isomethyleugenol has been researched along with Disease Exacerbation in 164 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (3.05) | 18.2507 |
| 2000's | 28 (17.07) | 29.6817 |
| 2010's | 76 (46.34) | 24.3611 |
| 2020's | 55 (33.54) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Chen, S; Chen, Z; Hu, X; Hu, Y; Lu, M; Pan, B; Shen, X; Shi, X; Sun, X; Tong, X; Xue, X | 1 |
| Ji, T; Liu, A; Mao, X; Weng, Y | 1 |
| Chen, X; Dong, J; Gong, W; Guo, B; Jiang, Q; Qin, J; Shao, X; Shen, S; Shi, T; Shi, Y; Zhang, L | 1 |
| Chen, L; Jin, Y; Li, L; Ma, C; Ma, Y; Tang, Y; Xing, M; Yang, D; Yang, J; Zhang, M | 1 |
| Gao, C; Li, H; Liu, C; Ma, X; Sun, C; Yu, H; Zhuang, J | 1 |
| Chen, K; Chen, Y; Li, Y; Liao, N; Liu, J; Luo, M; Mo, Z; Wang, M; Xiao, J; Zeng, J; Zhang, Q; Zou, J | 1 |
| Antonescu, CR; Bale, T; D'Angelo, SP; Dermawan, JK; Singer, S; Tap, WD; Villafania, L | 1 |
| Bates, M; Campbell, S; Carey, LA; Considine, M; Cope, L; Fackler, MJ; Forero-Torres, A; Ingle, JN; Lin, NU; Marla, S; Nanda, R; Sokoll, L; Storniolo, AM; Sukumar, S; Tulac, S; Umbricht, CB; Venkatesan, N; Visvanathan, K; Wolff, AC; Wu, NC | 1 |
| Clark, P; Dong, F; Fouts, A; Gottlieb, P; Herold, KC; Pyle, L; Simmons, KM; Steck, AK; Usmani-Brown, S; Yu, L | 1 |
| Cui, Y; Dai, M; Hu, Y; Kong, W; Wang, X; Wu, H; Wu, J; Yu, B; Yu, X; Zhang, H; Zheng, Y | 1 |
| Chen, J; Cui, J; Fallon, MB; Gao, Y; Guha, S; Quan, M; Xie, D; Xie, K | 1 |
| Chen, J; Chen, S; Fan, S; Fang, X; Fang, Y; Liu, G; Ma, J; Shen, P; Shen, S; Wang, S; Wu, H; Wu, Y; Xie, Z; Yang, Y | 1 |
| Feng, D; Gao, J; Gao, T; Hou, Y; Huang, W; Leng, S; Liu, R; Liu, W; Qiu, R; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zhang, K; Zhang, X; Zheng, Y | 1 |
| Gui, X; Jia, S; Jiang, X; Li, J; Li, T; Li, X; Lu, D; Lu, Y; Meng, Q; Pu, H; Song, S; Wang, C; Wang, L; Xin, X; Xu, J; Yang, Y; Zhang, W | 1 |
| Cao, Y; Cui, L; Ding, T; He, X; Lu, H; Shi, Q; Tian, Z; Xia, W; Xu, R; Xue, D; Yang, H; Zhou, Y | 1 |
| Chen, X; Hao, X; Huang, J; Lan, T; Li, H; Li, J; Liao, H; Liao, M; Liu, H; Wu, H; Xie, K; Xu, L; Yan, X; Yuan, K; Zeng, Y; Zhang, D | 1 |
| Devaux, Y; Nossent, AY | 1 |
| Fang, J; Li, F; Li, Z; Peng, Y; Zhou, J | 1 |
| Hwang, JW; Hwang, KT; Jang, CY; Kim, NH; Kim, S; Kim, YA; Kim, YK; Myung, N; Park, JE | 1 |
| Muthusamy, S | 1 |
| Chen, Y; Gui, X; Jia, S; Jiang, X; Li, J; Li, T; Li, X; Lu, D; Lu, Y; Meng, Q; Pu, H; Song, S; Wang, C; Wang, L; Xie, S; Xin, X; Xu, J; Yang, Y | 1 |
| Hou, T; Li, M; Li, Y; Li, Z; Liu, C; Liu, X; Lu, X; Mao, Z; Tang, M; Wang, H; Wen, H; Yang, Q; Yang, Y; Zhao, Y; Zhu, Q; Zhu, WG | 1 |
| Lin, C; Ye, J; Zhuang, J | 1 |
| Liu, JY; Wellen, KE | 1 |
| Chu, JW; Im, H; Kim, H; Lee, JM; Park, IG; Park, SC; Song, H | 1 |
| Dai, C; Ding, H; Jia, C; Su, Y; Zhang, X | 1 |
| Liang, S; Ni, J; Ren, Y; Shan, B; Tian, W; Wang, H | 1 |
| Ban, Y; Cai, J; Hu, M; Li, G; Li, J; Li, X; Mei, Y; Tan, P; Tan, Y; Xiang, B; Xiong, W; Yi, M; Zeng, Z; Zhou, Y | 1 |
| Chen, B; Chen, Y; Deng, Y; Ge, J; Gui, T; Guo, C; Hu, R; Ju, J; Li, J; Li, Q; Li, X; Liu, M; Ma, L; Wang, Y; Wu, X; Xu, P; Yang, D; Yao, B; Yu, Z; Zeng, X; Zhao, Q | 1 |
| Chen, H; Chen, W; Ge, J; Guo, L; Hou, G; Mao, Q; Yang, J; Zhang, X | 1 |
| Cong, R; Ji, CJ; Luan, JC; Song, LB; Song, NH; Xia, JD; Zhang, QJ; Zhou, X | 1 |
| Wu, Y; Xu, Y | 1 |
| Chai, P; Fan, J; Fan, X; Ge, S; Jia, R; Ni, H; Wang, S; Wang, Y; Xing, Y; Yu, J | 1 |
| Chen, Q; Ji, C; Lin, K; Miao, L; Xu, A; Yang, J; Yang, L; Yu, Y; Zhang, X | 1 |
| Gaikwad, AB; Kale, A; Sankrityayan, H; Sharma, N | 1 |
| Chen, YC; Huang, GZ; Lv, XZ; Shao, TR; Wu, QQ; Zeng, WS; Zheng, ZN | 1 |
| Chen, Q; Lou, W; Pu, N; Wu, W; Yin, H; Zhang, J; Zhao, G | 1 |
| Huang, W; Li, P; Qiu, X | 1 |
| Li, X; Mao, L; Zhang, J; Zhang, Y | 1 |
| Huang, T; Jiang, G; Lyu, L; Xiang, W; Yuan, J; Zhang, C; Zheng, F | 1 |
| Chang, Z; Li, Z; Liu, Y; Lu, X; Luo, C; Qiao, K; Sun, T; Xu, Z; Yang, C; Zhang, C; Zhang, H | 1 |
| Asberry, AM; Beketova, E; Chen, X; Deng, X; Elzey, BD; Fang, S; Hu, CD; Huang, J; Li, C; Liu, S; Malola, J; Owens, JL; Pili, R; Ratliff, TL; Wan, J; Zhang, Q | 1 |
| Huo, FC; Pei, DS; Zhu, ZM | 1 |
| Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W | 1 |
| Chen, S; Cheng, X; Fang, W; Hao, H; Hu, X; Hua, F; Huang, D; Huang, Z; Li, Q; Liu, F; Luo, Z; Xiao, F; Zhang, X | 1 |
| He, Z; Li, Z; Zhang, C; Zhou, S; Zhu, Y | 1 |
| Gao, Y; Gao, Z; Luo, J; Song, W; Yang, K | 1 |
| Luo, Z; Miao, Z; Wei, H; Wu, F; Wu, K; Zhang, J | 1 |
| Hara, A; Inoue, F; Kukita, A; Osuga, Y; Sone, K; Taguchi, A; Takahashi, Y; Tanikawa, M; Toyohara, Y; Tsuruga, T | 1 |
| Paramasivam, A; Priyadharsini, JV | 1 |
| Chen, B; Davis, MJ; Deng, Y; Gui, T; Herold, MJ; Hu, R; Huang, DCS; Jiang, ZW; Ju, J; Li, H; Li, Q; Li, X; Liu, M; Pan, HF; Wang, J; Wang, Y; Wang, Z; Xu, P; Yang, D; Yao, B; Zen, K; Zeng, X; Zhao, Q | 1 |
| Chong, T; Guan, Y; Ma, Y; Xu, F; Xue, L; Yang, X; Zhang, P | 1 |
| Oudenaarden, C; Pietras, K; Sjölund, J | 1 |
| Cheng, X; Ma, Z; Pan, J; Shangguan, X; Wang, Q; Xin, Z; Xue, W; Yue, T; Zhang, W | 1 |
| Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z | 1 |
| Liu, Y; Ou, B; Xu, X; Yan, Y; Yang, X; Zhang, J | 1 |
| Chen, D; Feng, P; Guo, W; Li, J; Li, M; Wang, X; Xia, Y; Zhang, C | 1 |
| Chen, YT; Chu, XY; Xiang, D; Zhao, XY | 1 |
| Jiang, W; Kong, XY; Luo, Z; Qin, GJ; Tang, HY; Xu, QL; Zhang, B; Zhang, RY | 1 |
| Abisambra, JF; Alvarez, VE; Ash, PEA; Boudeau, S; Cheng, JX; Crary, JF; Cruz, AL; Emili, A; Hovde, S; Jiang, L; Kanaan, N; Kuo, MH; Kwan, J; Lei, S; Li, H; Lin, W; Maziuk, BF; Murray, ME; Petrucelli, L; Song, J; van Vliet, E; Verma, M; Wolozin, B; Yang, Z; Zhang, C; Zhao, J | 1 |
| Chen, T; Cui, M; Cui, Y; Ge, C; Huo, Q; Li, H; Li, J; Sun, J; Tian, H; Xie, H; Yao, M; Zhao, F | 1 |
| Bartom, E; Bi, Y; Burant, CF; Calvert, AE; Chalastanis, A; Chandel, NS; Davuluri, RV; Dubrovskyi, O; Horbinski, C; Hua, Y; Hurley, LA; James, CD; Kachman, M; Kouri, FM; May, JL; Mazar, AP; Mishra, RK; Peter, ME; Schiltz, GE; Stegh, AH; Wu, Y; Zheng, H | 1 |
| Fukayama, M; Hiraoka, N; Kawai, A; Komiyama, M; Makise, N; Nakatani, F; Yonemori, K; Yoshida, A | 1 |
| Cheng, Z; Ding, Y; Qi, L; Tang, N; Zhang, W | 1 |
| Li, T; Liu, Y; Shi, Y; Wang, L; Wang, T; Wang, X; Wang, Y; Yang, Y | 1 |
| Chen, L; Deng, R; Jin, Y; Lavillette, D; Li, B; Li, D; Liang, R; Lui, K; Nie, J; Pan, W; Qian, Z; Shan, J; Shan, Z; Sun, B; Tsun, A; Xiong, R; Xu, K; Zhao, B; Zhao, H | 1 |
