Page last updated: 2024-08-18

isomethyleugenol and Carcinoma, Hepatocellular

isomethyleugenol has been researched along with Carcinoma, Hepatocellular in 261 studies

Research

Studies (261)

TimeframeStudies, this research(%)All Research%
pre-199070 (26.82)18.7374
1990's25 (9.58)18.2507
2000's29 (11.11)29.6817
2010's70 (26.82)24.3611
2020's67 (25.67)2.80

Authors

AuthorsStudies
Chen, B; Huang, P; Huang, X; Li, L; Qiu, Z1
Deng, M; Fang, L; Guo, RP; Li, SH; Mei, J; Wei, W; Zhao, RC; Zou, JW1
Chen, J; He, J; Jiang, Z; Liu, F; Wu, F; Wu, J; Yang, Y1
Fan, Z; Han, H; Liu, G; Liu, P; Liu, Q; Liu, R; Shu, M; Wang, J; Xu, L; Yan, Z; Yang, G; Zhang, W1
Chen, S; Guo, J; He, AR; Jia, M; Jin, J; Li, X; Lin, L; Meng, D; Wang, Z; Wu, H; Zhi, X; Zhou, P1
Chen, J; Liu, T; Tang, H; Zhang, Q1
Lee, JM; Park, SC1
Cai, X; Chen, Y; Ge, J; Ling, Z; Lv, Z; Man, D; Wu, J; Xie, H; Xu, Y; Yu, C; Zhang, D; Zhang, Y; Zheng, S; Zhou, L1
Li, SN; Lu, W; Lv, HC; Lv, YY; Wang, G; Yue, XF; Zhang, XH1
Chen, Y; Han, P; Lei, Y; Liu, J; Liu, M; Tian, D; Wang, H; Wang, M; Wang, S; Yan, W1
Chi, G; Cui, J; He, Y; Li, X; Pang, H; Pei, J; Qu, G; Wu, D1
He, C; Tong, C; Wang, W1
Yao, S; Yin, T; Zhao, L1
Shen, S; Xue, C; Zhao, M1
Cao, Y; Geng, C; He, G; Liu, S; Pan, H; Wu, S1
Duan, Y; Jiang, S; Jing, W; Li, X; Lv, S; Peng, R1
Gu, J; Kong, Y; Wang, Y; Wei, W; Wu, Y; Yang, Q; Zhou, D; Zhou, W1
Li, X; Yan, J; Zhang, HL1
Dai, D; Guo, Y; Wei, Q; Yang, W; Zhang, C; Zhang, W1
Chen, C; Fang, Y; Huang, H; Li, C; Li, N; Miao, Y; Wang, H; Wei, B; Xiao, Z; Xie, J; Zeng, Z; Zhang, ED1
Feng, Y; Han, J; Hu, X; Liu, X; Meng, F; Wang, L; Zhang, Y1
Cao, X; Cheng, Y; Kuang, Y; Li, H; Wang, J; Wang, Y1
Chen, G; Chen, P; Fan, X; Jin, S; Li, D; Lin, H; Liu, X; Shi, Z; Yang, J; Zhang, Y1
Charidemou, E; Kirmizis, A; Koufaris, C; Louca, M; Rubio-Tomás, T1
Cheng, C; Gao, J; Hu, M; Xu, S; Zhang, J; Zheng, W1
Chen, HN; Dai, L; Dong, L; Fu, S; Huang, C; Luo, L; Nice, EC; Peng, Y; Shen, G; Wang, K; Wang, M; Wang, Z; Wei, X; Wu, X1
Bonney, GK; Chow, EK; Chow, PKH; Dan, YY; Goh, BKP; Hooi, L; Jha, S; Kam, JH; Kow, AWC; Lim, JJ; Rajagopalan, D; Rashid, MBMA; Syariff, IQC; Tan, ZM; Thng, DKH; Toh, CCM; Toh, TB; Zhou, L1
Cui, B; Liu, H; Song, Y; Wei, D; Yan, Z; Yin, H1
He, W; Li, B; Li, K; Liao, Y; Lin, Z; Niu, Y; Qiu, J; Qiu, Z; Shi, Y; Wang, C; Wang, G; Yang, Z; Yuan, Y; Zhong, C; Zuo, D1
Al-Moghrabi, N; Al-Showimi, M; Al-Yousef, N; AlOtai, L1
Han, Y; Shang, Y; Tian, S; Yang, L; Zhang, M; Zheng, X; Zhou, X1
Ding, H; Sun, GF1
Cong, P; Huang, X; Liu, Q; Tian, L; Wu, H; Wu, T; Xiong, L; Zhang, H; Zhang, Q; Zhang, X; Zheng, Y1
Ai, J; Deng, W; Huang, Z; Jiang, H; Li, M; Wu, Z; Yan, L; Zhang, L; Zhang, W; Zhou, Z1
Chen, M; Guo, H; Huang, J; Liu, M; Liu, Z; Wang, F; Xia, N; Xiao, B; Zhu, Y1
Chen, Z; Gao, WQ; Hao, W; Tang, J; Xu, H; Yang, R1
Cui, Y; Dai, M; Hu, Y; Kong, W; Wang, X; Wu, H; Wu, J; Yu, B; Yu, X; Zhang, H; Zheng, Y1
Chan, LH; Che, N; Hoo, RLC; Khong, PL; Lee, TK; Lo, CM; Ma, S; Man, K; Ng, KY; Richard, S; Tan, KV; Wong, TL; Zhou, L1
Chen, N; Gong, X; Li, J1
Chen, SL; He, YF; Liu, LL; Lu, SX; Wang, CH; Yang, X; Yun, JP; Zhang, CZ1
Chen, Q; Wan, C; Xiong, J; Xu, J; Zhang, F; Zhang, S1
Feng, M; He, C; Hou, J; Hu, B; Huang, X; Liu, J; Lu, Z; Shen, B; Smyth, MJ; Sun, B; Wang, J; Xia, Q; Zhang, H; Zhao, Z; Zhou, J1
Das, C; Gadad, SS; Klein, BJ; Kutateladze, TG; Mondal, P; Roy, S; Sen, S; Tiwary, N1
He, C; Huang, Y; Liang, H; Peng, F1
Fang, J; Li, F; Li, Z; Peng, Y; Zhou, J1
Ao, J; Chen, H; Chen, J; Dai, S; Lin, Z; Ni, X; Shi, K; Sun, H; Wu, B; Zheng, C1
Gao, L; Ge, Y; Gong, Y; He, Y; Liang, X; Lin, Q; Ma, C; Song, H; Song, X; Tan, S; Wang, T; Wang, Z; Wu, Z; Xu, L; Yu, X; Yuan, D; Yue, X1
Dai, C; Ding, H; Jia, C; Su, Y; Zhang, X1
Fang, Z; Liu, Z; Mao, J; Miao, QR; Wang, K; Wang, Q; Ye, M1
He, X; Hou, B; Huang, K; Huang, S; Ji, F; Ma, Z; Ruan, S; Zhang, C; Zhou, Z; Zhuang, H1
Bu, X; Chen, D; Chen, L; Chen, X; Cheng, C; He, W; Liang, H; Lin, Z; Niu, Y; Sun, L; Wan, A; Wan, G; Zhan, S; Zhang, X1
Fan, H; Li, Y; Lu, T; Mao, Y; Qian, Y; Sun, R; Yu, S; Zhang, Z; Zheng, C1
Chen, H; Fang, Q1
Cao, Y; Ge, J; Hu, G; Shao, J; Xie, P; Yan, C1
Chen, P; Dai, X; Tao, L; Wu, X; Zhang, X1
Hu, DD; Liao, LE; Zheng, Y1
Alaggio, R; Alisi, A; Castellano, A; D'Oria, V; De Stefanis, C; Francalanci, P; Giovannoni, I; Grimaldi, C; Romito, I1
Chang, Z; Li, Z; Liu, Y; Lu, X; Luo, C; Qiao, K; Sun, T; Xu, Z; Yang, C; Zhang, C; Zhang, H1
Guo, Z; Jin, C; Li, Y; Shao, J; Su, Y; Wang, S; Wang, X; Zhang, F; Zhang, Z; Zheng, S1
Chen, X; Gao, T; He, B; Li, C; Liu, X; Pan, B; Pan, Y; Qin, J; Sun, H; Wang, S; Xu, M; Xu, T; Xu, X; Zeng, K1
Chan, LH; Che, N; Huen, MS; Kau, PW; Lee, TK; Ma, S; Ng, KY; Tong, M; Wong, TL; Yun, JP1
Chen, K; Li, J; Liu, J; Yu, A; Zhang, X; Zhang, Z1
Hayashi, M; Inokawa, Y; Kanda, M; Kandimalla, R; Kodera, Y; Koike, M; Nakagawa, N; Nakayama, G; Sonohara, F; Sunagawa, Y; Takami, H; Tanaka, C; Tanaka, K; Yamada, S1
Chen, LM; Fan, YC; Fang, Y; Gao, S; Liu, HH; Wang, K; Xiang, L; Yuan, XD1
Arumugam, T; Chuturgoon, AA; Ghazi, T1
Gao, Y; Guo, B; Guo, C; Huang, C; Liu, L; Qin, Y; Tong, D; Wang, L; Wang, X; Yang, J; Yang, Y; Zhang, J; Zhao, L1
Cui, H; Lin, Y; Wang, L; Wang, Y; Yao, Y1
Li, ZP; Tian, NN; Zhang, FW; Zhang, JF; Zheng, YB1
Huang, P; Li, W; Lin, L; Peng, Y; Xu, J; Yan, Y; Ye, H; Zhang, H; Zhang, R; Zheng, Z1
Chen, YT; Chu, XY; Xiang, D; Zhao, XY1
Cai, J; Xu, J; Zhou, M1
Li, B; Qiu, J; Yuan, Y1
Du, Z; Gao, Y; Luo, Y; Wang, N; Wang, P; Wu, G; Yang, B; Zhang, Y; Zhu, Z1
Chen, T; Cui, M; Cui, Y; Ge, C; Huo, Q; Li, H; Li, J; Sun, J; Tian, H; Xie, H; Yao, M; Zhao, F1
Chen, K; He, J; Huang, Y; Li, B; Liu, J; Liu, Q; Liu, Z; Qi, J; Qin, Y; Wei, L; Yu, X; Zhao, R1
Jensen, ON; Kempf, SJ; Rogowska-Wrzesinska, A; Schwämmle, V; Tvardovskiy, A1
Adams, A; Cox, J; Kumer, S; Li, Z; O'Neil, M; Roberts, B; Schmitt, T; Tikhanovich, I; Vittal, A; Weinman, SA; Zhao, J1
Feng, B; Li, C; Su, Z; Sun, C; Tang, L; Zheng, G; Zhu, Y1
Beck, S; Tanić, M1
Borkin, D; Cierpicki, T; Grembecka, J; Kempinska, K; Klossowski, S; Malik, B; Miao, H; Shukla, S; Wang, J1
Li, T; Liu, Y; Shi, Y; Wang, L; Wang, T; Wang, X; Wang, Y; Yang, Y1
Bai, J; Chen, S; Gao, J; Li, H; Pu, J; Shuai, X; Tao, K; Wang, G; Wang, J; Wu, K; Yin, Y1
Lai, PBS; Lam, EKY; Lau, CPY; Li, SSK; Lui, VWY; Ng, PKS; Ng, YK; Tsui, SKW; Yeo, W1
Ding, LH; Gao, SB; Jin, GH; Liu, JY; Ni, GY; Qiu, H; Wang, HM; Xu, B; Ye, J; Zhang, L; Zheng, QF; Zhu, LY1
Chen, LY; Fan, YC; Gao, S; Li, F; Qiao, CY; Wang, K1
Cheng, ASL; Feng, H; Feng, J; Gao, Y; Huang, L; Khan, H; Li, M; Mok, MTS; Song, H; Sun, X; Yu, Q; Yu, Z; Zhu, X1
Jeng, YM; Jhuang, YL; Lien, HC; Yuan, RH1
Hamada, M; Zhang, Y1
Claret, FX; Guo, H; Jing, L; Li, W; Liang, X; Nan, K; Ruan, Z; Tian, T; Wang, X; Wang, Y; Xiang, L; Yu, S1
Chan, SL; Chen, GG; Chen, Y; Lai, PBS; Li, CH; Shao, S; Wong, CH; Xu, F1
Chen, L; Jan, YJ; Jiang, SS; Ko, BS; Liang, SM; Liou, JY; Lu, YJ; Shyue, SK; Wu, YJ1
Brock, MV; Guo, M; Herman, JG; Licchesi, JD; Liu, X; Pei, X; Yang, Y; Yue, W; Zhang, X1
Cheng, EH; Dong, Y; Hsieh, JJ; Liu, H; Sasagawa, S; Takeda, S; Trainor, PA1
Shan, Y; Wu, Q; Zhang, L; Zhang, S; Zhang, Y; Zhou, Y1
Aktas, S; Bilezikci, B; Ozer, O; Sahin, FI1
Aburatani, H; Fukayama, M; Hayashi, A; Ishikawa, S; Kimura, H; Kokudo, N; Morikawa, T; Nagae, G; Nishi, A; Sakamoto, Y; Shibahara, J; Yamauchi, N1
Chen, C; Liu, Y; Wang, K; Wu, W; Xu, X; Zhang, L1
Doki, Y; Eguchi, H; Hama, N; Ishii, H; Kawamoto, K; Kobayashi, S; Koga, C; Konno, M; Mori, M; Nagano, H; Tomimaru, Y; Umeshita, K; Wada, H1
Ding, LH; Feng, ZJ; Gao, SB; Hua, X; Jin, GH; Li, SH; Wei, J; Xu, B; Yin, ZY; Zhang, L; Zheng, QF; Zheng, QL1
Gao, SB; Jin, GH; Li, KL; Lin, X; Pan, CB; Xu, B; Xue, LX; Zhao, Y; Zheng, QF; Zheng, QL1
Fu, WM; Jiang, HQ; Liang, WC; Qi, W; Wan, DC; Wang, WM; Wang, Y; Wang, YB; Waye, MM; Xiao, LJ; Zhang, JF1
Chang, JG; Hung, SY; Lin, HH; Yeh, KT1
Gao, N; Wu, J; Xi, Q; Ye, W; Zhang, B; Zhang, X1
Chalepakis, G; Hatzis, P; Moulos, P; Nikolaou, KC; Oda, H; Reinberg, D; Talianidis, I1
Anan, K; Arita, K; Hino, S; Kanai, Y; Matsumori, H; Nagaoka, K; Nakao, M; Ojima, H; Sakamoto, A; Takase, R1
Abiko, R; Fukumoto, M; Kishida, A; Kuwahara, Y; Ohkubo, Y; Saito, Y; Yamamoto, F; Yamamoto, Y1
Fujita, Y; Hamamoto, Y; Hashimoto, N; Hazama, S; Iida, M; Iizuka, N; Kanekiyo, S; Maeda, Y; Oka, M; Sakamoto, K; Tamesa, T; Tokuhisa, Y; Tokumitsu, Y; Tsunedomi, R; Yoshino, S1
