Page last updated: 2024-08-18

isomethyleugenol and Dementia Praecox

isomethyleugenol has been researched along with Dementia Praecox in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-199066 (70.21)18.7374
1990's3 (3.19)18.2507
2000's8 (8.51)29.6817
2010's13 (13.83)24.3611
2020's4 (4.26)2.80

Authors

AuthorsStudies
Handunnetthi, L; Johnson, T; Saatci, D1
Al-Chalabi, N; Chaudhary, Z; De Luca, V; Fischer, C; Gerretsen, P; Graff, A; Qian, J; Remington, G1
Hayashi, T; Kato, Y; Nagai, M; Nakamura, M; Sano, A; Sasaki, N; Tomiyasu, A; Tomiyasu, Y; Ueno, SI; Umehara, H; Yokotsuka-Ishida, S1
Harihar, S; Jung, JY; Lee, PH; Nesbit, N; Silberstein, M; Wallace, R; Zhou, M1
Thomas, EA1
Bator, E; Bilecki, W; Głowacka, U; Latusz, J; Maćkowiak, M1
Pan, W; Wu, C1
Chase, KA; Gavin, DP; Guidotti, A; Sharma, RP1
Crespi, BJ; Hurd, PL; Leach, EL; Prefontaine, G1
Akbarian, S; Shen, E; Shulha, H; Weng, Z1
Cheng, J; Dai, D; Duan, S; Gao, S; Jiang, D; Lv, Y; Zhang, K; Zheng, R; Zhou, K; Zhuang, Q1
Aguilar, DD; Carless, MA; Giuffrida, A; Lodge, DJ; Neary, JL; Perez, SM1
Iwase, S; Vallianatos, CN1
De Luca, V; Dhoot, R; Kennedy, JL; Viggiano, E; Wong, AH1
Chase, K; Gavin, DP; Grayson, DR; Rosen, C; Sharma, RP; Tun, N1
Naumov, AV; Razvodovskiĭ, IuE1
Bellon, A; Beuvon, F; Daumas-Duport, C; Frieling, H; Jay, TM; Kebir, O; Krebs, MO; Le Pen, G; Matricon, J1
Costa, E; Davis, JM; Guidotti, A; Kadriu, B; Pibiri, F; Tueting, P; Veldic, M1
Cascella, N; Colantuoni, C; Eaton, W; Goldman, D; Han, F; Ji, H; Kano, S; Lee, Y; Rapoport, J; Sawa, A; Takayanagi, Y; Wilson, A; Yuan, Q; Zhou, Z1
Huang, TL1
Mattson, MP; Shea, TB1
BRINK, NG; CIRILLO, VJ; GALE, PH; HICHENS, M; KUEHL, FA; MEISINGER, MA; ORMOND, RE1
FRIEDHOFF, AJ; VANWINKLE, E1
Costa, E; Davis, J; Dong, E; Doueiri, MS; Grayson, DR; Guidotti, A; Pinna, G; Rodriguez-Menendez, V; Tremolizzo, L; Tueting, P1
Peedicayil, J; Subbanna, PK1
Agis-Balboa, RC; Costa, E; Davis, JM; Guidotti, A; Kadriu, B; Maloku, E; Veldic, M1
Kakimoto, Y; Kanazawa, A; Kaneko, Z; Sano, I; Tsujio, T1
Van Ree, JM; Verhoeven, WM; Westenberg, HG1
Lewis, ME1
Cuche, H; Loo, H; Sechter, D1
Carney, MW; Reynolds, EH; Toone, BK1
Garver, D; Hirschowitz, J; Hitzemann, R; Mark, C; Panini, A1
Smythies, JR5
Kahn, E1
Antun, FT; Kurkjian, R1
Del Vecchio, M; Maj, M; Zizolfi, S1
Gottfries, CG; Johansson, BV; Regland, B1
Gottfries, CG; Regland, B; Smythies, JR1
Cetkovich-Bakmas, MG; Ciprian-Ollivier, J1
Hurlock, EC1
Davidson, JR; McLeod, MN; White, HL1
Mys'ko, GN1
Birley, JL; Murphy, MP; Murray, RM; Oon, MC; Rodnight, R1
Kety, SS2
Ackenheil, M; Hippius, H; Matussek, N1
Nödl, H1
Ban, TA; Lehmann, HE; Nestoros, JN1
Ban, TA; Lehmann, HE; Luchins, D1
Taylor, WM1
Agnoli, A; Andreoli, VM; Fazio, C1
Dobson, EL; Ismail, L; Pollycove, M; Sargent, T1
Barchas, JD; Ciaranello, RD; Elliott, GR; Erdelyi, E; Sutherland, K; Wyatt, RJ1
Benesh, FC; Carl, GF; Carmichael, SM; Crews, EL; Smythies, JR1
Friedhoff, AJ; Rosengarten, H1
Doust, JW; Huszka, L; Zabek, DH1
Beaton, JM1
Finkelstein, JD; Freeman, JM; Mudd, SH1
Baldessarini, RJ1
Carney, MW1
Braun, G; Braun, U; Bristol, KS; Kusubov, N; Sargent, T1
Frechen, DM; Heleniak, EP1
Alarcon, RD; Bancroft, AJ; Monti, JA; Morere, DA; Smythies, JR; Tolbert, LC; Walter-Ryan, WG1
Garver, D; Hirschowitz, J; Hitzemann, R; Mark, C1
Benjafield, JG; Rutter, LF1
Hartley, R; Smith, JA1
Borghesi, E; Gentili, C1
Ban, TA2
Laduron, P1
Freeman, JM; Mudd, SH1
Axelrod, J; Saavedra, JM; Wyatt, RJ1
Lin, RL; Narasimhachari, N1
Israelstam, DM1
Edelman, GM; Matthysse, S; Puck, TT; Smith, EL1
Price, J1
Ban, TA; Klingner, A; Lehmann, HE1
Cohn, CK; Dunner, DL; Weinshilboum, RM; Wyatt, RJ1
Reznikova, SK; Stoliarov, GV1
Caridroit, M; Duc-Aublet, F; Fontan, M; Miens, C; Testegute, T1
Beck, RA; Goldstein, L; Neiss, ES; Pfeiffer, CC1
Rysánek, K1
Brodsky, L1
Boulton, AA1
Bergen, JR1
Karoum, F; Sandler, M1
Friedhoff, AJ1
Matussek, N1
Finley, NN; Fish, MB; Israelstam, DM; Johnson, A; Motto, J; Pollycove, M; Sargent, T; Winchell, HS1
Thomas, H1

