isomethyleugenol has been researched along with Disease Models, Animal in 302 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (3.64) | 18.7374 |
1990's | 13 (4.30) | 18.2507 |
2000's | 44 (14.57) | 29.6817 |
2010's | 171 (56.62) | 24.3611 |
2020's | 63 (20.86) | 2.80 |
Authors | Studies |
---|---|
Deng, W; Jiang, M; Li, L; Wang, S | 1 |
Hamada, Y; Inada, E; Iseki, M; Katsuda, Y; Kondo, T; Kuzumaki, N; Matsufuji, M; Mori, T; Narita, M; Sato, D; Takeshima, H; Tanaka, K; Ushijima, T; Yamabe, Y; Yamaguchi, K | 1 |
Matrisciano, F; Pinna, G | 1 |
Fan, L; Shen, F; Sun, D; Wang, Z; Yang, H | 1 |
Chen, X; Dong, J; Gong, W; Guo, B; Jiang, Q; Qin, J; Shao, X; Shen, S; Shi, T; Shi, Y; Zhang, L | 1 |
Jiang, M; Shen, L; Yu, Y; Zhao, J | 1 |
Du, T; Han, R; Li, C; Li, L; Liu, R; Liu, S; Meng, K; Shen, Y; Xiu, J; Xu, L; Xu, Q; Zhu, C; Zhu, W | 1 |
Bach, DH; He, J; Huang, YH; Li, Z; Lin, P; Liu, H; Wang, Z; Yang, J | 1 |
Hou, S; Li, Y; Yang, B; Zhao, J | 1 |
Chen, Y; Gan, W; Li, D; Liu, N; Lu, Y; Ma, W; Yang, L; Yang, Z | 1 |
Chen, Y; Han, P; Lei, Y; Liu, J; Liu, M; Tian, D; Wang, H; Wang, M; Wang, S; Yan, W | 1 |
Dong, Z; Kwon, SH; Lee, BR; Lee, CM; Lee, HK; Lee, TJ; Li, C; O'Connor, PM | 1 |
Dulka, K; Fülöp, F; Gulya, K; Lajkó, N; Mihály, A; Szabo, M; Szatmári, I; Vécsei, L | 1 |
Chen, XY; Cheng, C; Cheng, WC; Dong, KY; Huang, W; Wang, YH; Yu, ZY; Zhang, L; Zuo, XZ | 1 |
Aihara, M; Araie, M; Iejima, D; Iwata, T; Kashiwagi, K; Kimura, C; Kimura, I; Mabuchi, F; Minegishi, Y; Minematsu, N; Nakayama, M; Nakazawa, T; Pan, Y; Shiga, Y; Suga, A; Takamoto, M; Yamamoto, M; Yoshitake, K | 1 |
Chen, S; Lu, YC; Pei, DS; Sun, XL; Wang, Y; Zhang, L; Zhang, LS | 1 |
Andreeva, K; Cave, MC; Head, KZ; Klinge, CM; Petri, BJ; Piell, KM; Rouchka, EC; Wahlang, B | 1 |
Adams, DA; Martin, LJ; Niedzwiecki, MV; Wong, M | 1 |
Chen, W; Han, C; Kwon, H; Ma, W; Song, K; Wu, T; Zhang, J | 1 |
Chen, HN; Dai, L; Dong, L; Fu, S; Huang, C; Luo, L; Nice, EC; Peng, Y; Shen, G; Wang, K; Wang, M; Wang, Z; Wei, X; Wu, X | 1 |
Cueto, R; Hu, W; Ji, Y; Jiang, X; Khan, M; Liu, L; Saredy, J; Sigler, D; Snyder, NW; Wang, H; Wang, X; Wu, S; Xi, H; Yang, X | 1 |
Li, SM; Ma, LL; Wang, BH; Xie, W; Xu, YQ | 1 |
Crews, FT; Dubester, K; Healey, KL; Liu, W; Miller, KM; Swartzwelder, HS | 1 |
Dai, X; He, X; Li, J; Xia, Z; Xiao, H; Yang, R | 1 |
Dai, Z; Li, Y; Qi, S; Wang, G; Wang, L; Wang, Z; Xiang, M | 1 |
Anselmo, A; Bernstein, BE; Brumbaugh, J; Charlton, J; Choi, J; Coffey, A; Di Stefano, B; Hochedlinger, K; Hock, H; Huebner, AJ; Ji, F; Kim, IS; Meissner, A; Sadreyev, RI; Schindler, JW; Schwarz, BA; Walsh, RM | 1 |
Chen, S; Feng, S; Feng, X; Guo, W; Han, M; He, Y; Huang, Y; Jiang, E; Liu, M; Liu, Y; Luo, Y; Ma, Q; Niu, Q; Pang, A; Pei, X; Su, X; Wang, Q; Wei, J; Yang, D; Zhai, W; Zhang, R | 1 |
Du, J; Gao, M; Hao, A; Ji, G; Ji, S; Li, X; Tian, W; Zhou, W | 1 |
Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D | 1 |
Artyomov, MN; Bourgeois-Daigneault, MC; Chen, J; Chubukov, V; Daigneault, A; Esaulova, E; Foulkes, W; Hayes, S; Johnson, RM; Jones, RG; Koning, R; Krawczyk, CM; Larochelle, C; Ma, EH; Mamane, V; Muhire, BM; Pospisilik, JA; Roddy, TP; Roy, DG; Samborska, B; Sheldon, RD; Shorstova, T; Steadman, M; Swain, A; Williams, KS; Witcher, M | 1 |
Khair, L; Messina, LM; Tie, G; Tutto, A; Yan, J | 1 |
Chang, CY; Chen, L; Fung, KS; Huang, LW; Hung, JH; Kao, CF; Li, J | 1 |
Chang, S; Jing, J; Li, B; Liu, X; Shangguan, S; Wang, L; Wu, J; Yao, X; Zhang, T | 1 |
Cazzola, H; Erhardt, M; Grassl, GA; Heidemann, J; Horstmann, JA; Hughes, KT; Kolbe, M; Kühne, C; Lemaire, L; Lokareddy, RK; Lunelli, M; Rossez, Y; Rossi, C; Schlüter, H; Steffen, P; Stradal, TEB; Szefs, S; Uetrecht, C; Wang, C | 1 |
Cui, S; Li, X; Ou, M; Tu, J; Zhao, S | 1 |
Chen, Q; Ji, C; Lin, K; Miao, L; Xu, A; Yang, J; Yang, L; Yu, Y; Zhang, X | 1 |
Aziz, N; Cho, JY; Han, JW; Han, SY; Kim, E; Kim, HG; Kim, JH; Kim, S; Lee, Y; Parameswaran, N; Yang, WS; Yi, YS; Yoo, BC | 1 |
Bae, WK; Hennighausen, L; Lau-Corona, D; Waxman, DJ | 1 |
Bonefas, KM; Collette, KM; Dou, Y; Garay, PM; Iwase, S; Keegan, CE; Porter, RS; Raines, B; Seo, YA; Tronson, NC; Vallianatos, CN; Wu, MC | 1 |
Ardasheva, A; Biancon, G; Dura, B; Fan, R; Flavell, RA; Fu, X; Gao, Y; Gbyli, R; Halene, S; Iwasaki, A; Joshi, P; Kudo, E; Lee, V; Li, HB; Liu, C; Liu, W; Lobben, K; Nelakanti, R; Song, Y; Tebaldi, T; Teng, R; Vasic, R; Viero, G; Wang, X; Xiao, A | 1 |
Li, P; Wang, J; Xu, X; Zhang, B; Zhang, J | 1 |
George, J; Tsuchishima, M; Tsutsumi, M | 1 |
Cai, S; Ding, Y; Lan, R; Li, J; Li, Z; Liu, P; Lu, J; Wang, J; Wang, P; Xie, T; Ye, J | 1 |
Cao, W; Fu, CY; Li, XQ; Li, ZZ; Liu, WJ; Liu, XX; Qiao, YH; Sui, Y; Zhang, XW | 1 |
Dai, D; Feng, L; Jin, H; Li, J; Li, L; Shi, R; Song, P; Wang, C; Wang, X; Zhou, Q; Zhu, L | 1 |
Feng, Y; Gong, J; Guo, J; Guo, X; He, C; He, R; Jiang, J; Li, M; Li, X; Liu, J; Miao, J; Peng, F; Qin, R; Shi, C; Tian, R; Wang, M; Wei, W; Xie, Y; Xu, S; Xu, X; Yu, S; Zhang, H; Zhao, Y; Zhu, F | 1 |
Gamu, D; Gibson, WT | 1 |
Assaraf, YG; Chen, ZS; Huang, C; Jiang, J; Li, B; Xiao, H | 1 |
Chen, XZ; Dong, YH; Gao, XQ; Ju, J; Li, PF; Li, XM; Liu, CY; Liu, F; Ponnusamy, M; Qian, LL; Shan, C; Shan, PP; Wang, K; Wang, M; Wang, T; Wang, Y; Wang, YH; Yu, T; Zhai, M; Zhang, J; Zhang, YH; Zhao, XM; Zhou, LY | 1 |
Bird, A; Chhatbar, K; Cholewa-Waclaw, J; Sanguinetti, G; Shah, R | 1 |
Feng, H; Fu, D; He, L; Zhao, H | 1 |
Agnihotri, S; Bridge, T; Hawkins, C; Huang, A; Kim, B; Li, C; Milos, S; Pajovic, S; Patel, P; Phillips, L; Rakopoulos, P; Ryall, S; Sheth, J; Siddaway, R; Srikanthan, D; Yu, M | 1 |
Bartke, A; Icyuz, M; Sun, LY; Zhang, F | 1 |
Broersen, LM; Dyall, SC; Feichtinger, RG; Hageman, RJ; Kofler, B; Lotstra, S; Michael-Titus, AT; Paredes-Esquivel, U; Priestley, JV; Rhodes, M; Silva, JP; Svendsen, L; Thau-Zuchman, O; Tremoleda, JL; van Wijk, N; Verkuyl, JM | 1 |
Allen, EG; Dai, Q; Duan, R; Guo, Z; He, C; Jin, P; Kang, Y; Li, Y; Pajdzik, K; Shafik, AM; Wu, H; Yao, B; Zhang, F | 1 |
Fan, M; Li, X; Liu, Z; Pan, S; Wang, H | 1 |
Chen, JC; Hsu, CH; Kao, SH; Lin, JM; Lin, YC | 1 |
Bhagat, G; Bilbao, JR; Castellanos-Rubio, A; Garcia-Santisteban, I; Godbout, JK; Green, PH; He, C; Herrero, L; Huerta, A; Irastorza, I; Mendoza, LM; Mera, P; Olazagoitia-Garmendia, A; Rodriguez, JA; Sebastian-DelaCruz, M; Serra, D; Verdu, EF; Zhang, L | 1 |
Cao, Z; Jia, M; Li, S; Li, W; Li, Z; Liu, H; Su, M; Sun, Y | 1 |
Anderson, EN; Basso, M; Caricasole, A; Grant, RA; Hernández, IH; Lucas, JJ; Migazzi, A; Pandey, UB; Pennuto, M; Ratovitski, T; Roccuzzo, M; Ross, CA; Saudou, F; Scaramuzzino, C; Tosatto, L; Tripathy, D; Virlogeux, A; Zuccato, C | 1 |
Du, L; Xu, S; Xu, X; Yan, L; Zhang, L; Zhang, Z | 1 |
Alinari, L; Baiocchi, RA; Brown, F; Chung, JH; Courtney, LE; Kisseberth, WC; Klamer, BG; Long, M; Ozer, HG; Renaldo, KA; Scherle, P; Schlotter, S; Shilo, K; Sloan, SL; Vaddi, K; Valli, VE; Yilmaz, AS; Youssef, Y; Zhang, X | 1 |
An, Q; An, S; Chen, S; Gu, X; Li, R; Sun, C; Wang, Z | 1 |
Ding, L; Liu, D; Wang, X; Xu, H; Zhou, X; Zhu, Y | 1 |
Abisambra, JF; Alvarez, VE; Ash, PEA; Boudeau, S; Cheng, JX; Crary, JF; Cruz, AL; Emili, A; Hovde, S; Jiang, L; Kanaan, N; Kuo, MH; Kwan, J; Lei, S; Li, H; Lin, W; Maziuk, BF; Murray, ME; Petrucelli, L; Song, J; van Vliet, E; Verma, M; Wolozin, B; Yang, Z; Zhang, C; Zhao, J | 1 |
Chater-Diehl, EJ; Laufer, BI; Singh, SM | 1 |
Crabbe, JC; Gavin, DP; Guizzetti, M; Hashimoto, JG; Wiren, KM | 1 |
Bain, G; Calderon, I; Darlington, J; Evans, JF; Goulet, L; Huang, F; Hutchinson, JH; King, CD; Lai, A; Lasof, T; Lonergan, D; Ma, GL; MacKenna, DA; Nguyen, K; Prodanovich, P; Rowbottom, MW; Santini, AM; Shannon, KE | 1 |
Thomas, EA | 1 |
Bassi, S; Biagioli, M; Di Leva, F; Monziani, A; Tripathi, T | 1 |
Dragunow, M; Narayan, P | 1 |
Binó, L; Bittová, M; Drápela, S; Ešner, M; Fedr, R; Hampl, A; Hylse, O; Jaroš, J; Khirsariya, P; Kolářová, H; Kollár, P; Krejčí, L; Nikulenkov, F; Ovesná, P; Paruch, K; Samadder, P; Souček, K; Straková, N; Suchánková, T; Vaňhara, P; Vašíčková, K | 1 |
Aripovsky, A; Kulagina, T; Savina, T | 1 |
Bailis, W; Batista, PJ; Broughton, JP; Cao, G; Chang, HY; Chen, Y; Chen, YG; Duffy, EE; Flavell, RA; Kluger, Y; Kroehling, L; Li, HB; Simon, MD; Tong, J; Wang, G; Yin, Z; Zhao, J; Zhu, S | 1 |
Chen, XM; Gong, AY; Li, M; Mathy, NW; Ming, Z; Strauss-Soukup, JK; Wang, Y; Zhang, XT | 1 |
Durban, VM; Phesse, TJ; Sansom, OJ | 1 |
Borkin, D; Cierpicki, T; Grembecka, J; Kempinska, K; Klossowski, S; Malik, B; Miao, H; Shukla, S; Wang, J | 1 |
Arancio, O; Asam, K; Huber, KL; Mazzeo, A; Melideo, SL; Nicholls, RE; Pérez, E; Staniszewski, A; Stock, JB; Stock, M; Voronkov, M; Zhang, H | 1 |
Bai, J; Chen, S; Gao, J; Li, H; Pu, J; Shuai, X; Tao, K; Wang, G; Wang, J; Wu, K; Yin, Y | 1 |
Cai, W; Ding, Z; Feng, X; Hong, X; Hou, J; Huang, H; Li, Y; Qiu, X; Sha, R; Song, H; Zhang, Z; Zhao, J; Zhu, Y; Zhuo, H | 1 |
Shimura, C; Shinkai, Y; Yamada, A | 1 |
Chen, D; Cheng, L; Liu, Y; Wang, Y; Xiao, L; Yan, N; Zhang, J; Zheng, S | 1 |
Alkhayer, K; Clements, R; Freeman, E; McDonough, J; Shelestak, J; Singhal, NK | 1 |
Benevento, M; Dubos, A; Feil, R; Habibi, E; Herault, Y; Iacono, G; Kasri, NN; Kleefstra, T; Mandoli, A; Méziane, H; Riet, F; Selloum, M; Stunnenberg, HG; van Bokhoven, H; Zhou, H | 1 |
Du, J; Fang, TK; Yan, CJ | 1 |
Bao, S; Cai, W; Ding, Y; Li, M; Li, Z; Sun, Y; Xie, Q; Yin, R; Zhou, T | 1 |
Chen, Y; Jiang, R; Luo, H; Qiu, Z; Wang, Y; Yu, P; Zhu, D | 1 |
Agrawal, DK; Boosani, CS; Jiang, W | 1 |
Kaneko, S; Li, X | 1 |
Baric, RS; Dinnon, KH; Graham, RL; Gralinski, LE; Leist, SR; McAnarney, ET; Menachery, VD; Mitchell, HD; Waters, KM; Yount, BL | 1 |
Huang, M; Wang, Z; Yu, Q; Yu, X; Zeng, X; Zhang, J; Zhao, W; Zhu, M | 1 |
Absher, D; Becker, A; Benson, D; Brinkley, GJ; Buckhaults, PJ; Carobbio, F; Chen, J; Crossman, DK; Dutta, S; Emberley, E; Huang, T; Kirkman, R; Kundu, A; Kunick, C; Ogawa, S; Pan, A; Parekh, V; Poston, T; Rakheja, D; Sato, Y; Shelar, S; Shim, EH; Sudarshan, S; Tan, J; Velu, SE | 1 |
Chen, Q; Chen, S; Chen, Z; Li, J; Mi, JQ; Pandolfi, PP; Sun, H; Weng, X; Xu, J; Yan, X; Zhang, W; Zhao, C; Zhao, J; Zhu, J; Zhu, Y | 1 |
Anczurowski, M; Arrowsmith, CH; Butler, MO; Guo, T; Hirano, N; Kagoya, Y; Matsunaga, Y; Murata, K; Saijo, H; Saso, K; Sugata, K; Wang, CH | 1 |
Alahmari, B; Choi, J; Cooper, M; DiPersio, JF; Ritchey, J; Ziga, E | 1 |
Bator, E; Bilecki, W; Głowacka, U; Latusz, J; Maćkowiak, M | 1 |
Alves-Wagner, AB; Correa-Giannella, ML; Esteves, JV; Giannella-Neto, D; Machado, UF; Okamoto, MM; Yonamine, CY | 1 |
Friedman, N; Geula, S; Gillis, E; Hanna, JH; Lasman, L; Le-Trilling, VTK; Mandelboim, M; Nachshon, A; Safra, M; Schwartz, S; Soyris, C; Stern-Ginossar, N; Tai-Schmiedel, J; Trilling, M; Winkler, R | 1 |
Hwang, H; Jiang, Y; Li, Y; Wang, J; Wang, P; Wang, X; Yang, X | 1 |
Adams, PD; Birse, RT; Bodmer, R; Dall'Agnese, A; Diop, SB; Guida, MC; Mai, A; Puri, PL; Toto, PC | 1 |
Fu, Y; Repunte-Canonigo, V; Sanna, PP; Sumazin, P; Zorman, B | 1 |
Greengard, P; Hu, Z; Lin, L; Liu, T; Ma, K; Matas, E; Seo, JS; Wang, J; Wang, ZJ; Yan, Z; Yang, F; Zhang, F; Zhong, P | 1 |
Cao, Q; Chen, GJ; Cheng, J; Lin, L; Liu, A; Ma, K; Matas, E; Wang, W; Wang, X; Wang, ZJ; Wei, J; Yan, Z; Zhang, F; Zheng, Y | 1 |
Hara, A; Imakita, N; Ito, T; Kasahara, K; Kitabatake, M; Matsukawa, A; Mikasa, K; Morita-Takemura, S; Ouji-Sageshima, N; Wanaka, A | 1 |
Tamura, A | 1 |