Fujii, T; Fujiwara, M; Hayashi, M; Hishida, M; Inokawa, Y; Iwata, N; Kanda, M; Kobayashi, D; Kodera, Y; Koike, M; Nakayama, G; Nishikawa, Y; Nomoto, S; Sugimoto, H; Takano, N; Tanaka, C; Yamada, S1
Choi, SW; Conci, S; Corrocher, R; Friso, S; Guarini, P; Guglielmi, A; Moruzzi, S; Olivieri, O; Pattini, P; Ruzzenente, A; Tammen, SA; Udali, S1
Li, WM; Liu, HR1
Chiummiento, L; Convertini, P; Iacobazzi, V; Infantino, V; Lupattelli, P; Tramutola, F1
Fan, YC; Gao, S; Ji, XF; Jia, YB; Li, F; Li, XY; Liu, C; Sun, FK; Sun, Q; Wang, K; Wang, LY; Zhao, J1
Liu, XJ; Wang, DY; Zhu, HG; Zhu, R; Zou, LP1
Li, Z; Sun, HG; Sun, Y; Wang, FQ; Wang, XM; Xie, CR; Yin, ZY; Zhang, S; Zhao, WX1
Liu, Y; Xiong, L; Xiong, Q1
Chan, AW; Chan, MT; Cheng, AS; Kang, W; Lai, PB; Lau, SS; Lee, SD; Lee, TL; Lee, YY; Li, MS; Li, X; Lo, KW; To, KF; Tong, JH; Tsang, DP; Wang, H; Wong, N; Wu, F; Wu, WK; Xiong, L; Xu, G; Yang, W; Yang, Y; Yip, KY; Yu, DY; Yu, J; Yu, Z1
Feng, B; He, SM; LIu, Y; Zheng, GJ; Zhu, Y; Zhu, YZ1
Cai, MY; Chen, JW; Chen, WH; Guan, XY; Jiang, LJ; Jin, XH; Li, CP; Liao, YJ; Mai, SJ; Pei, XQ; Wang, FW; Xie, D; Zeng, MS1
Du, Y; Fan, Z; He, L; Huang, G; Liu, B; Wang, Y; Wu, J; Ye, B; Zhu, P1
An, SH; Bai, SS; Liu, L; Wang, DY; Wang, ZJ; Wu, KX; Zhu, R1
Bécsi, B; Darula, Z; Erdődi, F; Horváth, D; Iván, J; Lontay, B; Medzihradszky, KF; Sipos, A; Tamás, I1
Kim, S; Kim, YJ; Lee, SM; Park, SH1
Bian, XL; Chen, HZ; Chen, QT; Chien, KY; Li, YP; Sun, XY; Wang, WJ; Wang, XM; Wu, Q; Yang, PB; Zhang, FN; Zhang, JY; Zhang, S; Zhao, WX; Zheng, Y1
Chen, J; Liao, N; Sun, L; Zhang, R; Zhang, Y; Zhong, J1
Ebina, M; Funayama, R; Igarashi, K; Itoh-Nakadai, A; Katoh, Y; Matsumoto, M; Nakayama, K; Sato, M; Sato, Y; Unno, M1
Imai, K; Maruyama, R; Nojima, M; Omata, M; Sasaki, S; Shinomura, Y; Suzuki, H; Takagi, H; Tokino, T; Toyota, M; Yamamoto, H1
Cho, JW; Gu, JM; Jung, G; Kim, HS; Kim, MS; Lim, SO; Park, CK; Park, YM; Park, YN1
Bagnyukova, TV; Beland, FA; Muskhelishvili, L; Pogribny, IP; Ross, SA; Tryndyak, VP1
Beezhold, KJ; Bhatia, D; Castranova, V; Chang, Q; Chen, F; Chen, J; Shi, X; Zhang, Y; Zhao, H1
Agirre, E; Alló, M; Buggiano, V; Chabot, B; de la Mata, M; Elela, SA; Eyras, E; Fededa, JP; Klinck, R; Kornblihtt, AR; Petrillo, E; Plass, M; Schor, I1
Braunschweig, T; Büttner, R; Ellinger, J; Gütgemann, I; Höller, T; Koch, LK; Kremmer, E; Lüscher, B; Magerl, C1
Fujita, Y; Hamamoto, Y; Iida, M; Iizuka, N; Ishitsuka, H; Kimura, N; Miura, T; Moribe, T; Oka, M; Sakaida, I; Sakamoto, K; Tamatsukuri, S; Tamesa, T; Tokuhisa, Y; Tsunedomi, R; Tsutsui, M1
Bai, T; Du, Z; Gao, YT; Lou, C; Song, WQ; Wang, YJ; Yang, B; Zhang, SG1
Jung, G; Lim, SO; Min, JY1
Chen, SY; Chen, YM; Chiang, EP; Tang, FY; Wang, YC1
Bardag-Gorce, F; Buslon, V; French, BA; French, SW; Li, J; Oliva, J; Zhong, J1
Lu, HJ; Nie, AY; Xie, LQ; Yan, GQ; Yang, PY; Yang, SJ; Yao, J; Zhang, L1
Cai, J; Chen, D; Chen, J; Chen, L; Chen, T; Feng, L; Guo, L; He, Y; Ji, Y; Jin, TG; Li, S; Liang, C; Lin, X; Liu, Y; Lu, X; Mei, J; Ning, Z; Pan, D; Pan, S; Peng, Z; Ren, S; Ren, Y; Rong, Y; Shan, S; She, J; Tang, G; Wang, Z; Wong, JC; Wu, X; Xu, C; Zhang, C; Zhang, M; Zhang, N; Zhang, W; Zhang, X; Zhang, Z; Zhao, R; Zhao, W; Zhou, M1
Avila, MA; Berasain, C; Corrales, FJ; Elizalde, M; Garcia-Irigoyen, O; Latasa, MU; Nicou, A; Perugorría, MJ; Prieto, J; Recio, JA; Salis, F; Urtasun, R1
Fan, YC; Gao, S; Sun, FK; Sun, Q; Wang, K; Zhang, F; Zhao, J; Zhao, ZH1
Fan, H; Kong, J; Wang, W; Xu, L; Yang, P1
Ghoshal, K; Jacob, ST; Majumder, S1
Banerjee, R; Oltean, S1
Chen, GQ; Chen, Z; Jing, Y; Styblo, M; Walton, F; Waxman, S; Weinberg, R; Zhou, L1
Hinderlich, S; Oetke, C; Pawlita, M; Reutter, W1
Beljord, C; Carrié, A; Chalas, C; Chaussade, S; Chelly, J; Couvert, P; Gicquel, C; Kerjean, A; Mallet, V; Marchio, A; Poirier, K; Sarli, D; Terris, B; Tissier, F1
Duong, FH; Filipowicz, M; Heim, MH; La Monica, N; Tripodi, M1
Fujie, H; Kimura, S; Koike, K; Makuuchi, M; Miyoshi, H; Moriya, K; Shintani, Y; Tsutsumi, T1
Ohkawa, K1
Barve, S; Chen, T; Kang, YJ; McClain, CJ; Song, Z; Uriarte, S; Wang, L; Zhou, Z1
Galli, C; Ghezzi, S; Priori, I; Risé, P1
Du, Z; Gao, YT; Song, WQ; Yang, B; Zhao, L1
Chovolou, Y; Kampkötter, A; Michels, G; Mohamed, GA; Proksch, P; Wätjen, W; Weber, N1
Chen, JX; Chen, YP; Deng, CS; Zhang, YC1
Hou, J; Li, H; Li, J; Liew, CT; Yin, D; Zhang, C; Zhang, J; Zhang, Q; Zhang, T; Zhou, G1
Hermes, M; Kloor, D; Osswald, H1
Krcmárr, P; Machala, M; Marvanová, S; Milcová, A; Nováková, Z; Penccíková, K; Topinka, J; Trilecová, L; Vondrácek, J1
Becker, FF; Lapeyre, JN; Walker, MS1
Imazeki, F; Kato, N; Kawai, S; Ohto, M; Omata, M; Shiina, S; Yokosuka, O1
el Yaagoubi, M; Siest, G; Visvikis, A; Wellman, M1
Chen, DS; Chu, JS; Hsu, HC; Lai, PL; Lee, PH; Peng, SY; Tsung, PT1
Bai, S; Burk, RD; Pietrangelo, A; Schoenfeld, A1
Båvenholm, P; Eriksson, P; Hamsten, A; Kallin, B; van 't Hooft, FM1
Aihara, T; Imaoka, S; Nakano, H; Noguchi, S; Sasaki, Y1
Chang, KJ; Liu, YC; Liu, YW1
Arthur, G; Badiani, K; Lu, X1
Cao, Y; Gu, JR; He, L; Li, D; Wang, NJ1
Adlercreutz, H; Carson, M; Loukovaara, M; Palotie, A1
Aoki, Y; Choi, EK; Fujimura, S; Fukuda, Y; Kim, YS; Nakao, K; Nata, M; Nishida, N; Okumoto, T; Ono, T; Sagisaka, K; Uyeno, S; Yoshimoto, T1
Goldman, ND; Li, SP1
Aunis, D; Sawaya, BE; Schaeffer, E1
Asakura, H; Ichida, T; Matsuda, Y; Matsuzawa, J; Sugimura, K1
Herman, JG1
Hirohashi, S; Hui, AM; Kanai, Y; Sakamoto, M; Sun, L; Tsuda, H; Ushijima, S1
Jin, M; Jung, HJ; Kim, CG; Kim, H; Kim, NG; Park, C; Park, JH; Piao, Z; Shin, EC1
Johnson, PJ; Lai, PB; Lo, YM; Wong, IH1
Avila, MA; Berasain, C; Caballería, J; Corrales, FJ; Lu, SC; Martín-Duce, A; Mato, JM; Prieto, J; Rodés, J; Torres, L; Yang, H1
Enomoto, T; Fujita, M; Haba, T; Hamada, T; Hirohashi, K; Kinoshita, H; Kubo, S; Okuda, T; Wakasa, K1
Konishi, Y; Nakae, D; Tsujiuchi, T1
Aoyagi, Y; Kawai, H; Suda, T1
Bakker, J; Lin, X; Nelson, WG1
Herath, NI; Kew, MC; Leggett, BA; MacDonald, GA; Powell, LW; Walsh, MD; Young, J1
Hurlbert, RB; Liau, MC2
Hochberg, AA; Morris, HP; Stratman, FW; Zahlten, RN1
Hilliard, JK; Sneider, TW1
Desrosiers, RC; Friderici, KH; Rottman, FM1
Kerr, SJ3
Busch, H; Nazar, RN; Sitz, TO1
Friderici, K; Kaehler, M; Rottman, F1
Hurlbert, RB; Knight, CA; Liau, MC; Lin, GW1
Borek, E; Kuchino, Y1
Lee, JK; Tam, JW; Tsai, MJ; Tsai, SY1
Buckley, JD1
Cronin, GM; Lyn-Cook, BD; Poirier, LA; Zapisek, WF1
Le Bouc, Y; Noguiez, P; Schneid, H; Seurin, D1
Axelson, M; Everson, GT; Mörk, B1
Goodman, JI; Vorce, RL1
Beitel, G; Foster, R; Gedamu, L; Jahroudi, N; Price-Haughey, J1
Asakura, H; Kamimura, T; Ogata, N1
Huang, ZM; Nonaka, M1
Aiba, N; Inoue, K; Nambu, S; Sasaki, H1
Campion, B; Léger, D; Montreuil, J; Spik, G; Wieruszeski, JM1
Higashi, T; Iwaki, Y; Kobata, A; Sakamoto, Y; Takamisawa, I; Tateishi, N; Totani, K; Yamashita, K1
Katznelson, R; Kulka, RG1
Endo, Y; Hayashida, N; Kaneko, Y; Nakayama, T; Oda, T; Oka, H; Shibuya, M; Toda, G1
Inoue, K; Nambu, S; Saski, H1
Brière, N1
Adamson, RH; Gallo, RC; O'Gara, RW; Waalkes, TP2
Kroes, R; Weisburger, JH; Williams, GM1
Lichtenstein, AV; Piker, EG; Shapot, VS1
Hancock, RL3
Behki, RM; Geil, JH; Morgan, WS; Stenger, RJ1
Busch, H; Nakamura, T; Prestayko, AW1
Dickie, MM; Hancock, RL1
Bilik, E; Sheid, B1
Potter, VR; Sneider, TW1
Chang, LO; Looney, WB; Morris, HP1
Busch, H; Hodnett, JL; Moriyama, Y; Prestayko, AW1
Craddock, VM1
Busch, H; Choi, YC1
Elford, HL; Freese, M; Morris, HP; Passamani, E1
Hancock, RL; Turner, G1
Flatt, NC; Hurlbert, RB; Liau, MC1
Hakomori, S; Siddiqui, B1
Borek, E; Kerr, SJ; Sharma, OK1
Rennert, OM1
Sneider, TW1
Byvoet, P2
Gonano, F; Pirrò, G1
Lee, HW; Morris, HP; Paik, WK1
Shearer, RW; Smuckler, EA1
Glover, EL; Reuber, MD; Stromberg, K1
Inose, M; Iwanami, Y; Miyata, S1
Sneider, T1
Dixon, B; Fiala, AE; Fiala, S1
Craft, K; Glick, M; Orlando, RA; Wissler, RW1
Gottlieb, LS; Hegsted, DM; Iseri, OA; Vitale, JJ1
Daoust, R1
Hunt, JB; Hurlbert, RB; Liau, MC; Smith, DW1
Borchert, P; Miller, EC; Miller, JA; Shires, TK1
Bayev, AA; Shershneva, LP; Venkstern, TV2
Pitot, HC; Wilkinson, DS1
Sharma, OK1
Chia, LL; Morris, HP; Randerath, E; Randerath, K2
Nau, F1
Abakumova, OIu; Gorbacheva, LB; Kukushkina, GV; Kutsenko, NG; Lerman, MI1
Ho, Y; Lin, HJ1
Den Engelse, L1
Howard, E; Tidwell, T1
Desrosiers, R; Friderici, K; Rottman, F1
Inose, M; Iwanami, Y1