Reviews

24 review(s) available for isomethyleugenol and Dementia Praecox

ArticleYear
Histone Posttranslational Modifications in Schizophrenia.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Amino Acid Sequence; Animals; Brain Chemistry; Disease Models, Animal; Electroconvulsive Therapy; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Humans; Lymphocytes; Methylation; Mice; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Schizophrenia; Ubiquitination

2017
Regulation of histone H3K4 methylation in brain development and disease.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014, Sep-26, Volume: 369, Issue:1652

    Topics: Animals; Autistic Disorder; Brain; Epigenesis, Genetic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Mutation; Nervous System Diseases; Schizophrenia

2014
Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.
    Epigenomics, 2015, Volume: 7, Issue:3

    Topics: Child Development Disorders, Pervasive; Developmental Disabilities; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intellectual Disability; Methylation; Mutation; Schizophrenia

2015
[The role of methylation processes in etiology and pathogenesis of schizophrenia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:8

    Topics: DNA; Genetic Predisposition to Disease; Homocysteine; Humans; Methylation; Receptors, Dopamine; Schizophrenia

2009
Effects of antipsychotics on the BDNF in schizophrenia.
    Current medicinal chemistry, 2013, Volume: 20, Issue:3

    Topics: Acetylation; Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Genotype; Humans; Methylation; Schizophrenia

2013
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
    Trends in neurosciences, 2003, Volume: 26, Issue:3

    Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke

2003
[Biological determinants of schizophrenic psychoses].
    L'Encephale, 1984, Volume: 10, Issue:2

    Topics: Animals; Brain; Catecholamines; Dopamine; Endorphins; Humans; Methylation; Pneumoencephalography; Schizophrenia; Synaptic Transmission; Tomography, X-Ray Computed

1984
Biochemical aspects of schizophrenia.
    Essays in neurochemistry and neuropharmacology, 1980, Volume: 4

    Topics: Amphetamines; Animals; Antipsychotic Agents; Brain; Catecholamines; Dopamine; Humans; Indoles; Mesencephalon; Methionine; Methylation; Monoamine Oxidase; Norepinephrine; Parkinson Disease; Receptors, Dopamine; Schizophrenia

1980
[Biochemistry of schizophrenia and mechanism of action of neuroleptics].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1982, Dec-02, Volume: 58, Issue:44

    Topics: Antipsychotic Agents; Corpus Striatum; Dopamine; Dopamine beta-Hydroxylase; gamma-Aminobutyric Acid; Humans; Hypothalamo-Hypophyseal System; Lypressin; Methylation; Monoamine Oxidase; Neural Pathways; Neurotransmitter Agents; Norepinephrine; Prostaglandins; Receptors, Dopamine; Schizophrenia; Serotonin; Substantia Nigra

1982
Genetics and schizophrenic behavior.
    The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

    Topics: Adoption; Brain; Catecholamines; Diagnosis, Differential; Diseases in Twins; Environment; Female; Genotype; Humans; Methylation; Models, Genetic; Pregnancy; Schizophrenia; Twins, Dizygotic; Twins, Monozygotic

1980
Disturbances of one-carbon metabolism in neuropsychiatric disorders: a review.
    Biological psychiatry, 1997, Jan-15, Volume: 41, Issue:2

    Topics: Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Humans; Methionine; Methionine Adenosyltransferase; Methylation; Neurocognitive Disorders; S-Adenosylmethionine; Schizophrenia