Amin, MA; Campbell, P; Coit, P; Fox, DA; Khanna, D; Miller, S; Sawalha, AH; Tsou, PS | 1 |
Botaitis, S; Franco, R; Mantso, T; Mitsiogianni, M; Panayiotidis, MI; Pappa, A; Trafalis, DT; Vasantha Rupasinghe, HP; Zoumpourlis, V | 1 |
Gupta, R; Saha, P; Sen, N; Sen, T | 1 |
Bossenmeyer-Pourié, C; Daval, JL; Geoffroy, A; Guéant, JL; Helle, D; Pourié, G; Saber-Cherif, L; Umoret, R | 1 |
Ali, S; Chen, X; Guo, M; Huang, H; Huang, Y; Qie, S; Wang, J; Wang, S; Yu, C; Zhang, L; Zheng, X | 1 |
Hu, C; Qin, L; Qiu, K; Tan, Y; Wang, L; Wu, G | 1 |
Huang, X; Liu, L; Pan, B; Tian, J; Wang, Z; Wu, X; Zhao, W | 1 |
Caillier, SJ; Cantó, E; Condello, C; Didonna, A; Hauser, SL; Isobe, N; Mofrad, MRK; Oksenberg, JR; Shams, H; Tiwari-Woodruff, SK; Yamate-Morgan, H; Zhao, C | 1 |
Bai, Y; Cheng, J; Liu, H; Tao, J; Xiao, Q; Zhao, Q; Zhu, Y | 1 |
Lee, IS; Sang Cho, K; Song, B | 1 |
Amini, B; Bergsagel, PL; Davis, RE; Gagel, RF; He, J; Hou, J; Koh, SP; Lee, HC; Li, Z; Lin, P; Liu, H; Liu, Z; Navone, NM; Orlowski, RZ; Starbuck, MW; Tam, BT; Tong, Q; Wang, Z; Xiao, M; Yang, J; Yi, Q; Young, KH; Zhang, Y; Zhong, Y | 1 |
Chen, J; Lin, N; Lu, Y; Xu, M; Xu, R; Yao, Z; Yuan, L; Zhou, S; Zou, X | 1 |
Jiang, H; Khodadadi-Jamayran, A; Shah, K; Yang, Z | 1 |
Cheng, L; Dong, Z; Gong, H; Li, KE; Shu, S; Shu, X | 1 |
Hewitson, TD; Holt, SG; Samuel, CS; Smith, ER; Wigg, B | 1 |
Han, R; Wu, Q; Xiu, R; Yuan, X; Zhang, H | 1 |
Baeza, I; Claus, SP; de Castro, NM; de la Fuente, M; Yaqoob, P | 1 |
Contestabile, A; Sintoni, S | 1 |
Monti, B | 1 |
Monti, B; Peña-Altamira, LE; Polazzi, E | 1 |
Deng, YQ; Dong, H; Leng, QB; Li, SH; Li, XF; Qin, CF; Qin, ED; Shi, PY; Wang, HJ; Wang, XY; Xie, X; Ye, Q; Zhang, B; Zhao, H; Zhu, SY; Zuest, R | 1 |
Berger, M; Hoebe, K; Kono, DH; Lawson, BR; Manenkova, Y; Tardif, V; Theofilopoulos, AN; Yuan, C; Zuo, JP | 1 |
Aggarwal, T; Casci, I; Fackelmayer, FO; Lanson, NA; Maltare, A; Milioto, C; Monaghan, J; Pandey, UB; Pennuto, M; Scaramuzzino, C | 1 |
Donaghy, J; Horowitz, JC; Huang, SK; Peters-Golden, M; Przybranowski, S; Scruggs, AM; White, ES; Zaslona, Z | 1 |
Akula, MK; Bergo, MO; Fong, LG; Ibrahim, MX; Liu, M; Sayin, VI; Young, SG | 1 |
Ghosh, S; Liu, B; Wang, Z; Zhang, L; Zheng, H; Zhou, Z | 1 |
Chen, W; Hu, J; Hu, S; Huang, LY; Jiang, X; Wang, YM; Xiao, Y; Xu, GY; Zhang, HH; Zhou, YL | 1 |
Blom, HJ; Castro, R; de Vriese, AS; Esse, R; Florindo, C; Imbard, A; Rocha, MS; Smulders, YM; Tavares de Almeida, I; Teerlink, T | 1 |
Davidge, ST; Hardy, DB; Morton, JS; Osumek, JE; Revesz, A | 1 |
Cabezas-Herrera, J; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L | 1 |
Li, L; Rong, R; Wang, J; Xu, M; Zhu, T | 1 |
Arning, E; Bottiglieri, T; Gibson, KM; Vogel, KR; Wasek, BL | 1 |
Bame, M; Brusilow, WS; Grier, RE; Needleman, R | 1 |
Chen, P; Chen, Y; He, Z; Peng, H; Zeng, H; Zhang, H; Zhang, Y | 1 |
Abdel-Wahab, O; Aburatani, H; Enomoto, Y; Harada, H; Harada, Y; Heuser, M; Inoue, D; Isobe, M; Izawa, K; Kagiyama, Y; Kawabata, KC; Kimura, H; Kitamura, T; Kitaura, J; Levine, RL; Maehara, A; Nakahara, F; Nishimura, K; Ochiya, T; Oki, T; Thol, F; Togami, K; Tsuchiya, A; Uchida, T | 1 |
Kim, Y; Kowall, NW; Lee, J; Park, E; Ryu, H | 1 |
Boemke, W; Francis, RC; Höhne, C; Neubert, F; Pickerodt, PA; Swenson, ER; Telalbasic, S | 1 |
Blom, HJ; Castro, R; Davids, M; Esse, R; Florindo, C; Gupta, S; Imbard, A; Kruger, WD; Quinlivan, EP; Tavares de Almeida, I; Teerlink, T | 1 |
Antignano, F; Arrowsmith, CH; Braam, MJ; Burrows, K; Chenery, AL; Fung, TC; Gold, MJ; Han, JM; Hughes, MR; Kron, KJ; Levings, MK; Lupien, M; McNagny, KM; Min, PH; Oudhoff, MJ; Penrod, NM; Rossi, FM; Wang, SK; Zaph, C | 1 |
Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C | 1 |
Baek, JH; Rubinstein, M; Scheuer, T; Trimmer, JS | 1 |
Aparicio, SA; Berg, T; Bilenky, M; Chang, H; Cheng, SW; Gascoyne, RD; Hirst, M; Humphries, RK; Lai, CK; Lai, D; Lee, S; Lim, E; Marra, MA; Morin, GB; Morin, RD; Mungall, AJ; Oellerich, T; Rosten, P; Salmi, A; Schoeler, N; Serve, H; Thoene, S; Umlandt, P; Wee, T; Yap, D; Yue, L | 1 |
Chen, J; Dou, X; Li, S; Qian, Y; Song, Z; Xia, Y; Zhang, X | 1 |
Barbash, O; Butte, AJ; Dhanak, D; Garcia, BA; Gozani, O; Huddleston, M; Jansen, PW; Khatri, P; Kruger, RG; Liu, S; Mazur, PK; Reynoird, N; Sage, J; Tummino, PJ; Van Aller, GS; Vermeulen, M; Wilkinson, AW | 1 |
Gao, K; Liu, Z; Rong, H; Wan, Q; Wang, G; Wang, H; Wang, X; Wu, M | 1 |
Charlton, CG; Dent, L; Griffin, B; King, J; Mackey, V; Muthian, G; Smith, ML | 1 |
Dawn, B; Elias, HK; Malik, AB; Rajasingh, J; Rajasingh, S; Simpson, AD; Sundivakkam, PK; Thangavel, J; Vogel, SM; Xuan, YT | 1 |
Basurto-Islas, G; Blanchard, J; Fernandez, JR; Iqbal, K; Stock, JB; Stock, M; Tung, YC; Voronkov, M; Zhang, S | 1 |
Emery, R; Hodges, SJ; Oguz, C; Pitsillides, AA; Soper, RJ | 1 |
Cao, JL; Peng, YN; Tang, LH; Wang, Y; Yan, M; Yu, LN; Zhou, XL | 1 |
Cai, C; Chai, R; He, Y; Li, H; Sun, S; Yu, H | 1 |
Kuang, D; Liu, J; Liu, T; Wu, Y; You, L; Zheng, Y | 1 |
Eissenberg, JC; Florens, L; Gao, X; Herz, HM; Jackson, J; Morgan, M; Rickels, R; Shilatifard, A; Swanson, SK; Washburn, MP | 1 |
Cui, W; Kong, L; Li, X; Luo, M; Miao, L; Tan, Y; Wu, H; Xu, F; Zhou, S | 1 |
Agrawal, R; Gomez-Pinilla, F; Tyagi, E; Ying, Z; Zhuang, Y | 1 |
Bearss, J; Gajiwala, S; Janat-Amsbury, M; Sharma, S; Sorna, V; Theisen, ER | 1 |
Berglund, JA; Coonrod, LA; Copperman, J; deLorimier, E; Guenza, MG; Reister, EE; Sharma, K; Taber, A; Todd, PK | 1 |
Huang, W; Ling, W; Peng, C; Xia, M; Xiao, Y; Zhang, J | 1 |
García, A; Hinrichsen, LI; Lamas, MC; Leonardi, D; Vasconi, MD | 1 |
Albrecht, BK; Arora, S; Audia, JE; Balasubramanian, S; Bradley, WD; Bryant, BM; Busby, J; Campbell, R; Cantone, N; Cook, AS; Cummings, RT; Dakin, LA; Daniels, DL; Garapaty-Rao, S; Gehling, VS; Harmange, JC; Hatton, C; Iyer, P; Méndez, J; Nasveschuk, CG; Normant, E; Trojer, P; Vaswani, RG; Williamson, KE; Yuan, CC; Zhao, F | 1 |
Georgieff, MK; Kennedy, BC; Lien, YC; Simmons, RA; Tran, PV | 1 |
Cai, Q; Chen, X; Dong, W; Gu, P; He, W; Huang, J; Lin, T; Wang, B; Xie, W; Xie, Y; Zhong, G | 1 |
Ozanne, SE | 1 |
Berger, H; Chin, KC; Gingras, AR; Ginhoux, F; Gunawan, M; Guo, T; La Win, MK; Li, LY; Loh, JT; Neo, WH; Ng, LG; See, PC; Shochat, SG; Su, IH; Sze, SK; Venkatesan, N; Wong, JF; Yamazaki, S; Yau, YH | 1 |
Fan, Z; Jia, Z; Liu, D; Song, J; Wang, J; Wang, L; Wang, S; Wang, Y; Yang, D | 1 |
DeSimone, J; Ibanez, V; Jagadeeswaran, R; Kouznetsova, T; Lavelle, D; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
Fan, Y; Fang, J; Han, S; He, X; Heng, D; Li, L; Liu, W; Peng, B; Wang, Z; Yin, J | 1 |
Cadet, JL; Godino, A; Jayanthi, S | 1 |
Nachman, PH; Pendergraft, WF | 1 |
Chen, W; Hu, S; Jiang, GQ; Jiang, X; Wei, J; Xu, GY; Zhang, HH; Zhou, YL; Zhu, H | 1 |
Aguilar, DD; Carless, MA; Giuffrida, A; Lodge, DJ; Neary, JL; Perez, SM | 1 |
Bollag, WB; Choi, JH; Figueroa, M; Li, X; Liu, F; Liu, K; Lu, C; Nayak-Kapoor, A; Oberlies, NH; Paschall, AV; Pearce, C; Yang, D | 1 |
Aldámiz-Echevarría, L; Andrade, F; Aspichueta, P; Barbier-Torres, L; Beraza, N; Falcon-Perez, JM; Fernandez, ML; Fernández-Ramos, D; Fernandez-Tussy, P; García-Monzón, C; García-Rodríguez, JL; Juan, VG; Lage-Medina, S; Lopitz-Otsoa, F; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Martínez-Uña, M; Mato, JM; Varela-Rey, M; Wagner, C; Woodhoo, A; Zubiete-Franco, I | 1 |
Kitanaka, C; Kurachi, H; Kuramoto, K; Nagase, S; Ohta, T; Okada, M; Sakaki, H; Seino, M; Seino, S; Suzuki, S; Takeda, H; Watarai, H | 1 |
Baek, SH; Bhin, J; Hwang, D; Kim, C; Kim, D; Kim, Y; Koh, GY; Lee, H; Lee, J; Nam, HJ; Park, DY; Park, SW; Yu, YS | 1 |
Agarwal, S; Badeaux, AI; Brookes, E; Chen, C; Egan, B; Gu, L; Ito, H; Iwase, S; Kasza, T; Kwan, KY; Lin, G; Sartor, MA; Shi, Y; Thompson, A; Tomassy, GS; Vallianatos, CN; Xu, J | 1 |
Bigaud, E; Corrales, FJ | 1 |
Boeynaems, S; Bogaert, E; Callaerts, P; Cruts, M; Cuijt, I; De Baets, G; Gijselinck, I; Gitler, AD; Jovičić, A; Michiels, E; Robberecht, W; Rousseau, F; Scheveneels, W; Schymkowitz, J; Sieben, A; Steyaert, J; Van Broeckhoven, C; Van Damme, P; Van Den Bosch, L; Verstrepen, KJ | 1 |
Bernstein, D; Chang, CP; Chen, CH; Chen, HS; Cheng, HL; Cheng, W; Drakos, SG; Ghetti, A; Han, P; Hang, CT; Li, DY; Li, W; Lin, CH; Quertermous, T; Shang, C; Wong, J; Xiong, Y; Yang, J; Zhao, M | 1 |
Bhatti, B; Idris, MM; Kumar, A; Mandal, KK; Meena Lakshmi, MG; Meghah, V; Narasimha Murthy, ChL; Poruri, A; Purushothaman, S; Sarath Babu, N; Saxena, S | 1 |
Lei, PJ; Li, L; Li, YM; Wang, HY; Wei, G; Wu, M; Ye, M; Zhang, X; Zhao, J; Zhao, QY; Zheng, JY | 1 |
Hwangbo, MH; Kim, IK; Lee, HA; Park, KM; Seok, YM | 1 |
Alberry, BL; Castellani, CA; Chater-Diehl, EJ; Laufer, BI; Singh, SM | 1 |
Cheng, SY; Fu, L; Gao, D; Wu, H; Zhang, L; Zhao, Y | 1 |
Bae, GU; Bang, SY; Han, JW; Jeon, YJ; Kozma, SC; Lee, J; Lee, MG; Lee, SJ; Nam, KH; Park, EK; Park, JW; Rhie, JW; Thomas, G; Um, SH; Yi, SA; Yoo, JH; You, JS | 1 |
Buechele, C; Cleary, ML; Duque-Afonso, J; Gozani, O; Hansen, L; Huang, M; Ikenouye, L; Klein, BJ; Kutateladze, TG; Li, Q; Majeti, R; Martin, GM; Onishi, M; Schneidawind, D; Shen, J; Wong, SH; Zhu, F; Zhu, L | 1 |
Judson, RN; Kast, J; Liu, DY; Rossi, FM; Zhang, RH | 1 |
Agger, K; Helin, K; Johansen, JV; Kooistra, SM; Miyagi, S; Pedersen, MT | 1 |
Guo, G; Ramadoss, S; Wang, CY | 1 |
Fang, Y; Gao, J; Guo, X; Huang, M; Liu, C; Qi, X; Ruan, H; Shen, W; Xu, M; Zheng, J | 1 |
Cho, H; Choi, D; Ho, WK; Jeon, D; Jeong, MH; Jung, CY; Jung, S; Kang, JS; Kang, K; Kim, H; Kim, HJ; Kim, KR; Kim, SH; Kim, ST; Koh, J; Koo, SH; Lee, SY; Park, JM; Park, SK; Sohn, JW; Vuong, TA; Yang, H | 1 |
Alisch, RS; Chen, L; Chopra, P; Jin, P; Keleş, S; Li, S; Madrid, A; Papale, LA; Zhang, Q | 1 |
Kamejima, S; Ohkido, I; Okabe, M; Tatsumi, N; Uchiyama, T; Waku, T; Yokoo, T; Yokoyama, K | 1 |
Cackowski, FC; Decker, AM; Franceschi, RT; Jung, Y; Lee, E; Li, Y; Pienta, KJ; Taichman, RS; Wang, J; Yumoto, K | 1 |
Guo, W; Jia, Y; Jiang, Y; Sun, Y; Tian, J; Wang, Y; Yang, A; Yang, X; Zhang, H; Zhu, G | 1 |
Kong, Y; Sun, Q; Xu, X; Yang, X; Zhan, Y; Zhang, J | 1 |
Ainslie, KM; Amici, SA; Bachelder, EM; Baiocchi, RA; Green, PL; Guerau-de-Arellano, M; Jablonski, KA; Karkhanis, V; Li, C; Li, L; Panfil, AR; Peine, K; Savardekar, H; Webb, LM; Zhou, W | 1 |
Dai, RP; Hu, ZL; Huang, FL; Huang, YQ; Li, CQ; Li, F; Qiao, XQ; Wang, HT; Zhang, WJ | 1 |
Azadi, P; Baker, S; Black, I; Brown, N; Davies, MR; Donohue, N; Heiss, C; Kaye, PM; Kintz, E; van der Woude, M | 1 |
Chen, D; Cong, G; Hou, J; Huang, H; Jia, S; Jin, P; Wang, K; Yan, N; Yan, R; Zhang, N | 1 |
Akimoto, Y; Beltcheva, O; Fukutomi, T; Hada, I; Ito, Y; Katada, T; Katayama, K; Kimura, T; Kudo, A; Kurayama, R; Nishibori, Y; Suehiro, J; Takahashi, S; Tryggvason, K; Yan, K | 1 |
Dai, X; Fang, F; Fang, M; Qi, X; Xu, H; Xu, Y; Yu, L | 1 |
Gorelik, G; Jeffries, M; Johnson, K; Knowlton, N; Lu, Q; Osban, J; Ray, D; Richardson, B; Sawalha, AH; Webb, R | 1 |
Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN | 1 |
Barbosa-Morais, NL; Conboy, CM; Fisher, EM; Odom, DT; Schmidt, D; Tavaré, S; Tybulewicz, VL; Vanes, L; Wilson, MD | 1 |
Cheung, N; So, CW; Yeung, J; Zeisig, BB | 1 |
Bardag-Gorce, F; Dedes, J; French, BA; French, SW; Li, J; Oliva, J | 1 |
Anilkumar, N; Cave, AC; Kentish, JC; Layland, J; Marshall, M; Shah, AM; Walker, SJ | 1 |
Deussen, A; Henle, T; Herrmann, M; Pexa, A; Taban-Shomal, O | 1 |
Brody, SL; Cannon, CL; Capps, GH; Hindi, KM; Hogue, LA; Ibricevic, A; Kascatan-Nebioglu, A; Vajravelu, RK; Walter, MJ; Youngs, WJ | 1 |
