mineralocorticoid receptor instead of histone acetylation in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:7

    Topics: Acetylation; Age Factors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hypertension; Immediate-Early Proteins; Methylation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; RNA Polymerase II; Transcription Factors; Valproic Acid

2016
Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Animals; Caspase 3; Disease Models, Animal; DNA Methylation; Ethanol; Female; Free Radicals; Gene Expression Regulation, Developmental; Hippocampus; Histones; Methylation; Mice; Oxidative Stress; Pregnancy; Wnt Proteins

2016
Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals.
    eLife, 2016, 05-05, Volume: 5

    Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; DNA; Hedgehog Proteins; Histone-Lysine N-Methyltransferase; Humans; Kruppel-Like Transcription Factors; Methylation; Mice; Neoplasm Metastasis; Nerve Tissue Proteins; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Signal Transduction; Zinc Finger Protein Gli3

2016
S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis.
    Molecular cell, 2016, 05-05, Volume: 62, Issue:3

    Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adiposity; Animals; CCAAT-Enhancer-Binding Proteins; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; HeLa Cells; Histones; Humans; Male; Methylation; Mice; Obesity; Phosphorylation; PPAR gamma; Protein Processing, Post-Translational; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Transcription, Genetic; Transfection; Wnt Proteins; Wnt Signaling Pathway

2016
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
    Cancer discovery, 2016, Volume: 6, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Disease Models, Animal; DNA-Binding Proteins; F-Box Proteins; Female; Gene Expression Regulation, Leukemic; Heterografts; High-Throughput Nucleotide Sequencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intercellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Transcription Factors

2016
The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration.
    Skeletal muscle, 2016, Volume: 6

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Elapid Venoms; Gene Expression Regulation, Developmental; Genotype; Histone-Lysine N-Methyltransferase; Histones; Kinetics; Methylation; Mice, Inbred C57BL; Mice, Knockout; Muscle Development; Muscle, Skeletal; Muscular Diseases; Phenotype; Regeneration; Satellite Cells, Skeletal Muscle; Signal Transduction

2016
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.
    Genes & development, 2016, 06-01, Volume: 30, Issue:11

    Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Interleukin-3 Receptor alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Knockout; Protein Binding; Tamoxifen

2016
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53.
    Oncogene, 2017, 01-05, Volume: 36, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Mutation; Neoplastic Stem Cells; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2017
Increased apoptosis and abnormal visual behavior by histone modifications with exposure to para-xylene in developing Xenopus.
    Neuroscience, 2016, 09-07, Volume: 331

    Topics: Acetylation; Animals; Apoptosis; Avoidance Learning; Developmental Disabilities; Disease Models, Animal; Freezing Reaction, Cataleptic; Glucuronates; Histone Code; Histones; Methylation; Neuroprotective Agents; Superior Colliculi; Visual Perception; Xenopus laevis; Xylenes

2016
Protein arginine methylation facilitates KCNQ channel-PIP2 interaction leading to seizure suppression.
    eLife, 2016, 07-28, Volume: 5

    Topics: Animals; Arginine; Disease Models, Animal; Epilepsy; KCNQ Potassium Channels; Methylation; Mice, Inbred C57BL; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

2016
Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress.
    Neurobiology of disease, 2016, Volume: 96

    Topics: 5-Methylcytosine; Animals; Chromatin Immunoprecipitation; Disease Models, Animal; Epigenesis, Genetic; Female; Gene Ontology; Hippocampus; Male; Methylation; Mice; Mice, Inbred C57BL; Sex Factors; Stress, Psychological

2016
Hypermethylation of the CaSR and VDR genes in the parathyroid glands in chronic kidney disease rats with high-phosphate diet.
    Human cell, 2016, Volume: 29, Issue:4

    Topics: Animals; Chronic Disease; Disease Models, Animal; DNA Methylation; Gene Expression; Hyperparathyroidism, Secondary; Kidney Diseases; Male; Methylation; Parathyroid Glands; Phosphorus, Dietary; Proteins; Rats; Rats, Wistar; Receptors, Calcitriol; Receptors, Calcium-Sensing; RNA, Messenger