Reviews

8 review(s) available for isomethyleugenol and Carcinoma, Hepatocellular

ArticleYear
Roles of M
    Current gene therapy, 2022, Volume: 22, Issue:1

    Topics: Adenosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Methyltransferases

2022
Role of m6A RNA methylation in the development of hepatitis B virus-associated hepatocellular carcinoma.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:11

    Topics: Carcinoma, Hepatocellular; Hepatitis B; Hepatitis B virus; Humans; Liver Cirrhosis; Liver Neoplasms; Methylation; RNA; Tumor Microenvironment

2022
Histone methylation in pre-cancerous liver diseases and hepatocellular carcinoma: recent overview.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:6

    Topics: Adult; Carcinoma, Hepatocellular; Histones; Humans; Liver Neoplasms; Methylation

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
N6-methyladenosine RNA methylation in liver diseases: from mechanism to treatment.
    Journal of gastroenterology, 2023, Volume: 58, Issue:8

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; RNA

2023
Upregulation of lncRNA NIFK-AS1 in hepatocellular carcinoma by m
    Human cell, 2021, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Methylation; Methyltransferases; Molecular Targeted Therapy; Neoplasm Invasiveness; Nuclear Proteins; RNA, Long Noncoding; Sorafenib; Up-Regulation

2021
[Oncogene c-myc].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6

    Topics: Animals; Carcinoma, Hepatocellular; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Liver Neoplasms; Methylation

2001
[Loss of heterozygosity in hepatocarcinogenesis].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6

    Topics: Allelic Imbalance; Carcinoma, Hepatocellular; Chromosomes; DNA Replication; Genome, Human; Humans; Liver Neoplasms; Loss of Heterozygosity; Methylation

2001

Trials

2 trial(s) available for isomethyleugenol and Carcinoma, Hepatocellular

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-14, Volume: 92, Issue:6

    Topics: Adult; Alleles; Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Deoxyribonuclease I; DNA-Binding Proteins; Gene Expression; Genotype; Humans; Liver Neoplasms; Male; Methylation; Molecular Sequence Data; Myocardial Infarction; Odds Ratio; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Promoter Regions, Genetic; Reference Values; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1995

Other Studies

252 other study(ies) available for isomethyleugenol and Carcinoma, Hepatocellular

ArticleYear
m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma.
    Aging, 2021, 08-30, Volume: 13, Issue:16

    Topics: Algorithms; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cohort Studies; CTLA-4 Antigen; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immunity; Immunotherapy; Liver; Liver Neoplasms; Methylation; Methyltransferases; Principal Component Analysis; Programmed Cell Death 1 Receptor; RNA; Tumor Microenvironment

2021
Expression pattern and prognostic value of N6-methyladenosine RNA methylation key regulators in hepatocellular carcinoma.
    Mutagenesis, 2021, 10-06, Volume: 36, Issue:5

    Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cluster Analysis; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation; Prognosis; Protein Interaction Mapping; Protein Interaction Maps; RNA; ROC Curve; Transcriptome

2021
    Stem cells and development, 2021, Volume: 30, Issue:22

    Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Methylation; Mice; Neoplastic Stem Cells; Phenotype; RNA; RNA Stability; RNA-Binding Proteins

2021
Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2-dependent silencing of SLC7A11.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:21

    Topics: Amino Acid Transport System y+; Carcinoma, Hepatocellular; Cell Line, Tumor; Ectopic Gene Expression; Ferroptosis; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxidation; Liver Neoplasms; Methylation; Methyltransferases; Models, Biological; Prognosis; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Messenger

2021
Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development.
    Cellular and molecular gastroenterology and hepatology, 2022, Volume: 13, Issue:3

    Topics: Animals; Autophagy; Carcinogenesis; Carcinoma, Hepatocellular; Carrier Proteins; Histone-Lysine N-Methyltransferase; Liver Neoplasms; Methylation; Mice; Microfilament Proteins; YAP-Signaling Proteins

2022
Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma.
    Genes & genomics, 2022, Volume: 44, Issue:3

    Topics: Carcinoma, Hepatocellular; Enhancer of Zeste Homolog 2 Protein; Glucose; Humans; Liver Neoplasms; Lysine; Methylation; Protein Processing, Post-Translational; Thyroid Hormone Receptors beta

2022
Activation of YAP1 by N6-Methyladenosine-Modified circCPSF6 Drives Malignancy in Hepatocellular Carcinoma.
    Cancer research, 2022, 02-15, Volume: 82, Issue:4

    Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Methylation; Middle Aged; Prognosis; RNA-Binding Proteins; RNA, Circular; YAP-Signaling Proteins

2022
Mechanism of miR-424-5p promoter methylation in promoting epithelial-mesenchymal transition of hepatocellular carcinoma cells.
    The Kaohsiung journal of medical sciences, 2022, Volume: 38, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Kinesins; Liver Neoplasms; Methylation; Mice; MicroRNAs

2022
Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A.
    Clinical and translational medicine, 2022, Volume: 12, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; China; Disease Models, Animal; Glycolysis; Histology; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Methylation; Mice; Protein-Arginine N-Methyltransferases

2022
SMYD5 acts as a potential biomarker for hepatocellular carcinoma.
    Experimental cell research, 2022, 05-15, Volume: 414, Issue:2

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation

2022
m1A methylation modification patterns and metabolic characteristics in hepatocellular carcinoma.
    BMC gastroenterology, 2022, Mar-03, Volume: 22, Issue:1

    Topics: Adenosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Prognosis; RNA Processing, Post-Transcriptional

2022
Comprehensive characterization of m6A methylation and its impact on prognosis, genome instability, and tumor microenvironment in hepatocellular carcinoma.
    BMC medical genomics, 2022, 03-08, Volume: 15, Issue:1

    Topics: Carcinoma, Hepatocellular; Genomic Instability; Humans; Liver Neoplasms; Methylation; Prognosis; Tumor Microenvironment

2022
A Novel m1A-Score Model Correlated With the Immune Microenvironment Predicts Prognosis in Hepatocellular Carcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Prognosis; Tumor Microenvironment

2022
Identification and validation of the N6-methyladenosine RNA methylation regulator ZC3H13 as a novel prognostic marker and potential target for hepatocellular carcinoma.
    International journal of medical sciences, 2022, Volume: 19, Issue:4

    Topics: Adenosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Nuclear Proteins; Prognosis; RNA; RNA-Binding Proteins

2022
Study on the Prognostic Values of TTC36 Correlated with Immune Infiltrates and Its Methylation in Hepatocellular Carcinoma.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Prognosis

2022
m6A regulator-mediated methylation modification highlights immune infiltration patterns for predicting risk in hepatocellular carcinoma.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:7

    Topics: Adenosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; RNA; Tumor Microenvironment

2023
[MicroRNA Methylation in the Diagnosis and Treatment of Hepatocellular Carcinoma].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2022, Volume: 44, Issue:4

    Topics: Carcinoma, Hepatocellular; Gene Expression Regulation; Humans; Liver Neoplasms; Methylation; MicroRNAs

2022
STMN1 as a novel prognostic biomarker in HCC correlating with immune infiltrates and methylation.
    World journal of surgical oncology, 2022, Sep-20, Volume: 20, Issue:1

    Topics: Biomarkers; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Prognosis; Stathmin

2022
m
    Frontiers in immunology, 2022, Volume: 13

    Topics: Carcinoma, Hepatocellular; Epigenesis, Genetic; Humans; Liver Neoplasms; Methylation; Protein Processing, Post-Translational; Tumor Microenvironment

2022
KIAA1429 mediates epithelial mesenchymal transition in sorafenib-resistant hepatocellular carcinoma through m6A methylation modification.
    Cancer medicine, 2023, Volume: 12, Issue:6

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Liver Neoplasms; Methylation; Sorafenib

2023
Identification and development of a novel risk model based on cuproptosis-associated RNA methylation regulators for predicting prognosis and characterizing immune status in hepatocellular carcinoma.
    Hepatology international, 2023, Volume: 17, Issue:1

    Topics: Apoptosis; Carcinoma, Hepatocellular; Copper; Humans; Liver Neoplasms; Methylation; Prognosis; RNA; Tumor Microenvironment

2023
Integrated investigation of the clinical implications and targeted landscape for RNA methylation modifications in hepatocellular carcinoma.
    European journal of medical research, 2023, Jan-27, Volume: 28, Issue:1

    Topics: Carcinoma, Hepatocellular; Epigenesis, Genetic; Humans; Liver Neoplasms; Methylation; MicroRNAs; Prognosis; Tumor Microenvironment

2023
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma.
    Nature communications, 2023, 02-23, Volume: 14, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Humans; Liver Neoplasms; Methylation; Phosphoglycerate Dehydrogenase; Protein-Arginine N-Methyltransferases; Repressor Proteins; Serine

2023
Histone-lysine N-methyltransferase EHMT2 (G9a) inhibition mitigates tumorigenicity in Myc-driven liver cancer.
    Molecular oncology, 2023, Volume: 17, Issue:11

    Topics: Carcinoma, Hepatocellular; Epigenesis, Genetic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Liver Neoplasms; Methylation

2023
Analyzing the Role of Septin9 Gene Methylation in the Diagnosis and Treatment of Primary Liver Cancer in the Elderly.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:4

    Topics: Aged; alpha-Fetoproteins; Bilirubin; Biomarkers, Tumor; Carcinoma, Hepatocellular; gamma-Glutamyltransferase; Humans; Liver Neoplasms; Methylation; Prospective Studies

2023
PRMT3-mediated arginine methylation of IGF2BP1 promotes oxaliplatin resistance in liver cancer.
    Nature communications, 2023, 04-06, Volume: 14, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Methylation; Oxaliplatin; Protein-Arginine N-Methyltransferases

2023
MicroRNA-155-5p, Reduced by Curcumin-Re-Expressed Hypermethylated
    International journal of molecular sciences, 2023, May-19, Volume: 24, Issue:10

    Topics: Biomarkers; BRCA1 Protein; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Curcumin; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation; MicroRNAs

2023
NOP2-mediated m5C methylation of XPD is associated with hepatocellular carcinoma progression.
    Neoplasma, 2023, Volume: 70, Issue:3

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Methyltransferases; Mixed Function Oxygenases; Nuclear Proteins; Proto-Oncogene Proteins; Signal Transduction; tRNA Methyltransferases

2023
Genomic gain/methylation modification/hsa-miR-132-3p increases RRS1 overexpression in liver hepatocellular carcinoma.
    Cancer science, 2023, Volume: 114, Issue:11

    Topics: Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Genomics; Humans; Liver Neoplasms; Methylation; MicroRNAs; RNA-Binding Proteins

2023
Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.
    Journal of translational medicine, 2023, 09-15, Volume: 21, Issue:1

    Topics: Arginine; Carcinoma, Hepatocellular; Ferroptosis; Hepatitis B virus; HSC70 Heat-Shock Proteins; Humans; Liver Neoplasms; Methylation

2023
N6-methyladenosine-modified oncofetal lncRNA MIR4435-2HG contributed to stemness features of hepatocellular carcinoma cells by regulating rRNA 2'-O methylation.
    Cellular & molecular biology letters, 2023, Oct-27, Volume: 28, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation; RNA, Long Noncoding

2023
hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner.
    Journal of translational medicine, 2023, Nov-28, Volume: 21, Issue:1

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Methylation; Mice; Phosphoenolpyruvate Carboxykinase (GTP); RNA; RNA-Binding Proteins; RNA, Guide, CRISPR-Cas Systems; RNA, Messenger

2023
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
    Cancer science, 2019, Volume: 110, Issue:11

    Topics: Acetylation; Animals; Azepines; Cadherins; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histocompatibility Antigens; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Snail Family Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta

2019
CRAF Methylation by PRMT6 Regulates Aerobic Glycolysis-Driven Hepatocarcinogenesis via ERK-Dependent PKM2 Nuclear Relocalization and Activation.
    Hepatology (Baltimore, Md.), 2020, Volume: 71, Issue:4

    Topics: Active Transport, Cell Nucleus; Carcinogenesis; Carcinoma, Hepatocellular; Cell Nucleus; Extracellular Signal-Regulated MAP Kinases; Hep G2 Cells; Humans; Liver Neoplasms; Methylation; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-raf; Pyruvate Kinase; Warburg Effect, Oncologic

2020
Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas.
    Molecular medicine reports, 2019, Volume: 20, Issue:6

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Computational Biology; Databases, Genetic; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genomics; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Prognosis; ROC Curve; Transcriptome

2019
Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways.
    Molecular oncology, 2020, Volume: 14, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Liver Neoplasms; MAP Kinase Signaling System; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Prognosis; raf Kinases; ras Proteins; RNA Interference; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2020
CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway.
    Journal of experimental & clinical cancer research : CR, 2019, Nov-14, Volume: 38, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; CRISPR-Cas Systems; Female; Hep G2 Cells; Heterografts; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Promoter Regions, Genetic; Proto-Oncogene Proteins; Signal Transduction; Wnt Proteins

2019
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma.
    Molecular cancer, 2019, 11-18, Volume: 18, Issue:1

    Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Epigenesis, Genetic; Humans; Inflammation; Liver Neoplasms; Methylation; Mice; Models, Biological; Neovascularization, Pathologic; RNA-Binding Proteins; RNA, Messenger; Transcriptome

2019
TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark.
    Biochemistry, 2020, 02-04, Volume: 59, Issue:4

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Hep G2 Cells; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Models, Molecular; PHD Zinc Fingers; Protein Binding; Transcription Factors

2020
Hepatitis B Virus X Protein-Induced ROR
    BioMed research international, 2019, Volume: 2019

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatitis B; Hepatitis B virus; Humans; Liver Neoplasms; Methylation; Nuclear Receptor Subfamily 1, Group F, Member 3; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2019
Identification of three m6A-related mRNAs signature and risk score for the prognostication of hepatocellular carcinoma.
    Cancer medicine, 2020, Volume: 9, Issue:5

    Topics: Adenosine; Biomarkers, Tumor; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Methyltransferases; Nomograms; Risk Factors; RNA, Messenger; ROC Curve; Suppressor of Cytokine Signaling Proteins; Transaminases

2020
Screening and verification of microRNA promoter methylation sites in hepatocellular carcinoma.
    Journal of cellular biochemistry, 2020, Volume: 121, Issue:7

    Topics: Aged; Algorithms; Area Under Curve; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cluster Analysis; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Methylation; MicroRNAs; Middle Aged; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; Risk; Risk Factors; Software; Up-Regulation

2020
ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation.
    EBioMedicine, 2020, Volume: 53

    Topics: Animals; Carcinoma, Hepatocellular; F-Box Proteins; Female; Hep G2 Cells; Histone Code; Homeodomain Proteins; Humans; Jumonji Domain-Containing Histone Demethylases; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred C57BL; Middle Aged; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factor-3; SOXC Transcription Factors; Transcription Factors

