Page last updated: 2024-08-18

isomethyleugenol and Astrocytoma, Grade IV

isomethyleugenol has been researched along with Astrocytoma, Grade IV in 134 studies

Research

Studies (134)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.75)18.7374
1990's6 (4.48)18.2507
2000's16 (11.94)29.6817
2010's69 (51.49)24.3611
2020's42 (31.34)2.80

Authors

AuthorsStudies
Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Jefferies, S; Kelly, C; Kurian, KM; McAleenan, A; Schmidt, L; Spiga, F; Wragg, C1
Li, H; Li, X; Lu, J1
Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A1
Hölzl, D; Kral, M; Kraus, TFJ; Ladisich, B; Machegger, L; Pöppe, J; Schlicker, HU; Schwartz, C; Sotlar, K; Spendel, M; Zellinger, B1
French, PJ; Golfinopoulos, V; Gorlia, T; Tesileanu, CMS; van den Bent, MJ1
Fan, J; Li, C; Wan, B; Wang, S; Xiong, W; Zhang, Y; Zheng, Z1
Hase, H; Hirade, Y; Kitae, K; Takahashi, H; Tashiro, J; Tsujikawa, K; Yoshida, T1
Cao, D; Huang, W; Su, Y; Xing, Z; Yang, X; Zhou, X1
Cao, H; Chao, M; Chen, F; Wang, L; Xie, X1
Dong, W; Liu, L; Liu, M; Liu, X; Ruan, X; Wang, D; Wang, P; Xue, Y; Yang, C; Zhang, M1
Liu, M; Liu, Q; Liu, R; Sun, G; Xu, B; Zhao, K1
Chen, Y; Lan, Q; Li, P; Li, Y; Li, Z; Wang, J; Wang, Q; Wang, Y; Wang, Z; Wu, C; Xiao, Z; Zhou, H1
Birkl-Toeglhofer, AM; Brawanski, KR; Freyschlag, CF; Haybaeck, J; Hoeftberger, R; Manzl, C; Sprung, S; Ströbel, T; Thomé, C1
Cui, J; Dong, W; Liu, L; Liu, X; Liu, Y; Ruan, X; Wang, P; Xue, Y; Zhang, M1
Angelini, C; Caccese, M; Cavallin, F; Cerretti, G; Chioffi, F; d'Avella, D; De Bonis, P; De Rossi, A; Giunco, S; Lombardi, G; Morello, M; Padovan, M; Puppa, AD; Rizzo, B; Zagonel, V1
Alafandi, A; Gorlia, T; Klein, S; Nabors, L; Rizopoulos, D; Smits, M; Stupp, R; Tonn, JC; van der Voort, SR; van Garderen, KA; Weller, M1
Chen, J; Chen, Y; Huang, H; Lan, C; Li, C; Li, X; Liu, C; Liu, W; Luo, K; Luo, Q; Qin, J; Tan, R; Wang, X; Wei, C; Wei, S; Zhang, G; Zheng, C1
Harter, PN; Herms, J; Katzendobler, S; Niedermeyer, S; Niyazi, M; Stoecklein, VM; Thon, N; Tonn, JC; Trumm, C; Weller, J1
Gao, Z; Hu, R; Li, M; Li, Y; Liu, C; Mei, M; Pang, B; Ren, Y; Wang, Y; Yang, J; Zhang, B; Zhang, X; Zhou, X1
Ferrer, VP; Machado, GC1
Deng, X; Gao, X; Hu, Z; Huang, Y; Sun, J; Sun, X; Wu, Y; Zhou, C1
Bruce, JN; Canoll, PD; Cheng, SK; Gill, BJA; Grinband, J; Horowitz, DP; Iwamoto, FM; Kachnic, LA; Kinslow, CJ; Kumar, P; McKhann, GM; Neugut, AI; Rae, AI; Siegelin, MD; Sisti, MB; Taparra, K; Wang, TJC; Yu, JB1
Camenisch Gross, U; Hofer, S; Lehnick, D; Leske, H; Leske, S; Neidert, MC; Rushing, EJ; Weller, M1
Alasmawi, H; Ridzuan, M; Saeed, N; Sobirov, I; Yaqub, M1
Chen, R; Chen, X; Gimple, RC; Jiang, T; Lin, P; Liu, L; Liu, Q; Liu, X; Liu, Z; Luo, J; Prager, BC; Rich, JN; Wang, D; Wu, E; Wu, Q; Wu, W; Xie, Q; Yu, J; Zhang, W; Zhang, Y; Zhao, W1
Bahador, M; Bifulco, E; Bindesbøll, C; Brekke, J; Chekenya, M; Engelsen, A; Enger, PØ; Gjertsen, BT; Goplen, D; Gras Navarro, A; Lie, SA; Rahman, MA; Sarowar, S; Selheim, F; Simonsen, A; Waha, A1
Berglund, AE; Etame, AB; MacAulay, RJ; Mulé, JJ; Wang, D; Wu, Q1
Acker, T; Becker, A; Brandner, S; Brokinkel, B; Buslei, R; Capper, D; Casalini, MB; Deckert, M; Dohmen, H; Ebrahimi, A; Felsberg, J; Fernández-Klett, F; Gramatzki, D; Hänggi, D; Hans, VH; Hartmann, C; Herold-Mende, C; Heß, K; Hewer, E; Huang, K; Jaunmuktane, Z; Jones, DTW; Koelsche, C; Korshunov, A; Mawrin, C; Paulus, W; Pfister, SM; Platten, M; Pohl, U; Prinz, M; Reifenberger, G; Reinhardt, A; Reuss, DE; Sahm, F; Schittenhelm, J; Schrimpf, D; Sievers, P; Staszewski, O; Stichel, D; Suwala, A; Unterberg, A; von Deimling, A; Wefers, AK; Weller, M; Wick, W1
Favia, A; Fontanella, RA; Illi, B; Iwamoto-Stohl, LK; Mai, A; Nanni, S; Nasi, S; Salvatori, L; Scagnoli, F; Totta, P; Valente, S1
Ichimura, K; Igaki, H; Matsushita, Y; Miyakita, Y; Narita, Y; Ohno, M; Takahashi, M1
Carrato, A; Esteban, J; Gutiérrez, JA; Ley, L; Torres, J; Vaz Salgado, MA1
Ahmadipour, Y; Gembruch, O; Jabbarli, R; Pierscianek, D; Sure, U1
Ciafrè, SA; Galardi, S; Michienzi, A1
Chen, H; Chen, W; Ge, J; Guo, L; Hou, G; Mao, Q; Yang, J; Zhang, X1
Arita, H; Fukai, J; Kanematsu, D; Kanemura, Y; Kinoshita, M; Kodama, Y; Mano, M; Mori, K; Nakao, N; Nonaka, M; Okita, Y; Sakamoto, D; Shofuda, T; Tsuyuguchi, N; Uda, T; Uematsu, Y; Umehara, T; Yoshioka, E1
Brinkmann, DH; Herman, MG; Hunt, CH; Kemp, BJ; Laack, NN; Lowe, V; Pafundi, DH; Qian, J1
Chen, WJ; Han, H; He, XS; Kang, EM; Liu, WP; Lv, JN; Wang, GH; Wang, J; Yu, YB; Zhang, W; Zhang, X; Zhang, YL1
Cheng, H; Dai, X; Hu, Y; Wang, H; Wang, J; Wu, B; Ye, L1
van der Hoorn, A; van Dijken, BRJ1
Caselli, M; Dührsen, L; Felce, JH; Fita, KD; Fuh, MM; Glatzel, M; Görgens, A; Heiland, DH; Jones, JC; Joosse, SA; Kaulich, K; Lamszus, K; Maire, CL; Miklosi, AG; Pantel, K; Pereno, V; Reifenberger, G; Reimer, R; Ricklefs, FL; Ricklefs, T; Sauvigny, T; Schlüter, H; Schüller, U; Stevic, I; Welsh, JA; Westphal, M1
Chen, JS; Fajardo, JE; Fiser, A; Guetta-Terrier, C; Karambizi, D; Sarkar, A; Snyder, KM; Tang, OY; Tapinos, N; Toms, SA; Zepecki, JP1
Clarke, PR1