2016
DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis.
    Neoplasia (New York, N.Y.), 2016, Volume: 18, Issue:9

    Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epithelial-Mesenchymal Transition; Gene Silencing; Histones; Homeodomain Proteins; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Methylation; Mice; Neoplasm Metastasis; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Kinase C-alpha; Repressor Proteins; RNA Interference; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger E-box Binding Homeobox 2

2016
Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells.
    Placenta, 2016, Volume: 46

    Topics: Animals; Cytokines; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Fatty Acid-Binding Proteins; Female; Lipid Metabolism; Methylation; MicroRNAs; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Promoter Regions, Genetic; Rats, Sprague-Dawley; Up-Regulation

2016
Adenosine 5'-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Acetaminophen; Adenosine Monophosphate; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase Kinase 5; Methylation; Mice, Inbred C57BL; Protective Agents; Proteolysis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Time Factors; Ubiquitination

2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 02-15, Volume: 198, Issue:4

    Topics: Animals; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Humans; Immunologic Memory; Inflammation; Interleukin-2; Lymphocyte Activation; Methylation; Mice; NF-kappa B; Protein-Arginine N-Methyltransferases; T-Lymphocytes, Helper-Inducer; Th1 Cells; Th2 Cells; Up-Regulation

2017
Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline.
    Neurotoxicity research, 2017, Volume: 31, Issue:4

    Topics: Animals; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Food Preferences; Hippocampus; Histone-Lysine N-Methyltransferase; Histones; Immobility Response, Tonic; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Microfilament Proteins; Microglia; Minocycline; Rats; Receptors, AMPA; Receptors, Immunologic; Receptors, N-Methyl-D-Aspartate; Social Isolation

2017
Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition.
    Infection and immunity, 2017, Volume: 85, Issue:4

    Topics: Animals; Antibodies, Bacterial; Bacterial Proteins; Base Sequence; Disease Models, Animal; Female; Gene Expression Regulation, Bacterial; Humans; Immune Sera; Immunization; Methylation; Mice; O Antigens; Operon; Salmonella typhi; Typhoid Fever

2017
Involvement of histone methylation in macrophage apoptosis and unstable plaque formation in methionine-induced hyperhomocysteinemic ApoE
    Life sciences, 2017, Mar-15, Volume: 173

    Topics: Animals; Apolipoproteins E; Apoptosis; Disease Models, Animal; Histones; Hyperhomocysteinemia; Methionine; Methylation; Mice; Mice, Knockout; Plaque, Atherosclerotic

2017
Wolf-Hirschhorn syndrome candidate 1-like 1 epigenetically regulates nephrin gene expression.
    American journal of physiology. Renal physiology, 2017, 06-01, Volume: 312, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Cytoskeletal Proteins; Disease Models, Animal; Doxorubicin; Epigenesis, Genetic; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Nephrotic Syndrome; Nuclear Proteins; Podocytes; Promoter Regions, Genetic; RNA Interference; Transfection; Zebrafish; Zebrafish Proteins

2017
MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response.
    Scientific reports, 2017, 03-15, Volume: 7, Issue:1

    Topics: Animals; Cells, Cultured; Chromatin Immunoprecipitation; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Lipopolysaccharides; Macrophages, Peritoneal; Methylation; Mice; Shock, Septic; THP-1 Cells; Trans-Activators; Transcription Factor RelA

2017
Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
    Genes and immunity, 2008, Volume: 9, Issue:4

    Topics: Animals; CD11a Antigen; CD27 Ligand; Cell Separation; Cells, Cultured; Disease Models, Animal; Doxycycline; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Interferons; Lupus Erythematosus, Systemic; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Oligonucleotide Array Sequence Analysis; Repressor Proteins; RNA, Messenger; T-Lymphocytes

2008
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents

2008
Species-specific transcription in mice carrying human chromosome 21.
    Science (New York, N.Y.), 2008, Oct-17, Volume: 322, Issue:5900

    Topics: Animals; Base Sequence; Cell Nucleus; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Gene Expression Regulation; Hepatocyte Nuclear Factors; Hepatocytes; Histones; Humans; Methylation; Mice; Oligonucleotide Array Sequence Analysis; Regulatory Sequences, Nucleic Acid; Species Specificity; Transcription Initiation Site; Transcription, Genetic

