isomethyleugenol has been researched along with Breast Cancer in 285 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (3.16) | 18.7374 |
1990's | 32 (11.23) | 18.2507 |
2000's | 51 (17.89) | 29.6817 |
2010's | 132 (46.32) | 24.3611 |
2020's | 61 (21.40) | 2.80 |
Authors | Studies |
---|---|
Abd El-Wahab, MF; Abdalla, AN; Mohammed, AEI; Mohammed, HA; Ragab, EA; Shaheen, U | 1 |
Baccarani, U; Bertozzi, S; Bulfoni, M; Cedolini, C; Cesselli, D; Corradetti, B; Londero, AP; Mariuzzi, L; Marzinotto, S; Orsaria, M; Viola, L | 1 |
Braga, EA; Burdennyi, AM; Filippova, EA; Kazubskaya, TP; Loginov, VI; Lukina, SS; Pronina, IV | 1 |
Bai, J; Chen, X; Chu, S; Hou, P; Li, M; Li, Z; Qiao, S; Wang, D; Wang, P; Wang, W; Zheng, J | 1 |
Chen, L; Chen, Y; Feng, Y; Hu, F; Hu, J; Huang, C; Liu, A; Luo, X; She, X; Song, D; Sun, X; Wang, G; Wu, Q; Xu, F; Yang, X | 1 |
Gao, T; Huang, W; Huo, M; Liu, W; Teng, X; Yang, T; Yang, Y; Yin, X; Yu, H; Yuan, B; Zhang, J | 1 |
Fu, Y; Huang, X; Li, Z; Quan, Y; Tang, Q; Wang, M; Wu, A; Yang, X; Zhang, J; Zhao, P | 1 |
Hu, S; Li, C; Ye, L; Zhang, D; Zhu, C; Zhu, Q | 1 |
Jiang, G; Li, J; Li, P; Liu, G; Shen, P; Yang, H | 1 |
Curiel, T; de la Rosa, R; Hong, J; Huang, TH; Lee, JH; Liao, Y; Pechacek, D; Scheirer, J; Tan, X; Wu, Y; Xu, K; Xu, Z; Yang, M; Zhang, N; Zhang, Z | 1 |
Chen, S; Lu, YC; Pei, DS; Sun, XL; Wang, Y; Zhang, L; Zhang, LS | 1 |
Hu, C; Hu, M; Li, Z; Ma, S; Wang, M; Xiao, W; Yang, B; Zhou, M; Zhou, Q | 1 |
Klinge, CM; Petri, BJ | 1 |
Hanamura, T; Hayashida, T; Higuchi, T; Ichikawa, H; Kawamura, Y; Kubo, T; Kurozumi, S; Mukohara, T; Nagayama, A; Noguchi, E; Okazaki, M; Shimomura, A; Suto, A; Takahashi, Y; Tanaka, K; Tsuruga, A; Ushijima, T; Yamashita, S; Yoshida, M | 1 |
Bates, M; Campbell, S; Carey, LA; Considine, M; Cope, L; Fackler, MJ; Forero-Torres, A; Ingle, JN; Lin, NU; Marla, S; Nanda, R; Sokoll, L; Storniolo, AM; Sukumar, S; Tulac, S; Umbricht, CB; Venkatesan, N; Visvanathan, K; Wolff, AC; Wu, NC | 1 |
Chen, W; He, Z; Hong, Z; Ji, K; Li, S; Liu, M; Peng, X; Song, M; Xu, Y; Yang, C; Yu, J; Zhang, Q; Zhou, J; Zhu, Q; Zuo, Q | 1 |
Bonaldi, T; Buglioni, V; Di Nisio, E; Licursi, V; Mannironi, C; Negri, R; Noberini, R; Paiardini, A; Robusti, G | 1 |
Chung, HW; Hur, W; Hwang, I; Ji, MJ; Kim, S; Kim, SH; Kong, G; Moon, S; Park, HM | 1 |
Al-Moghrabi, N; Al-Showimi, M; Al-Yousef, N; AlOtai, L | 1 |
Arai, N; Ebata, T; Fujii, S; Hattori, N; Kondo, H; Liu, YY; Mukai, H; Takeshima, H; Takeuchi, C; Ushijima, T; Yamashita, S | 1 |
Gan, XL; Guan, JX; Ren, YX; Ren, ZF; Tang, LY; Wang, B; Weng, ZJ; Yang, YZ; Zhang, XF; Zhou, M | 1 |
Chen, Q; Chen, Y; Hu, Q; Li, A; Li, J; Li, L; Shen, N; Zhang, N | 1 |
Liu, X; Shen, L; Tao, J; Zeng, H; Zhai, C; Zhang, X; Zhu, Y | 1 |
Deng, X; He, YH; Hu, GS; Huang, HH; Huang, Y; Li, MY; Li, WJ; Lin, YA; Liu, W; Xie, BL; Yang, JJ; Zhang, BD; Zou, YQ | 1 |
Aydin, B; Baykal, A; Erol, T; Esendağli, G; İmamoğlu, NE; Kösemehmetoğlu, K; Taşkiran, ZE | 1 |
Andrechek, ER; Daldoul, K; Harris, LN; Hirukawa, A; Lavoie, C; Muller, WJ; Park, M; Rennhack, JP; Sanguin-Gendreau, V; Singh, S; Smith, HW; Swiatnicki, M; Varadan, V; Wang, J; Westbrook, TF; Zuo, D | 1 |
Feng, D; Gao, J; Gao, T; Hou, Y; Huang, W; Leng, S; Liu, R; Liu, W; Qiu, R; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zhang, K; Zhang, X; Zheng, Y | 1 |
Duan, D; Feng, J; Huang, B; Ji, J; Li, L; Li, Z; Lin, C; Lin, L; Liu, J; Liu, L; Lu, J; Zhang, N; Zhang, Y | 1 |
Alakwaa, FM; Savelieff, MG | 1 |
Kim, SS; Lee, MH; Lee, MO | 1 |
Liu, Y; Martinez, A; Tomita, K; Yamashita, S | 1 |
Hwang, JW; Hwang, KT; Jang, CY; Kim, NH; Kim, S; Kim, YA; Kim, YK; Myung, N; Park, JE | 1 |
Amorim, M; Antunes, L; de Sousa, SP; Fontes-Sousa, M; Henrique, R; Jerónimo, C; Lobo, J; Lobo, S; Lopes, P; Salta, S | 1 |
Feng, W; Gao, J; Hou, Y; Huang, W; Liu, W; Qiu, R; Su, D; Teng, X; Wang, Y; Yang, Y; Yi, X; Yu, H; Zhang, K; Zhang, T | 1 |
David, Y; Osunsade, A; Zheng, Q | 1 |
Deng, S; Hu, X; Li, D; Song, J; Sun, F; Tang, L; Yan, M; Yu, S | 1 |
Chan, YC; Chen, DR; Chen, Y; Hsu, KW; Liu, YE; Wang, YF; Wu, HT | 1 |
Chellamuthu, A; Gray, SG | 1 |
Caggiano, R; Di Bonito, M; Di Mauro, A; Faraonio, R; Feola, A; Gigantino, V; Porcellini, A; Romano, A; Zuchegna, C | 1 |
Huang, B; Li, H; Li, L; Liu, DX; Liu, J; Liu, L; Liu, X; Liu, Y; Lu, J; Peng, L; Wang, G; Wang, Y; Zhang, L; Zhang, Y | 1 |
Bai, J; Dong, M; Fan, D; Gao, Y; Hou, P; Huang, B; Li, H; Li, M; Li, Z; Liu, H; Lu, J; Pan, ZQ; Wang, D; Wang, Y; Zheng, J | 1 |
Bade, D; Dai, X; Gonzalez, G; Huang, M; Li, L; Liu, X; Miao, W; Sun, Y; Wang, Y; Yuan, J | 1 |
Bai, J; Chen, X; Hou, P; Li, M; Li, Z; Tang, A; Wang, D; Wang, W; Zheng, J | 1 |
Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; Arshad, A; Charles, S; Madhavan, T; Mala, K; Munusamy-Ramanujam, G; Saraswathi, NT; Singh, P | 1 |
Cao, Q; Chen, K; Cooke, JP; Gao, X; Lee, MG; Lv, J; Meng, Q; Tomoiaga, AS; Wang, G; Xia, B; Yi, Y; Zhang, L; Zhang, M; Zhao, D; Zhu, S | 1 |
Cho, JY; Kim, SW; Lee, JE; Lee, KH; Nam, AR; Schabort, JJ | 1 |
Cai, J; Chen, J; Dai, R; Gao, H; Han, JJ; Lan, F; Li, Y; Ma, H; Qu, Q; Rong, B; Song, Y; Tian, Y; Wan, J; Xie, J; Xing, S; Yan, G; Zhang, L; Zhang, Q; Zhang, W | 1 |
El-Osaily, HH; Essawi, ML; Ibrahim, IH; Salem, SM | 1 |
Emami Razavi, A; Jahangiri, R; Jamialahmadi, K; Mosaffa, F; Teimoori-Toolabi, L | 1 |
Anwar, T; Gonzalez, ME; Kleer, CG | 1 |
Sun, Y; Wang, R | 1 |
Ali, ES; Asara, JM; Ben-Sahra, I; Gao, P; Helmin, KA; O'Hara, BP; Sahu, U; Singer, BD; Villa, E | 1 |
Gao, X; He, YH; Hu, GS; Huang, HH; Huang, MF; Li, WJ; Lin, YA; Liu, W; Peng, BL; Ran, T; Xie, BL; Yang, JJ; Ye, F; Zhu, HH | 1 |
Ambrosone, CB; Chen, J; Gong, Z; Higgins, MJ; Liu, S; Wang, J | 1 |
Dank, M; Forika, G; Kiss, E; Krenacs, T; Mohacsi, R; Nemeth, Z | 1 |
Godinez-Victoria, M; Hernandez-Caballero, ME; Seseña-Mendez, E; Sierra-Ramirez, JA | 1 |
Cao, D; Ding, H; Hou, J; Huang, B; Lin, C; Liu, J; Liu, L; Liu, X; Liu, Y; Lu, J; Wang, G; Zhang, N; Zhang, X; Zhang, Y | 1 |
Abuelaish, O; Al-Balas, M; Alhesa, A; Awad, H; Azab, B; Carpenter, VJ; El-Sadoni, M; Mansour, A; Saleh, T | 1 |
Chen, C; Chen, CH; Du, G; He, Y; Jiang, D; Li, Y; Liu, R; Liu, W; Pan, J; Qiu, T; Shi, Y; Wang, X; Wu, Y; Yang, C; Zhou, J | 1 |
Hwang, SH; Jung, JH; Kim, DY; Kim, Y; Seo, D; Woo, SH; Yang, Y | 1 |
Agudo, A; Ardanaz, E; Bakker, MF; Biessy, C; Casagrande, C; Chiodini, P; Chirlaque López, MD; Clasen, J; De Bacquer, D; Ericson, U; Ferrari, P; Fortner, RT; Godderis, L; Gunter, MJ; Gylling, B; Halkjær, J; Heath, AK; Huybrechts, I; Karlsson, T; Katzke, V; Manjer, J; Masala, G; Muller, D; Nicolas, G; Overvad, K; Pala, V; Papadimitriou, N; Sacerdote, C; Sánchez, MJ; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Van Herck, K; Van Puyvelde, H; Weiderpass, E | 1 |
Ball, LE; Brobbey, C; Gan, W; Liu, L; Olsen, SK; Ostrowski, MC; Palanisamy, V; Yin, S | 1 |
Chen, C; Chen, L; Chen, Y; Huang, A; Khan, NUH; Li, Z; Mao, M; Wang, J; Wang, L; Xie, S; Yang, J; Zhang, X; Zhou, J; Zhou, Y | 1 |
Liu, Y; Ou, B; Xu, X; Yan, Y; Yang, X; Zhang, J | 1 |
Coon, JJ; Hebert, AS; Kwiecien, NW; Liu, F; Shishkova, E; Xu, W; Zeng, H | 1 |
Liu, L; Shen, H; Wang, Y | 1 |
Borges, CR; Hu, Y | 1 |
Bernard-Gallon, D; Bignon, YJ; Dagdemir, A; Judes, G; Karsli-Ceppioglu, S; Lebert, A; Penault-Llorca, F | 1 |
Ceccaldi, R; D'Andrea, AD; Duarte, AA; Gogola, E; Jonkers, J; Konstantinopoulos, PA; Rondinelli, B; Rottenberg, S; van de Ven, M; van der Sluijs, R; Yücel, H | 1 |
An, K; Chang, S; Du, F; Han, X; Li, G; Liu, Z; Ma, W; Sun, Y; Wang, D; Wang, J; Wang, X; Yang, C; Yu, H; Zhang, Y; Zhang, Z; Zhao, Z | 1 |
Freitas, MA; Holt, MV; Hoover, ME; Jiang, T; Marshall, AG; Young, NL | 1 |
Dou, Y; Guo, X; Li, D; Li, P; Ma, C; Qiu, L; Wang, D; Wu, J; Yi, J; Yin, Y | 1 |
Feng, D; Gao, J; Hou, Y; Huang, W; Leng, S; Liu, R; Qiu, R; Shi, H; Sun, G; Teng, X; Wang, S; Wang, Y; Yang, Y; Yu, W; Zeng, Y; Zheng, Y | 1 |
An, W; Jeong, D; Kim, J; Kim, K; Kim, M; Koh, J; Lee, S; Lu, JF; Punj, V; Shin, H; Shin, Y; Ulmer, TS | 1 |
Cantu, EJ; Forester, SC; Grimes, KL; Kaur, B; McCarthy, JJ; Stuart, CM | 1 |
Ham, J; Jeong, D; Kim, SJ; Lee, H; Lee, S; Park, S | 1 |
Chen, T; Han, X; Ren, G; Tang, J | 1 |
Han, D; Li, X; Lu, J; Ma, M; Ma, Y; Tan, J; Wang, Y; Xu, G; Yao, R; Zhao, Y | 1 |
Dowhan, DH; Muscat, GEO; Wang, SM | 1 |
Arienti, C; Bacalini, MG; Bonafè, M; De Carolis, S; Fabbri, F; Ferracin, M; Franceschi, C; Garagnani, P; Gensous, N; Latini, S; Marasco, E; Mensà, E; Olivieri, F; Papi, A; Salvioli, S; Santi, S; Sarnelli, A; Storci, G; Tesei, A; Zanoni, M | 1 |
Choucair, A; Corbo, L; Jacquemetton, J; Kassem, L; Le Romancer, M; Marangoni, E; Omarjee, S; Pham, TH; Rambaud, J; Trédan, O; Treilleux, I | 1 |
Chen, Y; Guo, C; Jin, L; Pan, Y; Shen, Y; Shi, W; Tang, T; Wang, Y; Wu, Y; Xia, T; Xing, Y; Yin, X; Zhang, Y | 1 |
Christensen, BC | 1 |
Liu, W; Ning, J; Wu, D; Wu, L; Zhang, D | 1 |
Cheng, MB; Fan, XZ; Liu, LM; Sun, WZ; Xu, YL; Zhang, Y | 1 |
Dong, X; Donohoo, KB; Mechref, Y; Peng, W; Tang, H; Yu, CY; Zhou, S | 1 |
Carmalt, H; Chan, B; Cooper, CL; Karim, RZ; Lee, CS; Mak, C; O'Toole, SA; Putti, TC; Scolyer, RA; Selinger, C; Tan, PH; Tse, GM; Yu, B | 1 |
Chen, Y; Cui, X; Hu, H; Jiao, Y; Li, S; Lin, L; Lv, X; Song, E; Wang, M; Yao, H; Yu, F | 1 |
Cortez, V; Mann, M; Vadlamudi, R | 1 |
Abbondanza, C; Avvedimento, EV; Di Santi, A; Migliaccio, A; Ombra, MN; Perillo, B | 1 |
Hieda, M; Higashi, S; Kimura, H; Matsumoto, A; Matsuura, N; Matsuura, S; Mori, M; Nishioka, Y; Yamamoto, H; Yokoyama, Y | 1 |