| Darwish, HA; Diab, I; Helmy, MW; Motawi, TK; Noureldin, MH | 1 |
| Chen, Z; He, J; Li, J; Li, Y; Lu, Z; Luo, M; Shi, X; Sun, N; Yang, W; Zhou, C | 1 |
| Ismail, T; Kim, C; Kwon, T; Lee, HK; Lee, HS; Park, TJ | 1 |
| Kaneko, S; Li, X | 1 |
| He, L; Li, J; Wang, X; Xie, H; Xie, L; Yan, H; Ying, Y; Zheng, X | 1 |
| Chen, G; Gan, BL; He, RQ; Hu, XH; Wei, DM; Zhang, Y | 1 |
| Chen, T; Han, X; Ren, G; Tang, J | 1 |
| Li, P; Liu, C; Liu, H; Ma, Y; Yu, T | 1 |
| Betz, BL; Brown, NA; Cascalho, M; Cooke, A; Davis, A; El Kadi, N; Hassan, KA; Kalemkerian, GP; Korkaya, H; Vadnala, V; Wang, L | 1 |
| Akiyama, Y; Inokuchi, M; Kojima, K; Nakagawa, M; Okuno, K; Shimada, S; Tanaka, S; Tanioka, T; Yamaoka, S | 1 |
| Platzbecker, U | 1 |
| Baethmann, M; Ballhausen, D; Baumgartner, MR; Blasco-Alonso, J; Blom, H; Boy, N; Bueno, M; Burgos Peláez, R; Cerone, R; Chabrol, B; Chapman, KA; Couce, ML; Crushell, E; Dalmau Serra, J; Diodato, D; Diogo, L; Dionisi-Vici, C; Ficicioglu, C; Froese, DS; García Jimenez, MC; García Silva, MT; Gaspar, AM; Gautschi, M; Gleich, F; González-Lamuño, D; Gouveia, S; Grünewald, S; Hendriksz, C; Huemer, M; Janssen, MCH; Jesina, P; Koch, J; Kölker, S; Konstantopoulou, V; Kožich, V; Lavigne, C; Lund, AM; Martin, CA; Martinelli, D; Martins, EG; Meavilla Olivas, S; Mention, K; Mochel, F; Morris, AA; Mundy, H; Murphy, E; Olivieri, G; Paquay, S; Pedrón-Giner, C; Ruiz Gómez, MA; Santra, S; Schiff, M; Scholl-Bürgi, S; Schwartz, IV; Seifert, B; Servais, A; Skouma, A; Tran, C; Vives Piñera, I; Walter, J; Weisfeld-Adams, J | 1 |
| Chen, B; Li, Y; Song, R; Xu, F; Xue, C | 2 |
| Liu, W; Ning, J; Wu, D; Wu, L; Zhang, D | 1 |
| Cong, P; Hou, H; Jiang, Y; Xu, Y; Yu, X; Zhou, Y | 1 |
| Bavafaye-Haghighi, E; Besenbacher, S; Borre, M; Hoyer, S; Kristensen, H; Mouritzen, P; Orntoft, TF; Rasmussen, AK; Sorensen, KD; Strand, SH | 1 |
| Chen, J; Jia, L; Ma, J; Miao, W; Song, D | 1 |
| Gao, LM; Li, Y; Shi, SS; Tian, Q; Wang, P; Wu, T; Xu, SF; Yin, XB; Zhang, L; Zhao, J; Zheng, L; Zheng, Y | 1 |
| Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM | 1 |
| Golding, A; Hasni, S; Illei, G; Shevach, EM | 1 |
| Benedetti, D; Bomben, R; Caldana, C; D'Arena, G; Dal Bo, M; Del Poeta, G; Di Raimondo, F; Gaidano, G; Gattei, V; Hartmann, TN; Hutterer, E; Pozzato, G; Pozzo, F; Rossi, D; Rossi, FM; Tissino, E; Zaja, F; Zucchetto, A | 1 |
| Berg, LJ; Guan, T; Kaech, SM; Kapoor, V; Shin, HM; Welsh, RM | 1 |
| Chen, Z; Li, Z; Lu, S; Niu, X; Shen, S; Tang, N; Xu, L; Xu, Y; Ye, X | 1 |
| Chen, J; Chowdhury, F; Doğanay, S; Ha, T; Hong, Y; Huang, B; Jia, H; Jia, Q; Li, Y; Lin, LJ; Poh, YC; Seong, J; Singh, R; Tajik, A; Tan, Y; Wang, L; Wang, N; Wang, Y; Wei, F; Wu, DC; Yi, H; Zhang, S; Zhang, Y | 1 |
| Cho, YA; Choe, EJ; Hong, JS; Hong, SD; Hong, SP; Lee, JI; Yoon, HJ | 1 |
| Cui, W; Kong, L; Li, X; Luo, M; Miao, L; Tan, Y; Wu, H; Xu, F; Zhou, S | 1 |
| Chen, K; Chen, L; Ding, H; Du, D; Jiang, H; Jiang, X; Jiao, L; Kong, X; Lian, F; Liu, J; Liu, X; Lu, J; Luo, C; Shen, J; Zhang, N; Zheng, M; Zhu, K | 1 |
| dos Santos, BT; Eisele, B; Ferrari, P; Fijtman, A; Fries, GR; Gassen, NC; Gubert, C; Kapczinski, F; Kauer-Sant'Anna, M; Rein, T; Rüegg, J; Sartori, J; Vasconcelos-Moreno, MP | 1 |
| Augoustides-Savvopoulou, P; Baumgartner, MR; Blair, E; Brennerova, K; Broomfield, A; Bürer, C; De Meirleir, L; Fowler, B; Gökcay, G; Hennermann, J; Huemer, M; Jardine, P; Ješina, P; Koch, J; Kožich, V; Landolt, MA; Lorenzl, S; Lotz-Havla, AS; Noss, J; Parini, R; Peters, H; Plecko, B; Ramos, FJ; Schlune, A; Suormala, T; Tsiakas, K; Zerjav Tansek, M | 1 |
| Brambert, PR; Calafiore, G; Desai, CV; Godley, LA; Hameed, R; Kelpsch, DJ; Raimondi, SL | 1 |
| Chen, YH; Gao, J; Licht, JD; Parimi, V; Popovic, R; Winter, JN; Wolniak, K; Zhou, Z | 1 |
| Chen, J; Fu, X; Fu, Y; Liao, K; Qian, X; Ren, L; Xiao, J | 1 |
| Culmes, M; Eckstein, HH; Gebhard, H; Greißel, A; Napieralski, R; Pelisek, J; Schmitt, M; Wagner, E; Zernecke, A; Zimmermann, A | 1 |
| Gao, L; Kang, HY; Li, MY; Wang, CB; Wang, LL; Wang, W; Wang, XR; Yu, L | 1 |
| Ding, X; Fan, J; Fan, X; Ge, S; He, J; Hoffman, AR; Jia, R; Ni, H; Pan, H; Qian, G; Wen, X; Xing, Y; Zhang, H | 1 |
| Cavicchioli, F; Comino, A; Crook, T; Haley, V; Lackner, M; Lo Nigro, C; Mauri, F; Merlano, M; O'Leary, K; Schmid, P; Shia, A; Walter, K; Wischnewsky, MB | 1 |
| Lee, EJ; Lee, H | 1 |
| Adjaoud, D; Ahmadian, MR; Baruchel, A; Bertrand, Y; Cassinat, B; Cavé, H; Caye, A; Chomienne, C; Contet, A; Dalle, JH; Dvorsky, R; Fenneteau, O; Galambrun, C; Gazal, S; Guidez, F; Häussinger, D; Lachenaud, J; Lainey, E; Méchinaud, F; Nakhaei-Rad, S; Nelken, B; Nouri, K; Paillard, C; Pereira, S; Petit, A; Picard, C; Poirée, M; Reguerre, Y; Sirvent, N; Strullu, M; Verger, E; Vidaud, D; Vivent, J | 1 |
| Cui, Y; Du, J; Li, Y; Liang, S; Wei, L; Xia, Z; Xie, L; Zhang, Y; Zhao, X | 1 |
| Fan, Y; Liu, Y; Mu, X; Qin, Y; Shen, B; Tan, M; Zhang, F | 1 |
| Bradner, JE; Burd, CE; Clark, KS; Fedoriw, Y; Jeck, WR; Liu, JY; Parker, JS; Paulk, J; Qi, J; Sharpless, NE; Simon, JM; Souroullas, GP; Xiong, J | 1 |
| Agathangelidis, A; Anagnostopoulos, A; Baliakas, P; Bele, P; Chartomatsidou, E; Ghia, P; Giassafaki, L; Karamanli, T; Kotta, K; Makris, AM; Moysiadis, T; Ntoufa, S; Papakonstantinou, N; Rosenquist, R; Stamatopoulos, K; Stavroyianni, N; Sutton, LA | 1 |
| Cui, HJ; Huang, MY; Liu, W; Xuan, F | 1 |
| Cai, Q; Casero, RA; Chen, H; Dou, Y; Jin, L; Jin, Y; Li, X; Liu, Y; Lu, J; Luo, H; Qiu, Y; Reisman, D; Seto, E; Shenoy, AK; Tang, M; Wu, L | 1 |
| Rau, T | 1 |
| Dong, W; Jia, L; Li, N; Ma, X; Miao, Y; Su, Z; Zhao, L; Zhou, H | 1 |
| Castellano, D; Costa, C; de la Rosa, F; Duarte, J; Dueñas, M; Fernández-Grajera, M; López-Calderón, FF; Martínez-Fernández, M; Muñoz, HG; Paramio, JM; Rubio, C; Saiz-Ladera, C; Segovia, C; Villacampa, F | 1 |
| Andruck, A; Blume-Peytavi, U; Fimmel, S; Hadam, S; Kottner, J; Pfannes, EKB; Vogt, A | 1 |
| Narayanan, SP; Shukla, S; Singh, S | 1 |
| Cui, Q; He, C; Huang, Y; Li, L; Lu, Z; Qu, Q; Riggs, AD; Shi, H; Shi, Y; Sun, G; Yang, CG; Ye, P | 1 |
| Chiba, H; Nakayama, F; Sawada, N; Semba, S; Usami, Y; Yokozaki, H | 1 |
| Delfraino, B; Hazen, SL; Hu, B; Klein, AL; Levison, BS; Shrestha, K; Tang, WH; Tong, W; Troughton, RW; Wang, Z | 1 |
| Issa, JP | 1 |