2020
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
    Cellular & molecular biology letters, 2020, Volume: 25

    Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromogranins; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; GTP-Binding Protein alpha Subunits, Gs; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; RNA Interference; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2020
Comparative proteomic analysis of protein methylation provides insight into the resistance of hepatocellular carcinoma to 5-fluorouracil.
    Journal of proteomics, 2020, 05-15, Volume: 219

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; Methylation; Protein Processing, Post-Translational; Proteomics

2020
YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation.
    Oncogene, 2020, Volume: 39, Issue:23

    Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Prognosis; RNA-Binding Proteins; RNA, Messenger; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured

2020
RNA m
    The EMBO journal, 2020, 06-17, Volume: 39, Issue:12

    Topics: Adenosine; Animals; Autophagy; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Forkhead Box Protein O3; HEK293 Cells; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Sorafenib

2020
High methylation levels of histone H3 lysine 9 associated with activation of hypoxia-inducible factor 1α (HIF-1α) predict patients' worse prognosis in human hepatocellular carcinomas.
    Cancer genetics, 2020, Volume: 245

    Topics: Carcinoma, Hepatocellular; Cell Nucleus; Gene Expression Regulation, Neoplastic; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Lysine; Methylation; Prognosis; Retrospective Studies; Survival Analysis; Tissue Array Analysis; Up-Regulation

2020
The significance of m6A RNA methylation regulators in predicting the prognosis and clinical course of HBV-related hepatocellular carcinoma.
    Molecular medicine (Cambridge, Mass.), 2020, 06-17, Volume: 26, Issue:1

    Topics: Adenine; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Gene Expression Profiling; Hepatitis B; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; RNA

2020
PRMT2 accelerates tumorigenesis of hepatocellular carcinoma by activating Bcl2 via histone H3R8 methylation.
    Experimental cell research, 2020, 09-15, Volume: 394, Issue:2

    Topics: Animals; Apoptosis; Arginine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-bcl-2; Up-Regulation

2020
Prognostic Value of an m6A RNA Methylation Regulator-Based Signature in Patients with Hepatocellular Carcinoma.
    BioMed research international, 2020, Volume: 2020

    Topics: Adenosine; Carcinoma, Hepatocellular; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Prognosis; Reproducibility of Results; Risk Factors; RNA, Neoplasm

2020
A Four-Methylated lncRNAs-Based Prognostic Signature for Hepatocellular Carcinoma.
    Genes, 2020, 08-08, Volume: 11, Issue:8

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Computational Biology; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation; Prognosis; Proportional Hazards Models; Reproducibility of Results; RNA Processing, Post-Transcriptional; RNA, Long Noncoding; ROC Curve; Transcriptome

2020
Focal Adhesion Kinase (FAK) Over-Expression and Prognostic Implication in Pediatric Hepatocellular Carcinoma.
    International journal of molecular sciences, 2020, Aug-12, Volume: 21, Issue:16

    Topics: beta Catenin; Carcinoma, Hepatocellular; Cell Nucleus; Child; Enhancer of Zeste Homolog 2 Protein; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Cirrhosis; Liver Neoplasms; Lysine; Male; Methylation; Phosphorylation; Phosphotyrosine; Prognosis; Proliferating Cell Nuclear Antigen; Tumor Burden; Up-Regulation

2020
RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway.
    Angiogenesis, 2021, Volume: 24, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Silencing; Hippo Signaling Pathway; Humans; Liver Neoplasms; Methylation; Methyltransferases; Mice, Inbred BALB C; Mice, Nude; Molecular Mimicry; Prognosis; Protein Biosynthesis; Protein Serine-Threonine Kinases; RNA; RNA, Messenger; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins

2021
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26.
    Cell death & disease, 2020, 10-11, Volume: 11, Issue:10

    Topics: Amino Acid Transport Systems; Animals; Calcium-Binding Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cellular Senescence; Coordination Complexes; Copper; Hep G2 Cells; Humans; Liver Neoplasms; Methionine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Telomerase; Transfection; Xenograft Model Antitumor Assays

2020
Analysis of METTL3 and METTL14 in hepatocellular carcinoma.
    Aging, 2020, 11-06, Volume: 12, Issue:21

    Topics: Adenosine; Carcinoma, Hepatocellular; Databases, Genetic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Liver Neoplasms; Methylation; Methyltransferases; RNA Stability; RNA, Messenger; Signal Transduction; Transcriptome

2020
PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.
    Cancer letters, 2021, 03-31, Volume: 501

    Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Hep G2 Cells; HSC70 Heat-Shock Proteins; Humans; Liver Neoplasms; Male; Methylation; Mice; Neoplasm Transplantation; Nuclear Proteins; Protein Stability; Protein-Arginine N-Methyltransferases; Reverse Genetics; Sorafenib

2021
lncRNA DLGAP1-AS2 Knockdown Inhibits Hepatocellular Carcinoma Cell Migration and Invasion by Regulating miR-154-5p Methylation.
    BioMed research international, 2020, Volume: 2020

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Cell Movement; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Humans; Liver Neoplasms; Male; Methylation; MicroRNAs; Middle Aged; Neoplasm Invasiveness; RNA, Long Noncoding; Survival Analysis; Up-Regulation

2020
Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue.
    Anticancer research, 2020, Volume: 40, Issue:12

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Carcinoma, Hepatocellular; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Male; Methylation; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; RNA; Survival Analysis

2020
5-Aza-2'-deoxycytidine may enhance the frequency of T regulatory cells from CD4
    Expert review of clinical immunology, 2021, Volume: 17, Issue:2

    Topics: Adult; Carcinoma, Hepatocellular; CD4 Antigens; Cell Differentiation; Cells, Cultured; Decitabine; Enzyme Inhibitors; Female; Forkhead Transcription Factors; Gene Expression; Hepatitis B, Chronic; Humans; Immune Tolerance; Liver Cirrhosis; Liver Neoplasms; Male; Methylation; Middle Aged; Programmed Cell Death 1 Receptor; T-Lymphocytes, Regulatory

2021
Fumonisin B
    Archives of toxicology, 2021, Volume: 95, Issue:4

    Topics: Adenosine; Carcinoma, Hepatocellular; Epigenesis, Genetic; Fumonisins; Hep G2 Cells; Humans; Kelch-Like ECH-Associated Protein 1; Liver Neoplasms; Methylation; NF-E2-Related Factor 2; Oxidative Stress; RNA; Signal Transduction

2021
MeCP2 drives hepatocellular carcinoma progression via enforcing HOXD3 promoter methylation and expression through the HB-EGF/EGFR pathway.
    Molecular oncology, 2021, Volume: 15, Issue:11

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Homeodomain Proteins; Humans; Liver Neoplasms; Methyl-CpG-Binding Protein 2; Methylation; Promoter Regions, Genetic; Transcription Factors

2021
PD-L1 and Immune Infiltration of m
    BioMed research international, 2021, Volume: 2021

    Topics: B7-H1 Antigen; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Methylation; MicroRNAs; Prognosis; RNA-Binding Proteins

2021
Histone methylatic modification mediates the tumor-suppressive activity of curcumol in hepatocellular carcinoma via an Hotair/EZH2 regulatory axis.
    Journal of ethnopharmacology, 2021, Nov-15, Volume: 280

    Topics: Carcinoma, Hepatocellular; Cell Survival; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Methylation; Molecular Structure; RNA, Long Noncoding; Sesquiterpenes

2021
SMYD3 promotes hepatocellular carcinoma progression by methylating S1PR1 promoters.
    Cell death & disease, 2021, 07-23, Volume: 12, Issue:8

    Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Sphingosine-1-Phosphate Receptors; Tumor Stem Cell Assay

2021
N6-methyladenosine (m6A) RNA methylation regulator SNRPC is a prognostic biomarker and is correlated with immunotherapy in hepatocellular carcinoma.
    World journal of surgical oncology, 2021, Aug-13, Volume: 19, Issue:1

    Topics: Adenosine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Endothelial Cells; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Liver Neoplasms; Methylation; Prognosis; RNA; Tumor Microenvironment

2021
Reply to A. Braillon.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, 06-20, Volume: 35, Issue:18

    Topics: Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Neoplasm Recurrence, Local; Smoking

2017
Metabolic perturbation of epigenome by inhibiting S-adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Adenosine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Proliferation; Cellular Senescence; Chromatin; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Epigenomics; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53

2017
Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity.
    Cell death & disease, 2017, 05-04, Volume: 8, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dioxygenases; Disease Progression; Histone Demethylases; Histones; Humans; Ikaros Transcription Factor; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Niacinamide; Nuclear Proteins; Phenylurea Compounds; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Signal Transduction; Sorafenib; Transplantation, Heterologous

2017
BORIS up-regulates OCT4 via histone methylation to promote cancer stem cell-like properties in human liver cancer cells.
    Cancer letters, 2017, 09-10, Volume: 403

    Topics: Animals; Antibiotics, Antineoplastic; Binding Sites; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cell Self Renewal; DNA Methylation; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Methylation; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells; Octamer Transcription Factor-3; Phenotype; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; SOXB1 Transcription Factors; Thy-1 Antigens; Time Factors; Transfection; Tumor Burden; Up-Regulation; Xenograft Model Antitumor Assays

2017
Accumulation of histone variant H3.3 with age is associated with profound changes in the histone methylation landscape.
    Nucleic acids research, 2017, Sep-19, Volume: 45, Issue:16

    Topics: Aging; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Hepatocytes; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice, Inbred C57BL; Protein Isoforms; Protein Processing, Post-Translational

2017
Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:3

    Topics: Animals; Arginine; Blotting, Western; Carcinogenesis; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Proliferation; Chromatin Immunoprecipitation; Ethanol; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein-Arginine N-Methyltransferases; Real-Time Polymerase Chain Reaction; Receptors, Cell Surface

2018
Basil polysaccharide attenuates hepatocellular carcinoma metastasis in rat by suppressing H3K9me2 histone methylation under hepatic artery ligation-induced hypoxia.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt B

    Topics: Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Proliferation; Epithelial-Mesenchymal Transition; Hepatic Artery; Histones; Ligation; Liver Neoplasms; Male; Methylation; Neoplasm Metastasis; Neoplasm Proteins; Ocimum basilicum; Polysaccharides; Rats, Wistar; RNA, Messenger

2018
Cell-free DNA: Treasure trove for cancer medicine.
    Nature materials, 2017, 10-25, Volume: 16, Issue:11

    Topics: Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; Circulating Tumor DNA; Humans; Liver Neoplasms; Methylation; Prognosis

2017
Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:1

    Topics: Animals; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Disease Models, Animal; DNA-Binding Proteins; Female; Humans; Liver Neoplasms; Methylation; Mice; Mice, Nude; Protein Binding; Proteins; Proto-Oncogene Proteins; RNA-Binding Proteins; Transcription Factors

2018
Long non-coding RNA CCAL promotes hepatocellular carcinoma progression by regulating AP-2α and Wnt/β-catenin pathway.
    International journal of biological macromolecules, 2018, Apr-01, Volume: 109

    Topics: Acetylation; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Invasiveness; RNA, Long Noncoding; Transcription Factor AP-2; Wnt Signaling Pathway

2018
EZH2 promotes hepatocellular carcinoma progression through modulating miR-22/galectin-9 axis.
    Journal of experimental & clinical cancer research : CR, 2018, Jan-09, Volume: 37, Issue:1

    Topics: 3' Untranslated Regions; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Female; Galectins; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Interferon-gamma; Liver Neoplasms; Methylation; Mice; MicroRNAs; Promoter Regions, Genetic; RNA Interference

2018
Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:3

    Topics: Biomarkers; Carcinoma, Hepatocellular; Case-Control Studies; Co-Repressor Proteins; Female; Humans; Liver Neoplasms; Male; Methylation; Nuclear Proteins; Prognosis; Promoter Regions, Genetic; RNA, Messenger

2018
Epigenetic alterations contribute to promoter activity of imprinting gene IGF2.
    Biochimica et biophysica acta. Gene regulatory mechanisms, 2018, Volume: 1861, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Hep G2 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Lysine; Methylation; Myeloid-Lymphoid Leukemia Protein; Promoter Regions, Genetic; Proto-Oncogene Proteins

2018
Circulating cell-free DNA of methylated insulin-like growth factor-binding protein 7 predicts a poor prognosis in hepatitis B virus-associated hepatocellular carcinoma after hepatectomy.
    Free radical research, 2018, Volume: 52, Issue:4

    Topics: Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Hepatectomy; Hepatitis B virus; Humans; Insulin-Like Growth Factor Binding Proteins; Liver Neoplasms; Methylation; Oxidative Stress; Prognosis

2018
Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/β-catenin signaling.
    EBioMedicine, 2018, Volume: 35

    Topics: Animals; beta Catenin; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Liver Neoplasms; Methylation; Mice, Nude; Models, Biological; Prognosis; Receptors, Androgen; Transcription, Genetic; Up-Regulation; Wnt Signaling Pathway

2018
Increased Trimethylation of histone H3K36 associates with biliary differentiation and predicts poor prognosis in resectable hepatocellular carcinoma.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; beta Catenin; Bile Ducts; Carcinoma, Hepatocellular; Epithelial Cells; Female; Genes, p53; Hepatocyte Nuclear Factor 1-beta; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Keratin-19; Liver Neoplasms; Male; Methylation; Middle Aged; Mutation; Prognosis; Retrospective Studies

2018
DeepM6ASeq: prediction and characterization of m6A-containing sequences using deep learning.
    BMC bioinformatics, 2018, Dec-31, Volume: 19, Issue:Suppl 19

    Topics: Adenosine; Alternative Splicing; Animals; Brain; Carcinoma, Hepatocellular; Computational Biology; Deep Learning; Embryonic Stem Cells; Humans; Liver Neoplasms; Methylation; Mice; RNA; Sequence Analysis, RNA; Zebrafish

2018
A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma.
    Aging, 2019, 01-10, Volume: 11, Issue:1

    Topics: Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; RNA, Messenger

2019
Genome-Wide Screening and Functional Analysis Identifies Tumor Suppressor Long Noncoding RNAs Epigenetically Silenced in Hepatocellular Carcinoma.
    Cancer research, 2019, 04-01, Volume: 79, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Silencing; Genes, Tumor Suppressor; Genome, Human; Histones; Humans; Liver Neoplasms; Methylation; RNA-Binding Proteins; RNA, Long Noncoding

2019
ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma.
    Cell death & disease, 2019, 05-28, Volume: 10, Issue:6