Alley, WR; Novotny, MV | 2 |
Han, X; Huangyang, P; Jia, H; Shang, Y; Sun, L; Yan, R; Yang, X; Yu, N | 1 |
Falahi, F; Hospers, GA; Huisman, C; Kazemier, HG; Kok, K; Rots, MG; van der Vlies, P | 1 |
Benevolenskaya, EV; Jene-Sanz, A; Khramtsov, AI; Khramtsova, GF; Lopez-Bigas, N; Olopade, OI; Váraljai, R; Vilkova, AV | 1 |
Choi, HK; Choi, HS; Khanal, P; Kim, G; Lee, KY; Lim, SC; Yun, HJ | 1 |
Albaret, MA; Belin, S; Bourdon, JC; Bouvet, P; Catez, F; Cong, R; Diaz, JJ; Ghayad, SE; Hacot, S; Jordan, L; Marcel, V; Mertani, HC; Morel, AP; Prats, AC; Puisieux, A; Saurin, JC; Solano-Gonzàlez, E; Tafer, Y; Therizols, G; Thompson, A; Vendrell, JA | 1 |
Chan, CH; Dhar, SS; Gu, B; Kim, JH; Lee, MG; Lee, SH; Lin, HK; Sharma, A | 1 |
Barton, MC; Jiang, S; Li, B; Li, H; Li, W; Li, Y; Peng, D; Ren, Y; Shi, X; Stratton, S; Tanaka, K; Wen, H; Wu, J; Xi, Y; Xia, Z | 1 |
Bachelot, T; Billaud, M; Bouchekioua-Bouzaghou, K; Chabaud, S; Corbo, L; Dayan, G; Hussein, N; Lavergne, E; Le Romancer, M; Mader, S; Poulard, C; Rambaud, J; Treilleux, I | 1 |
Hu, C; Jiang, F; Li, Y; Li, Z; Mu, J; Ning, S; Si, L; Wang, X; Ye, X | 1 |
Chung, HH; Lin, VC; Sun, Y; Woo, AR | 1 |
Davidson, NE; Harrington, E; Huang, Y; Katz, TA; Oesterreich, S; Vasilatos, SN | 1 |
Hamada, M; Hieda, M; Kimura, H; Matsumoto, A; Matsuura, N; Nishioka, Y; Ogihara, E; Shinchi, Y; Tsujimoto, M; Yokoyama, Y; Yoshidome, K | 1 |
Cebrian, ME; Gandolfi, AJ; Hernández-Ramírez, RU; López-Carrillo, L; Ornelas-Aguirre, JM; Torres-Sánchez, L | 1 |
Chan, TA; Drobnjak, M; Giri, D; Kannan, K; Lee, W; Reyngold, M; Turcan, S; Vahdat, LT; Viale, A; Walsh, LA | 1 |
Bodine, DM; Crawford, NP; Dworkin, AM; Gildea, D; Lee, M; Lichtenberg, J; Patel, SJ; Trivedi, NS | 1 |
Gu, XT; He, DX; Jiang, L; Jin, J; Ma, X | 1 |
Beck, AH; Collins, LC; Hazra, A; Healey, MA; Hu, R; Schnitt, SJ; Tamimi, RM | 1 |
Chelala, C; Cutts, RJ; Dayem Ullah, AZ; Gadaleta, E; Guerra-Assunção, JA | 1 |
Brown, K; Deng, C; Huang, S; Pampo, C; Qiu, Y; Salz, T; Siemann, D | 1 |
Gaforio, JJ; López-Biedma, A; Sánchez-Quesada, C | 1 |
Brambert, PR; Calafiore, G; Desai, CV; Godley, LA; Hameed, R; Kelpsch, DJ; Raimondi, SL | 1 |
Anjanappa, M; Appaiah, HN; Badve, S; Bhat-Nakshatri, P; Crooks, PA; Gilley, D; Mathews, W; Nakshatri, H; Sweeney, C; Tanaka, H | 1 |
Abdel-Hafiz, HA; Horwitz, KB | 1 |
Birchmeier, W; Grosskopf, S; Györffy, B; Holland, JD; Lan, L; Qi, J; Rademann, J; Vogel, R; Wulf-Goldenberg, A | 1 |
Chen, KM; Chitale, D; Datta, I; Divine, G; Worsham, MJ | 1 |
Li, C; Li, X; Liu, L; Sun, L; Xia, W; Yu, Y; Zhang, Y | 1 |
Bahar, I; Fujita, N; Gamper, A; Gur, M; Hu, D; Hung, MC; Lan, L; Wan, Y; Zhou, Z | 1 |
Hu, F; Li, M; Li, ZB; Liu, XH; Yang, FH; Zhong, Y; Zhou, J; Zhou, L | 1 |
Kong, G; Lee, JY | 1 |
Davidson, B; Falnes, PØ; Jakobsson, ME; Moen, A | 1 |
Bonaldi, T; Minucci, S; Noberini, R; Pruneri, G; Uggetti, A | 1 |
Fu, L; Gu, F; Ma, Y; Qin, F; Zhang, J | 1 |
Gu, H; Jia, X; Lee, KA; Levy, T; Ren, JM; Rikova, K; Silva, JC; Stokes, MP; Yang, V | 1 |
Hur, W; Hwang, JT; Jeong, JC; Kang, MR; Kim, EJ; Kwon, YS; Park, JH; Park, UH; Song, BJ; Um, SJ; Yoon, SK | 1 |
Ishimura, A; Oktyabri, D; Suzuki, T; Tange, S; Terashima, M | 1 |
Feng, Q; Gao, T; Lei, Q; Shi, Y; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, M; Yang, F; Ye, T; You, X; Yu, L; Zhang, L; Zhu, Y | 1 |
Bullen, JW; Chen, I; He, X; Lu, H; Samanta, D; Semenza, GL; Zhang, C; Zhang, H | 1 |
Lei, PJ; Li, L; Li, YM; Wang, HY; Wei, G; Wu, M; Ye, M; Zhang, X; Zhao, J; Zhao, QY; Zheng, JY | 1 |
Cabezas-Herrera, J; González-Guerrero, R; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sánchez-del-Campo, L | 1 |
Guo, G; Ramadoss, S; Wang, CY | 1 |
Chen, H; Gupta, V; Lorton, B; Shechter, D | 1 |
Bradner, J; Brown, M; Cheng, H; Dreijerink, KM; Groner, AC; Lin, CY; Ohlson, CE; Reyes, J; Roberts, TM; Spangle, JM; Zhao, JJ | 1 |
Bernard-Gallon, D; Bignon, YJ; Dagdemir, A; Echegut, M; Judes, G; Karsli-Ceppioglu, S; Lebert, A; Ngollo, M; Penault-Llorca, F | 1 |
Chen, YM; Fu, PF; Liu, Y; Lv, KZ; Wei, HY | 1 |
Lin, MZ; Liu, SL; Sui, YF | 1 |
Cebrián, ME; Hernández-Alcaraz, C; Hernández-Ramírez, RU; López-Carrillo, L; Pineda-Belmontes, CP | 1 |
Chan, NL; Chen, YJ; Kuo, WH; Lin, MC; Teng, SC; Tsai, CH; Tzeng, SR; Wu, IC; Wu, KJ; Yu, CJ | 1 |
Chen, I; Gabrielson, E; Lu, H; Samanta, D; Semenza, GL; Zhang, C; Zhi, WI | 1 |
Kim, HP; Kim, M; Lee, JJ | 1 |
Dong, W; Jia, L; Li, N; Ma, X; Miao, Y; Su, Z; Zhao, L; Zhou, H | 1 |
Bonnamy, PJ; Bouakka, M; Hanoux, V; Vanneste, M | 1 |
Chakravarti, D; Chen, JR; Chen, P; Deng, P; DePinho, RA; Dey, P; Lan, Z; Li, J; Liang, X; Liao, W; Lu, X; Navone, NM; Shah, S; Shang, X; Spring, DJ; Tang, M; Troncoso, P; Wang, G; Wang, YA; Zhang, J; Zhao, D | 1 |
Geng, P; Huang, B; Li, Y; Li, Z; Lin, C; Liu, DX; Liu, X; Liu, Y; Lu, J; Tan, J; Wang, G; Yan, X; Zhang, N; Zhang, Y | 1 |
Brown, M; Chi, D; Cook, J; de Laat, W; Dreijerink, KMA; Font-Tello, A; Groner, AC; Gu, L; Lim, E; Lin, CY; Long, HW; Rao, PK; Reyes, J; Vos, ESM | 1 |
Bouchekioua-Bouzaghou, K; Corbo, L; Gobert-Gosse, S; Goddard, S; Le Romancer, M; Leconte, N; Robin-Lespinasse, Y; Sentis, S; Treilleux, I | 1 |
Kagey, JD; Kapoor-Vazirani, P; Powell, DR; Vertino, PM | 1 |
Domann, FE; Hitchler, MJ; Oberley, LW | 1 |
Huang, TH; Lin, S; Potter, DP; Yan, P | 1 |
Ateeq, B; Brenner, JC; Cao, Q; Cao, X; Chinnaiyan, AM; Han, B; Jing, X; Kim, JH; Kumar-Sinha, C; Laxman, B; Lonigro, RJ; Maher, CA; Mani, RS; Palanisamy, N; Ramnarayanan, K; Shankar, S; Tan, P; Varambally, S; Wang, X; Yu, J | 1 |
Albericio, F; Bayó-Puxan, N; Marcucci, E; Prats-Alfonso, E; Tulla-Puche, J | 1 |
Krupitza, G; Mader, RM; Schmidt, WM; Steger, GG | 1 |
Abdelghany, MK; Ahmed, RA; Ammar, AA; Ball, GR; Collins, HM; Ellis, IO; Elsheikh, SE; Garibaldi, JM; Grainge, MJ; Green, AR; Heery, DM; Martinez-Pomares, L; Paish, CE; Powe, DG; Rakha, EA; Soria, D | 1 |
Clark, SJ; Hinshelwood, RA; Huschtscha, LI; Melki, JR; Paul, C; Reddel, RR; Song, JZ; Stirzaker, C | 1 |
An, W; Choi, J; Heo, K; Kim, H; Kim, JH; Kim, K | 1 |
Bebenek, M; Lu, A; Mann, M; Pudełko, M; Wiśniewski, JR; Ziółkowski, P; Zougman, A | 1 |
Casey, PJ; Cushman, I | 1 |
Arnason, TG; Davies, GF; Harkness, TA; Juurlink, BH; Ross, AR | 1 |
Beghin, A; Belin, S; Bezin, L; Brunet-Manquat, S; Diaz, JJ; Dumontet, C; Mertani, HC; Prats, AC; Solano-Gonzàlez, E; Textoris, J | 1 |
Amagai, T; Kuruto, R; Ohura, T; Sakakibara, H; Shimoi, K; Takemura, H; Uchiyama, H | 1 |
Chan, E; Marquez, VE; Sun, F; Wu, Z; Yang, X; Yu, Q | 1 |
Chen, L; Chen, Y; Di, GH; Jin, W; Shao, ZM; Wu, J; Xu, SG; Yin, WJ | 1 |
Bommi, PV; Dimri, GP; Dimri, M; Khandekar, JD; Sahasrabuddhe, AA | 1 |
Cavaillès, V; Corbo, L; Jalaguier, S; Le Romancer, M; Sentis, S; Teyssier, C | 1 |
Becker, A; Buettner, R; Janzer, A; Kirfel, J; Lim, S; Schüle, R; Zimmer, A | 1 |
Bystricky, K; Dalvai, M | 1 |
Dou, QP | 1 |
Argani, P; Brzoska, P; Chang, HY; Gupta, RA; Horlings, HM; Hung, T; Kim, J; Kong, B; Li, R; Rinn, JL; Shah, N; Sukumar, S; Tsai, MC; van de Vijver, MJ; Wang, KC; Wang, Y; West, RB; Wong, DJ | 1 |
Alley, WR; Madera, M; Mechref, Y; Novotny, MV | 1 |
Bassett, E; Bazarov, AV; Beliveau, A; Benhattar, J; Campeau, E; Campisi, J; Chicas, A; Hines, WC; Lee, L; Lee, WJ; Lowe, SW; Melodyev, S; Mukhopadhyay, R; Ren, B; Rodier, F; Van Sluis, M; Yaswen, P; Zaslavsky, Y | 1 |
Carpio, L; Guendel, I; Kashanchi, F; Kehn-Hall, K; Pedati, C; Schwartz, A; Teal, C | 1 |
Bonaldi, T; Cuomo, A; Minucci, S; Moretti, S | 1 |
Breiling, A; Croce, CM; de Souza Rocha Simonini, P; Diederichs, S; Gupta, N; Hoheisel, JD; Lyko, F; Malekpour, F; Malekpour, M; Mayer, D; Najmabadi, H; Omranipour, R; Riazalhosseini, Y; Sahin, O; Volinia, S; Youns, M | 1 |
Akdemir, KC; Aronow, B; Barton, MC; Fischle, W; Gozani, O; Hung, MC; Patel, DJ; Plunkett, W; Schwarzer, D; Shi, X; Tsai, CY; Tsai, WW; Wang, Z; Winter, S; Xia, W; Yiu, TT | 1 |
Alberio, R; Allegrucci, C; Dixon, JE; Johnson, AD; Kumari, R; Rushton, MD; Shah, M; Sottile, V; Watson, S | 1 |
Boric, L; Davidson, NE; Huang, Y; Shaw, PG; Vasilatos, SN | 1 |
Dong, Z; Du, J; Huang, B; Jiang, H; Kong, C; Li, L; Lu, J; Ou, Z; Shao, Z; Zhang, Y; Zhu, S | 1 |
Han, X; Li, Q; Li, Y; Liang, J; Shang, Y; Shi, L; Sun, L; Xuan, C; Yang, X; Yao, Z; Yi, X; Yu, W; Zhang, Y | 1 |
Li, W; Matsumura, F; Vogel, CF; Wong, P; Wu, D | 1 |
Flockhart, DA; Huang, TH; Huang, Y; Li, L; Liu, Y; Nephew, KP; Shen, C; Skaar, TC; Teng, M; Wang, G; Wang, Y; Wang, Z; Yan, P; Zhao, Y | 1 |
Cohen, P; Corbo, L; Le Romancer, M; Poulard, C; Renoir, JM; Sentis, S | 1 |
Gui, B; Han, X; Li, Q; Shang, Y; Shi, L; Wang, J; Yao, Z; Yu, W; Zhang, D | 1 |
Haendler, B; Stratmann, A | 1 |
Ciappio, ED; Crott, JW; Mason, JB | 1 |
Das, PM; Huynh, FC; Jones, FE; Mitra, D | 1 |
Alam, N; Bhattacharya, N; Mukherjee, N; Panda, CK; Roy, A; Roychoudhury, S | 1 |
Davidson, NE; Huang, Y; Jankowitz, R; Nayak, S; Oesterreich, S | 1 |
Beland, FA; Pogribny, IP; Simpson, NE; Tryndyak, VP | 1 |
Dou, Y; Du, Z; Katoh, H; Li, W; Li, X; Liu, CG; Liu, R; Liu, X; Liu, Y; Lyons, R; Qin, ZS; Wang, L; Wu, L; Zheng, P | 1 |
Pan, YX; Rollet, M; Yang, K; Zheng, S | 1 |
Hennighausen, L; Yoo, KH | 1 |
Berg, CD; Boyd-Morin, J; Buys, SS; Fuhrman, BJ; Gail, MH; Hoover, RN; Isaacs, C; Keefer, LK; Schairer, C; Sue, LY; Veenstra, TD; Xu, X; Ziegler, RG | 1 |
Choe, MK; Hong, CP; Park, J; Roh, TY; Seo, SH | 1 |
Dong, C; Evers, BM; Rychahou, PG; Wang, Y; Wu, Y; Yao, J; Yu, Y; Zhou, BP | 1 |