| Kim, J; Kim, WH; Lee, SH; Lee, YM | 1 |
| Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J | 1 |
| Aarnio, M; Abdel-Rahman, WM; Bützow, R; Gylling, A; Järvinen, HJ; Mecklin, JP; Nieminen, TT; Nuorva, K; Peltomäki, P; Renkonen-Sinisalo, L | 1 |
| Malcovati, L | 1 |
| Beghin, A; Belin, S; Bezin, L; Brunet-Manquat, S; Diaz, JJ; Dumontet, C; Mertani, HC; Prats, AC; Solano-Gonzàlez, E; Textoris, J | 1 |
| Berger, H; Felsberg, J; Hartmann, C; Heese, O; Krex, D; Loeffler, M; Nikkhah, G; Pietsch, T; Reifenberger, G; Schackert, G; Schramm, J; Simon, M; Steinbach, JP; Tonn, JC; von Deimling, A; Weller, M; Westphal, M; Wiestler, O | 1 |
| Bryant, SC; Garrity-Park, MM; Loftus, EV; Sandborn, WJ; Smyrk, TC | 1 |
| Chen, XR; Li, X; Wang, JW; Ye, ZY; Zhang, H | 1 |
| Argani, P; Brzoska, P; Chang, HY; Gupta, RA; Horlings, HM; Hung, T; Kim, J; Kong, B; Li, R; Rinn, JL; Shah, N; Sukumar, S; Tsai, MC; van de Vijver, MJ; Wang, KC; Wang, Y; West, RB; Wong, DJ | 1 |
| Cheng, Y; Guo, S; Liu, G; Pan, Q; Yang, X | 1 |
| Cabarcas, SM; Crea, F; Danesi, R; Farrar, WL; Hurt, EM; Marquez, VE; Mathews, LA; Sun, L | 1 |
| Beland, FA; Pogribny, IP; Simpson, NE; Tryndyak, VP | 1 |
| Chinnaiyan, AM; He, S; Kato, K; Kuick, R; Liu, Y; Mani, RS; Marquez, VE; Mineishi, S; Mochizuki, K; Nieves, E; Varambally, S; Wang, J; Xie, F; Zhang, Y | 1 |
| Chen, L; Cheng, X; Ji, T; Li, J; Li, Y; Liu, X; Liu, Y; Xiao, Z; Yao, S; Zheng, P; Zhou, J | 1 |
| Armstrong, SA; Khattab, MH; Kluk, MJ; Neff, T; Orkin, SH; Sinha, AU; Stein, L; Xie, H; Zhu, N | 1 |
| Batchelor, TT; Louis, DN; Sorensen, AG | 1 |
| Ha, YS; Jeong, P; Kim, IY; Kim, JH; Kim, WJ; Min, BD; Ryu, KH; Song, PH; Yun, SJ | 1 |
| Hamada, J; Hayashi, Y; Kato, Y; Nakada, M; Ooi, A; Sabit, H; Sato, H; Suzuki, S; Watanabe, T; Yoshikawa, A | 1 |
| Guo, SQ; Zhang, YZ | 1 |
| Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J | 1 |
| Bovée, JV; Cleton-Jansen, AM; Hogendoorn, PC; Rozeman, LB; Sciot, R; Taminiau, AH; van Beerendonk, HM | 1 |
| Bibby, MC; Blackburn, A; Lucock, MD; Nicolaou, A | 1 |
| Falk, M; Grigoryev, S; Koristek, Z; Kozubek, M; Kozubek, S; Kroupová, I; Lukásová, E; Ondrej, V | 1 |
| Bhatia, M; Catchings, KL; Glascock, MC; Jones, NG; Kearney, PL; Thompson, PR; Yamada, M; Yuan, L | 1 |
| Braig, M; Dörken, B; Jenuwein, T; Lee, S; Loddenkemper, C; Peters, AH; Rudolph, C; Schlegelberger, B; Schmitt, CA; Stein, H | 1 |
| Motegi, A; Nakajima, T; Nakayama, H; Oyama, T; Sano, T | 1 |
| Arai, M; Kato, Y; Konishi, F; Miki, Y; Nagai, H; Noda, H; Togashi, K; Yoshikawa, H | 1 |
| Carvalho, AL; Henrique, R; Hoque, MO; Jerónimo, C; Lopes, C; Oliveira, J; Pais, I; Ribeiro, FR; Sidransky, D; Teixeira, MR | 1 |
| Agnese, V; Augello, C; Bazan, V; Bruno, L; Calò, V; Cammareri, P; Cascio, S; Corsale, S; Gargano, G; Gerbino, A; Gregorio, V; Gullo, A; Macaluso, M; Morello, V; Passantino, R; Rinaldi, G; Russo, A; Surmacz, E; Tomasino, RM | 1 |
| Esteller, M; Herranz, M | 1 |
| Ford, OH; Liu, Y; Majumder, S; Mohler, JL; Whang, YE | 1 |
| Chen, CY; Chen, YC; Chou, WC; Huang, SY; Ko, BS; Shen, MC; Tang, JL; Tien, HF; Tsay, W; Wang, CH; Wu, SJ; Yao, M; Yeh, YC | 1 |
| Chen, ZG; Hunt, JL; Shin, DM; Zhang, X | 1 |
| Anami, Y; Fukai, S; Iijima, T; Ishiyama, T; Kano, J; Noguchi, M; Okubo, C; Shu, Y; Sun, W; Tanaka, R | 1 |
| Maehara, Y; Yoshino, I | 1 |
| Ackerman, SL; Bernet, A; Coissieux, MM; Gadot, N; Mazelin, L; Mehlen, P; Scoazec, JY | 1 |
| Abraham, JM; Canto, M; Cheng, Y; David, S; Feng, Z; Fredericksen, MB; Greenwald, BD; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Olaru, A; Paun, B; Romero, Y; Sato, F; Schulmann, K; Wang, J; Wang, KK; Wu, TT; Yang, J; Yfantis, HG | 1 |
| Fitzgerald, RC; Gjerset, RA; Huang, Y; Peters, CJ | 1 |
| Ito, N; Montesano, R; Ogawa, K; Shibata, MA; Shirai, T; Takahashi, S; Tsuda, H; Wild, CP | 1 |
| Asou, H; Berenson, J; Koeffler, HP; Munker, R; Nagai, M; Said, JW; Takahara, J; Tasaka, T; Vescio, RA | 1 |
| Hoffmann, GF; Surtees, RA; Wevers, RA | 1 |
| Benítez, J; García, JF; Martínez, JC; Martínez, P; Martinez-Delgado, B; Mateo, MS; Piris, MA; Saez, AI; Sánchez-Beato, M; Sanchez-Verde, L; Villuendas, R | 1 |
| Coulter, J; Feng, AC; Groshen, S; Jones, PA; Knowles, MA; Liang, G; Nichols, PW; Salem, C; Tsai, YC | 1 |
| Di Rocco, A; Simpson, DM | 1 |
22 review(s) available for isomethyleugenol and Disease Exacerbation
| Article | Year |
|---|---|
m
Topics: Disease Progression; Homeostasis; Humans; Methylation; Neoplasms; RNA, Messenger; Transcriptome | 2020 |
Advances into understanding metabolites as signaling molecules in cancer progression.
Topics: Acetylation; Animals; Disease Progression; Glycosylation; Humans; Metabolome; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Signal Transduction | 2020 |
[A Literature Review on the Role of TBX5 in Expression and Progression of Lung Cancer: Current Perspectives].
Topics: Animals; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methylation; T-Box Domain Proteins | 2020 |
N
Topics: Adenosine; Animals; Disease Progression; Humans; Methylation; Methyltransferases; Neoplasms; RNA, Messenger | 2020 |
Targeting Epigenetic Regulators for Endometrial Cancer Therapy: Its Molecular Biology and Potential Clinical Applications.
Topics: Acetylation; Chromatin Immunoprecipitation Sequencing; Disease Progression; DNA Methylation; Endometrial Neoplasms; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Humans; Methylation; Neoplasm Recurrence, Local; RNA, Untranslated | 2021 |
Upregulation of lncRNA NIFK-AS1 in hepatocellular carcinoma by m
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Methylation; Methyltransferases; Molecular Targeted Therapy; Neoplasm Invasiveness; Nuclear Proteins; RNA, Long Noncoding; Sorafenib; Up-Regulation | 2021 |
KDM1A microenvironment, its oncogenic potential, and therapeutic significance.
Topics: Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Histone Demethylases; Histones; Humans; Methylation; Neoplasms; Tumor Microenvironment | 2018 |
The dual role of N6-methyladenosine modification of RNAs is involved in human cancers.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinogenesis; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genetic Therapy; Humans; Methylation; Methyltransferases; Molecular Targeted Therapy; Neoplasms; RNA Editing; RNA, Neoplasm | 2018 |
Treatment of MDS.
