Page last updated: 2024-08-18

isomethyleugenol and Cell Transformation, Neoplastic

isomethyleugenol has been researched along with Cell Transformation, Neoplastic in 344 studies

Research

Studies (344)

TimeframeStudies, this research(%)All Research%
pre-1990112 (32.56)18.7374
1990's46 (13.37)18.2507
2000's49 (14.24)29.6817
2010's106 (30.81)24.3611
2020's31 (9.01)2.80

Authors

AuthorsStudies
Hu, W; Jiang, J; Li, J; Liu, G; Liu, K; Liu, Q; Lou, Y; Yang, L; Yang, M; Zhang, Y; Zhao, P; Zhao, Z1
Chen, Y; Qi, Y; Wang, B; Wang, D; Wang, Q; Xiong, F1
Fan, X; Pan, H; Wang, H; Yang, F; Zhang, H; Zhang, X1
Chen, W; He, Z; Hong, Z; Ji, K; Li, S; Liu, M; Peng, X; Song, M; Xu, Y; Yang, C; Yu, J; Zhang, Q; Zhou, J; Zhu, Q; Zuo, Q1
Feng, Y; He, A; Jia, Y; Jin, H; Kong, G; Li, Z; Liu, R; Shen, Y; Shi, L; Yang, D; Yang, Y; Yu, X; Zhang, L; Zhang, P; Zhang, X1
Aziz, N; Cho, JY; Hur, H; Kang, JS; Kim, E; Kim, HG; Kim, JH; Kim, KH; Lee, J; Manavalan, B; Parameswaran, N; Rahmawati, L; Yoo, BC1
Hong, D; Hu, F; Huang, C; Huang, H; Jin, H; Jin, R; Li, H; Liu, D; Ren, G; Sun, W; Wu, S; Zhang, X; Zhao, L1
Gu, R; Janknecht, R; Kim, TD; Oh, S; Shin, S; Song, H; Sui, Y1
Deng, X; He, YH; Hu, GS; Huang, HH; Huang, Y; Li, MY; Li, WJ; Lin, YA; Liu, W; Xie, BL; Yang, JJ; Zhang, BD; Zou, YQ1
Chen, K; Chen, Z; Huang, C; Xiang, W; Zeng, J; Zhang, Y1
Devi, NS; Kaluz, S; Olson, JJ; Van Meir, EG; Yu, B; Zhang, H; Zhang, Z; Zhu, D1
Chen, J; Cui, J; Fallon, MB; Gao, Y; Guha, S; Quan, M; Xie, D; Xie, K1
Chen, J; Chen, S; Fan, S; Fang, X; Fang, Y; Liu, G; Ma, J; Shen, P; Shen, S; Wang, S; Wu, H; Wu, Y; Xie, Z; Yang, Y1
Chai, P; Fan, X; Ge, S; Jia, R; Sun, B; Wang, S; Xu, Y; Yang, Y; Yang, YG1
Bai, R; Chen, Z; Gao, X; Han, B; Liu, K; Sheng, J; Wei, S; Xiang, J; Xu, Z; Yan, S1
Abe, S; Kadonosono, T; Matsumura, M; Nakamura, H; Sato, S; Ueda, H; Ueno, T1
Chen, Q; Ji, C; Lin, K; Miao, L; Xu, A; Yang, J; Yang, L; Yu, Y; Zhang, X1
Chen, C; Geng, W; Guo, H; Wang, Q; Wang, S; Wang, Z; Xu, K1
Feng, W; Gao, J; Hou, Y; Huang, W; Liu, W; Qiu, R; Su, D; Teng, X; Wang, Y; Yang, Y; Yi, X; Yu, H; Zhang, K; Zhang, T1
Chen, D; Chen, J; Cheng, M; Gao, F; He, Q; Huang, Z; Li, Q; Liang, J; Liu, L; Peng, L; Ren, H; Wang, A; Wu, Y; Zhao, L1
Demers, I; Henfling, MER; Hoogduin, KJ; Hopman, ANH; Looijenga, LHJ; Moshi, JM; Ramaekers, FCS; Stoop, H; Ummelen, M; van Engeland, M; Wouters, KAD1
Du, W; Duan, R; Guo, W1
Guo, Y; He, X; Stha, A; Sun, Y; Wang, M; Wu, X; Xu, C; Zhang, W1
Dong, W; Li, Q; Liu, P; Ma, Z; Zuo, Y1
Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W1
He, Z; Li, Z; Zhang, C; Zhou, S; Zhu, Y1
Huang, ZM; Ji, ZG; Wang, H1
Dere, R; Young, NL1
Chai, P; Gu, X; He, F; Jia, R; Shi, H; Wang, S; Xu, X; Yang, J; Yu, J; Zhuang, A1
Liu, F; Su, X1
Chen, E; Li, M; Liu, J; Wu, J; Xu, E; Yang, Q; Zhang, C; Zhou, J1
He, Y; Hu, Y; Liu, W; Su, Y; Xiao, B1
Barbosa, K; Bohlander, SK; Cox, KL; Deshpande, A; Deshpande, AJ; Khanal, S; Klein, BJ; Kutateladze, TG; Poirier, MG; Shi, X; Sinha, A; Tong, Q; Wen, H; Xuan, F; Zandian, M; Zhang, P; Zhang, Y1
Arai, T; Chijimatsu, R; Doki, Y; Eguchi, H; Hirotsu, T; Ishii, H; Kitagawa, T; Ofusa, K; Takeda, Y; Vecchione, A; Yabumoto, M1
Bai, J; Chen, H; He, A; Wang, X1
Dixit, D; Rich, JN; Xie, Q; Zhao, JC1
Kong, M; Lowman, XH; Tran, TQ1
Dohmae, N; Hamamoto, R; Matsuo, Y; Nakamura, Y; Suzuki, T; Tsurita, G; Watanabe, T; Yoshioka, Y1
Bartenhagen, C; Bäumer, N; Berdel, WE; Cui, C; Dugas, M; Farouq, D; Garcia-Cuellar, MP; Gerloff, D; Göllner, S; Hébert, J; Hüttelmaier, S; Klein, HU; Köhn, M; Liu, Y; Maciejewski, JP; Misiak, D; Müller-Tidow, C; Oellerich, T; Pabst, C; Pauli, C; Przychodzen, B; Regev, A; Rohde, C; Sauvageau, G; Schwartz, S; Seliger, B; Serve, H; Slany, R; Taketo, MM; Zhou, F1
Adams, DJ; Basheer, F; Bashford-Rogers, R; Burrows, N; Chan, WI; Clipson, A; Du, MQ; Erdem, A; Fitzgibbon, J; Foerster, S; Gallipoli, P; Giotopoulos, G; Hodson, D; Horton, SJ; Huntly, BJP; Laurenti, E; Maxwell, P; Okosun, J; Osaki, H; Petrunkina Harrison, A; Rashid, M; Sasca, D; Sheppard, O; Smith, KG; Sustic, T; Sybirna, A; Vohra, S; Wright, P; Yiangou, L; Yun, H; Zhao, W1
Anandi, L; Ashiq, KA; Bodakuntla, S; Chakravarty, V; Lahiri, M1
Allahverdi, A; Chung, HH; Cukuroglu, E; Geifman-Shochat, S; Göke, J; Lin, VCL; Madhusudhan, MS; Nordenskiöld, L; Su, IH; Tan, KP; Venkatesan, N; Wong, JF; Yau, YH1
Liu, Y; Tu, W; Xie, C; Zhou, X1
Kaneko, S; Li, X1
Chen, J; Chen, L; Fang, H; Fang, L; Ge, X; Han, D; Jiao, C; Jin, J; Jin, X; Li, C; Li, Y; Liao, G; Liao, L; Liu, M; Liu, Z; Peng, X; Qin, HL; Teng, H; Wang, P; Wang, X; Wang, Y; Wei, Q; Weng, L; Yang, Y; Zhang, S; Zhao, B; Zhou, D; Zhou, J1
He, C; Li, Z; Liu, H; Luan, S; Luo, J1
Banerjee, HN; Kahan, W; Kumar, V; Verma, M1
Armstrong, SA; Cai, S; Dou, Y; Dressler, GR; Ge, K; Hess, JL; Jang, Y; Koche, R; Levine, RL; Mao, F; Miao, H; Phuc Khoa, LT; Sun, Y; Witkin, M; Xu, J; Zhou, B; Zou, Z1
Kidder, BL; Xhabija, B1
Furuya, K; Ikura, M; Ikura, T1
Bassik, MC; Caporicci, M; Carlson, SM; Elias, JE; Francis, JW; Fuentes, ME; Gozani, O; Hausmann, S; Hulea, L; Kim, MP; Li, A; Liu, S; Lofgren, SM; Lu, J; Maitra, A; Mazur, PK; Nguyen, ND; Pillai, R; Porco, JA; Song, J; Tandoc, K; Topisirovic, I; Van Rechem, C; Wang, H; Wistuba, II1
Allis, CD; Bagert, JD; Feng, L; Gao, J; Kundra, R; Lemiesz, AE; Muir, TW; Nacev, BA; Schultz, N; Soshnev, AA1
Chen, J; Lin, N; Lu, Y; Xu, M; Xu, R; Yao, Z; Yuan, L; Zhou, S; Zou, X1
Beck, DB; Dooley, SJ; Fondevila, D; Kane-Goldsmith, N; Krüger, M; Marazuela-Duque, A; Martínez-Redondo, P; Muñoz, P; Rabanal, RM; Serrano, L; Tischfield, JA; Tong, Q; Vaquero, A; Vazquez, BN; Voigt, P1
Biller, SA; Brennan, CW; Campos, C; Chan, TA; Chen, Y; Clark, O; Graeber, TG; Grommes, C; Kernytsky, A; Komisopoulou, E; Kunii, K; Liu, W; Mellinghoff, IK; Miller, A; Oldrini, B; Palaskas, N; Pedraza, A; Popovici-Muller, J; Rohle, D; Rosenblum, MK; Schalm, S; Silverman, L; Su, SM; Tsoi, J; Turcan, S; Wang, F; Yang, H; Yen, KE1
Cho, EJ; Choi, A; Han, JW; Jang, H; Jo, CH; Kim, ST; Kim, YN; Lee, HY; Lee, J; Lim, J; Park, J; Song, TY; Song, Y; Yang, JH; Yang, YJ; Youn, HD1
Davie, JR; Guppy, BJ; McManus, KJ; Sawchuk, L; Thompson, LL1
Behrens, A; Chakraborty, A; Davies, CC; Diefenbacher, ME; Skehel, M1
Abdel-Wahab, O; Béguelin, W; Bunting, KL; Cerchietti, L; Chung, YR; Creasy, CL; Elemento, O; Ezponda, T; Gascoyne, RD; Jiang, Y; Kelleher, N; Kruger, RG; Levine, RL; Licht, JD; Liu, Y; Martinez-Garcia, E; McCabe, MT; McHugh, CF; Melnick, AM; Ott, HM; Popovic, R; Rosen, M; Scott, DW; Shaknovich, R; Shen, H; Teater, M; Van Aller, GS; Verma, SK; Wang, L; Wong, KK; Yang, SN; Zhang, H; Zheng, Y1
Chang, N; Joo, KM; Kim, E; Kim, H; Kim, M; Lee, C; Lee, J; Nakano, I; Nam, DH; Oh, YT; Rheey, J; Rich, JN; Shin, J; Shin, Y; Woo, DH1
Singh, KP; Treas, J; Tyagi, T1
Barnett, GH; Barnholtz-Sloan, JS; Capella, D; Chen, Y; Chiocca, EA; Cohen, ML; Devine, K; Elder, JB; Guan, X; Kerstetter, A; McPherson, C; Ostrom, QT; Selman, W; Sloan, AE; Vengoechea, J; Warnick, RE; Wolinsky, Y1
Albaret, MA; Belin, S; Bourdon, JC; Bouvet, P; Catez, F; Cong, R; Diaz, JJ; Ghayad, SE; Hacot, S; Jordan, L; Marcel, V; Mertani, HC; Morel, AP; Prats, AC; Puisieux, A; Saurin, JC; Solano-Gonzàlez, E; Tafer, Y; Therizols, G; Thompson, A; Vendrell, JA1
Kojima, C; Tokar, EJ; Waalkes, MP1
Hendzel, MJ; Young, LC1
Chen, D; Hu, L; Lin, G; Liu, L; Lu, G; Ouyang, Q; Sun, Y; Xie, P; Yuan, D; Zeng, S1
Bryll, A; Dyson, NJ; Manning, AL; Nicolay, B; Yazinski, SA; Zou, L1
Käser-Pébernard, S; Müller, F; Wicky, C1
Aparicio, SA; Berg, T; Bilenky, M; Chang, H; Cheng, SW; Gascoyne, RD; Hirst, M; Humphries, RK; Lai, CK; Lai, D; Lee, S; Lim, E; Marra, MA; Morin, GB; Morin, RD; Mungall, AJ; Oellerich, T; Rosten, P; Salmi, A; Schoeler, N; Serve, H; Thoene, S; Umlandt, P; Wee, T; Yap, D; Yue, L1
Barbash, O; Butte, AJ; Dhanak, D; Garcia, BA; Gozani, O; Huddleston, M; Jansen, PW; Khatri, P; Kruger, RG; Liu, S; Mazur, PK; Reynoird, N; Sage, J; Tummino, PJ; Van Aller, GS; Vermeulen, M; Wilkinson, AW1
Hamamoto, R; Nakakido, M; Nakamura, Y; Toyokawa, G; Ueda, K1
Li, J; Li, Y; Meng, X; Ouyang, Q; Wang, J; Xing, L; Xue, L; Yan, X; Zhang, X1
Kuang, D; Liu, J; Liu, T; Wu, Y; You, L; Zheng, Y1
Chen, JM; Chiu, SC; Chou, HY; Hsia, JY; Huang, HM; Huang, JY; Juan, CC; Lee, YC; Su, LJ; Wei, TY; Yu, CT1
Bearss, J; Gajiwala, S; Janat-Amsbury, M; Sharma, S; Sorna, V; Theisen, ER1
Liu, Q; Liu, Y; Lu, X; Luo, F; Qin, Y; Shi, L; Wang, B; Xiang, Q; Xu, W; Xu, Y1
Chitnis, N; Diehl, JA; Kita, Y; Klein-Szanto, AJ; Li, Y; Li, Z; Nakagawa, H; Natsugoe, S; Rustgi, AK; Wasik, M; Yang, Y1
Hamamoto, R; Nakamura, Y; Saloura, V1
Cai, Q; Chen, X; Dong, W; Gu, P; He, W; Huang, J; Lin, T; Wang, B; Xie, W; Xie, Y; Zhong, G1
Filatov, MV; Kovalev, RA; Semenova, EV; Shtam, TA; Volnitskiĭ, AV1
Benetti, R; Blasco, MA; Buemi, V; Dinami, R; Jordi, F; Petti, E; Schoeftner, S1
Armstrong, SA; Chen, CW1
Cleary, ML; Duque-Afonso, J; Goode, DL; Iwasaki, M; Kuo, HP; Schneidawind, D; Wei, MC; Weng, Z; Wong, SH; Zhu, L1
Liu, XJ; Wang, DY; Zhu, HG; Zhu, R; Zou, LP1
Ariyan, CE; Berger, MF; Borsu, L; Busam, KJ; Button, J; Cao, Z; Chen, Y; Chi, P; Fagin, JA; Gao, D; Hollmann, TJ; Hu, W; Ladanyi, M; Lailler, N; Landa, I; Lee, W; Merghoub, T; Murali, R; Murphy, DA; Obenauf, AC; Postow, MA; Ran, L; Sboner, A; Schwartz, GK; Scott, SN; Shah, RH; Shukla, S; Wang, L; Wiesner, T; Wong, EW; Zhang, QF; Zheng, D1
Kitanaka, C; Kurachi, H; Kuramoto, K; Nagase, S; Ohta, T; Okada, M; Sakaki, H; Seino, M; Seino, S; Suzuki, S; Takeda, H; Watarai, H1
Hof, F; Milosevich, N1
Capper, D; Franco, P; Grauvogel, J; Heiland, DH; Hirsch, M; Masalha, W; Schrimpf, D; Staszewski, O; Urbach, H; Weyerbrock, A1
Lei, PJ; Li, L; Li, YM; Wang, HY; Wei, G; Wu, M; Ye, M; Zhang, X; Zhao, J; Zhao, QY; Zheng, JY1
Antignano, F; Arrowsmith, CH; Braam, MJS; Brown, PJ; Freeman, SA; Gold, MR; Hughes, MR; McNagny, KM; Oudhoff, MJ; Owen, DR; Rattray, DG; Refaeli, I; Rossi, FMV; Sato, T; Snyder, K; Tatlock, JH; Wang, J; Wong, D; Zaph, C1
Buechele, C; Cleary, ML; Duque-Afonso, J; Gozani, O; Hansen, L; Huang, M; Ikenouye, L; Klein, BJ; Kutateladze, TG; Li, Q; Majeti, R; Martin, GM; Onishi, M; Schneidawind, D; Shen, J; Wong, SH; Zhu, F; Zhu, L1
Andricovich, J; Kai, Y; Tzatsos, A1
Ankri, S; Ehrenhofer-Murray, A; Helm, M; Jeltsch, A; Jurkowski, TP; Lyko, F; Nellen, W; Reuter, G; Schaefer, M1
Allis, CD; Josefowicz, SZ; Soshnev, AA1
Kluiver, J; Kok, K; Li, J; Osinga, J; Seelen, MA; Sijmons, RH; van den Berg, A; van Werkhoven, MB; Westers, H1
Aleksic, J; Bandiera, R; Blanco, S; Cortés-Garrido, R; Dietmann, S; Frye, M; Gkatza, N; Hussain, S; Lombard, P; Popis, M; Sajini, A; Tanna, H1
Hino, S; Kohrogi, K; Nakao, M1
Bjerkvig, R; Johannessen, TA; Mukherjee, J; Ohba, S; Pieper, RO; Ronen, SM; Viswanath, P1
Carlson, SM; Gozani, O1
Shilatifard, A; Sze, CC1
Rau, T1
Cackowski, FC; Decker, AM; Franceschi, RT; Jung, Y; Lee, E; Li, Y; Pienta, KJ; Taichman, RS; Wang, J; Yumoto, K1
Aburatani, H; Aihara, H; Cheung, E; Doiguchi, M; Hayashi, T; Higashi, M; Ikura, T; Imamura, Y; Inoue, S; Ito, T; Kato, M; Kodama, Y; Koseki, H; Mizusaki, H; Nakagawa, T; Nakayama, T; Oki, M; Takayama, KI; Takeshima, Y; Yoneda, M1
Fang, D; Gan, H; Wang, H; Zhang, Z; Zhou, H1
Bohnenberger, H; Chen, NM; Dyck, ML; Ellenrieder, V; Forster, T; Gaedcke, J; Grade, M; Griesmann, H; Hessmann, E; Johnsen, SA; Kitz, J; Koenig, AO; Lubeseder-Martellato, C; Neesse, A; Reuter-Jessen, K; Schildhaus, HU; Siveke, J; Steuber, B; Ströbel, P; Tsai, WC; Winter, T; Zhang, JS1
Pal, S; Sif, S; Wang, L1
Barretina, J; Chang, B; Elledge, SJ; Howley, PM; Liu, J; Macia, E; Mulligan, P; Ottinger, M; Pavlova, N; Shi, Y; Shi, YJ; Westbrook, TF1
Binda, O; Champagne, KS; Chang, HY; Gozani, O; Hung, T; Johnson, K; Kuo, AJ; Kutateladze, TG; Simon, MD1
Arita, A; Costa, M; Li, Q; Sun, H; Zhou, X1
Allis, CD; Casadio, F; Dormann, HL; Li, H; Luo, JL; Patel, DJ; Song, J; Wang, GG; Wang, Z1
Akagi, K; Ishimura, A; Kimura, H; Sugano, S; Suzuki, T; Suzuki, Y; Terashima, M1
Armstrong, SA; Feng, Z; Krivtsov, AV1
Cowling, VH1
Anglim, PP; Caballería, J; Embade, N; Fernández-Ramos, D; Finnell, RH; Gorospe, M; Laird-Offringa, IA; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-Lopez, N; Mato, JM; Varela-Rey, M; Vázquez-Chantada, M; Wagner, C; Woodhoo, A1
Issa, JP1
Slany, RK1
Kai, M; Suzuki, H; Toyota, M1
Cho, YJ; Koellhoffer, EC; Lemieux, ME; McKenna, ES; Orkin, SH; Pomeroy, SL; Roberts, CW; Shen, X; Wang, X; Wilson, BG1
Achille, NJ; Chang, MJ; Chou, CW; Hemenway, CS; Reisenauer, MR; Wu, H; Zeleznik-Le, NJ; Zhang, W1
Ohno, M; Okamura, K; Tsutsui, T1
Kimura, H; Okada, M; Oneyama, C; Suzuki, K; Tajima, S1