    Topics: 14-3-3 Proteins; Animals; Carcinoma, Hepatocellular; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA-Binding Proteins; Elafin; Hep G2 Cells; Histones; Humans; Liver Neoplasms; MAP Kinase Signaling System; Metallothionein; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Nuclear Proteins; TOR Serine-Threonine Kinases; Transcription Factors; Transplantation, Heterologous

2019
Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma.
    Epigenetics, 2013, Volume: 8, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Animals; Apoptosis; Azacitidine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Carcinogenesis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Decitabine; Epigenesis, Genetic; Female; G2 Phase Cell Cycle Checkpoints; Heterografts; Humans; Liver Neoplasms; Male; Methylation; Mice, Nude; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factor 4; Transcription Factors; Wnt Signaling Pathway

2013
HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Embryo, Mammalian; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocyte Growth Factor; Histone-Lysine N-Methyltransferase; Histones; Humans; Liver Neoplasms, Experimental; Male; Matrix Metalloproteinases, Secreted; Methylation; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Invasiveness; Neoplasm Transplantation; Promoter Regions, Genetic; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins c-met; Signal Transduction; Transcriptional Activation

2013
Mass defect-based pseudo-isobaric dimethyl labeling for proteome quantification.
    Analytical chemistry, 2013, Nov-19, Volume: 85, Issue:22

    Topics: Animals; Carcinoma, Hepatocellular; Isotope Labeling; Liver Neoplasms; Methylation; Mice; Neoplasm Proteins; Peptide Fragments; Proteome; Proteomics; Tandem Mass Spectrometry; Tumor Cells, Cultured

2013
Methylation profile analysis of DNA repair genes in hepatocellular carcinoma with MS-MLPA.
    Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2013, Volume: 22, Issue:4

    Topics: Adult; Aged; Carcinoma, Hepatocellular; DNA; DNA Repair Enzymes; Female; Humans; Male; Methylation; Middle Aged; Nucleic Acid Amplification Techniques; Open Reading Frames; Pathology, Molecular; Promoter Regions, Genetic; Severity of Illness Index

2013
Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Acetylation; beta Catenin; Carcinoma, Hepatocellular; Fluorescent Antibody Technique; Hepatectomy; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Methylation; Multivariate Analysis; Neoplasm Invasiveness; Treatment Outcome; Tumor Suppressor Protein p53

2014
Chain conformation and anti-tumor activity of derivatives of polysaccharide from Rhizoma Panacis Japonici.
    Carbohydrate polymers, 2014, May-25, Volume: 105

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Carcinoma, Hepatocellular; Cell Line, Tumor; Drugs, Chinese Herbal; Glucans; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred BALB C; Panax; Phosphates; Rhizome; Sulfates

2014
Reprogramming using microRNA-302 improves drug sensitivity in hepatocellular carcinoma cells.
    Annals of surgical oncology, 2014, Volume: 21 Suppl 4

    Topics: Apoptosis; Cadherins; Carcinoma, Hepatocellular; Cell Differentiation; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Silencing; Hep G2 Cells; Histone Demethylases; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Kruppel-Like Factor 4; Liver Neoplasms; Methylation; MicroRNAs; Nanog Homeobox Protein; Octamer Transcription Factor-3; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transfection

2014
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Carcinoma, Hepatocellular; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histones; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Staging; Polycomb Repressive Complex 2; Prognosis; Protein Processing, Post-Translational; Proto-Oncogene Proteins

2014
EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:10

    Topics: Animals; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mice, Nude; Polycomb Repressive Complex 2; Repressor Proteins; Signal Transduction; Transcription, Genetic; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2014
Identification of miRNAs that specifically target tumor suppressive KLF6-FL rather than oncogenic KLF6-SV1 isoform.
    RNA biology, 2014, Volume: 11, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hep G2 Cells; Humans; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors; Liver Neoplasms; Methylation; MicroRNAs; Protein Isoforms; Proto-Oncogene Proteins

2014
Histone-modifying genes as biomarkers in hepatocellular carcinoma.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:5

    Topics: Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hepacivirus; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Methylation; Neoplasm Grading; Neoplasm Staging; Phosphorylation; Polycomb Repressive Complex 2; Predictive Value of Tests; Protein Processing, Post-Translational; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Taiwan; Time Factors; Tissue Array Analysis; Up-Regulation

2014
A natural antisense transcript regulates acetylcholinesterase gene expression via epigenetic modification in Hepatocellular Carcinoma.
    The international journal of biochemistry & cell biology, 2014, Volume: 55

    Topics: Acetylcholinesterase; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cisplatin; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mitomycin; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Antisense

2014
Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers.
    The EMBO journal, 2015, Feb-12, Volume: 34, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Histone-Lysine N-Methyltransferase; Histones; Liver Neoplasms; Male; Methylation; Mice; Neoplastic Stem Cells; Tumor Cells, Cultured

2015
Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells.
    Cancer research, 2015, Apr-01, Volume: 75, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Gene Expression; Glucose Transporter Type 1; Glycolysis; Hep G2 Cells; Histone Demethylases; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Methylation; Mice, SCID; Mitochondria, Liver; Neoplasm Transplantation; Protein Processing, Post-Translational; Tumor Burden

2015
Loss of EGF-dependent cell proliferation ability on radioresistant cell HepG2-8960-R.
    Cell biochemistry and function, 2015, Volume: 33, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Cetuximab; Epidermal Growth Factor; Hep G2 Cells; Humans; Liver Neoplasms; Methylation; Promoter Regions, Genetic; Radiation Tolerance

2015
Preoperative serum methylation signature as prognostic tool after curative hepatectomy in patients with hepatocellular carcinoma.
    Anticancer research, 2015, Volume: 35, Issue:2

    Topics: Carcinoma, Hepatocellular; Hepatectomy; Humans; Liver Neoplasms; Methylation; Prognosis

2015
CCNJ detected by triple combination array analysis as a tumor-related gene of hepatocellular carcinoma.
    International journal of oncology, 2015, Volume: 46, Issue:5

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Cyclins; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Tissue Array Analysis; Tumor Cells, Cultured; Young Adult

2015
Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate.
    Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:2

    Topics: Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cohort Studies; Disease-Free Survival; DNA Methylation; Female; Hepatectomy; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Methylation; Middle Aged; Prognosis; Retrospective Studies; Risk Assessment; Statistics, Nonparametric; Survival Analysis

2015
Treg-specific demethylated region activity in isolated regulatory t lymphocytes is a surrogate for disease severity in hepatocellular carcinoma.
    IUBMB life, 2015, Volume: 67, Issue:5

    Topics: Carcinoma, Hepatocellular; Case-Control Studies; Gene Expression; Humans; Liver Neoplasms; Methylation; Severity of Illness Index; T-Lymphocytes, Regulatory

2015
Permethylated Anigopreissin A inhibits human hepatoma cell proliferation by mitochondria-induced apoptosis.
    Chemico-biological interactions, 2015, Jul-25, Volume: 237

    Topics: Apoptosis; Benzofurans; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Hep G2 Cells; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Methylation; Real-Time Polymerase Chain Reaction; Stilbenes

2015
Methylation of tissue factor pathway inhibitor 2 as a prognostic biomarker for hepatocellular carcinoma after hepatectomy.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Hepatocellular; Disease-Free Survival; Female; Glycoproteins; Hepatectomy; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Predictive Value of Tests; Prognosis; Risk; Survival Rate; Young Adult

2016
Hepatitis B virus X protein induces the histone H3 lysine 9 trimethylation on the promoter of p16 gene in hepatocarcinogenesis.
    Experimental and molecular pathology, 2015, Volume: 99, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Genes, p16; Hepatitis B virus; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2015
Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Chi-Square Distribution; DNA Helicases; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Nerve Tissue Proteins; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction

2015
[Hepatitis B virus X protein and methylation of the E-cadherin promoter in hepatocellular carcinoma].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2015, Volume: 23, Issue:7

    Topics: Cadherins; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2015
Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.
    The Journal of pathology, 2016, Volume: 238, Issue:5

    Topics: Animals; Apoptosis; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Liver Neoplasms; Lysine; Methylation; Mice, Nude; Mice, Transgenic; MicroRNAs; NF-kappa B; Polycomb Repressive Complex 2; Promoter Regions, Genetic; RNA Interference; Signal Transduction; Time Factors; Trans-Activators; Transfection; Tumor Burden; Up-Regulation; Viral Regulatory and Accessory Proteins; YY1 Transcription Factor

2016
[Effect of Basil Polysaccharide on Histone H3K9me2 Methylation and Expression of G9a and JMJD1A in Hepatoma Cells Under Hypoxic Conditions].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Liver Neoplasms; Methylation; Ocimum basilicum; Polysaccharides; RNA, Messenger

2015
CLDN14 is epigenetically silenced by EZH2-mediated H3K27ME3 and is a novel prognostic biomarker in hepatocellular carcinoma.
    Carcinogenesis, 2016, Volume: 37, Issue:6

    Topics: beta Catenin; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Claudins; Disease-Free Survival; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Methylation; Prognosis; Wnt Proteins

2016
lnc-β-Catm elicits EZH2-dependent β-catenin stabilization and sustains liver CSC self-renewal.
    Nature structural & molecular biology, 2016, Volume: 23, Issue:7

    Topics: Animals; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hepatocytes; Humans; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplastic Stem Cells; Prognosis; Protein Processing, Post-Translational; Protein Stability; RNA, Long Noncoding; RNA, Small Interfering; Survival Analysis; Transcriptome; Ubiquitination; Wnt Signaling Pathway

2016
Hepatitis B virus X protein influences enrichment profiles of H3K9me3 on promoter regions in human hepatoma cell lines.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Carcinogenesis; Carcinoma, Hepatocellular; Epigenetic Repression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Histones; Humans; Liver Neoplasms; Methylation; Promoter Regions, Genetic; Trans-Activators; Viral Regulatory and Accessory Proteins

2016
Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells.
    Scientific reports, 2017, 01-11, Volume: 7

    Topics: Arginine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Hep G2 Cells; Humans; Liver Neoplasms; Methylation; Models, Biological; Myosin-Light-Chain Phosphatase; Oligonucleotide Array Sequence Analysis; Phosphorylation; Phosphothreonine; Protein Binding; Protein Interaction Mapping; Protein-Arginine N-Methyltransferases; rho-Associated Kinases; Substrate Specificity

2017
ChARM: Discovery of combinatorial chromatin modification patterns in hepatitis B virus X-transformed mouse liver cancer using association rule mining.
    BMC bioinformatics, 2016, Dec-13, Volume: 17, Issue:Suppl 16

    Topics: Algorithms; Animals; Carcinoma, Hepatocellular; Chromatin Immunoprecipitation; CpG Islands; Data Mining; DNA Methylation; Epigenomics; Hepatitis B; Histone Code; Histones; Liver Neoplasms; Methylation; Mice; Promoter Regions, Genetic; Signal Transduction

2016
Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation.
    Nature communications, 2017, 02-27, Volume: 8

    Topics: Acetylation; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Down-Regulation; E1A-Associated p300 Protein; Enzyme Stability; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glucose; Hep G2 Cells; Humans; Liver Neoplasms; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Nuclear Receptor Subfamily 4, Group A, Member 1; Phosphoenolpyruvate Carboxykinase (ATP); Proteolysis; Snail Family Transcription Factors; Sumoylation; Tumor Suppressor Proteins; Ubiquitin-Conjugating Enzymes

2017
A Novel Polysaccharide Conjugate from Bullacta exarata Induces G1-Phase Arrest and Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.
    Molecules (Basel, Switzerland), 2017, Mar-01, Volume: 22, Issue:3

    Topics: Amino Acids; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Carcinoma, Hepatocellular; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Gastropoda; Hep G2 Cells; Humans; Liver Neoplasms; Methylation; Microscopy, Atomic Force; Oncogene Protein p21(ras); Polysaccharides; Proto-Oncogene Proteins c-bcl-2; Spectrum Analysis; Tumor Suppressor Protein p53

2017
Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics.
    The Journal of biological chemistry, 2017, 05-12, Volume: 292, Issue:19

    Topics: Amino Acid Motifs; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Forkhead Box Protein M1; Gene Expression Regulation; Histones; Liver; Liver Neoplasms; Liver Regeneration; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Proteome; RNA, Messenger; Transcriptome

2017
Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
    Journal of gastroenterology, 2008, Volume: 43, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; beta Catenin; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA, Neoplasm; Eye Proteins; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Proteins; Methylation; Microscopy, Fluorescence; Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; TCF Transcription Factors; Transcriptional Activation

2008
Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter.
    Gastroenterology, 2008, Volume: 135, Issue:6

    Topics: Adult; Aged; Cadherins; Carcinoma, Hepatocellular; Chromatin Immunoprecipitation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic; Reactive Oxygen Species; Sequence Analysis, DNA; Tumor Cells, Cultured

2008
Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.
    Cell cycle (Georgetown, Tex.), 2008, Volume: 7, Issue:20

    Topics: Animals; Carcinoma, Hepatocellular; Diet; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Male; Methionine; Methylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Random Allocation; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Transforming Growth Factor beta

2008
Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer.
    Journal of hepatology, 2009, Volume: 50, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Activation; Female; Gene Expression Profiling; Gene Expression Regulation; Histones; Humans; Liver; Liver Neoplasms; Male; Methylation; Middle Aged; Mitogen-Activated Protein Kinase 8; Polycomb Repressive Complex 2; Signal Transduction; Transcription Factors

2009
Control of alternative splicing through siRNA-mediated transcriptional gene silencing.
    Nature structural & molecular biology, 2009, Volume: 16, Issue:7

    Topics: Alternative Splicing; Animals; Argonaute Proteins; Base Sequence; Carcinoma, Hepatocellular; Chromobox Protein Homolog 5; Epigenesis, Genetic; Eukaryotic Initiation Factors; Exons; Fibronectins; Gene Knockdown Techniques; HeLa Cells; Heterochromatin; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice; Oligonucleotides, Antisense; Promoter Regions, Genetic; Ribonuclease III; RNA Interference; RNA Polymerase II; RNA, Small Interfering; Transcription, Genetic

2009
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
    Human pathology, 2010, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Chi-Square Distribution; Cholangiocarcinoma; DNA-Binding Proteins; Female; Gastrointestinal Neoplasms; Histone Demethylases; Histones; Humans; Immunohistochemistry; Liver Neoplasms; Lysine; Male; Methylation; Middle Aged; Nuclear Proteins; Pancreatic Neoplasms; Transcription Factors

2010
Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Apr-02, Volume: 411, Issue:7-8