Kodadek, TJ; Kumar, A; LaPlant, Q; Nestler, EJ; Renthal, W; Sikder, D; Wilkinson, MB; Xiao, G | 1 |
Allen, RM; Carson, WF; Cavassani, KA; Coelho, AL; Corsa, CA; Dou, Y; Hogaboam, CM; Ishii, M; Kunkel, SL; Li, X; Liu, T; Lukacs, NW; Wen, H | 1 |
de Jong, PH; Glansbeek, HL; Hagenaars, N; Heldens, JG; Hennink, WE; Jiskoot, W; Mastrobattista, E; Mooren, I; van den Bosch, H; Verheul, RJ | 1 |
Delgado, JM; Jiménez-Capdeville, ME; Ortiz-Pérez, D; Ríos, R; Santoyo, ME; Zarazúa, S | 1 |
Kuroda, Y; Moritomo, H; Murase, T; Okada, K; Okamoto, M; Tanaka, H; Temporin, K; Yoshikawa, H | 1 |
Bardag-Gorce, F; French, BA; French, SW; Li, J; Lu, SC; Oliva, J | 1 |
Costa, E; Davis, JM; Guidotti, A; Kadriu, B; Pibiri, F; Tueting, P; Veldic, M | 1 |
Cavallaro, RA; Fuso, A; Nicolia, V; Scarpa, S | 1 |
Chen, Y; Fang, Y; Jang, Y; Wei, L; Wu, X; Yan, G; Yi, L; Zhou, X | 1 |
Benbrahim-Tallaa, L; Lunn, R; Sams, RL; Tokar, EJ; Waalkes, MP; Ward, JM | 1 |
Baldwin, KM; Bodell, PW; Haddad, F; Jiang, W; Qin, AX | 1 |
Pertino, MW; Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C | 1 |
Bui, PH; Handforth, A; Hankinson, O; Homanics, GE; Quesada, A | 1 |
Agellon, LB; Li, Z; Vance, DE | 1 |
Braithwaite, SP; Chao, Y; Chen, W; Feng, X; Fernandez, JR; Grosso, H; Im, JY; Junn, E; Lee, KW; Masliah, E; Mouradian, MM; Ray, N; Sonsalla, PK; Stock, JB; Voronkov, M | 1 |
Belshaw, N; Hindmarsh, A; Johnson, IT; Mehta, S; Rhodes, M | 1 |
Bertolo, RF; Brophy, JD; MacKay, DS; McBreairty, LE; McGowan, RA | 1 |
Cameron, CE; Eshghi, A; Frank, A; Haake, DA; Pinne, M; Zuerner, RL | 1 |
Allen, RH; Greiner, LS; Jiang, H; Maclean, KN; Stabler, SP | 1 |
Chen, JK; Cheung, P; Gozani, O; Ishibe-Murakami, S; Kuo, AJ; Patel, DJ; Song, J; Yamazoe, S | 1 |
Ilnytskyy, S; Kolb, B; Kovalchuk, A; Kovalchuk, O; Lowings, M; Muhammad, A; Rodriguez-Juarez, R | 1 |
Cvetkovic, T; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Sokolovic, D; Stevanovic, I; Stojanovic, I | 1 |
Baker, SJ; Becksfort, J; Bouffet, E; Chalhoub, N; Chen, X; Cohn, R; Curley, N; Ding, L; Dooling, DJ; Downing, JR; Easton, J; Ellison, DW; Finkelstein, D; Fulton, LL; Fulton, RS; Gajjar, A; Gilbertson, RJ; Gupta, P; Gururangan, S; Hassall, T; Hedlund, E; Hong, X; Huether, R; Kawauchi, D; Kranenburg, TA; Kriwacki, R; Lau, CC; Li, S; Lin, T; Lu, C; Ma, J; Mardis, ER; Ochoa, K; Onar-Thomas, A; Parker, M; Paugh, S; Phoenix, TN; Pounds, S; Robinson, G; Roussel, MF; Rusch, M; Thiruvenkatam, R; Vadodaria, B; Wang, J; Wei, L; Wilson, RK; Wu, G; Zhang, J; Zhao, D; Zhu, X | 1 |
Halsted, CH; Medici, V | 1 |
Abarinov, EV; Allen, RH; Ash, JA; Caudill, MA; Field, MS; Malysheva, OV; Shields, KS; Stabler, SP; Stover, PJ; Strupp, BJ | 1 |
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT | 1 |
Chan, JP; Festenstein, R; Goula, AV; Merienne, K; Stys, A; Trottier, Y | 1 |
Bollag, G; Bornman, WG; Davies, MA; Dayyani, F; Desai, J; Gallick, GE; Gopal, YN; Jiang, ZQ; Kopetz, S; Lemos, R; Mao, M; Mariadason, JM; Mills, GB; Powis, G; Tang, XM; Tian, F; Tsao, CC; Wistuba, II | 1 |
Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L | 1 |
Burda, J; Martín de la Vega, C; Salinas, M; Toledo Lobo, MV | 1 |
Demidem, A; Madelmont, JC; Morvan, D; Papon, J | 1 |
Ji, C; Kaplowitz, N | 1 |
Moore, AR | 1 |
Seed, MP | 1 |
Chai, HB; Chávez, D; Cordell, GA; Díaz, F; Fairchild, CR; Farnsworth, NR; Kardono, LB; Kinghorn, AD; Lee, D; Mi, Q; Pezzuto, JM; Riswan, S; Tan, GT; Wild, R | 1 |
Albanes, D; Glynn, SA | 1 |
Arnhold, T; Caudill, MA; Collins, MD; Fahr, SH; Henning, SM; Mao, GE; Nau, H; Santos-Guzmán, J; Swendseid, ME; Wagner, C; Wang, JC | 1 |
Buettner, R; Corzilius, L; Doerfler, W; Dorn, A; Hilger-Eversheim, K; Hohlweg, U; Hösel, M; Niemann, A; Remus, R; Schmitz, B; Schramme, A; Webb, D | 1 |
Martin, CC; O'Brien, RM; Oeser, JK | 1 |
Bibby, MC; Blackburn, A; Lucock, MD; Nicolaou, A | 1 |
Beal, MF; Browne, SE; Choi, DK; Ferrante, RJ; Gardian, G; Gregorio, J; Klivenyi, P; Kubilus, JK; Langley, B; Ratan, RR; Ryu, H | 1 |
Costa, E; Davis, J; Dong, E; Doueiri, MS; Grayson, DR; Guidotti, A; Pinna, G; Rodriguez-Menendez, V; Tremolizzo, L; Tueting, P | 1 |
Chen, LY; Du, YM; Liu, SQ; Peng, H; Qiu, B | 1 |
Braig, M; Dörken, B; Jenuwein, T; Lee, S; Loddenkemper, C; Peters, AH; Rudolph, C; Schlegelberger, B; Schmitt, CA; Stein, H | 1 |
Berton, O; Kumar, A; Nestler, EJ; Neve, RL; Renthal, W; Tsankova, NM | 1 |
Bhattacharya, SK; Bonilha, VL; Crabb, JS; Crabb, JW; Gu, X; Takahara, H | 1 |
Aldape, K; Black, PM; Chakravarti, A; Erkkinen, MG; Gilbert, MR; Loeffler, JS; Mehta, M; Nestler, U; Stupp, R | 1 |
Bucana, CD; Chakravarty, G; El-Naggar, AK; Jasser, SA; Kim, S; Myers, JN; Santillan, AA; Wang, Z; Yazici, YD; Younes, MN | 1 |
Bundle, SF; Carson, JP; McGill, BE; Thaller, C; Yaylaoglu, MB; Zoghbi, HY | 1 |
Harris, MJ; Juriloff, DM | 1 |
Cmejla, R; Cmejlova, J; Elleder, M; Man, P; Myslivcova, D; Petrak, J; Vulpe, CD; Vyoral, D | 1 |
Cormier, K; Del Signore, SJ; Ferrante, RJ; Goldstein, DR; Goodrich, S; Hagerty, SW; Luthi-Carter, R; Markey, AL; Matson, S; Ryu, H; Smith, K; Soh, BY; Stack, EC | 1 |
Muriel, P; Perez-Alvarez, V; Rivera, H; Shibayama, M; Tsutsumi, V | 1 |
Ghosh, AK; Varga, J | 1 |
Alberto, JM; Blaise, S; Bronowicki, JP; Delabar, JM; Guéant, JL; Hamelet, J; Janel, N; Noll, C | 1 |
Allgood, JC; Dillehay, DL; Merrill, AH; Moody, SJ; Morales, PR; Pallas, DC; Pruett, S; Symolon, H | 1 |
Amidi, F; Bardag-Gorce, F; Dedes, J; Fraley, S; French, B; French, SW; Li, J; Oliva, J; Villegas, J | 1 |
Prewitt, AK; Westberry, JM; Wilson, ME | 1 |
Bezard, E; Brotchie, JM; Fox, SH; Hallett, PJ; Lubin, FD; Nicholas, AP; Ravenscroft, P; Standaert, DG; Sweatt, JD; Vattem, P; Zhou, S | 1 |
DeSimone, J; Heller, P | 1 |
Dinn, JJ; McCann, S; Reed, B; Scott, JM; Weir, DG; Wilson, P | 1 |
Limas, CJ | 1 |
Bottiglieri, T; Hyland, K; Reynolds, EH | 1 |
Berns, A; Breuer, ML; Hershfield, MS; Migchielsen, AA; Ossendorp, F; te Riele, H; Toutain, S; Valerio, D; van Roon, MA; Zurcher, C | 1 |
Iwai, H | 1 |
Adam-Rodwell, G; Morse, MA; Stoner, GD | 1 |
Counts, JL; Goodman, JI | 1 |
Andrews, JS; de Boer, T; Gibson, S; Plate, R; Plaum, MJ; Rae, DR | 1 |
Hoogeveen, AT; Oostra, BA | 1 |
Kitchin, KT | 1 |
Arning, E; Bottiglieri, T; Dayal, S; Faraci, FM; Heistad, DD; Lentz, SR; Maeda, N; Malinow, MR; Sigmund, CD | 1 |
Finnell, RH; Gelineau-van Waes, J | 1 |
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN | 1 |
Campbell, C; Hillman, RS; McGuffin, R | 1 |
Metz, J | 1 |
Espina, N; Garro, AJ; McBeth, D; Wang, SL; Wu-Wang, CY | 1 |
Monk, M | 1 |
Gerhardt, KO; Katz, ML | 1 |
Joosten, LA; Schalkwijk, J; van de Putte, LB; van den Berg, WB | 1 |
Chanarin, I; Deacon, R; Green, R; Lumb, M; Perry, J; Purkiss, P | 1 |
Goldsworthy, TL; Hanigan, MH; Pitot, HC | 1 |
De Bault, LE; Desai, LS; Foley, GE; Morrissey, G | 1 |
Nagai, Y; Nakano, K | 1 |
Jervis, HR; Sheahan, DG; Sprinz, H; Takeuchi, A | 1 |
Ryan, SF | 1 |
Carlo, IA; Kottke, BA; Subbiah, MT; Weaver, KM | 1 |
38 review(s) available for isomethyleugenol and Disease Models, Animal
Article | Year |
---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
Identification of methylation-regulated genes modulating microglial phagocytosis in hyperhomocysteinemia-exacerbated Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Humans; Hyperhomocysteinemia; Methylation; Mice; Mice, Transgenic; Microglia; Phagocytosis | 2023 |
Metabolism of N-nitrosodimethylamine, methylation of macromolecules, and development of hepatic fibrosis in rodent models.
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Disease Susceptibility; Fibroblasts; Fibrosis; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Macromolecular Substances; Methylation; Rodentia | 2020 |
Reciprocal skeletal phenotypes of PRC2-related overgrowth and Rubinstein-Taybi syndromes: potential role of H3K27 modifications.
Topics: Acylation; Animals; Disease Models, Animal; Histones; Humans; Lysine; Methylation; Mice; Polycomb-Group Proteins; Rubinstein-Taybi Syndrome | 2020 |
Surmounting cancer drug resistance: New insights from the perspective of N
Topics: Adenosine; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Disease Models, Animal; DNA Damage; DNA Repair; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Methylation; Neoplasms; Protein Kinase Inhibitors; RNA Processing, Post-Transcriptional; Treatment Outcome; Tumor Microenvironment | 2020 |
Serine, glycine and one‑carbon metabolism in cancer (Review).
Topics: Animals; Antineoplastic Agents; Carbon; Carcinogenesis; Disease Models, Animal; Glycine; Humans; Metabolic Networks and Pathways; Methylation; Mice; Neoplasms; Oxidation-Reduction; Serine; Tumor Microenvironment; Warburg Effect, Oncologic | 2021 |
Changes to histone modifications following prenatal alcohol exposure: An emerging picture.
Topics: Acetylation; Alcohol Drinking; Animals; Brain; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Fetal Alcohol Spectrum Disorders; Gestational Age; Histocompatibility Antigens; Histone Acetyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Maternal Exposure; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational | 2017 |
Histone Posttranslational Modifications in Schizophrenia.
Topics: Acetylation; Amino Acid Sequence; Animals; Brain Chemistry; Disease Models, Animal; Electroconvulsive Therapy; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Humans; Lymphocytes; Methylation; Mice; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Schizophrenia; Ubiquitination | 2017 |
Epigenetics of Huntington's Disease.
Topics: Acetylation; Animals; Cell Line; Chromatin Assembly and Disassembly; Clinical Trials as Topic; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Methylation; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Polycomb-Group Proteins; Protein Processing, Post-Translational; RNA, Untranslated | 2017 |
Alzheimer's Disease and Histone Code Alterations.
Topics: Acetylation; Alzheimer Disease; Animals; Apolipoprotein E4; Brain Chemistry; Disease Models, Animal; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Mutation; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Risk Factors | 2017 |
Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models.
Topics: Animals; Apoptosis; CRISPR-Cas Systems; Disease Models, Animal; Epithelium; Genes, Tumor Suppressor; Humans; Intestinal Neoplasms; Methylation; Mice; Mice, Transgenic; Neoplasms, Experimental; Neoplastic Stem Cells; Oncogenes; Signal Transduction; Stem Cells | 2017 |
Cell‑specific histone modifications in atherosclerosis (Review).
Topics: Acetylation; Animals; Atherosclerosis; Disease Models, Animal; Histones; Humans; Methylation; Plaque, Atherosclerotic; Protein Processing, Post-Translational | 2018 |
[Intracellularly Degradable Polyrotaxanes for Therapeutic Applications].
Topics: Animals; Autophagy; beta-Cyclodextrins; Cholesterol; Cyclodextrins; Disease Models, Animal; Drug Carriers; Drug Design; Fibroblasts; Humans; Hydrogen-Ion Concentration; Lysosomes; Macromolecular Substances; Methylation; Mice; Niemann-Pick Diseases; Poloxamer; Rotaxanes | 2019 |
Neurodevelopmental disorders with epigenetic dysregulation and
Topics: Acetylation; Animals; Disease Models, Animal; Drosophila; Epigenesis, Genetic; Epigenomics; Histones; Humans; Methylation; Neurodevelopmental Disorders | 2019 |
Histone acetylation in neurodevelopment.