2008
Reconstructing the disease model and epigenetic networks for MLL-AF4 leukemia.
    Cancer cell, 2008, Nov-04, Volume: 14, Issue:5

    Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2008
Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:4

    Topics: Acetylation; Acute Disease; Alcoholism; Animals; Central Nervous System Depressants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Epigenesis, Genetic; Ethanol; Gene Expression Regulation; Hepatocytes; Histones; Intercellular Signaling Peptides and Proteins; Liver; Male; Methylation; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Rats, Wistar

2009
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.
    Cardiovascular research, 2009, Apr-01, Volume: 82, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Endotoxemia; Isoquinolines; Lipopolysaccharides; Methylation; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Methyltransferases; Protein Phosphatase 2; Protein Phosphatase 2C; Protein Processing, Post-Translational; Receptor, Adenosine A1; Sulfonamides; Time Factors; Troponin I

2009
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.
    Acta physiologica (Oxford, England), 2009, Volume: 197, Issue:1

    Topics: Analysis of Variance; Animal Feed; Animals; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Female; Homocystine; Hyperhomocysteinemia; Kidney; Liver; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Statistics, Nonparametric; Tissue Distribution

2009
In vitro and murine efficacy and toxicity studies of nebulized SCC1, a methylated caffeine-silver(I) complex, for treatment of pulmonary infections.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Caffeine; Cell Line; Disease Models, Animal; Male; Methane; Methylation; Mice; Mice, Inbred C57BL; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Silver Compounds

2009
Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jun-17, Volume: 29, Issue:24

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chromatin; Chromatin Immunoprecipitation; CREB-Binding Protein; Depression; Disease Models, Animal; Dominance-Subordination; Gene Expression; Genome-Wide Association Study; Histones; Imipramine; Male; Methylation; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Social Isolation

2009
Epigenetic regulation of the alternatively activated macrophage phenotype.
    Blood, 2009, Oct-08, Volume: 114, Issue:15

    Topics: Animals; Chromatin Assembly and Disassembly; Disease Models, Animal; Epigenesis, Genetic; Female; Genetic Markers; Histones; Humans; Interleukin-4; Jumonji Domain-Containing Histone Demethylases; Macrophage Activation; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Schistosoma mansoni; Schistosomiasis mansoni; Signal Transduction; STAT6 Transcription Factor; Transcriptional Activation

2009
Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Dec-03, Volume: 140, Issue:2

    Topics: Acetylation; Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Viral; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Compounding; Female; Immunization Schedule; Immunoglobulin A, Secretory; Immunoglobulin G; Influenza A virus; Influenza Vaccines; Methylation; Mice; Mice, Inbred C57BL; Molecular Structure; Nasal Lavage Fluid; Orthomyxoviridae Infections; Structure-Activity Relationship; Time Factors; Vaccines, Inactivated

2009
Decreased arginine methylation and myelin alterations in arsenic exposed rats.
    Neurotoxicology, 2010, Volume: 31, Issue:1

    Topics: Analysis of Variance; Animals; Arginine; Arsenic; Arsenic Poisoning; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Methylation; Myelin Sheath; Organ Size; Rats; Rats, Wistar; Time Factors

2010
Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model.
    Experimental neurology, 2010, Volume: 222, Issue:2

    Topics: Action Potentials; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Ganglia, Spinal; In Situ Nick-End Labeling; Methylation; Motor Activity; Muscle, Skeletal; Nerve Regeneration; Neurites; Neurons; Oncogene Protein v-akt; Rats; Rats, Wistar; Recovery of Function; Sciatic Neuropathy; Sensation; Tubulin; Vitamin B 12

2010
The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.
    Experimental and molecular pathology, 2010, Volume: 88, Issue:3

    Topics: Animal Nutritional Physiological Phenomena; Animals; Disease Models, Animal; Ethanol; Gene Expression; Histones; Liver; Liver Diseases, Alcoholic; Male; Methylation; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; S-Adenosylmethionine

2010
L-methionine decreases dendritic spine density in mouse frontal cortex.
    Neuroreport, 2010, Jun-02, Volume: 21, Issue:8