    Topics: Carcinoma, Hepatocellular; Cyclin D2; Female; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Predictive Value of Tests; Prognosis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2010
Methylation of Dickkopf-3 as a prognostic factor in cirrhosis-related hepatocellular carcinoma.
    World journal of gastroenterology, 2010, Feb-14, Volume: 16, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Biomarkers, Tumor; Biopsy; Carcinoma, Hepatocellular; Chemokines; Female; Humans; Intercellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methylation; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Risk Assessment; ROC Curve

2010
Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter.
    FEBS letters, 2010, Jun-03, Volume: 584, Issue:11

    Topics: Animals; Carcinoma, Hepatocellular; Catalase; CpG Islands; DNA Methylation; Down-Regulation; Liver Neoplasms; Methylation; Reactive Oxygen Species; Regulatory Sequences, Nucleic Acid; RNA, Messenger

2010
Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    The Journal of nutrition, 2011, Volume: 141, Issue:5

    Topics: Carcinoma, Hepatocellular; Cysteine; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Expression; Glycine N-Methyltransferase; Hep G2 Cells; Hepatocytes; Homeostasis; Homocysteine; Humans; Kinetics; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Osmolar Concentration; S-Adenosylhomocysteine; S-Adenosylmethionine

2011
Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.
    Experimental and molecular pathology, 2012, Volume: 92, Issue:3

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Hepatitis, Alcoholic; Hepatocytes; Histones; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Lysine; Mallory Bodies; Methylation; Mice; Microscopy, Electron; Polycomb Repressive Complex 2; Proliferating Cell Nuclear Antigen; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Transcription Factors

2012
A novel quantitative proteomics workflow by isobaric terminal labeling.
    Journal of proteomics, 2012, Oct-22, Volume: 75, Issue:18

    Topics: Animals; Carcinoma, Hepatocellular; Deuterium; Humans; Isotope Labeling; Liver; Liver Neoplasms; Male; Methylation; Oxygen; Oxygen Isotopes; Peptide Fragments; Proteomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Workflow

2012
Pharmacokinetic optimization of class-selective histone deacetylase inhibitors and identification of associated candidate predictive biomarkers of hepatocellular carcinoma tumor response.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Anilides; Animals; Biomarkers, Pharmacological; Carcinoma, Hepatocellular; Cell Line, Tumor; CpG Islands; Drug Screening Assays, Antitumor; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Liver Neoplasms; Methylation; Mice; Microsomes, Liver; Models, Molecular; Molecular Conformation; Morpholines; Neoplasm Transplantation; Pilot Projects; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Transcriptome; Transplantation, Heterologous

2012
Epidermal growth factor receptor signaling in hepatocellular carcinoma: inflammatory activation and a new intracellular regulatory mechanism.
    Digestive diseases (Basel, Switzerland), 2012, Volume: 30, Issue:5

    Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Transformation, Neoplastic; EGF Family of Proteins; ErbB Receptors; Gene Expression Regulation; Glycoproteins; Hepatocytes; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Liver; Liver Neoplasms; MAP Kinase Signaling System; Methylation; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Necrosis Factor-alpha

2012
Detection of TFPI2 methylation in the serum of hepatocellular carcinoma patients.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:4

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Female; Glycoproteins; Humans; Liver; Liver Neoplasms; Male; Methylation; Methyltransferases; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic; Sensitivity and Specificity

2013
Quantitative research of histone H3 acetylation levels of human hepatocellular carcinoma cells.
    Bioanalysis, 2013, Volume: 5, Issue:3

    Topics: Acetylation; Amino Acid Sequence; Carcinoma, Hepatocellular; Chromatography, Liquid; Deuterium; Hep G2 Cells; Histones; Humans; Isotope Labeling; Liver Neoplasms; Methylation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
Suppression of metallothionein-I/II expression and its probable molecular mechanisms.
    Environmental health perspectives, 2002, Volume: 110 Suppl 5

    Topics: Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cytosine; DNA-Binding Proteins; Down-Regulation; Humans; Lymphoma, Non-Hodgkin; Male; Metallothionein; Methylation; Mice; NFI Transcription Factors; Nuclear Proteins; Promoter Regions, Genetic; Prostatic Neoplasms; Rats; Transcription Factors; Tumor Cells, Cultured; Y-Box-Binding Protein 1

2002
Nutritional modulation of gene expression and homocysteine utilization by vitamin B12.
    The Journal of biological chemistry, 2003, Jun-06, Volume: 278, Issue:23

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5' Untranslated Regions; Animals; Carcinoma, Hepatocellular; COS Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Kidney; Liver Neoplasms; Methylation; Nucleic Acid Conformation; Nutritional Physiological Phenomena; Polyribosomes; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured; Vitamin B 12

2003
Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.
    Cancer research, 2003, Apr-15, Volume: 63, Issue:8

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Differentiation; Coculture Techniques; Glutathione Peroxidase; Hematopoietic Stem Cells; Humans; Hydrogen Peroxide; K562 Cells; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lymphoma; Methylation; Neoplasm Proteins; Oncogene Proteins, Fusion; Oxides; Tumor Cells, Cultured

2003
Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines.
    Biochemical and biophysical research communications, 2003, Sep-05, Volume: 308, Issue:4

    Topics: Animals; Carbohydrate Epimerases; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; DNA; DNA Methylation; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Luciferases; Methylation; N-Acetylneuraminic Acid; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2003
Loss of parental-specific methylation at the IGF2 locus in human hepatocellular carcinoma.
    The Journal of pathology, 2003, Volume: 201, Issue:3

    Topics: Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Chromosomes, Human, Pair 11; DNA, Neoplasm; Gene Expression; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Membrane Proteins; Methylation; Polymerase Chain Reaction; Potassium Channels, Voltage-Gated

2003
Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.
    Gastroenterology, 2004, Volume: 126, Issue:1

    Topics: Adult; Aged; Animals; Antiviral Agents; Arginine; Carcinoma, Hepatocellular; Cells, Cultured; DNA-Binding Proteins; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Isoenzymes; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Transgenic; Middle Aged; Phosphoprotein Phosphatases; Protein Inhibitors of Activated STAT; Protein Phosphatase 2; Protein-Tyrosine Kinases; Proteins; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Up-Regulation

2004
Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.
    Journal of gastroenterology, 2004, Volume: 39, Issue:6

    Topics: Carcinoma, Hepatocellular; Carrier Proteins; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Male; Methylation; Middle Aged; Polymerase Chain Reaction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Tumor Cells, Cultured

2004
Suppressor of cytokine signaling 1, a newly proposed tumor suppressor gene associated with hepatocellular carcinoma.
    Journal of gastroenterology, 2004, Volume: 39, Issue:6

    Topics: Carcinoma, Hepatocellular; Carrier Proteins; DNA-Binding Proteins; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Methylation; Repressor Proteins; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2004
S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:4

    Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 8; Caspases; Cell Line, Tumor; Hepatocytes; Homocysteine; Humans; Liver Diseases, Alcoholic; Methylation; Mice; Mice, Inbred C57BL; NF-kappa B; S-Adenosylhomocysteine; Tumor Necrosis Factor-alpha

2004
Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines.
    Biochemical pharmacology, 2005, Apr-01, Volume: 69, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Hepatocytes; Humans; Liver Neoplasms; Methylation; Monocytes; Simvastatin; Stearic Acids

2005
Methylation-based molecular margin analysis in hepatocellular carcinoma.
    Biochemical and biophysical research communications, 2005, Dec-23, Volume: 338, Issue:3

    Topics: Adult; Aged; Base Sequence; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; Female; Humans; Male; Methylation; Middle Aged

2005
Effects of methylated derivatives of Luteolin isolated from Cyperus alopecuroides in rat H4IIE hepatoma cells*.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cyperus; Flowers; Free Radical Scavengers; Luteolin; Methylation; Rats

2006
[A study on the methylation and glutathione S-transferases P1 activity in hepatocellular carcinoma tissues].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2006, Volume: 14, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Female; Glutathione S-Transferase pi; Humans; Liver Neoplasms; Male; Methylation; Methyltransferases; Middle Aged

2006
Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.
    The Journal of pathology, 2007, Volume: 212, Issue:2

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Hepatocellular; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cytoskeletal Proteins; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Liver Neoplasms; Methylation; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic

2007
Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations.
    Cellular and molecular biology (Noisy-le-Grand, France), 2007, Jan-21, Volume: 52 Suppl

    Topics: Adenine Nucleotides; Adenosine; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Chelating Agents; Culture Media; Edetic Acid; Humans; Inosine; Kinetics; Liver Neoplasms; Methylation; S-Adenosylmethionine; Time Factors; Trypsin

2007
Toxic effects of methylated benz[a]anthracenes in liver cells.
    Chemical research in toxicology, 2008, Volume: 21, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; Dose-Response Relationship, Drug; Enzyme Induction; Gap Junctions; Gene Expression Regulation, Enzymologic; Genes, Reporter; Hepatocytes; Liver Neoplasms; Methylation; Rats; Rats, Inbred F344; RNA, Messenger; Stem Cells

2008
DNA methylation and methylase levels in normal and malignant mouse hepatic tissues.
    Carcinogenesis, 1981, Volume: 2, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA (Cytosine-5-)-Methyltransferases; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Rodent Diseases

1981
Clonality in hepatocellular carcinoma: analysis of methylation pattern of polymorphic X-chromosome-linked phosphoglycerate kinase gene in females.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:1

    Topics: Base Sequence; Blotting, Southern; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Genes; Humans; Liver Neoplasms; Methylation; Molecular Sequence Data; Oligonucleotide Probes; Phosphoglycerate Kinase; Polymorphism, Genetic; Ultrasonography; X Chromosome

1995
Developmental- and tissue-specific DNA methylation patterns and expression of rat gamma-glutamyltransferase.
    Biochemistry and molecular biology international, 1995, Volume: 36, Issue:2

    Topics: Animals; Blotting, Southern; Carcinoma, Hepatocellular; DNA; Electrophoresis, Agar Gel; Fetal Heart; gamma-Glutamyltransferase; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Kidney; Liver; Lung; Male; Methylation; Myocardium; Organ Specificity; Pancreas; Rats; Rats, Sprague-Dawley

1995
Expression and hypomethylation of alpha-fetoprotein gene in unicentric and multicentric human hepatocellular carcinomas.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; DNA; Gene Expression; Humans; Liver Neoplasms; Methylation; Middle Aged; RNA, Messenger; Transcription, Genetic

1993
Basal promoter of the rat connexin 32 gene: identification and characterization of an essential element and its DNA-binding protein.
    Molecular and cellular biology, 1995, Volume: 15, Issue:3

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Connexins; DNA; DNA Mutational Analysis; DNA Primers; Exons; Gap Junction beta-1 Protein; Gene Expression; Humans; Liver; Liver Neoplasms; Male; Methylation; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Organ Specificity; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1995
Clonal analysis of regenerative nodules in hepatitis C virus-induced liver cirrhosis.
    Gastroenterology, 1994, Volume: 107, Issue:6

    Topics: Base Sequence; Carcinoma, Hepatocellular; Gene Expression Regulation, Enzymologic; Genetic Linkage; Hepatitis C; Humans; Hyperplasia; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Regeneration; Methylation; Molecular Sequence Data; Phosphoglycerate Kinase; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; X Chromosome

1994
DNA hypomethylation of proliferating cell nuclear antigen gene in human hepatocellular carcinoma is not due to cell proliferation.
    Cancer letters, 1993, Jul-16, Volume: 70, Issue:3

    Topics: Animals; Antigens, Neoplasm; Blotting, Northern; Blotting, Southern; Carcinoma, Hepatocellular; Cell Division; DNA Probes; DNA, Neoplasm; Humans; Liver; Liver Neoplasms; Male; Methylation; Nuclear Proteins; Polymorphism, Restriction Fragment Length; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; RNA, Messenger; Tumor Cells, Cultured

1993
3-Deazaadenosine and MDL29350 differentially affect the methylation of serine-and ethanolamine-derived phosphatidylethanolamine in Hep G2 cells.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:12

    Topics: Caproates; Carcinoma, Hepatocellular; Cell Line; Ethanolamine; Ethanolamines; Humans; Hypolipidemic Agents; Isomerism; Liver Neoplasms; Methylation; Phosphatidylethanolamines; Serine; Tritium; Tubercidin; Tumor Cells, Cultured

1993
Aberrations of p53 gene in human hepatocellular carcinoma from China.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Aflatoxin B1; Base Sequence; Blotting, Southern; Carcinoma, Hepatocellular; China; Chromosome Aberrations; DNA, Neoplasm; DNA, Single-Stranded; Environmental Exposure; Genes, p53; Hepatitis B; Humans; Liver Neoplasms; Methylation; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Risk Factors

1993
Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures.
    Steroids, 1995, Volume: 60, Issue:9

    Topics: Carcinoma, Hepatocellular; Chromans; Equol; Estradiol; Estrogens, Non-Steroidal; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Methylation; RNA, Messenger; Sex Hormone-Binding Globulin; Transcription, Genetic; Tumor Cells, Cultured

1995
Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver.
    Mutation research, 1996, Jul-05, Volume: 354, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carcinoma, Hepatocellular; Child; Child, Preschool; DNA; Female; Genes, fos; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Methylation; Middle Aged

1996
Regulation of human C-reactive protein gene expression by two synergistic IL-6 responsive elements.
    Biochemistry, 1996, Jul-16, Volume: 35, Issue:28

    Topics: Base Sequence; Binding Sites; C-Reactive Protein; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Chloramphenicol O-Acetyltransferase; DNA Probes; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Hepatocyte Nuclear Factor 3-alpha; Humans; Interleukin-6; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Regulatory Sequences, Nucleic Acid; Transcription Factors; Transfection; Tumor Cells, Cultured

1996
Distinct positive and negative regulatory elements control neuronal and hepatic transcription of the human transferrin gene.
    Journal of neuroscience research, 1996, Feb-01, Volume: 43, Issue:3

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line; Chloramphenicol O-Acetyltransferase; Choroid Plexus; Deoxyribonuclease I; DNA Footprinting; Gene Expression Regulation, Neoplastic; Humans; Liver; Methylation; Molecular Sequence Data; Neuroblastoma; Neurons; Nuclear Proteins; Oligodendroglia; Oligodeoxyribonucleotides; Organ Specificity; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Transfection; Transferrin; Tumor Cells, Cultured

1996
p16(INK4) is inactivated by extensive CpG methylation in human hepatocellular carcinoma.
    Gastroenterology, 1999, Volume: 116, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Immunohistochemistry; Liver Neoplasms; Male; Methylation; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational

1999
p16(INK4): involvement early and often in gastrointestinal malignancies.
    Gastroenterology, 1999, Volume: 116, Issue:2

    Topics: Carcinoma, Hepatocellular; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation

1999
DNA hypermethylation at the D17S5 locus and reduced HIC-1 mRNA expression are associated with hepatocarcinogenesis.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:3

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Chromosome Mapping; DNA; Female; Humans; Kruppel-Like Transcription Factors; Liver; Liver Neoplasms; Loss of Heterozygosity; Male; Methylation; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors

1999
p16 is a major inactivation target in hepatocellular carcinoma.
    Cancer, 2000, Jul-01, Volume: 89, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Gene Deletion; Genes, p16; Humans; Liver Neoplasms; Methylation; Promoter Regions, Genetic; Proteins; RNA; Transcription Factors; Tumor Suppressor Protein p14ARF; Tumor Suppressor Proteins

2000
Relationship of p16 methylation status and serum alpha-fetoprotein concentration in hepatocellular carcinoma patients.
    Clinical chemistry, 2000, Volume: 46, Issue:9

    Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; Humans; Immunoassay; Liver Neoplasms; Methylation; Polymerase Chain Reaction; Tumor Cells, Cultured

2000
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: Carcinoma, Hepatocellular; Enzymes; Humans; Isoenzymes; Liver; Liver Cirrhosis; Liver Neoplasms; Methionine; Methionine Adenosyltransferase; Methylation; Promoter Regions, Genetic; RNA, Messenger

2000
Clonal analysis of hepatocellular carcinoma and dysplastic nodule by methylation pattern of X-chromosome-linked human androgen receptor gene.
    Cancer letters, 2001, Mar-10, Volume: 164, Issue:1

    Topics: Adult; Aged; Carcinoma, Hepatocellular; DNA Methylation; Humans; Liver; Liver Neoplasms; Luminescent Measurements; Methylation; Middle Aged; Polymerase Chain Reaction; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; X Chromosome

2001
Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells.
    The Journal of biological chemistry, 2002, Jun-21, Volume: 277, Issue:25

    Topics: Alleles; Blotting, Northern; Carcinoma, Hepatocellular; Chromatin; CpG Islands; DNA Methylation; DNA-Binding Proteins; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Immunoblotting; Isoenzymes; Luciferases; Methylation; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2002
Reciprocal relationship between methylation status and loss of heterozygosity at the p14(ARF) locus in Australian and South African hepatocellular carcinomas.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:3

    Topics: Adult; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 9; Cyclin-Dependent Kinase Inhibitor p16; Female; Genes, Tumor Suppressor; Helminth Proteins; Humans; Liver Neoplasms; Loss of Heterozygosity; Male; Methylation; Middle Aged; Muscle Proteins; Mutation; Polymerase Chain Reaction; Tumor Suppressor Protein p53

2002
Interrelationships between synthesis and methylation of ribosomal RNA in isolated Novikoff Tumor nucleoli.
    Biochemistry, 1975, Jan-14, Volume: 14, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cations, Divalent; Cell Nucleolus; DNA-Directed RNA Polymerases; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer; Transcription, Genetic; tRNA Methyltransferases

1975
Sulfhydryl group quantitation of hepatoma and liver microsomal fractions.
    Cancer research, 1975, Volume: 35, Issue:6

    Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Disulfides; Edetic Acid; Endoplasmic Reticulum; Female; Iodamide; Liver; Liver Neoplasms; Male; Methylation; Microsomes, Liver; Neoplasms, Experimental; Polyribosomes; Potassium Chloride; Protein Binding; Protein Conformation; Pyridines; Rats; Sex Factors; Sulfhydryl Compounds; Sulfhydryl Reagents; Urea

1975
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
    Nucleic acids research, 1975, Volume: 2, Issue:6

    Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine

1975
Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus.
    Biochemistry, 1975, Oct-07, Volume: 14, Issue:20

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Liver Neoplasms; Methylation; Neoplasms, Experimental; Poly A; Rats; RNA, Messenger; RNA, Neoplasm; Waxes

1975
Interaction of normal and tumor transfer RNA methyltransferases with ethionine-induced methyl-deficient rat liver transfer RNA.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Carcinoma, Hepatocellular; Escherichia coli; Ethionine; Female; Kinetics; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Transfer; tRNA Methyltransferases

1975
The topographical order of 18 S and 20 S ribosomal ribonucleic acids within the 45 S precursor molecule.
    Journal of molecular biology, 1975, Oct-25, Volume: 98, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; Ribosomes; RNA, Neoplasm; RNA, Ribosomal

1975
Tissue specific differences in the 2'-O-methylation of eukaryotic 5.8S ribosomal RNA.
    FEBS letters, 1975, Nov-01, Volume: 59, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Guanine Nucleotides; Humans; Liver; Liver Neoplasms; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Ribosomal; Structure-Activity Relationship; Uracil Nucleotides; Uridine Monophosphate

1975
Kinetics of Novikoff cytoplasmic messenger RNA methylation.
    Biochemistry, 1976, Nov-30, Volume: 15, Issue:24

    Topics: Carcinoma, Hepatocellular; Cell Line; Cytoplasm; Kinetics; Liver Neoplasms; Methylation; Neoplasms, Experimental; Oligoribonucleotides; Ribonucleosides; Ribonucleotides; RNA, Messenger

1976
Inhibition of RNA methylation by intercalating agents.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Alkaloids; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Ellipticines; Ethidium; Hycanthone; In Vitro Techniques; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer; Thioxanthenes; tRNA Methyltransferases

1977
Tumour-specific phenylalanine tRNA contains two supernumerary methylated bases.
    Nature, 1978, Jan-12, Volume: 271, Issue:5641

    Topics: Animals; Base Sequence; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Liver Neoplasms; Methylation; Mice; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; tRNA Methyltransferases

1978
Identification of cis- and trans-acting factors regulating the expression of the human insulin receptor gene.
    The Journal of biological chemistry, 1992, Mar-05, Volume: 267, Issue:7

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cells, Cultured; Chloramphenicol O-Acetyltransferase; DNA Fingerprinting; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation; Humans; Liver Neoplasms; Methylation; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Rats; Receptor, Insulin; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1992
The aetiology of cancer in the very young.
    The British journal of cancer. Supplement, 1992, Volume: 18

    Topics: Base Sequence; Carcinoma, Hepatocellular; Case-Control Studies; Child, Preschool; DNA; DNA Replication; Eye Neoplasms; Humans; Incidence; Infant; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Methylation; Models, Genetic; Registries; Retinoblastoma; United States; Wilms Tumor

1992
The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Diet; Diethylnitrosamine; DNA Probes; DNA, Neoplasm; Liver Neoplasms, Experimental; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344

1992
Abnormalities of insulin-like growth factor (IGF-I and IGF-II) genes in human tumor tissue.
    Growth regulation, 1992, Volume: 2, Issue:1

    Topics: Alleles; Blotting, Northern; Blotting, Southern; Carcinoma, Hepatocellular; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Fibroma; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Leiomyoma; Leukocytes; Liver Neoplasms; Lymphoma, Non-Hodgkin; Methylation; Neuroblastoma; Polymorphism, Restriction Fragment Length; RNA, Messenger; Tumor Cells, Cultured

1992
Bile acid synthesis in cultured human hepatoblastoma cells.
    The Journal of biological chemistry, 1991, Sep-25, Volume: 266, Issue:27

    Topics: Bile Acids and Salts; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Cholic Acids; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Liver Neoplasms; Mass Spectrometry; Methylation; Steroids; Tumor Cells, Cultured

1991
Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors.
    Journal of toxicology and environmental health, 1991, Volume: 34, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Chloroform; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylation; Mice; Phenobarbital; Restriction Mapping; Rodent Diseases

1991
Cell-type specific and differential regulation of the human metallothionein genes. Correlation with DNA methylation and chromatin structure.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Azacitidine; Carcinoma, Hepatocellular; Cell Line; Chloramphenicol O-Acetyltransferase; Chromatin; DNA; Gene Expression Regulation; Genes; Humans; Kinetics; Liver Neoplasms; Metallothionein; Methylation; Organ Specificity; Plasmids; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1990
Point mutation, allelic loss and increased methylation of c-Ha-ras gene in human hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:1

    Topics: Adult; Alleles; Carcinoma, Hepatocellular; Chromosome Deletion; Codon; DNA, Neoplasm; DNA, Viral; Female; Genes, ras; Hepatitis B virus; Heterozygote; Humans; Liver Neoplasms; Male; Methylation; Middle Aged; Mutation

1991
Interleukin-1-mediated enhancement of mouse factor B gene expression via NF kappa B-like hepatoma nuclear factor.
    Molecular and cellular biology, 1990, Volume: 10, Issue:12

    Topics: Animals; Base Sequence; Binding Sites; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Complement Factor B; Gene Expression; Humans; Interleukin-1; Liver Neoplasms; Methylation; Mice; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; Oligonucleotide Probes; Plasmids

1990
Hypomethylation of the c-myc oncogene in liver cirrhosis and chronic hepatitis.
    Gastroenterologia Japonica, 1989, Volume: 24, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blotting, Southern; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Exons; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Methylation; Middle Aged; Oncogenes

1989
Presence of fucosylated triantennary, tetraantennary and pentaantennary glycans in transferrin synthesized by the human hepatocarcinoma cell line Hep G2.
    European journal of biochemistry, 1989, Sep-15, Volume: 184, Issue:2

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Carcinoma, Hepatocellular; Cell Line; Chromatography, Affinity; Fucose; Humans; Immunoelectrophoresis, Two-Dimensional; Liver Neoplasms; Methylation; Molecular Sequence Data; Molecular Weight; Oligosaccharides; Radioimmunoassay; Transferrin

1989
Comparative study of the sugar chains of gamma-glutamyltranspeptidases purified from human hepatocellular carcinoma and from human liver.
    Journal of biochemistry, 1989, Volume: 105, Issue:5

    Topics: Carbohydrates; Carcinoma, Hepatocellular; Chromatography, Affinity; Electrophoresis, Paper; gamma-Glutamyltransferase; Glycoside Hydrolases; Humans; Liver; Liver Neoplasms; Methylation; Oligosaccharides

1989
Effects of denaturation and methylation on the degradation of proteins in cultured hepatoma cells and in reticulocyte cell-free systems.
    European journal of biochemistry, 1985, Jan-15, Volume: 146, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell-Free System; Cells, Cultured; Chymotrypsin; Cytochrome c Group; Lactoglobulins; Liver Neoplasms; Methylation; Protein Denaturation; Reticulocytes; Serum Albumin; Trypsin

1985
Hypomethylation of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:12

    Topics: Carcinoma, Hepatocellular; ErbB Receptors; Gene Expression Regulation; Genes; Humans; Liver; Liver Neoplasms; Methylation; Oncogene Proteins, Viral; Proto-Oncogenes; Receptors, Cell Surface

1985
Site-specific hypomethylation of the c-myc oncogene in human hepatocellular carcinoma.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:7

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line; Deoxyribonuclease I; DNA, Neoplasm; Exons; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Methylation; Oncogenes; Substrate Specificity

1987
Unmasking of proteins by in vitro methylation of rat liver RNA during azo dye carcinogenesis.
    Stain technology, 1971, Volume: 46, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Coloring Agents; Cytoplasm; Histocytochemistry; Liver; Liver Neoplasms; Methods; Methylation; Microscopy; Neoplasm Proteins; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Proteins; Rats; RNA; RNA, Neoplasm; Staining and Labeling; Temperature

1971
Transfer RNA methylase activity in normal monkey liver and in carcinogen-induced hepatoma.
    Cancer research, 1971, Volume: 31, Issue:8

    Topics: Alpha-Globulins; Animals; Carcinogens; Carcinoma, Hepatocellular; Chromatography; Female; Fetal Proteins; Haplorhini; Liver; Liver Neoplasms; Macaca; Male; Methylation; Neoplasms, Experimental; Nitroso Compounds; Ribonucleases; RNA, Neoplasm; RNA, Transfer

1971
Early appearance of serum -fetoprotein during hepatocarcinogenesis as a function of age of rats and extent of treatment with 3'-methyl-4-dimethylaminoazobenzene.
    Cancer research, 1972, Volume: 32, Issue:7

    Topics: Age Factors; Alpha-Globulins; Animals; Carcinoma, Hepatocellular; Immunodiffusion; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Thiocyanates

1972
Fractionation of nuclear ribonucleic acids from tumor and homologous tissue on a methylated albumin column by the use of salt and temperature gradients.
    Biochimica et biophysica acta, 1967, Apr-18, Volume: 138, Issue:2

    Topics: Albumins; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA; RNA, Neoplasm; Sodium Chloride; Temperature

1967
Kethyl activation and sRNA methylation by soluble fractions of several vertebrate livers.
    Canadian journal of biochemistry, 1967, Volume: 45, Issue:10

    Topics: Animals; Anura; Carcinoma, Hepatocellular; Chickens; Dogs; Female; Fishes; Glucosyltransferases; Liver; Liver Neoplasms; Male; Methylation; Mice; Molecular Biology; Rabbits; Rats; RNA, Transfer; Sharks; Snakes; Species Specificity; Turtles

1967
Hepatotoxic and carcinogenic effects of dimethylnitrosamine in low dosage. Light and electron microscopic study.
    Journal of the National Cancer Institute, 1968, Volume: 40, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Female; Liver; Liver Neoplasms; Methylation; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Rats

1968
Studies on nucleolar 4 to 6 S ribonucleic acid of Novikoff hepatoma cells.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Gel; Cytosine Nucleotides; Electrophoresis, Disc; Leucine; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Rats; Ribosomes; RNA; Templates, Genetic; Uracil Nucleotides

1968
Soluble RNA ethylase activity of normal and neoplastic mouse tissues.
    Cancer research, 1968, Volume: 28, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Escherichia coli; Liver; Liver Neoplasms; Magnesium; Methylation; Mice; Nucleotides; RNA, Bacterial; RNA, Transfer; Saccharomyces; Time

1968
Biochemical, pathological, and genetic aspects of a spontaneous mouse hepatoma.
    Journal of the National Cancer Institute, 1969, Volume: 43, Issue:2

    Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Diet; Fatty Liver; Female; Hybridization, Genetic; Karyotyping; L-Serine Dehydratase; Liver; Liver Neoplasms; Male; Methylation; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; Sex Factors; Transaminases; Transferases; Vitamin E

1969
Studies on DNA methylase activity in mammalian tissue.
    Experientia, 1969, Apr-15, Volume: 25, Issue:4

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; Edetic Acid; Liver; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Quaternary Ammonium Compounds; Salmonidae; Testis; Transferases

1969
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
    Journal of molecular biology, 1969, Jun-14, Volume: 42, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine

1969
The effects of local x irradiation on the relative rates of incorporation of thymidine-methyl-5-3H and cytidine-5-3H into mitochondrial and nuclear DNA of Morris hepatoma 3924A.
    Radiology, 1969, Volume: 93, Issue:5