1997
Interferons: potential roles in affect.
    Medical hypotheses, 2001, Volume: 56, Issue:5

    Topics: Affect; Animals; Arginine; Circadian Rhythm; Interferons; Limbic System; Methylation; Mice; Mice, Knockout; Mood Disorders; Schizophrenia; Signal Transduction

2001
Transmethylation hypothesis of schizophrenia: methionine and nicotinic acid.
    International pharmacopsychiatry, 1977, Volume: 12, Issue:4

    Topics: Catechol O-Methyltransferase; Female; Humans; Male; Methionine; Methylation; Methyltransferases; Monoamine Oxidase Inhibitors; Nicotinic Acids; Schizophrenia

1977
A review of nicotinic acid, N-methylated indoleamines and schizophrenia.
    International pharmacopsychiatry, 1978, Volume: 13, Issue:1

    Topics: Bufotenin; Hallucinogens; Humans; Indoles; Methylation; N,N-Dimethyltryptamine; Nicotinic Acids; Schizophrenia

1978
A review of recent studies of the biosynthesis and excretion of hallucinogens formed by methylation of neurotransmitters or related substances.
    Schizophrenia bulletin, 1976, Volume: 2, Issue:1

    Topics: Alcohol Oxidoreductases; Bufotenin; Carbolines; Dimethoxyphenylethylamine; Dopamine; Ethylamines; Folic Acid; Hallucinogens; Humans; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Norepinephrine; S-Adenosylmethionine; Schizophrenia; Serotonin; Tryptamines

1976
Methylation & schizophrenia.
    The Alabama journal of medical sciences, 1975, Volume: 12, Issue:2

    Topics: Amines; Amino Acids; Animals; Behavior, Animal; Catecholamines; Cats; Cystathionine; Cysteine; Dihydroxyphenylalanine; Drug Tolerance; Hallucinogens; Homocysteine; Humans; Indoles; Methionine; Methylation; Mice; Schizophrenia; Serine; Taurine

1975
Biochemical abnormalities associated with schizophrenia.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: Spec No 9

    Topics: Amino Acids, Essential; Brain; Catecholamines; Depression, Chemical; Hallucinogens; Humans; Lysergic Acid Diethylamide; Melatonin; Metabolism; Methylation; Phenethylamines; Schizophrenia; Serotonin; Tryptamines

1975
Neuropharmacology of S-adenosyl methionine.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:3

    Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Dementia; Depressive Disorder; Epilepsy; Folic Acid; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Methionine Adenosyltransferase; Methylation; Nervous System Diseases; Phospholipids; Proteins; Rats; S-Adenosylmethionine; Schizophrenia; Synapses; Synaptic Transmission

1986
Etiology of the stimulant nature of the schizophrenias.
    Recent advances in biological psychiatry, 1966, Volume: 9

    Topics: Alkylation; Amines; Amino Acids; Arousal; Central Nervous System; Electroencephalography; Hallucinogens; Humans; Male; Methylation; Schizophrenia

1966
On-going national collaborative studies in Canada: niacin in the treatment of schizophrenias.
    Psychopharmacology bulletin, 1969, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenochrome; Animals; Canada; Clinical Trials as Topic; Dopamine; Humans; Methylation; Nicotinic Acids; Placebos; Schizophrenia; Serotonin; Stress, Psychological

1969
[Relation of monoamines to mental disorders].
    Activitas nervosa superior, 1970, Volume: 12, Issue:2

    Topics: Amines; Animals; Bipolar Disorder; Catecholamines; Central Nervous System; Depression; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mental Disorders; Methylation; Monoamine Oxidase Inhibitors; Phenethylamines; Psilocybin; Reserpine; Schizophrenia; Serotonin; Tryptamines

1970
A biochemical survey of schizophrenia.
    Canadian Psychiatric Association journal, 1970, Volume: 15, Issue:4

    Topics: Amines; Amphetamine; Antibodies; Antigen-Antibody Reactions; Antimetabolites; Biotransformation; Blood Protein Disorders; Brain; Brain Chemistry; Carbohydrate Metabolism; Ceruloplasmin; Copper; Epinephrine; Humans; Lysergic Acid Diethylamide; Mescaline; Metabolic Diseases; Methylation; Molecular Biology; Phenethylamines; Psychotic Disorders; Research; Schizophrenia; Serotonin

1970
Biochemical research in schizophrenia.
    Nature, 1971, May-07, Volume: 231, Issue:5297

    Topics: Brain; Chromatography, Paper; Hallucinogens; Humans; Methionine; Methylation; Motor Activity; Phenethylamines; Phenylalanine; Schizophrenia; Tryptamines; Tryptophan

1971
Plasma factors, amines and their derivatives in schizophrenia.
    Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:3

    Topics: Amines; Amino Alcohols; Animals; Behavior, Animal; Catecholamines; Central Nervous System; Chromatography, Ion Exchange; Drug Combinations; Drug Stability; Humans; Learning; Lysergic Acid Diethylamide; Mercaptoethanol; Mescaline; Methylation; Phenethylamines; Rats; Schizophrenia; Serum Globulins; Structure-Activity Relationship