Anderson, SK; Brinkmann, D; Brown, P; Hunt, C; Kabat, B; Kaufmann, T; Kemp, B; Kizilbash, S; Laack, NN; Lowe, V; Pafundi, D; Ruff, M; Sarkaria, J; Seaberg, M; Uhm, J; Vogen, D; Wan Chan Tseung, HS; Yan, E; Zakhary, M; Zhang, Y1
Kleszcz, R; Krajka-Kuźniak, V; Kruhlenia, N; Majchrzak-Celińska, A; Misiorek, JO; Przybyl, L; Rolle, K1
Oudenaarden, C; Pietras, K; Sjölund, J1
Alirezaei, Z; Amouheidari, A; Ghahremani, F; Kefayat, A1
Bronsema, A; Guerreiro, H; Kresbach, C; Rutkowski, S; Schüller, U; Winkler, B1
Cutts, SM; Nudelman, A; Rephaeli, A; Rozic, G; Tarasenko, N1
Dixit, D; Rich, JN; Xie, Q; Zhao, JC1
Bartom, E; Bi, Y; Burant, CF; Calvert, AE; Chalastanis, A; Chandel, NS; Davuluri, RV; Dubrovskyi, O; Horbinski, C; Hua, Y; Hurley, LA; James, CD; Kachman, M; Kouri, FM; May, JL; Mazar, AP; Mishra, RK; Peter, ME; Schiltz, GE; Stegh, AH; Wu, Y; Zheng, H1
Back, M; Brazier, D; Cook, R; Gzell, C; Harris, G; Jayamanne, D; Kastelan, M; Khasraw, M; Louw, S; Parkinson, J; Schembri, G; Wheeler, H1
Chen, Y; Jiang, S; Peng, Y; Zhong, S1
Bender, B; Bier, G; Brendle, C; Castaneda Vega, S; Ernemann, U; Hempel, JM; Klose, U; Schittenhelm, J; Skardelly, M; Tabatabai, G1
Battenhouse, AM; Cowperthwaite, MC; Hall, AW; Iyer, VR; Morris, AR; Shivram, H; Shpak, M1
Ishikawa, H; Izumikawa, K; Simpson, RJ; Takahashi, N1
Li, W; Shi, J; Shi, L; Shi, X; Wen, H1
Han, P; Lee, A; Malakhov, N; Schreiber, D; Sheth, N; Wang, A1
Bähr, O; Belka, C; Braun, C; Gerlach, R; Glas, M; Goldbrunner, R; Hänel, M; Hattingen, E; Hau, P; Herrlinger, U; Junold, N; Kebir, S; Kortmann, RD; Krex, D; Mack, F; Niessen, M; Proescholdt, M; Rohde, V; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schmidt-Graf, F; Steinbach, JP; Stuplich, M; Tzaridis, T; Vatter, H; Weyerbrock, A1
Bao, L; Chen, Y; Chiang, CM; Fontenot, M; Hatanpaa, KJ; Lai, HT; Lega, B; Luo, W; Raisanen, JM; Semenza, GL; Wang, JE; Wang, Y; Wu, SY1
Ai, C; Dong, F; Gao, W; Huo, D; Kang, C; Kong, Y; Li, Q; Li, W; Liu, W; Liu, X; Sun, X; Wang, W; Wang, X; Wu, X; Yang, C; Zhou, Y1
Abril, L; Archila, P; Arrieta, O; Balaña, C; Behaine, J; Bermúdez, S; Cardona, AF; Carranza, H; Cifuentes, H; Feo, O; González, D; Hakim, F; Jacobo, J; Jiménez, E; Mantilla, MI; Marquez, JC; Mejía, JA; Ortiz, LD; Otero, J; Penagos, P; Pineda, D; Pino, LE; Ramón, JF; Ricaurte, L; Rodríguez, J; Rojas, L; Rosell, R; Ruiz-Patiño, A; Useche, N; Vargas, C; Wills, B; Zatarain-Barrón, ZL1
Cantero, D; de Velasco, G; Hernández-Laín, A; Hilario, A; Manneh Kopp, RA; Pérez Núñez, A; Ramos, A; Ruano, Y; Sánchez-Gómez, P; Sepúlveda-Sánchez, JM; Toldos, O1
Boldt, HB; Dahlrot, RH; Hansen, S; Hjelmborg, JB; Kreutzfeldt, MS; Kristensen, BW; Larsen, P1
Cai, J; Cao, L; Chen, Z; Gu, J; Guo, C; Li, C; Liang, J; Lin, Y; Liu, X; Liu, Y; Lu, B; Lu, W; Mai, J; Ou-Yang, Y; Qiu, P; Sai, K; Sheng, L; Su, X; Sun, H; Sun, S; Tan, Y; Wang, J; Xing, F; Xue, D; Yan, G; Yang, X; Yin, W; Zhu, W; Zhu, Z1
Bhargava, S; Bi, J; Brown, JM; Cang, H; Dong, Z; Gimple, RC; Gromovsky, AD; Huan, T; Jiang, L; Kidwell, RL; Kim, LJY; Lee, D; Lv, D; Mack, SC; Mischel, PS; Prager, BC; Rich, JN; Sloan, AE; Sun, T; Wang, X; Wolf, M; Wu, Q; Xie, Q; Ye, Q; Zhang, G; Zhao, L; Zhu, Z1
Allis, CD; Banaszynski, LA; Becher, OJ; Cordero, F; Garcia, BA; Koletsky, MS; Lewis, PW; Lin, S; Muir, TW; Müller, MM1
Chen, W; Chen, Y; Hu, F; Shao, H; Zhang, Y; Zhou, Y1
Chang, N; Joo, KM; Kim, E; Kim, H; Kim, M; Lee, C; Lee, J; Nakano, I; Nam, DH; Oh, YT; Rheey, J; Rich, JN; Shin, J; Shin, Y; Woo, DH1
Attar, R; Biray Avci, C; Caglar, HO; Dalbasti, T; Gunduz, C; Haydaroglu, A; Kitapcioglu, G; Oktar, N; Yurtsever, A1
Adamopoulos, C; Dalagiorgou, G; Gargalionis, A; Lea, RW; Papavassiliou, AG; Papavassiliou, KA; Piperi, C; Spyropoulou, A1
Abrams, JS; Conley, BA; Freidlin, B; Korn, EL; McShane, LM; Polley, MY1
Bender, S; Castel, D; Chen, S; Cho, YJ; Collins, VP; Ebinger, M; Grill, J; Gronych, J; Helin, K; Hovestadt, V; Højfeldt, JW; Jabado, N; Johann, PD; Jones, C; Jones, DT; Kool, M; Korshunov, A; Lichter, P; Lindroth, AM; Meyer, J; Milde, T; Monje, M; Monoranu, CM; Northcott, PA; Pfister, SM; Plass, C; Ponnuswami, A; Puget, S; Radlwimmer, B; Ryzhova, M; Schubert, S; Schuhmann, M; Seker-Cin, H; Stark, S; Sturm, D; Tang, Y; Truffaux, N; von Deimling, A; Wang, W; Witt, O; Zapatka, M1
Chamberlain, MC1
Bond, F; Bridges, LR; Burke, E; Crocker, M; Elderfield, K; Grobler, M; Taylor, R1
Balañà, C; Capdevila, L; Carrato, C; Cros, S; Cuadra, JL; Etxaniz, O; Hostalot, C; Massuet, A; Ramirez, JL; Romeo, M; Sanz, C; Villà, S1
Bauer, R; Bernaskova, M; Huefner, A; Kretschmer, N; Schuehly, W; Weis, R1
Cui, X; Nenoi, M; Ninomiya, Y; Sekine-Suzuki, E; Wang, B; Yasuda, T; Yu, D1
Bähr, O; Braczynski, AK; Dunst, M; Eibach, S; Harter, PN; Hattingen, E; Mittelbronn, M; Plate, KH; Rieger, J; Seifert, V; Steinbach, JP; Weise, LM1
Akiyama, T; Ino, Y; Katou, Y; Koyama-Nasu, R; Kozuka-Hata, H; Masuda, K; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Ogawa, H; Oyama, M; Saito, N; Sakaguchi, Y; Sato, T; Shirahige, K; Suzuki, T; Takai, H; Todo, T; Toyoshima, C1
Berghoff, AS; Hainfellner, JA; Marosi, C; Preusser, M1