Topics: Disease Progression; Erythropoiesis; Hematology; Hematopoietic Stem Cell Transplantation; Humans; Intercellular Signaling Peptides and Proteins; Iron Chelating Agents; Lenalidomide; Methylation; Myelodysplastic Syndromes; Prognosis; Risk; Severity of Illness Index; Translational Research, Biomedical; Transplantation, Homologous | 2019 |
Functions of RNA N6-methyladenosine modification in cancer progression.
Topics: Adenosine; Animals; Disease Progression; Humans; Methylation; Neoplasms; RNA | 2019 |
Functions of RNA N6-methyladenosine modification in cancer progression.
Topics: Adenosine; Disease Progression; Humans; Methylation; Methyltransferases; Neoplasms; RNA; RNA Processing, Post-Transcriptional | 2019 |
The role of microRNAs in diabetic nephropathy.
Topics: Acetylation; Animals; Chromatin; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dogs; Epigenesis, Genetic; Epigenomics; Histones; Humans; Inflammation; Kidney; Lysine; Methylation; Mice; Mice, Transgenic; MicroRNAs; Rats | 2014 |
Characterization of the roles of suppressor of cytokine signaling-3 in prostate cancer development and progression.
Topics: Androgens; Apoptosis; Disease Progression; Humans; Interleukin-6; Male; Methylation; Prostatic Neoplasms; Signal Transduction; Suppressor of Cytokine Signaling Proteins | 2015 |
[Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
Topics: Adenomatous Polyposis Coli Protein; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Progression; DNA Mismatch Repair; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Germ-Line Mutation; Humans; In Situ Hybridization, Fluorescence; Methylation; Phenotype; Precancerous Conditions; Promoter Regions, Genetic | 2016 |
A saga of cancer epigenetics: linking epigenetics to alternative splicing.
Topics: Acetylation; Alternative Splicing; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplasms; RNA Polymerase II; RNA-Binding Proteins; Transcription Elongation, Genetic | 2017 |
Red blood cell transfusion therapy and iron chelation in patients with myelodysplastic syndromes.
Topics: beta-Thalassemia; Deferiprone; Disease Progression; DNA Methylation; Erythrocyte Transfusion; Erythrocytes; Ferritins; Humans; Immunosuppressive Agents; Iron Chelating Agents; Iron Overload; Methylation; Myelodysplastic Syndromes; Pyridones; Risk; Treatment Outcome | 2009 |
Progressive adult primary glioblastoma in the medulla oblongata with an unmethylated MGMT promoter and without an IDH mutation.
Topics: Brain Neoplasms; Chemoradiotherapy; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Fatal Outcome; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Imaging; Medulla Oblongata; Methylation; Middle Aged; Mutation; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2013 |
Overexpression of enhancer of zests homolog 2 in lymphoma.
Topics: Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Histones; Humans; Lymphoma; Methylation; Mutation; Polycomb Repressive Complex 2 | 2012 |
New therapeutic targets in cancer: the epigenetic connection.
Topics: Acetylation; Amino Acid Sequence; Antineoplastic Agents; Clinical Trials as Topic; Disease Progression; DNA Methylation; DNA, Neoplasm; Drug Design; Epigenesis, Genetic; Forecasting; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Methylation; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Protein Conformation; Protein Processing, Post-Translational | 2006 |
Impact of smoking status on the biological behavior of lung cancer.
Topics: Acid Anhydride Hydrolases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Biomarkers; Disease Progression; Health Behavior; Health Status; Humans; Hypoxia-Inducible Factor 1; Japan; Loss of Heterozygosity; Lung Neoplasms; Methylation; Neoplasm Proteins; Nicotiana; Prognosis; Risk Factors; Smoking | 2007 |
Cerebrospinal fluid investigations for neurometabolic disorders.
Topics: Adolescent; Biogenic Monoamines; Biomarkers; Brain Diseases, Metabolic; Child; Child, Preschool; Clinical Protocols; Disease Progression; Female; gamma-Aminobutyric Acid; Gene Expression; Humans; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Methylation | 1998 |
AIDS-associated vacuolar myelopathy.
Topics: Diagnosis, Differential; Disease Progression; HIV Infections; Humans; Male; Methylation; Muscular Atrophy, Spinal; Parasympatholytics; Physical Therapy Modalities; Vitamin B 12 | 1998 |
2 trial(s) available for isomethyleugenol and Disease Exacerbation
| Article | Year |
|---|---|
Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell-Free Nucleic Acids; Disease Progression; Female; Humans; Liquid Biopsy; Methylation | 2023 |
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine.
Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2013 |
140 other study(ies) available for isomethyleugenol and Disease Exacerbation
| Article | Year |
|---|---|
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Topics: 5-Methylcytosine; Aged; Amino Acid Sequence; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Protein Stability; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Stomach Neoplasms; Subcellular Fractions; Sumoylation; Ubiquitins | 2021 |
ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis.
Topics: Animals; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; ets-Domain Protein Elk-4; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Receptor, Notch1; RNA, Long Noncoding; Stomach Neoplasms; Up-Regulation | 2021 |
METTL3-mediated m
Topics: Adenosine; Animals; Autophagy; Autophagy-Related Protein 7; Cartilage, Articular; Cell Line; Cellular Senescence; Chondrocytes; Coculture Techniques; Disease Models, Animal; Disease Progression; Female; GATA4 Transcription Factor; Gene Expression; Humans; Immunoprecipitation; Male; Methylation; Methyltransferases; Mice; Middle Aged; Osteoarthritis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Synoviocytes; Up-Regulation | 2022 |
m
Topics: 3' Untranslated Regions; Adenosine; Aged; Aged, 80 and over; Apoptosis; Aquaporin 1; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Progression; Extracellular Matrix; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; MicroRNAs; Middle Aged; Models, Biological; Osteoarthritis; Phosphate Transport Proteins; RNA Interference; RNA, Long Noncoding | 2021 |
Analysis of the expression patterns and clinical relevance of m
Topics: Biomarkers, Tumor; Computational Biology; Disease Progression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Methylation; Neoplasms; Prognosis; Sequence Analysis, RNA; Tumor Microenvironment | 2022 |
Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis.
Topics: Cell Adhesion Molecules; Cell Line, Tumor; Chemokine CXCL11; Computational Biology; Dendritic Cells; Disease Progression; Drug Resistance, Neoplasm; Female; Ferroptosis; Humans; Intercellular Signaling Peptides and Proteins; Interferon Regulatory Factors; Membrane Glycoproteins; Methylation; N-Acetylgalactosaminyltransferases; Nerve Tissue Proteins; Neutrophils; Nuclear Receptor Subfamily 4, Group A, Member 1; Ovarian Neoplasms; Polycystic Ovary Syndrome; Polypeptide N-acetylgalactosaminyltransferase; Prognosis; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptors, FSH; Receptors, Interleukin; Receptors, Lysophosphatidic Acid; RNA, Messenger; STAT1 Transcription Factor; Transcriptome; Ubiquitin-Protein Ligases | 2022 |
TRAF7-mutated Fibromyxoid Spindle Cell Tumors Are Associated With an Aggressive Clinical Course and Harbor an Undifferentiated Sarcoma Methylation Signature: A Molecular and Clinicopathologic Study of 3 Cases.
Topics: Adult; Aged; Biomarkers, Tumor; Disease Progression; Female; Fibroma; Fibrosarcoma; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Sarcoma; Soft Tissue Neoplasms; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins | 2023 |
Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes.
Topics: Adolescent; Age of Onset; Autoantibodies; Biomarkers; Cell Death; Child; Diabetes Mellitus, Type 1; Disease Progression; Disease Susceptibility; Female; Humans; Insulin; Insulin-Secreting Cells; Male; Methylation; Risk; Young Adult | 2019 |
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Topics: Acetylation; Animals; Azepines; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histocompatibility Antigens; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Snail Family Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta | 2019 |
A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Histones; Humans; Methylation; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Pancreatic Neoplasms; Pyruvic Acid; Retinoblastoma-Binding Protein 2; Signal Transduction; Transcription, Genetic | 2020 |
CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling.
Topics: 3' Untranslated Regions; Animals; ATPases Associated with Diverse Cellular Activities; beta Catenin; Bone Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Disease Progression; DNA Helicases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Lymphoid Enhancer-Binding Factor 1; Methylation; Mice; MicroRNAs; Myosins; Neoplasm Metastasis; Osteosarcoma; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA, Circular; Wnt Signaling Pathway | 2019 |
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Databases, Genetic; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational | 2019 |
miR24-2 Promotes Malignant Progression of Human Liver Cancer Stem Cells by Enhancing Tyrosine Kinase Src Epigenetically.
Topics: Acetylation; Autophagy; Carrier Proteins; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Membrane Proteins; Methylation; MicroRNAs; Nanog Homeobox Protein; Neoplastic Stem Cells; Protein-Arginine N-Methyltransferases; RNA Interference; src-Family Kinases; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2020 |
LncRNA MEG3 inhibits the progression of prostate cancer by facilitating H3K27 trimethylation of EN2 through binding to EZH2.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatin Immunoprecipitation; Disease Progression; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Homeodomain Proteins; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Nerve Tissue Proteins; Prostatic Neoplasms; RNA, Long Noncoding; Up-Regulation; Xenograft Model Antitumor Assays | 2020 |
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3.
Topics: Adenosine; Animals; Cell Line, Tumor; Disease Models, Animal; Disease Progression; GATA3 Transcription Factor; Humans; Liver Neoplasms; Methylation; Mice; Models, Biological; Neoplasm Metastasis; Prognosis; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Antisense; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2019 |
A role for m6A RNA methylation in heart failure development?
Topics: Disease Progression; Heart Failure; Humans; Methylation; RNA; RNA, Messenger | 2020 |
Identification of three m6A-related mRNAs signature and risk score for the prognostication of hepatocellular carcinoma.