    Topics: Animals; Anticonvulsants; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Cell Shape; Dendritic Spines; Disease Models, Animal; Down-Regulation; Drug Interactions; Extracellular Matrix Proteins; Frontal Lobe; GABA Agents; Male; Methionine; Methylation; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Reelin Protein; Schizophrenia; Serine Endopeptidases; Synapses; Valproic Acid

2010
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:3

    Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency

2011
alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract.
    Current eye research, 2010, Volume: 35, Issue:7

    Topics: Acetylation; alpha-Crystallins; Animals; Antioxidants; Cataract; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Lens, Crystalline; Methylation; Molecular Chaperones; Naphthalenes; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Thioctic Acid

2010
Cardiac myosin heavy chain gene regulation by thyroid hormone involves altered histone modifications.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:6

    Topics: Acetylation; Animals; Binding Sites; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Disease Models, Animal; DNA, Intergenic; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Hyperthyroidism; Hypothyroidism; Methylation; Myocardium; Myosin Heavy Chains; Polymerase Chain Reaction; Promoter Regions, Genetic; Propylthiouracil; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; RNA Precursors; RNA, Messenger; Time Factors; Transcription, Genetic; Triiodothyronine; Ventricular Myosins

2010
Gastroprotective effect and cytotoxicity of carnosic acid derivatives.
    Planta medica, 2011, Volume: 77, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Animals; Anti-Ulcer Agents; Antioxidants; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lansoprazole; Male; Methylation; Mice; Plant Components, Aerial; Plant Extracts; Random Allocation; Rosmarinus; Stomach Ulcer; Structure-Activity Relationship

2011
Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.
    European journal of pharmacology, 2011, May-20, Volume: 659, Issue:1

    Topics: Animals; Behavior, Animal; Benzimidazoles; Cyclopropanes; Cytochrome P-450 Enzyme System; Disease Models, Animal; Essential Tremor; Gene Deletion; Harmaline; Hydroxylation; Methylation; Mibefradil; Mice; Naphthalenes; Receptors, GABA-A; Structure-Activity Relationship; Testosterone

2011
The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis.
    Biochimica et biophysica acta, 2011, Volume: 1811, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Cholestasis, Intrahepatic; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Female; Immunoblotting; Intestine, Small; Liver Failure; Liver Function Tests; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Sodium

2011
Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, May-11, Volume: 31, Issue:19

    Topics: alpha-Synuclein; Animals; Astrocytes; Blotting, Western; Brain; Cell Line; Cells, Cultured; Dendrites; Disease Models, Animal; Immunohistochemistry; Methylation; Mice; Mice, Transgenic; Microglia; Neurodegenerative Diseases; Neurons; Phosphoprotein Phosphatases; Phosphorylation; Serotonin

2011
Can the rat be used as a valid model of human esophageal adenocarcinoma?
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2012, Volume: 25, Issue:2

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; CpG Islands; Disease Models, Animal; Esophageal Neoplasms; Esophagus; Gastroesophageal Reflux; Humans; Methylation; Rats

2012
Intrauterine growth restriction leads to changes in sulfur amino acid metabolism, but not global DNA methylation, in Yucatan miniature piglets.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:9

    Topics: Amino Acids, Sulfur; Animals; Animals, Inbred Strains; Animals, Newborn; Betaine-Homocysteine S-Methyltransferase; Cystathionine gamma-Lyase; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; Humans; Liver; Male; Methylation; Organ Size; RNA, Messenger; Swine; Swine, Miniature; Taurine

2012
Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer-membrane protein OmpL32.
    Microbiology (Reading, England), 2012, Volume: 158, Issue:Pt 3

    Topics: Animals; Bacterial Proteins; Cricetinae; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Kidney; Leptospira interrogans; Leptospirosis; Liver; Methylation; Microscopy, Fluorescence; Porins; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
    Molecular genetics and metabolism, 2012, Volume: 105, Issue:3

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha

2012
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
    Nature, 2012, Mar-07, Volume: 484, Issue:7392