1970

Trials

3 trial(s) available for isomethyleugenol and Dementia Praecox

ArticleYear
Negative findings with nicotinic acid in the treatment of schizophrenias.
    International pharmacopsychiatry, 1974, Volume: 9, Issue:3

    Topics: Adrenochrome; Bufotenin; Dimethoxyphenylethylamine; Drug Therapy, Combination; Female; Humans; Male; Methionine; Methylation; Nicotinic Acids; Placebos; Pyridoxine; Pyrroles; Schizophrenia

1974
Nicotinic acid and catechol-O-methyl-transferase activity in schizophrenia.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:1

    Topics: Catechol O-Methyltransferase; Drug Interactions; Hallucinogens; Humans; Methionine; Methylation; Methyltransferases; Monoamine Oxidase Inhibitors; Nicotinic Acids; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Tranylcypromine

1973
On-going national collaborative studies in Canada: niacin in the treatment of schizophrenias.
    Psychopharmacology bulletin, 1969, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenochrome; Animals; Canada; Clinical Trials as Topic; Dopamine; Humans; Methylation; Nicotinic Acids; Placebos; Schizophrenia; Serotonin; Stress, Psychological

1969

Other Studies

68 other study(ies) available for isomethyleugenol and Dementia Praecox

ArticleYear
Maternal immune activation induces methylation changes in schizophrenia genes.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Adult; Brain; Family; Female; Humans; Methylation; Pregnancy; Protein Processing, Post-Translational; Schizophrenia

2022
Dynamic change in genome-wide methylation in response to increased suicidal ideation in schizophrenia spectrum disorders.
    Journal of neural transmission (Vienna, Austria : 1996), 2023, Volume: 130, Issue:10

    Topics: Biomarkers; Humans; Longitudinal Studies; Methylation; Pilot Projects; Psychiatric Status Rating Scales; Schizophrenia; Suicidal Ideation; Suicide, Attempted

2023
Positional cloning and comprehensive mutation analysis identified a novel KDM2B mutation in a Japanese family with minor malformations, intellectual disability, and schizophrenia.
    Journal of human genetics, 2021, Volume: 66, Issue:6

    Topics: Cloning, Molecular; DNA Mutational Analysis; Exome; Exome Sequencing; F-Box Proteins; Female; Genetic Linkage; Genetic Predisposition to Disease; Haplotypes; Histone Demethylases; Histones; Humans; Intellectual Disability; Japan; Jumonji Domain-Containing Histone Demethylases; Male; Marfan Syndrome; Methylation; Mutation; Pedigree; Schizophrenia

2021
Genomewide alteration of histone H3K4 methylation underlies genetic vulnerability to psychopathology.
    Journal of genetics, 2021, Volume: 100

    Topics: Bipolar Disorder; Brain; Depressive Disorder, Major; Genome-Wide Association Study; Histones; Humans; Methylation; Oxidoreductases, N-Demethylating; Protein Processing, Post-Translational; Schizophrenia

2021
Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Male; Methylation; Neurons; Parvalbumins; Prefrontal Cortex; Rats; Rats, Wistar; Schizophrenia; Social Isolation

2019
Integration of methylation QTL and enhancer-target gene maps with schizophrenia GWAS summary results identifies novel genes.
    Bioinformatics (Oxford, England), 2019, 10-01, Volume: 35, Issue:19

    Topics: Genome-Wide Association Study; Humans; Methylation; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Schizophrenia

2019
Histone methylation at H3K9: evidence for a restrictive epigenome in schizophrenia.
    Schizophrenia research, 2013, Volume: 149, Issue:1-3

    Topics: Adult; Cerebral Cortex; Epigenomics; Female; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Humans; Linear Models; Lymphocytes; Lysine; Male; Methylation; Middle Aged; Postmortem Changes; Protein Methyltransferases; Psychiatric Status Rating Scales; RNA, Messenger; Schizophrenia

2013
The imprinted gene LRRTM1 mediates schizotypy and handedness in a nonclinical population.
    Journal of human genetics, 2014, Volume: 59, Issue:6

    Topics: Alleles; CpG Islands; Female; Functional Laterality; Genetic Association Studies; Genetics, Population; Genomic Imprinting; Humans; Male; Membrane Proteins; Methylation; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Psychometrics; Schizophrenia

2014
Significant association between DRD3 gene body methylation and schizophrenia.
    Psychiatry research, 2014, Dec-30, Volume: 220, Issue:3

    Topics: Adult; DNA Methylation; Female; Genetic Association Studies; Humans; Male; Methylation; Receptors, Dopamine D3; Schizophrenia

2014
Schizophrenia-Like Phenotype Inherited by the F2 Generation of a Gestational Disruption Model of Schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:2

    Topics: Animals; Disease Models, Animal; DNA Methylation; Dopaminergic Neurons; Female; Hippocampus; Male; Methylation; Methylazoxymethanol Acetate; Parvalbumins; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Schizophrenia; Transcription Factors; Ventral Tegmental Area