Bittencourt, D; Chodankar, R; Purcell, DJ; Stallcup, MR; Won Jeong, K | 1 |
Greer, SF; Thakkar, M; Truax, AD | 1 |
Bensimon, J; Bertrand, P; Chevalier, F; Chevillard, S; Depagne, J; Hem, S; Lebeau, J | 1 |
Chen, H; Jin, F; Liu, C; Mao, XY; Wang, H; Wei, J; Yao, F; Zheng, HC | 1 |
Aradottir, S; Bendahl, PO; Borg, Å; Ethier, SP; Fernö, M; Grabau, D; Gruvberger-Saal, S; Hegardt, C; Holm, K; Howlin, J; Lövgren, K; Malmström, P; Ringnér, M; Rydén, L; Saal, LH; Stål, O | 1 |
Bobowski, M; Cazet, A; Colomb, F; Delannoy, P; Guérardel, Y; Le Bourhis, X; Rombouts, Y; Steenackers, A; Vanbeselaere, J | 1 |
Kong, HK; Park, JH; Yoon, S | 1 |
Ford, M; Hu, CY; Kleer, CG; Li, XY; Weiss, SJ; Wu, ZQ | 1 |
Kang, KW; Kim, SK; Kwak, HC; Lee, JY; Oh, SJ; Phuong, NT; Ryu, CS | 1 |
Liang, X; Liu, T; Liu, XS; Liu, Y; Ma, Y; Niu, M; Pang, D; Ren, Y; Shan, M; Song, Q; Sun, Q; Sun, S; Wei, W; Xia, B; Yang, L; Yang, Y; Zhang, G; Zhang, X; Zhang, Y | 1 |
Davidson, NE; Huang, Y; Katz, TA; Oesterreich, S; Vasilatos, SN; Wan, Y | 1 |
Abdelghany, MK; Aslam, A; Collins, HM; Deeves, SE; Heery, DM; Kindle, KB; Kundu, TK; Mantelingu, K; Messmer, M; Winkler, GS; Yue, B | 1 |
Chow, LW; Hu, XC; Loo, WT | 1 |
Zhu, BT | 1 |
Badawi, AF; Cavalieri, EL; Devanesan, PD; Edney, JA; Higginbotham, SM; Meza, JL; Rogan, EG; West, WW | 1 |
Bolton, JL; Chang, M; Li, Y; Mesecar, AD; Nikolic, D; van Breemen, RB; Yager, JD; Yao, J; Yu, L | 1 |
Bais, AJ; Callen, DF; Gardner, AE; Kremmidiotis, G; McKenzie, OL; Sutherland, GR | 1 |
Clarke, S; Frankel, A; Gutmann, DH; Herschman, HR; Jiang, W; Miranda, TB; Newsham, IF; Robb, VA; Roemer, ME; Singh, V | 1 |
Gaiger, A; Grunt, TW; Kainz, B; Puckmair, K; Tomek, K | 1 |
Baker, JC; Bean, GR; Bowie, ML; Broadwater, G; Fabian, CJ; Kimler, BF; Marcom, PK; Ratliff-Daniel, B; Scott, V; Seewaldt, VL; Seo, P; Slade, J; Troch, MM; Wilke, LG; Yee, L; Zalles, CM | 1 |
Douglas-Jones, A; Jiang, WG; Lee-Jones, L; Mansel, RE; Martin, TA; Mokbel, K; Sampson, J; Watkins, G | 1 |
Jiang, W; Newsham, IF | 1 |
Chow, LW; Loo, WT; Lui, EL; Zhu, L | 1 |
Aozasa, K; Hasegawa, JI; Ikeda, JI; Kim, YK; Kimura, H; Miyoshi, Y; Morii, E; Nishida, T; Noguchi, S; Takakuwa, T; Tomita, Y | 1 |
Birgisdottir, V; Bodvarsdottir, SK; Eyfjord, JE; Hilmarsdottir, H; Jonasson, JG; Stefansson, OA | 1 |
Bunker, CH; Okobia, MN | 1 |
Corbo, L; Kolytcheff, C; Le Romancer, M; Robin-Lespinasse, Y; Rostan, MC; Sentis, S | 1 |
Anania, FA; Saxena, NK; Sharma, D; Vertino, PM | 1 |
Chen, W; Jiang, X; Karuturi, RK; Lee, PL; Liu, ET; Tan, J; Tan, PB; Yang, X; Yu, Q; Zhuang, L | 1 |
Wang, Y; Zou, Y | 1 |
Andrews, LG; Berletch, JB; Katiyar, SK; Liu, C; Love, WK; Tollefsbol, TO | 1 |
Cottingham, K | 1 |
Goetz, JA; Kang, P; Kyselova, Z; Mechref, Y; Novotny, MV | 1 |
Chiffer, RC; Leuba, SH; Rodriguez-Collazo, P; Smith, CL; Snyder, SK; Zlatanova, J | 1 |
Dobrovic, A; Krypuy, M; Loughrey, MB; Snell, C; Wong, EM | 1 |
Asim, M; Basir, SF; Chauhan, M; Deo, SS; Husain, SA; Hussain, A; Kukreti, H; Naqvi, RA; Pasha, ST; Sarin, R; Saxena, A; Shukla, NK | 1 |
Hui, Y; Liu, MC; Liu, MY; Wu, YY; Yasuda, S | 1 |
Cheng, X; Collins, RE; Jia, D; Kapoor-Vazirani, P; Peng, J; Powell, DR; Sharma, D; Subramanian, K; Vertino, PM | 1 |
Dobrolecki, LE; Goetz, JA; Hickey, RJ; Kang, P; Kyselova, Z; Malkas, LH; Mechref, Y; Novotny, MV; Schnaper, L; Sledge, GW | 1 |
Erb, N; Heller-Schöch, G; Lorenz, H; Müller, J; Schöch, G; Winkler, K | 1 |
Bowen, J; Cailleau, RM; Knesek, JE; Kuo, MT; Sen, S; Teeter, L | 1 |
Cline, MJ; deKernion, JB; Slamon, DJ; Verma, IM | 1 |
Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG | 1 |
Cardillo, MR; Frati, L; Gulino, A; Lubrano, C; Petrangeli, E; Ravenna, L; Salvatori, L; Sciarra, F; Vacca, A | 1 |
Baylin, SB; Biel, MA; Cavenee, WK; el Deiry, W; Issa, JP; Kuerbitz, SJ; Nelkin, BD; Wales, MM | 1 |
Baylin, SB; Chopra, H; Davidson, NE; Graff, JR; Herman, JG; Isaacs, WB; Jarrard, DF; Lapidus, RG; Pitha, PM; Xu, R | 1 |
Baird, WM; Boyd, GW; Coombs, MM | 1 |
Dante, R; Martin, V; Ribieras, S; Rio, MC; Song-Wang, X | 1 |
Keydar, I; Weiss, M; Wreschner, DH; Zrihan-Licht, S | 1 |
Dorssers, LC; Foekens, JA; van Agthoven, T; van Agthoven, TL | 1 |
Dante, R; Frappart, L; Lointier, P; Martin, V; Ribieras, S; Song-Wang, XG | 1 |
Christou, M; Gierthy, JF; Hayes, CL; Jefcoate, CR; Spink, DC; Sutter, TR; Young, NR | 1 |
Imaoka, S; Inaji, H; Koyama, H; Motomura, K; Noguchi, S | 1 |
Aihara, T; Inaji, H; Koyama, H; Motomura, K; Noguchi, S | 1 |
Benz, CC; Daniel, JC; Kabat, D; Maki, RA; Scott, GK; Xiong, X | 1 |
Baylin, SB; Davidson, NE; Issa, JP; Ottaviano, YL; Parl, FF; Smith, HS | 1 |
Buchhagen, DL; Etkind, P; Qiu, L | 1 |
London, WP | 1 |
Eppenberger, U; Heizmann, CW; Mueller, H; Pedrocchi, M; Schäfer, BW | 1 |
Favre, B; Hemmings, BA; Turowski, P; Zolnierowicz, S | 1 |
Baylin, SB; Herman, JG; Jen, J; Merlo, A | 1 |
Ainsworth, P; Andrews, J; Chakraborty, P; Lopes, E; Mancini, D; Rodenhiser, D; Singh, S | 1 |
Bittman, R; Marino-Albernas, JR; Mayhew, E; Peters, A | 1 |
Abad-Hernández, MM; Cruz-Hernández, JJ; Dueñas-González, A; González-Sarmiento, R | 1 |
Davidson, NE; Ferguson, AT; Lapidus, RG | 1 |
Keller, WL; Park, CS; Wu, D | 1 |
Ando, Y; Hara, Y; Iwase, H; Iwata, H; Kobayashi, S; Omoto, Y | 1 |
Curran, EM; Huang, TH; Laux, DE; Lubahn, DB; Welshons, WV | 1 |
Hayashi, S; Yoshida, T | 1 |
Fearon, ER | 1 |
Baylin, SB; Bonilla, F; Bussaglia, E; Dominguez, G; Esteller, M; Gabrielson, E; Harkes, IC; Herman, JG; Lerma, E; Matias-Guiu, X; Prat, J; Repasky, EA; Schutte, M; Silva, JM | 1 |
Deckers, GH; Kloosterboer, HJ; Schoonen, WG | 1 |
Grushko, T; Olopade, OI | 1 |
Deshmane, VH; Fentiman, IS; Hart, IR | 1 |
Dawling, S; Mernaugh, RL; Parl, FF; Roodi, N; Wang, X | 1 |
Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
Fohr, I; Pietrzik, K; Prinz-Langenohl, R | 1 |
Levine, L; Stolbach, L; Waalkes, TP | 1 |
Bianchi, MS; Bianchi, NO; Bolzán, AD | 1 |
Huang, AT; Liu, YH; Panella, TJ; Teng, CT | 1 |
Bock, KW; Köchel, H; Marx, D; Münzel, P; Schauer, A | 1 |
Alvisi, A; del Senno, L; Hanau, S; Kumar, VL; Maestri, I; Piva, R; Rimondi, AP | 1 |
Chevchenko, VE; Levtshuk, AA; Lifanova, YE; Maximovitch, DM; Zaridze, DG | 1 |
Chamness, GC; Cheah, MS; Falette, NS; Fuqua, SA; Greene, GL; McGuire, WL | 1 |
Gregory, P; Wang, N | 1 |
Davidson, NE; Gelmann, EP; Kasid, A; Lippman, ME | 1 |
Kaysen, J; Kufe, D; Spriggs, D | 1 |
Bhavanandan, VP; Davidson, EA; Gowda, DC | 1 |
Eppenberger, U; Löser, R; Seibel, K | 1 |
19 review(s) available for isomethyleugenol and Breast Cancer
Article | Year |
---|---|
m6A readers, writers, erasers, and the m6A epitranscriptome in breast cancer.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Breast Neoplasms; Female; Humans; Methylation; Methyltransferases; RNA; RNA-Binding Proteins; RNA, Messenger | 2023 |
The RNA Methyltransferase NSUN2 and Its Potential Roles in Cancer.
Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Colorectal Neoplasms; Female; Humans; Lung Neoplasms; Methylation; Methyltransferases; Mice; Phylogeny; RNA, Messenger | 2020 |
Noncanonical Functions of the Polycomb Group Protein EZH2 in Breast Cancer.
Topics: Breast Neoplasms; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Lysine; Methylation | 2021 |
Epigenetic arginine methylation in breast cancer: emerging therapeutic strategies.
Topics: Animals; Arginine; Breast Neoplasms; Epigenesis, Genetic; Female; Humans; Methylation | 2019 |
Recent insights into the molecular pathogenesis of mammary phyllodes tumours.
Topics: Breast Neoplasms; Chromosome Aberrations; Comparative Genomic Hybridization; Female; Humans; Immunohistochemistry; Loss of Heterozygosity; Methylation; Mutation; Phyllodes Tumor; Transcriptome | 2013 |
Structural glycomic analyses at high sensitivity: a decade of progress.
Topics: Breast Neoplasms; Carbohydrates; Electrophoresis, Capillary; Female; Glycomics; Glycoproteins; Humans; Isotope Labeling; Methylation; N-Acetylneuraminic Acid; Oligosaccharides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2013 |
Role of epigenetic modifications in luminal breast cancer.
Topics: Breast Neoplasms; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; MicroRNAs | 2015 |
Function of Slit/Robo signaling in breast cancer.
Topics: beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Genes, Tumor Suppressor; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Methylation; Nerve Tissue Proteins; Receptors, Immunologic; Signal Transduction | 2015 |
Protein arginine methylation in estrogen signaling and estrogen-related cancers.
Topics: Animals; Arginine; Breast Neoplasms; Estrogens; Female; Humans; Male; Methylation; Models, Biological; Neoplasms; Protein-Arginine N-Methyltransferases; Receptors, Estrogen; Signal Transduction | 2010 |
The role of histone modifications and variants in regulating gene expression in breast cancer.
Topics: Acetylation; Animals; Breast Neoplasms; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; Histone Acetyltransferases; Histone Deacetylases; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Isoenzymes; Methylation; Protein-Arginine N-Methyltransferases | 2010 |
Cracking the estrogen receptor's posttranslational code in breast tumors.
Topics: Acetylation; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Estrogens; Female; Humans; Methylation; Mutation; Phosphorylation; Protein Processing, Post-Translational; Receptors, Estrogen; Signal Transduction; Ubiquitination | 2011 |
Maternal one-carbon nutrient intake and cancer risk in offspring.