Cabarcas, SM; Crea, F; Danesi, R; Farrar, WL; Hurt, EM; Marquez, VE; Mathews, LA; Sun, L1
Füllgrabe, J; Joseph, B; Kavanagh, E1
Arnoldo, L; Brady, L; Cravello, L; Giancotti, V; Manfioletti, G; Maurizio, E; Sgarra, R; Spolaore, B1
Armstrong, SA; Bernt, KM; Bullinger, L; Daigle, A; Faber, J; Feng, Z; Krivtsov, AV; Kung, AL; Pollock, RM; Punt, N; Richon, VM; Sinha, AU; Vempati, S; Zhu, N1
Chakraborty, J; Ghosh, A; Ghosh, S; Maiti, GP; Mukherjee, N; Mukherjee, S; Panda, CK; Roy, A; Roychoudhury, S1
Chen, K; Cheung, P; Garcia, BA; Gozani, O; Kioi, M; Kuo, AJ; Lauring, J; Li, W; Park, BH; Shi, X; Xi, Y; Zee, BM1
Chiou, YY; Fu, SL; Lin, CH; Lin, WJ1
Carr, SM; Cho, EC; Coutts, AS; Kerr, DJ; Kessler, B; Khan, O; Konietzny, R; Liu, G; Lu, YC; McGouran, J; Moehlenbrink, J; Munro, S; Stimson, L; Thangue, NB; Zheng, S1
Demidem, A; Israel, M; Morvan, D; Schwartz, L; Steyaert, JM1
Akasu, T; Atomi, Y; Cho, HS; Dohmae, N; Field, HI; Hamamoto, R; Hayami, S; Iwai, Y; Kobayashi, T; Kogure, M; Maejima, K; Masuda, A; Nakamura, Y; Ohnuma, S; Ponder, BA; Sugiyama, M; Takawa, M; Toyokawa, G; Tsunoda, T; Ueda, K; Yamane, Y1
Adamopoulos, C; Gargalionis, AN; Papavassiliou, AG; Piperi, C1
Alenda, C; Guarinos, C; Jover, R; Payá, A; Rodríguez-Soler, M; Sánchez-Fortún, C1
Al-Sohaily, S; Biankin, A; Kohonen-Corish, M; Leong, R; Warusavitarne, J1
Amstislavskiy, V; Ast, V; Avci, M; Bartholomae, CC; Bender, S; Benes, V; Betts, MJ; Brors, B; Cho, YJ; Cin, H; Clifford, SC; Coco, S; Collins, VP; Ebinger, M; Eils, J; Eils, R; Felsberg, J; Frühwald, MC; Graf, N; Hans, V; Hasselblatt, M; Herold-Mende, C; Hovestadt, V; Hutter, B; Hutter, S; Jabado, N; Jäger, N; Jones, DT; Kabbe, R; Kim, YJ; Kool, M; Korbel, JO; Korshunov, A; Koster, J; Kulozik, AE; Lasitschka, B; Lawerenz, C; Lehrach, H; Lichter, P; Maass, E; McCabe, MG; Meyerson, M; Milde, T; Monoranu, C; Northcott, PA; Pfaff, E; Pfister, SM; Pleier, S; Pomeroy, SL; Pugh, TJ; Raeder, B; Rausch, T; Reifenberger, G; Remke, M; Roggendorf, W; Rössler, J; Russell, RB; Rutkowski, S; Ryzhova, M; Scheurlen, W; Schmidt, M; Schuhmann, MU; Schüller, U; Shih, D; Sieber, L; Sturm, D; Stütz, AM; Sultan, M; Taylor, MD; Tonini, GP; Tzaridis, T; Unterberg, A; van Sluis, P; Volckmann, R; von Bueren, AO; von Deimling, A; von Kalle, C; Wang, Q; Warnatz, HJ; Weber, UD; Weischenfeldt, J; Wiemann, S; Williamson, D; Witt, H; Witt, O; Wittmann, A; Wolf, S; Yaspo, ML; Zapatka, M; Zichner, T1
Abdel-Wahab, O; Adli, M; Aifantis, I; Bernstein, BE; Carroll, M; Chung, YR; Gao, J; Hricik, T; Jaffe, JD; Koche, R; LaFave, LM; Levine, RL; Melnick, A; Nimer, SD; Pandey, S; Park, CY; Patel, JP; Perna, F; Shih, AH; Taylor, JE; Zhao, X1
Jackson, JB; Pallas, DC1
Peng, X; Qiang, B; Tan, X; Wang, S; Yang, B; Yin, B; Yuan, J1
Chen, Z; Dou, Y; Viboolsittiseri, SS; Wang, JH; Yan, CT1
Avila, MA; Berasain, C; Corrales, FJ; Elizalde, M; Garcia-Irigoyen, O; Latasa, MU; Nicou, A; Perugorría, MJ; Prieto, J; Recio, JA; Salis, F; Urtasun, R1
Bian, YQ; Chen, F; Dang, J; Dong, GY; Gao, S; Kjems, J; Liu, Q; Sun, JY; Wang, QT; Wang, XW1
Arai, Y; Ariga, T; Furukawa, S; Haruta, M; Ichikawa, M; Kajii, T; Kaneko, Y1
Gong, Y; Hu, H; Ji, Q; Jiang, B; Li, X; Liu, Q; Liu, R; Shang, Y; Shao, C; Wang, Y; Yang, Y; Yuan, J; Zhao, W; Zou, Y1
Gozani, O; Hammell, M; Joshua-Tor, L; Kuo, A; McCombie, WR; Mills, AA; Paul, S; Schalch, T; Vogel, H1
Drobná, Z; Jaspers, I; Lin, S; Stýblo, M; Thomas, DJ1
Di Mario, A; Guidi, F; Hohaus, S; Leone, G; Pagano, L; Scardocci, A; Voso, MT; Zini, G1
Kaina, B1
Fujimura, T; Fujita, M; Horie-Inoue, K; Inoue, S; Kitamura, T; Kumagai, J; Ouchi, Y; Sasano, H; Suzuki, T; Takahashi, S; Urano, T1
Altamura, S; Di Bernardo, J; Fusco, A; Giancotti, V; Manfioletti, G; Rustighi, A; Sgarra, R; Tessari, MA1
Amada, S; Furuya, T; Hirakawa, T; Kawasaki, K; Kawauchi, S; Liu, XP; Oga, A; Sasaki, K1
Aoyagi, Y; Honma, T; Igarashi, M; Kawai, H; Mita, Y; Nakamura, A; Suda, T; Takahashi, T; Waguri, N1
Farraye, FA; Mack, C; O'Brien, MJ; Posnik, O; Yang, S1
Coffield, VM; Feng, Q; Jiang, Q; Li, Y; Lin, Y; Okada, Y; Su, L; Xu, G; Zhang, Y1
Braig, M; Dörken, B; Jenuwein, T; Lee, S; Loddenkemper, C; Peters, AH; Rudolph, C; Schlegelberger, B; Schmitt, CA; Stein, H1
Kelsey, KT; Kraunz, KS; Liu, M; Nelson, HH; Wiencke, JK1
Cha, TL; Chen, CT; Hung, MC; Otte, AP; Ping, B; Wu, Y; Xia, W; Yang, CC; Zhou, BP1
Carvalho, AL; Henrique, R; Hoque, MO; Jerónimo, C; Lopes, C; Oliveira, J; Pais, I; Ribeiro, FR; Sidransky, D; Teixeira, MR1
Agnese, V; Augello, C; Bazan, V; Bruno, L; Calò, V; Cammareri, P; Cascio, S; Corsale, S; Gargano, G; Gerbino, A; Gregorio, V; Gullo, A; Macaluso, M; Morello, V; Passantino, R; Rinaldi, G; Russo, A; Surmacz, E; Tomasino, RM1
Fodor, BD; Jenuwein, T; Kohlmaier, A; Kubicek, S; Lachner, M; Linderson, Y; Martens, JH; O'Sullivan, RJ; Perez-Burgos, L; Peters, AH; Schotta, G; Sengupta, R; Yonezawa, M1
Golebiowski, F; Karaczyn, AA; Kasprzak, KS1
Esteller, M; Herranz, M1
Muskhelishvili, L; Pogribny, IP; Ross, SA; Rusyn, I; Tryndyak, VP1
Jass, JR; Minoo, P; Moyer, MP1
Eisenman, RN; Secombe, J1
Walle, T1
Cai, L; Kamps, MP; Pasillas, MP; Wang, GG1
Beland, FA; Boyko, A; Kovalchuk, I; Kovalchuk, O; Kutanzi, K; Latendresse, JR; Montgomery, B; Pogribny, IP; Tryndyak, VP; Warbritton, AR; Zemp, F1
Chan, LC; Cheung, N; Cleary, ML; So, CW; Thompson, A1
Chiffer, RC; Leuba, SH; Rodriguez-Collazo, P; Smith, CL; Snyder, SK; Zlatanova, J1
Armstrong, SA; Krivtsov, AV1
Abraham, JM; Agarwal, R; Beer, DG; Cheng, Y; David, S; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Mantzur, C; Meltzer, SJ; Mori, Y; Olaru, A; Paun, B; Sato, F; Wang, S; Yang, J1
Blanca, A; Carrasco, JC; Requena, MJ1
Alani, RM; Cummings, SD; Healey, MA; Meeker, AK; Ryu, B; Samuels, MA; Yu, X1
Bergo, MO; Fong, LG; Wahlstrom, AM; Young, SG1
Basilico, C; Liboi, E1
Hoffman, RM1
Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA1
Bouck, N; Kokkinakis, D; Ostrowsky, J1
Romanov, GA; Vaniushin, BF1
Doerfler, W1
Berns, A; Quint, W; van der Putten, H; Verma, IM1
Diala, ES; Hoffman, RM1
Dina, D; Escobedo, J; Gattoni, S; Kirschmeier, P; Weinstein, IB1
Ishiwata, K; Oikawa, A1
Doerfler, W; Renz, D; Vardimon, L1
Blennerhassett, G; Groffen, J; Heisterkamp, N; Stephenson, JR1
Doerfler, W; Eick, D; Kron, B; Kruczek, I; Vardimon, L1
Arya, SK1
Groner, B; Günzburg, WH1
Magee, PN; Nyce, J; Weinhouse, S1
Fisher, PB1
Nicolson, GL1
Goodfellow, PN1
Weinhouse, S1
Osawa, T; Tarutani, O; Tsuji, T; Yamamoto, K1
Baumgartner, J; Dunnick, W; Fradkin, L; Schultz, C1
Borek, C; Cleaver, JE; Ong, A1
Cline, MJ; deKernion, JB; Slamon, DJ; Verma, IM1
Cedar, H; Gruenbaum, Y; Naveh-Many, T; Razin, A; Sciaky-Gallili, N; Stein, R1
Harbers, K; Jaenisch, R; Jähner, D; Stewart, CL; Stuhlmann, H1
Boehm, TL; Drahovsky, D1
Godburn, KE; Nazar, RN; Sitz, TO; Somers, KD1
DiBerardino, MA; Etkin, LD; Hoffner, NJ1
Pegg, AE1
Cassileth, PA; Cooper, RA; Suholet, D1
Erickson, LC; Kohn, KW; Laurent, G; Sharkey, NA1
Grisham, JW; Kaufman, DG; Smith, GJ1
Montesano, R1
Blann, E; Hammons, GJ; Lyn-Cook, BD; Nichols, J; Warren, GJ1
Counts, JL; Goodman, JI1
Little, M; Wainwright, B1
Hölttä, E; Laitinen, J; Saris, P1
Almeida, A; Dutrillaux, B; Jeanpierre, M; Kokalj-Vokac, N; Malfoy, B; Viegas-Péquignot, E1
MacLeod, AR; Rouleau, J; Szyf, M1
Doerfler, W; Heller, H; Kämmer, C; Wilgenbus, P1
Buss, JE; Cochrane, CG; Der, CJ; Jackson, JH; Li, JW1
Jaenisch, R; Laird, PW1
Kwan, WK; Qiu, R; Schimmer, BP; Tsao, J1
Kadam, S; McAlpine, JB1
Coetzee, GA; Eversole-Cire, P; Gonzales, FA; Hustad, CM; Jones, PA; Rideout, WM; Spruck, CH1
Klock, G; List, HJ; Patzel, V; Rühl, G; Schopen, A; Stollwerk, J; Zeidler, U1
Colburn, NH; Oberley, LW; Sun, Y1
Bassett, DE; Baylin, SB; Herman, J; Issa, JP; Nelkin, BD; Wu, J1
Baylin, SB; Harris, CC; Spillare, EA; Vertino, PM1
Baylin, SB; de Bustros, A; Herman, JG; Lee, RY; Mabry, M; Nelkin, BD; Wilson, G; Wu, J; Yen, RW1
Beart, RW; Jones, PA; Nguyen, TT; Schmutte, C; Yang, AS1
Brent, TP; Harris, LC; Howell, SR; Remack, JS; Venable, CC; von Wronski, MA1
Baylin, SB; Belinsky, SA; Issa, JP; Nikula, KJ1
Heby, O1
Ge, X; Kamada, N; Tanaka, K1
Chaves, P; Costa Mira, F; Cravo, M; Fidalgo, P; Glória, L; Nobre-Leitão, C; Pinto, R1
Aquilina, G; Bignami, M1
Ira, G1
Gu, H; Kim, S; Lee, HW; Lim, IK; Paik, WK; Park, GH; Park, SH1
Jin, M; Jung, HJ; Kim, CG; Kim, H; Kim, NG; Park, C; Park, JH; Piao, Z; Shin, EC1
Berchem, G; Dicato, M; Duhem, C; Ries, F1
Shou, J; Wu, D; Zhang, Y1
Bosserhoff, AK; Buettner, R; de Herreros, AG; Domínguez, D; Poser, I; Varnai, A1
Freedman, AN; Ishibe, N1
Badawi, AF; Cavalieri, EL; Higginbotham, S; Kumar, S; Rogan, EG; Todorovic, R1
Chakraborty, S; Nucifora, G; Senyuk, V1
Hamilton, SR1
Hawkins, NJ; Ward, RL1
Klochendler-Yeivin, A; Yaniv, M1
Asp, J; Benassi, MS; Brantsing, C; Gamberi, G; Gobbi, GA; Magagnoli, G; Molendini, L; Pazzaglia, L; Picci, P; Ragazzini, P; Sangiorgi, L1
Chen, C; Chen, W; Nallusamy, S; Novetsky, AD; Wang, JC1
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN1
Browne, MJ; Burdon, RH1
Lawrence, F; Pierré, A; Richou, M; Robert-Géro, M; Vigier, P1
Kobliakov, VA1
Holliday, R1
Azizov, IuM; Burtseva, NN; Demidkina, NP; Vaniushin, BF1
Smirnova, IA1
Hancock, RL1
Hirose, S; Kato, M; Kodama, S; Okada, S; Ono, T; Sasaki, MS; Tawa, R; Uehara, Y; Yasuzawa, K1
Jones, PA; Rideout, WM; Shen, JC; Spruck, CH; Tsai, YC1
Chieco-Bianchi, L; Forino, M; Majone, F; Saggioro, D; Turchetto, L1
Buss, JE; Cox, AD; Der, CJ; Graham, SM; Hisaka, MM; Kato, K1
Fujitani, Y; Horio, K; Iwamoto, A; Kawabata, M; Lee, G; Odawara, T; Sudo, K; Yoshikura, H1
Guernsey, DL; Thomas, JE1
Bassin, RH; Rimoldi, D; Samid, D; Srikantan, V; Wilson, VL1
Lawe, D; Prendergast, GC; Ziff, EB1
DiMaria, P; Duerre, JA; Kim, S; Paik, WK1
Beenken, SW; Karsenty, G; Lozano, G; Raycroft, L1
Prendergast, GC; Ziff, EB1
Smith, SS1
Ferluga, J1
Adany, R; Iozzo, RV1
Barrett, JC; Ebert, R; Pechan, R; Reiss, E; Röllich, G; Schiffmann, D; Wiseman, RW1
Hiraizumi, S; Kobata, A; Kochibe, N; Shiroki, K; Takasaki, S1
Coetzee, GA; Gonzales, FA; Jones, PA; Marziasz, CM; Rideout, WM; Tapscott, SJ; Wolkowicz, MJ1
Gattoni-Celli, S; Hsiao, WL; Weinstein, IB2
Suk, WA1
Jones, PA1
de Haan, JB; Gevers, W; Parker, MI1
Nettesheim, P; Walker, C1
Bongarzone, I; Borrello, MG; Della Porta, G; Donghi, R; Mondellini, P; Pierotti, MA1
Bloemers, HP; Roebroek, AJ; van de Ven, WJ1
Kuratomi, Y; Kuwano, M; Masumi, S; Ono, M; Yasutake, C1
Biedler, JL; Melera, PW; Michitsch, RW1
Bongarzone, I; Borrello, MG; Cattadori, MR; Della Porta, G; Donghi, R; Mondellini, P; Pierotti, MA; Traversari, C1
Szpirer, C; Vanhamme, L1
Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R1
Cole, MD; Mango, SE; Schuler, GD; Steele, ME1
Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS1
Lee, RM; Ouellette, AJ; Weitzman, SA1
He, ZX; Wu, GL; Xue, JY1
Archer, MC; Brown, K; Hirani-Hojatti, S; Kovnat, A; Milligan, JR1
Avvedimento, VE; Berlingieri, MT; Di Fiore, PP; Di Lauro, R; Fusco, A; Musti, AM1
Hamburger, J; Kotler, M; Moskowitz, H; Relevy, H; Roguel, N1
Burnett, TS; Gallimore, PH1
Beato, M1
Dobrzanski, P; Doerfler, W; Knebel, D; Knust-Kron, B; Langner, KD; Weyer, U1
Boss, GR; Erbe, RW; Levitt, LJ1
Cochran, BH; Hayes, TE; Kitchen, AM1
Breznik, T; Butel, JS; Cohen, JC; Gama-Sosa, MA; Medina, D1
Kurian, P; Milo, GE; Ribovich, ML1
Chriqui-Zeira, E; Kedar, E; Mann, V; Razin, A; Szyf, M1
Atchison, ML; Kelley, DE; Perry, RP; Pollok, BA1
del Senno, L; Hanau, S; Mollica, G; Pansini, FS; Piva, R; Rimondi, AP1
Marsilio, E; Smith, BD1
Spandidos, DA1
Baylin, SB; Burke, PJ; de Bustros, A; Fearon, ER; Nelkin, BD; Sharkis, SJ; Staal, SP; Vogelstein, B1
Fidler, IJ; Frost, P1
Munholland, JM; Nazar, RN1
Day, RS; DiPaolo, JA; Doniger, J1
Khodosova, IA1
D'Ambrosio, SM; Wani, AA; Wani, G1
Hopkins, RC1
Chorváth, B; Duraj, J; Sedlák, J1
Goldstein, S; Shmookler Reis, RJ1
D'Ambrosio, SM; Kamat, PL; Kumari, HL; Milo, GE; Witiak, DT1
Brière, N1
Ivankovic, S; Schmähl, D; Zeller, WJ1
Belitsky, GA; Bogush, TA; Shabad, LM1
Dubbs, DR; Kit, S; Nakajima, K1
Gallagher, RE; Gallo, RC; Ting, RC1
Shearer, RW; Smuckler, EA1
Culp, LA; Kolodny, GM; Rosenthal, LJ1
Malec, J1
Klagsbrun, M1
Newton, AA; Rubery, ED1
Nass, MM1
McCarty, KS1
Goth, R; Rajewsky, MF1
Gantt, RR2
Macgillivray, AJ; Paul, J; Threlfall, G1
Borek, E; Kerr, SJ1
Hartenstein, R; Rabes, HM; Ringelmann, W1
Benoit, A; Chauveau, J1
Bertram, JS; Heidelberger, C; Peterson, AR1
Evans, VJ; Gantt, R1
Blair, DG; Dell'Orco, RT; Morgan, JF1
Magee, PN1
Goldman, M; Griffin, AC1
Hacker, B; Maag, TA; Mandel, LR1
Pillinger, DJ; Wilkinson, R1
Chaney, SQ; Halpern, BC; Halpern, RM; Smith, RA1
Gallo, RC2
Evans, VJ; Gantt, R; Quinn, CE1
Turkington, RW1