2016
Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosis.
    Journal of psychiatric research, 2009, Volume: 43, Issue:5

    Topics: Adult; Alleles; Bipolar Disorder; Female; Genetic Predisposition to Disease; Humans; Leukocytes; Male; Methylation; Polymerase Chain Reaction; Polymorphism, Genetic; Prefrontal Cortex; Psychotic Disorders; Quantitative Trait, Heritable; Receptor, Serotonin, 5-HT2A; Schizophrenia; Schizophrenic Psychology; Suicide

2009
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures.
    Journal of psychiatry & neuroscience : JPN, 2009, Volume: 34, Issue:3

    Topics: Adult; Age of Onset; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Linear Models; Lymphocytes; Male; Methylation; Schizophrenia

2009
Neuropathological and Reelin deficiencies in the hippocampal formation of rats exposed to MAM; differences and similarities with schizophrenia.
    PloS one, 2010, Apr-22, Volume: 5, Issue:4

    Topics: Animals; Brain Mapping; Cell Adhesion Molecules, Neuronal; Embryonic Development; Extracellular Matrix Proteins; Hippocampus; Humans; Mental Disorders; Methylation; Methylazoxymethanol Acetate; Nerve Tissue Proteins; Neurons; Rats; Reelin Protein; Schizophrenia; Serine Endopeptidases; Teratogens; Thalamus

2010
L-methionine decreases dendritic spine density in mouse frontal cortex.
    Neuroreport, 2010, Jun-02, Volume: 21, Issue:8

    Topics: Animals; Anticonvulsants; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Cell Shape; Dendritic Spines; Disease Models, Animal; Down-Regulation; Drug Interactions; Extracellular Matrix Proteins; Frontal Lobe; GABA Agents; Male; Methionine; Methylation; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Reelin Protein; Schizophrenia; Serine Endopeptidases; Synapses; Valproic Acid

2010
Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia.
    Molecular psychiatry, 2013, Volume: 18, Issue:7

    Topics: Case-Control Studies; Epigenesis, Genetic; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Genome-Wide Association Study; Histones; Humans; Male; Methylation; Olfactory Mucosa; Oxidative Stress; Schizophrenia; Signal Transduction; Tissue Array Analysis

2013
PARA-O-METHYLATION OF DOPAMINE IN SCHIZOPHRENIC AND NORMAL INDIVIDUALS.
    Nature, 1964, Jul-11, Volume: 203

    Topics: Chromatography; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Metabolism; Methylation; Norepinephrine; Phenethylamines; Schizophrenia; Urine

1964
BIOLOGICAL O-METHYLATION AND SCHIZOPHRENIA.
    Psychiatric research reports, 1964, Volume: 19

    Topics: Alkylation; Dopamine; Humans; Metabolism; Methylation; Phenethylamines; Schizophrenia; Transferases

1964
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
    Biological psychiatry, 2005, Mar-01, Volume: 57, Issue:5

    Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid

2005
Revisiting the methylation hypothesis for the psychoses.
    Medical hypotheses, 2007, Volume: 68, Issue:3

    Topics: Bipolar Disorder; DNA Methylation; Humans; Methylation; Psychotic Disorders; Schizophrenia

2007
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder.
    Schizophrenia research, 2007, Volume: 91, Issue:1-3

    Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia; Bipolar Disorder; Caudate Nucleus; Cell Adhesion Molecules, Neuronal; Cohort Studies; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Cytosine Methylases; Epigenesis, Genetic; Extracellular Matrix Proteins; Female; Fluorescence; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; In Situ Hybridization; Male; Methylation; Microscopy, Confocal; Middle Aged; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; Putamen; Reelin Protein; RNA, Messenger; Schizophrenia; Serine Endopeptidases

2007
Metabolic effects of methionine in schizophrenic patients pretreated with a monoamine oxidase inhibitor.
    Nature, 1967, Dec-16, Volume: 216, Issue:5120

    Topics: Adult; Amines; Catechols; Epinephrine; Female; Humans; Isocarboxazid; Methionine; Methylation; Middle Aged; Norepinephrine; Normetanephrine; Schizophrenia

1967
Methylation and mood.
    Lancet (London, England), 1984, Jul-28, Volume: 2, Issue:8396

    Topics: Anemia, Megaloblastic; Brain; Depressive Disorder; Emotions; Folic Acid Deficiency; Humans; Methylation; S-Adenosylmethionine; Schizophrenia; Vitamin B 12; Vitamin B 12 Deficiency

1984
Membranes, methylation and lithium responsive psychoses.
    Nutrition and health, 1984, Volume: 3, Issue:3

    Topics: Blood Platelets; Erythrocyte Membrane; Fatty Acids, Unsaturated; Female; Humans; Lithium; Male; Membrane Lipids; Methylation; Phospholipids; Schizophrenia; Sphingomyelins