Topics: Animals; Breast Neoplasms; Colorectal Neoplasms; DNA Methylation; Female; Humans; Male; Maternal Nutritional Physiological Phenomena; Methylation; Pregnancy; Risk Factors; Vitamin B Complex; Vitamin B Deficiency | 2011 |
Epigenetics in breast cancer: what's new?
Topics: Acetylation; Animals; Breast Neoplasms; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Histones; Humans; Methylation | 2011 |
EZH2 methyltransferase and H3K27 methylation in breast cancer.
Topics: Animals; Breast Neoplasms; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Histones; Humans; Methylation; Mice; Models, Genetic; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Repressor Proteins; Signal Transduction; Transcription Factors | 2012 |
Estrogen metabolism and breast cancer risk--a review.
Topics: Animals; Aromatase; Breast Neoplasms; Cytochrome P-450 Enzyme System; Disease Susceptibility; Estrogens; Female; Humans; Hydroxylation; Methylation; NADP; Polymorphism, Genetic; Risk | 2006 |
The regulation of estrogen receptor expression and function in human breast cancer.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; CpG Islands; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogens; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Loss of Heterozygosity; Methylation; Mutation; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Receptors, Estrogen; RNA Splicing; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic | 1998 |
Genetic and epigenetic alterations of the estrogen receptor gene and hormone independence in human breast cancer.
Topics: Alternative Splicing; Breast Neoplasms; DNA, Neoplasm; Female; Gene Deletion; Gene Rearrangement; Humans; Methylation; Mutation; Neoplasms, Hormone-Dependent; Receptors, Estrogen; RNA, Neoplasm | 1998 |
[Regulation of ER(estrogen receptor) gene expression in the genesis and development of breast cancer].
Topics: Breast Neoplasms; DNA; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Promoter Regions, Genetic; Receptors, Estrogen; Transcription, Genetic | 2000 |
Beneficial role for folate in the prevention of colorectal and breast cancer.
Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Female; Folic Acid; Homocysteine; Humans; Methylation; Prospective Studies; Risk Factors | 2001 |
2 trial(s) available for isomethyleugenol and Breast Cancer
Article | Year |
---|---|
Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell-Free Nucleic Acids; Disease Progression; Female; Humans; Liquid Biopsy; Methylation | 2023 |
Retinoic acid receptor-beta2 promoter methylation in random periareolar fine needle aspiration.
Topics: Adult; Aged; Breast Neoplasms; Carcinogenicity Tests; Female; Humans; Methylation; Middle Aged; Postmenopause; Premenopause; Receptors, Retinoic Acid; Risk Factors | 2005 |
264 other study(ies) available for isomethyleugenol and Breast Cancer
Article | Year |
---|---|
Isolation, Characterization, Complete Structural Assignment, and Anticancer Activities of the Methoxylated Flavonoids from
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Colonic Neoplasms; Female; Flavonoids; HCT116 Cells; Humans; MCF-7 Cells; Methylation; Plant Extracts; Rhamnus | 2021 |
TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: a retrospective study.
Topics: Aged; Aged, 80 and over; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Beclin-1; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Homeobox Protein PITX2; Homeodomain Proteins; Humans; Immunohistochemistry; Methylation; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Prognosis; Protein-Arginine N-Methyltransferases; Receptor, ErbB-2; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Time Factors; Tissue Array Analysis; Transcription Factors | 2021 |
Relationship of the Levels of microRNA Gene Methylation with the Level of Their Expression and Pathomorphological Characteristics of Breast Cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Methylation; MicroRNAs; Neoplasm Staging; Receptor, ErbB-2 | 2021 |
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Humans; Methylation; Mice; Mice, Nude; Phosphorylation; Protein-Arginine N-Methyltransferases | 2021 |
EZH2-triggered methylation of SMAD3 promotes its activation and tumor metastasis.
Topics: Breast Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Phosphorylation; Signal Transduction; Smad3 Protein | 2022 |
The hub ten gene-based risk score system using RNA m
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Methylation; Risk Factors; RNA; Tumor Microenvironment | 2022 |
Bioinformatics Analysis of the Characteristics and Correlation of m6A Methylation in Breast Cancer Progression.
Topics: Adenosine; Breast Neoplasms; Computational Biology; Female; Humans; Methylation; RNA | 2022 |
Comprehensive Analysis of the Expression and Prognostic Value of LMAN2 in HER2+ Breast Cancer.
Topics: Adenosine; Breast Neoplasms; Female; Humans; Mannose-Binding Lectins; Membrane Transport Proteins; Methylation; Prognosis | 2022 |
Effects of the Methylation Levels for the Breast Cancer Associated Genes
Topics: BRCA1 Protein; Breast Neoplasms; Cell Proliferation; DNA Methylation; Female; gamma-Synuclein; Humans; Methylation; Neoplasm Proteins; RNA, Messenger; RNA, Small Interfering | 2022 |
PRC2-Mediated Epigenetic Suppression of Type I IFN-STAT2 Signaling Impairs Antitumor Immunity in Luminal Breast Cancer.
Topics: Breast Neoplasms; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Histones; Humans; Methylation; Polycomb Repressive Complex 2; STAT2 Transcription Factor; Tumor Microenvironment | 2022 |
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Female; Humans; Methylation; RNA Splicing Factors; RNA, Messenger; RNA, Small Interfering | 2023 |
Genistein induces endocrine resistance in human breast cancer by suppressing H3K27 trimethylation.
Topics: Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estrogens; Female; Genistein; Histones; Humans; Interleukin-6; Interleukin-8; Methylation; Receptor, ErbB-2; Tamoxifen | 2023 |
Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; BRCA1 Protein; Breast Neoplasms; Breast Neoplasms, Male; East Asian People; Humans; Male; Mastectomy; Methylation; Middle Aged; Mutation; Retrospective Studies | 2023 |
The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer.
Topics: Breast Neoplasms; Carcinogenesis; Cell Transformation, Neoplastic; Female; Humans; Methylation; Methyltransferases; Protein Serine-Threonine Kinases; RNA, Messenger; Transcription Factors | 2023 |
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression.
Topics: Breast Neoplasms; Female; Gene Expression; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Nuclear Proteins; Protein Isoforms; Repressor Proteins | 2023 |
Identification of novel class inhibitors of NSD3 methyltransferase showing a unique, bivalent binding mode in the SET domain.
Topics: Breast Neoplasms; Female; Histones; Humans; Methylation; PR-SET Domains; Protein Domains | 2023 |
MicroRNA-155-5p, Reduced by Curcumin-Re-Expressed Hypermethylated
Topics: Biomarkers; BRCA1 Protein; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Curcumin; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methylation; MicroRNAs | 2023 |
HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Humans; Lapatinib; Methylation; Peroxisomal Multifunctional Protein-2; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2 | 2023 |
Combined low levels of H4K16ac and H4K20me3 predicts poor prognosis in breast cancer.
Topics: Breast Neoplasms; Female; Histones; Humans; Lysine; Methylation; Prognosis | 2023 |
PRMT6 methylation of STAT3 regulates tumor metastasis in breast cancer.
Topics: Arginine; Breast Neoplasms; Female; Humans; Methylation; Nuclear Proteins; Protein-Arginine N-Methyltransferases; STAT3 Transcription Factor | 2023 |
Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer.
Topics: Breast Neoplasms; Female; Humans; Methylation; RNA; Tumor Microenvironment | 2023 |
Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.
Topics: Alternative Splicing; Breast Neoplasms; Cell Transformation, Neoplastic; Exons; Female; Humans; Methylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA; Serine-Arginine Splicing Factors | 2023 |
Primary tumor resection for initially staged IV breast cancer: An emphasis on programmed death-ligand 1 expression, promoter methylation status, and survival.
Topics: B7-H1 Antigen; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Programmed Cell Death 1 Receptor; Real-Time Polymerase Chain Reaction; Retrospective Studies; Turkey | 2019 |
Reduction of Global H3K27me
Topics: Adult; Animals; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Interferon Type I; Lysine; Methylation; Mice; Models, Biological; Molecular Targeted Therapy; Polycomb Repressive Complex 2; Receptor, ErbB-2; Retroelements; Trastuzumab; Up-Regulation | 2019 |
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Topics: Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Databases, Genetic; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational | 2019 |
Arginine methylation-dependent LSD1 stability promotes invasion and metastasis of breast cancer.
Topics: Arginine; Breast Neoplasms; Cell Line, Tumor; Histone Demethylases; Humans; Methylation; Protein Processing, Post-Translational; Ubiquitin-Specific Peptidase 7 | 2020 |
Bioinformatics Analysis of Metabolomics Data Unveils Association of Metabolic Signatures with Methylation in Breast Cancer.
Topics: Breast Neoplasms; Computational Biology; Female; Humans; Metabolome; Metabolomics; Methylation | 2020 |
Histone methyltransferases regulate the transcriptional expression of ERα and the proliferation of tamoxifen-resistant breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Methyltransferases; Humans; Methylation; RNA, Small Interfering; Tamoxifen | 2020 |
Crystal structure of human cytoplasmic tRNAHis-specific 5'-monomethylphosphate capping enzyme.
Topics: Antineoplastic Agents; Breast Neoplasms; Crystallography, X-Ray; Cytoplasm; Female; Gene Expression Regulation, Enzymologic; Humans; Methylation; Methyltransferases; Protein Conformation, alpha-Helical; Protein Folding; RNA, Transfer; RNA, Transfer, His; S-Adenosylhomocysteine | 2020 |
PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation.
Topics: Amino Acid Sequence; Arginine; Aurora Kinase B; Breast Neoplasms; Centromere; Chromosomal Proteins, Non-Histone; Chromosome Segregation; Chromosomes, Human; Cytokinesis; Demethylation; Disease Progression; Female; HeLa Cells; Histones; Humans; MCF-7 Cells; Methylation; Mitosis; Nuclear Proteins; Phosphorylation; Protein-Arginine N-Methyltransferases; RNA, Small Interfering | 2020 |
Digital imaging-assisted quantification of H3K27me3 immunoexpression in luminal A/B-like, HER2-negative, invasive breast cancer predicts patient survival and risk of recurrence.
Topics: Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Down-Regulation; Female; Histones; Humans; Image Interpretation, Computer-Assisted; Kaplan-Meier Estimate; Methylation; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Precision Medicine; Prognosis; Software | 2020 |
PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis.
Topics: Breast Neoplasms; Carcinogenesis; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Female; Humans; Methylation; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Polycomb Repressive Complex 2 | 2020 |
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.
Topics: Animals; Arginine; Breast Neoplasms; Citrullination; Citrulline; Female; Glycosylation; Histones; Humans; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Nucleosomes; Protein-Arginine Deiminase Type 4; Pyruvaldehyde | 2020 |
Silence of lncRNA MIAT-mediated inhibition of DLG3 promoter methylation suppresses breast cancer progression via the Hippo signaling pathway.
Topics: Animals; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Mice; Mice, Nude; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; Signal Transduction; Transcription Factors | 2020 |
MLL3 Induced by Luteolin Causes Apoptosis in Tamoxifen-Resistant Breast Cancer Cells through H3K4 Monomethylation and Suppression of the PI3K/AKT/mTOR Pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Luteolin; Methylation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; ras Proteins; Signal Transduction; Tamoxifen; TOR Serine-Threonine Kinases | 2020 |
Estrogen Induces Selective Transcription of Caveolin1 Variants in Human Breast Cancer through Estrogen Responsive Element-Dependent Mechanisms.
Topics: Adult; Aged; Breast Neoplasms; Caveolin 1; Cell Line, Tumor; Estradiol; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Middle Aged; Receptors, Estrogen; Response Elements | 2020 |
Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling.
Topics: Animals; Arginine; Breast; Breast Neoplasms; Cell Line, Tumor; Endosomes; Female; Focal Adhesion Kinase 1; Humans; Methylation; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Protein-Arginine N-Methyltransferases | 2020 |
Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Topics: Animals; Breast Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Phosphorylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; Ubiquitination | 2020 |
Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m
Topics: Adenosine; Adenylate Kinase; Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; MCF-7 Cells; Methylation; Methyltransferases; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Tamoxifen; Transfection | 2020 |
Macrophages-stimulated PRMT1-mediated EZH2 methylation promotes breast cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Interleukin-6; Intracellular Signaling Peptides and Proteins; Macrophages; Methylation; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Protein Stability; Protein-Arginine N-Methyltransferases; Repressor Proteins; Tumor Microenvironment; Ubiquitination; Xenograft Model Antitumor Assays | 2020 |
Pharmacologic downregulation of protein arginine methyltransferase1 expression by adenosine dialdehyde increases cell senescence in breast cancer.
Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Arginine; Betaine-Homocysteine S-Methyltransferase; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Molecular Docking Simulation; Oxidative Stress; Phosphatidylethanolamine N-Methyltransferase; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Repressor Proteins; Signal Transduction; Tamoxifen | 2021 |
Broad genic repression domains signify enhanced silencing of oncogenes.
Topics: Breast Neoplasms; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatin; Conserved Sequence; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lysine; Methylation; Nucleotide Motifs; Oncogenes; Regulatory Sequences, Nucleic Acid; RNA, Long Noncoding; Transcription Elongation, Genetic; Transcription Initiation, Genetic | 2020 |
Topics: Animals; Ankyrins; Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Dogs; Female; Humans; Mammary Neoplasms, Animal; Methylation; Neoplasm Proteins | 2020 |
Ribosome 18S m
Topics: Adenosine; Animals; Breast Neoplasms; Caenorhabditis elegans; Cell Growth Processes; Cell Line, Tumor; Female; HEK293 Cells; HeLa Cells; Humans; MCF-7 Cells; Methylation; Methyltransferases; RNA, Ribosomal, 18S | 2020 |
Impact of miRNAs expression modulation on the methylation status of breast cancer stem cell-related genes.
Topics: Breast Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplastic Stem Cells; Tumor Cells, Cultured | 2021 |
Topics: Breast Neoplasms; DNA Methylation; Drug Resistance, Neoplasm; Female; Humans; Methylation; Neoplasm Recurrence, Local; Nuclear Receptor Coactivator 3; PAX2 Transcription Factor; Promoter Regions, Genetic; Tamoxifen | 2022 |
A Risk Score System Based on the Methylation Levels of 15 RNAs in Breast Cancer.
Topics: Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Risk Factors; RNA-Binding Proteins; RNA, Long Noncoding; RNA, Messenger | 2022 |
mTORC1 stimulates cell growth through SAM synthesis and m
Topics: Adenosine; Animals; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Proliferation; Female; HEK293 Cells; HeLa Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Methionine Adenosyltransferase; Methylation; Mice, Nude; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; RNA Splicing Factors; RNA, Messenger; S-Adenosylmethionine; Signal Transduction; Transcription, Genetic | 2021 |
Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.
Topics: Alternative Splicing; Amino Acid Sequence; Arginine; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Heterogeneous Nuclear Ribonucleoprotein A1; Humans; Male; Methylation; Prostatic Neoplasms; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA, Small Interfering; Spliceosomes; Substrate Specificity | 2021 |
Differential methylation and expression patterns of microRNAs in relation to breast cancer subtypes among American women of African and European ancestry.