Reviews

67 review(s) available for isomethyleugenol and Cell Transformation, Neoplastic

ArticleYear
Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer.
    Journal of hematology & oncology, 2020, 05-19, Volume: 13, Issue:1

    Topics: Adenosine; Cell Physiological Phenomena; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Methylation; Methyltransferases; Models, Biological; Multienzyme Complexes; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Biosynthesis; Radiation Tolerance; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Neoplasm

2020
EZH2: a novel target for cancer treatment.
    Journal of hematology & oncology, 2020, 07-28, Volume: 13, Issue:1

    Topics: Adenosine; Antineoplastic Agents; Benzamides; Biphenyl Compounds; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Histone Code; Histones; Humans; Methylation; Morpholines; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship; Transcriptional Activation; Tumor Microenvironment

2020
Mechanistic insights into KDM4A driven genomic instability.
    Biochemical Society transactions, 2021, 02-26, Volume: 49, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Genomic Instability; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction

2021
Effects of m6A modifications on signaling pathways in human cancer (Review).
    Oncology reports, 2021, Volume: 45, Issue:4

    Topics: Adenosine; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasms; RNA Processing, Post-Transcriptional; Signal Transduction

2021
Impact of One-Carbon Metabolism-Driving Epitranscriptome as a Therapeutic Target for Gastrointestinal Cancer.
    International journal of molecular sciences, 2021, Jul-06, Volume: 22, Issue:14

    Topics: Animals; Carbon; Cell Transformation, Neoplastic; Folic Acid; Gastrointestinal Neoplasms; Humans; Methylation; Mitochondria; Reactive Oxygen Species; RNA

2021
MicroRNA: an important regulator in acute myeloid leukemia.
    Cell biology international, 2017, Volume: 41, Issue:9

    Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; MicroRNAs; RNA Processing, Post-Transcriptional

2017
Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-01, Volume: 23, Issue:15

    Topics: Acetylation; Cell Transformation, Neoplastic; Chromatin; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Metabolic Networks and Pathways; Methylation; Neoplasms

2017
Aberrant Regulation of mRNA m⁶A Modification in Cancer Development.
    International journal of molecular sciences, 2018, Aug-25, Volume: 19, Issue:9

    Topics: Adenosine; Animals; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Methylation; Methyltransferases; Neoplasms; RNA, Messenger

2018
KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer.
    Seminars in cancer biology, 2019, Volume: 57

    Topics: Biomarkers, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Nuclear Proteins; Repressor Proteins; Stem Cells

2019
Epigenetic interplays between DNA demethylation and histone methylation for protecting oncogenesis.
    Journal of biochemistry, 2019, Apr-01, Volume: 165, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplasm Proteins

2019
Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis.
    Cancer metastasis reviews, 2013, Volume: 32, Issue:3-4

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; DNA Repair; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Genomic Instability; Histone Demethylases; Histones; Humans; Interphase; Methylation; Mitosis; Neoplasms; Phosphorylation; Prognosis; Protein Processing, Post-Translational; Transcriptome; Ubiquitination

2013
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2013, Volume: 91, Issue:6

    Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Drosophila melanogaster; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Humans; Isoenzymes; Methylation; Mice; Mice, Transgenic; Neoplasms; Signal Transduction

2013
Critical roles of non-histone protein lysine methylation in human tumorigenesis.
    Nature reviews. Cancer, 2015, Volume: 15, Issue:2

    Topics: Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Retinoblastoma Protein; STAT3 Transcription Factor; Tumor Suppressor Protein p53

2015
Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond.
    Experimental hematology, 2015, Volume: 43, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Delivery Systems; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein

2015
Chemical Inhibitors of Epigenetic Methyllysine Reader Proteins.
    Biochemistry, 2016, Mar-22, Volume: 55, Issue:11

    Topics: Animals; Cell Cycle; Cell Transformation, Neoplastic; Drug Delivery Systems; Epigenesis, Genetic; Humans; Methylation; Protein Processing, Post-Translational

2016
Lysine-specific histone demethylases in normal and malignant hematopoiesis.
    Experimental hematology, 2016, Volume: 44, Issue:9

    Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Regulation; Hematologic Neoplasms; Hematopoiesis; Histone Demethylases; Histones; Humans; Methylation; Signal Transduction

2016
Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.
    RNA biology, 2017, 09-02, Volume: 14, Issue:9

    Topics: Animals; Binding Sites; Catalysis; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Gene Silencing; Humans; Methylation; Nucleic Acids; Phylogeny; Protein Binding; Retroelements; Structure-Activity Relationship; Substrate Specificity

2017
Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.
    Molecular cell, 2016, 06-02, Volume: 62, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Models, Molecular; Mutation; Neoplasms; Nucleic Acid Conformation; Oncogenes; Phosphorylation; Protein Binding; Protein Conformation; Structure-Activity Relationship; Transcription, Genetic

2016
Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells.
    Cancer science, 2016, Volume: 107, Issue:9

    Topics: Animals; Cell Transformation, Neoplastic; Energy Metabolism; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone Demethylases; Histones; Humans; Methylation; Neoplasms; Phenotype

2016
Nonhistone Lysine Methylation in the Regulation of Cancer Pathways.
    Cold Spring Harbor perspectives in medicine, 2016, Nov-01, Volume: 6, Issue:11

    Topics: Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; DNA Damage; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational; Signal Transduction

2016
MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer.
    Cold Spring Harbor perspectives in medicine, 2016, Nov-01, Volume: 6, Issue:11

    Topics: Animals; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enhancer Elements, Genetic; Epigenesis, Genetic; Gene Expression; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Neoplasms; Protein Processing, Post-Translational

2016
[Pathogenetic aspects in precursor lesions of gastrointestinal tumors].
    Der Pathologe, 2016, Volume: 37, Issue:Suppl 2

    Topics: Adenomatous Polyposis Coli Protein; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Progression; DNA Mismatch Repair; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Germ-Line Mutation; Humans; In Situ Hybridization, Fluorescence; Methylation; Phenotype; Precancerous Conditions; Promoter Regions, Genetic

2016
Epigenetic changes in the myelodysplastic syndrome.
    Hematology/oncology clinics of North America, 2010, Volume: 24, Issue:2

    Topics: Acetylation; Acute Disease; Azacitidine; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Leukemia, Myeloid; Methylation; Myelodysplastic Syndromes; Neoplasms; Protein Processing, Post-Translational

2010
[Disease and epigenome analysis].
    Seikagaku. The Journal of Japanese Biochemical Society, 2010, Volume: 82, Issue:8

    Topics: Acetylation; Animals; Cell Transformation, Neoplastic; Chromatin; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genomics; Histones; Humans; Life Style; Mental Disorders; Methylation; Neoplasms; Neoplastic Stem Cells

2010
Histone onco-modifications.
    Oncogene, 2011, Aug-04, Volume: 30, Issue:31

    Topics: Acetylation; Cell Transformation, Neoplastic; Chromatin; DNA Repair; Epigenesis, Genetic; Gene Silencing; Histones; Humans; Methylation; Neoplasms; Oncogene Proteins; Protein Processing, Post-Translational

2011
Histone modifications as a pathogenic mechanism of colorectal tumorigenesis.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:8

    Topics: Acetylation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Histones; Humans; Methylation; Models, Biological; Protein Processing, Post-Translational

2012
Serrated polyposis syndrome: molecular, pathological and clinical aspects.
    World journal of gastroenterology, 2012, May-28, Volume: 18, Issue:20

    Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; CpG Islands; Humans; Intestinal Polyposis; Methylation; Proto-Oncogene Proteins B-raf

2012
Molecular pathways in colorectal cancer.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:9

    Topics: Adenomatous Polyposis Coli; Cell Transformation, Neoplastic; Chromosomal Instability; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; CpG Islands; Hamartoma Syndrome, Multiple; Humans; Methylation; Microsatellite Instability; Peutz-Jeghers Syndrome

2012
The role of biomethylation in toxicity and carcinogenicity of arsenic: a research update.
    Environmental health perspectives, 2002, Volume: 110 Suppl 5

    Topics: Animals; Arsenic; Biotransformation; Cell Line; Cell Transformation, Neoplastic; Humans; Mammals; Methylation; Methyltransferases; Transcription, Genetic

2002
Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.
    Cytogenetic and genome research, 2004, Volume: 104, Issue:1-4

    Topics: Alkylating Agents; Animals; Animals, Genetically Modified; Apoptosis; Base Pair Mismatch; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; Cricetulus; DNA; DNA Damage; DNA Repair; DNA Replication; Fibroblasts; Guanine; Guanosine; Humans; Methylation; Mice; Models, Genetic; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Recombination, Genetic; Sister Chromatid Exchange

2004
Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer.
    FEBS letters, 2004, Sep-10, Volume: 574, Issue:1-3

    Topics: Acetylation; Amino Acid Sequence; Apoptosis; Cell Transformation, Neoplastic; Chromatin; High Mobility Group Proteins; Methylation; Molecular Sequence Data; Neoplasms; Protein Conformation; Sequence Homology, Amino Acid

2004
The role of histone modifications in epigenetic transitions during normal and perturbed development.
    Ernst Schering Research Foundation workshop, 2006, Issue:57

    Topics: Animals; Cell Differentiation; Cell Lineage; Cell Transformation, Neoplastic; Chromatin; Embryonic Development; Epigenesis, Genetic; Histones; Humans; Methylation; Protein Structure, Tertiary

2006
DNA methylation and histone modifications in patients with cancer: potential prognostic and therapeutic targets.
    Methods in molecular biology (Clifton, N.J.), 2007, Volume: 361

    Topics: Acetylation; Antineoplastic Agents; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplasms; Prognosis; Protein Processing, Post-Translational; Tumor Suppressor Proteins

2007
The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection.
    Cell cycle (Georgetown, Tex.), 2007, Jun-01, Volume: 6, Issue:11

    Topics: Animals; Caenorhabditis elegans Proteins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Epigenesis, Genetic; Gene Expression Regulation; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intracellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Lysine; Mammals; Methylation; Mice; Mice, Knockout; Neoplasms; Nuclear Proteins; Nucleosomes; Oxidoreductases, N-Demethylating; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Repressor Proteins; Retinoblastoma-Binding Protein 2; Saccharomyces cerevisiae Proteins; Substrate Specificity; Tumor Suppressor Proteins

2007
Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?
    Seminars in cancer biology, 2007, Volume: 17, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chemoprevention; Flavones; Flavonoids; Humans; Methylation; Neoplasms

2007
MLL translocations, histone modifications and leukaemia stem-cell development.
    Nature reviews. Cancer, 2007, Volume: 7, Issue:11

    Topics: Adult; Animals; Cell Division; Cell Transformation, Neoplastic; Child; Chromatin; Epigenesis, Genetic; Gene Expression Regulation; Gene Expression Regulation, Developmental; Hematopoietic Stem Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Leukemia; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Prognosis; Protein Methyltransferases; Protein Processing, Post-Translational

2007
Genetic analyses of the role of RCE1 in RAS membrane association and transformation.
    Methods in enzymology, 2008, Volume: 438

    Topics: Animals; Cardiomyopathy, Dilated; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Fibroblasts; Genes, ras; Hematopoiesis; Humans; Liver; Methylation; Mice; Mice, Knockout; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myeloproliferative Disorders; Protein Processing, Post-Translational; ras Proteins; Transfection

2008
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2

    Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40

1984
[Methylation of eukaryote DNA. II. Biological significance].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1981, Issue:1

    Topics: Animals; Base Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Chromosome Aberrations; Cricetinae; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; DNA Restriction Enzymes; DNA-Directed RNA Polymerases; Gene Expression Regulation; Genes, Regulator; Histones; Methylation; Organoids; Transcription, Genetic

1981
DNA methylation--a regulatory signal in eukaryotic gene expression.
    The Journal of general virology, 1981, Volume: 57, Issue:Pt 1

    Topics: 5-Methylcytosine; Adenoviridae; Animals; Bacteriophages; Base Sequence; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Gene Expression Regulation; Genes, Viral; Herpesviridae; Insect Viruses; Methylation; Polyomavirus; Retroviridae; Simian virus 40

1981
5-Methylcytosine depletion during tumour development: an extension of the miscoding concept.
    British journal of cancer, 1983, Volume: 48, Issue:4

    Topics: 5-Methylcytosine; Alkylation; Amino Acid Metabolism, Inborn Errors; Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Cytosine; DNA; DNA Repair; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Models, Genetic; Neoplasms; Oncogenes; Rats; Tyrosine; Vitamin B 6 Deficiency

1983
Chemical-viral interactions in cell transformation.
    Cancer investigation, 1983, Volume: 1, Issue:6

    Topics: Animals; Carcinogens; Cell Adhesion; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; DNA, Neoplasm; Epidermal Growth Factor; Humans; Methylation; Phenotype

1983
Generation of phenotypic diversity and progression in metastatic tumor cells.
    Cancer metastasis reviews, 1984, Volume: 3, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Clone Cells; DNA; Humans; Methylation; Mutation; Neoplasm Metastasis; Neoplasms; Phenotype

1984
The use of cloned gene probes to study differentiation in teratocarcinomas.
    Cell differentiation, 1984, Volume: 15, Issue:2-4

    Topics: Animals; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; DNA; Enhancer Elements, Genetic; Gene Expression Regulation; Genes; Genetic Techniques; Genetics; Methylation; Mice; Neoplasm Proteins; Teratoma; Transcription, Genetic; Viral Proteins

1984
Isozyme alterations, gene regulation and the neoplastic transformation.
    Advances in enzyme regulation, 1983, Volume: 21

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Fetal Proteins; Gene Expression Regulation; Glycolysis; Hormones; Isoenzymes; Liver Neoplasms, Experimental; Methylation; Oncogenes; Rats

1983
Alterations in DNA methylation may play a variety of roles in carcinogenesis.
    Cell, 1995, Oct-06, Volume: 83, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Methylation; Mutation

1995
DNA methylation and cancer.
    Human molecular genetics, 1994, Volume: 3 Spec No

    Topics: Animals; Cell Transformation, Neoplastic; DNA Modification Methylases; DNA, Neoplasm; Gene Expression; Humans; Methylation; Mutation; Neoplasms

1994
DNA methylation and polyamines in embryonic development and cancer.
    The International journal of developmental biology, 1995, Volume: 39, Issue:5

    Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Humans; Male; Methylation; Mice; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Oogenesis; Polyamines; Replication Origin; Spermatogenesis; Transcription, Genetic

1995
Genetic instability and methylation tolerance in colon cancer.
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:1

    Topics: Cell Transformation, Neoplastic; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Damage; DNA Repair; Guanine; Humans; Methylation; Methyltransferases; Microsatellite Repeats; O(6)-Methylguanine-DNA Methyltransferase; Phenotype

1996
[CpG islands--the only unmethylated fragments of DNA in the vertebrate genome].
    Postepy biochemii, 1997, Volume: 43, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Chromatin; CpG Islands; DNA; Eukaryotic Cells; Genetic Markers; Humans; Mammals; Methylation; Vertebrates

1997
The biology of colorectal cancer.
    Seminars in oncology, 2000, Volume: 27, Issue:5 Suppl 10

    Topics: Cell Cycle; Cell Transformation, Neoplastic; Colorectal Neoplasms; Gene Expression; Genes, Tumor Suppressor; Humans; Intestinal Mucosa; Methylation; Mutation; Oncogenes

2000
Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.
    Cancer investigation, 2001, Volume: 19, Issue:5

    Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p27; Dietary Fiber; Environmental Exposure; Enzyme Inhibitors; Folic Acid; Genes, APC; Genes, bcl-2; Genes, DCC; Genes, p53; Genes, ras; Genes, Tumor Suppressor; Humans; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Microtubule-Associated Proteins; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Smoking; Tumor Suppressor Proteins

2001
Genetic lesions and perturbation of chromatin architecture: a road to cell transformation.
    Journal of cellular biochemistry, 2001, Volume: 82, Issue:2

    Topics: Acetylation; Amino Acid Motifs; Animals; Cell Transformation, Neoplastic; Chromatin; Chromosome Aberrations; CREB-Binding Protein; Dimerization; Gene Expression Regulation; Gene Targeting; Histones; Humans; Leukemia, Promyelocytic, Acute; Macromolecular Substances; Methylation; Mice; Models, Genetic; Multigene Family; Neoplasm Proteins; Nuclear Proteins; Nuclear Receptor Coactivator 2; Nucleosomes; Oncogene Proteins, Fusion; Phosphorylation; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Trans-Activators; Transcription Factors; Transcription, Genetic; Translocation, Genetic

2001
Chromatin modifiers and tumor suppression.
    Biochimica et biophysica acta, 2001, Aug-31, Volume: 1551, Issue:1

    Topics: Acetylation; Animals; Cell Transformation, Neoplastic; Chromatin; Chromosomal Proteins, Non-Histone; DNA Methylation; DNA-Binding Proteins; Genes, Tumor Suppressor; Heterochromatin; Histones; Humans; Methylation; Nuclear Proteins; Nucleosomes; Phosphorylation; Signal Transduction; SMARCB1 Protein; Trans-Activators; Transcription Factors