    Topics: Animals; Carrier Proteins; Cell Cycle; Cell Line; Chromatin; Congenital Microtia; Crystallography, X-Ray; Disease Models, Animal; DNA Replication; Dwarfism; Ear; Growth Disorders; Histones; Humans; Lysine; Methylation; Micrognathism; Models, Molecular; Origin Recognition Complex; Patella; Protein Structure, Tertiary; Replication Origin; Zebrafish; Zebrafish Proteins

2012
Epigenetic bystander-like effects of stroke in somatic organs.
    Aging, 2012, Volume: 4, Issue:3

    Topics: Acetylation; Animals; Bystander Effect; Disease Models, Animal; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Histones; Kidney; Liver; Male; Methyl-CpG-Binding Protein 2; Methylation; MicroRNAs; Myocardium; Rats; Rats, Long-Evans; Stroke

2012
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
    Journal of the neurological sciences, 2012, Jul-15, Volume: 318, Issue:1-2

    Topics: Acute Disease; Animals; Arginase; Arginine; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Male; Methylation; Multiple Sclerosis; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley

2012
Novel mutations target distinct subgroups of medulloblastoma.
    Nature, 2012, Aug-02, Volume: 488, Issue:7409

    Topics: Animals; Antigens, CD; beta Catenin; Cadherins; Cdh1 Proteins; Cell Cycle Proteins; Cell Lineage; Cerebellar Neoplasms; Child; Class I Phosphatidylinositol 3-Kinases; CREB-Binding Protein; DEAD-box RNA Helicases; Disease Models, Animal; DNA Copy Number Variations; DNA Helicases; DNA Mutational Analysis; Genome, Human; Genomics; Hedgehog Proteins; Histone Demethylases; Histones; Humans; Medulloblastoma; Methylation; Mice; Mutation; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Transcription Factors; Wnt Proteins

2012
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
    The Journal of nutrition, 2013, Volume: 143, Issue:1

    Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation

2013
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
Transcription elongation and tissue-specific somatic CAG instability.
    PLoS genetics, 2012, Volume: 8, Issue:11

    Topics: Animals; Chromatin; Corpus Striatum; Disease Models, Animal; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Organ Specificity; Transcription, Genetic; Trinucleotide Repeat Expansion

2012
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-01, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Indoles; Methylation; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Sulfonamides; Vemurafenib

2013
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:3

    Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex

2013
Cerebral postischemic reperfusion-induced demethylation of the protein phosphatase 2A catalytic subunit.
    Journal of neuroscience research, 2002, Aug-15, Volume: 69, Issue:4

    Topics: Animals; Brain Ischemia; Catalytic Domain; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Hippocampus; Immunohistochemistry; Methylation; Mitogen-Activated Protein Kinases; Neurons; Phosphoprotein Phosphatases; Protein Isoforms; Protein Phosphatase 2; Rats; Rats, Wistar; Reperfusion Injury; Ribosomal Protein S6 Kinases; Telencephalon

2002
L-methionine supplementation accelerates tumour growth and shifts the phospholipid derivative pattern in a murine model of malignant melanoma. A proton HRMAS NMR spectroscopy study.
    IARC scientific publications, 2002, Volume: 156

    Topics: Animals; Cell Division; Dietary Supplements; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Melanoma; Methionine; Methylation; Mice; Mice, Inbred C57BL; Phospholipids

2002
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
    Gastroenterology, 2003, Volume: 124, Issue:5

    Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis

2003
Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo.
    Journal of natural products, 2003, Volume: 66, Issue:6

    Topics: Acylation; Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Disease Models, Animal; Drug Screening Assays, Antitumor; Flavonoids; Humans; Indonesia; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Male; Methylation; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured; Vitex

2003
Antagonism of hypervitaminosis A-induced anterior neural tube closure defects with a methyl-donor deficiency in murine whole-embryo culture.
    The Journal of nutrition, 2003, Volume: 133, Issue:11

    Topics: Animals; Diet; Disease Models, Animal; Embryonic and Fetal Development; Female; Hypervitaminosis A; Male; Methylation; Mice; Mice, Inbred ICR; Neural Tube Defects; Organ Culture Techniques; Pregnancy; Rats