Topics: Black or African American; Breast Neoplasms; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Methylation; MicroRNAs; Middle Aged; United States; White People | 2021 |
Methyl-Donors Can Induce Apoptosis and Attenuate Both the Akt and the Erk1/2 Mediated Proliferation Pathways in Breast and Lung Cancer Cell Lines.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choline; Folic Acid; Humans; Lung; Lung Neoplasms; MAP Kinase Signaling System; Methionine; Methylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Vitamin B 12 | 2021 |
An insight into the promoter methylation of PHF20L1 and the gene association with metastasis in breast cancer.
Topics: Breast Neoplasms; Chromosomal Proteins, Non-Histone; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplasm Recurrence, Local; Promoter Regions, Genetic | 2021 |
Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.
Topics: Arginine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Lysine; Methylation; Mitochondria; Neoplasm Metastasis; Organoids; Oxidative Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2021 |
Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Female; Histone Code; Humans; Lamin Type B; Methylation; Middle Aged; Neoadjuvant Therapy | 2021 |
Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Heterografts; Humans; Kruppel-Like Transcription Factors; Methylation; Mice; Mice, Nude; Phosphorylation; Protein-Arginine N-Methyltransferases; Transfection | 2021 |
Thyroglobulin as a negative marker for malignancy in canine and human breast tumors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Dog Diseases; Dogs; Doxorubicin; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Methylation; NF-E2-Related Factor 2; Promoter Regions, Genetic; Survival Rate; Thyroglobulin | 2021 |
Dietary Methyl-Group Donor Intake and Breast Cancer Risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
Topics: Adult; Aged; Betaine; Breast Neoplasms; Choline; Diet; Europe; Female; Folic Acid; Humans; Methionine; Methylation; Middle Aged; Nutrition Assessment; Prospective Studies; Risk Factors | 2021 |
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
Topics: Animals; Antineoplastic Agents; Arginine; Biocatalysis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Enzyme Activation; Female; HEK293 Cells; Humans; Methylation; Mice, Nude; Mutation; Protein Binding; Protein Kinase Inhibitors; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Small Interfering; Signal Transduction | 2021 |
Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer.
Topics: Amino Acid Transport System y+; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Ferroptosis; Gene Expression Regulation, Neoplastic; Humans; Lipid Peroxidation; MCF-7 Cells; Metformin; Methylation; Mice; Proteins; Treatment Outcome; Xenograft Model Antitumor Assays | 2021 |
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1.
Topics: Adenosine; Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Male; Metabolome; Methylation; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neutrophils; Phosphopyruvate Hydratase; Phosphorylation; Principal Component Analysis; Promoter Regions, Genetic; Protein Stability; Receptor, Anaphylatoxin C5a; RNA Splicing Factors; Signal Transduction; Stochastic Processes; Survival Analysis; Tumor Suppressor Proteins; Up-Regulation | 2021 |
Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition.
Topics: Amino Acid Motifs; Antineoplastic Agents; Arginine; Breast Neoplasms; Chromatography, High Pressure Liquid; Computational Biology; Enzyme Inhibitors; Female; Gene Knockout Techniques; HEK293 Cells; Humans; MCF-7 Cells; Methylation; Molecular Targeted Therapy; Mutation; Proline; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Substrate Specificity; Tandem Mass Spectrometry | 2017 |
CRY2 is suppressed by FOXM1 mediated promoter hypermethylation in breast cancer.
Topics: Breast Neoplasms; Cryptochromes; Female; Forkhead Box Protein M1; Gene Expression Profiling; Humans; Methylation; Promoter Regions, Genetic; Tumor Cells, Cultured | 2017 |
A spin column-free approach to sodium hydroxide-based glycan permethylation.
Topics: Breast Neoplasms; Female; Humans; Methylation; Polysaccharides; Reproducibility of Results; Sodium Hydroxide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2017 |
The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer.
Topics: Acetylation; Breast Neoplasms; Epigenesis, Genetic; Female; Gene Regulatory Networks; Histones; Humans; Methylation; Promoter Regions, Genetic; Protein Processing, Post-Translational | 2017 |
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.
Topics: Animals; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Cell Line; Cell Line, Tumor; DNA Replication; DNA-Binding Proteins; Drug Resistance, Neoplasm; Endonucleases; Enhancer of Zeste Homolog 2 Protein; Female; Genomic Instability; HEK293 Cells; HeLa Cells; Histones; Humans; Methylation; Mice; Mice, Nude; Poly(ADP-ribose) Polymerase Inhibitors | 2017 |
Transcriptomic and epigenetic analysis of breast cancer stem cells.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplastic Stem Cells; Transcriptome | 2018 |
Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Posttranslational Modifications and Proteoforms.
Topics: Acetylation; Breast Neoplasms; Cell Cycle; Chromatin; Epigenesis, Genetic; Female; Histones; Humans; Methylation; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Proteome; Tumor Cells, Cultured | 2018 |
Methylation of NBPF1 as a novel marker for the detection of plasma cell-free DNA of breast cancer patients.
Topics: Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; DNA, Neoplasm; Female; Humans; Methylation | 2018 |
PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cadherins; Carcinogenesis; Carcinoma; Cell Line; Cell Proliferation; Cullin Proteins; DNA-Binding Proteins; F-Box-WD Repeat-Containing Protein 7; Female; HEK293 Cells; Histones; Humans; Methylation; Mice; Neoplasm Metastasis; Polycomb-Group Proteins; Protein-Arginine N-Methyltransferases; Transcription Factors; Transcription, Genetic | 2018 |
Regulation of Breast Cancer-Induced Osteoclastogenesis by MacroH2A1.2 Involving EZH2-Mediated H3K27me3.
Topics: Animals; Bone Resorption; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice, Inbred C57BL; Nucleosomes; Osteoclasts; Osteogenesis; Phosphorylation; Protein Binding; Protein-Lysine 6-Oxidase; Proto-Oncogene Proteins pp60(c-src) | 2018 |
Enhancing the Cancer Cell Growth Inhibitory Effects of Table Grape Anthocyanins.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caco-2 Cells; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Female; Fruit; Glucosides; HT29 Cells; Humans; Methylation; Nitriles; Oxidative Stress; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles; Vitis | 2018 |
Genome-Wide Methylation Analysis Identifies NOX4 and KDM5A as Key Regulators in Inhibiting Breast Cancer Cell Proliferation by Ginsenoside Rg3.
Topics: Breast Neoplasms; Cell Proliferation; Epigenesis, Genetic; Genome-Wide Association Study; Ginsenosides; Humans; MCF-7 Cells; Methylation; NADPH Oxidase 4; Prognosis; Retinoblastoma-Binding Protein 2 | 2018 |
Restoration of GATA4 expression impedes breast cancer progression by transcriptional repression of ReLA and inhibition of NF-κB signaling.
Topics: Antigens, CD; Apoptosis; Breast Neoplasms; Cadherins; Caspase 8; Cell Cycle; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Female; GATA4 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; MCF-7 Cells; Methylation; Neoplasm Invasiveness; NF-kappa B p50 Subunit; Phosphorylation; Promoter Regions, Genetic; Transcription Factor RelA; Transfection | 2019 |
Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration.
Topics: Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Histone-Lysine N-Methyltransferase; Humans; Intracellular Signaling Peptides and Proteins; Lysine; MCF-7 Cells; Methylation; Myeloid-Lymphoid Leukemia Protein; Protein Methyltransferases | 2018 |
Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cellular Senescence; DNA Damage; Extracellular Vesicles; Female; Fibroblasts; Genetic Loci; Humans; Inflammation; Interferon-beta; Interleukin-6; Longevity; Male; Methylation; MicroRNAs; Middle Aged; Plaque, Atherosclerotic; Ribonuclease H; Telomere Homeostasis; Young Adult | 2019 |
The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Estrogens; Female; Genes, src; Humans; Insulin-Like Growth Factor I; MCF-7 Cells; Methylation; Phosphatidylinositol 3-Kinases; Protein Binding; Protein-Arginine N-Methyltransferases; Receptor, IGF Type 1; Repressor Proteins; Signal Transduction | 2019 |
miR-29a contributes to breast cancer cells epithelial-mesenchymal transition, migration, and invasion via down-regulating histone H4K20 trimethylation through directly targeting SUV420H2.
Topics: Animals; Breast Neoplasms; Cell Movement; Cell Proliferation; Connective Tissue Growth Factor; Early Growth Response Protein 1; Epithelial-Mesenchymal Transition; Female; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; RNA Interference; Transplantation, Heterologous; Up-Regulation | 2019 |
Your DNA May Appear Older Than You Think.
Topics: Aging; Breast; Breast Neoplasms; DNA; Humans; Methylation | 2019 |
Changes of N6-methyladenosine modulators promote breast cancer progression.
Topics: Adenosine; Adult; Breast; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Datasets as Topic; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Methylation; Methyltransferases; Middle Aged; Mutation; Oxidoreductases, N-Demethylating; Prognosis; RNA, Messenger | 2019 |
Methylation of C/EBPα by PRMT1 Inhibits Its Tumor-Suppressive Function in Breast Cancer.
Topics: Animals; Arginine; Breast Neoplasms; CCAAT-Enhancer-Binding Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylases; Humans; Methylation; Mice, Inbred BALB C; Protein-Arginine N-Methyltransferases; Repressor Proteins; Xenograft Model Antitumor Assays | 2019 |
8-plex LC-MS/MS Analysis of Permethylated
Topics: Brain Neoplasms; Breast Neoplasms; Carbon Isotopes; Cell Line, Tumor; Chromatography, Liquid; Female; Glycomics; Glycoproteins; Humans; Hydrocarbons, Iodinated; Methylation; Polysaccharides; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2019 |
The overexpression of hypomethylated miR-663 induces chemotherapy resistance in human breast cancer cells by targeting heparin sulfate proteoglycan 2 (HSPG2).
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cyclophosphamide; Decitabine; DNA Methylation; DNA, Neoplasm; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Heparan Sulfate Proteoglycans; Humans; Methylation; MicroRNAs; Neoplasm Proteins; RNA, Neoplasm; Taxoids | 2013 |
PELP1 oncogenic functions involve CARM1 regulation.
Topics: Animals; Arginine; Breast Neoplasms; Chromatin Immunoprecipitation; Co-Repressor Proteins; Enzyme Inhibitors; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; MCF-7 Cells; Methylation; Mice; Promoter Regions, Genetic; Protein Interaction Mapping; Protein-Arginine N-Methyltransferases; Proto-Oncogene Mas; Proto-Oncogene Proteins; RNA, Small Interfering; Transcription Factors; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2013 |
Retinoic acid impairs estrogen signaling in breast cancer cells by interfering with activation of LSD1 via PKA.
Topics: Breast Neoplasms; Catalytic Domain; Chromatin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrogens; Female; Flavonoids; Histone Demethylases; Histones; Humans; Isoquinolines; MAP Kinase Signaling System; MCF-7 Cells; Methylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transcription, Genetic; Tretinoin | 2013 |
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.
Topics: Aged; Aged, 80 and over; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Epigenesis, Genetic; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lymph Nodes; Lymphatic Metastasis; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Repressor Proteins; Up-Regulation | 2013 |
microRNA-7 suppresses the invasive potential of breast cancer cells and sensitizes cells to DNA damages by targeting histone methyltransferase SET8.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Epithelial-Mesenchymal Transition; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; Neoplasm Proteins; RNA, Neoplasm | 2013 |
Towards sustained silencing of HER2/neu in cancer by epigenetic editing.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; HEK293 Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; MCF-7 Cells; Methylation; Ovarian Neoplasms; Promoter Regions, Genetic; Receptor, ErbB-2; Transcription Factors | 2013 |
Expression of polycomb targets predicts breast cancer prognosis.
Topics: Breast Neoplasms; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Immunoblotting; Kaplan-Meier Estimate; MCF-7 Cells; Methylation; Models, Genetic; Polycomb Repressive Complex 2; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2013 |
Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer.
Topics: Adult; Aged; Animals; Breast Neoplasms; Carcinogenesis; Carcinoma; Female; HEK293 Cells; Histones; Humans; MCF-7 Cells; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Middle Aged; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Protein Processing, Post-Translational; Repressor Proteins | 2013 |
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromosomal Proteins, Non-Histone; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasms; Peptide Chain Initiation, Translational; Prognosis; Protein Binding; Protein Biosynthesis; RNA, Ribosomal; Tumor Suppressor Protein p53 | 2013 |
UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Kaplan-Meier Estimate; Methylation; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Nuclear Proteins; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational | 2014 |
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Chromatin; Co-Repressor Proteins; Crystallography, X-Ray; Disease-Free Survival; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Oncogenes; Prognosis; Protein Binding; Protein Conformation; Protein Structure, Tertiary; RNA Polymerase II; Substrate Specificity; Transcription Elongation, Genetic | 2014 |
LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer.
Topics: Adult; Aged; Aged, 80 and over; AMP-Activated Protein Kinase Kinases; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Female; Humans; Methylation; Middle Aged; Phosphatidylinositol 3-Kinases; Prognosis; Protein Serine-Threonine Kinases; src-Family Kinases; Transfection | 2014 |
Induction of the mesenchymal to epithelial transition by demethylation- activated microRNA-200c is involved in the anti-migration/invasion effects of arsenic trioxide on human breast cancer cells.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; MicroRNAs; Neoplasm Invasiveness; Oxides; Up-Regulation | 2015 |
Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor α via distinct mechanisms.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding, Competitive; Breast Neoplasms; Cell Nucleus; Cell Proliferation; Estrogen Receptor alpha; Female; Gene Silencing; HSP90 Heat-Shock Proteins; Humans; Ligands; MCF-7 Cells; Methylation; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Protein-Arginine N-Methyltransferases; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Progesterone; src-Family Kinases; Up-Regulation | 2014 |
Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Silencing; Histone Demethylases; Histones; Humans; Inhibitory Concentration 50; Methylation; RNA, Small Interfering; Transcriptional Activation; Tumor Stem Cell Assay | 2014 |
Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease-Free Survival; Female; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Methylation; Neoplasm Grading; Neoplasm Invasiveness; Receptor, ErbB-2; RNA Interference; RNA, Small Interfering | 2014 |
Arsenic methylation capacity is associated with breast cancer in northern Mexico.
Topics: Arsenic; Breast Neoplasms; Case-Control Studies; Drinking Water; Female; Humans; Methylation; Mexico; Middle Aged; Water Pollutants, Chemical | 2014 |
Remodeling of the methylation landscape in breast cancer metastasis.
Topics: Breast Neoplasms; CpG Islands; Female; Humans; Methylation; Promoter Regions, Genetic | 2014 |
Metastasis-associated protein ribosomal RNA processing 1 homolog B (RRP1B) modulates metastasis through regulation of histone methylation.
Topics: Animals; Apoptosis Regulatory Proteins; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Lung Neoplasms; Methylation; Mice; Neoplasms, Experimental; Repressor Proteins; Transcription, Genetic; Tripartite Motif-Containing Protein 28 | 2014 |
A methylation-based regulatory network for microRNA 320a in chemoresistant breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Regulatory Networks; Humans; MCF-7 Cells; Methylation; MicroRNAs; NFATC Transcription Factors; Promoter Regions, Genetic; Proto-Oncogene Protein c-ets-1; TRPC Cation Channels | 2014 |
Association of H3K9me3 and H3K27me3 repressive histone marks with breast cancer subtypes in the Nurses' Health Study.