Topics: Acetylation; Animals; Autistic Disorder; Disease Models, Animal; Female; Hippocampus; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Male; Methylation; Nerve Tissue Proteins; Neurogenesis; Neurons; Pregnancy; Protein Processing, Post-Translational; Teratogenesis | 2013 |
Histone post-translational modifications to target memory-related diseases.
Topics: Acetylation; Animals; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; Histones; Humans; Memory Disorders; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Nootropic Agents; Phosphorylation; Protein Processing, Post-Translational | 2013 |
Histone post-translational modifications in Huntington's and Parkinson's diseases.
Topics: Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Humans; Huntington Disease; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination | 2013 |
The role of microRNAs in diabetic nephropathy.
Topics: Acetylation; Animals; Chromatin; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dogs; Epigenesis, Genetic; Epigenomics; Histones; Humans; Inflammation; Kidney; Lysine; Methylation; Mice; Mice, Transgenic; MicroRNAs; Rats | 2014 |
Epigenetic signatures of obesity.
Topics: Animals; Carbohydrates; Chromatin; Chromosomal Proteins, Non-Histone; Diet; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Male; Methylation; Mice; Obesity; Spermatozoa; Transcription, Genetic; Triglycerides | 2015 |
Epigenetic landscape of amphetamine and methamphetamine addiction in rodents.
Topics: Acetylation; Amphetamine; Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Histone Deacetylases; Histones; Humans; Methamphetamine; Methylation; Mice; Neuronal Plasticity; Proto-Oncogene Mas; Rats | 2015 |
Recent pathogenetic advances in ANCA-associated vasculitis.
Topics: Alleles; Animals; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; Autoantigens; Biomarkers; Disease Models, Animal; Epigenesis, Genetic; Ethnicity; Forecasting; Genetic Predisposition to Disease; Genome-Wide Association Study; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lymphocyte Subsets; Methylation; Myeloblastin; Peroxidase; Phenotype; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational | 2015 |
Cancer in experimental animals exposed to arsenic and arsenic compounds.
Topics: Animals; Arsenic; Arsenicals; Carcinogens; Disease Models, Animal; Female; Humans; Male; Methylation; Mice; Mice, Inbred Strains; Neoplasms; Rats; Rats, Inbred Strains | 2010 |
Folate, alcohol, and liver disease.
Topics: Absorption; Alcohol Drinking; Animals; Antioxidants; Disease Models, Animal; Epigenesis, Genetic; Ethanol; Folic Acid; Folic Acid Deficiency; Gene Expression; Humans; Intestine, Small; Liver; Liver Diseases, Alcoholic; Methionine; Methylation | 2013 |
Pleural models of inflammation: immune and nonimmune.
Topics: Animals; Arthritis; Arthus Reaction; Calcium Pyrophosphate; Carrageenan; Cattle; Crystallization; Disease Models, Animal; Durapatite; Inflammation; Male; Methylation; Mice; Models, Animal; Pleural Effusion; Pleurisy; Rats; Rats, Wistar; Serum Albumin, Bovine; Uric Acid | 2003 |
The assessment of inflammation, cartilage matrix, and bone loss in experimental monoarticular arthritis of the rat.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biomarkers; Bone Resorption; Cartilage, Articular; Cattle; Disease Models, Animal; Extracellular Matrix; Glycosaminoglycans; Immunosuppressive Agents; Inflammation; Male; Methylation; Models, Animal; Mycobacterium tuberculosis; Patella; Proteoglycans; Rats; Rats, Inbred Lew; Rats, Wistar; Rheumatic Diseases; Serum Albumin, Bovine; Species Specificity; Zymosan | 2003 |
Folate and cancer: a review of the literature.
Topics: Animals; Disease Models, Animal; Folic Acid; Folic Acid Deficiency; Humans; Methylation; Neoplasms; Risk Factors | 1994 |
Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects.
Topics: Actins; Animals; Apoptosis; Cell Cycle; Disease Models, Animal; Female; Humans; Methylation; Mice; Mice, Mutant Strains; Mutation; Neural Tube Defects; Spina Bifida Occulta | 2007 |
The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis.
Topics: Acetylation; Acetyltransferases; Animals; Collagen; Disease Models, Animal; Drug Antagonism; E1A-Associated p300 Protein; Epigenesis, Genetic; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Interferon-gamma; Methylation; Mice; Models, Biological; Phosphorylation; PPAR gamma; Protein Structure, Tertiary; Smad3 Protein; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2007 |
5-Azacytidine and fetal hemoglobin.
Topics: Adult; Anemia, Sickle Cell; Animals; Azacitidine; Carcinogens; Disease Models, Animal; DNA; Fetal Hemoglobin; Gene Expression Regulation; Humans; Male; Methylation; Middle Aged; Papio; Thalassemia | 1984 |
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
Topics: AIDS Dementia Complex; Animals; Brain Diseases; Dementia; Disease Models, Animal; Epilepsy; Humans; Metabolism, Inborn Errors; Methotrexate; Methylation; Multiple Sclerosis; Neurotransmitter Agents; Parkinson Disease; Receptors, Neurotransmitter; S-Adenosylmethionine; Spinal Cord Diseases | 1994 |
Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion.
Topics: Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; DNA; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Methylation; Mice | 1995 |
Animal model for fragile X syndrome.
Topics: Animals; Carrier Proteins; Codon; Cytosine; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Guanine; Humans; Intellectual Disability; Methylation; Mice; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Biosynthesis; Repetitive Sequences, Nucleic Acid; RNA-Binding Proteins; RNA, Messenger | 1997 |
Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites.
Topics: Animals; Arsenic; Cell Division; Disease Models, Animal; DNA Methylation; DNA Repair; Genes, p53; Growth Substances; Humans; Methylation; Mice; Mice, Transgenic; Neoplasms; Rats | 2001 |
Genetics of neural tube defects.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Double-Blind Method; Female; Folic Acid; Humans; Infant, Newborn; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Neural Tube Defects; Oxidoreductases Acting on CH-NH Group Donors; Placebos; Pregnancy; Randomized Controlled Trials as Topic; Risk Factors; Transcription Factors; Vitamins | 2001 |
Cobalamin deficiency and the pathogenesis of nervous system disease.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Disease Models, Animal; Humans; Methylation; Methylmalonyl-CoA Mutase; Nervous System Diseases; Nitrous Oxide; Vitamin B 12; Vitamin B 12 Deficiency | 1992 |
The X chromosome in development in mouse and man.
Topics: Animals; Disease Models, Animal; Dosage Compensation, Genetic; Embryonic and Fetal Development; Female; Genetic Diseases, Inborn; Humans; Male; Methylation; Mice; Mosaicism; Sequence Homology, Nucleic Acid; X Chromosome | 1992 |
Models of hepatocarcinogenesis in the rat--contrasts and comparisons.
Topics: Animals; Animals, Newborn; Carcinogens; Diet; Disease Models, Animal; Female; Hepatectomy; Liver Neoplasms, Experimental; Methylation; Pregnancy; Rats | 1986 |
[Experimental allergic encephalomyelitis antigen (author's transl)].
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cerebrospinal Fluid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Haplorhini; Immunity, Maternally-Acquired; Methylation; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Peptides; Proteins; Rats; Species Specificity | 1974 |
1 trial(s) available for isomethyleugenol and Disease Models, Animal
Article | Year |
---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
264 other study(ies) available for isomethyleugenol and Disease Models, Animal
Article | Year |
---|---|
CircRNA MFACR Is Upregulated in Myocardial Infarction and Downregulates miR-125b to Promote Cardiomyocyte Apoptosis Induced by Hypoxia.
Topics: Animals; Apoptosis; Case-Control Studies; Cell Hypoxia; Cell Line; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Male; Methylation; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Myocardial Infarction; Myocytes, Cardiac; RNA Processing, Post-Transcriptional; RNA, Circular; Signal Transduction | 2021 |
Histone modification of pain-related gene expression in spinal cord neurons under a persistent postsurgical pain-like state by electrocautery.
Topics: Animals; Annexins; Benzazepines; Cornified Envelope Proline-Rich Proteins; Disease Models, Animal; Electrocoagulation; Female; Foot Injuries; Gene Expression Regulation; Gene Knock-In Techniques; Genes, fos; Genes, Reporter; Histone Code; Histones; Hyperalgesia; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuralgia; Neurons; Pain, Postoperative; Pyrimidines; RNA, Messenger; Spinal Cord; Tamoxifen | 2021 |
PPAR-α Hypermethylation in the Hippocampus of Mice Exposed to Social Isolation Stress Is Associated with Enhanced Neuroinflammation and Aggressive Behavior.
Topics: Aggression; Animals; Behavior, Animal; Chromatin Assembly and Disassembly; CpG Islands; Disease Models, Animal; Disease Susceptibility; Epigenesis, Genetic; Gene Expression; Hippocampus; Inflammation; Inflammation Mediators; Male; Methylation; Mice; PPAR alpha; Promoter Regions, Genetic; Signal Transduction; Social Isolation; Stress, Psychological | 2021 |
m6A regulator-mediated RNA methylation modification patterns and immune microenvironment infiltration characterization in severe asthma.
Topics: Adenosine; Animals; Asthma; Biomarkers; Cellular Microenvironment; Computational Biology; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Methylation; Mice; Models, Biological; RNA, Messenger; ROC Curve; Severity of Illness Index; Transcriptome | 2021 |
METTL3-mediated m
Topics: Adenosine; Animals; Autophagy; Autophagy-Related Protein 7; Cartilage, Articular; Cell Line; Cellular Senescence; Chondrocytes; Coculture Techniques; Disease Models, Animal; Disease Progression; Female; GATA4 Transcription Factor; Gene Expression; Humans; Immunoprecipitation; Male; Methylation; Methyltransferases; Mice; Middle Aged; Osteoarthritis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Synoviocytes; Up-Regulation | 2022 |
Alteration of the m
Topics: Adenosine; Animals; Autoimmune Diseases; Bleomycin; Connective Tissue Diseases; Disease Models, Animal; Female; Fibrosis; Gene Expression; Methylation; Mice, Inbred BALB C; RNA, Messenger; Skin | 2021 |
Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice.
Topics: Adenosine; Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Case-Control Studies; Depressive Disorder, Major; Disease Models, Animal; Down-Regulation; Female; Gene Knockdown Techniques; Healthy Volunteers; Hippocampus; Humans; Male; Methylation; Mice; Mice, Knockout; Middle Aged; Receptors, Adrenergic, beta-2; Young Adult | 2021 |
Induction of m
Topics: Animals; Disease Models, Animal; Drug Resistance, Neoplasm; Exosomes; Humans; Membrane Glycoproteins; Methylation; Mice; Mice, Knockout; Multiple Myeloma; Nerve Tissue Proteins; RNA, Long Noncoding; Signal Transduction; Tumor Microenvironment; Up-Regulation | 2022 |
3-hydroxy butyrate dehydrogenase 2 deficiency aggravates systemic lupus erythematosus progression in a mouse model by promoting CD40 ligand demethylation.
Topics: Animals; CD40 Ligand; Disease Models, Animal; Female; Hydroxybutyrate Dehydrogenase; Lupus Erythematosus, Systemic; Methylation; Mice; Mice, Inbred BALB C; Th1 Cells; Th2 Cells | 2022 |
CircMET promotes tumor proliferation by enhancing CDKN2A mRNA decay and upregulating SMAD3.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Proliferation; Chromatin Immunoprecipitation Sequencing; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Methylation; Mice; Models, Biological; Protein Binding; Proto-Oncogene Proteins c-met; RNA Processing, Post-Transcriptional; RNA Stability; RNA Transport; RNA, Circular; RNA, Messenger; Smad3 Protein; Translocation, Genetic | 2022 |
Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; China; Disease Models, Animal; Glycolysis; Histology; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Methylation; Mice; Protein-Arginine N-Methyltransferases | 2022 |
Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys.
Topics: Acute Kidney Injury; Adenosine; Animals; Cell Line; Disease Models, Animal; Extracellular Vesicles; Ischemia; Kidney; Methylation; Mice; Oxidative Stress; Rats, Sprague-Dawley; Repressor Proteins; RNA, Transfer; Transcription, Genetic | 2022 |
Kynurenic Acid and Its Analog SZR104 Exhibit Strong Antiinflammatory Effects and Alter the Intracellular Distribution and Methylation Patterns of H3 Histones in Immunochallenged Microglia-Enriched Cultures of Newborn Rat Brains.
Topics: Amides; Animals; Animals, Newborn; Anti-Inflammatory Agents; Cells, Cultured; Chemokine CXCL10; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Kynurenic Acid; Lipopolysaccharides; Male; Methylation; Microglia; Pregnancy; Rats; Receptors, CCR1 | 2022 |
Inhibition of A2AR gene methylation alleviates white matter lesions in chronic cerebral hypoperfusion rats.
Topics: Animals; Brain Ischemia; Cognitive Dysfunction; Disease Models, Animal; Maze Learning; Methylation; Rats; Rats, Sprague-Dawley; White Matter | 2022 |
METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma.
Topics: Animals; Disease Models, Animal; Glaucoma; Histones; Intraocular Pressure; Methylation; Mice; Mutation; Retinal Ganglion Cells | 2022 |
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Methylation; RNA Splicing Factors; RNA, Messenger; RNA, Small Interfering | 2023 |
Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease.
Topics: Animals; Disease Models, Animal; Humans; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polychlorinated Biphenyls; RNA, Messenger | 2023 |
Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; DNA; DNA Methylation; Humans; Methylation; Methyltransferases; Mice; Mice, Transgenic; Muscle, Skeletal; RNA; RNA Processing, Post-Transcriptional; Superoxide Dismutase; Superoxide Dismutase-1 | 2022 |
EZH2 Promotes Cholangiocarcinoma Development and Progression through Histone Methylation and microRNA-Mediated Down-Regulation of Tumor Suppressor Genes.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Genes, Tumor Suppressor; Histones; Humans; Methylation; Mice; MicroRNAs | 2022 |
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Humans; Liver Neoplasms; Methylation; Phosphoglycerate Dehydrogenase; Protein-Arginine N-Methyltransferases; Repressor Proteins; Serine | 2023 |
METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
Topics: Adenosine; Animals; Dependovirus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acid Synthase, Type I; Fatty Acids; Gene Deletion; Glucose; Hepatocytes; Homeostasis; Humans; Insulin Resistance; Liver; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Knockout; Obesity; RNA, Messenger | 2019 |
Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil.
Topics: Acetylation; Animals; Cell Death; Dendritic Spines; Dentate Gyrus; Disease Models, Animal; Donepezil; Doublecortin Protein; Epigenesis, Genetic; Ethanol; Hippocampus; Humans; Inflammation; Methylation; Neurogenesis; Rats; Underage Drinking | 2019 |
Effect of SOD2 methylation on mitochondrial DNA4834-bp deletion mutation in marginal cells under oxidative stress.
Topics: Animals; Cell Culture Techniques; Disease Models, Animal; DNA, Mitochondrial; Ear, Inner; Hydrogen Peroxide; Methylation; Oxidative Stress; Presbycusis; Rats; Rats, Wistar; Sequence Deletion; Superoxide Dismutase | 2020 |
Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Colitis; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Lipopolysaccharides; Macrophages; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 2019 |
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Topics: Animals; Bone Marrow Transplantation; Cell Lineage; Disease Models, Animal; Doxycycline; Epigenesis, Genetic; Erythroid Cells; Female; Granulocytes; Histones; Leukemia, T-Cell; Lysine; Male; Methionine; Methylation; Mice; Mice, Transgenic; Mouse Embryonic Stem Cells; Mutation; Signal Transduction; Survival Analysis; T-Lymphocytes; Teratoma | 2019 |
Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation.
Topics: Adolescent; Adult; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Bone Marrow; Bone Marrow Transplantation; Child; Disease Models, Animal; Down-Regulation; Female; Forkhead Transcription Factors; Gene Deletion; Gene Expression Profiling; Graft vs Host Disease; Humans; Male; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Protein Serine-Threonine Kinases; T-Lymphocytes, Regulatory; Transcription, Genetic | 2020 |
SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish.
Topics: Animals; Cell Differentiation; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; Histones; Methylation; Neural Stem Cells; Neural Tube; Prosencephalon; SOX Transcription Factors; Zebrafish; Zebrafish Proteins | 2019 |
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2019 |
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Topics: Animals; Cell Proliferation; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Methionine; Methylation; Mice, Inbred C57BL; Mice, Knockout; Multiple Sclerosis; Th17 Cells | 2020 |
Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway.
Topics: Aging; Animals; Disease Models, Animal; DNA-Binding Proteins; Female; Hematopoietic Stem Cells; Histones; Humans; Hypercholesterolemia; Male; Methylation; Mice; Mice, Knockout; Phenotype; Proto-Oncogene Proteins | 2020 |
Epigenetic Regulation of
Topics: Acetylation; Animals; Brain Injuries, Traumatic; Chromatin Immunoprecipitation; Disease Models, Animal; Enhancer Elements, Genetic; Epigenesis, Genetic; Histones; Methylation; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Regeneration; Wnt3A Protein | 2020 |
The effect of folic acid deficiency on Mest/Peg1 in neural tube defects.
Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Female; Fetus; Folic Acid Deficiency; Gene Expression Regulation; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Methylation; Mice; Mice, Inbred C57BL; Neural Tube Defects; Proteins; Wnt Signaling Pathway | 2021 |
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Topics: Animals; Bacterial Adhesion; Cell Line; Disease Models, Animal; Epithelial Cells; Flagella; Flagellin; Histone-Lysine N-Methyltransferase; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Methylation; Mice; NIH 3T3 Cells; Protein Processing, Post-Translational; Salmonella Infections; Salmonella typhimurium | 2020 |
Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Base Sequence; Biological Transport; CCCTC-Binding Factor; Cholesterol; Cyclin-Dependent Kinase Inhibitor p15; Disease Models, Animal; DNA; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Foam Cells; Histones; Humans; Lipid Metabolism; Methylation; Mice; Mice, Knockout; Plaque, Atherosclerotic; Primary Cell Culture; Promoter Regions, Genetic; RNA, Long Noncoding; THP-1 Cells | 2020 |
Long noncoding RNA ANRIL promotes the malignant progression of cholangiocarcinoma by epigenetically repressing ERRFI1 expression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cholangiocarcinoma; Disease Models, Animal; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins | 2020 |
Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Cell Line, Tumor; Disease Models, Animal; HEK293 Cells; Humans; Inflammation; Macrophage Activation; Macrophages; Male; MAP Kinase Signaling System; Methylation; Mice; Models, Biological; Myeloid Differentiation Factor 88; Protein Methyltransferases; ras Proteins; RAW 264.7 Cells; Substrate Specificity; Toll-Like Receptors; Transcription Factor AP-1 | 2020 |
Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2.
Topics: Animals; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Knockout Techniques; Histones; Liver; Liver Cirrhosis; Male; Methylation; Mice; Polycomb Repressive Complex 2; Sequence Analysis, RNA; Sex Characteristics | 2020 |
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation.
Topics: Abnormalities, Multiple; Aggression; Animals; Craniofacial Abnormalities; Dendritic Spines; Disease Models, Animal; Growth Disorders; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Hypertrichosis; Intellectual Disability; Male; Mental Retardation, X-Linked; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein | 2020 |
m
Topics: Adenosine; Animals; Biomarkers; Bone Marrow Failure Disorders; Cell Differentiation; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Hematopoiesis; Hematopoietic Stem Cells; Immunity, Innate; Immunophenotyping; Methylation; Methyltransferases; Mice; Mice, Knockout; RNA, Double-Stranded | 2020 |
MicroRNA-200a Inhibits Inflammation and Atherosclerotic Lesion Formation by Disrupting EZH2-Mediated Methylation of STAT3.
Topics: Animals; Apoptosis; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipoproteins, LDL; Lysine; Male; Methylation; Mice, Knockout, ApoE; MicroRNAs; Phosphorylation; Plaque, Atherosclerotic; Signal Transduction; STAT3 Transcription Factor | 2020 |
Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin.
Topics: Animals; Arginine; beta Catenin; Cells, Cultured; Disease Models, Animal; Epigenesis, Genetic; Histones; Hypertrophy, Left Ventricular; Male; Methylation; Mice, Inbred C57BL; Myocytes, Cardiac; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Cell Survival; Cholesterol; Cornus; Disease Models, Animal; Foam Cells; Glucans; Immunohistochemistry; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Methylation; Mice; Mice, Knockout; Molecular Weight; Monosaccharides; Plant Extracts; Plaque, Atherosclerotic; RAW 264.7 Cells; Spectrum Analysis; Structure-Activity Relationship | 2020 |
β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer.
Topics: Adenosine; Animals; Apoptosis; beta Catenin; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; Humans; Methylation; Mice; MicroRNAs; Models, Biological; Protein Biosynthesis; RNA Interference; RNA, Messenger; Xenograft Model Antitumor Assays | 2020 |
Upregulation of METTL14 mediates the elevation of PERP mRNA N
Topics: Adenine; Animals; Binding Sites; Biomarkers, Tumor; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Heterografts; Humans; Kaplan-Meier Estimate; Membrane Proteins; Methylation; Methyltransferases; Mice; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Protein Binding; RNA Stability; RNA, Messenger | 2020 |
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N
Topics: Adenosine; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3 beta; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NFATC Transcription Factors; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; RNA Stability; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing.
Topics: Alternative Splicing; Animals; Brain; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Humans; Methyl-CpG-Binding Protein 2; Methylation; Mice; Mice, Knockout; Mutation; Neurons; Protein Binding; Rett Syndrome; Transcriptome | 2020 |
DM-induced Hypermethylation of IR and IGF1R attenuates mast cell activation and airway responsiveness in rats.
Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Susceptibility; Gene Expression; Gene Knockdown Techniques; Histamine; Immunoglobulin E; Inflammation Mediators; Insulin; Mast Cells; Methylation; Rats; Receptor, IGF Type 1; Receptor, Insulin | 2020 |
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Lysine; Methylation; Mice, Knockout; Proto-Oncogene Proteins c-myc; ras Proteins; Tumor Suppressor Protein p53 | 2020 |
The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice.
Topics: Acetylation; Animals; Brain; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Dwarfism, Pituitary; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Growth Hormone; Histone Code; Histones; Homeodomain Proteins; Hormone Replacement Therapy; Intra-Abdominal Fat; Liver; Longevity; Methylation; Mice; Subcutaneous Fat | 2020 |
A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice.
Topics: 3-Hydroxybutyric Acid; Acetylation; Animals; Ataxia; Brain; Brain Injuries, Traumatic; Diet, Ketogenic; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Disease Models, Animal; Docosahexaenoic Acids; Epigenesis, Genetic; Glycemic Index; Histone Code; Inflammation; Lameness, Animal; Leucine; Male; Methylation; Mice; Morris Water Maze Test; Oligodendroglia; Paresis; Postural Balance; Rotarod Performance Test; Sensation Disorders; Signal Transduction; Spatial Memory; TOR Serine-Threonine Kinases; Triglycerides | 2021 |
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Humans; Methylation; Methyltransferases; Mice; Neurodegenerative Diseases; RNA Stability | 2021 |
BCL-6 promotes the methylation of miR-34a by recruiting EZH2 and upregulating CTRP9 to protect ischemic myocardial injury.
Topics: Adiponectin; Animals; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Glycoproteins; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Proto-Oncogene Proteins c-bcl-6; Signal Transduction; Up-Regulation | 2021 |
Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific
Topics: Adenosine; Animals; Celiac Disease; Cell Line; Disease Models, Animal; Epithelial Cells; Exportin 1 Protein; HLA-DQ Antigens; Humans; Intestinal Mucosa; Karyopherins; Methylation; Mice, Knockout; NF-kappa B; Polymorphism, Single Nucleotide; Receptors, Cytoplasmic and Nuclear; RNA | 2022 |
The UFSP2/UFMylation Pathway Is Involved in Silica-Induced Pulmonary Injury.
Topics: Animals; China; Cysteine Endopeptidases; Disease Models, Animal; Epithelial-Mesenchymal Transition; Lung; Lung Injury; Male; Methylation; Mice; Mice, Inbred C57BL; Proteins; Pulmonary Fibrosis; Silicon Dioxide; Silicosis | 2021 |
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Topics: Amino Acid Sequence; Animals; Arginine; Axonal Transport; Brain-Derived Neurotrophic Factor; Cell Death; Disease Models, Animal; Drosophila melanogaster; Epigenesis, Genetic; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neuromuscular Junction; Neurons; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Transport Vesicles | 2021 |
The role of RNA m
Topics: Adenine; Animals; Animals, Newborn; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Male; Methylation; Methyltransferases; Pulmonary Artery; Rats, Sprague-Dawley; RNA; RNA Processing, Post-Transcriptional; Time Factors; Vascular Remodeling; Ventricular Function, Right; Ventricular Pressure | 2021 |
Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dogs; Humans; Lymphoma, Non-Hodgkin; Methylation; Protein-Arginine N-Methyltransferases | 2021 |
Calcitonin gene-related peptide regulates spinal microglial activation through the histone H3 lysine 27 trimethylation via enhancer of zeste homolog-2 in rats with neuropathic pain.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Gene Expression; Histones; Indoles; Inflammation; Male; Methylation; Microglia; Neuralgia; Nociceptors; Peptide Fragments; Peripheral Nerve Injuries; Pyridones; Rats; Rats, Wistar; Signal Transduction; Spinal Cord | 2021 |
DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.
Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; Methylation; Mice; PPAR alpha; Promoter Regions, Genetic; Retina | 2021 |
Interaction of tau with HNRNPA2B1 and N
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Case-Control Studies; Cerebral Cortex; Disease Models, Animal; Disease Progression; Female; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Aggregates; Protein Aggregation, Pathological; RNA; RNA Processing, Post-Transcriptional; Severity of Illness Index; tau Proteins | 2021 |
Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence.
Topics: Acetylation; Alcohol Abstinence; Alcohol Withdrawal Seizures; Alcoholism; Animals; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Ethanol; Gene Expression Regulation, Enzymologic; Gene Regulatory Networks; Histone-Lysine N-Methyltransferase; Histones; Inhalation Exposure; Intracellular Signaling Peptides and Proteins; Male; Methylation; Mice; Prefrontal Cortex; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Time Factors; Ubiquitination | 2017 |
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).
Topics: Administration, Oral; Amino Acid Oxidoreductases; Animals; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Halogenation; Humans; Lung; Lung Diseases; Male; Methylation; Mice, Inbred C57BL; Models, Molecular; Pyridines; Structure-Activity Relationship | 2017 |
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Checkpoint Kinase 1; Dealkylation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Methylation; Mice; Molecular Structure; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Xenograft Model Antitumor Assays | 2017 |
Changes in the content of fatty acids in CA1 and CA3 areas of the hippocampus of Krushinsky-Molodkina rats after single and fivefold audiogenic seizures.
Topics: Acoustic Stimulation; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromatography, Gas; Disease Models, Animal; Fatty Acids; Male; Methylation; Rats; Seizures | 2017 |
m
Topics: Adenosine; Adoptive Transfer; Animals; Cell Differentiation; Cell Proliferation; Colitis; Disease Models, Animal; DNA-Binding Proteins; Female; Homeostasis; Interleukin-7; Male; Methylation; Methyltransferases; Mice; RNA Stability; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes | 2017 |
Involvement of Cryptosporidium parvum Cdg7_FLc_1000 RNA in the Attenuation of Intestinal Epithelial Cell Migration via Trans-Suppression of Host Cell SMPD3.
Topics: Animals; Cell Line; Cell Movement; Cryptosporidiosis; Cryptosporidium parvum; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Epithelial Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Intestinal Diseases; Methylation; Mice; Protein Processing, Post-Translational; RNA, Protozoan; Sphingomyelin Phosphodiesterase | 2017 |
Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of
Topics: Animals; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Liver Neoplasms; Methylation; Mice; Mice, Nude; Protein Binding; Proteins; Proto-Oncogene Proteins; RNA-Binding Proteins; Transcription Factors | 2018 |
Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Coffee; Cognition; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Electrophysiology; Fear; Female; Long-Term Potentiation; Male; Maze Learning; Methylation; Mice; Mice, Inbred C57BL; Nervous System Diseases; Neuronal Plasticity; Phosphorylation; Serotonin; Solubility | 2017 |
EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis.
Topics: 3' Untranslated Regions; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Female; Galectins; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Interferon-gamma; Liver Neoplasms; Methylation; Mice; MicroRNAs; Promoter Regions, Genetic; RNA Interference | 2018 |
Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers.
Topics: Animals; Antigens, Neoplasm; Casein Kinase II; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Methylation; Mice; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; SKP Cullin F-Box Protein Ligases; Stomach Neoplasms; Ubiquitination | 2018 |
Biochemical validation of EHMT1 missense mutations in Kleefstra syndrome.
Topics: Amino Acid Substitution; Animals; Chromosome Deletion; Chromosomes, Human, Pair 9; Craniofacial Abnormalities; Disease Models, Animal; Embryonic Stem Cells; Female; Heart Defects, Congenital; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Intellectual Disability; Methylation; Mice; Mice, Knockout; Models, Molecular; Mutation, Missense; Protein Binding; Protein Conformation; Protein Multimerization; Structure-Activity Relationship | 2018 |
DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.
Topics: Adenosine; Amino Acid Motifs; Animals; Calpain; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Male; Methylation; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Retina; Retinal Degeneration | 2018 |
Erythropoietin Upregulates Brain Hemoglobin Expression and Supports Neuronal Mitochondrial Activity.
Topics: Animals; Aspartic Acid; Brain; Cell Respiration; Cuprizone; Disease Models, Animal; Electron Transport Complex III; Erythropoietin; Hemoglobins; Histones; Lysine; Male; Methylation; Mice, Inbred C57BL; Mitochondria; Models, Biological; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Neurons; Up-Regulation | 2018 |
Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.
Topics: Animals; Animals, Newborn; Cadherins; Chromosome Deletion; Chromosomes, Human, Pair 9; Cognitive Dysfunction; Craniofacial Abnormalities; Disease Models, Animal; Gene Expression Regulation; Heart Defects, Congenital; Hippocampus; Histone-Lysine N-Methyltransferase; Histones; Intellectual Disability; Lysine; Male; Methylation; Mice, Knockout | 2018 |
CTLA-4 methylation regulates the pathogenesis of myasthenia gravis and the expression of related cytokines.
Topics: Acetylcholinesterase; Adolescent; Adult; Aged; Animals; Child; CTLA-4 Antigen; Cytokines; Disease Models, Animal; Female; Humans; Male; Methylation; Middle Aged; Myasthenia Gravis; Rats, Inbred Lew; T-Lymphocytes, Regulatory; Up-Regulation; Young Adult | 2018 |
Enhancer of zeste homolog 2-catalysed H3K27 trimethylation plays a key role in acute-on-chronic liver failure via TNF-mediated pathway.
Topics: Acute-On-Chronic Liver Failure; Animals; Biocatalysis; Chromatin; Cytokines; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Indoles; Inflammation Mediators; Kupffer Cells; Lipopolysaccharides; Liver; Lysine; Methylation; Mice, Inbred C57BL; NF-kappa B; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyridones; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Study on the Structure of Ginseng Glycopeptides with Anti-Inflammatory and Analgesic Activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytokines; Disease Models, Animal; Glycopeptides; Inflammation Mediators; Male; Methylation; Molecular Structure; Pain; Pain Management; Panax; Rats; Structure-Activity Relationship; Tandem Mass Spectrometry | 2018 |
X chromosome protects against bladder cancer in females via a
Topics: Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, X-Linked; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Histone Demethylases; Methylation; Mice; Mice, Knockout; Mutation; Prognosis; Sex Chromosomes; Sex Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; X Chromosome | 2018 |
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.
Topics: Aging; Animals; Archaeal Proteins; Chlorocebus aethiops; Coronavirus; Coronavirus Infections; Disease Models, Animal; Immunocompromised Host; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mutation; Severe acute respiratory syndrome-related coronavirus; Vaccines, Attenuated; Vero Cells; Viral Nonstructural Proteins; Viral Vaccines; Virus Replication | 2018 |
Inhibition of H3K27me3 demethylases attenuates asthma by reversing the shift in airway smooth muscle phenotype.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Histone Demethylases; Humans; Methylation; Mice; Mitogen-Activated Protein Kinases; Muscle, Smooth; Myocytes, Smooth Muscle; Phenotype; Proto-Oncogene Proteins c-akt; Signal Transduction | 2018 |
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epigenesis, Genetic; Gene Expression; Gene Knockdown Techniques; Glutarates; Histones; Humans; Kidney Neoplasms; Methylation; Molecular Targeted Therapy; Phenotype; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2018 |
Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Gene Expression Profiling; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice, Transgenic; Myeloid Cells; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Proto-Oncogene Proteins | 2018 |
Arginine methylation of FOXP3 is crucial for the suppressive function of regulatory T cells.
Topics: Animals; Arginine; Biomarkers; Cell Line; Cytokines; Disease Models, Animal; Fluorescent Antibody Technique; Forkhead Transcription Factors; Gene Expression Profiling; Graft vs Host Disease; Humans; Kaplan-Meier Estimate; Male; Methylation; Mice; Mutation; Protein Processing, Post-Translational; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2019 |
Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.
Topics: Adenosine; Animals; Benzamides; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histone Code; Histones; Humans; Indoles; Methylation; Mice; Morpholines; Pyridones; T-Lymphocytes | 2018 |
Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.
Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Male; Methylation; Neurons; Parvalbumins; Prefrontal Cortex; Rats; Rats, Wistar; Schizophrenia; Social Isolation | 2019 |
Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Epigenesis, Genetic; Glucose Transporter Type 4; Histones; Humans; Insulin; Lysine; Male; Methylation; Mice; Muscle, Skeletal; Promoter Regions, Genetic; Rats; Resveratrol | 2019 |
m
Topics: Adenosine; Animals; Cell Line, Tumor; Cytomegalovirus; Disease Models, Animal; Female; Fibroblasts; Herpesviridae Infections; Host-Pathogen Interactions; Humans; Immunity, Innate; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interferon Type I; Male; Methylation; Methyltransferases; Mice; Mice, Inbred ICR; Mice, Knockout; Muromegalovirus; RNA-Binding Proteins; RNA, Messenger | 2019 |
Structure characterization of low molecular weight sulfate Ulva polysaccharide and the effect of its derivative on iron deficiency anemia.
Topics: Anemia, Iron-Deficiency; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Hemoglobins; Iron; Male; Methylation; Molecular Weight; Monosaccharides; Particle Size; Polysaccharides; Rats, Wistar; Reference Standards; Spectroscopy, Fourier Transform Infrared; Sulfates; Transferrin; Ulva; Weight Gain | 2019 |
Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila.
Topics: Animals; Animals, Genetically Modified; Cardiomyopathies; Diet, High-Fat; Disease Models, Animal; Drosophila; Drosophila Proteins; Female; Genetic Predisposition to Disease; Histones; Humans; Lipase; Lipid Metabolism; Male; Methylation; Myocardium; Obesity; Positive Transcriptional Elongation Factor B; Triglycerides | 2019 |
Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats.