Topics: Adenosine; Biomarkers, Tumor; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Methyltransferases; Nomograms; Risk Factors; RNA, Messenger; ROC Curve; Suppressor of Cytokine Signaling Proteins; Transaminases | 2020 |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation.
Topics: Amino Acid Sequence; Arginine; Aurora Kinase B; Breast Neoplasms; Centromere; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Chromosomes, Human; Cytokinesis; Demethylation; Disease Progression; Female; HeLa Cells; Histones; Humans; MCF-7 Cells; Methylation; Mitosis; Nuclear Proteins; Phosphorylation; Protein-Arginine N-Methyltransferases; RNA, Small Interfering | 2020 |
miR24-2 accelerates progression of liver cancer cells by activating Pim1 through tri-methylation of Histone H3 on the ninth lysine.
Topics: Animals; Base Sequence; Cell Line, Tumor; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Liver Neoplasms; Lysine; Male; Methylation; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Models, Biological; Oncogenes; Proto-Oncogene Proteins c-pim-1 | 2020 |
CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasis.
Topics: Acetylation; Animals; Cell Line, Tumor; Chromatin Immunoprecipitation; Colorectal Neoplasms; Disease Progression; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Methylation; Mice; Mice, Nude; Neoplasm Metastasis; Peptide Fragments; Plasmids; Protein Processing, Post-Translational; Sialoglycoproteins; Signal Transduction; Ubiquitin-Protein Ligases | 2020 |
m
Topics: Adenosine; Adult; Aged; Biomarkers, Tumor; Disease Progression; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Middle Aged; Prognosis; Proportional Hazards Models; Protein Interaction Maps; Rectal Neoplasms; RNA; RNA Helicases; RNA-Binding Proteins; Transcriptome | 2020 |
Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression.
Topics: Animals; Cell Proliferation; Chromatin Immunoprecipitation; Chromatography, Liquid; Disease Progression; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Lysine Acetyltransferase 5; Male; Methylation; Mice; Mice, Nude; Nuclear Receptor Subfamily 1, Group F, Member 1; Oncogenes; PC-3 Cells; Prostatic Neoplasms; Protein Binding; Protein Domains; Protein Isoforms; Tandem Mass Spectrometry; Trans-Activators | 2020 |
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromogranins; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; GTP-Binding Protein alpha Subunits, Gs; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; RNA Interference; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2020 |
Methylation‑associated silencing of miR‑638 promotes endometrial carcinoma progression by targeting MEF2C.
Topics: Animals; Apoptosis; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Disease-Free Survival; Down-Regulation; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MEF2 Transcription Factors; Methylation; Mice; Mice, Nude; MicroRNAs; Promoter Regions, Genetic | 2020 |
LNCAROD is stabilized by m6A methylation and promotes cancer progression via forming a ternary complex with HSPA1A and YBX1 in head and neck squamous cell carcinoma.
Topics: Adenosine; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HSP70 Heat-Shock Proteins; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proteasome Endopeptidase Complex; Proteolysis; RNA Stability; RNA, Long Noncoding; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Y-Box-Binding Protein 1 | 2020 |
PRMT5-dependent transcriptional repression of c-Myc target genes promotes gastric cancer progression.
Topics: Adenocarcinoma; Cell Line, Tumor; Disease Progression; Gene Expression; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Stomach Neoplasms | 2020 |
SOX9-activated PXN-AS1 promotes the tumorigenesis of glioblastoma by EZH2-mediated methylation of DKK1.
Topics: Animals; Apoptosis; Base Sequence; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Humans; Intercellular Signaling Peptides and Proteins; Male; Methylation; Mice, Inbred BALB C; Promoter Regions, Genetic; RNA, Long Noncoding; SOX9 Transcription Factor; Wnt Signaling Pathway | 2020 |
m6A RNA methylation regulators correlate with malignant progression and have potential predictive values in clear cell renal cell carcinoma.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Renal Cell; Cohort Studies; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Male; Methylation; Methyltransferases; Middle Aged; Predictive Value of Tests; Prognosis; RNA Processing, Post-Transcriptional; Survival Analysis; Transcriptome | 2020 |
Integrated bioinformatics analysis of expression and gene regulation network of COL12A1 in colorectal cancer.
Topics: Carcinogenesis; Collagen Type XII; Colorectal Neoplasms; Computational Biology; Disease Progression; Extracellular Matrix; Gene Expression Regulation, Neoplastic; Gene Ontology; Gene Regulatory Networks; Humans; Methylation; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction | 2020 |
LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter.
Topics: Carcinogenesis; Cell Line; Class Ib Phosphatidylinositol 3-Kinase; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-akt; Retinoblastoma; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic | 2020 |
Long noncoding RNA ANRIL promotes the malignant progression of cholangiocarcinoma by epigenetically repressing ERRFI1 expression.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cholangiocarcinoma; Disease Models, Animal; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins | 2020 |
Role of SET7/9 in the progression of ischemic renal injury in diabetic and non-diabetic rats.
Topics: Animals; Biomarkers; Cyproheptadine; Diabetes Mellitus, Experimental; Disease Progression; Histone-Lysine N-Methyltransferase; Histones; Hyperglycemia; Inflammation; Ischemia; Kidney; Kidney Tubules, Proximal; Male; Methylation; Rats, Wistar; RNA, Messenger | 2020 |
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Topics: Adenosine; Biomarkers, Tumor; Carcinogenesis; Cluster Analysis; Computational Biology; Datasets as Topic; Disease Progression; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Male; Methylation; Middle Aged; Mouth Neoplasms; Principal Component Analysis; Prognosis; Risk Assessment; RNA Processing, Post-Transcriptional; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck | 2020 |
CD73 acts as a prognostic biomarker and promotes progression and immune escape in pancreatic cancer.
Topics: 5'-Nucleotidase; Aged; Aged, 80 and over; Biomarkers, Tumor; Computational Biology; Disease Progression; Female; Gene Expression Profiling; Gene-Environment Interaction; GPI-Linked Proteins; Humans; Immune Checkpoint Proteins; Lymphocytes, Tumor-Infiltrating; Male; Methylation; Middle Aged; Neoplasm Grading; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Survival Analysis; Transcriptome; Tumor Escape; Tumor Microenvironment | 2020 |
E6 hijacks KDM5C/lnc_000231/miR-497-5p/CCNE1 axis to promote cervical cancer progression.
Topics: Acetylation; Animals; Base Sequence; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Lysine; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Oncogene Proteins; Oncogene Proteins, Viral; Promoter Regions, Genetic; Protein Stability; RNA, Long Noncoding; Tumor Stem Cell Assay; Up-Regulation; Uterine Cervical Neoplasms | 2020 |
The long non-coding RNA SNHG1 promotes bladder cancer progression by interacting with miR-143-3p and EZH2.
Topics: Animals; Antigens, CD; Base Sequence; Cadherins; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Hexokinase; Histones; Humans; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; RNA, Long Noncoding; Transcription, Genetic; Up-Regulation; Urinary Bladder Neoplasms | 2020 |
RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Silencing; Hippo Signaling Pathway; Humans; Liver Neoplasms; Methylation; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; Molecular Mimicry; Prognosis; Protein Biosynthesis; Protein Serine-Threonine Kinases; RNA; RNA, Messenger; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins | 2021 |
Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Enlargement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Gene Expression Profiling; Gene Knockdown Techniques; Heterografts; Humans; Ion Channels; Male; Methylation; Mice; Neoplasm Transplantation; Promoter Regions, Genetic; Prostatic Neoplasms, Castration-Resistant; Protein-Arginine N-Methyltransferases; Receptors, Androgen; Receptors, Histamine H2; Receptors, Histamine H3 | 2020 |
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic | 2020 |
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Topics: Animals; Carcinogenesis; CDX2 Transcription Factor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multivariate Analysis; Nuclear Proteins; Promoter Regions, Genetic; Repressor Proteins; Survival Analysis; Up-Regulation; Wnt Signaling Pathway | 2020 |
Exosome-derived long non-coding RNA ADAMTS9-AS2 suppresses progression of oral submucous fibrosis via AKT signalling pathway.
Topics: Cell Communication; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Exosomes; Gene Expression Profiling; Gene Expression Regulation; Humans; Methylation; MicroRNAs; Oral Submucous Fibrosis; Prognosis; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Signal Transduction | 2021 |
Dysregulation of USP18/FTO/PYCR1 signaling network promotes bladder cancer development and progression.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Carcinogenesis; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; delta-1-Pyrroline-5-Carboxylate Reductase; Disease Progression; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; Methylation; Mice; Neoplasm Staging; Neoplasm Transplantation; Pyrroline Carboxylate Reductases; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Ubiquitin Thiolesterase; Urinary Bladder Neoplasms | 2021 |
Enhancer of zeste homolog 2-mediated paired box 8 methylation promotes gastrointestinal stromal tumor progression through Wnt4 downregulation.
Topics: Animals; Disease Progression; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gastrointestinal Stromal Tumors; Humans; Methylation; Mice; Middle Aged; Wnt4 Protein | 2021 |
RNA N6-methyladenosine: a new player in autophagy-mediated anti-cancer drug resistance.
Topics: Adenosine; Autophagy; Disease Progression; Drug Resistance, Neoplasm; Humans; Methylation; Methyltransferases; Neoplasms; RNA; RNA Processing, Post-Transcriptional | 2021 |
PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling.
Topics: Animals; Arginine; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dextran Sulfate; Disease Progression; DNA Helicases; ErbB Receptors; Histones; Humans; Methylation; Mice; Mice, Inbred C57BL; Models, Biological; Nuclear Proteins; Prognosis; Protein-Arginine N-Methyltransferases; Repressor Proteins; Signal Transduction; Tensins; Transcription Factors; Transcription, Genetic; Up-Regulation | 2021 |
Bioinformatic analyses and experimental validation of the role of m6A RNA methylation regulators in progression and prognosis of adrenocortical carcinoma.
Topics: Adenosine; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Computational Biology; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Immune Checkpoint Inhibitors; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nomograms; RNA; RNA-Binding Proteins; Survival Analysis; Survival Rate; Tumor Microenvironment | 2021 |
Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low-grade glioma.