Topics: Adult; Breast Neoplasms; Epidemiologic Studies; Estrogen Receptor alpha; Female; Histones; Humans; Life Style; Lysine; Methylation; Middle Aged; Multivariate Analysis; Receptor, ErbB-2; Receptors, Progesterone; Reproductive History; Risk Factors; United States | 2014 |
BCCTBbp: the Breast Cancer Campaign Tissue Bank bioinformatics portal.
Topics: Breast Neoplasms; Computational Biology; Databases, Genetic; Female; Gene Expression Profiling; Genomics; Humans; Internet; Methylation; MicroRNAs; Proteomics; Tissue Banks | 2015 |
Histone Methyltransferase hSETD1A Is a Novel Regulator of Metastasis in Breast Cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epigenesis, Genetic; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Matrix Metalloproteinases; MCF-7 Cells; Methylation; Mice; Neoplasm Metastasis; Up-Regulation | 2015 |
The differential localization of a methyl group confers a different anti-breast cancer activity to two triterpenes present in olives.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Female; Fruit; Humans; Methylation; Molecular Structure; Neoplasm Invasiveness; Olea; Oleanolic Acid; Oxidative Stress; Reactive Oxygen Species; Stereoisomerism; Triterpenes | 2015 |
DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Topics: Alternative Splicing; beta Catenin; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Methylation; Neoplasm Invasiveness; RNA, Messenger; Up-Regulation | 2015 |
NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT.
Topics: Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; Lysine; Membrane Proteins; Methylation; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Prognosis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Sesquiterpenes; Transcription Factor RelA; Urinary Bladder Neoplasms | 2015 |
Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.
Topics: Animals; Aurora Kinase A; Breast Neoplasms; Calcium-Binding Proteins; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p27; Female; Histones; Humans; Intercellular Signaling Peptides and Proteins; Mammary Neoplasms, Animal; Methylation; Mice; Mice, Transgenic; Protein Tyrosine Phosphatase, Non-Receptor Type 11; S-Phase Kinase-Associated Proteins; Tumor Suppressor Protein p53 | 2015 |
Cell signaling events differentiate ER-negative subtypes from ER-positive breast cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Methylation; Receptor, ErbB-2; Signal Transduction | 2015 |
Quantitative detection of methylation of FHIT and BRCA1 promoters in the serum of ductal breast cancer patients.
Topics: Acid Anhydride Hydrolases; BRCA1 Protein; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; DNA Methylation; Early Detection of Cancer; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasm Proteins; Promoter Regions, Genetic | 2015 |
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
Topics: Amino Acid Motifs; Arginine; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; DNA Damage; Female; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Methylation; Protein-Arginine N-Methyltransferases; Ubiquitination | 2015 |
Kaiso represses the expression of glucocorticoid receptor via a methylation-dependent mechanism and attenuates the anti-apoptotic activity of glucocorticoids in breast cancer cells.
Topics: Apoptosis; Base Sequence; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Female; Gene Expression Regulation, Neoplastic; Glucocorticoids; Humans; Methylation; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Signal Transduction; Transcription Factors | 2016 |
DOT1L: a new therapeutic target for aggressive breast cancer.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Epithelial-Mesenchymal Transition; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia; Methylation; Methyltransferases; Mice; Neoplastic Stem Cells; Transcriptional Activation | 2015 |
Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Female; HSP70 Heat-Shock Proteins; Humans; Kaplan-Meier Estimate; Lysine; Methylation; Middle Aged; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Prognosis; Proportional Hazards Models; Protein Processing, Post-Translational | 2015 |
Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples.
Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Female; Histones; Humans; Leukemia, Promyelocytic, Acute; Methylation; Mice; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; Tissue Fixation | 2016 |
Quantitative Profiling of Post-translational Modifications by Immunoaffinity Enrichment and LC-MS/MS in Cancer Serum without Immunodepletion.
Topics: Acetylation; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatography, Liquid; Female; Humans; Leukemia, Myeloid, Acute; Methylation; Neoplasm Proteins; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry | 2016 |
ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Proliferation; DNA-Binding Proteins; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histone Demethylases; Histones; Humans; Lysine; MCF-7 Cells; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Prognosis; Protein Binding; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2016 |
DOT1L histone methyltransferase regulates the expression of BCAT1 and is involved in sphere formation and cell migration of breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Methylation; Methyltransferases; Neoplasm Metastasis; Transaminases | 2016 |
Selective inhibition of EZH2 by ZLD1039 blocks H3K27 methylation and leads to potent anti-tumor activity in breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Enhancer of Zeste Homolog 2 Protein; Female; Histones; Humans; Intracellular Space; Methylation; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Polycomb Repressive Complex 2; Pyridones; Quinolones; Small Molecule Libraries; Transcriptional Activation; Xenograft Model Antitumor Assays | 2016 |
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.
Topics: AlkB Homolog 5, RNA Demethylase; Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Catalysis; Cell Hypoxia; Cell Line, Tumor; Female; Gene Knockdown Techniques; Humans; Methylation; Nanog Homeobox Protein; Neoplastic Stem Cells; RNA, Messenger | 2016 |
Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; MCF-7 Cells; Methylation; Mice; Mice, Nude | 2016 |
Targeting the epigenetics of the DNA damage response in breast cancer.
Topics: Animals; Apoptosis; BRCA1 Protein; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Chromatin; Dipyridamole; DNA Breaks, Double-Stranded; DNA Repair; Epigenesis, Genetic; Female; Folic Acid Antagonists; Histones; Humans; MCF-7 Cells; Methylation; Mice; Mice, Inbred BALB C; Protein-Arginine N-Methyltransferases; Repressor Proteins; Tumor Suppressor p53-Binding Protein 1 | 2016 |
Lysine demethylase KDM3A regulates breast cancer cell invasion and apoptosis by targeting histone and the non-histone protein p53.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Mutation; Neoplastic Stem Cells; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2017 |
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Neoplasm Invasiveness; Neoplasms; Prognosis; Protein-Arginine N-Methyltransferases; Sequence Analysis, RNA; Transcription, Genetic; Transforming Growth Factor beta | 2017 |
PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Cycle; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Lysine; Methylation; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Transport; Proto-Oncogene Proteins c-akt; Retinoblastoma-Binding Protein 2; Subcellular Fractions; Substrate Specificity; Treatment Outcome | 2016 |
H3K4 acetylation, H3K9 acetylation and H3K27 methylation in breast tumor molecular subtypes.
Topics: Acetylation; Breast Neoplasms; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Receptors, Cytoplasmic and Nuclear | 2016 |
Large intergenic non-coding RNA-ROR reverses gemcitabine-induced autophagy and apoptosis in breast cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Deoxycytidine; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Methylation; MicroRNAs; Promoter Regions, Genetic; RNA, Long Noncoding | 2016 |
MiR-375 is epigenetically downregulated due to promoter methylation and modulates multi-drug resistance in breast cancer cells via targeting YBX1.
Topics: Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Methylation; MicroRNAs; Y-Box-Binding Protein 1 | 2016 |
Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women.
Topics: Adult; Aged; Arsenic; Arsenicals; Breast Neoplasms; Carrier Proteins; Case-Control Studies; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Genetic Predisposition to Disease; Humans; Mass Spectrometry; Methylation; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; PPAR gamma; Risk; RNA-Binding Proteins; Young Adult | 2016 |
SMYD3-Mediated H2A.Z.1 Methylation Promotes Cell Cycle and Cancer Proliferation.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin A1; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice | 2016 |
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.
Topics: Adenosine; AlkB Homolog 5, RNA Demethylase; Animals; Breast Neoplasms; Cell Hypoxia; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; MCF-7 Cells; Methylation; Mice; Mice, SCID; Nanog Homeobox Protein; Neoplastic Stem Cells; RNA, Messenger; RNA, Small Interfering; Trans-Activators; Xenograft Model Antitumor Assays | 2016 |
Epigenetic regulation of long noncoding RNA UCA1 by SATB1 in breast cancer.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Epigenesis, Genetic; Female; Flow Cytometry; Genes, Reporter; Histones; Humans; Matrix Attachment Region Binding Proteins; Methylation; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Long Noncoding; RNA, Messenger; RNA, Small Interfering; Sequence Analysis, RNA; Up-Regulation | 2016 |
Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4.
Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycomics; Humans; Methylation; MicroRNAs; Middle Aged; N-Acetylneuraminic Acid; Neoplasm Metastasis; Polysaccharides; Sialyltransferases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells.
Topics: Acetylation; Breast Neoplasms; E1A-Associated p300 Protein; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glucuronosyltransferase; Histone Deacetylase Inhibitors; Humans; Hyaluronan Receptors; Hyaluronan Synthases; Hyaluronic Acid; Hydroxamic Acids; MCF-7 Cells; Methylation; Phosphorylation; Phosphoserine; Protein Binding; Subcellular Fractions | 2017 |
Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer.
Topics: beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; DNA Helicases; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Essential; Glycogen Synthase Kinase 3 beta; Histones; Humans; Lysine; Male; Methylation; Molecular Targeted Therapy; Neoplasms; NF-kappa B; Phosphorylation; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Stability; Proteolysis; PTEN Phosphohydrolase; Tumor Necrosis Factor-alpha; Ubiquitination | 2017 |
Automethylation of protein arginine methyltransferase 7 and its impact on breast cancer progression.
Topics: Animals; Breast Neoplasms; Female; Gene Deletion; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; Protein-Arginine N-Methyltransferases | 2017 |
Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enhancer Elements, Genetic; Estradiol; Estrogen Receptor alpha; Female; GATA3 Transcription Factor; Gene Expression Regulation, Neoplastic; Genomics; Hepatocyte Nuclear Factor 3-alpha; Histones; Humans; Lysine; Methylation; Oncogenes; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Transcription, Genetic | 2017 |
Regulation of estrogen rapid signaling through arginine methylation by PRMT1.
Topics: Animals; Arginine; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytoplasm; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Estrogens; Genome, Human; Humans; Methylation; Mice; Models, Biological; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Receptor Cross-Talk; Repressor Proteins; Signal Transduction; Substrate Specificity | 2008 |
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.
Topics: Acetylation; Antigens, CD; Apoptosis; Blotting, Western; Breast Neoplasms; Cadherins; CARD Signaling Adaptor Proteins; Cells, Cultured; Chromatin Immunoprecipitation; CpG Islands; Cytoskeletal Proteins; Epigenesis, Genetic; Estrogen Receptor alpha; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Histones; Humans; Kidney; Lysine; Methylation; Nucleosomes; Polymerase Chain Reaction; RNA, Small Interfering | 2008 |
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells.
Topics: Acetylation; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Female; Gene Silencing; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Methylation; NF-kappa B; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Superoxide Dismutase; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Probe signal correction for differential methylation hybridization experiments.
Topics: Base Sequence; Breast Neoplasms; Carbocyanines; Cell Line, Tumor; DNA Methylation; DNA Probes; Female; Fluorescent Dyes; Gene Expression Profiling; Humans; Methylation; Models, Genetic; Models, Statistical; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Sequence Analysis, DNA; Signal Transduction | 2008 |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Topics: 3' Untranslated Regions; Algorithms; Breast Neoplasms; Cell Line, Tumor; Disease Progression; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Lysine; Male; Methylation; MicroRNAs; Neoplasm Metastasis; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Small Interfering; Stomach Neoplasms; Transcription Factors | 2008 |
NMe amide as a synthetic surrogate for the thioester moiety in thiocoraline.
Topics: Amides; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Colon; Depsipeptides; Drug Stability; Esters; Humans; Hydrogen Bonding; Male; Methylation; Protein Conformation; Sulfides | 2009 |
Molecular mechanisms of drug resistance.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Colonic Neoplasms; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Fluorouracil; Gene Expression; Genes, p53; Humans; Methylation; Mitosis; Receptor, ErbB-2; Signal Transduction; Uracil-DNA Glycosidase | 2009 |
Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.
Topics: Acetylation; Biomarkers, Tumor; Breast Neoplasms; Cluster Analysis; Female; Histones; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Methylation; Microarray Analysis; Neoplasm Invasiveness; Phenotype; Prognosis | 2009 |
Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.
Topics: Acetylation; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Chromatin Assembly and Disassembly; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Female; Gene Silencing; Histones; Humans; Methylation; Nucleosomes | 2009 |
Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription.
Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Receptors, Estrogen; Sequence Alignment; Transcription, Genetic | 2009 |
Mapping of lysine monomethylation of linker histones in human breast and its cancer.
Topics: Aged; Breast; Breast Neoplasms; Female; Histones; Humans; Linear Models; Lysine; Methylation; Middle Aged; Peptide Fragments; Peptide Mapping; Proteomics; Tandem Mass Spectrometry | 2009 |
Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration.
Topics: Actins; Animals; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeleton; Enzyme Activation; Female; Guanine Nucleotide Dissociation Inhibitors; Humans; Indoles; Methylation; Protein Methyltransferases; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Signal Transduction | 2009 |
Troglitazone inhibits histone deacetylase activity in breast cancer cells.
Topics: Acetylation; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Butyrates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Dose-Response Relationship, Drug; Epigenesis, Genetic; Female; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Methylation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfonamides; Thiazolidinediones; Troglitazone | 2010 |
Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cytoplasm; Disease Progression; Gene Expression Regulation; GTP-Binding Proteins; Humans; Methylation; Microscopy, Electron; Microscopy, Fluorescence; Protein Biosynthesis; Ribosomes; RNA Processing, Post-Transcriptional; RNA, Ribosomal; RNA, Ribosomal, 28S; Tumor Suppressor Protein p53 | 2009 |
A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells.
Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Biocatalysis; Breast Neoplasms; Carcinogens; Catechol O-Methyltransferase; Cell Line, Tumor; Chemoprevention; Culture Media, Conditioned; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Inhibitors; Estradiol; Estrogens, Catechol; Female; Flavones; Flavonoids; Gene Expression; Glucuronidase; Humans; Hydroxylation; Kinetics; Methylation; Oxazines; Recombinant Proteins; Sulfatases | 2010 |
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Topics: Adenosine; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Methylation; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factors | 2009 |
UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.
Topics: Acetylation; Binding Sites; BRCA1 Protein; Breast Neoplasms; Carcinoma, Ductal, Breast; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; CREB-Binding Protein; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; E1A-Associated p300 Protein; Epigenesis, Genetic; Estradiol; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histocompatibility Antigens; Histone Deacetylase 1; Histone-Lysine N-Methyltransferase; Histones; Humans; Hydrogen Peroxide; Immunohistochemistry; Methylation; MyoD Protein; Oxidants; Oxidative Stress; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription, Genetic; Transfection; Ubiquitin-Protein Ligases | 2010 |
Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.
Topics: Anticarcinogenic Agents; Arachidonic Acid; Breast Neoplasms; Cadherins; Cell Line, Tumor; Dietary Fats; DNA-Binding Proteins; Docosahexaenoic Acids; Down-Regulation; Eicosapentaenoic Acid; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Proteins; Linoleic Acid; Methylation; Neoplasm Invasiveness; Neoplasm Proteins; Polycomb Repressive Complex 2; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Transcription Factors | 2010 |
Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology.