Adamopoulos, C; Boviatsis, E; Dalagiorgou, G; Gargalionis, A; Korkolopoulou, P; Levidou, G; Patsouris, E; Petraki, K; Piperi, C; Samaras, V; Sepsa, A; Spyropoulou, A; Themistocleous, MS; Thymara, I; Vrettakos, G; Zisakis, A1
Cai, Q; Chen, Q; Daofeng, T; Dong, H; Guo, Z; Ji, B; Liu, B; Liu, Y; Wang, J; Wang, L; Wu, L; Zhang, S; Zhu, X1
Cloughesy, TF; Ha, W; Hitchins, MP; Lai, A; McDonald, KL; Nguyen, HN; Nowak, AK; Rapkins, RW; Wang, F1
Benecke, R; Grossmann, A; Hildebrandt, G; Kirschstein, T; Piek, J; Rösche, J1
Motomura, K; Natsume, A; Ohka, F; Ranjit, M; Wakabayashi, T1
Bartoli, L; Beji, S; Falchetti, ML; Farsetti, A; Favia, A; Illi, B; Levi, A; Mongiardi, MP; Nanni, S; Nasi, S; Savino, M; Scagnoli, F1
Mohile, NA1
Capper, D; Franco, P; Grauvogel, J; Heiland, DH; Hirsch, M; Masalha, W; Schrimpf, D; Staszewski, O; Urbach, H; Weyerbrock, A1
Luo, D; Luo, K; Wen, H1
Cui, HJ; Huang, MY; Liu, W; Xuan, F1
Choi, SH; Heo, DS; Jung, HW; Kim, DG; Kim, IH; Kim, SK; Kim, TM; Lee, SH; Lee, ST; Park, CK1
Balvers, RK; Dirven, CM; Lamfers, ML; Leenstra, S1
Drummond, KJ; Kaye, AH; Paldor, I; Pearce, FC1
Aster, JC; Bernstein, BE; Cahill, DP; Carey, CD; Donohue, LK; Flavahan, WA; Gillespie, SM; Hebert, CH; Liau, BB; Miller, TE; Najm, FJ; Patel, AP; Rich, JN; Rodig, SJ; Shareef, SJ; Sievers, C; Suvà, ML; van Galen, P; Venteicher, AS; Wakimoto, H1
Ando, N; Dong, X; Kobayashi, D; Maehara, T; Sumita, K; Tamura, K1
Berger, MS; Lin, C; Lin, CA; Phillips, JJ; Rhodes, CT1
Cui, Q; He, C; Huang, Y; Li, L; Lu, Z; Qu, Q; Riggs, AD; Shi, H; Shi, Y; Sun, G; Yang, CG; Ye, P1
Del Maestro, R; Guiot, MC; Kavan, P; Lambert, C; Leblanc, R; Muanza, T; Panet-Raymond, V; Roberge, D; Shakibnia, L; Shenouda, G; Souhami, L1
Bian, X; Chen, K; Dunlop, NM; Gao, Y; Gong, W; Howard, OM; Huang, J; Wang, JM1
Jaskolski, D; Jesien-Lewandowicz, E; Jesionek-Kupnicka, D; Kordek, R; Kulczycka-Wojdala, D; Liberski, PP; Och, W; Papierz, W; Potemski, P; Rieske, P; Sieruta, M; Sikorska, B; Skowronski, W; Szybka, M; Zawlik, I1
Haapasalo, H; Hahn, WC; Hector, ME; Junttila, MR; Kast, J; Ketola, K; Lin, S; Puustinen, P; Raheem, O; Sablina, AA; Teittinen, K; Vanhatupa, S; Westermarck, J1
Addeo, R; Caraglia, M; De Santi, MS; Del Prete, S1
Ballman, KA; Carlson, BL; Decker, PA; Giannini, C; Grogan, PT; James, CD; Kitange, GJ; Mladek, AC; Sarkaria, JN; Schroeder, MA; Wu, W1
Berger, H; Felsberg, J; Hartmann, C; Heese, O; Krex, D; Loeffler, M; Nikkhah, G; Pietsch, T; Reifenberger, G; Schackert, G; Schramm, J; Simon, M; Steinbach, JP; Tonn, JC; von Deimling, A; Weller, M; Westphal, M; Wiestler, O1
Carapella, CM; Carosi, M; Cognetti, F; Fabi, A; Giannarelli, D; Maschio, M; Metro, G; Mirri, MA; Pace, A; Pellegrini, D; Pompili, A; Russillo, M; Vidiri, A1
Agarwal, N; Ahluwalia, MS; Barnett, GH; Brewer, CJ; Elson, P; Peereboom, DM; Shepard, DR; Stevens, GH; Suh, JH; Toms, SA; Vogelbaum, MA; Weil, RJ1
Blechschmidt, C; Czabanka, M; Koch, A; Misch, M; Plotkin, M; Stockhammer, F; Tuettenberg, J; Vajkoczy, P1
Furuyama, N; Hamada, J; Hayashi, Y; Kamide, T; Nakada, M; Nakada, S; Sawada-Kitamura, S; Suzuki, T; Tanaka, S; Yano, S1
Fukushima, T; Katayama, Y; Nagase, H; Ohta, T; Shinojima, Y; Terui, T; Watanabe, T; Yachi, K; Yoshino, A1
Amano, T; Araki, Y; Iwaki, T; Mizoguchi, M; Nakamizo, A; Sasaki, T; Shono, T; Suzuki, SO; Yoshimoto, K1
Agnihotri, S; Guha, A; Munoz, D; Wolf, A1
Hirose, Y; Kanai, R; Louis, DN; Martuza, RL; Rabkin, SD; Sgubin, D; Wakimoto, H; Yip, S; Zaupa, CM1
Chatzisotiriou, A; Eleftheraki, AG; Fountzilas, G; Iliadis, G; Kotoula, V; Lambaki, S; Misailidou, D; Selviaridis, P; Televantou, D1
Ewelt, C; Felsberg, J; Jakobs, O; Martus, P; Meinel, T; Reifenberger, G; Stummer, W1
Batchelor, TT; Louis, DN; Sorensen, AG1
Carlson, BL; Cen, L; Decker, PA; Gupta, SK; Kitange, GJ; Lomberk, GA; Mladek, AC; Pokorny, JL; Sarkaria, JN; Schroeder, MA; Urrutia, RA; Wu, W1
Hamada, J; Hayashi, Y; Kato, Y; Nakada, M; Ooi, A; Sabit, H; Sato, H; Suzuki, S; Watanabe, T; Yoshikawa, A1
Laird, PW; Marczinek, K; Nürnberg, P; Rohde, K; Szymas, J; Thiel, G; Uhlmann, K; Vogel, S; Zeller, C1
Baeza, N; Kleihues, P; Ohgaki, H; Weller, M; Yonekawa, Y1
Berger, MS; Hirose, Y; Katayama, M; Mirzoeva, OK; Pieper, RO1
Altundag, K; Altundag, MB; Altundag, O; Boruban, C; Turen, S1
Ishida, E; Konishi, N; Nakamura, M; Nakase, H; Sakaki, T; Shimada, K1
Aldape, K; Black, PM; Chakravarti, A; Erkkinen, MG; Gilbert, MR; Loeffler, JS; Mehta, M; Nestler, U; Stupp, R1
Auger, N; Benouaich-Amiel, A; Crinière, E; Delattre, JY; Everhard, S; Hoang-Xuan, K; Kaloshi, G; Laigle-Donadey, F; Lejeune, J; Mokhtari, K; Polivka, M; Sanson, M; Thillet, J1
Cankovic, M; Mikkelsen, T; Rosenblum, ML; Zarbo, RJ1
Hau, P; Hegi, ME; Stupp, R1
Campain, JA; Cox, GS; Gutkin, DW1
Bourgeois, CA; Delattre, JY; Dutrillaux, AM; Dutrillaux, B; Kokalj-Vokac, N; Malfoy, B; Poisson, M; Vega, F1
Christensen, B; Fiskerstrand, T; Refsum, H; Tysnes, OB; Ueland, PM1
Baylin, SB; Brodeur, GM; Cavenee, WK; Chazin, VR; Makos, M; Nelkin, BD1
Berger, MS; Cavenee, WK; Costello, JF; Huang, HS1
Akhtar, S; Fell, PL; Hudson, AJ; Reynolds, MA; Usman, N1
Viale, GL1