Topics: Adenosine; AIDS Dementia Complex; Animals; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation; Hippocampus; HIV-1; Host-Pathogen Interactions; Humans; Male; Methylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; RNA Splicing; RNA, Messenger; RNA, Viral; Sequence Analysis, RNA; Transcriptome | 2019 |
Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice.
Topics: Animals; Autistic Disorder; Disease Models, Animal; Female; Haploinsufficiency; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Mice; Microfilament Proteins; Nerve Tissue Proteins; Prefrontal Cortex; Quinazolines | 2020 |
Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Chromosome Deletion; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hippocampus; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Memory Disorders; Methylation; Mice; Mice, Transgenic; Prefrontal Cortex; Synapses | 2019 |
Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy.
Topics: Animals; Blood-Brain Barrier; Brain Diseases; Brain Edema; Caveolin 1; Cytokines; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Interferon Type I; Lipopolysaccharides; Methylation; Mice; Orthomyxoviridae; Orthomyxoviridae Infections | 2019 |
Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.
Topics: Animals; Bleomycin; Cell Movement; Disease Models, Animal; Endothelial Cells; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Mice; Microfilament Proteins; Neovascularization, Physiologic; Receptors, Notch; Scleroderma, Diffuse; Signal Transduction | 2019 |
Allyl isothiocyanate regulates lysine acetylation and methylation marks in an experimental model of malignant melanoma.
Topics: Acetylation; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Humans; Isothiocyanates; Lysine; Melanoma; Methylation; Mice | 2020 |
An augmentation in histone dimethylation at lysine nine residues elicits vision impairment following traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Histones; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Myelin Sheath; NF-E2-Related Factor 2; Optic Nerve; Oxidative Stress; Retinal Ganglion Cells; Vision Disorders | 2019 |
Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.
Topics: Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Female; Folic Acid; Growth and Development; Homocysteine; Methylation; MicroRNAs; Nervous System; Pregnancy; Rats, Wistar; Vitamin B 12 | 2019 |
Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death.
Topics: Adenosine; Animals; Apoptosis; Brain; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Epigenesis, Genetic; Male; Methylation; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympatholytics | 2019 |
Respiratory syncytial virus promoted the differentiation of Th17 cells in airway microenvironment through activation of Notch-1/Delta3.
Topics: AIRE Protein; Animals; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cellular Microenvironment; Disease Models, Animal; Intracellular Signaling Peptides and Proteins; Jagged-1 Protein; Lung; Male; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Receptor, Notch1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Th1 Cells; Th17 Cells; Transcription Factors | 2019 |
Epigenetic regulation of phosphodiesterase 4d in restrictive cardiomyopathy mice with cTnI mutations.
Topics: Acetylation; Animals; Cardiomyopathy, Restrictive; Cell Nucleus; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; DNA-Binding Proteins; Epigenesis, Genetic; Heart; Histone Deacetylase 1; Histones; Lysine; Methylation; Mice; Muscle Proteins; Mutation; Myocytes, Cardiac; Promoter Regions, Genetic; Transcription Factors; Troponin I | 2020 |
Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.
Topics: Animals; Autoimmunity; Cell Line; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Gene Regulatory Networks; Male; Methylation; Mice; Mice, Knockout; Models, Molecular; Multiple Sclerosis; Neurons; Signal Transduction; Structure-Activity Relationship; Synapses; T-Lymphocyte Subsets; tau Proteins; Transcription, Genetic | 2019 |
Neuroprotective effects of lithium on a chronic MPTP mouse model of Parkinson's disease via regulation of α‑synuclein methylation.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Introns; Lithium; Male; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; MPTP Poisoning; Neuroprotective Agents; Substantia Nigra | 2019 |
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
Topics: Adipocytes; Adipokines; Animals; Bone Diseases; Bone Marrow; Bone Resorption; Cell Line, Tumor; Cellular Reprogramming; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Methylation; Mice; Multiple Myeloma; Osteoblasts; Osteogenesis; Polycomb Repressive Complex 2; PPAR gamma; Promoter Regions, Genetic; Remission Induction; Signal Transduction; Sp1 Transcription Factor; Up-Regulation | 2019 |
Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells.
Topics: Adult; Animals; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Senescence; Disease Models, Animal; Female; Gallbladder Neoplasms; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; Middle Aged; Models, Biological; Prognosis; RNA Interference; RNA, Long Noncoding; Young Adult | 2019 |
Control of Hematopoietic Stem and Progenitor Cell Function through Epigenetic Regulation of Energy Metabolism and Genome Integrity.
Topics: Anemia; Animals; Disease Models, Animal; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation; Genome; Hematopoiesis; Hematopoietic Stem Cells; Histones; Humans; Methylation; Mice; Mice, Knockout; Models, Molecular; Oxygen Consumption; Phenotype; Pyruvate Kinase; Resting Phase, Cell Cycle; Transcription Factors | 2019 |
Position-dependent correlation between TBX22 exon 5 methylation and palatal shelf fusion in the development of cleft palate.
Topics: Animals; Cleft Palate; Disease Models, Animal; Embryonic Development; Exons; Female; Genetic Diseases, X-Linked; Methylation; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy; T-Box Domain Proteins | 2019 |
Profiling histone modifications in the normal mouse kidney and after unilateral ureteric obstruction.
Topics: Acetylation; Animals; Biomarkers; Disease Models, Animal; Gene Expression Regulation; Histones; Kidney; Kidney Diseases; Male; Mass Spectrometry; Methylation; Mice, Inbred C57BL; Protein Processing, Post-Translational; Proteomics; Transcription, Genetic; Ureteral Obstruction | 2019 |
Epitranscriptomic mechanisms of N6-methyladenosine methylation regulating mammalian hypertension development by determined spontaneously hypertensive rats pericytes.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adenosine; Animals; Disease Models, Animal; Epigenomics; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; High-Throughput Nucleotide Sequencing; Hypertension; Male; Methylation; Organ Specificity; Pericytes; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2019 |
Premature impairment of methylation pathway and cardiac metabolic dysfunction in fa/fa obese Zucker rats.
Topics: Adipose Tissue, White; Age Factors; Animals; Betaine; Disease Models, Animal; Inositol; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylation; Myocardium; Obesity; Phosphorylcholine; Rats; Rats, Zucker | 2013 |
Rational design of a flavivirus vaccine by abolishing viral RNA 2'-O methylation.
Topics: Animals; Antibodies, Viral; Disease Models, Animal; Encephalitis Virus, Japanese; Encephalitis, Japanese; Female; Japanese Encephalitis Vaccines; Leukocytes, Mononuclear; Methylation; Mice; Mice, Inbred BALB C; RNA, Viral; Survival Analysis; tRNA Methyltransferases; Vaccines, Attenuated | 2013 |
Critical role of transmethylation in TLR signaling and systemic lupus erythematosus.
Topics: Adenine; Animals; Antigen-Presenting Cells; Autoantibodies; B-Lymphocytes; Butyrates; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Female; Immunoglobulin G; Immunosuppressive Agents; Kidney; Lupus Erythematosus, Systemic; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Protein Processing, Post-Translational; Signal Transduction; Toll-Like Receptors | 2013 |
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cytosol; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Inclusion Bodies; Membrane Proteins; Methylation; Methyltransferases; Mutant Proteins; Mutation; Protein Binding; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; Subcellular Fractions | 2013 |
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.
Topics: Acetylation; Animals; Apoptosis; Bleomycin; Cells, Cultured; Disease Models, Animal; fas Receptor; Fibroblasts; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Pulmonary Fibrosis | 2013 |
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Topics: Animals; Cell Nucleus; Cellular Senescence; Disease Models, Animal; Fibroblasts; Gene Knockout Techniques; Hand Strength; Humans; Lamin Type A; Membrane Proteins; Metalloendopeptidases; Methylation; Mice; Mice, Mutant Strains; Nuclear Proteins; Progeria; Protein Methyltransferases; Protein Precursors; TOR Serine-Threonine Kinases; Weight Gain | 2013 |
Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
Topics: Animals; Disease Models, Animal; DNA Damage; DNA Repair; Enzyme Stability; Fibroblasts; HEK293 Cells; Heterochromatin; Histones; Humans; Lamin Type A; Longevity; Lysine; Methylation; Methyltransferases; Mice; Nuclear Proteins; Progeria; Protein Binding; Protein Precursors; Protein Processing, Post-Translational; Repressor Proteins | 2013 |
Promoted interaction of nuclear factor-κB with demethylated cystathionine-β-synthetase gene contributes to gastric hypersensitivity in diabetic rats.
Topics: Amino Acids; Analysis of Variance; Animals; Area Under Curve; Case-Control Studies; Chromatin Immunoprecipitation; CpG Islands; Cystathionine beta-Synthase; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Dose-Response Relationship, Drug; Electromyography; Enzyme Inhibitors; Female; Ganglia, Spinal; Hypersensitivity; Membrane Potentials; Methylation; Neoplasm Proteins; NF-kappa B; Nucleocytoplasmic Transport Proteins; Oxamic Acid; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Stomach Diseases; Sulfites; Up-Regulation | 2013 |
Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia.
Topics: Animals; Arginine; Diet; Disease Models, Animal; Female; Histones; Hyperhomocysteinemia; Methylation; Proteins; Rats; Rats, Wistar | 2013 |
Enhanced trimethylation of histone h3 mediates impaired expression of hepatic glucose 6-phosphatase expression in offspring from rat dams exposed to hypoxia during pregnancy.
Topics: Animals; Blood Glucose; Cell Line, Tumor; Disease Models, Animal; Female; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; Gestational Age; Glucose-6-Phosphatase; Histones; Hypoxia; Intracellular Signaling Peptides and Proteins; Liver; Male; Methylation; Oxygen; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 2014 |
Suppression of antifolate resistance by targeting the myosin Va trafficking pathway in melanoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Female; Gene Silencing; Humans; Melanoma; Methotrexate; Methylation; Mice; Myosin Heavy Chains; Myosin Type V; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2C; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays | 2013 |
Modulation of allogeneic CD8+ T-cell response by DZNep controls GVHD while preserving hematopoietic chimerism.
Topics: Adenosine; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Fas Ligand Protein; Female; Graft vs Host Disease; Granzymes; Hematopoietic Stem Cell Transplantation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Male; Methylation; Mice; Mice, Inbred C3H; T-Lymphocytes, Cytotoxic; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transplantation Chimera; Transplantation Tolerance; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2013 |
Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings.
Topics: Acids, Acyclic; Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Isoleucine; Large Neutral Amino Acid-Transporter 1; Methylation; Mice; Mice, Transgenic; Molecular Targeted Therapy; Organ Specificity; Phenylalanine; Phenylketonurias; Protein Conformation; Protein Folding; Valine | 2013 |
Amino acids as biomarkers in the SOD1(G93A) mouse model of ALS.
Topics: Age Factors; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Humans; Longevity; Male; Metabolome; Methionine Sulfoximine; Methylation; Mice; Mice, Transgenic; Mutation; Sex Factors; Superoxide Dismutase; Superoxide Dismutase-1 | 2014 |
Protective effect of demethylation treatment on cigarette smoke extract-induced mouse emphysema model.
Topics: Animals; Apoptosis; Azacitidine; Decitabine; Disease Models, Animal; DNA-Binding Proteins; Electron Transport Complex IV; Emphysema; Lung; Male; Methylation; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Proteins; RNA, Messenger; Smoking; Transcription Factors | 2013 |
Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations.
Topics: Animals; Cell Line; Disease Models, Animal; Histones; Homeodomain Proteins; Humans; Lectins, C-Type; Methylation; Mice; Mice, Inbred C57BL; MicroRNAs; Mutant Proteins; Mutation; Myelodysplastic Syndromes; Myelopoiesis; Peptide Fragments; Receptors, Cell Surface; Repressor Proteins | 2013 |
Epigenetic mechanisms of Rubinstein-Taybi syndrome.
Topics: Acetylation; Animals; Chromatin; CREB-Binding Protein; Disease Models, Animal; Epigenesis, Genetic; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; MicroRNAs; Models, Biological; Mutation; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Rubinstein-Taybi Syndrome; Sequence Deletion; Tumor Suppressor Protein p53 | 2014 |
Pulmonary vasodilation by acetazolamide during hypoxia: impact of methyl-group substitutions and administration route in conscious, spontaneously breathing dogs.
Topics: Acetazolamide; Administration, Inhalation; Administration, Oral; Animals; Arterial Pressure; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Dogs; Female; Hypoxia; Infusions, Intravenous; Methylation; Pulmonary Artery; Respiration; Structure-Activity Relationship; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents | 2014 |
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency.
Topics: Animals; Arginine; Brain; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Histones; Homocysteine; Homocystinuria; Liver; Methylation; Mice; S-Adenosylhomocysteine | 2014 |
Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation.
Topics: Animals; Cell Differentiation; Chromatin; Colitis; Disease Models, Animal; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Methylation; Mice; Mice, Knockout; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta1 | 2014 |
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins | 2014 |
Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures.
Topics: Action Potentials; Animals; Arginine; Brain; Cell Line; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Kainic Acid; Kidney; Male; Mass Spectrometry; Methylation; NAV1.2 Voltage-Gated Sodium Channel; Phosphorylation; Proteomics; Rats | 2014 |
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.
Topics: Animals; B-Lymphocytes; Blotting, Western; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Profiling; Histones; Humans; Kaplan-Meier Estimate; Lymphoma; Lymphoma, B-Cell; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Polycomb Repressive Complex 2; Proto-Oncogene Proteins c-myc; Spleen | 2014 |
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Betaine; Cells, Cultured; Cytoprotection; Disease Models, Animal; Hep G2 Cells; Humans; Lipolysis; Liver Diseases, Alcoholic; Male; Methylation; Mice; Mice, Inbred C57BL | 2014 |
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Pancreatic Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins A-raf; Signal Transduction | 2014 |
Histone modifications of the Crhr1 gene in a rat model of depression following chronic stress.
Topics: Animals; Blotting, Western; Chronic Disease; Depression; Disease Models, Animal; Histones; Hypothalamus; Male; Methylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Stress, Psychological | 2014 |
Effects of acute and sub-chronic L-dopa therapy on striatal L-dopa methylation and dopamine oxidation in an MPTP mouse model of Parkinsons disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Catechol O-Methyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Levodopa; Male; Methylation; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Parkinsonian Disorders; Time Factors | 2014 |
Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury.
Topics: Acetylation; Acute Lung Injury; Animals; Azacitidine; Blotting, Western; Capillary Permeability; Cell Proliferation; Cell Survival; Chromatin Immunoprecipitation; Decitabine; Disease Models, Animal; Drug Therapy, Combination; Endothelial Cells; Endotoxemia; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Hydroxamic Acids; In Situ Nick-End Labeling; Inflammation; Lung; Male; Methylation; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction | 2014 |
Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Coffee; Disease Models, Animal; Female; Methylation; Neuroprotective Agents; Protein Phosphatase 2; Rats; Rats, Transgenic; Serotonin | 2014 |
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: structure-activity relationship considerations.
Topics: Animals; Bone Density Conservation Agents; Carboxylic Acids; Cell Line; Cell Proliferation; Denervation; Disease Models, Animal; Female; Humans; Injections, Intraperitoneal; Interleukin-6; Methylation; Mice, Inbred C57BL; Molecular Structure; Naphthoquinones; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Random Allocation; Sciatic Nerve; Structure-Activity Relationship; Vitamin K | 2014 |
Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain.
Topics: Animals; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Methylation; Mice; Morphine; Neuralgia; Neuroblastoma; Pain Measurement; Pain Threshold; Promoter Regions, Genetic; Receptors, Opioid, mu; Sensory Receptor Cells; Spinal Cord | 2014 |
Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis.
Topics: Aminoglycosides; Animals; Apoptosis; Benzamidines; Caspase 3; Cyclopropanes; Cytoprotection; Disease Models, Animal; Hair Cells, Auditory; Histone Demethylases; Histones; Lysine; Methylation; Mice, Inbred C57BL; Neomycin; Organ of Corti; Phenyl Ethers; Piperazines | 2015 |
Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells.
Topics: Animals; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Heterografts; Histones; Humans; Kidney Neoplasms; Methylation; Mice; RNA, Long Noncoding; RNA, Small Interfering; Tumor Burden | 2014 |
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.
Topics: Amino Acid Substitution; Animals; Chromatin; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Silencing; Glioma; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methionine; Methylation; Mutation; Signal Transduction | 2014 |
Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet.
Topics: Animals; Anxiety; Azacitidine; Brain; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Decitabine; Diet, Fat-Restricted; Disease Models, Animal; Enzyme Inhibitors; Fatty Acids, Omega-3; Female; Male; Maze Learning; Methylation; Mice; Neuroblastoma; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcription Factors | 2015 |
Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Endometrial Neoplasms; Female; Histone Demethylases; Histones; Humans; Methylation; Mice; Neoplasm Grading; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.
Topics: Alternative Splicing; Animals; Base Pair Mismatch; Disease Models, Animal; HeLa Cells; Humans; Methylation; Myotonic Dystrophy; Nucleic Acid Conformation; Pseudouridine; Repetitive Sequences, Nucleic Acid; RNA; RNA-Binding Proteins; Water; Zebrafish | 2014 |
Increased plasma S-adenosylhomocysteine-accelerated atherosclerosis is associated with epigenetic regulation of endoplasmic reticulum stress in apoE-/- mice.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; S-Adenosylhomocysteine; Time Factors; Up-Regulation | 2015 |
Characterization of albendazole-randomly methylated-β-cyclodextrin inclusion complex and in vivo evaluation of its antihelmitic activity in a murine model of Trichinellosis.