2001
[Transformations of polycyclic aromatic hydrocarbons in the cell].
    Voprosy onkologii, 1977, Volume: 23, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens, Environmental; Cell Transformation, Neoplastic; DNA; Drug Interactions; Endoplasmic Reticulum; Enzyme Activation; Epoxy Compounds; Free Radicals; Humans; Methylation; Microsomes; Oxidation-Reduction; Phenols; Polycyclic Compounds

1977
Methylation, mutation and cancer.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1992, Volume: 14, Issue:1

    Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplasm; Female; Genes, p53; Genetic Diseases, Inborn; Humans; Male; Methylation; Mutation; Neoplasms; Neoplasms, Experimental; Vertebrates

1992
Current status of protein methylation in carcinogenesis.
    Critical reviews in oncogenesis, 1991, Volume: 2, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Esterification; Histones; Humans; Methylation; Methyltransferases; Neoplasms; Nuclear Proteins; Proteins

1991
DNA methylation in eukaryotic chromosome stability.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Chromosomes; DNA; Humans; Methylation

1991
Potential role of anti-oncogenes in aging.
    Mechanisms of ageing and development, 1990, Apr-30, Volume: 53, Issue:3

    Topics: Aging; Cell Survival; Cell Transformation, Neoplastic; DNA; DNA Tumor Viruses; Humans; Methylation; Oncogene Proteins; Oncogenes; Phenotype

1990
Effects of 5-azacytidine and its 2'-deoxyderivative on cell differentiation and DNA methylation.
    Pharmacology & therapeutics, 1985, Volume: 28, Issue:1

    Topics: Animals; Azacitidine; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chromosomes; DNA; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Genes, Viral; Humans; Methylation; Phenotype; Species Specificity

1985
A unified theory for the development of cancer.
    Bioscience reports, 1986, Volume: 6, Issue:8

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Gene Amplification; Gene Expression Regulation; Genes, Recessive; Humans; Methylation; Mutation; Neoplasms; Oncogenes; Retroviridae; Transduction, Genetic; Translocation, Genetic

1986
[Role of enzymatic DNA methylation in cell differentiation and carcinogenesis].
    Tsitologiia, 1985, Volume: 27, Issue:3

    Topics: Animals; Base Composition; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; DNA; DNA, Neoplasm; Gene Expression Regulation; Methylation; Methyltransferases; Neoplasms, Experimental; Transcription, Genetic

1985
[Molecular aspects of leukemogenesis].
    Przeglad lekarski, 1972, Volume: 29, Issue:3

    Topics: Cell Differentiation; Cell Transformation, Neoplastic; DNA; DNA Nucleotidyltransferases; DNA, Neoplasm; Genetic Code; Humans; Leukemia; Methylation; Retroviridae; Simian virus 40

1972
Protein modification, metabolic controls, and their significance in transformation in eukaryotic cells.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:5

    Topics: Acetylation; Adenosine Triphosphate; Animals; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Contact Inhibition; Cyclic AMP; DNA Replication; Glycoproteins; Inclusion Bodies; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasms; Nucleoproteins; Oxidative Phosphorylation; Transcription, Genetic

1974
Transcriptional regulation in eukaryotic cells.
    Advances in cancer research, 1972, Volume: 15

    Topics: Acetates; Cell Differentiation; Cell Nucleus; Cell Transformation, Neoplastic; Chromatin; Chromosomes; Coliphages; DNA; Genes, Regulator; Genetic Code; Heterochromatin; Histones; Methylation; Molecular Biology; Nucleic Acid Hybridization; Nucleoproteins; Peptide Chain Initiation, Translational; Phosphoproteins; RNA; RNA Nucleotidyltransferases; Templates, Genetic

1972
The tRNA methyltransferases.
    Advances in enzymology and related areas of molecular biology, 1972, Volume: 36

    Topics: Animals; Bacteriophages; Base Sequence; Binding Sites; Biological Evolution; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; Escherichia coli; Genetics, Microbial; Methylation; Methyltransferases; Mice; Mutation; Nucleic Acid Conformation; Organ Specificity; Rats; RNA, Transfer; S-Adenosylmethionine; Virus Replication; Viruses

1972
The possible role of nucleic acid methylases in the induction of cancer.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Alkylating Agents; Alkylation; Carcinogens; Cell Transformation, Neoplastic; DNA; Ethionine; Methylation; Methyltransferases; Neoplasms; Nucleic Acids; RNA, Neoplasm; RNA, Transfer; Transferases

1971

Other Studies

277 other study(ies) available for isomethyleugenol and Cell Transformation, Neoplastic

ArticleYear
TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation.
    Cell death & disease, 2022, 09-23, Volume: 13, Issue:9

    Topics: Arginine; Bone Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Osteosarcoma; Protein-Arginine N-Methyltransferases; Repressor Proteins; STAT3 Transcription Factor

2022
The H2A.Z-KDM1A complex promotes tumorigenesis by localizing in the nucleus to promote SFRP1 promoter methylation in cholangiocarcinoma cells.
    BMC cancer, 2022, Nov-11, Volume: 22, Issue:1

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Cholangiocarcinoma; Histone Demethylases; Histones; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Methylation

2022
Chromosomal instability-associated MAT1 lncRNA insulates MLL1-guided histone methylation and accelerates tumorigenesis.
    Cell reports, 2022, 12-13, Volume: 41, Issue:11

    Topics: Carcinogenesis; Cell Transformation, Neoplastic; Chromosomal Instability; DNA Copy Number Variations; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; RNA, Long Noncoding; Uveal Neoplasms

2022
The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer.
    Journal of experimental & clinical cancer research : CR, 2023, Jan-07, Volume: 42, Issue:1

    Topics: Breast Neoplasms; Carcinogenesis; Cell Transformation, Neoplastic; Female; Humans; Methylation; Methyltransferases; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factors

2023
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6.
    Cell death & disease, 2023, 08-09, Volume: 14, Issue:8

    Topics: Carcinogenesis; Cell Cycle Proteins; Cell Transformation, Neoplastic; Humans; Methylation; Multiple Myeloma; NADH Dehydrogenase; Oxidative Phosphorylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA Splicing Factors

2023
Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.
    International journal of biological sciences, 2023, Volume: 19, Issue:12

    Topics: Arginine; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Methylation; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-fos; Repressor Proteins; Stomach Neoplasms; Transcription Factor AP-1

2023
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter.
    BMC cancer, 2023, Sep-23, Volume: 23, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Methylation; Mice; Mice, Nude; RNA; Sp1 Transcription Factor; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

2023
SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A.
    JCI insight, 2023, Oct-23, Volume: 8, Issue:20

    Topics: Carcinogenesis; Cell Transformation, Neoplastic; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Male; Matrix Metalloproteinase 1; Methylation; Prostatic Neoplasms

2023
Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.
    Cell reports, 2023, Nov-28, Volume: 42, Issue:11

    Topics: Alternative Splicing; Breast Neoplasms; Cell Transformation, Neoplastic; Exons; Female; Humans; Methylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA; Serine-Arginine Splicing Factors

2023
Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma.
    BMC cancer, 2019, Sep-03, Volume: 19, Issue:1

    Topics: Aged; Carcinoma, Renal Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Histones; Homeodomain Proteins; Humans; Kidney Neoplasms; Male; Methylation; Middle Aged; Molecular Chaperones; Mutation; Neoplasm Proteins; Polycomb Repressive Complex 2; Prognosis; Protein Binding; Survival Analysis; Transcription Factors

2019
EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway.
    Oncogene, 2020, Volume: 39, Issue:5

    Topics: Angiogenic Proteins; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Silencing; Histones; Humans; Medulloblastoma; Methylation; Peptide Fragments; Receptors, G-Protein-Coupled; Sialoglycoproteins; Tumor Suppressor Protein p53

2020
A novel KDM5A/MPC-1 signaling pathway promotes pancreatic cancer progression via redirecting mitochondrial pyruvate metabolism.
    Oncogene, 2020, Volume: 39, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Histones; Humans; Methylation; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Pancreatic Neoplasms; Pyruvic Acid; Retinoblastoma-Binding Protein 2; Signal Transduction; Transcription, Genetic

2020
CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling.
    Molecular cancer, 2019, 10-29, Volume: 18, Issue:1

    Topics: 3' Untranslated Regions; Animals; ATPases Associated with Diverse Cellular Activities; beta Catenin; Bone Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Disease Progression; DNA Helicases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Lymphoid Enhancer-Binding Factor 1; Methylation; Mice; MicroRNAs; Myosins; Neoplasm Metastasis; Osteosarcoma; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA, Circular; Wnt Signaling Pathway

2019
m
    Molecular cancer, 2019, 11-14, Volume: 18, Issue:1

    Topics: Adenosine; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Eye Neoplasms; Gene Expression Profiling; Humans; Melanoma; Methylation; Mitochondrial Proteins; Prognosis; RNA Processing, Post-Transcriptional; RNA, Messenger

2019
YTHDF1-mediated translation amplifies Wnt-driven intestinal stemness.
    EMBO reports, 2020, 04-03, Volume: 21, Issue:4

    Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Intestines; Methylation; Mice; Wnt Signaling Pathway

2020
Site-Selective Protein Chemical Modification of Exposed Tyrosine Residues Using Tyrosine Click Reaction.
    Bioconjugate chemistry, 2020, 05-20, Volume: 31, Issue:5

    Topics: Animals; Binding Sites; Biocatalysis; Cell Line, Tumor; Cell Transformation, Neoplastic; Click Chemistry; Electron Transport; Horseradish Peroxidase; Humans; Luminol; Male; Methylation; Mice; Models, Molecular; Protein Conformation; Proteins; Tyrosine

2020
Long noncoding RNA ANRIL promotes the malignant progression of cholangiocarcinoma by epigenetically repressing ERRFI1 expression.
    Cancer science, 2020, Volume: 111, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cholangiocarcinoma; Disease Models, Animal; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins

2020
PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.
    Science advances, 2020, Volume: 6, Issue:16

    Topics: Breast Neoplasms; Carcinogenesis; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Female; Humans; Methylation; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Polycomb Repressive Complex 2

2020
METTL3 Promotes Tumorigenesis and Metastasis through BMI1 m
    Molecular therapy : the journal of the American Society of Gene Therapy, 2020, 10-07, Volume: 28, Issue:10

    Topics: Adenosine; Animals; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Methylation; Methyltransferases; Mice; Mouth Neoplasms; Protein Binding; RNA, Messenger

2020
Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix.
    Cancer medicine, 2020, Volume: 9, Issue:17

    Topics: Cell Proliferation; Cell Transformation, Neoplastic; Cervix Uteri; CpG Islands; Epithelial Cells; Female; Humans; In Situ Hybridization; In Situ Hybridization, Fluorescence; Metaplasia; Methylation; Papillomaviridae; Papillomavirus Infections; Promoter Regions, Genetic; SOXB1 Transcription Factors; SOXF Transcription Factors; Squamous Intraepithelial Lesions of the Cervix; Stem Cells

2020
Expression and methylation of Dickkopf-1 in the pathogenesis and malignant transformation of oral submucous fibrosis.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2020, Volume: 49, Issue:8

    Topics: Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Humans; Methylation; Mouth Neoplasms; Oral Submucous Fibrosis

2020
METTL3 regulates m6A in endometrioid epithelial ovarian cancer independently of METTl14 and WTAP.
    Cell biology international, 2020, Volume: 44, Issue:12

    Topics: Adenosine; Aged; Carcinogenesis; Carcinoma, Endometrioid; Carcinoma, Ovarian Epithelial; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; China; Female; Gene Expression; Gene Expression Profiling; HeLa Cells; Humans; Methylation; Methyltransferases; Middle Aged; RNA Splicing Factors; RNA, Messenger; Transcriptome

2020
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia.
    Oncogene, 2020, Volume: 39, Issue:50

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic

2020
Exosome-derived long non-coding RNA ADAMTS9-AS2 suppresses progression of oral submucous fibrosis via AKT signalling pathway.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:4

    Topics: Cell Communication; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Exosomes; Gene Expression Profiling; Gene Expression Regulation; Humans; Methylation; MicroRNAs; Oral Submucous Fibrosis; Prognosis; Proto-Oncogene Proteins c-akt; RNA, Long Noncoding; Signal Transduction

2021
CircRNA-100284 activates aurora kinase B by inducing methylation of HSP70 via microRNA-217 to promote proliferation of bladder cancer cells.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:3

    Topics: Animals; Arsenites; Aurora Kinase B; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D2; Enhancer of Zeste Homolog 2 Protein; Enzyme Activation; Female; Heterografts; HSP70 Heat-Shock Proteins; Humans; Methylation; Mice; MicroRNAs; RNA, Circular; Up-Regulation; Urinary Bladder Neoplasms

2021
m
    Molecular therapy : the journal of the American Society of Gene Therapy, 2021, 06-02, Volume: 29, Issue:6

    Topics: Adenosine; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Calcium; Cell Line, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Melanoma; Methylation; RNA; RNA Interference; Uveal Neoplasms

2021
A genome-wide screen for differentially methylated long noncoding RNAs identified that lncAC007255.8 is regulated by promoter DNA methylation in Beas-2B cells malignantly transformed by NNK.
    Toxicology letters, 2021, Aug-01, Volume: 346

    Topics: Bronchi; Butanones; Cell Line; Cell Transformation, Neoplastic; DNA; DNA (Cytosine-5-)-Methyltransferase 1; Epithelial Cells; Gene Expression Regulation; Genome-Wide Association Study; Humans; Lung Neoplasms; Methylation; Nitrosamines; Promoter Regions, Genetic; Respiratory Mucosa; RNA, Long Noncoding; Up-Regulation

2021
Arginine methyltransferase PRMT3 promote tumorigenesis through regulating c-MYC stabilization in colorectal cancer.
    Gene, 2021, Jul-30, Volume: 791

    Topics: Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Neoplasm Invasiveness; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-myc; Ribosomal Proteins

2021
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
    Nature communications, 2021, 07-05, Volume: 12, Issue:1

    Topics: Acute Disease; Animals; Carcinogenesis; Cell Transformation, Neoplastic; Chromatin; HEK293 Cells; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Models, Molecular; Monomeric Clathrin Assembly Proteins; Nucleosomes; Protein Conformation; Transcription Factors; Translocation, Genetic

2021
Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis.
    Cancer cell, 2017, 04-10, Volume: 31, Issue:4

    Topics: Carcinogenesis; Cell Transformation, Neoplastic; Glioblastoma; Humans; Methylation; RNA, Messenger

2017
Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
    Cancer medicine, 2017, Volume: 6, Issue:7

    Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Humans; Methylation; Microsatellite Repeats; Phosphorylation; Polymorphism, Genetic; Protein Binding; Protein Multimerization; Receptor, ErbB-2; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering

2017
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia.
    Nature cell biology, 2017, Volume: 19, Issue:7

    Topics: Animals; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Co-Repressor Proteins; Core Binding Factor Alpha 2 Subunit; DEAD-box RNA Helicases; Gene Expression Regulation, Leukemic; Genetic Predisposition to Disease; HEK293 Cells; HL-60 Cells; Humans; K562 Cells; Leukemia; Methylation; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Phenotype; Protein Interaction Maps; Proto-Oncogene Proteins c-myc; Repressor Proteins; Ribonucleoproteins; RNA, Ribosomal; RNA, Small Nucleolar; RUNX1 Translocation Partner 1 Protein; Signal Transduction; Time Factors; Transcription Factors; U937 Cells

2017
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
    Nature cell biology, 2017, Volume: 19, Issue:9

    Topics: Acetylation; Animals; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Cells, Cultured; CREB-Binding Protein; DNA Damage; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Histones; Lymphangiogenesis; Lymphoid Progenitor Cells; Lymphoma; Lymphopoiesis; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplastic Stem Cells; Phenotype; Signal Transduction; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53

2017
DNA-dependent protein kinase plays a central role in transformation of breast epithelial cells following alkylation damage.
    Journal of cell science, 2017, Nov-01, Volume: 130, Issue:21

    Topics: Alkylating Agents; Benzaldehydes; Cell Line, Tumor; Cell Transformation, Neoplastic; Comet Assay; DNA-Activated Protein Kinase; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Golgi Apparatus; Humans; Mammary Glands, Human; Methylation; Methylnitrosourea; Protein Kinase Inhibitors

2017
EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms.
    Oncogene, 2018, 01-25, Volume: 37, Issue:4

    Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; Janus Kinase 2; Jurkat Cells; Methylation; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Mutagenesis, Site-Directed; Neoplasms; Nuclear Localization Signals; Proto-Oncogene Proteins c-vav; Recombinant Proteins; STAT3 Transcription Factor; Talin; Xenograft Model Antitumor Assays

2018
Arsenite downregulates H3K4 trimethylation and H3K9 dimethylation during transformation of human bronchial epithelial cells.
    Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:4

    Topics: Arsenites; Blotting, Western; Bronchi; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Down-Regulation; Histone Demethylases; Histone Methyltransferases; Histones; Humans; Methylation; Respiratory Mucosa

2018
X chromosome protects against bladder cancer in females via a
    Science advances, 2018, Volume: 4, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, X-Linked; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Histone Demethylases; Methylation; Mice; Mice, Knockout; Mutation; Prognosis; Sex Chromosomes; Sex Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; X Chromosome

2018
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
    Cancer cell, 2018, 07-09, Volume: 34, Issue:1

    Topics: A549 Cells; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; Methylation; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Prognosis; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Signal Transduction; Transcription Factors; Tumor Burden; YAP-Signaling Proteins

2018
Methylation and MicroRNA Profiling to Understand Racial Disparities of Prostate Cancer.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1856

    Topics: Biomarkers, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Incidence; Male; Methylation; MicroRNAs; Neoplasms; Population Groups; Prevalence; Risk Factors

2018
HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis.
    Cancer cell, 2018, 10-08, Volume: 34, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Enhancer Elements, Genetic; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Promoter Regions, Genetic

2018
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
    Cell, 2019, 01-24, Volume: 176, Issue:3

    Topics: Adult; Aged; Animals; Carcinogenesis; Cell Line; Cell Transformation, Neoplastic; Female; HEK293 Cells; Heterografts; Humans; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pancreatic Neoplasms; Peptide Elongation Factor 1; Protein Biosynthesis; Protein Processing, Post-Translational; Proteomics; Signal Transduction

2019
The expanding landscape of 'oncohistone' mutations in human cancers.
    Nature, 2019, Volume: 567, Issue:7749

    Topics: Cell Transformation, Neoplastic; Histones; Humans; Lysine; Methylation; Mutation; Neoplasms; Nucleosomes; Protein Domains; Protein Processing, Post-Translational

2019
Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-07, Volume: 38, Issue:1

    Topics: Adult; Animals; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Senescence; Disease Models, Animal; Female; Gallbladder Neoplasms; Gene Expression Regulation, Neoplastic; Heterografts; Histones; Humans; Male; Methylation; Mice; Middle Aged; Models, Biological; Prognosis; RNA Interference; RNA, Long Noncoding; Young Adult

2019
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
    Genes & development, 2013, Mar-15, Volume: 27, Issue:6

    Topics: Acetylation; Amino Acid Sequence; Animals; Cell Cycle; Cell Transformation, Neoplastic; Chromatin; DNA Damage; Gene Knockout Techniques; Genomic Instability; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; M Phase Cell Cycle Checkpoints; Methylation; Mice; Mice, Knockout; Mitosis; Protein Binding; Sirtuin 2

2013
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.
    Science (New York, N.Y.), 2013, May-03, Volume: 340, Issue:6132