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver Neoplasms; Methylation; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Radiography; Radiotherapy Dosage; Rats; Thymidine; Tritium

1969
Studies on the nuclear 4 to 7 s RNA of the Novikoff hepatoma.
    Journal of molecular biology, 1969, Volume: 39, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Gel; Densitometry; Electrophoresis; Formates; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleotides; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides

1969
Methylation of transfer RNA and of ribosomal RNA in rat liver in the intact animal and the effect of carcinogens.
    Biochimica et biophysica acta, 1969, Dec-16, Volume: 195, Issue:2

    Topics: Aflatoxins; Animals; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Paper; Ethionine; Female; Intestine, Small; Kinetics; Liver; Liver Neoplasms; Male; Methionine; Methylation; Models, Biological; Models, Chemical; Nitrosamines; Nucleotides; Perchlorates; Precancerous Conditions; Protein Biosynthesis; Purinones; Rats; Ribosomes; RNA; RNA, Neoplasm; RNA, Transfer; Stimulation, Chemical; Time Factors

1969
Natural inhibitors of the transfer ribonucleic acid methylases.
    Biochemistry, 1970, Feb-03, Volume: 9, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chemical Precipitation; Dialysis; Drug Stability; Escherichia coli; Female; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Omentum; Pregnancy; Quaternary Ammonium Compounds; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; Transferases; Trypsin; Ultracentrifugation

1970
Structural analysis of nucleolar precursors of ribosomal ribonucleic acid. Studies on the 5'-terminal and alkali-resistant dinucleotides of nucleolar high molecular weight ribonucleic acid.
    The Journal of biological chemistry, 1970, Apr-25, Volume: 245, Issue:8

    Topics: Adenine Nucleotides; Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Cytosine Nucleotides; Hydroxides; Liver Neoplasms; Male; Methylation; Nucleotides; Phosphorus Isotopes; Potassium; Rats; Ribosomes; RNA, Neoplasm; Uracil Nucleotides

1970
Ribonucleotide reductase and cell proliferation. I. Variations of ribonucleotide reductase activity with tumor growth rate in a series of rat hepatomas.
    The Journal of biological chemistry, 1970, Oct-25, Volume: 245, Issue:20

    Topics: Alcohol Oxidoreductases; Animals; Bacterial Proteins; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Cell Division; Cell-Free System; DNA; Liver; Liver Neoplasms; Male; Methylation; Oxidoreductases; Rats; Thymidine Kinase; Transferases; Tritium; Uracil Nucleotides

1970
Histone methylase activity of adult, embryonic and neoplastic liver tissues.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1970, Aug-22, Volume: 9, Issue:16

    Topics: Animals; Brain; Carcinoma, Hepatocellular; Cattle; Fetus; Histones; Kidney; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rabbits; RNA; Spleen; Transferases

1970
Methylation of preribosomal and transfer RNA's by isolated nucleoli of the Novikoff rat tumor.
    Biochimica et biophysica acta, 1970, Nov-12, Volume: 224, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Cytosine Nucleotides; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Rats; RNA; RNA, Transfer; Tritium

1970
Change of glycolipid pattern in Morris hepatomas 5123 and 7800.
    Cancer research, 1970, Volume: 30, Issue:12

    Topics: Animals; Animals, Newborn; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Glycolipids; Liver; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; Neuraminic Acids; Rats

1970
Agents of modulation of the transfer RNA methylases.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Castration; Chromatography; Chromatography, Gel; Enzyme Inhibitors; Estradiol; Female; Guanine; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Methylation; Methyltransferases; Molecular Weight; Neoplasms, Experimental; Rabbits; Rats; RNA, Transfer; Swine; Transferases; Uterus

1971
Transfer RNA's of embryonic tissue.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Animals; Carcinoma, Hepatocellular; Cattle; Cell-Free System; Embryo, Mammalian; Female; Gestational Age; Leucine; Ligases; Liver; Liver Neoplasms; Methylation; Mice; Pregnancy; Proteins; Rabbits; RNA, Transfer; Tritium

1971
Methylation of transfer RNA by monkey liver and hepatoma induced by N-nitrosodiethylamine.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:1

    Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Escherichia coli; Fetal Proteins; Haplorhini; Liver; Liver Extracts; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nitrosamines; RNA, Bacterial; RNA, Transfer

1971
Methylation of mammalian deoxyribonucleic acid. II. The distribution of 5-methylcytosine in pyrimidine deoxyribonucleotide clusters in Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1971, Aug-10, Volume: 246, Issue:15

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Techniques; Cytosine; Cytosine Nucleotides; Deamination; Deoxyribonucleotides; DNA, Neoplasm; Formates; Hydrolysis; Liver Neoplasms; Methionine; Methods; Methylation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Polynucleotides; Ribonucleases; Snakes; Spectrophotometry; Thymine Nucleotides; Venoms

1971
Uptake of label into methylated amino acids from rat tissue histones after in vivo administration of (Me- 14 C)methionine.
    Biochimica et biophysica acta, 1971, May-13, Volume: 238, Issue:2

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Histones; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymus Gland; Time Factors

1971
Coding properties of tRNA glu of mammalian origin: comparison between rat liver and minimal deviation hepatoma 5123C tRNA's glu .
    Biochemical and biophysical research communications, 1971, Volume: 45, Issue:4

    Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Escherichia coli; Genetic Code; Glutamates; Liver; Liver Neoplasms; Methylation; Nucleotides; RNA, Neoplasm; RNA, Transfer; Sulfhydryl Compounds; Templates, Genetic; Thiouracil; Tritium; Uridine; Yeasts

1971
Protein methylases in hepatomas.
    Cancer research, 1972, Volume: 32, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Histones; Liver Neoplasms; Methylation; Methyltransferases; Neoplasm Proteins; Neoplasms, Experimental; Rats; S-Adenosylmethionine

1972
Altered regulation of the transport of RNA from nucleus to cytoplasm in rat hepatoma cells.
    Cancer research, 1972, Volume: 32, Issue:2

    Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Fetus; Liver; Liver Neoplasms; Liver Regeneration; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; RNA, Neoplasm

1972
Influence of age and sex on hepatic lesions induced by chemical carcinogens: ingestion of 3'-methyl-4-dimethylaminoazobenzene by Buffalo strain rats.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:3

    Topics: Adenoma, Bile Duct; Age Factors; Animals; Carcinoma, Hepatocellular; Female; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Male; Methylation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Sex Factors

1972
Methylation patterns of transfer RNA from ascites hepatomas.
    Biochimica et biophysica acta, 1972, Jan-18, Volume: 259, Issue:1

    Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Cytosine Nucleotides; Guanine Nucleotides; Inosine Nucleotides; Liver; Liver Neoplasms; Methionine; Methylation; Nucleotides; Rats; RNA, Transfer; Tritium; Uracil Nucleotides

1972
Methylation of mammalian deoxyribonucleic acid. 3. Terminal versus internal location of 5-methylcytosine in oligodeoxyribonucleotides from Novikoff hepatoma cell deoxyribonucleic acid.
    The Journal of biological chemistry, 1972, May-10, Volume: 247, Issue:9

    Topics: Alkaline Phosphatase; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Clone Cells; Cytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Escherichia coli; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats; Spleen; Venoms

1972
-Glutamyl transpeptidase in transplantable, chemically induced rat hepatomas and "spontaneous" mouse hepatomas.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:5

    Topics: Acyltransferases; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Colorimetry; Cysteine; Female; Fetus; Glutathione; Hydro-Lyases; Liver Neoplasms; Male; Methylation; Neoplasm Transplantation; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Polarography; Rats

1972
Specific enhancement of hepatoma growth using methylated bovine serum albumin and pertussis vaccine.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 26, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Membrane; Female; Immunity, Cellular; Liver Neoplasms; Methylation; Neoplasms, Experimental; Pertussis Vaccine; Rats; Rats, Inbred Strains; Serum Albumin, Bovine

1972
Competing methyltransferase systems.
    The Journal of biological chemistry, 1972, Jul-10, Volume: 247, Issue:13

    Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Glycine; Homocysteine; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Mice; Molecular Weight; Pancreas; Rabbits; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine

1972
Vitamin B 12 and methionine metabolism in the Buffalo rat liver and Morris 5123 hepatoma.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Choline Deficiency; Fatty Liver; Folic Acid; Homocystine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Methionine; Methylation; Neoplasms, Experimental; Nutrition Disorders; Rats; Vitamin B 12; Vitamin B 12 Deficiency

1972
Focal loss of ribonuclease activity in preneoplastic rat liver.
    Cancer research, 1972, Volume: 32, Issue:11

    Topics: Animals; Carcinoma, Hepatocellular; Diet; Histocytochemistry; Liver; Liver Diseases; Liver Neoplasms; Male; Methylation; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Ribonucleases

1972
In vivo turnover and distribution of radio-N-methyl in arginine-rich histones from rat tissues.
    Archives of biochemistry and biophysics, 1972, Volume: 152, Issue:2

    Topics: Animals; Arginine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Histones; Kinetics; Liver; Liver Neoplasms; Lysine; Male; Methionine; Methylation; Neoplasms, Experimental; Rats; Spleen

1972
Inhibition of transfer and ribosomal RNA methylases by polyinosinate.
    Cancer research, 1973, Volume: 33, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleolus; Inosine Nucleotides; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Polynucleotides; Rats; RNA, Neoplasm; RNA, Ribosomal; RNA, Transfer

1973
1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.
    Cancer research, 1973, Volume: 33, Issue:3

    Topics: Acetylation; Administration, Oral; Allyl Compounds; Animals; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Dioxoles; Female; Hemangiosarcoma; Hydroxylation; Injections, Subcutaneous; Liver Neoplasms; Lymphoma; Male; Methylation; Mice; Neoplasms, Experimental; Papilloma; Rats; Sarcoma; Skin Neoplasms; Stomach Neoplasms

1973
A study of transfer RNA methylation.
    Biochimica et biophysica acta, 1973, Jan-19, Volume: 294, Issue:2

    Topics: Animals; Base Sequence; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Cytosol; Kinetics; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Polynucleotides; Rats; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Transfer RNA Aminoacylation; Valine

1973
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine

1973
Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma.
    Biochimica et biophysica acta, 1973, Mar-28, Volume: 299, Issue:3

    Topics: Amino Acids; Ammonium Sulfate; Animals; Brain; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Escherichia coli; Female; Kidney; Liver; Liver Neoplasms; Methylation; Methyltransferases; Muscles; Mycoplasma; Neoplasms, Experimental; Rats; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Saccharomyces cerevisiae; Spleen

1973
A study of transfer RNA methylation.
    Biochimica et biophysica acta, 1973, Jan-19, Volume: 294, Issue:1

    Topics: Animals; Base Sequence; Binding Sites; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Rats; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Valine

1973
Transfer RNA base composition studies in Morris hepatomas and rat liver.
    Cancer research, 1974, Volume: 34, Issue:3

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cytidine; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Transfer; Tritium; Uridine

1974
Differences in in vivo methylation patterns of tyrosine and histidine transfer ribonucleic acids from rat liver and Novikoff hepatoma.
    Biochemistry, 1974, Mar-12, Volume: 13, Issue:6

    Topics: Adenine; Amino Acyl-tRNA Synthetases; Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Cytosine; Guanine; Histidine; Hypoxanthines; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Ribonucleotides; RNA, Neoplasm; RNA, Transfer; Tritium; Tyrosine

1974
[Varying rate of destruction of alkylated molecules of RNA, protein and lipids in normal and neoplastic cells].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 76, Issue:11

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; Lipid Metabolism; Liver; Liver Neoplasms; Methylation; Mice; Mice, Inbred C3H; Neoplasm Proteins; Neoplasms, Experimental; Nitrosourea Compounds; RNA, Neoplasm; Spleen

1973
Patterns of excretion of methylated purines in hepatocellular carcinoma.
    Cancer research, 1974, Volume: 34, Issue:5

    Topics: Adenine; Adult; Carcinoma, Hepatocellular; Chromatography, Paper; Creatine; Guanine; Humans; Hydrolysis; Liver Cirrhosis; Liver Neoplasms; Male; Methylation; Purines

1974
The formation of methylated bases in DNA by dimethylnitrosamine and its relation to differences in the formation of tumours in the livers of GR and C3HF mice.
    Chemico-biological interactions, 1974, Volume: 8, Issue:5

    Topics: Animals; Carbon Radioisotopes; Carcinogens; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Chromatography, Thin Layer; DNA; Fasting; Female; Half-Life; Liver; Liver Neoplasms; Male; Methylation; Mice; Mice, Inbred Strains; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Oxidoreductases, N-Demethylating; Species Specificity; Time Factors

1974
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
    Cell differentiation, 1972, Volume: 1, Issue:3

    Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine

1972
Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:10

    Topics: Adenosine; Carcinoma, Hepatocellular; Cell Fractionation; Cell Line; Cellulose; Chromatography; Cytidine; Guanosine; Liver Neoplasms; Methylation; Neoplasms, Experimental; Nucleosides; Oligonucleotides; Polyribosomes; RNA, Messenger; RNA, Neoplasm; Thymine Nucleotides

1974
Base analysis of RNA by 3H postlabeling--a study of ribothymidine content and degree of base methylation of 4 S RNA.
    Biochimica et biophysica acta, 1974, Oct-11, Volume: 366, Issue:2

    Topics: Animals; Bacillus subtilis; Brain Chemistry; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Cytosol; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorescence; Isotope Labeling; Liver; Liver Neoplasms; Methylation; Mitochondria, Liver; Muscles; Neoplasms, Experimental; Organ Specificity; Rats; Ribonucleotides; RNA; RNA, Bacterial; RNA, Transfer; Tritium; Uridine

1974
Effect of ethionine on the synthesis and transfer of active methyl groups.
    Physiological chemistry and physics, 1972, Volume: 4, Issue:6

    Topics: Animals; Bacillus subtilis; Carcinoma, Hepatocellular; Cricetinae; Escherichia coli; Ethionine; Female; Liver; Liver Neoplasms; Male; Methylation; Mice; Quaternary Ammonium Compounds; Rats; RNA, Transfer; S-Adenosylmethionine; tRNA Methyltransferases

1972
Transfer-RNA methylase activity in rat ascites hepatomas: Altered methylation patterns in the presence of guanidine carbonate.
    Gan, 1974, Volume: 65, Issue:6

    Topics: Animals; Bicarbonates; Carbon Radioisotopes; Carbonates; Carcinoma, Hepatocellular; Escherichia coli; Guanidines; Guanine; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; tRNA Methyltransferases

1974