1984
The transmethylation and one-carbon cycle hypotheses of schizophrenia.
    Psychological medicine, 1983, Volume: 13, Issue:4

    Topics: Brain; Catecholamines; Folic Acid; Humans; Kinetics; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia

1983
Demethylation of C14 2,3,4-trimethoxyphenylethylamine in schizophrenics before and after L-methionine loading.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Adult; Aged; Female; Humans; Male; Mescaline; Methionine; Methylation; Middle Aged; Schizophrenia

1982
Blood levels of S-adenosylmethionine in unmedicated schizophrenic and depressive patients.
    Neuropsychobiology, 1981, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Female; Humans; Male; Methylation; Middle Aged; S-Adenosylmethionine; Schizophrenia

1981
Homocysteinemia and schizophrenia as a case of methylation deficiency.
    Journal of neural transmission. General section, 1994, Volume: 98, Issue:2

    Topics: Adult; Female; Homocysteine; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Tetrahydrofolates; Vitamin B 12

1994
Altered consciousness states and endogenous psychoses: a common molecular pathway?
    Schizophrenia research, 1997, Dec-19, Volume: 28, Issue:2-3

    Topics: Consciousness; Hallucinations; Hallucinogens; Humans; Methylation; Methyltransferases; Monoamine Oxidase Inhibitors; N,N-Dimethyltryptamine; Phytotherapy; Plants, Toxic; Rubiaceae; Schizophrenia; Serotonin Agents; Shamanism; South America; Visual Perception

1997
Catechol O-methyltransferase in red blood cells of schizophrenic, depressed, and normal human subjects.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 128

    Topics: Adult; Catechol O-Methyltransferase; Depression; Female; Humans; Hydrogen-Ion Concentration; Male; Methylation; Schizophrenia

1976
[Several indices of the methylation process in schizophrenic patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1977, Volume: 77, Issue:7

    Topics: Adult; Antipsychotic Agents; Automatism; Catechol O-Methyltransferase; Depression; Female; Hallucinations; Humans; Isoproterenol; Male; Methylation; Middle Aged; Niacinamide; Schizophrenia; Schizophrenia, Catatonic; Schizophrenia, Paranoid; Syndrome

1977
Factors affecting the urinary excretion of endogenously formed dimethyltryptamine in normal human subjects.
    Psychopharmacology, 1977, Oct-20, Volume: 54, Issue:2

    Topics: Adult; Aged; Ammonium Chloride; Animals; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Male; Methionine; Methylation; Middle Aged; N,N-Dimethyltryptamine; Physical Exertion; Rabbits; Schizophrenia; Tryptamines

1977
Biochemistry of the central nervous system and behavior.
    Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18

    Topics: Affective Symptoms; Animals; Behavior; Brain; Humans; Methylation; Neurotransmitter Agents; Schizophrenia

1978
[Findings of biochemical research on schizophrenia (author's transl)].
    Der Nervenarzt, 1978, Volume: 49, Issue:11

    Topics: 5-Methoxytryptamine; Antipsychotic Agents; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Lysergic Acid Diethylamide; Methylation; Models, Psychological; Monoamine Oxidase; Norepinephrine; Psychoses, Substance-Induced; Receptors, Dopamine; Research; Schizophrenia; Serotonin

1978
Biochemistry and the schizophrenias.
    Southern medical journal, 1979, Volume: 72, Issue:10

    Topics: Dopamine; Humans; Methionine; Methylation; N,N-Dimethyltryptamine; Neurotransmitter Agents; Schizophrenia

1979
Recent progress in schizophrenia research.
    Lancet (London, England), 1976, Jul-17, Volume: 2, Issue:7977

    Topics: Adolescent; Animals; Brain; Diet; Dopamine; Female; Humans; Methylation; Rats; Schizophrenia; Serotonin; Tryptophan; Tyrosine

1976
[Genetic and biologic aspects of schizophrenias].
    Fortschritte der Medizin, 1979, Jan-04, Volume: 97, Issue:1

    Topics: Child; Dopamine; Environment; Humans; Methylation; Norepinephrine; Schizophrenia; Synaptic Transmission

1979
Schizophrenia, rheumatoid arthritis and trytophan metabolism.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:6

    Topics: Arthritis, Rheumatoid; Female; Humans; Male; Methionine; Methylation; Monoamine Oxidase; Protein Binding; Schizophrenia; Serotonin; Synovial Fluid; Tryptamines; Tryptophan

1978
Transmethylations and the central nervous system: introduction.
    Monographien aus dem Gesamtgebiete der Psychiatrie, 1978, Volume: 18

    Topics: Brain; Humans; Methylation; S-Adenosylmethionine; Schizophrenia

1978
Altered metabolism of the methionine methyl group in the leukocytes of patients with schizophrenia.
    Biological psychiatry, 1978, Volume: 13, Issue:6

    Topics: Adult; Carbon Dioxide; Female; Humans; Leukocytes; Male; Methionine; Methylation; Middle Aged; Schizophrenia