Topics: Adenocarcinoma; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin A2; Cyclin-Dependent Kinase Inhibitor p21; Enzyme-Linked Immunosorbent Assay; Female; Genes, erbB-2; Histone Demethylases; Histones; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Progesterone; RNA Interference; RNA, Small Interfering | 2010 |
Molecular mechanisms of green tea polyphenols.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Biological Availability; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Humans; Male; Methylation; Mice; Phenols; Polyphenols; Prodrugs; Proteasome Inhibitors; Rats; Tea; Ubiquitinated Proteins | 2009 |
Glycomic analysis of sialic acid linkages in glycans derived from blood serum glycoproteins.
Topics: Amides; Analysis of Variance; Blood Proteins; Breast Neoplasms; Female; Glycomics; Glycoproteins; Humans; Isomerism; Lactones; Methylation; N-Acetylneuraminic Acid; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Chromatin Assembly and Disassembly; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Genome, Human; Histones; Humans; Methylation; Mice; Mice, Nude; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Polycomb-Group Proteins; Prognosis; Repressor Proteins; RNA Interference; RNA, Untranslated; Survival Rate | 2010 |
Chip-based reversed-phase liquid chromatography-mass spectrometry of permethylated N-linked glycans: a potential methodology for cancer-biomarker discovery.
Topics: Ammonia; Biomarkers, Tumor; Boranes; Breast Neoplasms; Chromatography, Reverse-Phase; Female; Glycomics; Glycoproteins; Humans; Mass Spectrometry; Methylation; Polysaccharides; Reproducibility of Results | 2010 |
p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells.
Topics: Breast; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Epithelial Cells; Gene Silencing; Histones; Humans; Methylation; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telomerase | 2010 |
Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function.
Topics: Blotting, Western; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Immunoprecipitation; Methylation; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2010 |
SILAC-based proteomic analysis to dissect the "histone modification signature" of human breast cancer cells.
Topics: Acetylation; Amino Acid Sequence; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Female; Histones; Humans; Isotope Labeling; Methylation; Molecular Sequence Data; Peptide Fragments; Phenotype; Protein Processing, Post-Translational; Proteomics | 2011 |
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; CCCTC-Binding Factor; Cell Line; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Estrogen Receptor alpha; Feedback, Physiological; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Immunoblotting; Lysine; Methylation; MicroRNAs; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; ras Proteins; Repressor Proteins; RNA Interference | 2010 |
TRIM24 links a non-canonical histone signature to breast cancer.
Topics: Acetylation; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Chromatin; Chromatin Assembly and Disassembly; Crystallography, X-Ray; Estrogen Receptor alpha; Estrogens; Gene Expression Regulation, Neoplastic; HEK293 Cells; Histones; Humans; Methylation; Protein Array Analysis; Protein Binding; Protein Structure, Tertiary; Substrate Specificity; Survival Rate | 2010 |
Epigenetic reprogramming of breast cancer cells with oocyte extracts.
Topics: Ambystoma mexicanum; Animals; Breast Neoplasms; Cell Extracts; Cell Membrane Permeability; Cell Survival; Chromatin Assembly and Disassembly; Digitonin; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Profiling; Genes, Tumor Suppressor; Histones; Humans; Methylation; Mice; Microfilament Proteins; Neoplasm Transplantation; Oocytes; Promoter Regions, Genetic; Transcriptional Activation; Transplantation, Heterologous; Tumor Cells, Cultured; Xenopus | 2011 |
Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells.
Topics: Acetylation; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Computational Biology; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Demethylases; Histones; Humans; Methylation | 2012 |
FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells.
Topics: Acetylation; Animals; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Chromatin Immunoprecipitation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins; Repressor Proteins; RNA Interference; RNA, Small Interfering; Transcription Factors; Transfection | 2012 |
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lentivirus; Methylation; Multiprotein Complexes; Neoplasm Proteins; RNA Interference; Ultracentrifugation | 2011 |
Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; TCF Transcription Factors | 2011 |
A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer.
Topics: Bayes Theorem; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epigenesis, Genetic; Estrogen Receptor alpha; Gene Regulatory Networks; Genomics; Histones; Humans; Lysine; Methylation; Models, Genetic; Reproducibility of Results; RNA Polymerase II; Tamoxifen; Time Factors | 2011 |
Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Chemokines, CC; Chick Embryo; Chromatin Assembly and Disassembly; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Multiprotein Complexes; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; Nuclear Proteins; Protein Interaction Mapping; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Repressor Proteins; RNA, Small Interfering | 2011 |
Histone demethylation and steroid receptor function in cancer.
Topics: Animals; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Prostatic Neoplasms; Receptors, Steroid | 2012 |
Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e.
Topics: Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cyclin D1; Epigenesis, Genetic; Female; Gene Silencing; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; MicroRNAs; Nuclear Proteins; Repressor Proteins | 2011 |
Subtype-specific alterations of the Wnt signaling pathway in breast cancer: clinical and prognostic significance.
Topics: Adenomatous Polyposis Coli Protein; Adult; Aged; Antigens, CD; beta Catenin; Breast Neoplasms; Breast Neoplasms, Male; Cadherins; Female; Humans; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Methylation; Middle Aged; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Wnt Proteins; Wnt Signaling Pathway | 2012 |
An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression.
Topics: Acetylation; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Glutamine; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Repressor Proteins | 2012 |
FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.
Topics: Acetylation; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Female; Forkhead Transcription Factors; Gene Expression Regulation; HEK293 Cells; Histone Acetyltransferases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Mutation; Nuclear Proteins; Repressor Proteins | 2011 |
A gestational low-protein diet represses p21(WAF1/Cip1) expression in the mammary gland of offspring rats through promoter histone modifications.
Topics: Acetylation; Animals; Breast Neoplasms; Chromatin; Cyclin-Dependent Kinase Inhibitor p21; Diet, Protein-Restricted; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Female; Histones; Mammary Glands, Animal; Maternal Nutritional Physiological Phenomena; Methylation; Organ Specificity; Pregnancy; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Estrogen metabolism and risk of breast cancer in postmenopausal women.
Topics: Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Chromatography, Liquid; Confounding Factors, Epidemiologic; Estradiol; Estrogens; Estrogens, Catechol; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Methylation; Middle Aged; Multivariate Analysis; Neoplasms, Hormone-Dependent; Odds Ratio; Postmenopause; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Estrogen; Risk Assessment; Risk Factors; Tandem Mass Spectrometry | 2012 |
Functional elements demarcated by histone modifications in breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Promoter Regions, Genetic; Regulatory Elements, Transcriptional | 2012 |
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Animals; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histocompatibility Antigens; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Mice, Inbred ICR; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasm Transplantation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Snail Family Transcription Factors; Transcription Factors | 2012 |
Gene-specific patterns of coregulator requirements by estrogen receptor-α in breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Myeloid-Lymphoid Leukemia Protein; Promoter Regions, Genetic; Protein Processing, Post-Translational; Receptors, Progesterone; Response Elements; RNA Polymerase II; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Trefoil Factor-1; Tumor Suppressor Proteins | 2012 |
Dysregulated recruitment of the histone methyltransferase EZH2 to the class II transactivator (CIITA) promoter IV in breast cancer cells.
Topics: Acetylation; Base Sequence; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Histones; HLA-DR alpha-Chains; Humans; Interferon-gamma; Methylation; Molecular Sequence Data; Nuclear Proteins; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA, Small Interfering; Trans-Activators; Transcription Factors | 2012 |
Accumulation of cyclophilin A isoforms in conditioned medium of irradiated breast cancer cells.
Topics: Acetylation; Breast Neoplasms; Cell Death; Cell Line, Tumor; Culture Media, Conditioned; Cyclophilin A; Female; Humans; Methylation; Protein Isoforms; Protein Processing, Post-Translational; Proteomics; Radiation, Ionizing; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2012 |
MTA1 expression correlates significantly with ER-alpha methylation in breast cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Mammary Glands, Human; Methylation; Middle Aged; Neoplasm Staging; Repressor Proteins; Trans-Activators | 2012 |
Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.
Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Immunohistochemistry; Methylation; Mutation; Polycomb Repressive Complex 2 | 2012 |
Accumulation of unusual gangliosides G(Q3) and G(P3) in breast cancer cells expressing the G(D3) synthase.
Topics: Breast Neoplasms; Female; Gangliosides; Gene Expression; Glycosphingolipids; Humans; MCF-7 Cells; Methylation; Sialyltransferases | 2012 |
The regulatory mechanism of the LY6K gene expression in human breast cancer cells.
Topics: Antigens, Ly; Binding Sites; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Methylation; Neoplasm Invasiveness; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factor AP-1 | 2012 |
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression.
Topics: Amino Acid Sequence; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Histone Demethylases; Histones; Humans; Immunohistochemistry; MCF-7 Cells; Methylation; Molecular Sequence Data; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Snail Family Transcription Factors; Transcription Factors; Ubiquitination; Wnt Signaling Pathway | 2012 |
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation | 2013 |
Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancers.
Topics: Adult; Base Sequence; Breast Neoplasms; Carcinoma, Ductal, Breast; DNA Copy Number Variations; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Middle Aged; Mutation; Neoplasm Invasiveness; Nuclear Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2013 |
Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Proliferation; Female; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Membrane Proteins; Methylation; Mitochondrial Proteins; Monoamine Oxidase Inhibitors; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Pargyline; Protocadherins; RGS Proteins; RNA Interference; RNA, Small Interfering; Vorinostat | 2013 |
Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.
Topics: Acetylation; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cell Survival; CREB-Binding Protein; Curcumin; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flow Cytometry; Histone Acetyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunohistochemistry; Lysine Acetyltransferase 5; MCF-7 Cells; Methylation; Polymerase Chain Reaction; Protein Processing, Post-Translational; RNA Interference; Terpenes; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2013 |
E-cadherin promoter methylation can regulate its expression in invasive ductal breast cancer tissue in Chinese woman.
Topics: Actins; Adult; Aged; Blotting, Western; Breast Neoplasms; Cadherins; Carcinoma, Ductal, Breast; China; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Middle Aged; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
Medical hypothesis: hyperhomocysteinemia is a risk factor for estrogen-induced hormonal cancer.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Estradiol; Estrogens; Estrogens, Catechol; Female; Folic Acid; Humans; Hyperhomocysteinemia; Kinetics; Methylation; Models, Biological; Mutagenicity Tests; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Risk Factors; S-Adenosylhomocysteine; Uterine Neoplasms; Vitamin B 12; Vitamin B 6 | 2003 |
Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Chromatography, High Pressure Liquid; Estrogens; Female; Humans; Methylation; Middle Aged | 2003 |
Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.
Topics: Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Equilenin; Estradiol Congeners; Female; Humans; Methylation; Risk Factors; Temperature | 2004 |
Aberrant CBFA2T3B gene promoter methylation in breast tumors.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Methylation; Phosphoproteins; Promoter Regions, Genetic; Protein Subunits; Repressor Proteins; Sequence Analysis, DNA; Sulfites; Tumor Suppressor Proteins | 2004 |
DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cloning, Molecular; Humans; Lung Neoplasms; Membrane Proteins; Methylation; Microfilament Proteins; Protein-Arginine N-Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae; Tumor Suppressor Proteins | 2004 |
An EGF receptor inhibitor induces RAR-beta expression in breast and ovarian cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; ErbB Receptors; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Methylation; Ovarian Neoplasms; Promoter Regions, Genetic; Quinazolines; Receptor, ErbB-2; Receptors, Retinoic Acid; RNA, Messenger | 2005 |
Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; Immunohistochemistry; Methylation; Promoter Regions, Genetic; Recurrence; Repressor Proteins; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2005 |
The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 3; Caspase 8; Cell Line, Tumor; Enzyme Activation; Humans; Membrane Proteins; Methylation; Microfilament Proteins; Tumor Suppressor Proteins | 2006 |
Aberrant methylation of cyclooxygenase-2 in breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; CpG Islands; Cyclooxygenase 2; DNA, Neoplasm; Female; Gene Silencing; Humans; Immunohistochemistry; Methylation; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells.
Topics: Adenocarcinoma; Antigens, CD; Antigens, Neoplasm; Biomarkers, Tumor; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; CpG Islands; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Ki-67 Antigen; Leukemia; Lymphoma; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2006 |
Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer.
Topics: Allelic Imbalance; Breast Neoplasms; Female; Gene Deletion; Gene Silencing; Genes, BRCA1; Genes, p53; Germ-Line Mutation; Humans; Methylation; Phenotype | 2006 |
hCAF1, a new regulator of PRMT1-dependent arginine methylation.
Topics: Adaptor Proteins, Signal Transducing; Arginine; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Female; Gene Expression Regulation; HeLa Cells; Histones; Humans; Methylation; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; RNA-Binding Proteins; RNA, Small Interfering; Transcription Factors | 2007 |
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3.
Topics: Acetylation; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin D; Cyclins; Endodeoxyribonucleases; Female; Histone Acetyltransferases; Histones; Humans; Leptin; Methylation; Obesity; Postmenopause; Promoter Regions, Genetic; Protein Modification, Translational; S Phase; STAT3 Transcription Factor; Tyrphostins | 2007 |
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
Topics: Adenosine; Adenosylhomocysteinase; Apoptosis; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histones; Humans; Methylation; Polycomb-Group Proteins; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; RNA Polymerase II; RNA, Small Interfering | 2007 |
Mass spectrometric analysis of high-mobility group proteins and their post-translational modifications in normal and cancerous human breast tissues.
Topics: Amino Acid Sequence; Breast; Breast Neoplasms; Female; HMGA1a Protein; HMGA1b Protein; Humans; Lysine; Methylation; Molecular Sequence Data; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry | 2007 |
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.
Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Catechin; Cell Division; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; Lysine; Male; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Telomerase | 2008 |
Tissues tell the real tale of breast cancer.
Topics: Amino Acid Sequence; Breast Neoplasms; Female; HMGA1a Protein; HMGA1b Protein; Humans; Methylation; Molecular Sequence Data; Protein Processing, Post-Translational; Proteomics; Tumor Cells, Cultured | 2007 |
Comparative glycomic mapping through quantitative permethylation and stable-isotope labeling.
Topics: Breast Neoplasms; Female; Humans; Isotope Labeling; Methylation; Polysaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Histones; Humans; Mammary Neoplasms, Animal; Methylation; Mice; Phosphorylation; Regulatory Elements, Transcriptional; Signal Transduction | 2008 |
BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype.
Topics: Adult; Alleles; BRCA1 Protein; Breast Neoplasms; Disease Susceptibility; DNA; Female; Genetic Predisposition to Disease; Humans; Methylation; Middle Aged; Mutation; Phenotype; Promoter Regions, Genetic | 2008 |
Hypermethylation analysis of mismatch repair genes (hmlh1 and hmsh2) in locally advanced breast cancers in Indian women.
Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; CpG Islands; DNA Mismatch Repair; Female; Gene Expression Regulation, Neoplastic; Genomic Instability; Humans; Loss of Heterozygosity; Methylation; Microsatellite Instability; MutL Protein Homolog 1; MutS Homolog 2 Protein; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells.