    Topics: Animals; Benzeneacetamides; Cell Differentiation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glutarates; Histones; Imidazoles; Isocitrate Dehydrogenase; Methylation; Mice; Mice, SCID; Mutant Proteins; Protein Multimerization; RNA Interference; Xenograft Model Antitumor Assays

2013
Menin mediates epigenetic regulation via histone H3 lysine 9 methylation.
    Cell death & disease, 2013, Apr-11, Volume: 4

    Topics: Animals; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Fibroblasts; HEK293 Cells; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Methyltransferases; Mice; Mutation; Protein Transport; Proto-Oncogene Proteins; Repressor Proteins; Signal Transduction

2013
Arginine methylation of the c-Jun coactivator RACO-1 is required for c-Jun/AP-1 activation.
    The EMBO journal, 2013, May-29, Volume: 32, Issue:11

    Topics: Animals; Arginine; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Dimerization; HEK293 Cells; Humans; Methylation; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-jun; Rabbits; Repressor Proteins; Signal Transduction; Trans-Activators; Transcription Factor AP-1; Transcriptional Activation; Ubiquitin-Protein Ligases

2013
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Animals; B-Lymphocytes; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Gene Deletion; Gene Expression Regulation, Neoplastic; Germinal Center; Histones; Methylation; Mice; Mutation; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2

2013
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells.
    Cancer cell, 2013, Jun-10, Volume: 23, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Gene Silencing; Glioblastoma; Humans; Methylation; Mice; Phosphorylation; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor; Transplantation, Heterologous; Tumor Cells, Cultured

2013
Chronic exposure to arsenic, estrogen, and their combination causes increased growth and transformation in human prostate epithelial cells potentially by hypermethylation-mediated silencing of MLH1.
    The Prostate, 2013, Volume: 73, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Arsenic; Cell Cycle; Cell Enlargement; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Estrogens; Gene Expression; Gene Silencing; Humans; Male; Methylation; MutL Protein Homolog 1; Nuclear Proteins; Prostate

2013
Methylation markers of malignant potential in meningiomas.
    Journal of neurosurgery, 2013, Volume: 119, Issue:4

    Topics: Biomarkers, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Methylation; Middle Aged

2013
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.
    Cancer cell, 2013, Sep-09, Volume: 24, Issue:3

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasms; Peptide Chain Initiation, Translational; Prognosis; Protein Binding; Protein Biosynthesis; RNA, Ribosomal; Tumor Suppressor Protein p53

2013
Methylarsonous acid causes oxidative DNA damage in cells independent of the ability to biomethylate inorganic arsenic.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Adaptation, Physiological; Animals; Arsenic Poisoning; Arsenicals; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Humans; Liver; Male; Methylation; Multidrug Resistance-Associated Protein 2; Oxidation-Reduction; Prostate; PTEN Phosphohydrolase; Rats; Toxicity Tests, Chronic

2014
Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cells.
    Journal of cell science, 2014, Feb-15, Volume: 127, Issue:Pt 4

    Topics: Animals; Biomarkers; Blastocyst; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Embryonic Stem Cells; Genomic Instability; Histones; Humans; Methylation; Mice; Neoplasm Transplantation; Protein Processing, Post-Translational; Telomerase; Telomere; Telomere Homeostasis; Teratoma; Wnt Signaling Pathway

2014
Suppression of genome instability in pRB-deficient cells by enhancement of chromosome cohesion.
    Molecular cell, 2014, Mar-20, Volume: 53, Issue:6

    Topics: Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Centromere; Chromosomal Instability; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Cohesins; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Methylation; Retinoblastoma Protein; RNA, Small Interfering; S Phase; Signal Transduction

2014
LET-418/Mi2 and SPR-5/LSD1 cooperatively prevent somatic reprogramming of C. elegans germline stem cells.
    Stem cell reports, 2014, Apr-08, Volume: 2, Issue:4

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cellular Reprogramming; Chromatin; DNA-Binding Proteins; Down-Regulation; Female; Gene Expression Regulation; Germ Cells; Histones; Male; Methylation; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mutation; Neoplasms, Germ Cell and Embryonal; Neurons; Oxidoreductases, N-Demethylating; Protein Binding; Stem Cells

2014
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.
    Blood, 2014, Jun-19, Volume: 123, Issue:25

    Topics: Animals; B-Lymphocytes; Blotting, Western; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Profiling; Histones; Humans; Kaplan-Meier Estimate; Lymphoma; Lymphoma, B-Cell; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Polycomb Repressive Complex 2; Proto-Oncogene Proteins c-myc; Spleen

2014
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
    Nature, 2014, Jun-12, Volume: 510, Issue:7504

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Lysine; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Methylation; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Pancreatic Neoplasms; Protein Phosphatase 2; Proto-Oncogene Proteins A-raf; Signal Transduction

2014
SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
    Cancer letters, 2014, Aug-28, Volume: 351, Issue:1

    Topics: Amino Acid Sequence; Cell Proliferation; Cell Transformation, Neoplastic; HEK293 Cells; HeLa Cells; Histone-Lysine N-Methyltransferase; HSP90 Heat-Shock Proteins; Humans; Methylation; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Processing, Post-Translational

2014
Different roles for p16(INK) (4a) -Rb pathway and INK4a/ARF methylation between adenocarcinomas of gastric cardia and distal stomach.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:7

    Topics: Adenocarcinoma; Aged; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Humans; Male; Methylation; Middle Aged; Retinoblastoma Protein; Signal Transduction; Stomach; Stomach Neoplasms

2014
Suppressed expression of long non-coding RNA HOTAIR inhibits proliferation and tumourigenicity of renal carcinoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12

    Topics: Animals; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Heterografts; Histones; Humans; Kidney Neoplasms; Methylation; Mice; RNA, Long Noncoding; RNA, Small Interfering; Tumor Burden

2014
Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.
    Cellular signalling, 2014, Volume: 26, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Androgens; Animals; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Estrogen Receptor alpha; Estrogens; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Signal Transduction; Up-Regulation

2014
Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.
    BMC cancer, 2014, Oct-09, Volume: 14

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Endometrial Neoplasms; Female; Histone Demethylases; Histones; Humans; Methylation; Mice; Neoplasm Grading; Tumor Burden; Xenograft Model Antitumor Assays

2014
Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract.
    Archives of toxicology, 2016, Volume: 90, Issue:2

    Topics: Bronchi; Cell Line; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Lysine; Methylation; MicroRNAs; Mitogen-Activated Protein Kinase 7; Smoking

2016
PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers.
    Cancer discovery, 2015, Volume: 5, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Apoptosis; Arginine; Cell Transformation, Neoplastic; Cluster Analysis; Cyclin D1; Cyclin-Dependent Kinase 4; Enzyme Activation; Gene Expression Profiling; Humans; Leukemia, T-Cell; Lymphoma; Lymphoma, T-Cell; Methylation; Mice; Mutation; Oncogenes; Phosphorylation; Protein-Arginine N-Methyltransferases; Tumor Suppressor Protein p53

2015
Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation.
    Scientific reports, 2015, Feb-06, Volume: 5

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Case-Control Studies; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Cisplatin; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Lymphatic Metastasis; Male; Methylation; Middle Aged; Neoplasm Grading; Neoplasm Staging; Tumor Burden; Urinary Bladder Neoplasms

2015
[Aberrant expression of sox2 gene in malignant gliomas].
    Tsitologiia, 2014, Volume: 56, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Methylation; Primary Cell Culture; Protein Processing, Post-Translational; SOXB1 Transcription Factors; Tumor Microenvironment

2014
Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Chromosomal Proteins, Non-Histone; Epidermis; Female; Histones; Humans; Male; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; ras Proteins; Repressor Proteins; Skin Neoplasms; Telomere; Telomere Homeostasis; Telomere Shortening

2015
The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.
    Cancer cell, 2015, Aug-10, Volume: 28, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Interleukin Receptor Common gamma Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous

2015
Hepatitis B virus X protein induces the histone H3 lysine 9 trimethylation on the promoter of p16 gene in hepatocarcinogenesis.
    Experimental and molecular pathology, 2015, Volume: 99, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Genes, p16; Hepatitis B virus; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2015
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
    Nature, 2015, Oct-15, Volume: 526, Issue:7573

    Topics: Alleles; Anaplastic Lymphoma Kinase; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Introns; Isoenzymes; Lysine; Methylation; Mice; Molecular Sequence Data; Molecular Weight; Neoplasms; NIH 3T3 Cells; Oncogenes; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; RNA Polymerase II; RNA, Messenger; Signal Transduction; Transcription Initiation, Genetic

2015
GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Ovarian Neoplasms; Xenograft Model Antitumor Assays

2015
Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis.
    Journal of neuropathology and experimental neurology, 2016, Volume: 75, Issue:4

    Topics: Adult; Autoantigens; Brain Neoplasms; Cell Transformation, Neoplastic; Cluster Analysis; DNA Copy Number Variations; DNA Mutational Analysis; Genome, Human; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Neoplasms, Neuroepithelial; Proteasome Endopeptidase Complex

2016
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model.
    Clinical epigenetics, 2016, Volume: 8

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; MCF-7 Cells; Methylation; Mice; Mice, Nude

2016
SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.
    Developmental cell, 2016, Apr-04, Volume: 37, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Axin Protein; beta Catenin; Caco-2 Cells; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Humans; Intestinal Neoplasms; Intestines; MCF-7 Cells; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins; Protein Methyltransferases; RNA Interference; RNA, Small Interfering; Wnt Proteins; Wnt Signaling Pathway; YAP-Signaling Proteins

2016
ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
    Cancer discovery, 2016, Volume: 6, Issue:7

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Disease Models, Animal; DNA-Binding Proteins; F-Box Proteins; Female; Gene Expression Regulation, Leukemic; Heterografts; High-Throughput Nucleotide Sequencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Intercellular Signaling Peptides and Proteins; Jumonji Domain-Containing Histone Demethylases; Leukemia; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Nucleosomes; Promoter Regions, Genetic; Protein Binding; Transcription Factors

2016
Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma.
    Neoplasia (New York, N.Y.), 2016, Volume: 18, Issue:6

    Topics: beta-Galactosidase; Carcinoma, Renal Cell; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p18; E2F1 Transcription Factor; Epithelial Cells; Genes, Tumor Suppressor; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Kidney Neoplasms; Kidney Tubules; Methylation; RNA Interference; RNA, Small Interfering

2016
Stem cell function and stress response are controlled by protein synthesis.
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cytosine; Female; Fluorouracil; Hair Follicle; Humans; Male; Methylation; Methyltransferases; Mice; Neoplastic Stem Cells; Protein Biosynthesis; Regeneration; RNA, Transfer; Skin Neoplasms; Stem Cells; Stress, Physiological

2016
Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Astrocytes; Benzeneacetamides; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Glioma; Glutarates; Histones; Humans; Imidazoles; Isocitrate Dehydrogenase; Methylation; Mutation

2016
DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis.
    Neoplasia (New York, N.Y.), 2016, Volume: 18, Issue:9

    Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epithelial-Mesenchymal Transition; Gene Silencing; Histones; Homeodomain Proteins; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Methylation; Mice; Neoplasm Metastasis; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Kinase C-alpha; Repressor Proteins; RNA Interference; Spheroids, Cellular; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger E-box Binding Homeobox 2

2016
Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1.
    Molecular cell, 2016, 10-06, Volume: 64, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin; Cyclin D1; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Oligopeptides; Phosphorylation; Protamine Kinase; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Threonine; Ubiquitination

2016
Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.
    Cell cycle (Georgetown, Tex.), 2017, Oct-02, Volume: 16, Issue:19

    Topics: Amino Acid Substitution; Cell Line, Transformed; Cell Transformation, Neoplastic; Chondrocytes; Chromatin; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Lysine; Methionine; Methylation; Mutation; Protein Processing, Post-Translational; Signal Transduction

2017
Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.
    Gastroenterology, 2017, Volume: 152, Issue:6

    Topics: Acinar Cells; Animals; Carcinoma, Pancreatic Ductal; Cell Plasticity; Cell Proliferation; Cell Transdifferentiation; Cell Transformation, Neoplastic; Ceruletide; Cyclin-Dependent Kinase Inhibitor p16; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation; Gene Silencing; Histones; Humans; Methylation; Mice; NFATC Transcription Factors; Pancreas; Pancreatic Neoplasms; Pancreatitis, Chronic; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); Regeneration; Signal Transduction; Transcription, Genetic

2017
Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells.
    Molecular and cellular biology, 2008, Volume: 28, Issue:20

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Methylation; MicroRNAs; Protein Binding; Protein Biosynthesis; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Retinoblastoma Protein; Retinoblastoma-Like Protein p130; RNA, Messenger; RNA, Small Interfering; Transcription, Genetic

2008
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
    Molecular cell, 2008, Dec-05, Volume: 32, Issue:5

    Topics: Cell Transformation, Neoplastic; Co-Repressor Proteins; DNA-Binding Proteins; Down-Regulation; Epithelial Cells; HeLa Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydro-Lyases; Lysine; Methylation; Multiprotein Complexes; Nerve Tissue Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Protein Binding; Protein Methyltransferases; Proteins; Proto-Oncogene Mas; Receptor, trkC; Repressor Proteins; RNA Interference; Transcription, Genetic

2008
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.
    Molecular cell, 2009, Jan-30, Volume: 33, Issue:2

    Topics: Acetylation; Binding Sites; Cell Line, Tumor; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Crystallography, X-Ray; Histones; Humans; Methylation; Models, Molecular; Peptides; Protein Conformation; Substrate Specificity; Tumor Suppressor Proteins

2009
Effects of nickel, chromate, and arsenite on histone 3 lysine methylation.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Arsenites; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromates; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; Lysine; Methylation; Nickel; Potassium Compounds; Protein Processing, Post-Translational; Sodium Compounds; Time Factors

2009
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
    Nature, 2009, Jun-11, Volume: 459, Issue:7248

    Topics: Amino Acid Motifs; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Genes, Homeobox; Hematologic Neoplasms; Hematopoiesis; Hematopoietic Stem Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Magnetic Resonance Spectroscopy; Methylation; Mice; Models, Molecular; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Protein Binding; Protein Conformation; Retinoblastoma-Binding Protein 2; Transcription, Genetic; Tumor Suppressor Proteins

2009
Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene.
    Biochemical and biophysical research communications, 2009, Nov-13, Volume: 389, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylases; Histones; Jumonji Domain-Containing Histone Demethylases; Methylation; Mice; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2

2009
Transformation from committed progenitor to leukemia stem cells.
    Annals of the New York Academy of Sciences, 2009, Volume: 1176

    Topics: Animals; Cell Transformation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells

2009
Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation.
    Oncogene, 2010, Feb-11, Volume: 29, Issue:6

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cyclin D1; Humans; Kinetics; Mammary Glands, Human; Methylation; Methyltransferases; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; ras Proteins; RNA Caps; Up-Regulation

2010
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
    Gastroenterology, 2010, Volume: 138, Issue:5

    Topics: 3' Untranslated Regions; Animals; Antigens, Surface; Binding Sites; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; ELAV Proteins; ELAV-Like Protein 1; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Glycine N-Methyltransferase; Half-Life; Hepatocytes; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Liver Neoplasms; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; RNA Interference; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transfection

2010
When speed matters: leukemogenic transformation by MLL fusion proteins.
    Cell cycle (Georgetown, Tex.), 2010, Jul-01, Volume: 9, Issue:13

    Topics: Animals; Cell Transformation, Neoplastic; Drosophila melanogaster; Histones; Humans; Leukemia; Methylation; Models, Biological; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Signal Transduction

2010
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation.
    Cancer cell, 2010, Oct-19, Volume: 18, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Models, Genetic; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Repressor Proteins; SMARCB1 Protein; Stem Cells; T-Lymphocytes; Transcription, Genetic; Up-Regulation

2010
Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: Animals; Apoptosis; Cell Transformation, Neoplastic; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Leukemia, Experimental; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein

2010
Possible involvement of loss of imprinting in immortalization of human fibroblasts.
    International journal of oncology, 2011, Volume: 38, Issue:4

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; DNA Methylation; Female; Fibroblasts; Gene Expression Profiling; Genomic Imprinting; Histones; Humans; Male; Methylation; Methyltransferases; Polymorphism, Genetic; Promoter Regions, Genetic; Transcription, Genetic

2011
Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the mitogen-activated protein kinase (MAPK)/phosphatidylinositol 3-kinase (PI3K) pathway.
    The Journal of biological chemistry, 2011, May-06, Volume: 286, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Transformation, Neoplastic; Embryo, Mammalian; Epigenesis, Genetic; Fibroblasts; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histones; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Membrane Proteins; Methylation; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoproteins; Protein Processing, Post-Translational; Proto-Oncogene Proteins pp60(c-src); ras Proteins; Tumor Suppressor Proteins

2011
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer.
    Molecular cancer, 2011, Apr-18, Volume: 10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Methylation; Mice; Mice, SCID; Neoplastic Stem Cells; Polycomb-Group Proteins; Prostatic Neoplasms; Repressor Proteins; RNA, Messenger; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Conformational role for the C-terminal tail of the intrinsically disordered high mobility group A (HMGA) chromatin factors.
    Journal of proteome research, 2011, Jul-01, Volume: 10, Issue:7

    Topics: Amino Acid Sequence; Cell Transformation, Neoplastic; Chromatin; HMGA Proteins; Humans; Methylation; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteomics; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Static Electricity

2011
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
    Cancer cell, 2011, Jul-12, Volume: 20, Issue:1

    Topics: Animals; Apoptosis; Cell Cycle; Cell Differentiation; Cell Transformation, Neoplastic; Gene Rearrangement; Genetic Loci; Hematopoiesis; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Methyltransferases; Mice; Myeloid Ecotropic Viral Integration Site 1 Protein; Myeloid Progenitor Cells; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oncogene Proteins, Fusion; Protein Processing, Post-Translational

2011
Association of FANCC and PTCH1 with the development of early dysplastic lesions of the head and neck.
    Annals of surgical oncology, 2012, Volume: 19 Suppl 3

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 9; Confidence Intervals; DNA, Viral; Fanconi Anemia Complementation Group C Protein; Female; Gene Expression; Head and Neck Neoplasms; Homeodomain Proteins; Human papillomavirus 16; Human papillomavirus 18; Humans; Male; Methylation; Middle Aged; Odds Ratio; Patched Receptors; Patched-1 Receptor; Promoter Regions, Genetic; Receptors, Cell Surface; RNA, Messenger; Sequence Deletion; Xeroderma Pigmentosum Group A Protein; Young Adult

2012
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
    Molecular cell, 2011, Nov-18, Volume: 44, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Chromatin; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Mice; Mice, SCID; Multiple Myeloma; Recombinant Proteins; Repressor Proteins; Signal Transduction; Transcription, Genetic; Translocation, Genetic; Xenograft Model Antitumor Assays

2011
Proteomics analysis of in vitro protein methylation during Src-induced transformation.
    Electrophoresis, 2012, Volume: 33, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Gel, Two-Dimensional; Humans; Methylation; Protein Processing, Post-Translational; Proteins; Proteome; Proteomics; Rats; src-Family Kinases

2012
Arginine methylation controls growth regulation by E2F-1.
    The EMBO journal, 2012, Apr-04, Volume: 31, Issue:7

    Topics: Apoptosis; Arginine; Cell Line, Tumor; Cell Transformation, Neoplastic; E2F1 Transcription Factor; Gene Expression Regulation; Humans; Methylation; Protein Methyltransferases; Protein Stability; Protein-Arginine N-Methyltransferases