Topics: Animals; Brain Neoplasms; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Pericytes; Sequence Analysis, RNA; Single-Cell Analysis; Tumor Microenvironment; Tumor Suppressor Proteins; Up-Regulation | 2022 |
Immune infiltration phenotypes of prostate adenocarcinoma and their clinical implications.
Topics: Adenocarcinoma; Cohort Studies; Datasets as Topic; Disease Progression; DNA Copy Number Variations; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Gene Expression Profiling; HSC70 Heat-Shock Proteins; Humans; Immunophenotyping; Lymphocytes, Tumor-Infiltrating; Male; Methylation; Microtubule-Associated Proteins; Middle Aged; Mutation; Mutation Rate; Neoplasm Grading; Neoplasm Proteins; Nomograms; Prognosis; Prostatic Neoplasms; Transcriptome; Tumor Microenvironment | 2021 |
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay | 2021 |
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1.
Topics: Adenosine; Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Male; Metabolome; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neutrophils; Phosphopyruvate Hydratase; Phosphorylation; Principal Component Analysis; Promoter Regions, Genetic; Protein Stability; Receptor, Anaphylatoxin C5a; RNA Splicing Factors; Signal Transduction; Stochastic Processes; Survival Analysis; Tumor Suppressor Proteins; Up-Regulation | 2021 |
M6A methylation of DEGS2, a key ceramide-synthesizing enzyme, is involved in colorectal cancer progression through ceramide synthesis.
Topics: Ceramides; Colorectal Neoplasms; Disease Progression; Humans; Membrane Glycoproteins; Methylation; Nerve Tissue Proteins | 2021 |
Methylation-associated silencing of miR-9-1 promotes nasopharyngeal carcinoma progression and glycolysis via HK2.
Topics: 3' Flanking Region; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Glucose; Glucose-6-Phosphate; Glycolysis; Heterografts; Hexokinase; Humans; In Situ Hybridization, Fluorescence; Lactic Acid; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplastic Stem Cells; RNA, Messenger | 2021 |
Interaction of tau with HNRNPA2B1 and N
Topics: Adenosine; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Case-Control Studies; Cerebral Cortex; Disease Models, Animal; Disease Progression; Female; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Protein Aggregates; Protein Aggregation, Pathological; RNA; RNA Processing, Post-Transcriptional; Severity of Illness Index; tau Proteins | 2021 |
Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dioxygenases; Disease Progression; Histone Demethylases; Histones; Humans; Ikaros Transcription Factor; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Niacinamide; Nuclear Proteins; Phenylurea Compounds; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Signal Transduction; Sorafenib; Transplantation, Heterologous | 2017 |
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Histones; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lipids; Methylation; Mice; Mice, SCID; Molecular Targeted Therapy; Mutation; NADP; Neoplastic Stem Cells; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Messenger | 2017 |
Dedifferentiated Liposarcoma With Epithelioid/Epithelial Features.
Topics: Aged; Biomarkers, Tumor; Biopsy; Cell Dedifferentiation; Claudin-4; Diagnosis, Differential; Disease Progression; Epithelial Cells; Epithelioid Cells; Female; Gene Amplification; Histones; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Keratins; Liposarcoma; Male; Methylation; Middle Aged; Mucin-1; Neoplasm Recurrence, Local; Predictive Value of Tests; Proto-Oncogene Proteins c-mdm2; Time Factors; Treatment Outcome | 2017 |
Study on molecular mechanism of ANOS1 promoting development of colorectal cancer.
Topics: Colorectal Neoplasms; Disease Progression; Extracellular Matrix Proteins; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Protein Interaction Mapping; Survival Analysis; Wnt Signaling Pathway | 2017 |
Long non-coding RNA CCAL promotes hepatocellular carcinoma progression by regulating AP-2α and Wnt/β-catenin pathway.
Topics: Acetylation; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Invasiveness; RNA, Long Noncoding; Transcription Factor AP-2; Wnt Signaling Pathway | 2018 |
Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation.
Topics: Animals; Binding Sites; Disease Progression; Enzyme Inhibitors; Female; HEK293 Cells; Histone Demethylases; Host-Pathogen Interactions; Humans; Influenza A virus; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Models, Biological; Orthomyxoviridae Infections; RNA-Binding Proteins; Tranylcypromine; Vesicular stomatitis Indiana virus; Virus Replication; Zika Virus | 2017 |
Combinatorial strategy of epigenetic and hormonal therapies: A novel promising approach for treating advanced prostate cancer.
Topics: Anticarcinogenic Agents; Azacitidine; beta Catenin; Caspase 3; Cell Proliferation; Cyclin D1; Decitabine; Disease Progression; Epigenesis, Genetic; Estrogen Receptor beta; Hormones; Humans; Hydroxamic Acids; Male; Methylation; Nitriles; Propionates; Prostate; Prostatic Neoplasms; Vascular Endothelial Growth Factor A | 2018 |
Novel long noncoding RNA NMR promotes tumor progression via NSUN2 and BPTF in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Antigens, Nuclear; Biomarkers, Tumor; Chromatin; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Methylation; Methyltransferases; Middle Aged; Nerve Tissue Proteins; Oncogenes; RNA, Long Noncoding; RNA, Messenger; Sequence Analysis, RNA; Tissue Array Analysis; Transcription Factors; Up-Regulation | 2018 |
X chromosome protects against bladder cancer in females via a
Topics: Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, X-Linked; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Histone Demethylases; Methylation; Mice; Mice, Knockout; Mutation; Prognosis; Sex Chromosomes; Sex Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; X Chromosome | 2018 |
Downregulation of HOXA3 in lung adenocarcinoma and its relevant molecular mechanism analysed by RT-qPCR, TCGA and in silico analysis.
Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Computational Biology; Disease Progression; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Lung; Male; Methylation; MicroRNAs; Middle Aged; Real-Time Polymerase Chain Reaction; Young Adult | 2018 |
Restoration of GATA4 expression impedes breast cancer progression by transcriptional repression of ReLA and inhibition of NF-κB signaling.
Topics: Antigens, CD; Apoptosis; Breast Neoplasms; Cadherins; Caspase 8; Cell Cycle; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Female; GATA4 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; MCF-7 Cells; Methylation; Neoplasm Invasiveness; NF-kappa B p50 Subunit; Phosphorylation; Promoter Regions, Genetic; Transcription Factor RelA; Transfection | 2019 |
Reduced miR-125a-5p level in non-small-cell lung cancer is associated with tumour progression.
Topics: A549 Cells; Animals; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; CpG Islands; Disease Progression; Humans; Lung Neoplasms; Methylation; Methyltransferases; Mice; Mice, Nude; MicroRNAs; Middle Aged; Repressor Proteins; Xenograft Model Antitumor Assays | 2018 |
The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer.
Topics: 5-Methylcytosine; Aged; Cell Line, Tumor; Cytidine Deaminase; Deamination; Disease Progression; ErbB Receptors; Female; Humans; Hydrolysis; Lung Neoplasms; Male; Mass Spectrometry; Methylation; Middle Aged; Mutation; NF-kappa B; Polymerase Chain Reaction; Protein-Tyrosine Kinases | 2018 |
Asymmetric dimethylation at histone H3 arginine 2 by PRMT6 in gastric cancer progression.
Topics: Animals; Arginine; Cadherins; Cell Line, Tumor; Disease Progression; Female; Histones; Humans; Male; Methylation; Mice; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Protocadherins; Stomach Neoplasms | 2019 |
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: Data from the E-HOD registry.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cross-Sectional Studies; Disease Progression; Europe; Female; Homocystinuria; Humans; Infant; Infant, Newborn; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Muscle Spasticity; Phenotype; Pregnancy; Psychotic Disorders; Registries; Retrospective Studies; Vitamin B 12; Young Adult | 2019 |
Changes of N6-methyladenosine modulators promote breast cancer progression.
Topics: Adenosine; Adult; Breast; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Methylation; Methyltransferases; Middle Aged; Mutation; Oxidoreductases, N-Demethylating; Prognosis; RNA, Messenger | 2019 |
Six2 promotes non-small cell lung cancer cell stemness via transcriptionally and epigenetically regulating E-cadherin.
Topics: A549 Cells; Animals; Antigens, CD; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cisplatin; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Homeodomain Proteins; Humans; Lung Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Nerve Tissue Proteins; Promoter Regions, Genetic; Transcription, Genetic | 2019 |
A novel combined miRNA and methylation marker panel (miMe) for prediction of prostate cancer outcome after radical prostatectomy.
Topics: Adult; Aged; Biomarkers, Tumor; Cohort Studies; Disease Progression; Humans; Kaplan-Meier Estimate; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Recurrence, Local; Nomograms; Prognosis; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Risk Factors | 2019 |
The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1.
Topics: Adenosine; Adolescent; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Child; Disease Progression; Humans; Lymphoid Enhancer-Binding Factor 1; Methylation; Methyltransferases; Osteosarcoma; RNA Interference; RNA, Messenger; Wnt Signaling Pathway | 2019 |
Long non-coding RNA H19 is responsible for the progression of lung adenocarcinoma by mediating methylation-dependent repression of CDH1 promoter.
Topics: A549 Cells; Adenocarcinoma of Lung; Adult; Aged; Animals; Antigens, CD; Apoptosis; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Promoter Regions, Genetic; RNA, Long Noncoding; RNA, Small Interfering; Young Adult | 2019 |
The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.
Topics: Adult; Biomarkers; Disease Progression; Female; Forkhead Transcription Factors; Humans; Ikaros Transcription Factor; Lupus Erythematosus, Systemic; Male; Methylation; Middle Aged; T-Lymphocytes, Regulatory; Young Adult | 2013 |
CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism.
Topics: Azacitidine; B-Lymphocytes; Cell Proliferation; Cells, Cultured; Chromosomes, Human, Pair 12; Decitabine; Disease Progression; Gene Expression Regulation, Leukemic; Humans; Integrin alpha4; Leukemia, Lymphocytic, Chronic, B-Cell; Methylation; Sequence Analysis, DNA; Signal Transduction; Survival Analysis; Trisomy | 2013 |
Epigenetic modifications induced by Blimp-1 Regulate CD8⁺ T cell memory progression during acute virus infection.