Reviews

12 review(s) available for isomethyleugenol and Astrocytoma, Grade IV

ArticleYear
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
    Neuro-oncology, 2021, 09-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Glioma; Humans; Methylation; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2021
A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature.
    Brain tumor pathology, 2022, Volume: 39, Issue:2

    Topics: Astrocytoma; Biology; Brain Neoplasms; Chromosomes, Human, Pair 1; DNA; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Oligodendroglioma

2022
The Potential Value of m6A RNA Methylation in the Development of Cancers Focus on Malignant Glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Glioblastoma; Glioma; Humans; Methylation; RNA; Tumor Microenvironment

2022
Insights into the Regulatory Role of m
    International journal of molecular sciences, 2020, Apr-17, Volume: 21, Issue:8

    Topics: Adenosine; Brain Neoplasms; Cytosine; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; RNA, Ribosomal, 28S

2020
Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.
    RNA biology, 2018, Volume: 15, Issue:7

    Topics: Animals; Arginine; beta-Thalassemia; Glioblastoma; Humans; Introns; Methylation; Mice; Nonsense Mediated mRNA Decay; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA Splicing; RNA, Messenger; Transcription Factors; Transcription, Genetic

2018
MGMT promoter methylation and glioblastoma prognosis: a systematic review and meta-analysis.
    Archives of medical research, 2013, Volume: 44, Issue:4

    Topics: Brain Neoplasms; Disease-Free Survival; DNA Methylation; Genetic Heterogeneity; Glioblastoma; Humans; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic

2013
Assessing MGMT methylation status and its current impact on treatment in glioblastoma.
    CNS oncology, 2015, Volume: 4, Issue:1

    Topics: Brain Neoplasms; DNA Modification Methylases; Glioblastoma; Humans; Methylation

2015
Applicable advances in the molecular pathology of glioblastoma.
    Brain tumor pathology, 2015, Volume: 32, Issue:3

    Topics: Basic Helix-Loop-Helix Transcription Factors; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cyclin-Dependent Kinase Inhibitor p16; DNA Helicases; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Gene Deletion; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Isocitrate Dehydrogenase; Methylation; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Oligodendrocyte Transcription Factor 2; Promoter Regions, Genetic; Receptor, Platelet-Derived Growth Factor alpha; Telomerase; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; X-linked Nuclear Protein

2015
How I treat glioblastoma in older patients.
    Journal of geriatric oncology, 2016, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Geriatric Assessment; Glioblastoma; Humans; Isocitrate Dehydrogenase; Methylation; Middle Aged; Prognosis; Promoter Regions, Genetic; Quality of Life; Seizures; Standard of Care; Temozolomide; Tumor Suppressor Proteins

2016
Malignant Glioma In Vitro Models: On the Utilization of Stem-like Cells.
    Current cancer drug targets, 2017, Volume: 17, Issue:3

    Topics: Biopsy; Cell Culture Techniques; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Neoplastic Stem Cells; Tumor Cells, Cultured

2017
Progressive adult primary glioblastoma in the medulla oblongata with an unmethylated MGMT promoter and without an IDH mutation.
    Brain tumor pathology, 2013, Volume: 30, Issue:3

    Topics: Brain Neoplasms; Chemoradiotherapy; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Fatal Outcome; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Imaging; Medulla Oblongata; Methylation; Middle Aged; Mutation; Promoter Regions, Genetic; Tumor Suppressor Proteins

2013
MGMT methylation status: the advent of stratified therapy in glioblastoma?
    Disease markers, 2007, Volume: 23, Issue:1-2

    Topics: Animals; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Glioblastoma; Humans; Methylation; Tumor Suppressor Proteins

2007

Trials

5 trial(s) available for isomethyleugenol and Astrocytoma, Grade IV

ArticleYear
Initial Results of a Phase 2 Trial of
    International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition; Confidence Intervals; Dihydroxyphenylalanine; Dose Fractionation, Radiation; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Positron-Emission Tomography; Progression-Free Survival; Prospective Studies; Quality of Life; Radiopharmaceuticals; Radiotherapy, Image-Guided; Temozolomide; Young Adult

2021
Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cell Growth Processes; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiotherapy; Temozolomide; Tumor Suppressor Proteins

2018
Neoadjuvant cisplatin plus temozolomide versus standard treatment in patients with unresectable glioblastoma or anaplastic astrocytoma: a differential effect of MGMT methylation.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Male; Methylation; Middle Aged; Neoadjuvant Therapy; Radiation-Sensitizing Agents; Retrospective Studies; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; Young Adult

2014
Phase II study of fixed dose rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma multiforme.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Deoxycytidine; DNA Modification Methylases; DNA Repair Enzymes; Female; Gemcitabine; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Radiation-Sensitizing Agents; Tumor Suppressor Proteins

2010
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2010, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Erlotinib Hydrochloride; Female; Glioblastoma; Humans; Karnofsky Performance Status; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Radiotherapy; Temozolomide; Tumor Suppressor Proteins; Young Adult

2010

Other Studies

117 other study(ies) available for isomethyleugenol and Astrocytoma, Grade IV

ArticleYear
Perfusion parameters derived from MRI for preoperative prediction of IDH mutation and MGMT promoter methylation status in glioblastomas.
    Magnetic resonance imaging, 2021, Volume: 83

    Topics: Brain Neoplasms; Diffusion Magnetic Resonance Imaging; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Imaging; Methylation; Mutation; Perfusion; Retrospective Studies; Tumor Suppressor Proteins

2021
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glioblastoma; Histones; Humans; Injections, Intraperitoneal; Lomustine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2021
MGMT promoter methylation determined by the MGMT-STP27 algorithm is not predictive for outcome to temozolomide in IDH-mutant anaplastic astrocytomas.
    Neuro-oncology, 2022, 04-01, Volume: 24, Issue:4

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Methylation; Temozolomide; Tumor Suppressor Proteins

2022
N6-Methyladenosine Regulator-Mediated Immue Patterns and Tumor Microenvironment Infiltration Characterization in Glioblastoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenosine; Glioblastoma; Humans; Methylation; Tumor Microenvironment

2022
Discovery of two novel ALKBH5 selective inhibitors that exhibit uncompetitive or competitive type and suppress the growth activity of glioblastoma multiforme.
    Chemical biology & drug design, 2022, Volume: 100, Issue:1

    Topics: AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Glioblastoma; Humans; Methylation; RNA

2022
Non-invasive prediction of p53 and Ki-67 labelling indices and O-6-methylguanine-DNA methyltransferase promoter methylation status in adult patients with isocitrate dehydrogenase wild-type glioblastomas using diffusion-weighted imaging and dynamic suscept
    Clinical radiology, 2022, Volume: 77, Issue:8

    Topics: Adult; Brain Neoplasms; DNA; Glioblastoma; Guanine; Humans; Isocitrate Dehydrogenase; Ki-67 Antigen; Magnetic Resonance Imaging; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Perfusion; Retrospective Studies; Tumor Suppressor Protein p53

2022
The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells.
    Cell death & disease, 2022, 12-03, Volume: 13, Issue:12

    Topics: Animals; Cyclin-Dependent Kinases; DNA-Binding Proteins; Glioblastoma; Methylation; Methyltransferases; Mice; Mice, Nude; Microcirculation; Neovascularization, Pathologic; Phosphorylation; RNA-Binding Proteins; RNA, Messenger

2022
MR Imaging, MGMT Promoter Methylation Features and Prognostic Analysis of Subventricular Zone Contacting IDH Wild-type Glioblastoma.
    Current medical imaging, 2023, Volume: 19, Issue:12

    Topics: Adult; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Lateral Ventricles; Magnetic Resonance Imaging; Methylation; Prognosis; Retrospective Studies; Tumor Suppressor Proteins

2023
PRMT6-CDC20 facilitates glioblastoma progression via the degradation of CDKN1B.
    Oncogene, 2023, Volume: 42, Issue:14

    Topics: Cdc20 Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Glioblastoma; Histones; Humans; Methylation; Nuclear Proteins; Protein-Arginine N-Methyltransferases

2023
Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Mismatch Repair; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Progression-Free Survival; Temozolomide; Tumor Suppressor Proteins

2023
SNORD17-mediated KAT6B mRNA 2'-O-methylation regulates vasculogenic mimicry in glioblastoma cells.
    Cell biology and toxicology, 2023, Volume: 39, Issue:6

    Topics: Animals; Cell Line, Tumor; Glioblastoma; Histone Acetyltransferases; Humans; Methylation; Mice; Mice, Nude; RNA, Messenger

2023
Prognostic role and interaction of TERT promoter status, telomere length and MGMT promoter methylation in newly diagnosed IDH wild-type glioblastoma patients.
    ESMO open, 2023, Volume: 8, Issue:3

    Topics: Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Isocitrate Dehydrogenase; Methylation; Prognosis; Prospective Studies; Retrospective Studies; Telomerase; Telomere; Tumor Suppressor Proteins

2023
Association of pre-radiotherapy tumour burden and overall survival in newly diagnosed glioblastoma adjusted for MGMT promoter methylation status.
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 188

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Methylation; Prognosis; Retrospective Studies; Tumor Burden; Tumor Suppressor Proteins

2023
Integrating machine learning and bioinformatics analysis to m6A regulator-mediated methylation modification models for predicting glioblastoma patients' prognosis and immunotherapy response.
    Aging, 2023, 05-23, Volume: 15, Issue:10