2012
Normal human melanocytes exposed to chronic insulin and glucose supplementation undergo oncogenic changes and methyl group metabolism cellular redistribution.
    American journal of physiology. Endocrinology and metabolism, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Blotting, Western; Cell Cycle; Cell Fractionation; Cell Transformation, Neoplastic; Child; Child, Preschool; Culture Media; DNA; Dose-Response Relationship, Drug; Glucose; Glycolysis; Humans; Hypoglycemic Agents; Insulin; Isotope Labeling; Karyotyping; Magnetic Resonance Spectroscopy; Male; Melanocytes; Methylation; Precancerous Conditions; Protein Phosphatase 2; Pyruvate Kinase; Signal Transduction; Stem Cells

2012
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
    Cancer research, 2012, Jul-01, Volume: 72, Issue:13

    Topics: Aged; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Damage; DNA Replication; Female; Histone-Lysine N-Methyltransferase; Humans; Lysine; Male; Methylation; Middle Aged; Proliferating Cell Nuclear Antigen; Real-Time Polymerase Chain Reaction; RNA, Small Interfering

2012
Dissecting the genomic complexity underlying medulloblastoma.
    Nature, 2012, Aug-02, Volume: 488, Issue:7409

    Topics: Aging; Amino Acid Sequence; beta Catenin; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Child; Chromatin; Chromosomes, Human; DEAD-box RNA Helicases; DNA Helicases; DNA-Binding Proteins; Genome, Human; Genomics; Hedgehog Proteins; High-Throughput Nucleotide Sequencing; Histone Demethylases; Humans; Medulloblastoma; Methylation; Mutation; Mutation Rate; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Patched Receptors; Patched-1 Receptor; Phosphoprotein Phosphatases; Polyploidy; Receptors, Cell Surface; Sequence Analysis, RNA; Signal Transduction; T-Box Domain Proteins; Transcription Factors; Wnt Proteins

2012
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.
    Cancer cell, 2012, Aug-14, Volume: 22, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Hematopoietic System; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Mutation; Myeloid Cells; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Protein Binding; ras Proteins; Repressor Proteins; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Up-Regulation

2012
Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner.
    Neoplasia (New York, N.Y.), 2012, Volume: 14, Issue:7

    Topics: Antigens, Polyomavirus Transforming; Carboxylic Ester Hydrolases; Cell Line; Cell Proliferation; Cell Size; Cell Survival; Cell Transformation, Neoplastic; Enzyme Activation; Gene Expression Regulation; Humans; Methylation; Protein Multimerization; Protein O-Methyltransferase; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; RNA Interference; Signal Transduction

2012
The role of protein arginine-methyltransferase 1 in gliomagenesis.
    BMB reports, 2012, Volume: 45, Issue:8

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Glioma; Histones; Humans; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous; Up-Regulation

2012
The role of a newly identified SET domain-containing protein, SETD3, in oncogenesis.
    Haematologica, 2013, Volume: 98, Issue:5

    Topics: Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cloning, Molecular; DNA End-Joining Repair; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymphoma, B-Cell; Methylation; Mice; Tumor Suppressor Protein p53

2013
Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.
    Digestive diseases (Basel, Switzerland), 2012, Volume: 30, Issue:5

    Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Transformation, Neoplastic; EGF Family of Proteins; ErbB Receptors; Gene Expression Regulation; Glycoproteins; Hepatocytes; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Liver; Liver Neoplasms; MAP Kinase Signaling System; Methylation; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha

2012
MicroRNA-137 promoter methylation in oral lichen planus and oral squamous cell carcinoma.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:4

    Topics: Adult; Age Factors; Alcohol Drinking; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Connective Tissue; Cyclin-Dependent Kinase Inhibitor p16; Epithelium; Female; Genes, p16; Humans; Lichen Planus, Oral; Male; Methylation; MicroRNAs; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Polymerase Chain Reaction; Precancerous Conditions; Promoter Regions, Genetic; Risk Factors; Sex Factors; Time Factors

2013
Meiosis error and subsequent genetic and epigenetic alterations invoke the malignant transformation of germ cell tumor.
    Genes, chromosomes & cancer, 2013, Volume: 52, Issue:3

    Topics: Adolescent; Cell Transformation, Neoplastic; Child; Child, Preschool; Chromosome Aberrations; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Epigenesis, Genetic; Female; Genomic Imprinting; Histones; Humans; Infant; Infant, Newborn; Male; Meiosis; Methylation; Mutation; Neoplasms, Germ Cell and Embryonal; Polymorphism, Single Nucleotide; snRNP Core Proteins; Uniparental Disomy

2013
CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis.
    Cancer cell, 2012, Dec-11, Volume: 22, Issue:6

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Cullin Proteins; Cyclin-Dependent Kinase Inhibitor p16; DNA-Binding Proteins; Esophageal Neoplasms; Female; Histones; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Polycomb Repressive Complex 2; PTEN Phosphohydrolase; Transcription, Genetic; Transplantation, Heterologous; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation

2012
Chd5 requires PHD-mediated histone 3 binding for tumor suppression.
    Cell reports, 2013, Jan-31, Volume: 3, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; DNA Helicases; Genetic Loci; Genome; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasms; Neuroblastoma; Peptides; Protein Binding; Structure-Activity Relationship

2013
Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes.
    Blood, 2004, Jan-15, Volume: 103, Issue:2

    Topics: Aged; Apoptosis; Apoptosis Regulatory Proteins; Bone Marrow Cells; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Death-Associated Protein Kinases; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Myelodysplastic Syndromes; Polymerase Chain Reaction

2004
14-3-3sigma is down-regulated in human prostate cancer.
    Biochemical and biophysical research communications, 2004, Jul-02, Volume: 319, Issue:3

    Topics: 14-3-3 Proteins; Apoptosis Regulatory Proteins; Biomarkers, Tumor; Cell Line, Tumor; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Down-Regulation; Exonucleases; Exoribonucleases; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Membrane Glycoproteins; Methylation; Multienzyme Complexes; Neoplasm Proteins; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Isoforms; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2004
Significance of beta-catenin and pRB pathway components in malignant ovarian germ cell tumours: INK4A promoter CpG island methylation is associated with cell proliferation.
    The Journal of pathology, 2004, Volume: 204, Issue:3

    Topics: Adolescent; Adult; beta Catenin; Cell Cycle Proteins; Cell Transformation, Neoplastic; Child; Child, Preschool; CpG Islands; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Cytoskeletal Proteins; DNA, Neoplasm; Female; Genes, p16; Germinoma; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Methylation; Mutation; Neoplasm Proteins; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Trans-Activators

2004
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:9

    Topics: Adenocarcinoma; Adenoma; Base Sequence; Biopsy, Needle; Case-Control Studies; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization; Male; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA; Sampling Studies; Sensitivity and Specificity; Telomerase

2004
BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.
    The American journal of surgical pathology, 2004, Volume: 28, Issue:11

    Topics: Adenoma; Aged; Cell Transformation, Neoplastic; Colonic Polyps; Colorectal Neoplasms; CpG Islands; Female; Humans; Male; Methylation; Middle Aged; Mutation; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); ras Proteins

2004
hDOT1L links histone methylation to leukemogenesis.
    Cell, 2005, Apr-22, Volume: 121, Issue:2

    Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Proto-Oncogenes; Recombinant Fusion Proteins; RNA, Small Interfering; Saccharomyces cerevisiae; Stem Cells; Transcription Factors; Up-Regulation

2005
Oncogene-induced senescence as an initial barrier in lymphoma development.
    Nature, 2005, Aug-04, Volume: 436, Issue:7051

    Topics: ADP-Ribosylation Factors; Animals; Apoptosis; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; Chromosomal Instability; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, ras; Heterochromatin; Lymphoma; Methylation; Methyltransferases; Mice; Mice, Transgenic; Precancerous Conditions; Repressor Proteins; Transgenes; Tumor Suppressor Protein p53

2005
Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer.
    British journal of cancer, 2005, Oct-17, Volume: 93, Issue:8

    Topics: Bone Morphogenetic Protein 3; Bone Morphogenetic Protein 6; Bone Morphogenetic Proteins; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Epigenesis, Genetic; Gene Expression Regulation; Genes, ras; Growth Differentiation Factor 10; Humans; Lung Neoplasms; Methylation; Mutation; Polymerase Chain Reaction; ras Proteins; Signal Transduction; Tumor Cells, Cultured

2005
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3.
    Science (New York, N.Y.), 2005, Oct-14, Volume: 310, Issue:5746

    Topics: 3T3 Cells; Animals; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; Chromones; COS Cells; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Regulation; HeLa Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Lysine; Methylation; Mice; Molecular Sequence Data; Morpholines; Phosphorylation; Polycomb Repressive Complex 2; Protein Binding; Protein Methyltransferases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Transcription Factors

2005
Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.
    Molecular cancer research : MCR, 2006, Volume: 4, Issue:1

    Topics: Aged; Alleles; Cell Transformation, Neoplastic; Clone Cells; Cluster Analysis; Disease Progression; Epigenesis, Genetic; Humans; Male; Methylation; Middle Aged; Neoplasm Proteins; Polymerase Chain Reaction; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms

2006
TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas.
    Journal of cellular physiology, 2006, Volume: 207, Issue:3

    Topics: Adenoma; Base Sequence; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Epigenesis, Genetic; Genotype; Humans; Methylation; Mutation; Proto-Oncogene Proteins p21(ras); Tumor Suppressor Protein p53

2006
Ni(II) affects ubiquitination of core histones H2B and H2A.
    Experimental cell research, 2006, Oct-15, Volume: 312, Issue:17

    Topics: Cell Line; Cell Transformation, Neoplastic; Histones; Humans; Lung; Methylation; Nickel; Ubiquitin; Ubiquitin-Conjugating Enzymes

2006
Methyl deficiency, alterations in global histone modifications, and carcinogenesis.
    The Journal of nutrition, 2007, Volume: 137, Issue:1 Suppl

    Topics: Animals; Cell Transformation, Neoplastic; Histones; Methylation; Rats

2007
Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis.
    The Journal of pathology, 2007, Volume: 212, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Colon; Colorectal Neoplasms; CpG Islands; Epithelial Cells; Humans; Intestinal Mucosa; Methylation; Microsatellite Instability; Models, Biological; Mutation; MutL Protein Homolog 1; Neoplasm Invasiveness; Neoplasm Proteins; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf

2007
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.
    Nature cell biology, 2007, Volume: 9, Issue:7

    Topics: Acetylation; Acute Disease; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Methylation; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; Myeloid Progenitor Cells; Nuclear Pore Complex Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Spectrophotometry, Atomic; Transcriptional Activation; Translocation, Genetic

2007
Estrogen-induced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant microRNA expression.
    Cell cycle (Georgetown, Tex.), 2007, Aug-15, Volume: 6, Issue:16

    Topics: Animals; Blotting, Western; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogens; Female; Gene Expression Regulation; Histones; Mammary Neoplasms, Experimental; Methylation; MicroRNAs; Rats

2007
Protein arginine-methyltransferase-dependent oncogenesis.
    Nature cell biology, 2007, Volume: 9, Issue:10

    Topics: Acetylation; Adaptor Proteins, Signal Transducing; Arginine; Cell Line; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; HeLa Cells; Histones; Homeodomain Proteins; Humans; Immunoprecipitation; Methylation; Mutation; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Transfection

2007
cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines.
    Experimental cell research, 2008, Jan-01, Volume: 314, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Histones; Humans; Mammary Neoplasms, Animal; Methylation; Mice; Phosphorylation; Regulatory Elements, Transcriptional; Signal Transduction

2008
Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-01, Volume: 13, Issue:21

    Topics: Biomarkers; Biomarkers, Tumor; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Methylation; Esophageal Neoplasms; Humans; Methylation; Prognosis; Promoter Regions, Genetic; Risk; RNA; Sensitivity and Specificity; Tachykinins

2007
Carcinogenesis and the hypothesis of phylogenetic reversion.
    Analytical and quantitative cytology and histology, 2007, Volume: 29, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Chemoprevention; CpG Islands; Gene Silencing; Humans; Karyometry; Methylation; Neoplasms; Phylogeny

2007
Id1 delays senescence of primary human melanocytes.
    Molecular carcinogenesis, 2008, Volume: 47, Issue:9

    Topics: Cell Division; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Foreskin; Humans; In Situ Hybridization, Fluorescence; Infant, Newborn; Inhibitor of Differentiation Protein 1; Male; Melanocytes; Methylation; Promoter Regions, Genetic; Telomere

2008
Inhibition of polyoma gene expression in transformed mouse cells by hypermethylation.
    Virology, 1984, Volume: 135, Issue:2

    Topics: Animals; Azacitidine; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; DNA Restriction Enzymes; DNA, Viral; Genes, Viral; Methylation; Mice; Mice, Inbred Strains; Mutation; Nucleic Acid Hybridization; Plasmids; Polyomavirus

1984
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
    Nucleic acids research, 1984, Jul-11, Volume: 12, Issue:13

    Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic

1984
Induction of a step in carcinogenesis that is normally associated with mutagenesis by nonmutagenic concentrations of 5-azacytidine.
    Molecular and cellular biology, 1984, Volume: 4, Issue:7

    Topics: Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; DNA; Kidney; Methylation; Mutagenicity Tests; Mutagens; Mutation

1984
Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions.
    Nucleic acids research, 1982, Jan-22, Volume: 10, Issue:2

    Topics: AKR murine leukemia virus; Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chromatin; Deoxyribonuclease I; Deoxyribonucleases; DNA Restriction Enzymes; DNA, Recombinant; Endonucleases; Leukemia, Experimental; Methylation; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus

1982
DNA methylation levels in normal and chemically-transformed mouse 3T3 cells.
    Biochemical and biophysical research communications, 1982, Feb-26, Volume: 104, Issue:4

    Topics: 5-Methylcytosine; Animals; Base Composition; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Cytosine; DNA; Methylation; Methylcholanthrene; Mice

1982
Cellular Moloney murine sarcoma (c-mos) sequences are hypermethylated and transcriptionally silent in normal and transformed rodent cells.
    Molecular and cellular biology, 1982, Volume: 2, Issue:1

    Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; DNA Restriction Enzymes; Genes; Genes, Viral; Methylation; Mice; Moloney murine leukemia virus; Muridae; Rats; Sarcoma Viruses, Murine; Transcription, Genetic

1982
Chromatin structure interferes with excision of abnormal bases from DNA.
    Biochimica et biophysica acta, 1982, Jul-30, Volume: 698, Issue:1

    Topics: Cell Line; Cell Transformation, Neoplastic; Chromatin; DNA; DNA Glycosylases; DNA Repair; Female; Herpesvirus 4, Human; Humans; Kinetics; Lymphocytes; Methylation; N-Glycosyl Hydrolases; Nucleosomes; Uracil

1982
Can DNA methylation regulate gene expression?
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84

    Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA; DNA Restriction Enzymes; DNA, Viral; Female; Genes; Humans; Methylation; Oocytes; Operon; Transcription, Genetic; Xenopus

1983
Regulation of viral and cellular oncogene expression by cytosine methylation.
    Virology, 1983, Apr-15, Volume: 126, Issue:1

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cloning, Molecular; Cytosine; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mink; Oncogenes; Rats; Recombination, Genetic; Retroviridae; Sarcoma Viruses, Feline; Transfection

1983
DNA methylation and gene activity: the adenovirus system as a model.
    Cold Spring Harbor symposia on quantitative biology, 1983, Volume: 47 Pt 2

    Topics: Adenoviridae; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA, Viral; Genes, Viral; Humans; Methylation; Operon

1983
Organization of polyoma virus DNA in mouse tumor cell lines.
    Archives of virology, 1984, Volume: 79, Issue:3-4

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chromosome Deletion; DNA Restriction Enzymes; DNA, Viral; Genes, Viral; Methylation; Mice; Polyomavirus; Recombination, Genetic; Repetitive Sequences, Nucleic Acid

1984
The chromosomal integration site determines the tissue-specific methylation of mouse mammary tumour virus proviral genes.
    The EMBO journal, 1984, Volume: 3, Issue:5

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Chromosome Mapping; Chromosomes; DNA Restriction Enzymes; Genes, Viral; Liver; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Simian virus 40; Species Specificity

1984
Structural changes of carbohydrate chains of human thyroglobulin accompanying malignant transformations of thyroid glands.
    European journal of biochemistry, 1984, Aug-15, Volume: 143, Issue:1

    Topics: Carbohydrate Conformation; Carcinoma, Papillary; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Chromatography, Gel; Humans; Magnetic Resonance Spectroscopy; Methylation; Oligosaccharides; Thyroglobulin; Thyroid Gland; Thyroid Neoplasms

1984
DNA sequences involved in the rearrangement and expression of the murine c-myc gene.
    Current topics in microbiology and immunology, 1984, Volume: 113

    Topics: Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA; DNA, Neoplasm; Humans; Kidney; Liver; Methylation; Mice; Mice, Inbred BALB C; Oncogenes; Plasmacytoma; Species Specificity; Transcription, Genetic; Translocation, Genetic

1984
Methylating and ethylating carcinogens have different requirements for poly(ADP-ribose) synthesis during malignant transformation.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Alkylating Agents; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; DNA Repair; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose

1984
Expression of cellular oncogenes in human malignancies.
    Science (New York, N.Y.), 1984, Apr-20, Volume: 224, Issue:4646

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Gene Amplification; Genes, Viral; Genital Neoplasms, Female; Humans; Kidney Neoplasms; Leukemia; Lymphoma; Methylation; Mutation; Neoplasms; Nucleic Acid Hybridization; Oncogenes; RNA, Messenger; RNA, Neoplasm; Sarcoma; Transcription, Genetic; Translocation, Genetic

1984
Effect of DNA methylation on gene expression.
    Cold Spring Harbor symposia on quantitative biology, 1983, Volume: 47 Pt 2

    Topics: Adenine Phosphoribosyltransferase; Adenoviridae; Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Genes; Globins; Humans; L Cells; Macromolecular Substances; Methylation; Teratoma

1983
Retroviruses and embryogenesis: de novo methylation activity involved in gene expression.
    Cold Spring Harbor symposia on quantitative biology, 1983, Volume: 47 Pt 2

    Topics: Animals; Blastocyst; Cell Line; Cell Transformation, Neoplastic; DNA, Viral; Embryo Implantation; Embryo, Mammalian; Female; Genes, Viral; Methylation; Mice; Moloney murine leukemia virus; Pregnancy; Transfection

1983
Alteration of enzymatic methylation of DNA cytosines by chemical carcinogens: a mechanism involved in the initiation of carcinogenesis.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Humans; Methylation; Methyltransferases; Oncogenes

1983
Significance of S-adenosylmethionine pools in the hypomethylation of ribosomal RNA during the propagation of tissue culture cells and oncogenesis.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Child; Fibroblasts; HeLa Cells; Humans; Kidney; Kinetics; Liver; Liver Regeneration; Male; Methylation; Osteosarcoma; Rats; Rats, Inbred Strains; RNA, Ribosomal; S-Adenosylhomocysteine; S-Adenosylmethionine

1983
Activation of dormant genes in specialized cells.
    Science (New York, N.Y.), 1984, Jun-01, Volume: 224, Issue:4652

    Topics: Animals; Anura; Cell Differentiation; Cell Fusion; Cell Transformation, Neoplastic; Chickens; Chromatin; DNA; Drosophila; Embryo, Mammalian; Embryo, Nonmammalian; Extremities; Gene Expression Regulation; Humans; Hybrid Cells; Iris; Methylation; Mice; Nuclear Transfer Techniques; Phenotype; Rats; Xenopus