2003
Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes.
    Virus research, 2003, Volume: 98, Issue:1

    Topics: Adenoviruses, Human; Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Gene Expression Profiling; Humans; Injections, Intramuscular; Mesocricetus; Methylation; Mice; Neoplasms, Experimental; Neuroectodermal Tumors; Oligonucleotide Array Sequence Analysis; Peritoneal Cavity; Proteins; Sequence Analysis, DNA; Transcription, Genetic; Viral Proteins; Virus Integration

2003
Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: Amino Acid Motifs; Animals; Base Sequence; Binding Sites; Catalytic Domain; Cell Nucleus; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Chromatin; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphatase; Homeodomain Proteins; Islets of Langerhans; Luciferases; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Paired Box Transcription Factors; PAX6 Transcription Factor; Plasmids; Polymerase Chain Reaction; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Rats; Repressor Proteins; Salts; Subcellular Fractions; Trans-Activators; Transcription, Genetic

2004
Temporal evaluation of methionine synthase and related metabolites in the MAC15A mouse adenocarcinoma animal model.
    International journal of cancer, 2004, Nov-20, Volume: 112, Issue:4

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma; Cell Division; Disease Models, Animal; Disease Progression; Humans; Methionine; Methylation; Mice

2004
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
    The Journal of biological chemistry, 2005, Jan-07, Volume: 280, Issue:1

    Topics: Acetylation; Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Phenylbutyrates; Trinucleotide Repeat Expansion; Ubiquitin

2005
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
    Biological psychiatry, 2005, Mar-01, Volume: 57, Issue:5

    Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid

2005
The effects of carboxymethylated chitosan on metalloproteinase-1, -3 and tissue inhibitor of metalloproteinase-1 gene expression in cartilage of experimental osteoarthritis.
    Rheumatology international, 2005, Volume: 26, Issue:1

    Topics: Acids; Animals; Antirheumatic Agents; Cartilage, Articular; Chitosan; Disease Models, Animal; Gene Expression; Injections, Intra-Articular; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Methylation; Molecular Weight; Osteoarthritis; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2005
Oncogene-induced senescence as an initial barrier in lymphoma development.
    Nature, 2005, Aug-04, Volume: 436, Issue:7051

    Topics: ADP-Ribosylation Factors; Animals; Apoptosis; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; Chromosomal Instability; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, ras; Heterochromatin; Lymphoma; Methylation; Methyltransferases; Mice; Mice, Transgenic; Precancerous Conditions; Repressor Proteins; Transgenes; Tumor Suppressor Protein p53

2005
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.
    Nature neuroscience, 2006, Volume: 9, Issue:4

    Topics: Acetylation; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chromatin; Depression; Disease Models, Animal; Hippocampus; Histones; Imipramine; Male; Methylation; Mice; Mice, Inbred C57BL; Stress, Psychological

2006
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:6

    Topics: Aged; Aged, 80 and over; Animals; Arginine; Astrocytes; Blotting, Western; Citrulline; Disease Models, Animal; Down-Regulation; Female; Glaucoma, Open-Angle; Humans; Hydrolases; Immunohistochemistry; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Optic Nerve Diseases; Proteomics; Rats; Rats, Sprague-Dawley; RNA, Messenger

2006
Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: Animals; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models, Animal; DNA Damage; Glioblastoma; Guanine; Humans; Methylation; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2006
Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Methylation; Mice; Mice, Nude; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Structure-Activity Relationship; Thyroid Neoplasms; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2006
Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Nov-28, Volume: 103, Issue:48

    Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Gene Expression Regulation; Male; Methyl-CpG-Binding Protein 2; Methylation; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Protein Binding; Rett Syndrome; Stress, Physiological; Transcription, Genetic; Tyrosine

2006
Proteomic analysis of hepatic iron overload in mice suggests dysregulation of urea cycle, impairment of fatty acid oxidation, and changes in the methylation cycle.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:6

    Topics: Animals; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Enzymes; Fatty Acids; Iron Compounds; Iron Overload; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Proteomics; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urea

2007
Modulation of nucleosome dynamics in Huntington's disease.
    Human molecular genetics, 2007, May-15, Volume: 16, Issue:10