    Topics: Computational Biology; Glioblastoma; Humans; Immunotherapy; Machine Learning; Methylation; Prognosis; Tumor Microenvironment

2023
Treatment benefit in patients aged 80 years or older with biopsy-proven and non-resected glioblastoma is dependent on MGMT promoter methylation status.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Methylation; Prognosis; Tumor Suppressor Proteins

2023
Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma.
    Nature communications, 2023, 07-10, Volume: 14, Issue:1

    Topics: ErbB Receptors; Glioblastoma; Humans; Lysine; Methylation; NFATC Transcription Factors; Temozolomide; TNF Receptor-Associated Factor 6; Transcription Factors

2023
MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients.
    Journal of the neurological sciences, 2023, 09-15, Volume: 452

    Topics: Adult; Brain Neoplasms; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Mucins; Mutation; Prognosis; Retrospective Studies

2023
Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; B7-H1 Antigen; Glioblastoma; GTP-Binding Proteins; Humans; Methylation; Methyltransferases; Nuclear Proteins; Programmed Cell Death 1 Receptor; RNA; RNA-Binding Proteins; Tumor Microenvironment

2023
MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 11-01, Volume: 29, Issue:21

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Methylation; Prognosis; Tumor Suppressor Proteins

2023
MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value.
    Acta neuropathologica communications, 2023, 08-28, Volume: 11, Issue:1

    Topics: DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Isocitrate Dehydrogenase; Methylation; Prognosis; Prospective Studies; Retrospective Studies; Temozolomide; Tumor Suppressor Proteins

2023
MGMT promoter methylation status prediction using MRI scans? An extensive experimental evaluation of deep learning models.
    Medical image analysis, 2023, Volume: 90

    Topics: Aged; Brain Neoplasms; Deep Learning; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Magnetic Resonance Imaging; Methylation; Reproducibility of Results; Tumor Suppressor Proteins

2023
LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation.
    Nature communications, 2023, 11-18, Volume: 14, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Methylation; Neoplastic Stem Cells; Ribonucleoproteins, Small Nucleolar; RNA, Long Noncoding

2023
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival.
    British journal of cancer, 2019, Volume: 121, Issue:7

    Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Cell Line, Tumor; Drug Administration Schedule; Drug Resistance, Neoplasm; Glioblastoma; High-Throughput Nucleotide Sequencing; Humans; Kaplan-Meier Estimate; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Temozolomide; Transcription Factor RelA

2019
Paradoxical epigenetic regulation of XAF1 mediates plasticity towards adaptive resistance evolution in MGMT-methylated glioblastoma.
    Scientific reports, 2019, Oct-01, Volume: 9, Issue:1

    Topics: Adaptation, Physiological; Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Cell Line, Tumor; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Epigenesis, Genetic; Evolution, Molecular; Glioblastoma; Humans; Methylation; Temozolomide; Tumor Suppressor Proteins

2019
Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities.
    Acta neuropathologica communications, 2019, 10-28, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cerebellar Neoplasms; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p16; ErbB Receptors; Female; Glioblastoma; Humans; Infant; Infant, Newborn; Infratentorial Neoplasms; Male; Methylation; Middle Aged; Retrospective Studies; Telomerase; Young Adult

2019
The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells.
    Scientific reports, 2019, 11-04, Volume: 9, Issue:1

    Topics: Antibodies; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Glioblastoma; HEK293 Cells; Humans; Methylation; Neoplastic Stem Cells; Promoter Regions, Genetic; Protein Binding; Protein Stability; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-myc; Repressor Proteins; RNA Interference; RNA, Small Interfering; SOXB1 Transcription Factors

2019
Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years.
    Radiation oncology (London, England), 2019, Nov-12, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Methylation; Radiation Dose Hypofractionation; Retrospective Studies; Temozolomide; Treatment Outcome

2019
Survey of treatment recommendations for elderly patients with glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Health Care Surveys; Humans; Methylation; Oncologists; Physical Functional Performance; Radiotherapy Dosage; Spain; Temozolomide; Tumor Suppressor Proteins

2020
Does the expression of glial fibrillary acid protein (GFAP) stain in glioblastoma tissue have a prognostic impact on survival?
    Neuro-Chirurgie, 2020, Volume: 66, Issue:3

    Topics: Aged; Biomarkers; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Female; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Methylation; Middle Aged; Predictive Value of Tests; Prognosis; Survival Analysis; Tumor Suppressor Proteins

2020
SOX9-activated PXN-AS1 promotes the tumorigenesis of glioblastoma by EZH2-mediated methylation of DKK1.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:11

    Topics: Animals; Apoptosis; Base Sequence; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Humans; Intercellular Signaling Peptides and Proteins; Male; Methylation; Mice, Inbred BALB C; Promoter Regions, Genetic; RNA, Long Noncoding; SOX9 Transcription Factor; Wnt Signaling Pathway

2020
Molecular characteristics and clinical outcomes of elderly patients with IDH-wildtype glioblastomas: comparative study of older and younger cases in Kansai Network cohort.
    Brain tumor pathology, 2020, Volume: 37, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Brain Neoplasms; Cohort Studies; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Japan; Male; Methylation; Middle Aged; Prognosis; Survival Rate; Tumor Suppressor Proteins

2020
Prediction of MGMT Status for Glioblastoma Patients Using Radiomics Feature Extraction From
    International journal of radiation oncology, biology, physics, 2020, 12-01, Volume: 108, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Brain Neoplasms; Dihydroxyphenylalanine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Machine Learning; Male; Methylation; Middle Aged; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Tomography, X-Ray Computed; Tumor Suppressor Proteins; Young Adult

2020
The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status.
    Cell death & disease, 2020, 08-21, Volume: 11, Issue:8

    Topics: Adult; Brain Neoplasms; Chitinase-3-Like Protein 1; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Glioblastoma; Humans; Male; Methylation; Middle Aged; Neoplasm Recurrence, Local; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2020
Methylation associated miR-1246 contributes to poor prognosis in gliomas treated with temozolomide.
    Clinical neurology and neurosurgery, 2021, Volume: 200

    Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; MicroRNAs; Prognosis; Temozolomide

2021
Radiology in the lead: towards radiological profiling for precision medicine in glioblastoma patients? Editorial comment on Glioblastoma patients with a moderate vascular profile benefit the most from MGMT methylation.
    European radiology, 2021, Volume: 31, Issue:3

    Topics: Biomarkers, Tumor; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Methylation; Precision Medicine; Prognosis; Radiology; Tumor Suppressor Proteins

2021
Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification.
    Neuro-oncology, 2021, 07-01, Volume: 23, Issue:7

    Topics: Brain Neoplasms; DNA; DNA Copy Number Variations; DNA Methylation; Extracellular Vesicles; Glioblastoma; Humans; Methylation

2021
miRNA-mediated loss of m6A increases nascent translation in glioblastoma.
    PLoS genetics, 2021, Volume: 17, Issue:3

    Topics: 3' Untranslated Regions; Adenosine; Base Sequence; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; MicroRNAs; Microtubule-Associated Proteins; Protein Biosynthesis; RNA Interference; RNA, Messenger; Transcriptome; Tumor Cells, Cultured

2021
Keep it focused: PRMT6 drives the localization of RCC1 to chromosomes to facilitate mitosis, cell proliferation, and tumorigenesis.
    Molecular cell, 2021, 03-18, Volume: 81, Issue:6

    Topics: Carcinogenesis; Cell Cycle Proteins; Cell Proliferation; Chromosomes; Glioblastoma; Guanine Nucleotide Exchange Factors; Humans; Methylation; Mitosis; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Stem Cells

2021
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells.
    BMC cancer, 2021, May-03, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Celecoxib; Cell Cycle; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Etoricoxib; Female; Glioblastoma; Humans; Isoxazoles; Lactones; Male; Methylation; Middle Aged; Neoplasm Proteins; Pyrazoles; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Sulfones; Temozolomide; Tumor Suppressor Proteins; Wnt Signaling Pathway

2021
Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low-grade glioma.
    Molecular oncology, 2022, Volume: 16, Issue:2

    Topics: Animals; Brain Neoplasms; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Pericytes; Sequence Analysis, RNA; Single-Cell Analysis; Tumor Microenvironment; Tumor Suppressor Proteins; Up-Regulation