Topics: Albendazole; Animals; Antiparasitic Agents; beta-Cyclodextrins; Calorimetry, Differential Scanning; Disease Models, Animal; Macromolecular Substances; Mass Spectrometry; Methylation; Mice; Muscle, Skeletal; Solubility; Trichinellosis; X-Ray Diffraction | 2014 |
EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Histones; Humans; Kinetics; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methylation; Mice; Mice, Nude; Mutation; Peptides; Polycomb Repressive Complex 2; Small Molecule Libraries; Transplantation, Heterologous | 2014 |
Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus.
Topics: Age Factors; Animals; Binding Sites; Brain-Derived Neurotrophic Factor; Choline; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gestational Age; Hippocampus; Histone Deacetylase 1; Histones; Iron; Iron Deficiencies; Iron Metabolism Disorders; Methylation; Pregnancy; Prenatal Exposure Delayed Effects; Promoter Regions, Genetic; Rats, Sprague-Dawley; RNA Polymerase II; Time Factors; Upstream Stimulatory Factors | 2015 |
Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.
Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Case-Control Studies; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Lymphatic Metastasis; Male; Methylation; Middle Aged; Neoplasm Grading; Neoplasm Staging; Tumor Burden; Urinary Bladder Neoplasms | 2015 |
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.
Topics: Actins; Animals; Cell Adhesion; Cell Movement; Cell Nucleus; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enhancer of Zeste Homolog 2 Protein; Humans; Lymphocyte Activation; Methylation; Mice; Mice, Knockout; Multiple Sclerosis; Neutrophils; Polycomb Repressive Complex 2; Protein Binding; Proto-Oncogene Proteins c-vav; Talin; Transendothelial and Transepithelial Migration | 2015 |
Demethylation of IGFBP5 by Histone Demethylase KDM6B Promotes Mesenchymal Stem Cell-Mediated Periodontal Tissue Regeneration by Enhancing Osteogenic Differentiation and Anti-Inflammation Potentials.
Topics: Animals; Cell Differentiation; Disease Models, Animal; Histones; Humans; Insulin-Like Growth Factor Binding Protein 5; Jumonji Domain-Containing Histone Demethylases; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methylation; Osteogenesis; Periodontitis; Periodontium; Regeneration; Swine; Swine, Miniature | 2015 |
RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Hematopoietic Stem Cells; Histone Demethylases; Histones; Humans; Hydroxyurea; Methylation; Mice; Mice, Transgenic; Papio; Protein Processing, Post-Translational; Reticulocytes; Transgenes; Tranylcypromine; Tretinoin; U937 Cells | 2015 |
Long-term metabolic alterations in a febrile seizure model.
Topics: Animals; Blood Glucose; Body Weight; Disease Models, Animal; Histones; Lipid Metabolism; Liver; Male; Methylation; Rats; Rats, Inbred Strains; Seizures, Febrile; Time | 2016 |
Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats.
Topics: Action Potentials; Animals; Antineoplastic Agents; Bone Neoplasms; Case-Control Studies; Disease Models, Animal; Enzyme Inhibitors; Female; Ganglia, Spinal; Hyperalgesia; Methylation; Neurons; NF-kappa B; Nitriles; Pain; Pain Management; Pain Threshold; Proline; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Sulfones; Thiocarbamates | 2015 |
Schizophrenia-Like Phenotype Inherited by the F2 Generation of a Gestational Disruption Model of Schizophrenia.
Topics: Animals; Disease Models, Animal; DNA Methylation; Dopaminergic Neurons; Female; Hippocampus; Male; Methylation; Methylazoxymethanol Acetate; Parvalbumins; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Transcription Factors; Ventral Tegmental Area | 2016 |
H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.
Topics: Animals; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; DNA Methylation; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Fluorouracil; Gene Expression Profiling; Gene Silencing; Genome-Wide Association Study; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Indoles; Inhibitory Concentration 50; Liver; Methylation; Methyltransferases; Mice; Promoter Regions, Genetic; Repressor Proteins; Tumor Escape; Xenograft Model Antitumor Assays | 2015 |
Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
Topics: Animals; Autophagy; Cell Culture Techniques; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Methionine; Methylation; Mice; Protein Phosphatase 2; S-Adenosylmethionine | 2016 |
GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Ovarian Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Gene Knock-In Techniques; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methylation; Mice; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Protein Methyltransferases; Protein Processing, Post-Translational; Protein Stability; Retinal Neovascularization; Retinopathy of Prematurity; Reverse Transcriptase Polymerase Chain Reaction | 2016 |
A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation.
Topics: Aggression; Animals; Brain; CpG Islands; Dendritic Spines; Disease Models, Animal; Gene Expression Regulation; Genes, X-Linked; Histone Demethylases; Histones; Intellectual Disability; Lysine; Memory; Methylation; Mice, Knockout; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Social Behavior; Transcription, Genetic | 2016 |
Methylthioadenosine (MTA) Regulates Liver Cells Proteome and Methylproteome: Implications in Liver Biology and Disease.
Topics: Animals; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Deoxyadenosines; Disease Models, Animal; Female; Fluorocarbons; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Male; Methylation; Mice; Proteome; Purine-Nucleoside Phosphorylase; Signal Transduction; Thionucleosides | 2016 |
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Nucleus; Dipeptides; Disease Models, Animal; Drosophila melanogaster; Eye; Frontotemporal Dementia; Genes, Insect; Genetic Testing; HeLa Cells; Humans; Methylation; Repetitive Sequences, Amino Acid; RNA Interference | 2016 |
Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
Topics: Adaptation, Physiological; Animals; Cardiomegaly; Cardiomyopathies; Chromatin; Chromatin Assembly and Disassembly; CpG Islands; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Helicases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Gestational Age; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice, Knockout; Myocardium; Myosin Heavy Chains; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Recovery of Function; Signal Transduction; Stress, Physiological; Transcription Factors; Ventricular Function, Left | 2016 |
Role of annexin gene and its regulation during zebrafish caudal fin regeneration.
Topics: Amputation, Surgical; Animal Fins; Animals; Annexins; Blotting, Western; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Histones; Lysine; Methylation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Regeneration; Zebrafish | 2016 |
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; MCF-7 Cells; Methylation; Mice; Mice, Nude | 2016 |
Lysine deacetylase inhibition attenuates hypertension and is accompanied by acetylation of mineralocorticoid receptor instead of histone acetylation in spontaneously hypertensive rats.
Topics: Acetylation; Age Factors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hypertension; Immediate-Early Proteins; Methylation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; RNA Polymerase II; Transcription Factors; Valproic Acid | 2016 |
Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure.
Topics: Animals; Caspase 3; Disease Models, Animal; DNA Methylation; Ethanol; Female; Free Radicals; Gene Expression Regulation, Developmental; Hippocampus; Histones; Methylation; Mice; Oxidative Stress; Pregnancy; Wnt Proteins | 2016 |
Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals.
Topics: Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; DNA; Hedgehog Proteins; Histone-Lysine N-Methyltransferase; Humans; Kruppel-Like Transcription Factors; Methylation; Mice; Neoplasm Metastasis; Nerve Tissue Proteins; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Signal Transduction; Zinc Finger Protein Gli3 | 2016 |
S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adiposity; Animals; CCAAT-Enhancer-Binding Proteins; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; HeLa Cells; Histones; Humans; Male; Methylation; Mice; Obesity; Phosphorylation; PPAR gamma; Protein Processing, Post-Translational; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Transcription, Genetic; Transfection; Wnt Proteins; Wnt Signaling Pathway | 2016 |
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Disease Models, Animal; DNA-Binding Proteins; F-Box Proteins; Female; Gene Expression Regulation, Leukemic; Heterografts; High-Throughput Nucleotide Sequencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intercellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Transcription Factors | 2016 |
The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Elapid Venoms; Gene Expression Regulation, Developmental; Genotype; Histone-Lysine N-Methyltransferase; Histones; Kinetics; Methylation; Mice, Inbred C57BL; Mice, Knockout; Muscle Development; Muscle, Skeletal; Muscular Diseases; Phenotype; Regeneration; Satellite Cells, Skeletal Muscle; Signal Transduction | 2016 |
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Interleukin-3 Receptor alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Knockout; Protein Binding; Tamoxifen | 2016 |
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Mutation; Neoplastic Stem Cells; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2017 |
Increased apoptosis and abnormal visual behavior by histone modifications with exposure to para-xylene in developing Xenopus.
Topics: Acetylation; Animals; Apoptosis; Avoidance Learning; Developmental Disabilities; Disease Models, Animal; Freezing Reaction, Cataleptic; Glucuronates; Histone Code; Histones; Methylation; Neuroprotective Agents; Superior Colliculi; Visual Perception; Xenopus laevis; Xylenes | 2016 |
Protein arginine methylation facilitates KCNQ channel-PIP2 interaction leading to seizure suppression.
Topics: Animals; Arginine; Disease Models, Animal; Epilepsy; KCNQ Potassium Channels; Methylation; Mice, Inbred C57BL; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2016 |
Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress.
Topics: 5-Methylcytosine; Animals; Chromatin Immunoprecipitation; Disease Models, Animal; Epigenesis, Genetic; Female; Gene Ontology; Hippocampus; Male; Methylation; Mice; Mice, Inbred C57BL; Sex Factors; Stress, Psychological | 2016 |
Hypermethylation of the CaSR and VDR genes in the parathyroid glands in chronic kidney disease rats with high-phosphate diet.
Topics: Animals; Chronic Disease; Disease Models, Animal; DNA Methylation; Gene Expression; Hyperparathyroidism, Secondary; Kidney Diseases; Male; Methylation; Parathyroid Glands; Phosphorus, Dietary; Proteins; Rats; Rats, Wistar; Receptors, Calcitriol; Receptors, Calcium-Sensing; RNA, Messenger | 2016 |
DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis.
Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epithelial-Mesenchymal Transition; Gene Silencing; Histones; Homeodomain Proteins; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Methylation; Mice; Neoplasm Metastasis; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Kinase C-alpha; Repressor Proteins; RNA Interference; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger E-box Binding Homeobox 2 | 2016 |
Modulation of FABP4 hypomethylation by DNMT1 and its inverse interaction with miR-148a/152 in the placenta of preeclamptic rats and HTR-8 cells.
Topics: Animals; Cytokines; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Fatty Acid-Binding Proteins; Female; Lipid Metabolism; Methylation; MicroRNAs; NG-Nitroarginine Methyl Ester; Placenta; Pre-Eclampsia; Pregnancy; Promoter Regions, Genetic; Rats, Sprague-Dawley; Up-Regulation | 2016 |
Adenosine 5'-monophosphate blocks acetaminophen toxicity by increasing ubiquitination-mediated ASK1 degradation.
Topics: Acetaminophen; Adenosine Monophosphate; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase Kinase 5; Methylation; Mice, Inbred C57BL; Protective Agents; Proteolysis; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Time Factors; Ubiquitination | 2017 |
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
Topics: Animals; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Humans; Immunologic Memory; Inflammation; Interleukin-2; Lymphocyte Activation; Methylation; Mice; NF-kappa B; Protein-Arginine N-Methyltransferases; T-Lymphocytes, Helper-Inducer; Th1 Cells; Th2 Cells; Up-Regulation | 2017 |
Early-Life Social Isolation-Induced Depressive-Like Behavior in Rats Results in Microglial Activation and Neuronal Histone Methylation that Are Mitigated by Minocycline.
Topics: Animals; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Food Preferences; Hippocampus; Histone-Lysine N-Methyltransferase; Histones; Immobility Response, Tonic; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Microfilament Proteins; Microglia; Minocycline; Rats; Receptors, AMPA; Receptors, Immunologic; Receptors, N-Methyl-D-Aspartate; Social Isolation | 2017 |
Salmonella enterica Serovar Typhi Lipopolysaccharide O-Antigen Modification Impact on Serum Resistance and Antibody Recognition.
Topics: Animals; Antibodies, Bacterial; Bacterial Proteins; Base Sequence; Disease Models, Animal; Female; Gene Expression Regulation, Bacterial; Humans; Immune Sera; Immunization; Methylation; Mice; O Antigens; Operon; Salmonella typhi; Typhoid Fever | 2017 |
Involvement of histone methylation in macrophage apoptosis and unstable plaque formation in methionine-induced hyperhomocysteinemic ApoE
Topics: Animals; Apolipoproteins E; Apoptosis; Disease Models, Animal; Histones; Hyperhomocysteinemia; Methionine; Methylation; Mice; Mice, Knockout; Plaque, Atherosclerotic | 2017 |
Wolf-Hirschhorn syndrome candidate 1-like 1 epigenetically regulates nephrin gene expression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Cytoskeletal Proteins; Disease Models, Animal; Doxorubicin; Epigenesis, Genetic; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Mice, Inbred BALB C; Mice, Inbred C57BL; Nephrotic Syndrome; Nuclear Proteins; Podocytes; Promoter Regions, Genetic; RNA Interference; Transfection; Zebrafish; Zebrafish Proteins | 2017 |
MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response.
Topics: Animals; Cells, Cultured; Chromatin Immunoprecipitation; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Lipopolysaccharides; Macrophages, Peritoneal; Methylation; Mice; Shock, Septic; THP-1 Cells; Trans-Activators; Transcription Factor RelA | 2017 |
Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
Topics: Animals; CD11a Antigen; CD27 Ligand; Cell Separation; Cells, Cultured; Disease Models, Animal; Doxycycline; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Interferons; Lupus Erythematosus, Systemic; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Oligonucleotide Array Sequence Analysis; Repressor Proteins; RNA, Messenger; T-Lymphocytes | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
Species-specific transcription in mice carrying human chromosome 21.
Topics: Animals; Base Sequence; Cell Nucleus; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Gene Expression Regulation; Hepatocyte Nuclear Factors; Hepatocytes; Histones; Humans; Methylation; Mice; Oligonucleotide Array Sequence Analysis; Regulatory Sequences, Nucleic Acid; Species Specificity; Transcription Initiation Site; Transcription, Genetic | 2008 |
Reconstructing the disease model and epigenetic networks for MLL-AF4 leukemia.
Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | 2008 |
Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding.
Topics: Acetylation; Acute Disease; Alcoholism; Animals; Central Nervous System Depressants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Epigenesis, Genetic; Ethanol; Gene Expression Regulation; Hepatocytes; Histones; Intercellular Signaling Peptides and Proteins; Liver; Male; Methylation; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Rats, Wistar | 2009 |
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Endotoxemia; Isoquinolines; Lipopolysaccharides; Methylation; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Methyltransferases; Protein Phosphatase 2; Protein Phosphatase 2C; Protein Processing, Post-Translational; Receptor, Adenosine A1; Sulfonamides; Time Factors; Troponin I | 2009 |
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model.
Topics: Analysis of Variance; Animal Feed; Animals; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Female; Homocystine; Hyperhomocysteinemia; Kidney; Liver; Methionine; Methylation; Rats; Rats, Wistar; S-Adenosylmethionine; Statistics, Nonparametric; Tissue Distribution | 2009 |
In vitro and murine efficacy and toxicity studies of nebulized SCC1, a methylated caffeine-silver(I) complex, for treatment of pulmonary infections.
Topics: Animals; Anti-Bacterial Agents; Caffeine; Cell Line; Disease Models, Animal; Male; Methane; Methylation; Mice; Mice, Inbred C57BL; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Silver Compounds | 2009 |
Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chromatin; Chromatin Immunoprecipitation; CREB-Binding Protein; Depression; Disease Models, Animal; Dominance-Subordination; Gene Expression; Genome-Wide Association Study; Histones; Imipramine; Male; Methylation; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Social Isolation | 2009 |
Epigenetic regulation of the alternatively activated macrophage phenotype.
Topics: Animals; Chromatin Assembly and Disassembly; Disease Models, Animal; Epigenesis, Genetic; Female; Genetic Markers; Histones; Humans; Interleukin-4; Jumonji Domain-Containing Histone Demethylases; Macrophage Activation; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Schistosoma mansoni; Schistosomiasis mansoni; Signal Transduction; STAT6 Transcription Factor; Transcriptional Activation | 2009 |
Relationship between structure and adjuvanticity of N,N,N-trimethyl chitosan (TMC) structural variants in a nasal influenza vaccine.
Topics: Acetylation; Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Viral; Chemistry, Pharmaceutical; Chitosan; Disease Models, Animal; Drug Compounding; Female; Immunization Schedule; Immunoglobulin A, Secretory; Immunoglobulin G; Influenza A virus; Influenza Vaccines; Methylation; Mice; Mice, Inbred C57BL; Molecular Structure; Nasal Lavage Fluid; Orthomyxoviridae Infections; Structure-Activity Relationship; Time Factors; Vaccines, Inactivated | 2009 |
Decreased arginine methylation and myelin alterations in arsenic exposed rats.
Topics: Analysis of Variance; Animals; Arginine; Arsenic; Arsenic Poisoning; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Methylation; Myelin Sheath; Organ Size; Rats; Rats, Wistar; Time Factors | 2010 |
Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model.
Topics: Action Potentials; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Ganglia, Spinal; In Situ Nick-End Labeling; Methylation; Motor Activity; Muscle, Skeletal; Nerve Regeneration; Neurites; Neurons; Oncogene Protein v-akt; Rats; Rats, Wistar; Recovery of Function; Sciatic Neuropathy; Sensation; Tubulin; Vitamin B 12 | 2010 |
The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine.
Topics: Animal Nutritional Physiological Phenomena; Animals; Disease Models, Animal; Ethanol; Gene Expression; Histones; Liver; Liver Diseases, Alcoholic; Male; Methylation; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; S-Adenosylmethionine | 2010 |
L-methionine decreases dendritic spine density in mouse frontal cortex.