Topics: Amino Acid Sequence; Animals; CD8-Positive T-Lymphocytes; Disease Progression; Epigenesis, Genetic; Histone Deacetylase 2; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunologic Memory; Interleukin-2 Receptor alpha Subunit; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Positive Regulatory Domain I-Binding Factor 1; RNA, Small Interfering; Signal Transduction; Transcription Factors; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 2013 |
The polycomb group protein EZH2 inhibits lung cancer cell growth by repressing the transcription factor Nrf2.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Histones; Humans; Lung Neoplasms; Lysine; Male; Methylation; Middle Aged; NF-E2-Related Factor 2; Polycomb Repressive Complex 2; Survival Analysis | 2014 |
Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.
Topics: Animals; Biosensing Techniques; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Female; Fibrin; Fluorescence Resonance Energy Transfer; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Integrin beta1; Lysine; Melanoma; Melanoma, Experimental; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; RNA, Small Interfering; Skin Neoplasms; SOXB1 Transcription Factors; Time Factors | 2014 |
The role of p300 in the tumor progression of oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Codon; Disease Progression; E1A-Associated p300 Protein; Epithelium; Exons; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Male; Methylation; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Staging; Point Mutation; Promoter Regions, Genetic; Sequence Analysis, RNA; Survival Analysis; Tumor Suppressor Protein p53 | 2015 |
Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
Topics: Astemizole; Binding, Competitive; Catalysis; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Molecular Docking Simulation; Neoplasms; Polycomb Repressive Complex 2; Protein Interaction Mapping; Protein Processing, Post-Translational | 2014 |
Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder.
Topics: Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Dexamethasone; Disease Progression; Epigenesis, Genetic; Female; Glucocorticoids; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Leukocytes, Mononuclear; Male; Methylation; Middle Aged; Pituitary-Adrenal System; Receptors, Glucocorticoid; RNA, Messenger; Saliva; Siblings; Tacrolimus Binding Proteins | 2014 |
Clinical onset and course, response to treatment and outcome in 24 patients with the cblE or cblG remethylation defect complemented by genetic and in vitro enzyme study data.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Age of Onset; Amino Acid Metabolism, Inborn Errors; Cells, Cultured; Child; Child, Preschool; Disease Progression; Female; Ferredoxin-NADP Reductase; Humans; Infant; Infant, Newborn; Male; Methylation; Pregnancy; Retrospective Studies; Treatment Outcome; Vitamin B 12; Young Adult | 2015 |
DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Topics: Alternative Splicing; beta Catenin; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Neoplasm Invasiveness; RNA, Messenger; Up-Regulation | 2015 |
Strong expression of EZH2 and accumulation of trimethylated H3K27 in diffuse large B-cell lymphoma independent of cell of origin and EZH2 codon 641 mutation.
Topics: Cell Line, Tumor; Codon; Computational Biology; Datasets as Topic; Disease Progression; DNA Mutational Analysis; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; Lymphoma, Large B-Cell, Diffuse; Methylation; Mutation; Polycomb Repressive Complex 2 | 2015 |
Alternation of histone and DNA methylation in human atherosclerotic carotid plaques.
Topics: Aged; Blood Cells; Carotid Arteries; Carotid Artery Diseases; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Induction; Female; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Inflammation; Leukocytes; Long Interspersed Nucleotide Elements; Lysine; Macrophages; Male; Methylation; Middle Aged; Mixed Function Oxygenases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neoplasm Proteins; Plaque, Atherosclerotic; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction | 2015 |
[Clinical Implications on ZO-1 Gene Methylation in Myelodysplastic Syndrome Progression].
Topics: Bone Marrow; Disease Progression; DNA Methylation; Humans; Leukemia, Myeloid, Acute; Methylation; Myelodysplastic Syndromes; Polymerase Chain Reaction; Zonula Occludens-1 Protein | 2015 |
Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.
Topics: Calcium-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; HT29 Cells; Humans; Methylation; Neoplasm Metastasis; RNA, Long Noncoding | 2015 |
Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer.
Topics: Antigens, CD; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Progression; Down-Regulation; Endoglin; Gene Silencing; Genes, Tumor Suppressor; Genome-Wide Association Study; Humans; Lung Neoplasms; Methylation; Promoter Regions, Genetic; Protein Array Analysis; Receptors, Cell Surface; Sequence Analysis, DNA | 2015 |
HPV infection and p16 promoter methylation as predictors of ASC-US/LSIL progression.
Topics: Adult; Biopsy, Needle; Cytodiagnosis; Disease Progression; Early Detection of Cancer; Female; Genes, p16; Humans; Immunohistochemistry; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Papillomavirus Infections; Predictive Value of Tests; Promoter Regions, Genetic; Retrospective Studies; Risk Assessment; Squamous Intraepithelial Lesions of the Cervix; Uterine Cervical Dysplasia | 2016 |
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.
Topics: Acetylation; Acute Disease; Child; Child, Preschool; Disease Progression; DNA Copy Number Variations; Female; Gene Regulatory Networks; Histones; Humans; Infant; Leukemia, Myeloid; Leukemia, Myelomonocytic, Juvenile; Male; Methylation; Microscopy, Confocal; Mutation; Phosphatidylinositol 3-Kinases; Polycomb Repressive Complex 2; Protein Subunits; ras Proteins; Sequence Analysis, DNA; Signal Transduction; Survival Analysis; Transcriptome | 2015 |
[Significance of TSLC1 gene methylation and TSLC1 protein expression in the progression of cervical lesions].
Topics: Cell Adhesion Molecule-1; Cell Adhesion Molecules; Disease Progression; DNA Methylation; Female; Humans; Immunoglobulins; Immunohistochemistry; Methylation; Polymerase Chain Reaction; Promoter Regions, Genetic; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2015 |
Upregulated SMYD3 promotes bladder cancer progression by targeting BCLAF1 and activating autophagy.
Topics: Aged; Autophagy; Carcinoma, Transitional Cell; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Histone Code; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Repressor Proteins; RNA Interference; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2016 |
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Topics: Animals; B-Lymphocytes; Carcinogenesis; Cell Line, Tumor; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Code; Humans; Immunoblotting; Lymphoma, B-Cell; Melanocytes; Melanoma; Methylation; Mice; Monomeric GTP-Binding Proteins; Mutation; Neoplasm Transplantation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2016 |
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia.
Topics: Aged; Cell Survival; Cells, Cultured; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Histones; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Methylation; Middle Aged; Mutation; Prognosis; Tumor Suppressor Protein p53 | 2016 |
MINA controls proliferation and tumorigenesis of glioblastoma by epigenetically regulating cyclins and CDKs via H3K9me3 demethylation.
Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Cyclins; Dioxygenases; Disease Progression; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Demethylases; Histones; Humans; Methylation; Mice; Neoplasm Transplantation; Nuclear Proteins; Prognosis; Survival Analysis | 2017 |
MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.
Topics: Acetylation; Cadherins; Cell Line, Tumor; Disease Progression; Down-Regulation; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histone Demethylases; Histones; Humans; Lysine; Methylation; Multiprotein Complexes; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Nucleosomes | 2016 |
Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4.
Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycomics; Humans; Methylation; MicroRNAs; Middle Aged; N-Acetylneuraminic Acid; Neoplasm Metastasis; Polysaccharides; Sialyltransferases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Opposing roles of PIK3CA gene alterations to EZH2 signaling in non-muscle invasive bladder cancer.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histones; Humans; Kaplan-Meier Estimate; Methylation; MicroRNAs; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; Transcription, Genetic; Urinary Bladder Neoplasms | 2017 |
Infundibular protein and RNA microarray analyses from affected and clinically non-affected scalp in male androgenetic alopecia patients.
Topics: Alopecia; Biomarkers; Disease Progression; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation; Hair; Hair Follicle; Humans; Inflammation; Keratins; Male; Methylation; Pilot Projects; RNA; Scalp; Skin | 2017 |
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Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Base Sequence; Brain Neoplasms; Carcinogenesis; Cell Differentiation; Cell Proliferation; Cell Self Renewal; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Meclofenamic Acid; Methylation; Methyltransferases; Mice; Neoplastic Stem Cells; RNA; RNA, Messenger | 2017 |
Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma.
Topics: Azacitidine; Cell Line, Tumor; Claudins; Colorectal Neoplasms; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Gene Expression; Humans; Lymph Nodes; Lymphatic Metastasis; Membrane Proteins; Methylation; Neoplasm Staging; Promoter Regions, Genetic | 2008 |
Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure.
Topics: Arginine; Biomarkers; Chronic Disease; Diastole; Disease Progression; Echocardiography, Doppler; Electrocardiography; Female; Heart Failure, Systolic; Humans; Male; Methylation; Middle Aged; Natriuretic Peptides; Nitric Oxide; Predictive Value of Tests; Prospective Studies; Renal Insufficiency; Tandem Mass Spectrometry; Treatment Outcome; Ventricular Remodeling | 2008 |
Colon cancer: it's CIN or CIMP.
Topics: Chromosomal Instability; Colonic Neoplasms; CpG Islands; Disease Progression; DNA Methylation; Epigenesis, Genetic; Humans; Loss of Heterozygosity; Methylation; Microsatellite Repeats; Models, Biological; Models, Genetic; Neoplasm Metastasis; Phenotype; Prognosis | 2008 |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.
Topics: Acetylation; Azacitidine; Cell Hypoxia; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histocompatibility Antigens; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Methylation; Neoplasm Proteins; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Stomach Neoplasms; Transcription, Genetic | 2009 |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors | 2008 |
Molecular analysis of endometrial tumorigenesis: importance of complex hyperplasia regardless of atypia.