2022
Diagnostic and prognostic value of stem cell factor plasma level in glioblastoma multiforme patients.
    Cancer medicine, 2021, Volume: 10, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Case-Control Studies; Diagnosis, Differential; DNA Modification Methylases; DNA Repair Enzymes; Enzyme-Linked Immunosorbent Assay; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Methylation; Middle Aged; Mutation; Preoperative Period; Prognosis; Progression-Free Survival; ROC Curve; Stem Cell Factor; Tumor Burden; Tumor Suppressor Proteins

2021
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:2

    Topics: Adolescent; Brain Neoplasms; Glioblastoma; Humans; Methylation; Prognosis; Temozolomide; Valproic Acid; Vinblastine

2022
Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft.
    Investigational new drugs, 2017, Volume: 35, Issue:4

    Topics: Acetylation; Animals; Antineoplastic Agents; Astrocytes; Brain; Cell Line, Tumor; Cell Survival; DNA Damage; Doxorubicin; Epigenesis, Genetic; Glioblastoma; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Methylation; Mice, Nude; Myocardium; Prodrugs; Xenograft Model Antitumor Assays

2017
Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis.
    Cancer cell, 2017, 04-10, Volume: 31, Issue:4

    Topics: Carcinogenesis; Cell Transformation, Neoplastic; Glioblastoma; Humans; Methylation; RNA, Messenger

2017
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
    Cell reports, 2017, 05-30, Volume: 19, Issue:9

    Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Histones; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lipids; Methylation; Mice; Mice, SCID; Molecular Targeted Therapy; Mutation; NADP; Neoplastic Stem Cells; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Messenger

2017
Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy.
    International journal of radiation oncology, biology, physics, 2017, 07-15, Volume: 98, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Kaplan-Meier Estimate; Methylation; Multivariate Analysis; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Regression Analysis; Retrospective Studies; Temozolomide; Time Factors; Tumor Suppressor Proteins

2017
Further Investigation About Copy Number Variations and Methylation of AURKA, KIF4A, and NUSAP1 in Glioblastoma.
    World neurosurgery, 2018, Volume: 110

    Topics: Aurora Kinase A; Cell Line, Tumor; DNA Copy Number Variations; Glioblastoma; Methylation

2018
In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging.
    Clinical neuroradiology, 2019, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Brain Neoplasms; Cerebral Blood Volume; Chromosome Deletion; Chromosomes, Human, 1-3; Contrast Media; Cross-Sectional Studies; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Profiling; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Angiography; Methylation; Middle Aged; Mutation; Retrospective Studies; Tumor Suppressor Proteins; X-linked Nuclear Protein; Young Adult

2019
Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells.
    Cancer research, 2018, 05-15, Volume: 78, Issue:10

    Topics: Binding Sites; Brain Neoplasms; CCCTC-Binding Factor; Cell Dedifferentiation; Cell Line, Tumor; Cell Movement; Chromatin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glioblastoma; Histone Code; Humans; Methylation; Neoplastic Stem Cells; Protein Domains

2018
Histone H3.3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis.
    Journal of molecular biology, 2018, 05-25, Volume: 430, Issue:11

    Topics: Bone Neoplasms; Brain Neoplasms; Child; Epigenesis, Genetic; Giant Cell Tumor of Bone; Glioblastoma; HeLa Cells; Histones; Humans; Lysine; Methylation; Mutation

2018
Patterns of care and outcomes of chemoradiation versus radiation alone for MGMT promoter unmethylated glioblastoma.
    Clinical neurology and neurosurgery, 2018, Volume: 170

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Databases, Factual; DNA Modification Methylases; DNA Repair Enzymes; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Survival Rate; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins

2018
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration.
    Nucleic acids research, 2018, 07-27, Volume: 46, Issue:13

    Topics: Autoantigens; Cell Hypoxia; Cell Line; Cell Movement; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Golgi Matrix Proteins; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysine; Methylation; Response Elements; Transcription, Genetic

2018
PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma.
    Nature communications, 2018, 10-31, Volume: 9, Issue:1

    Topics: Arginine; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Oncogenes; Promoter Regions, Genetic; Protein-Arginine N-Methyltransferases; Transcription, Genetic

2018
A comprehensive analysis of factors related to carmustine/bevacizumab response in recurrent glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019, Volume: 21, Issue:10

    Topics: AC133 Antigen; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Carmustine; Chitinase-3-Like Protein 1; Colombia; DNA Modification Methylases; DNA Repair Enzymes; Drug Administration Schedule; Female; Genes, erbB-1; Genes, p53; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Methylation; Middle Aged; Mutation; Neoplasm Recurrence, Local; Progression-Free Survival; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Survival Analysis; Tumor Suppressor Proteins; Young Adult

2019
Correlation of radiological and immunochemical parameters with clinical outcome in patients with recurrent glioblastoma treated with Bevacizumab.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019, Volume: 21, Issue:10

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Cerebrovascular Circulation; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Amplification; Genes, erbB-1; Glioblastoma; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Methylation; Microvessels; Middle Aged; Mitotic Index; Neoplasm Recurrence, Local; Retrospective Studies; Tissue Array Analysis; Tumor Suppressor Proteins

2019
Posttreatment Effect of MGMT Methylation Level on Glioblastoma Survival.
    Journal of neuropathology and experimental neurology, 2019, 07-01, Volume: 78, Issue:7

    Topics: Aged; Brain Neoplasms; CpG Islands; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Epigenesis, Genetic; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Predictive Value of Tests; Prognosis; Progression-Free Survival; Survival Analysis; Tumor Suppressor Proteins

2019
Negative regulation of miR-1275 by H3K27me3 is critical for glial induction of glioblastoma cells.
    Molecular oncology, 2019, Volume: 13, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Methylation; Mice, Inbred BALB C; MicroRNAs; Neuroglia; Transcriptome

2019
Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling.
    Cancer discovery, 2019, Volume: 9, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Enhancer Elements, Genetic; Epigenesis, Genetic; ErbB Receptors; Fatty Acid Elongases; Fatty Acids, Unsaturated; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Methylation; Neoplastic Stem Cells; Signal Transduction; SOXB1 Transcription Factors; Up-Regulation

2019
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
    Science (New York, N.Y.), 2013, May-17, Volume: 340, Issue:6134

    Topics: Amino Acid Substitution; Animals; Brain Neoplasms; Child; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Glioblastoma; HEK293 Cells; Histones; Humans; Lysine; Methionine; Methylation; Mice; Mutation, Missense; Polycomb Repressive Complex 2; Transgenes

2013
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells.
    Cancer cell, 2013, Jun-10, Volume: 23, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Enhancer of Zeste Homolog 2 Protein; Gene Silencing; Glioblastoma; Humans; Methylation; Mice; Phosphorylation; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor; Transplantation, Heterologous; Tumor Cells, Cultured

2013
Assessment of genetic markers and glioblastoma stem-like cells in activation of dendritic cells.
    Human cell, 2013, Volume: 26, Issue:3

    Topics: Antigens, CD; Brain Neoplasms; Cell- and Tissue-Based Therapy; Coculture Techniques; Dendritic Cells; DNA Modification Methylases; DNA Repair Enzymes; Fetal Blood; Gene Expression Regulation, Neoplastic; Genetic Markers; Glioblastoma; Humans; Methylation; Neoplastic Stem Cells; Prognosis; PTEN Phosphohydrolase; Tumor Cells, Cultured; Tumor Suppressor Proteins

2013
Methylation by EZH2 activates STAT3 in glioblastoma.
    Cancer discovery, 2013, Volume: 3, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Neoplastic Stem Cells; Polycomb Repressive Complex 2; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2013
Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.
    Neuromolecular medicine, 2014, Volume: 16, Issue:1

    Topics: Apoptosis; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Enzyme Induction; Glioblastoma; Histone-Lysine N-Methyltransferase; Humans; Lysine; Methylation; Methyltransferases; Neoplasm Grading; Neoplasm Proteins; Protein Methyltransferases; Protein Processing, Post-Translational; Repressor Proteins; RNA Interference; RNA, Small Interfering; Tumor Stem Cell Assay; Up-Regulation

2014
Statistical and practical considerations for clinical evaluation of predictive biomarkers.
    Journal of the National Cancer Institute, 2013, Nov-20, Volume: 105, Issue:22

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Gefitinib; Glioblastoma; Humans; Indazoles; Interleukin-6; Kidney Neoplasms; Lung Neoplasms; Methylation; Molecular Targeted Therapy; Mutation; Neoplasms; Precision Medicine; Predictive Value of Tests; Pyrimidines; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Sample Size; Sulfonamides; Temozolomide; Tumor Suppressor Proteins

2013
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
    Cancer cell, 2013, Nov-11, Volume: 24, Issue:5