Topics: Animals; Anticonvulsants; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Cell Shape; Dendritic Spines; Disease Models, Animal; Down-Regulation; Drug Interactions; Extracellular Matrix Proteins; Frontal Lobe; GABA Agents; Male; Methionine; Methylation; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Reelin Protein; Schizophrenia; Serine Endopeptidases; Synapses; Valproic Acid | 2010 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Carbon; Cell Line; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Folic Acid; Humans; Male; Methylation; Mice; Mice, 129 Strain; Mice, Transgenic; S-Adenosylmethionine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin B Deficiency | 2011 |
alpha-Lipoic acid alters post-translational modifications and protects the chaperone activity of lens alpha-crystallin in naphthalene-induced cataract.
Topics: Acetylation; alpha-Crystallins; Animals; Antioxidants; Cataract; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Lens, Crystalline; Methylation; Molecular Chaperones; Naphthalenes; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Thioctic Acid | 2010 |
Cardiac myosin heavy chain gene regulation by thyroid hormone involves altered histone modifications.
Topics: Acetylation; Animals; Binding Sites; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Disease Models, Animal; DNA, Intergenic; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Hyperthyroidism; Hypothyroidism; Methylation; Myocardium; Myosin Heavy Chains; Polymerase Chain Reaction; Promoter Regions, Genetic; Propylthiouracil; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; RNA Precursors; RNA, Messenger; Time Factors; Transcription, Genetic; Triiodothyronine; Ventricular Myosins | 2010 |
Gastroprotective effect and cytotoxicity of carnosic acid derivatives.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Animals; Anti-Ulcer Agents; Antioxidants; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lansoprazole; Male; Methylation; Mice; Plant Components, Aerial; Plant Extracts; Random Allocation; Rosmarinus; Stomach Ulcer; Structure-Activity Relationship | 2011 |
Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor.
Topics: Animals; Behavior, Animal; Benzimidazoles; Cyclopropanes; Cytochrome P-450 Enzyme System; Disease Models, Animal; Essential Tremor; Gene Deletion; Harmaline; Hydroxylation; Methylation; Mibefradil; Mice; Naphthalenes; Receptors, GABA-A; Structure-Activity Relationship; Testosterone | 2011 |
The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Cholestasis, Intrahepatic; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Female; Immunoblotting; Intestine, Small; Liver Failure; Liver Function Tests; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Sodium | 2011 |
Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model.
Topics: alpha-Synuclein; Animals; Astrocytes; Blotting, Western; Brain; Cell Line; Cells, Cultured; Dendrites; Disease Models, Animal; Immunohistochemistry; Methylation; Mice; Mice, Transgenic; Microglia; Neurodegenerative Diseases; Neurons; Phosphoprotein Phosphatases; Phosphorylation; Serotonin | 2011 |
Can the rat be used as a valid model of human esophageal adenocarcinoma?
Topics: Adenocarcinoma; Animals; Barrett Esophagus; CpG Islands; Disease Models, Animal; Esophageal Neoplasms; Esophagus; Gastroesophageal Reflux; Humans; Methylation; Rats | 2012 |
Intrauterine growth restriction leads to changes in sulfur amino acid metabolism, but not global DNA methylation, in Yucatan miniature piglets.
Topics: Amino Acids, Sulfur; Animals; Animals, Inbred Strains; Animals, Newborn; Betaine-Homocysteine S-Methyltransferase; Cystathionine gamma-Lyase; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; Humans; Liver; Male; Methylation; Organ Size; RNA, Messenger; Swine; Swine, Miniature; Taurine | 2012 |
Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer-membrane protein OmpL32.
Topics: Animals; Bacterial Proteins; Cricetinae; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Kidney; Leptospira interrogans; Leptospirosis; Liver; Methylation; Microscopy, Fluorescence; Porins; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha | 2012 |
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Topics: Animals; Carrier Proteins; Cell Cycle; Cell Line; Chromatin; Congenital Microtia; Crystallography, X-Ray; Disease Models, Animal; DNA Replication; Dwarfism; Ear; Growth Disorders; Histones; Humans; Lysine; Methylation; Micrognathism; Models, Molecular; Origin Recognition Complex; Patella; Protein Structure, Tertiary; Replication Origin; Zebrafish; Zebrafish Proteins | 2012 |
Epigenetic bystander-like effects of stroke in somatic organs.
Topics: Acetylation; Animals; Bystander Effect; Disease Models, Animal; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Histones; Kidney; Liver; Male; Methyl-CpG-Binding Protein 2; Methylation; MicroRNAs; Myocardium; Rats; Rats, Long-Evans; Stroke | 2012 |
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
Topics: Acute Disease; Animals; Arginase; Arginine; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Male; Methylation; Multiple Sclerosis; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2012 |
Novel mutations target distinct subgroups of medulloblastoma.
Topics: Animals; Antigens, CD; beta Catenin; Cadherins; Cdh1 Proteins; Cell Cycle Proteins; Cell Lineage; Cerebellar Neoplasms; Child; Class I Phosphatidylinositol 3-Kinases; CREB-Binding Protein; DEAD-box RNA Helicases; Disease Models, Animal; DNA Copy Number Variations; DNA Helicases; DNA Mutational Analysis; Genome, Human; Genomics; Hedgehog Proteins; Histone Demethylases; Histones; Humans; Medulloblastoma; Methylation; Mice; Mutation; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Transcription Factors; Wnt Proteins | 2012 |
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
Topics: Animals; Biomarkers; Choline; Cysteine; Disease Models, Animal; Folic Acid Deficiency; Heterozygote; Homocysteine; Isoenzymes; Liver; Male; Methionine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis, Insertional; Mutant Proteins; Random Allocation | 2013 |
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine | 2013 |
Transcription elongation and tissue-specific somatic CAG instability.
Topics: Animals; Chromatin; Corpus Striatum; Disease Models, Animal; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Organ Specificity; Transcription, Genetic; Trinucleotide Repeat Expansion | 2012 |
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Indoles; Methylation; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Sulfonamides; Vemurafenib | 2013 |
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex | 2013 |
Cerebral postischemic reperfusion-induced demethylation of the protein phosphatase 2A catalytic subunit.
Topics: Animals; Brain Ischemia; Catalytic Domain; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Hippocampus; Immunohistochemistry; Methylation; Mitogen-Activated Protein Kinases; Neurons; Phosphoprotein Phosphatases; Protein Isoforms; Protein Phosphatase 2; Rats; Rats, Wistar; Reperfusion Injury; Ribosomal Protein S6 Kinases; Telencephalon | 2002 |
L-methionine supplementation accelerates tumour growth and shifts the phospholipid derivative pattern in a murine model of malignant melanoma. A proton HRMAS NMR spectroscopy study.
Topics: Animals; Cell Division; Dietary Supplements; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Melanoma; Methionine; Methylation; Mice; Mice, Inbred C57BL; Phospholipids | 2002 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis | 2003 |
Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo.
Topics: Acylation; Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Disease Models, Animal; Drug Screening Assays, Antitumor; Flavonoids; Humans; Indonesia; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Male; Methylation; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Prostatic Neoplasms; Tumor Cells, Cultured; Vitex | 2003 |
Antagonism of hypervitaminosis A-induced anterior neural tube closure defects with a methyl-donor deficiency in murine whole-embryo culture.
Topics: Animals; Diet; Disease Models, Animal; Embryonic and Fetal Development; Female; Hypervitaminosis A; Male; Methylation; Mice; Mice, Inbred ICR; Neural Tube Defects; Organ Culture Techniques; Pregnancy; Rats | 2003 |
Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes.
Topics: Adenoviruses, Human; Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Gene Expression Profiling; Humans; Injections, Intramuscular; Mesocricetus; Methylation; Mice; Neoplasms, Experimental; Neuroectodermal Tumors; Oligonucleotide Array Sequence Analysis; Peritoneal Cavity; Proteins; Sequence Analysis, DNA; Transcription, Genetic; Viral Proteins; Virus Integration | 2003 |
Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.
Topics: Amino Acid Motifs; Animals; Base Sequence; Binding Sites; Catalytic Domain; Cell Nucleus; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Chromatin; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Gene Expression Regulation, Enzymologic; Glucose-6-Phosphatase; Homeodomain Proteins; Islets of Langerhans; Luciferases; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Paired Box Transcription Factors; PAX6 Transcription Factor; Plasmids; Polymerase Chain Reaction; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Rats; Repressor Proteins; Salts; Subcellular Fractions; Trans-Activators; Transcription, Genetic | 2004 |
Temporal evaluation of methionine synthase and related metabolites in the MAC15A mouse adenocarcinoma animal model.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma; Cell Division; Disease Models, Animal; Disease Progression; Humans; Methionine; Methylation; Mice | 2004 |
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
Topics: Acetylation; Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Phenylbutyrates; Trinucleotide Repeat Expansion; Ubiquitin | 2005 |
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid | 2005 |
The effects of carboxymethylated chitosan on metalloproteinase-1, -3 and tissue inhibitor of metalloproteinase-1 gene expression in cartilage of experimental osteoarthritis.
Topics: Acids; Animals; Antirheumatic Agents; Cartilage, Articular; Chitosan; Disease Models, Animal; Gene Expression; Injections, Intra-Articular; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Methylation; Molecular Weight; Osteoarthritis; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2005 |
Oncogene-induced senescence as an initial barrier in lymphoma development.
Topics: ADP-Ribosylation Factors; Animals; Apoptosis; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; Chromosomal Instability; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, ras; Heterochromatin; Lymphoma; Methylation; Methyltransferases; Mice; Mice, Transgenic; Precancerous Conditions; Repressor Proteins; Transgenes; Tumor Suppressor Protein p53 | 2005 |
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.
Topics: Acetylation; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chromatin; Depression; Disease Models, Animal; Hippocampus; Histones; Imipramine; Male; Methylation; Mice; Mice, Inbred C57BL; Stress, Psychological | 2006 |
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.
Topics: Aged; Aged, 80 and over; Animals; Arginine; Astrocytes; Blotting, Western; Citrulline; Disease Models, Animal; Down-Regulation; Female; Glaucoma, Open-Angle; Humans; Hydrolases; Immunohistochemistry; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Optic Nerve Diseases; Proteomics; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
Topics: Animals; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models, Animal; DNA Damage; Glioblastoma; Guanine; Humans; Methylation; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Methylation; Mice; Mice, Nude; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Structure-Activity Relationship; Thyroid Neoplasms; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2006 |
Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome.
Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Gene Expression Regulation; Male; Methyl-CpG-Binding Protein 2; Methylation; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Protein Binding; Rett Syndrome; Stress, Physiological; Transcription, Genetic; Tyrosine | 2006 |
Proteomic analysis of hepatic iron overload in mice suggests dysregulation of urea cycle, impairment of fatty acid oxidation, and changes in the methylation cycle.
Topics: Animals; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Enzymes; Fatty Acids; Iron Compounds; Iron Overload; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Proteomics; Severity of Illness Index; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urea | 2007 |
Modulation of nucleosome dynamics in Huntington's disease.
Topics: Acetylation; Animals; Brain; Chromomycins; Disease Models, Animal; Female; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Plicamycin; Transcription, Genetic | 2007 |
Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CCl4 in the rat.
Topics: Acute Disease; Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Liver Diseases; Male; Methylation; Molecular Structure; Rats; Rats, Wistar; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Mice deficient in cystathionine beta synthase display altered homocysteine remethylation pathway.
Topics: Animals; Cystathionine beta-Synthase; Disease Models, Animal; Homocysteine; Homocystinuria; Methylation; Mice; MicroRNAs | 2007 |
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.
Topics: Acylation; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; BALB 3T3 Cells; Biotransformation; Body Weight; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Kidney Diseases; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Transgenic; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Tissue Distribution | 2007 |
Epigenetic mechanisms regulate Mallory Denk body formation in the livers of drug-primed mice.
Topics: Acetylation; Animals; Carcinogens; Cell Fractionation; Cell Nucleus; Disease Models, Animal; Drug Antagonism; Drug Combinations; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hepatocytes; Histones; Liver; Male; Methylation; Mice; Mice, Inbred C3H; Oligonucleotide Array Sequence Analysis; Proteins; RNA, Messenger; S-Adenosylmethionine | 2008 |
Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Chromatin Immunoprecipitation; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Methylation; Ovariectomy; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2008 |
Striatal histone modifications in models of levodopa-induced dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylation; Animals; Chromatin; Chromosome Aberrations; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Female; Histones; Levodopa; Macaca mulatta; Male; Methylation; Mice; Mice, Inbred C57BL; Parkinsonian Disorders; Phosphorylation; Protein Processing, Post-Translational; Species Specificity | 2008 |
Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cercopithecus; Disease Models, Animal; Folic Acid; Haplorhini; Macaca fascicularis; Methylation; Methyltransferases; Nerve Tissue; Nitrous Oxide; Peripheral Nervous System Diseases; Spinal Cord Diseases; Vitamin B 12 Deficiency | 1980 |
Increased phospholipid methylation in the myocardium of hyperthyroid rats.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Hyperthyroidism; Male; Methylation; Microsomes; Myocardium; Phospholipids; Rats; S-Adenosylmethionine; Thyroxine | 1980 |
Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
Topics: Adenosine Deaminase; Animals; Animals, Newborn; Base Sequence; Cell Death; Disease Models, Animal; DNA Primers; Embryonic and Fetal Development; Female; Gene Targeting; Homozygote; Humans; Intestine, Small; Liver; Male; Methylation; Mice; Molecular Sequence Data; Mutation; Pregnancy; Pulmonary Atelectasis; Purines; Severe Combined Immunodeficiency; T-Lymphocyte Subsets | 1995 |
[Histologic and cell kinetic alteration of gastric mucosa under continuous duodenal regurgitation in experimental dog model].
Topics: Animals; Atrophy; Bromodeoxyuridine; Cell Cycle; Disease Models, Animal; DNA; Dogs; Gastric Mucosa; Gastroesophageal Reflux; Hyperplasia; Male; Methylation | 1994 |
Lung tumors in strain A mice: application for studies in cancer chemoprevention.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Disease Models, Animal; DNA; DNA Damage; Drug Screening Assays, Antitumor; Female; Isothiocyanates; Lung Neoplasms; Male; Methylation; Mice | 1993 |
Synthesis and muscarinic activities of 3-(pyrazolyl)-1,2,5,6-tetrahydropyridine derivatives.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Analysis of Variance; Animals; Binding, Competitive; Disease Models, Animal; Dopamine Agents; Isotope Labeling; Male; Memory; Methylation; Mice; Miosis; Muscarinic Agonists; Muscarinic Antagonists; Mydriasis; Oxotremorine; Pirenzepine; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Salivation; Structure-Activity Relationship; Vas Deferens | 1996 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
Topics: Animals; Aorta; Brain; Chronic Disease; Cystathionine beta-Synthase; Disease Models, Animal; Endothelium, Vascular; Folic Acid; Food, Fortified; Heterozygote; Homocysteine; Hyperhomocysteinemia; In Vitro Techniques; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; S-Adenosylhomocysteine; S-Adenosylmethionine; Thrombomodulin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2001 |
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes | 2002 |
Alcohol interference with the folate enterohepatic cycle.
Topics: Alcoholism; Animals; Bile; Disease Models, Animal; Enterohepatic Circulation; Female; Folic Acid; Folic Acid Deficiency; Humans; Liver; Methylation; Oxidation-Reduction; Rats | 1977 |
Effects of alcohol consumption on DNA methylation reactions and gene expression: implications for increased cancer risk.
Topics: Animals; Cocarcinogenesis; Disease Models, Animal; DNA Damage; ErbB Receptors; Ethanol; Evaluation Studies as Topic; Gene Expression; Humans; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogenes; Rats; Rats, Sprague-Dawley; Risk Factors | 1992 |
Methylated lysine in storage body protein of sheep with hereditary ceroid-lipofuscinosis.
Topics: Amino Acids; Animals; Brain; Chromatography, Ion Exchange; Chromatography, Thin Layer; Disease Models, Animal; Liver; Lysine; Methylation; Microscopy, Electron; Neuronal Ceroid-Lipofuscinoses; Pancreatin; Proteins; Sheep; Spectrometry, Mass, Fast Atom Bombardment | 1992 |
Antigen induced arthritis in beige (Chediak-Higashi) mice.
Topics: Animals; Antigens; Arthritis; Autoradiography; Cartilage, Articular; Disease Models, Animal; Joints; Male; Methylation; Mice; Mice, Mutant Strains; Peptide Hydrolases; Serum Albumin, Bovine | 1990 |
Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.
Topics: Animals; Arginine; Brain Diseases; Chiroptera; Cycloleucine; Disease Models, Animal; Liver; Methylation; Myelin Basic Protein; Rats; Rats, Inbred Strains; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Human leukemic cells: cytochemical studies on nuclear proteins.
Topics: Animals; Cell Line; Cell Nucleus; Cells, Cultured; Cricetinae; Disease Models, Animal; DNA; Female; Genes; Histocytochemistry; Histones; Humans; Infectious Mononucleosis; Leukemia, Lymphoid; Lymphocytes; Male; Methylation; Staining and Labeling | 1972 |
The effect of staphylococcal enterotoxin on the epithelial mucosubstances of the small intestine of rhesus monkeys.
Topics: Animals; Disease Models, Animal; Enteritis; Enterotoxins; Epithelium; Haplorhini; Histocytochemistry; Intestinal Mucosa; Methylation; Microscopy, Electron; Mucins; Staining and Labeling | 1970 |
Experimental fibrosing alveolitis.
Topics: Animals; Cricetinae; Disease Models, Animal; Injections, Subcutaneous; Methylation; Microscopy, Electron; Nitroso Compounds; Pulmonary Fibrosis; Time Factors; Urethane | 1972 |
Bile salts of spontaneously atherosclerosis-susceptible white Carneau pigeon.
Topics: Animals; Arteriosclerosis; Bile; Bile Acids and Salts; Bird Diseases; Chromatography, Gas; Chromatography, Thin Layer; Columbidae; Disease Models, Animal; Feces; Male; Methylation; Species Specificity; Taurine | 1971 |