Topics: Adult; Aged; Biomarkers, Tumor; Disease Progression; DNA Mismatch Repair; Endometrial Neoplasms; Female; Humans; Hyperplasia; Methylation; Middle Aged; Oligonucleotide Array Sequence Analysis | 2009 |
Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cytoplasm; Disease Progression; Gene Expression Regulation; GTP-Binding Proteins; Humans; Methylation; Microscopy, Electron; Microscopy, Fluorescence; Protein Biosynthesis; Ribosomes; RNA Processing, Post-Transcriptional; RNA, Ribosomal; RNA, Ribosomal, 28S; Tumor Suppressor Protein p53 | 2009 |
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Methylation; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Survival Rate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Young Adult | 2009 |
Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Chi-Square Distribution; Colitis, Ulcerative; Colorectal Neoplasms; Core Binding Factor Alpha 3 Subunit; Cyclooxygenase 2; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Intestinal Mucosa; Logistic Models; Male; Methylation; Middle Aged; Nerve Tissue Proteins; Polymerase Chain Reaction; Precancerous Conditions; Risk Factors | 2010 |
Role of BMP3 in progression of gastric carcinoma in Chinese people.
Topics: Asian People; Bone Morphogenetic Protein 3; Disease Progression; Humans; Loss of Heterozygosity; Methylation; Microsatellite Instability; Polymorphism, Single-Stranded Conformational; Prognosis; Promoter Regions, Genetic; Stomach Neoplasms | 2010 |
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Assembly and Disassembly; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Genome, Human; Histones; Humans; Methylation; Mice; Mice, Nude; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Polycomb-Group Proteins; Prognosis; Repressor Proteins; RNA Interference; RNA, Untranslated; Survival Rate | 2010 |
Elevated expression of liver X receptor alpha (LXRα) in myocardium of streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Progression; Heart Ventricles; Liver X Receptors; Methylation; Myocardium; Orphan Nuclear Receptors; Rats; RNA, Messenger; Up-Regulation | 2011 |
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Methylation; Mice; Mice, SCID; Neoplastic Stem Cells; Polycomb-Group Proteins; Prostatic Neoplasms; Repressor Proteins; RNA, Messenger; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2011 |
An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression.
Topics: Acetylation; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glutamine; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Repressor Proteins | 2012 |
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
Topics: Adenosine; Animals; Apoptosis; Cells, Cultured; Disease Progression; Enzyme Inhibitors; Graft vs Host Disease; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Isoantigens; Lymphocyte Activation; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Substrate Specificity; T-Lymphocytes; Up-Regulation | 2012 |
An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer.
Topics: Analysis of Variance; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Epigenomics; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Protein Tyrosine Phosphatases; RNA Interference; RNA, Small Interfering; Signal Transduction; Statistics, Nonparametric | 2013 |
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Topics: Animals; Cell Proliferation; Chromatin Immunoprecipitation; Cytoprotection; Disease Progression; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Silencing; Genes, Neoplasm; Genetic Loci; Genome; Histone-Lysine N-Methyltransferase; Histones; Leukemia; Methylation; Mice; Mice, Inbred C57BL; Oncogene Proteins, Fusion; Phenotype; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Precancerous Conditions; Proto-Oncogene Proteins c-myc; Repressor Proteins | 2012 |
Case records of the Massachusetts General Hospital. Case 17-2012. A 54-year-old man with visual-field loss and a mass in the brain.
Topics: Brain; Brain Neoplasms; Chemoradiotherapy; Diagnosis, Differential; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Fatal Outcome; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasms, Second Primary; Recurrence; Tumor Suppressor Proteins; Vision Disorders | 2012 |
RUNX3 methylation in normal surrounding urothelium of patients with non-muscle-invasive bladder cancer: potential role in the prediction of tumor progression.
Topics: Adult; Aged; Aged, 80 and over; Core Binding Factor Alpha 3 Subunit; Disease Progression; Disease-Free Survival; Female; Humans; Male; Methylation; Middle Aged; Prognosis; Urinary Bladder Neoplasms; Urothelium; Young Adult | 2012 |
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors | 2012 |
Molecular analysis of the INK4A/INK4A-ARF gene locus in conventional (central) chondrosarcomas and enchondromas: indication of an important gene for tumour progression.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Chi-Square Distribution; Child; Chondroma; Chondrosarcoma; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Female; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Methylation; Middle Aged; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic | 2004 |
Temporal evaluation of methionine synthase and related metabolites in the MAC15A mouse adenocarcinoma animal model.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Carcinoma; Cell Division; Disease Models, Animal; Disease Progression; Humans; Methionine; Methylation; Mice | 2004 |
Methylation of histones in myeloid leukemias as a potential marker of granulocyte abnormalities.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cell Differentiation; Cell Proliferation; Chromatin; Chromobox Protein Homolog 5; Disease Progression; Granulocytes; Histones; HL-60 Cells; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Methylation; Middle Aged; Tretinoin | 2005 |
Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis.
Topics: Amino Acid Sequence; Ammonia; Arginine; Arthritis, Rheumatoid; Calcium; Catalysis; Disease Progression; Histones; Humans; Hydrogen-Ion Concentration; Hydrolases; Hydrolysis; Kinetics; Methylation; Molecular Sequence Data; Peptides; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Recombinant Proteins; Repressor Proteins; Substrate Specificity | 2005 |
Oncogene-induced senescence as an initial barrier in lymphoma development.
Topics: ADP-Ribosylation Factors; Animals; Apoptosis; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; Chromosomal Instability; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, ras; Heterochromatin; Lymphoma; Methylation; Methyltransferases; Mice; Mice, Transgenic; Precancerous Conditions; Repressor Proteins; Transgenes; Tumor Suppressor Protein p53 | 2005 |
Increasing 14-3-3 sigma expression with declining estrogen receptor alpha and estrogen-responsive finger protein expression defines malignant progression of endometrial carcinoma.
Topics: 14-3-3 Proteins; Adenocarcinoma; Adolescent; Adult; Biomarkers, Tumor; Cell Cycle; Disease Progression; DNA-Binding Proteins; Endometrial Neoplasms; Endometrium; Estrogen Receptor alpha; Exonucleases; Exoribonucleases; Female; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Lymphatic Metastasis; Menstrual Cycle; Methylation; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Polymerase Chain Reaction; Transcription Factors; Tripartite Motif Proteins; Tumor Protein p73; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2005 |
Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Carrier Proteins; Colorectal Neoplasms; Disease Progression; Female; Humans; Male; Methylation; Microsatellite Repeats; Middle Aged; MutL Protein Homolog 1; Neoplasm Invasiveness; Neoplasm Staging; Nuclear Proteins; Promoter Regions, Genetic | 2005 |
Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.
Topics: Aged; Alleles; Cell Transformation, Neoplastic; Clone Cells; Cluster Analysis; Disease Progression; Epigenesis, Genetic; Humans; Male; Methylation; Middle Aged; Neoplasm Proteins; Polymerase Chain Reaction; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms | 2006 |
TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas.
Topics: Adenoma; Base Sequence; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Epigenesis, Genetic; Genotype; Humans; Methylation; Mutation; Proto-Oncogene Proteins p21(ras); Tumor Suppressor Protein p53 | 2006 |
Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability.
Topics: Androgens; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Progression; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Methylation; Prostatic Neoplasms; Protein-Arginine N-Methyltransferases; Receptors, Androgen | 2006 |
Clinical implications of SOCS1 methylation in myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chromosome Aberrations; Disease Progression; Female; Genes, ras; Humans; Karyotyping; Leukemia; Male; Methylation; Middle Aged; Mutation; Myelodysplastic Syndromes; Polymerase Chain Reaction; Prognosis; Risk Factors; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins | 2006 |
Down-regulation of S100A2 in lymph node metastases of head and neck cancer.
Topics: Carcinoma, Squamous Cell; Cell Differentiation; Chemotactic Factors; CpG Islands; Disease Progression; Down-Regulation; Female; Head and Neck Neoplasms; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Methylation; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; S100 Proteins | 2007 |
The ACIN1 gene is hypermethylated in early stage lung adenocarcinoma.
Topics: Adenocarcinoma; Biomarkers, Tumor; Cell Line, Tumor; Disease Progression; DNA, Neoplasm; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methylation; Middle Aged; Neoplasm Staging; Nuclear Proteins; Prognosis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies.
Topics: Animals; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Down-Regulation; Genes, Tumor Suppressor; Humans; Methylation; Mice; Netrin Receptors; Receptors, Cell Surface | 2007 |
Three-tiered risk stratification model to predict progression in Barrett's esophagus using epigenetic and clinical features.
Topics: Barrett Esophagus; Cell Differentiation; Disease Progression; Disease-Free Survival; Endoscopy; Epigenesis, Genetic; Esophageal Neoplasms; Humans; Methylation; Precancerous Conditions; Reproducibility of Results; Risk; Risk Assessment; ROC Curve; Treatment Outcome | 2008 |
Progressive silencing of p14ARF in oesophageal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Base Sequence; Cell Line; Decitabine; Disease Progression; Epithelial Cells; Esophageal Neoplasms; Female; Gene Silencing; Histones; Humans; Male; Methylation; Middle Aged; Molecular Sequence Data; Survival Rate; Tumor Suppressor Protein p14ARF | 2009 |
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
Topics: Administration, Oral; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Deoxyguanosine; Disease Progression; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Injections, Intraperitoneal; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1994 |
Methylation of the p16INK4A gene in multiple myeloma.
Topics: Aged; Blotting, Southern; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Female; Gene Expression; Humans; Male; Methylation; Middle Aged; Multiple Myeloma; Polymerase Chain Reaction; Tumor Cells, Cultured | 1998 |
Loss of p16/INK4A protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumor progression.
Topics: Cells, Cultured; Chromosomes, Human, Pair 9; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; DNA Primers; Flow Cytometry; Humans; Immunoenzyme Techniques; Loss of Heterozygosity; Lymphoma, Non-Hodgkin; Methylation; Microscopy, Confocal; Polymerase Chain Reaction; Proteins; Tumor Suppressor Protein p14ARF | 1998 |
Progressive increases in de novo methylation of CpG islands in bladder cancer.
Topics: Carcinoma, Transitional Cell; CpG Islands; Disease Progression; Exons; Humans; Methylation; Polymerase Chain Reaction; Urinary Bladder Neoplasms; Urothelium | 2000 |