    Topics: Acetylation; Animals; Brain; Chromomycins; Disease Models, Animal; Female; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Plicamycin; Transcription, Genetic

2007
Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CCl4 in the rat.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2

    Topics: Acute Disease; Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Liver Diseases; Male; Methylation; Molecular Structure; Rats; Rats, Wistar; Resveratrol; Stilbenes; Structure-Activity Relationship

2008
Mice deficient in cystathionine beta synthase display altered homocysteine remethylation pathway.
    Molecular genetics and metabolism, 2007, Volume: 91, Issue:4

    Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; Homocysteine; Homocystinuria; Methylation; Mice; MicroRNAs

2007
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:3

    Topics: Acylation; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; BALB 3T3 Cells; Biotransformation; Body Weight; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Kidney Diseases; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Transgenic; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Tissue Distribution

2007
Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice.
    Experimental and molecular pathology, 2008, Volume: 84, Issue:2

    Topics: Acetylation; Animals; Carcinogens; Cell Fractionation; Cell Nucleus; Disease Models, Animal; Drug Antagonism; Drug Combinations; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hepatocytes; Histones; Liver; Male; Methylation; Mice; Mice, Inbred C3H; Oligonucleotide Array Sequence Analysis; Proteins; RNA, Messenger; S-Adenosylmethionine

2008
Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats.
    Neuroscience, 2008, Apr-09, Volume: 152, Issue:4

    Topics: Animals; Cerebral Cortex; Cerebral Infarction; Chromatin Immunoprecipitation; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Methylation; Ovariectomy; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sex Characteristics

2008
Striatal histone modifications in models of levodopa-induced dyskinesia.
    Journal of neurochemistry, 2008, Volume: 106, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylation; Animals; Chromatin; Chromosome Aberrations; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Female; Histones; Levodopa; Macaca mulatta; Male; Methylation; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Phosphorylation; Protein Processing, Post-Translational; Species Specificity

2008
Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.
    Irish journal of medical science, 1980, Volume: 149, Issue:1

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cercopithecus; Disease Models, Animal; Folic Acid; Haplorhini; Macaca fascicularis; Methylation; Methyltransferases; Nerve Tissue; Nitrous Oxide; Peripheral Nervous System Diseases; Spinal Cord Diseases; Vitamin B 12 Deficiency

1980
Increased phospholipid methylation in the myocardium of hyperthyroid rats.
    Biochimica et biophysica acta, 1980, Oct-01, Volume: 632, Issue:2

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Hyperthyroidism; Male; Methylation; Microsomes; Myocardium; Phospholipids; Rats; S-Adenosylmethionine; Thyroxine

1980
Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
    Nature genetics, 1995, Volume: 10, Issue:3

    Topics: Adenosine Deaminase; Animals; Animals, Newborn; Base Sequence; Cell Death; Disease Models, Animal; DNA Primers; Embryonic and Fetal Development; Female; Gene Targeting; Homozygote; Humans; Intestine, Small; Liver; Male; Methylation; Mice; Molecular Sequence Data; Mutation; Pregnancy; Pulmonary Atelectasis; Purines; Severe Combined Immunodeficiency; T-Lymphocyte Subsets

1995
[Histologic and cell kinetic alteration of gastric mucosa under continuous duodenal regurgitation in experimental dog model].
    Nihon Geka Gakkai zasshi, 1994, Volume: 95, Issue:4

    Topics: Animals; Atrophy; Bromodeoxyuridine; Cell Cycle; Disease Models, Animal; DNA; Dogs; Gastric Mucosa; Gastroesophageal Reflux; Hyperplasia; Male; Methylation

1994
Lung tumors in strain A mice: application for studies in cancer chemoprevention.
    Journal of cellular biochemistry. Supplement, 1993, Volume: 17F

    Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Disease Models, Animal; DNA; DNA Damage; Drug Screening Assays, Antitumor; Female; Isothiocyanates; Lung Neoplasms; Male; Methylation; Mice