    Topics: Brain Neoplasms; Brain Stem Neoplasms; Cell Line, Tumor; Child; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Dominant; Glioblastoma; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Molecular Sequence Data; Mutation, Missense; Neoplasm Proteins; Polycomb Repressive Complex 2; Protein Binding; Protein Processing, Post-Translational; Transcription Factors; Transcription, Genetic

2013
Treatment of newly diagnosed malignant glioma in the elderly people: new trials that impact therapy.
    International journal of clinical practice, 2013, Volume: 67, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine; Glioblastoma; Guanosine; Humans; Methylation; Middle Aged; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Survival Rate; Temozolomide

2013
Double-labelling immunohistochemistry for MGMT and a "cocktail" of non-tumourous elements is a reliable, quick and easy technique for inferring methylation status in glioblastomas and other primary brain tumours.
    Acta neuropathologica communications, 2013, Jun-10, Volume: 1

    Topics: Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; False Negative Reactions; False Positive Reactions; Glioblastoma; Humans; Immunohistochemistry; Leukocyte Common Antigens; Methylation; Oligodendroglioma; Photomicrography; Retrospective Studies; Sensitivity and Specificity; Tumor Suppressor Proteins

2013
Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma and HCT-116 colon cancer cells.
    Molecules (Basel, Switzerland), 2014, Jan-20, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Biphenyl Compounds; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Glioblastoma; HCT116 Cells; Humans; Inhibitory Concentration 50; Leukemia; Lignans; Methylation; Microwaves

2014
Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells.
    BMB reports, 2014, Volume: 47, Issue:10

    Topics: Arsenites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Glioblastoma; Histones; Humans; Lysine; Methylation; Signal Transduction; Tumor Suppressor Protein p53

2014
Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.
    Stereotactic and functional neurosurgery, 2014, Volume: 92, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Prospective Studies; Registries; Retrospective Studies; Stereotaxic Techniques; Tumor Suppressor Proteins

2014
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
    Cell reports, 2014, Oct-09, Volume: 9, Issue:1

    Topics: 5-Methylcytosine; Acetylation; Brain Neoplasms; Carcinogenesis; Chromatin; Cytosine; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Histones; Humans; Methylation; Mixed Function Oxygenases; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins; Repressor Proteins; Transcription Factors; Transcription, Genetic

2014
Emerging role of linker histone variant H1x as a biomarker with prognostic value in astrocytic gliomas. A multivariate analysis including trimethylation of H3K9 and H4K20.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cohort Studies; Female; Glioblastoma; Histones; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Neoplasm Grading; Prognosis; Young Adult

2015
LRIG1, human EGFR inhibitor, reverses multidrug resistance through modulation of ABCB1 and ABCG2.
    Brain research, 2015, Jun-22, Volume: 1611

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; ErbB Receptors; Glioblastoma; Humans; Membrane Glycoproteins; Methylation; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Messenger; Temozolomide; Tumor Suppressor Proteins; Up-Regulation

2015
The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
    Neuro-oncology, 2015, Volume: 17, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Genotype; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins

2015
[Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:5

    Topics: Alkylating Agents; Brain Neoplasms; Dacarbazine; Epilepsies, Partial; Excitatory Amino Acid Antagonists; Glioblastoma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Mutation; Nitriles; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Pyridones; Survival Analysis; Temozolomide

2015
Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.
    Scientific reports, 2015, Nov-13, Volume: 5

    Topics: Adaptor Proteins, Signal Transducing; Arginine; Blotting, Western; Cell Line, Tumor; Chromatin; Glioblastoma; HEK293 Cells; Histones; Humans; Methylation; Microscopy, Confocal; Peptide Fragments; Protein Binding; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-myc; RNA Interference

2015
Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis.
    Journal of neuropathology and experimental neurology, 2016, Volume: 75, Issue:4

    Topics: Adult; Autoantigens; Brain Neoplasms; Cell Transformation, Neoplastic; Cluster Analysis; DNA Copy Number Variations; DNA Mutational Analysis; Genome, Human; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Neoplasms, Neuroepithelial; Proteasome Endopeptidase Complex

2016
Homeobox genes gain trimethylation of histone H3 lysine 4 in glioblastoma tissue.
    Bioscience reports, 2016, Volume: 36, Issue:3

    Topics: Brain Neoplasms; Cadherins; Chromatin Immunoprecipitation; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Homeobox; Glioblastoma; Histones; Humans; Lysine; Methylation; Middle Aged; Promoter Regions, Genetic

2016
MINA controls proliferation and tumorigenesis of glioblastoma by epigenetically regulating cyclins and CDKs via H3K9me3 demethylation.
    Oncogene, 2017, 01-19, Volume: 36, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Cyclins; Dioxygenases; Disease Progression; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Demethylases; Histones; Humans; Methylation; Mice; Neoplasm Transplantation; Nuclear Proteins; Prognosis; Survival Analysis

2017
The survival significance of a measurable enhancing lesion after completing standard treatment for newly diagnosed glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Retrospective Studies; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; Young Adult

2016
Frontal glioblastoma multiforme may be biologically distinct from non-frontal and multilobar tumors.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 34

    Topics: Adult; Aged; Brain Neoplasms; Female; Frontal Lobe; Glioblastoma; Humans; Isocitrate Dehydrogenase; Ki-67 Antigen; Male; Methylation; Middle Aged; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Retrospective Studies

2016
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
    Cell stem cell, 2017, 02-02, Volume: 20, Issue:2

    Topics: Acetylation; Base Sequence; Biomarkers, Tumor; Brain; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatin Assembly and Disassembly; Drug Resistance, Neoplasm; Enhancer Elements, Genetic; Glioblastoma; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Neoplastic Stem Cells; Nuclear Proteins; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Receptors, Notch; Signal Transduction; Transcription, Genetic

2017
LAPTM4B-35 is a novel prognostic factor for glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: Adult; Brain Neoplasms; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Ki-67 Antigen; Male; Membrane Proteins; Methylation; Middle Aged; Multivariate Analysis; Neovascularization, Pathologic; Oncogene Protein v-akt; Retrospective Studies; Tumor Suppressor Proteins

2017
Comparative analyses identify molecular signature of MRI-classified SVZ-associated glioblastoma.
    Cell cycle (Georgetown, Tex.), 2017, Apr-18, Volume: 16, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Isocitrate Dehydrogenase; Lateral Ventricles; Lysine; Magnetic Resonance Imaging; Methylation; Mutation; Neoplastic Stem Cells; Neural Stem Cells; Sequence Analysis, RNA

2017
m
    Cell reports, 2017, 03-14, Volume: 18, Issue:11

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Base Sequence; Brain Neoplasms; Carcinogenesis; Cell Differentiation; Cell Proliferation; Cell Self Renewal; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Meclofenamic Acid; Methylation; Methyltransferases; Mice; Neoplastic Stem Cells; RNA; RNA, Messenger

2017
Accelerated hypofractionated intensity-modulated radiotherapy with concurrent and adjuvant temozolomide for patients with glioblastoma multiforme: a safety and efficacy analysis.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Glioblastoma; Humans; Male; Methylation; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Radiotherapy, Intensity-Modulated; Retrospective Studies; Temozolomide; Treatment Outcome; Tumor Burden

2009
Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.
    Carcinogenesis, 2009, Volume: 30, Issue:2

    Topics: Animals; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chemotaxis; Decitabine; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, Formyl Peptide; Transplantation, Heterologous; Tumor Suppressor Protein p53

2009
High incidence of MGMT promoter methylation in primary glioblastomas without correlation with TP53 gene mutations.
    Cancer genetics and cytogenetics, 2009, Jan-15, Volume: 188, Issue:2

    Topics: Adult; Aged; Female; Gene Silencing; Genes, p53; Glioblastoma; Humans; Incidence; Male; Methylation; Middle Aged; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Tumor Suppressor Protein p53; Young Adult

2009
PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma.
    Cancer research, 2009, Apr-01, Volume: 69, Issue:7

    Topics: Animals; Carboxylic Ester Hydrolases; Cell Growth Processes; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Glioblastoma; HeLa Cells; Humans; Leucine; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Methylation; Mice; NIH 3T3 Cells; Protein Phosphatase 2; RNA, Small Interfering; Transfection

2009
Fotemustine and recurrent glioblastoma: possible new opportunities for an old drug.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioblastoma; Humans; Methylation; Neoplasm Recurrence, Local; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Organophosphorus Compounds; Promoter Regions, Genetic; Randomized Controlled Trials as Topic