1984
Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.
    Cancer investigation, 1984, Volume: 2, Issue:3

    Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Guanine; Humans; Liver; Methylation; Methyltransferases; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidines; Structure-Activity Relationship

1984
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
    Blood, 1981, Volume: 58, Issue:2

    Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors

1981
DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells.
    Nature, 1980, Dec-25, Volume: 288, Issue:5792

    Topics: Cell Line; Cell Transformation, Neoplastic; Cross-Linking Reagents; DNA Repair; DNA, Neoplasm; Ethylnitrosourea; Humans; Methylation; Mutation; Nitrosourea Compounds; Peptide Hydrolases

1980
Cycle-dependent removal of certain methylated bases from DNA of 10T1/2 cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Cancer research, 1981, Volume: 41, Issue:4

    Topics: Animals; Base Composition; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; DNA Replication; Interphase; Kinetics; Methylation; Methylnitronitrosoguanidine; Mice; Time Factors

1981
Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis.
    Journal of supramolecular structure and cellular biochemistry, 1981, Volume: 17, Issue:3

    Topics: Alkylation; Animals; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Dimethylnitrosamine; DNA; DNA Repair; Liver; Liver Neoplasms; Mesocricetus; Methylation; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Rats; Structure-Activity Relationship

1981
Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells.
    Cancer letters, 1995, Sep-04, Volume: 96, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; In Vitro Techniques; Methylation; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; Pancreatic Neoplasms; Rats; Rats, Inbred F344

1995
Methylation and p16: suppressing the suppressor.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Carrier Proteins; Cell Transformation, Neoplastic; Cocarcinogenesis; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; DNA; Gene Expression Regulation; Genes, Tumor Suppressor; Genomic Imprinting; Humans; Methylation; Models, Genetic; Neoplasms

1995
DNA methylation is not involved in the structural alterations of ornithine decarboxylase or total chromatin of c-Ha-rasVal 12 oncogene-transformed NIH-3T3 fibroblasts.
    Journal of cellular biochemistry, 1995, Volume: 57, Issue:4

    Topics: 3T3 Cells; Animals; Cell Cycle; Cell Line, Transformed; Cell Transformation, Neoplastic; Chromatin; DNA; Genes, ras; Methylation; Mice; Nucleotide Mapping; Ornithine Decarboxylase; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid

1995
Specific induction of uncoiling and recombination by azacytidine in classical satellite-containing constitutive heterochromatin.
    Cytogenetics and cell genetics, 1993, Volume: 63, Issue:1

    Topics: Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; DNA; DNA Damage; DNA, Satellite; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Methylation; Nucleic Acid Denaturation

1993
Regulation of DNA methylation by the Ras signaling pathway.
    The Journal of biological chemistry, 1995, May-12, Volume: 270, Issue:19

    Topics: Adrenal Cortex Neoplasms; Animals; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA, Complementary; DNA, Neoplasm; Genes, ras; GTPase-Activating Proteins; Humans; Methylation; Methyltransferases; Mice; Oncogene Protein p65(gag-jun); Promoter Regions, Genetic; Proteins; ras GTPase-Activating Proteins; ras Proteins; RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured

1995
Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-06, Volume: 92, Issue:12

    Topics: Adenoviridae; Animals; Bacteriophage lambda; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cricetinae; DNA; DNA Probes; DNA, Viral; In Situ Hybridization, Fluorescence; Mesocricetus; Methylation; Plasmids; Transcription, Genetic; Transfection; Virus Integration

1995
Polylysine domain of K-ras 4B protein is crucial for malignant transformation.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Dec-20, Volume: 91, Issue:26

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; In Vitro Techniques; Lysine; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Rats; Structure-Activity Relationship

1994
Adrenocorticotropin-resistant mutants of the Y1 adrenal cell line fail to express the adrenocorticotropin receptor.
    Journal of cellular physiology, 1995, Volume: 163, Issue:1

    Topics: Adenylyl Cyclases; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Animals; Blotting, Southern; Cell Transformation, Neoplastic; Drug Resistance; Genes; Isoproterenol; Methylation; Mice; Mutation; Receptors, Adrenergic, beta; Receptors, Corticotropin; Transcription, Genetic; Tumor Cells, Cultured

1995
Dorrigocins: novel antifungal antibiotics that change the morphology of ras-transformed NIH/3T3 cells to that of normal cells. III. Biological properties and mechanism of action.
    The Journal of antibiotics, 1994, Volume: 47, Issue:8

    Topics: 3T3 Cells; Alkyl and Aryl Transferases; Animals; Antifungal Agents; Cell Transformation, Neoplastic; Genes, ras; Mating Factor; Methylation; Mice; Oncogene Protein p21(ras); Peptides; Piperidones; Protein Biosynthesis; Protein O-Methyltransferase; Signal Transduction; Transferases

1994
Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.
    Molecular and cellular biology, 1994, Volume: 14, Issue:9

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Primers; DNA Replication; Enhancer Elements, Genetic; Gene Expression Regulation; Heterochromatin; Humans; Methylation; Mice; Molecular Sequence Data; MyoD Protein; Promoter Regions, Genetic; Restriction Mapping

1994
Methylation sensitivity of the enhancer from the human papillomavirus type 16.
    The Journal of biological chemistry, 1994, Apr-22, Volume: 269, Issue:16

    Topics: 3T3 Cells; Animals; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; DNA, Viral; Enhancer Elements, Genetic; Genes, Viral; HeLa Cells; Humans; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Papillomaviridae; Regulatory Sequences, Nucleic Acid; Transcription Factors; Transcription, Genetic; Transfection

1994
Depression of catalase gene expression after immortalization and transformation of mouse liver cells.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Catalase; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Liver; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Transcription, Genetic

1993
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Oct-01, Volume: 90, Issue:19

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dexamethasone; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Primers; Gene Expression; Kinetics; Mammary Tumor Virus, Mouse; Methylation; Mice; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Promoter Regions, Genetic; Transfection

1993
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
    Cancer research, 1993, Apr-01, Volume: 53, Issue:7

    Topics: Base Sequence; Bronchi; Calcitonin; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 3; Cytosine; DNA; Epithelium; Guanine; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Tumor Cells, Cultured

1993
Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.
    Cancer research, 1996, Feb-01, Volume: 56, Issue:3

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Death; Cell Survival; Cell Transformation, Neoplastic; Cytosine; DNA; DNA-Cytosine Methylases; Gene Expression; Gene Expression Regulation, Enzymologic; Methylation; Mice; Molecular Sequence Data; Transfection

1996
Mechanisms for the involvement of DNA methylation in colon carcinogenesis.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Base Sequence; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Complementary; DNA, Neoplasm; Escherichia coli; Humans; Intestinal Mucosa; Methylation; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymidine; Uracil-DNA Glycosidase

1996
Changes in O6-methylguanine-DNA methyltransferase expression during immortalization of cloned human fibroblasts.
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: Antigens, Polyomavirus Transforming; Blotting, Western; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Simian virus 40

1996
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-30, Volume: 93, Issue:9

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Modification Methylases; DNA-Cytosine Methylases; Gene Expression; Hyperplasia; Lung; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Mice, Inbred C3H; Nitrosamines; Species Specificity

1996
Different methylation patterns of the M-BCR gene in myeloblastic and lymphoblastic crisis of chronic myelocytic leukemia.
    Chinese medical journal, 1996, Volume: 109, Issue:4

    Topics: Blast Crisis; Cell Transformation, Neoplastic; Gene Rearrangement; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methylation; Oncogene Proteins; Oncogenes; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr

1996
Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma.
    Gut, 1996, Volume: 39, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Cell Transformation, Neoplastic; Chronic Disease; DNA, Neoplasm; Female; Gastritis; Gastritis, Atrophic; Humans; Male; Methylation; Middle Aged; Precancerous Conditions; Stomach Neoplasms

1996
Identification of highly methylated arginine residues in an endogenous 20-kDa polypeptide in cancer cells.
    Life sciences, 1999, Volume: 65, Issue:8

    Topics: Animals; Cell Extracts; Cell Transformation, Neoplastic; HeLa Cells; Humans; Methylation; Neoplasm Proteins; Protein-Arginine N-Methyltransferases; Tritium; Tumor Cells, Cultured

1999
p16 is a major inactivation target in hepatocellular carcinoma.
    Cancer, 2000, Jul-01, Volume: 89, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Gene Deletion; Genes, p16; Humans; Liver Neoplasms; Methylation; Promoter Regions, Genetic; Proteins; RNA; Transcription Factors; Tumor Suppressor Protein p14ARF; Tumor Suppressor Proteins

2000
Molecular alteration of alpha-induced transformed Syrian hamster embryo cells.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1997, Volume: 12, Issue:1

    Topics: Alpha Particles; Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Genes, myc; Genes, p53; Genes, ras; In Vitro Techniques; Mesocricetus; Methylation; Plutonium; Point Mutation

1997
Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail.
    The Journal of biological chemistry, 2001, Jul-06, Volume: 276, Issue:27

    Topics: Blotting, Western; Cadherins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Humans; Melanoma; Methylation; Oligonucleotides, Antisense; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Transcription Factor AP-2; Transcription Factors; Transfection; Tumor Cells, Cultured; Up-Regulation

2001
Imbalance of estrogen homeostasis in kidney and liver of hamsters treated with estradiol: implications for estrogen-induced initiation of renal tumors.
    Chemical research in toxicology, 2001, Volume: 14, Issue:8

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; DNA Adducts; Estradiol; Estrogens; Estrogens, Catechol; Homeostasis; Kidney; Kidney Neoplasms; Liver; Male; Mesocricetus; Methylation; Oxidoreductases; Quinones

2001
Origin of colorectal cancers in hyperplastic polyps and serrated adenomas: another truism bites the dust.
    Journal of the National Cancer Institute, 2001, Sep-05, Volume: 93, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Adenoma; Carrier Proteins; Case-Control Studies; Cell Transformation, Neoplastic; Colonic Polyps; Colorectal Neoplasms; DNA, Neoplasm; Humans; Hyperplasia; Methylation; Microsatellite Repeats; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Odds Ratio

2001
Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas.
    Journal of the National Cancer Institute, 2001, Sep-05, Volume: 93, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Adenoma; Aged; Carrier Proteins; Case-Control Studies; Cell Transformation, Neoplastic; Colonic Polyps; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Immunohistochemistry; Male; Methylation; Microsatellite Repeats; Middle Aged; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic

2001
Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma.
    Cancer, 2001, Dec-15, Volume: 92, Issue:12

    Topics: Adolescent; Adult; Biomarkers, Tumor; Bone Neoplasms; Cell Transformation, Neoplastic; Child; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Exons; Female; Fungal Proteins; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunohistochemistry; Male; Methylation; Middle Aged; Osteosarcoma; Polymerase Chain Reaction; Prognosis; Promoter Regions, Genetic; Serine Endopeptidases; Transcription, Genetic; Tumor Suppressor Protein p53

2001
Hypermethylation of the P15INK4b and P16INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation.
    British journal of haematology, 2002, Volume: 116, Issue:3

    Topics: Blotting, Southern; Cell Cycle Proteins; Cell Transformation, Neoplastic; CpG Islands; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Genes, p16; Genes, Tumor Suppressor; Humans; Leukemia; Methylation; Polymerase Chain Reaction; Precancerous Conditions; Primary Myelofibrosis; Tumor Suppressor Proteins

2002
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
    Journal of natural products, 2002, Volume: 65, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes

2002
The sequence specificity of vertebrate DNA methylation.
    Nucleic acids research, 1977, Volume: 4, Issue:4

    Topics: Animals; Base Sequence; Biological Evolution; Cell Fractionation; Cell Line; Cell Transformation, Neoplastic; Cytosine; Deoxyribonucleotides; DNA; HeLa Cells; L Cells; Methionine; Methylation; Polyomavirus; Species Specificity; Vertebrates

1977
Decreased rate of S-adenosyl-L-homocysteine metabolism: an early event related to transformation in cells infected with Rous sarcoma virus.
    Biochemical and biophysical research communications, 1977, Jun-06, Volume: 76, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Amino Acid Oxidoreductases; Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Homocysteine; Hydrolases; Methylation; Neoplasm Proteins; Proteins; S-Adenosylhomocysteine; Tumor Virus Infections

1977
A new theory of carcinogenesis.
    British journal of cancer, 1979, Volume: 40, Issue:4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Repair; Genes; Humans; Methylation; Methyltransferases; Mutagens; Mutation; Neoplasms; Phenotype; Probability

1979
[Changes in the specificity of DNA methylation in cattle blood lymphocytes under chronic lymphoid leukemia].
    Biokhimiia (Moscow, Russia), 1978, Volume: 43, Issue:11

    Topics: Animals; Cattle; Cattle Diseases; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Leukemia, Lymphoid; Lymphocytes; Methylation; Transcription, Genetic

1978
Structural alterations of the ribosomal RNA genes in leukemic cells.
    Medical oncology and tumor pharmacotherapy, 1992, Volume: 9, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA, Ribosomal; Female; Gene Amplification; Gene Rearrangement; Hematopoietic System; Leukemia; Leukemia, Erythroblastic, Acute; Male; Methylation; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Rats; Rats, Wistar; Rauscher Virus; RNA, Neoplasm; RNA, Ribosomal; Tumor Virus Infections

1992
Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XXVII. Intermediate generalizations (Part B).
    Medical hypotheses, 1992, Volume: 37, Issue:1

    Topics: alpha-Fetoproteins; Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; DNA; Fetal Proteins; Gene Expression; Liver; Methylation; Mice; Models, Biological

1992
Changes of DNA methylation in protooncogenes in the process of radiation-induced transformation of mouse m5S/1M cells in vitro.
    Cancer letters, 1992, Dec-24, Volume: 67, Issue:2-3

    Topics: Animals; Blotting, Southern; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA; Methylation; Mice; Proto-Oncogenes

1992
Studies on the mechanisms of HTLV-I leukemogenesis.
    Leukemia, 1992, Volume: 6 Suppl 3

    Topics: Cell Transformation, Neoplastic; DNA Damage; Genes, pX; HTLV-I Infections; Humans; Leukemia, T-Cell; Methylation; Micronucleus Tests; Plasmids; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1992
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; Endopeptidases; Farnesol; Methylation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras)

1992
Epigenetic control of tumor cell morphology.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:6

    Topics: Actins; Animals; Avian Sarcoma Viruses; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytoskeletal Proteins; DNA, Neoplasm; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Restriction Mapping; Sarcoma, Avian; Transplantation, Heterologous; Vinculin

1991
Altered oncogenes in UV-transformed C3H 10T1/2 mouse cells: identification of mutated H-ras allele(s).
    International journal of radiation biology, 1991, Volume: 59, Issue:1

    Topics: Alleles; Animals; Blotting, Northern; Blotting, Southern; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; In Vitro Techniques; Methylation; Mice; Mutation; Ultraviolet Rays

1991
Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Animals; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Decitabine; DNA; Genes, ras; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylation; Mice; Mice, Nude; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger

1991
Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation.
    Cell, 1991, May-03, Volume: 65, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA-Binding Proteins; Gene Expression Regulation; Genes, myc; Genes, ras; Leucine Zippers; Methylation; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Proteins c-myc; Transfection

1991
An intron binding protein is required for transformation ability of p53.
    Nucleic acids research, 1991, Sep-11, Volume: 19, Issue:17

    Topics: Animals; Base Sequence; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression; Genes, p53; Guanidine; Guanidines; Introns; Methylation; Mice; Molecular Sequence Data; Mutation; Regulatory Sequences, Nucleic Acid

1991
Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region.
    Science (New York, N.Y.), 1991, Jan-11, Volume: 251, Issue:4990

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; DNA-Binding Proteins; Genes, ras; Leucine Zippers; Macromolecular Substances; Methylation; Molecular Sequence Data; Mutagenesis; Oligonucleotide Probes; Protein Conformation; Proto-Oncogene Proteins c-myc; Rabbits; Rats; Recombinant Fusion Proteins

1991
Altered methylation of versican proteoglycan gene in human colon carcinoma.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: Blotting, Southern; Cell Transformation, Neoplastic; Chondroitin Sulfate Proteoglycans; Colon; Colonic Neoplasms; DNA; DNA, Neoplasm; Humans; Inflammation; Lectins, C-Type; Methylation; Muscle, Smooth; Reference Values; Restriction Mapping; Versicans

1990
Activation of cellular oncogenes by chemical carcinogens in Syrian hamster embryo fibroblasts.
    Environmental health perspectives, 1990, Volume: 88

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; DNA; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation; Mesocricetus; Methylation; Mutation; Proto-Oncogenes

1990
Transfection with fragments of the adenovirus 12 gene induces tumorigenicity-associated alteration of N-linked sugar chains in rat cells.
    Archives of biochemistry and biophysics, 1990, Volume: 280, Issue:1

    Topics: Adenoviridae; Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Cell Transformation, Neoplastic; Chromatography, Affinity; Genes, Viral; Glycosylation; Methylation; Molecular Sequence Data; Oligosaccharides; Rats; RNA, Messenger; Transfection

1990
De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:16

    Topics: Animals; Base Sequence; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dinucleoside Phosphates; DNA; DNA Probes; Embryo, Mammalian; Methylation; Methylcholanthrene; Mice; Molecular Sequence Data; MyoD Protein; Nuclear Proteins; Oligonucleotide Probes; Phosphoproteins; Polymerase Chain Reaction; Restriction Mapping

1990
Effects of 5-azacytidine on the progressive nature of cell transformation.
    Molecular and cellular biology, 1985, Volume: 5, Issue:7

    Topics: Animals; Azacitidine; Benzo(a)pyrene; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Methylation; Mice

1985
Interaction between nontransforming retroviruses and chemicals in cells in vitro: association with progression to neoplastic phenotypes.
    Carcinogenesis; a comprehensive survey, 1985, Volume: 9

    Topics: Animals; Azacitidine; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; DNA; Methylation; Oncogenes; Phenotype; Rats; Rats, Inbred F344; Retroviridae

1985
Effects of sodium butyrate on the synthesis and methylation of DNA in normal cells and their transformed counterparts.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Butyrates; Butyric Acid; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Methylation; Protein Biosynthesis; RNA

1986
Effects of 5-azacytidine on expression of endogenous retrovirus-related sequences in C3H 10T1/2 cells.
    Journal of virology, 1986, Volume: 57, Issue:3

    Topics: Animals; Azacitidine; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA, Viral; Fibroblasts; Genes, Intracisternal A-Particle; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred C3H; Poly A; Repetitive Sequences, Nucleic Acid; Retroviridae; RNA; RNA, Messenger; RNA, Viral; Transcription, Genetic

1986
In vitro transformation of primary rat tracheal epithelial cells by 5-azacytidine.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Animals; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Decitabine; DNA; Dose-Response Relationship, Drug; Epithelium; Male; Methylation; Methylnitronitrosoguanidine; Mutation; Rats; Rats, Inbred F344; Time Factors; Trachea

1986
DNA methylation affecting the transforming activity of the human Ha-ras oncogene.
    Cancer research, 1987, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Azacitidine; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Humans; Methylation; Mice; Oncogenes; Plasmids; Transfection

1987
Reversion to the nontransformed phenotype of Abelson murine leukemia virus-transformed cells and their subsequent retransformation.
    Virus research, 1986, Volume: 6, Issue:1

    Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; DNA Restriction Enzymes; DNA, Viral; Leukemia Virus, Murine; Lung; Methylation; Mink; Phenotype; RNA; RNA, Viral

1986
Effect of 5-azacytidine on malignant transformation of a mutant derived from the mouse BALB/c 3T3 cell line resistant to transformation by chemical carcinogens.
    Cancer research, 1987, Sep-15, Volume: 47, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Metallothionein; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1987
Modulation of N-myc expression, but not tumorigenicity, accompanies phenotypic conversion of neuroblastoma cells in prolonged culture.
    Progress in clinical and biological research, 1988, Volume: 271

    Topics: Azacitidine; Cell Line; Cell Transformation, Neoplastic; Gene Amplification; Gene Expression Regulation; Humans; Methylation; Neuroblastoma; Oncogenes; Phenotype; Time Factors; Tumor Cells, Cultured

1988
Modulation of the human Harvey-ras oncogene expression by DNA methylation.
    Oncogene research, 1988, Volume: 2, Issue:2

    Topics: Animals; Azacitidine; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA; Gene Expression Regulation; Genes, ras; Humans; Methylation; Mice; Restriction Mapping; Transfection

1988
Spontaneous and 5-azacytidine-induced revertants of methionine-dependent tumor-derived and H-ras-1-transformed cells.
    Experimental cell research, 1989, Volume: 181, Issue:1

    Topics: Animals; Azacitidine; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Culture Media; Ethyl Methanesulfonate; Homocysteine; Methionine; Methylation; Oncogenes; Tumor Cells, Cultured

1989
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
    Developmental genetics, 1989, Volume: 10, Issue:4

    Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors

1989
Germ line c-myc is not down-regulated by loss or exclusion of activating factors in myc-induced macrophage tumors.
    Molecular and cellular biology, 1989, Volume: 9, Issue:8

    Topics: Animals; Base Sequence; Bucladesine; Cell Transformation, Neoplastic; Chromatin; Colony-Stimulating Factors; Deoxyribonuclease I; DNA; Exons; Gene Expression Regulation; Humans; Macrophages; Methylation; Mice; Molecular Sequence Data; Oncogenes; RNA; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic

1989
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
    Biochemical and biophysical research communications, 1989, Oct-31, Volume: 164, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea

1989
Alterations in c-abl gene methylation in cells transformed by phagocyte-generated oxidants.
    Biochemical and biophysical research communications, 1989, Jan-16, Volume: 158, Issue:1

    Topics: Animals; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; DNA; Methylation; Mice; Mice, Inbred C3H; Neutrophils; Phagocytes; Polymorphism, Restriction Fragment Length; Proto-Oncogenes

1989
[Studies on DNA methylation in transformed mouse liver cells].
    Shi yan sheng wu xue bao, 1989, Volume: 22, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; DNA Modification Methylases; Liver; Liver Neoplasms, Experimental; Male; Methylation; Mice

1989
Activation of the c-Ha-ras-1 proto-oncogene by methylation in vitro with alpha-acetoxy-N-nitrosodimethylamine.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:2

    Topics: Animals; Blotting, Southern; Carcinogenicity Tests; Cell Line; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Gene Amplification; Gene Expression Regulation; Genes, ras; Humans; Male; Methylation; Mice; Mice, Inbred CBA; Oligonucleotide Probes; Plasmids; Proto-Oncogene Mas; Taq Polymerase; Transfection

1989
The block of thyroglobulin synthesis, which occurs upon transformation of rat thyroid epithelial cells, is at the transcriptional level and it is associated with methylation of the 5' flanking region of the gene.
    Experimental cell research, 1989, Volume: 183, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Epithelium; Genes; Kirsten murine sarcoma virus; Methylation; Rats; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Thyroglobulin; Thyroid Gland; Transcription, Genetic

1989
The methylation state of the proviruses in avian sarcoma virus transformed chick and rat cells.
    Biochimica et biophysica acta, 1987, Nov-20, Volume: 910, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; DNA Restriction Enzymes; DNA, Viral; Embryo, Mammalian; Fibroblasts; Methylation; Proviruses; Rats; Rats, Inbred Strains

1987
Introduction of cloned human papillomavirus 1a DNA into rat fibroblasts: integration, de novo methylation and absence of cellular morphological transformation.
    The Journal of general virology, 1985, Volume: 66 ( Pt 5)

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cloning, Molecular; DNA, Viral; Fibroblasts; Genes, Viral; Humans; Methylation; Papillomaviridae; Plasmids; Rats; Recombination, Genetic; Transfection

1985
Modulation of gene expression through DNA-binding proteins: is there a regulatory code?
    Haematology and blood transfusion, 1985, Volume: 29

    Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; DNA-Binding Proteins; DNA, Viral; Gene Expression Regulation; Genes; Glucocorticoids; Mammary Tumor Virus, Mouse; Methylation; Mice; Nucleic Acid Conformation; Repetitive Sequences, Nucleic Acid; Transcription, Genetic

1985
Site-specific promoter methylations and gene inactivation.
    Progress in clinical and biological research, 1985, Volume: 198

    Topics: Adenoviruses, Human; Animals; Base Sequence; Cell Nucleus; Cell Transformation, Neoplastic; DNA; DNA Restriction Enzymes; DNA, Viral; Female; Genes; Histones; Humans; Methylation; Oocytes; Promoter Regions, Genetic; Xenopus

1985
Decreased methylation rates of DNA in SV40-transformed human fibroblasts.
    Cancer, 1986, Feb-15, Volume: 57, Issue:4

    Topics: Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Methionine; Methylation; S-Adenosylmethionine; Simian virus 40

1986
Inducible binding of a factor to the c-fos regulatory region.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:5

    Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; Cells, Cultured; DNA Restriction Enzymes; DNA-Binding Proteins; Genes, Regulator; Methylation; Mice; Mice, Inbred BALB C; Proto-Oncogenes; Transcription, Genetic; Transduction, Genetic

1987
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
    Virus research, 1987, Volume: 7, Issue:1

    Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Precancerous Conditions; Recombination, Genetic; Virus Replication

1987
Specific BPDE I modification of replicating and parental DNA from early S phase human foreskin fibroblasts.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Adducts; DNA Replication; Fibroblasts; Humans; Interphase; Male; Methylation; Nucleotides

1986
Characterization of a tumorigenic murine T-lymphoid-cell line spontaneously derived from an IL-2-dependent T-cell line.
    International journal of cancer, 1986, May-15, Volume: 37, Issue:5

    Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Interleukin-2; Karyotyping; Methylation; Mice; Neoplasms, Experimental; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes, Cytotoxic

1986
The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.
    Molecular and cellular biology, 1988, Volume: 8, Issue:2

    Topics: Abelson murine leukemia virus; Animals; B-Lymphocytes; Cell Line; Cell Transformation, Neoplastic; Enhancer Elements, Genetic; Genes, Immunoglobulin; Genes, Regulator; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Methylation; Transcription, Genetic; Transfection

1988
Hypomethylated state of estrogen receptor gene in endometrial carcinomas.
    Bollettino della Societa italiana di biologia sperimentale, 1988, Volume: 64, Issue:9

    Topics: Adenocarcinoma; Cell Transformation, Neoplastic; DNA, Neoplasm; Endometrial Hyperplasia; Female; Humans; Methylation; Receptors, Estrogen; Uterine Neoplasms

1988
Methylation of the alpha 2(I) collagen gene in chemically transformed rat liver epithelial cells.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Acetoxyacetylaminofluorene; Animals; Cell Line; Cell Transformation, Neoplastic; Collagen; DNA; Electrophoresis, Agar Gel; Epithelium; Genes; Liver; Methylation; Promoter Regions, Genetic; Rats; Transcription, Genetic; Tumor Cells, Cultured

1988
Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies.
    Blood, 1987, Volume: 70, Issue:2

    Topics: Acute Disease; Calcitonin; Cell Differentiation; Cell Transformation, Neoplastic; Genes, Regulator; Humans; Leukemia; Lymphoma; Methylation

1987
Biology of metastasis.
    Cancer, 1986, Jul-15, Volume: 58, Issue:2 Suppl

    Topics: Animals; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Methylation; Mutation; Neoplasm Metastasis; Phenotype

1986
Methylation of ribosomal RNA as a possible factor in cell differentiation.
    Cancer research, 1987, Jan-01, Volume: 47, Issue:1

    Topics: Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Methylation; Neoplasms; Protein Biosynthesis; RNA, Ribosomal

1987
Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; DNA; Dose-Response Relationship, Drug; Female; Guanine; Mesocricetus; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Pregnancy

1985
Repair of DNA O-alkylation damage by various human organs.
    Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2

    Topics: Brain; Cell Transformation, Neoplastic; DNA Repair; Escherichia coli; Fetus; Humans; Intestinal Mucosa; Liver; Methylation; Organ Specificity

1985
A molecular model relating to carcinogenesis.
    Progress in clinical and biological research, 1985, Volume: 172A

    Topics: Cell Transformation, Neoplastic; Cisplatin; Cytosine; DNA; DNA, Neoplasm; Methylation; Models, Molecular; Oncogenes

1985
A simple technique for cell surface radioactive labeling of human and animal neoplastic cells: reductive methylation with formaldehyde and tritiated borohydride.
    Neoplasma, 1985, Volume: 32, Issue:4

    Topics: Animals; Borohydrides; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis; Formaldehyde; Humans; Isotope Labeling; Methylation; Neoplasm Proteins; Neoplasms; Rats; Tritium

1985
Methylation patterns in the gene for the alpha subunit of chorionic gonadotropin are inherited with variable fidelity in clonal lineages of human fibroblasts.
    Nucleic acids research, 1985, Oct-11, Volume: 13, Issue:19

    Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cells, Cultured; Chorionic Gonadotropin; Cytosine; DNA Replication; Gene Expression Regulation; Genes; Humans; Methylation

1985
A comparative study of dimethylhydrazine regioisomers and the methylazoxymethanol metabolite of 1,1- and 1,2-dimethylhydrazine in relation to transformation in human fibroblasts.
    Cancer letters, 1985, Volume: 29, Issue:3

    Topics: 1,2-Dimethylhydrazine; Azo Compounds; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dimethylhydrazines; DNA; Fibroblasts; Humans; Methylation; Methylazoxymethanol Acetate; Methylhydrazines

1985
Unmasking of proteins by in vitro methylation of rat liver RNA during azo dye carcinogenesis.
    Stain technology, 1971, Volume: 46, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coloring Agents; Cytoplasm; Histocytochemistry; Liver; Liver Neoplasms; Methods; Methylation; Microscopy; Neoplasm Proteins; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Proteins; Rats; RNA; RNA, Neoplasm; Staining and Labeling; Temperature

1971
[N-demethylation of the carcinogen dimethylnitrosamine by human embryonal tissue (author's transl)].
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1974, Volume: 81, Issue:3-4

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Dimethylamines; Embryo, Mammalian; Female; Formaldehyde; Gestational Age; Guinea Pigs; Humans; In Vitro Techniques; Liver; Maternal-Fetal Exchange; Methylation; Microsomes, Liver; Neoplasms; Nitrosamines; Pregnancy; Rats; Species Specificity; Subcellular Fractions

1974
Effect of chloramphenicol and dextramycine on the toxicity of carcinogenic hydrocarbons.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1974, Volume: 82, Issue:1

    Topics: Adrenal Cortex; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chloramphenicol; Drug Interactions; Embryo, Mammalian; Fibroblasts; In Vitro Techniques; Male; Methylation; Poisoning; Rats; Stereoisomerism; Time Factors

1974
Transfer RNA methylase activities of SV40-transformed cells and cells infected with animal viruses.
    Cancer research, 1970, Volume: 30, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Culture Techniques; DNA Viruses; Enzyme Induction; Haplorhini; Kidney; Methylation; Mice; RNA, Transfer; Simian virus 40; Simplexvirus; Thymidine Kinase; Transferases; Vaccinia virus

1970
Transfer RNA methylase alterations in polyoma transformed rat embryo culture cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:3

    Topics: Acetates; Animals; Biological Assay; Cell Transformation, Neoplastic; Culture Techniques; Escherichia coli; Methylation; Polyomavirus; Quaternary Ammonium Compounds; Rats; RNA, Transfer; S-Adenosylmethionine; Transferases; Yeasts

1971
Altered regulation of the transport of RNA from nucleus to cytoplasm in rat hepatoma cells.
    Cancer research, 1972, Volume: 32, Issue:2

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Fetus; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; RNA, Neoplasm

1972
Secretion of RNA by normal and transformed cells.
    Experimental cell research, 1972, Volume: 73, Issue:1

    Topics: Animals; Autoradiography; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Paper; Formates; Hydrolysis; In Vitro Techniques; Methionine; Methylation; Nucleotides; RNA; RNA, Neoplasm; RNA, Ribosomal; Simian virus 40; Thymidine; Trichloroacetic Acid; Tritium; Uridine

1972
The contrast between the methylation of transfer ribonucleic acid in vivo and in vitro by normal and SV40 transformed 3T3 cells.
    The Journal of biological chemistry, 1972, Dec-10, Volume: 247, Issue:23

    Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chromatography; Chromatography, DEAE-Cellulose; Clone Cells; Cytoplasm; Electrophoresis; Escherichia coli; Fibroblasts; Methylation; Mice; Mice, Inbred BALB C; Oligonucleotides; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Simian virus 40; Tritium

1972
DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).
    Biochimica et biophysica acta, 1973, Sep-28, Volume: 324, Issue:1

    Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Paper; Clone Cells; Cricetinae; Cytidine; Cytosine; Deoxyuridine; DNA; Kidney; Methionine; Methylation; Polyomavirus; Thymidine; Time Factors; Tritium; Uridine

1973
Differential methylation of mitochondrial and nuclear DNA in cultured mouse, hamster and virus-transformed hamster cells. In vivo and in vitro methylation.
    Journal of molecular biology, 1973, Oct-15, Volume: 80, Issue:1

    Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chromatography, Thin Layer; Cricetinae; Cytosine; Deoxycytidine; DNA; DNA, Mitochondrial; Escherichia coli; Kidney; L Cells; Methionine; Methylation; Methyltransferases; Mice; Phosphorus Radioisotopes; Polyomavirus; Subcellular Fractions; Tritium

1973
[Ethylation of guanine-N-7 in the nucleic acids of rat embryos and liver by ethylnitrosourea].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1971, Volume: 26, Issue:10

    Topics: Alkylation; Animals; Carbon Isotopes; Carcinogens; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; DNA; Embryo, Mammalian; Female; Guanine; Lethal Dose 50; Liver; Maternal-Fetal Exchange; Methylation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Pregnancy; Rats; RNA

1971
Is aberrant nucleic acid methylation related to malignant transformation?
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:5

    Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Forecasting; Methylation; Methyltransferases; Mice; Models, Biological; Neoplasms; RNA, Neoplasm; RNA, Transfer

1974
DNA synthesis in rat liver during early stages of azo dye-induced hepatocarcinogenesis.
    Cancer research, 1972, Volume: 32, Issue:1

    Topics: Animals; Autoradiography; Cell Division; Cell Transformation, Neoplastic; DNA, Neoplasm; Liver; Liver Neoplasms; Male; Methylation; p-Dimethylaminoazobenzene; Rats; Thymidine; Tritium

1972
[Binding to DNA and to hepatic proteins of 2 azo compounds with different carcinogenic properties].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1973, Jan-08, Volume: 276, Issue:2

    Topics: Animals; Azo Compounds; Binding Sites; Carbon Isotopes; Cell Nucleus; Cell Transformation, Neoplastic; DNA; Liver; Male; Methylation; p-Dimethylaminoazobenzene; Protein Binding; Rats; Receptors, Drug

1973
DNA damage and its repair in transformable mouse fibroblasts treated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Cancer research, 1974, Volume: 34, Issue:7

    Topics: Animals; Carbon Radioisotopes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Choline; Coliphages; DNA; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Drug; Fibroblasts; Leucine; Lipids; Methylation; Mice; Mice, Inbred C3H; Molecular Weight; Nitrosoguanidines; Proteins; Time Factors; Tritium

1974
Comparison of soluble RNA methylase capacity in paired neoplastic and nonneoplastic cell lines in vitro.
    Cancer research, 1969, Volume: 29, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Escherichia coli; Methionine; Methylation; Mice; Neoplasms; RNA, Neoplasm; RNA, Transfer; Transferases

1969
Comparative transfer RNA methylase capacity in mouse ascites tumors and in their derived tumorigenic and nontumorigenic cell cultures.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Adenocarcinoma; Animals; Ascites; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Escherichia coli; Female; Kidney; Liver; Lung; Lymphoma, Non-Hodgkin; Male; Methylation; Methylcholanthrene; Mice; Neoplasm Transplantation; Neoplasms, Experimental; RNA, Bacterial; RNA, Neoplasm; RNA, Transfer; Transferases

1971
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine

1970
Altered transfer RNA methylase patterns in Marek's disease tumors.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Cell-Free System; Chickens; Escherichia coli; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Lung; Methylation; Methyltransferases; Myocardium; Neoplasms; Neoplasms, Experimental; Nucleosides; Oncogenic Viruses; Poultry Diseases; RNA, Neoplasm; RNA, Transfer; Spleen; Transferases; Viruses, Unclassified

1971
Initiation of malignant transformation and the significance of changes in transfer RNA methylase enzymes.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Female; Kidney; Kidney Neoplasms; Male; Methylation; Methyltransferases; Mice; Neoplasms; Ovarian Neoplasms; Ovary; Prostate; Prostatic Neoplasms; RNA, Transfer; Transferases

1971
Reversal of malignant transformation by tumor DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 67, Issue:4

    Topics: Animals; Carcinoma 256, Walker; Cell Transformation, Neoplastic; Culture Techniques; Depression, Chemical; DNA, Neoplasm; Methylation; Rats; RNA, Transfer; Transferases

1970
Transfer RNA and transfer RNA methylation in growing and "resting" adult and embryonic tissues and in various oncogenic systems.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cell-Free System; DNA; DNA, Neoplasm; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Lymphocytes; Methylation; Methyltransferases; Mice; Mitosis; Oncogenic Viruses; RNA, Transfer; Transferases

1971
Transfer RNA's in human leukemia.
    Journal of cellular physiology, 1969, Volume: 74, Issue:2

    Topics: Amino Acid Sequence; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chromatography; Humans; Leucine; Leukemia; Lymphocyte Activation; Lymphocytes; Methylation; RNA, Neoplasm; RNA, Transfer; Time Factors; Tyrosine

1969
Comparison of methyl-labeled tRNA in a neoplastic cell line with a paired non-neoplastic control.
    Experimental and molecular pathology, 1970, Volume: 13, Issue:2

    Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chemistry Techniques, Analytical; Chromatography; Culture Techniques; Embryo, Mammalian; Methionine; Methylation; Mice; Neoplasms, Experimental; RNA, Transfer; Tritium

1970
In vitro transfer RNA methylation in paired neoplastic and nonneoplastic cell cultures.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carbon Isotopes; Cell Differentiation; Cell Transformation, Neoplastic; Cell-Free System; Chromatography; Culture Techniques; Methylation; Mice; Neoplasms, Experimental; Nucleic Acids; Nucleotides; RNA, Neoplasm; RNA, Transfer; Transferases; Tritium

1971
The regulation of transfer RNA methylation in normal and neoplastic mammary cells.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carbon Isotopes; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; Insulin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Methyltransferases; Mice; Prolactin; Protein Biosynthesis; RNA; RNA, Neoplasm; RNA, Transfer; Suppression, Genetic; Time Factors; Transferases

1971