1978
N5,10-methylenetetrahydrofolate reductase activity in autopsied brain parts of chronic schizophrenics and controls and in vitro tryptoline formation.
    Biological psychiatry, 1978, Volume: 13, Issue:6

    Topics: Animals; Brain; Carbolines; Chronic Disease; Humans; Indoles; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Oxidoreductases; Rats; Schizophrenia

1978
Four enzymes of one-carbon metabolism in blood cells of schizophrenics.
    Biological psychiatry, 1978, Volume: 13, Issue:6

    Topics: Alcohol Oxidoreductases; Blood Platelets; Erythrocytes; Female; Glycine Hydroxymethyltransferase; Humans; Male; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Schizophrenia; Tetrahydrofolates

1978
Urinary excretion of n,n-dimethylated tryptamines in chronic schizophrenia. A review of the present status of the hypothesis.
    Canadian Psychiatric Association journal, 1976, Volume: 21, Issue:8

    Topics: 5-Methoxytryptamine; Adult; Bufotenin; Chronic Disease; Epinephrine; Female; Humans; Hydroxyindoleacetic Acid; Methylation; Middle Aged; N,N-Dimethyltryptamine; Norepinephrine; Phenelzine; Schizophrenia; Serotonin; Tryptamines; Tryptophan

1976
Folate-responsive homocystinuria and "schizophrenia". A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity.
    The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10

    Topics: Adolescent; Alcohol Oxidoreductases; Diagnosis, Differential; Female; Folic Acid; Homocysteine; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Schizophrenia; Tetrahydrofolates; Vitamin B 12

1975
Editorial: Metabolic hypotheses in schizophrenia.
    The New England journal of medicine, 1975, Mar-06, Volume: 292, Issue:10

    Topics: Folic Acid; Homocystine; Homocystinuria; Humans; Methionine; Methylation; Psychotic Disorders; Schizophrenia

1975
Cerebral and peripheral demethylation of psychotomimetics measured by expired 14CO2.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1989, Volume: 16, Issue:1

    Topics: Amphetamines; Animals; Biotransformation; Brain; Carbon Dioxide; Carbon Radioisotopes; Hallucinogens; Humans; Injections; Injections, Intravenous; Methoxydimethyltryptamines; Methylation; Molecular Structure; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Schizophrenia; Structure-Activity Relationship; Tryptamines

1989
Histamine methylation in schizophrenia.
    Medical hypotheses, 1989, Volume: 30, Issue:3

    Topics: Histamine; Humans; Methylation; Schizophrenia

1989
Medication effects on one-carbon metabolism in schizophrenia, mania, and major depression.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Erythrocytes; Humans; Lithium; Methionine Adenosyltransferase; Methylation; Phosphatidylcholines; Schizophrenia; Transferases

1986
Characteristics of phospholipid methylation in human erythrocyte ghosts: relationship(s) to the psychoses and affective disorders.
    Biological psychiatry, 1985, Volume: 20, Issue:4

    Topics: Adult; Bipolar Disorder; Erythrocyte Membrane; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Lithium; Magnesium; Male; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; Schizophrenia; Sphingomyelins

1985
Significance of metabolic disorders in schizophrenia.
    Lancet (London, England), 1973, Apr-07, Volume: 1, Issue:7806

    Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Metabolism, Inborn Errors; Dopamine; Female; Humans; Male; Methylation; Schizophrenia; Tyrosine

1973
Abnormal O-methylated dopamine metabolites: the endogenous toxins of schizophrenia or parkinsonism?
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:5

    Topics: Animals; Behavior, Animal; Hallucinogens; Humans; Methylation; Parkinson Disease; Phenethylamines; Schizophrenia; Toxins, Biological

1973
Toward hypotheses for a biochemical component in the vulnerability to schizophrenia.
    Seminars in psychiatry, 1972, Volume: 4, Issue:3

    Topics: Amphetamine; Antipsychotic Agents; Brain; Butyrophenones; Disease Susceptibility; Dopamine; Dopamine beta-Hydroxylase; Hallucinations; Hallucinogens; Humans; Methionine; Methylation; Norepinephrine; Phenothiazines; Psychoses, Substance-Induced; Receptors, Drug; Schizophrenia; Structure-Activity Relationship

1972
[Remarks on the level of transmethylases in schizophrenic patients. In vitro assays].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Nov-30, Volume: 43, Issue:22

    Topics: Betaine; Humans; In Vitro Techniques; Methylation; Niacinamide; Schizophrenia

1967
A new hypothesis on the origin of schizophrenia.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Brain; Folic Acid; Humans; Liposomes; Methylation; Schizophrenia; Tetrahydrofolates

1974
N-5,10-methylenetetrahydrofolate reductase deficiency and schizophrenia: a working hypothesis.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Dopamine; Female; Fibroblasts; Folic Acid; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Oxidoreductases; Schizophrenia; Tetrahydrofolates

1974
A dimethyltryptamine-forming enzyme in human blood.
    The American journal of psychiatry, 1973, Volume: 130, Issue:7