2009
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Drug Administration Schedule; Genes, erbB-1; Genes, p53; Glioblastoma; Humans; Methylation; Mice; O(6)-Methylguanine-DNA Methyltransferase; PTEN Phosphohydrolase; Radiation-Sensitizing Agents; Random Allocation; Survival Analysis; Temozolomide; Xenograft Model Antitumor Assays

2009
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-01, Volume: 27, Issue:34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Methylation; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Survival Rate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Young Adult

2009
Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Celecoxib; Cyclooxygenase 2 Inhibitors; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Fluorine Radioisotopes; Follow-Up Studies; Glioblastoma; Humans; Male; Methylation; Middle Aged; Positron-Emission Tomography; Pyrazoles; Retrospective Studies; Sulfonamides; Temozolomide; Tumor Suppressor Proteins; Tyrosine

2010
Epithelioid glioblastoma changed to typical glioblastoma: the methylation status of MGMT promoter and 5-ALA fluorescence.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Aminolevulinic Acid; Biomarkers, Tumor; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Magnetic Resonance Angiography; Male; Methylation; Middle Aged; Neuronavigation; Polymerase Chain Reaction; Protoporphyrins; Spectrometry, Fluorescence; Tumor Suppressor Proteins

2011
Aberrant hypermethylation of non-promoter zygote arrest 1 (ZAR1) in human brain tumors.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:12

    Topics: Astrocytoma; Brain; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Egg Proteins; Glioblastoma; Glioma; Humans; Mass Spectrometry; Melanoma; Methylation; Nevus; Oligodendroglioma; Pituitary Neoplasms; Reference Values

2010
Quantitative digital assessment of MGMT immunohistochemical expression in glioblastoma tissue.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Gliosarcoma; Humans; Immunohistochemistry; Male; Methylation; Middle Aged; Tumor Suppressor Proteins

2011
Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme.
    Neurobiology of disease, 2011, Volume: 44, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Brain Neoplasms; Cell Line; Central Nervous System; CpG Islands; DNA Methylation; Gene Expression Regulation, Developmental; Glioblastoma; Hexokinase; Humans; Introns; Isoenzymes; Methylation; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sulfites

2011
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
    Journal of the National Cancer Institute, 2012, Jan-04, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Dacarbazine; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Gene Knockdown Techniques; Genetic Vectors; Glioblastoma; Humans; Immunoblotting; Immunohistochemistry; Methylation; Mice; Mice, Nude; Neoplastic Stem Cells; Oncolytic Virotherapy; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Simplexvirus; Temozolomide; Tumor Suppressor Proteins; Vero Cells; Virus Replication

2012
Volumetric and MGMT parameters in glioblastoma patients: survival analysis.
    BMC cancer, 2012, Jan-03, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Free Survival; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Profiling; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Prospective Studies; Survival Analysis; Temozolomide; Tumor Burden; Tumor Suppressor Proteins

2012
Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Postoperative Complications; Radiotherapy; Retrospective Studies; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins; Young Adult

2012
Case records of the Massachusetts General Hospital. Case 17-2012. A 54-year-old man with visual-field loss and a mass in the brain.
    The New England journal of medicine, 2012, May-31, Volume: 366, Issue:22

    Topics: Brain; Brain Neoplasms; Chemoradiotherapy; Diagnosis, Differential; Disease Progression; DNA Modification Methylases; DNA Repair Enzymes; Fatal Outcome; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Methylation; Middle Aged; Neoplasms, Second Primary; Recurrence; Tumor Suppressor Proteins; Vision Disorders

2012
Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Aug-01, Volume: 18, Issue:15

    Topics: Acetylation; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Kaplan-Meier Estimate; Methylation; Mice; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Tumor Suppressor Proteins; Up-Regulation; Vorinostat; Xenograft Model Antitumor Assays

2012
Distinct methylation profiles of glioma subtypes.
    International journal of cancer, 2003, Aug-10, Volume: 106, Issue:1

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; CpG Islands; Female; Glioblastoma; Glioma; Humans; Infant; Male; Methylation; Middle Aged; Oligodendroglioma; Prognosis; Sulfites

2003
PTEN methylation and expression in glioblastomas.
    Acta neuropathologica, 2003, Volume: 106, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Chromosomes, Human, Pair 10; DNA Mutational Analysis; Female; Glioblastoma; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Methylation; Middle Aged; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Promoter Regions, Genetic; PTEN Phosphohydrolase; Tumor Suppressor Proteins

2003
Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Astrocytes; Cell Line, Transformed; Cell Line, Tumor; Checkpoint Kinase 2; Dacarbazine; Enzyme Activation; G2 Phase; Glioblastoma; Humans; Methylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Temozolomide

2005
Phenytoin may increase the efficacy of temozolomide by methylating DNA-repair enzyme, O6-methylguanine-DNA methyltransferase in patients with glioblastoma.
    Medical hypotheses, 2005, Volume: 65, Issue:4

    Topics: Dacarbazine; DNA Repair; Glioblastoma; Humans; Methylation; O(6)-Methylguanine-DNA Methyltransferase; Phenytoin; Temozolomide

2005
Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas.
    Acta neuropathologica, 2005, Volume: 110, Issue:4

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Chromosomes, Human, Pair 22; Cohort Studies; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; In Situ Nick-End Labeling; Loss of Heterozygosity; Male; Methylation; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Temozolomide-mediated radiation enhancement in glioblastoma: a report on underlying mechanisms.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: Animals; Apoptosis; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models, Animal; DNA Damage; Glioblastoma; Guanine; Humans; Methylation; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Structure-Activity Relationship; Temozolomide; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2006
MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; DNA Modification Methylases; DNA Repair Enzymes; Drug Administration Schedule; Female; Glioblastoma; Humans; In Vitro Techniques; Methylation; Middle Aged; Prognosis; Retrospective Studies; Statistics, Nonparametric; Survival Analysis; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2007
A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Female; Fixatives; Formaldehyde; Gene Silencing; Glioblastoma; Humans; Male; Methylation; Middle Aged; Oligodendroglioma; Paraffin Embedding; Promoter Regions, Genetic; Reproducibility of Results; Tumor Suppressor Proteins

2007
Differential DNA methylation of the chorionic gonadotropin beta-subunit multigene family.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:10

    Topics: Base Sequence; Cell Line, Transformed; Choriocarcinoma; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Female; Gene Expression; Glioblastoma; Humans; Luteinizing Hormone; Methylation; Molecular Sequence Data; Multigene Family; Peptide Fragments; Placenta; Restriction Mapping; RNA, Messenger; Simian virus 40; Tumor Cells, Cultured

1993
[Characterization of chromosomal rearrangements by in situ hybridization in glioblastoma].
    Bulletin du cancer, 1994, Volume: 81, Issue:5

    Topics: Azacitidine; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; DNA, Neoplasm; DNA, Satellite; Glioblastoma; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Methylation; Middle Aged; Tumor Cells, Cultured

1994
Development and reversion of methionine dependence in a human glioma cell line: relation to homocysteine remethylation and cobalamin status.
    Cancer research, 1994, Sep-15, Volume: 54, Issue:18

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Brain Neoplasms; Female; Folic Acid; Glioblastoma; Homocysteine; Humans; Methionine; Methylation; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12

1994
DNA hypermethylation is associated with 17p allelic loss in neural tumors.
    Cancer research, 1993, Jun-15, Volume: 53, Issue:12

    Topics: Alleles; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 17; DNA, Neoplasm; Glioblastoma; Humans; Methylation; Neuroblastoma

1993
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Astrocytoma; Azacitidine; Base Sequence; Brain Chemistry; Brain Neoplasms; Carrier Proteins; Chromatin; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1996
Cellular uptake properties of a 2'-amino/2'-O-methyl-modified chimeric hammerhead ribozyme targeted to the epidermal growth factor receptor mRNA.
    Antisense & nucleic acid drug development, 1997, Volume: 7, Issue:4

    Topics: Base Sequence; Binding, Competitive; Biological Transport; Conserved Sequence; Dextran Sulfate; DNA; Endocytosis; Endosomes; ErbB Receptors; Glioblastoma; Heparin; Humans; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides, Antisense; Phosphorus Radioisotopes; RNA, Catalytic; RNA, Messenger; Spermidine; Subcellular Fractions; Thionucleotides; Tumor Cells, Cultured

1997
Transfer RNA and transfer RNA methylase in human brain tumors.
    Cancer research, 1971, Volume: 31, Issue:5

    Topics: Astrocytoma; Brain Chemistry; Brain Neoplasms; Glioblastoma; Humans; Meningioma; Methylation; Methyltransferases; Nucleosides; Oligodendroglioma; RNA, Transfer; Transferases

1971