Topics: Breast; Breast Neoplasms; Catechol O-Methyltransferase; Catechols; Cell Line, Tumor; Cytosol; Epithelial Cells; Estrogens; Female; Humans; Methylation; Recombinant Proteins; Sulfates; Sulfotransferases; Sulfur Radioisotopes; Tropolone | 2008 |
Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line; Crystallography, X-Ray; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Conformation; Protein Methyltransferases; Sequence Alignment | 2008 |
Breast cancer diagnosis and prognosis through quantitative measurements of serum glycan profiles.
Topics: Analysis of Variance; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Female; Glycomics; Glycoproteins; Glycosylation; Humans; Methylation; Neoplasm Staging; Oligosaccharides; Polysaccharides; Principal Component Analysis; Prognosis; ROC Curve; Serum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
Multivariate analysis of urinary RNA catabolites in malignancies: cross-sectional and longitudinal studies.
Topics: Analysis of Variance; Autoanalysis; Breast Neoplasms; Female; Humans; Kidney Neoplasms; Longitudinal Studies; Lung Neoplasms; Lymphoma; Male; Methylation; Neoplasms; Prostatic Neoplasms; Ribonucleosides; RNA | 1983 |
Expression of endogenous murine leukemia virus in transplantable tumor cells and DNA methylation of the viral sequences.
Topics: Adenocarcinoma; Animals; Base Sequence; Breast Neoplasms; Cell Line; DNA Restriction Enzymes; Leukemia Virus, Murine; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Nucleic Acid Hybridization; RNA, Viral; Transplantation, Heterologous | 1984 |
Expression of cellular oncogenes in human malignancies.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Gene Amplification; Genes, Viral; Genital Neoplasms, Female; Humans; Kidney Neoplasms; Leukemia; Lymphoma; Methylation; Mutation; Neoplasms; Nucleic Acid Hybridization; Oncogenes; RNA, Messenger; RNA, Neoplasm; Sarcoma; Transcription, Genetic; Translocation, Genetic | 1984 |
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Gene methylation of oestrogen and epidermal growth factor receptors in neoplastic and perineoplastic breast tissues.
Topics: Breast Neoplasms; DNA; ErbB Receptors; Female; Humans; Methylation; Receptors, Estrogen | 1995 |
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3.
Topics: Amino Acid Sequence; Brain Neoplasms; Breast Neoplasms; Cell Division; Chromosomes, Human, Pair 17; Colonic Neoplasms; CpG Islands; Female; Fibroblasts; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Growth Inhibitors; Humans; Kruppel-Like Transcription Factors; Lung Neoplasms; Methylation; Molecular Sequence Data; Organ Specificity; Recombinant Proteins; Sequence Alignment; Transcription Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Zinc Fingers | 1995 |
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.
Topics: Base Sequence; Breast Neoplasms; Cadherins; DNA; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Molecular Sequence Data; Prostatic Neoplasms; Tumor Cells, Cultured | 1995 |
The presence of a trifluoromethyl rather than a methyl substituent in the bay-region greatly decreases the DNA-binding and tumour-initiating activity of the cyclopenta[alpha]phenanthren-17-ones.
Topics: Animals; Breast Neoplasms; Carcinogens; Cell Line; DNA; DNA Adducts; Epidermis; Female; Gonanes; Humans; Methylation; Mice; Mice, Inbred SENCAR; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Genomic sequencing indicates a correlation between DNA hypomethylation in the 5' region of the pS2 gene and its expression in human breast cancer cell lines.
Topics: Base Sequence; Breast Neoplasms; Cell Line; Clone Cells; Cloning, Molecular; DNA, Neoplasm; Estrogens; Gene Expression; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Proteins; Recombinant Proteins; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1995 |
DNA methylation status of the MUC1 gene coding for a breast-cancer-associated protein.
Topics: Adenocarcinoma; Alleles; Base Sequence; Breast Neoplasms; DNA, Neoplasm; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Mucin-1; Mucins; Neoplasm Proteins; Repetitive Sequences, Nucleic Acid; Spermatozoa; Transcription, Genetic | 1995 |
Regulation of gene expression involved in the progression of human breast cancer to hormone independence.
Topics: Azacitidine; Binding Sites; Breast Neoplasms; Cell Division; DNA; Epidermal Growth Factor; ErbB Receptors; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Methylation; Receptors, Estrogen; Tumor Cells, Cultured | 1993 |
Human breast and colon cancers exhibit alterations of DNA methylation patterns at several DNA segments on chromosomes 11p and 17p.
Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Calcitonin; Carcinoma in Situ; Carcinoma, Lobular; Catalase; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; Colonic Neoplasms; DNA; DNA, Neoplasm; Genes, ras; Globins; Humans; Intestinal Mucosa; Methylation; Parathyroid Hormone; Restriction Mapping | 1994 |
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase.
Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Estradiol; Humans; Methylation; Microsomes; Polychlorinated Dibenzodioxins; Steroid Hydroxylases; Tumor Cells, Cultured | 1994 |
Differentiation of primary and secondary breast cancer with clonal analysis.
Topics: Base Sequence; Breast Neoplasms; Diagnosis, Differential; Female; Gene Expression Regulation; Genes; Humans; Methylation; Middle Aged; Molecular Probes; Molecular Sequence Data; Neoplasms, Second Primary; Phosphoglycerate Kinase; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; X Chromosome | 1994 |
[Clonal analysis of human breast tumors by means of polymerase chain reaction].
Topics: Base Sequence; Breast; Breast Neoplasms; Female; Humans; Methylation; Molecular Sequence Data; Phosphoglycerate Kinase; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; X Chromosome | 1994 |
Binding of an ETS-related protein within the DNase I hypersensitive site of the HER2/neu promoter in human breast cancer cells.
Topics: Amino Acid Sequence; Base Sequence; Biomarkers, Tumor; Breast Neoplasms; Deoxyribonuclease I; DNA Primers; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Humans; Methylation; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Receptor, ErbB-2; Transcription Factors; Tumor Cells, Cultured; Ultraviolet Rays | 1994 |
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells.
Topics: Breast Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Female; Humans; Methylation; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 1994 |
Homozygous deletion, rearrangement and hypermethylation implicate chromosome region 3p14.3-3p21.3 in sporadic breast-cancer development.
Topics: Breast Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 3; DNA Probes; DNA Restriction Enzymes; DNA, Neoplasm; Female; Fibroadenoma; Gene Amplification; Gene Rearrangement; Genetic Variation; Humans; Methylation; Nucleic Acid Hybridization; Polymerase Chain Reaction | 1994 |
Hypopigmentation, anomalous cerebral dominance and seasonality.
Topics: Alzheimer Disease; Animals; Breast Neoplasms; Chromosomes, Human; DNA; Dominance, Cerebral; Dyslexia; Female; Gonadal Steroid Hormones; Humans; Hypopigmentation; Male; Maternal-Fetal Exchange; Methylation; Models, Biological; Prader-Willi Syndrome; Pregnancy; Rabbits; Seasons | 1993 |
Expression of Ca(2+)-binding proteins of the S100 family in malignant human breast-cancer cell lines and biopsy samples.
Topics: Breast Neoplasms; Calcium-Binding Proteins; Cell Cycle Proteins; Chromosomes, Human, Pair 1; Gene Rearrangement; Genes; Humans; In Vitro Techniques; Methylation; Multigene Family; S100 Calcium Binding Protein A6; S100 Calcium-Binding Protein A4; S100 Proteins; Tumor Cells, Cultured | 1994 |
The catalytic subunit of protein phosphatase 2A is carboxyl-methylated in vivo.
Topics: Amino Acid Sequence; Breast Neoplasms; Catalysis; Conserved Sequence; Female; Humans; Leucine; Methylation; Molecular Sequence Data; Oligopeptides; Phosphoprotein Phosphatases; Phosphorylase a; Phosphorylation; Protein Methyltransferases; Protein Phosphatase 2; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.
Topics: Adult; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cell Line; Child; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 9; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Dinucleoside Phosphates; DNA; DNA, Neoplasm; Female; Genes, Tumor Suppressor; Glioma; Homozygote; Humans; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphocytes; Male; Methylation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Reference Values; Restriction Mapping; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1996 |
Heterogenous point mutations in the BRCA1 breast cancer susceptibility gene occur in high frequency at the site of homonucleotide tracts, short repeats and methylatable CpG/CpNpG motifs.
Topics: Base Composition; Base Sequence; BRCA1 Protein; Breast Neoplasms; CpG Islands; DNA Transposable Elements; Female; Genetic Predisposition to Disease; Humans; Methylation; Microsatellite Repeats; Molecular Sequence Data; Mutagenesis; Mutation; Neoplasm Proteins; Oligodeoxyribonucleotides; Point Mutation; Sequence Deletion; Transcription Factors; Trinucleotide Repeats | 1996 |
Synthesis and growth inhibitory properties of glycosides of 1-O-hexadecyl-2-O-methyl-sn-glycerol, analogs of the antitumor ether lipid ET-18-OCH3 (edelfosine).
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Female; Glycosides; Humans; Indicators and Reagents; Leukemia L1210; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Methylation; Mice; Molecular Structure; Phospholipid Ethers; Tumor Cells, Cultured | 1996 |
Analysis of bcl-2 in sporadic breast carcinoma.
Topics: Blotting, Southern; Breast Neoplasms; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, p53; Humans; Loss of Heterozygosity; Methylation; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 1997 |
Lipotrope deficiency inhibits cell growth and induces programmed cell death in human breast cancer cell line MCF-7.
Topics: Amino Acids; Apoptosis; Breast Neoplasms; Cell Division; Choline Deficiency; DNA Fragmentation; Humans; Methylation; Vitamin B Deficiency | 1998 |
Hypermethylation of the Wilms' tumor suppressor gene CpG island in human breast carcinomas.
Topics: Breast Neoplasms; CpG Islands; Exons; Female; Genes, Wilms Tumor; Humans; Methylation; Promoter Regions, Genetic; Tumor Cells, Cultured | 1999 |
BRCA1 and E-cadherin promoter hypermethylation and gene inactivation in cancer-association or mechanism?
Topics: Breast Neoplasms; Cadherins; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Loss of Heterozygosity; Methylation; Mutation; Neoplasms; Ovarian Neoplasms; Promoter Regions, Genetic; Stomach Neoplasms | 2000 |
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Loss of Heterozygosity; Methylation; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Neoplasm; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Influence of the substitution of 11-methylene, delta(15), and/or 18-methyl groups in norethisterone on receptor binding, transactivation assays and biological activities in animals.
Topics: Animals; Biological Assay; Breast Neoplasms; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Female; Humans; Hydrocarbons; Injections, Subcutaneous; Ligands; Male; Methane; Methylation; Norethindrone; Orchiectomy; Organ Size; Ovarian Follicle; Ovulation; Progesterone; Prostate; Protein Binding; Rabbits; Rats; Receptors, Androgen; Receptors, Progesterone; Substrate Specificity; Transcriptional Activation; Tumor Cells, Cultured | 2000 |
Gene-expression profiles in hereditary breast cancer.
Topics: BRCA2 Protein; Breast Neoplasms; Female; Gene Expression; Genes, BRCA1; Genes, erbB-2; Humans; Methylation; Mutation; Neoplasm Proteins; Promoter Regions, Genetic; Transcription Factors | 2001 |
Early detection of malignant change in breast cells.
Topics: Breast; Breast Neoplasms; Female; Humans; Methylation; Polymerase Chain Reaction | 2001 |
Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms.
Topics: Alleles; Breast Neoplasms; Catechol O-Methyltransferase; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Enzyme-Linked Immunosorbent Assay; Estrogens, Catechol; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Methylation; Polymerase Chain Reaction; Recombinant Proteins; Tumor Cells, Cultured | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
Serum levels of N2, N2-dimethylguanosine and pseudouridine as determined by radioimmunoassay for patients with malignancy.
Topics: Antibody Specificity; Breast Neoplasms; Guanosine; Humans; Leukemia; Methylation; Neoplasms; Pseudouridine; Radioimmunoassay; Uridine | 1975 |
Superoxide dismutase activity and superoxide dismutase-1 gene methylation in normal and tumoral human breast tissues.
Topics: Breast; Breast Neoplasms; Carcinoma; DNA; DNA, Neoplasm; Exons; Female; Granulocytes; Humans; Isoenzymes; Leukocytes, Mononuclear; Methylation; Superoxide Dismutase | 1992 |
Polymorphism and altered methylation of the lactoferrin gene in normal leukocytes, leukemic cells, and breast cancer.
Topics: Amino Acid Sequence; Breast Neoplasms; Gene Library; Genes; Humans; Lactoferrin; Leukemia; Leukocytes; Methylation; Molecular Sequence Data; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length | 1991 |
Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas.
Topics: Adult; Aged; Blotting, Southern; Breast Neoplasms; DNA; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Methylation; Middle Aged; Neoplasm Metastasis; Nuclear Proteins; Proto-Oncogene Proteins; Receptor, ErbB-2; Restriction Mapping; Uterine Cervical Neoplasms | 1991 |
Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor.
Topics: Adenofibroma; Adult; Aged; Aged, 80 and over; Base Sequence; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Middle Aged; Nucleic Acid Hybridization; Receptors, Estrogen; Restriction Mapping | 1990 |
Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer.
Topics: Biomarkers; Breast Neoplasms; Erythrocyte Membrane; Fatty Acids; Female; Gas Chromatography-Mass Spectrometry; Humans; Membrane Lipids; Menopause; Methylation; Phospholipids; Reference Values | 1990 |
Estrogen receptor gene methylation in human breast tumors.
Topics: Blotting, Southern; Breast; Breast Neoplasms; DNA; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Methylation; Receptors, Estrogen | 1990 |
Alterations in the X chromosome replication pattern induced by 5-azacytidine in a human tumor line.
Topics: Azacitidine; Breast Neoplasms; Cell Line; Chromosome Banding; DNA Replication; Dosage Compensation, Genetic; Gene Expression Regulation; Humans; Methylation; X Chromosome | 1986 |
Transcriptional control of thymidine kinase gene expression by estrogen and antiestrogens in MCF-7 human breast cancer cells.
Topics: Amanitins; Breast Neoplasms; Cell Cycle; Cell Line; DNA; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation; Humans; Methylation; Pyrrolidines; RNA; RNA, Messenger; Tamoxifen; Thiophenes; Thymidine; Thymidine Kinase; Time Factors | 1986 |
Incorporation of 5-fluorodeoxycytidine and metabolites into nucleic acids of human MCF-7 breast carcinoma cells.
Topics: Azacitidine; Breast Neoplasms; Cell Line; Cell Survival; Decitabine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Humans; Methylation; RNA, Neoplasm; Tetrahydrouridine | 1986 |
Structures of O-linked oligosaccharides present in the proteoglycans secreted by human mammary epithelial cells.
Topics: Adenocarcinoma; Borohydrides; Breast; Breast Neoplasms; Carbohydrate Conformation; Cell Line; Chromatography, Gel; Electrophoresis, Paper; Epithelium; Female; Glycoside Hydrolases; Humans; Indicators and Reagents; Methylation; Oligosaccharides; Oxidation-Reduction; Periodic Acid; Proteoglycans | 1986 |
No loss of estrogenic or anti-estrogenic activity after demethylation of droloxifene (3-OH-tamoxifen).
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Estrogen Antagonists; Female; Humans; Methylation; Rats; Receptors, Estrogen; Tamoxifen; Uterus | 1985 |