    Topics: Adolescent; Adult; Alcoholism; Blood Platelets; Blood Proteins; Carbon Isotopes; Depression; Erythrocytes; Female; Hallucinogens; Humans; Male; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Psychotic Disorders; Renal Dialysis; S-Adenosylmethionine; Schizophrenia; Tryptamines

1973
A possible mechanism for the antischizophrenic action of chlorpromazine: inhibition of the formation of dimethyltryptamine by chlorpromazine metabolites.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:2

    Topics: Animals; Carbon Radioisotopes; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Hallucinogens; Humans; Imipramine; In Vitro Techniques; Indoles; Lung; Mass Spectrometry; Methylation; Methyltransferases; N,N-Dimethyltryptamine; Rabbits; S-Adenosylmethionine; Schizophrenia; Serotonin; Solvents; Tetrahydrofolates; Time Factors; Tryptamines

1974
From medical physicist to psychopharmacologist: a neo-renaissance interdisciplinary evolution of.
    Perspectives in biology and medicine, 1972,Spring, Volume: 15, Issue:3

    Topics: Dihydroxyphenylalanine; Disulfiram; Electroconvulsive Therapy; Enzyme Induction; History, 20th Century; Humans; Lysergic Acid Diethylamide; Memory; Methylation; Psychopharmacology; Psychotic Disorders; Schizophrenia; Stress, Physiological; Tryptamines; United States; Wit and Humor as Topic

1972
Prospects for research on schizophrenia. VI. Biochemical hypotheses and new techniques.
    Neurosciences Research Program bulletin, 1972, Volume: 10, Issue:4

    Topics: Brain; Catecholamines; Cells, Cultured; Culture Techniques; Dopamine; Endocrine System Diseases; Humans; Metabolic Diseases; Methylation; Research; Schizophrenia

1972
Methylation in schizophrenics: a pharmacogenetic study.
    Journal of psychiatric research, 1972, Volume: 9, Issue:4

    Topics: Benzoates; Creatinine; Diet; Female; Humans; Hydrogen-Ion Concentration; Male; Methylation; Pharmacogenetics; Schizophrenia

1972
The activity of dopamine-beta-hydroxylase and methionine-activating enzyme in blood of schizophrenic patients.
    Biological psychiatry, 1973, Volume: 6, Issue:3

    Topics: Adenosine Triphosphate; Catecholamines; Chronic Disease; Dopamine beta-Hydroxylase; Erythrocytes; Humans; Hydroxylation; Incubators; Methionine; Methylation; S-Adenosylmethionine; Schizophrenia; Transferases; Tritium

1973
[The methylating activity of the blood in schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:1

    Topics: Alcoholism; Bipolar Disorder; Epilepsy; Humans; Methylation; Psychoses, Alcoholic; Schizophrenia

1973
[Biochemical study of a schizophreniac].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1973, Volume: 18, Issue:10

    Topics: Adult; Cysteine; Humans; Male; Methylation; Monoamine Oxidase Inhibitors; Phenylalanine; Schizophrenia; Transferases; Tryptophan

1973
High-resolution gas chromatographic analysis of phenolic acids and alcohols using capillary columns.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 32, Issue:3

    Topics: Benzoates; Capillary Action; Chemistry, Clinical; Chromatography, Gas; Homogentisic Acid; Humans; Mandelic Acids; Methylation; Phenylacetates; Propionates; Schizophrenia; Silicon

1971
[Current status of studies on dimethoxyphenylethylamine in schizophrenia].
    Vestnik Akademii meditsinskikh nauk SSSR, 1969, Volume: 24, Issue:4

    Topics: Humans; Methylation; Phenethylamines; Schizophrenia

1969
[The skeleton structure of a hallucinogenic molecule].
    Vestnik Akademii meditsinskikh nauk SSSR, 1969, Volume: 24, Issue:4

    Topics: Hallucinogens; Humans; Methylation; Norepinephrine; Phenethylamines; Schizophrenia

1969
[Molecular-biologic causes in psychiatry].
    Munchener medizinische Wochenschrift (1950), 1969, Dec-12, Volume: 111, Issue:50

    Topics: Antidepressive Agents; Brain; Deficiency Diseases; Depression; Humans; Methylation; Molecular Biology; Norepinephrine; Reserpine; Schizophrenia

1969
Abnormal methionine metabolism in schizophrenic and depressive states: a preliminary report.
    Journal of psychiatric research, 1970, Volume: 7, Issue:3

    Topics: Acute Disease; Carbon Dioxide; Carbon Isotopes; Depression; Humans; Methionine; Methylation; Schizophrenia; Statistics as Topic

1970
[On methylation processes in metabolism].
    Die Medizinische Welt, 1969, Feb-22, Volume: 8

    Topics: Biochemical Phenomena; Biochemistry; Choline; Dietary Fats; Epinephrine; Fatty Liver; Humans; Mescaline; Metabolism; Methionine; Methylation; Norepinephrine; Phenethylamines; Phosphatidylcholines; Schizophrenia

1969