1993
Synthesis and muscarinic activities of 3-(pyrazolyl)-1,2,5,6-tetrahydropyridine derivatives.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Analysis of Variance; Animals; Binding, Competitive; Disease Models, Animal; Dopamine Agents; Isotope Labeling; Male; Memory; Methylation; Mice; Miosis; Muscarinic Agonists; Muscarinic Antagonists; Mydriasis; Oxotremorine; Pirenzepine; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Salivation; Structure-Activity Relationship; Vas Deferens

1996
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
    Circulation research, 2001, Jun-08, Volume: 88, Issue:11

    Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System

2001
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes

2002
Alcohol interference with the folate enterohepatic cycle.
    Transactions of the Association of American Physicians, 1977, Volume: 90

    Topics: Alcoholism; Animals; Bile; Disease Models, Animal; Enterohepatic Circulation; Female; Folic Acid; Folic Acid Deficiency; Humans; Liver; Methylation; Oxidation-Reduction; Rats

1977
Effects of alcohol consumption on DNA methylation reactions and gene expression: implications for increased cancer risk.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1992, Volume: 1 Suppl 3

    Topics: Animals; Cocarcinogenesis; Disease Models, Animal; DNA Damage; ErbB Receptors; Ethanol; Evaluation Studies as Topic; Gene Expression; Humans; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogenes; Rats; Rats, Sprague-Dawley; Risk Factors

1992
Methylated lysine in storage body protein of sheep with hereditary ceroid-lipofuscinosis.
    Biochimica et biophysica acta, 1992, Feb-14, Volume: 1138, Issue:2

    Topics: Amino Acids; Animals; Brain; Chromatography, Ion Exchange; Chromatography, Thin Layer; Disease Models, Animal; Liver; Lysine; Methylation; Microscopy, Electron; Neuronal Ceroid-Lipofuscinoses; Pancreatin; Proteins; Sheep; Spectrometry, Mass, Fast Atom Bombardment

1992
Antigen induced arthritis in beige (Chediak-Higashi) mice.
    Annals of the rheumatic diseases, 1990, Volume: 49, Issue:8

    Topics: Animals; Antigens; Arthritis; Autoradiography; Cartilage, Articular; Disease Models, Animal; Joints; Male; Methylation; Mice; Mice, Mutant Strains; Peptide Hydrolases; Serum Albumin, Bovine

1990
Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.
    Journal of the neurological sciences, 1986, Volume: 72, Issue:1

    Topics: Animals; Arginine; Brain Diseases; Chiroptera; Cycloleucine; Disease Models, Animal; Liver; Methylation; Myelin Basic Protein; Rats; Rats, Inbred Strains; Vitamin B 12; Vitamin B 12 Deficiency

1986
Human leukemic cells: cytochemical studies on nuclear proteins.
    Chromosoma, 1972, Volume: 38, Issue:3

    Topics: Animals; Cell Line; Cell Nucleus; Cells, Cultured; Cricetinae; Disease Models, Animal; DNA; Female; Genes; Histocytochemistry; Histones; Humans; Infectious Mononucleosis; Leukemia, Lymphoid; Lymphocytes; Male; Methylation; Staining and Labeling

1972
The effect of staphylococcal enterotoxin on the epithelial mucosubstances of the small intestine of rhesus monkeys.
    The American journal of pathology, 1970, Volume: 60, Issue:1

    Topics: Animals; Disease Models, Animal; Enteritis; Enterotoxins; Epithelium; Haplorhini; Histocytochemistry; Intestinal Mucosa; Methylation; Microscopy, Electron; Mucins; Staining and Labeling

1970
Experimental fibrosing alveolitis.
    The American review of respiratory disease, 1972, Volume: 105, Issue:5

    Topics: Animals; Cricetinae; Disease Models, Animal; Injections, Subcutaneous; Methylation; Microscopy, Electron; Nitroso Compounds; Pulmonary Fibrosis; Time Factors; Urethane

1972
Bile salts of spontaneously atherosclerosis-susceptible white Carneau pigeon.
    Steroids, 1971, Volume: 17, Issue:4

    Topics: Animals; Arteriosclerosis; Bile; Bile Acids and Salts; Bird Diseases; Chromatography, Gas; Chromatography, Thin Layer; Columbidae; Disease Models, Animal; Feces; Male; Methylation; Species Specificity; Taurine

1971