Page last updated: 2024-08-18

isomethyleugenol and Amyotrophic Lateral Sclerosis

isomethyleugenol has been researched along with Amyotrophic Lateral Sclerosis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's13 (68.42)24.3611
2020's6 (31.58)2.80

Authors

AuthorsStudies
Bordoni, M; Carelli, S; Carra, S; Cereda, C; Crippa, V; Diamanti, L; Gagliardi, S; Garofalo, M; Jacchetti, E; Pandini, C; Pansarasa, O; Poletti, A; Raimondi, MT; Sproviero, D1
Adams, DA; Martin, LJ; Niedzwiecki, MV; Wong, M1
Barmada, SJ; Bekier, M; Gomez, N; Hsieh, C; Li, X; McMillan, M; Miguez, R; Tank, EMH1
Boeynaems, S; Clargo, A; Gitler, AD; Gittings, LM; Isaacs, AM; Lashley, T; Lightwood, D; Mann, DMA; Nakayama, L; Topia, S; Troakes, C1
Basavarajappa, BS; Subbanna, S1
Amaya, J; Burke, KA; Chabata, CV; Conicella, AE; Dignon, GL; Fawzi, NL; Mittal, J; Ryan, VH; Silva, R; Zerze, GH1
Barry, FA; Bondy-Chorney, E; Chitiprolu, M; Côté, J; Couture, JF; Gibbings, D; Jagow, C; Keith, J; Lavallée-Adam, M; Palidwor, G; Paris, G; Robertson, J; Rogaeva, E; Savard, A; Tremblay, V; Woulfe, J; Zinman, L1
Cornella, N; Gasperini, L; Macchi, P; Peroni, D; Potrich, V; Quattrone, A; Rossi, A; Zuccotti, P1
Aggarwal, T; Casci, I; Fackelmayer, FO; Lanson, NA; Maltare, A; Milioto, C; Monaghan, J; Pandey, UB; Pennuto, M; Scaramuzzino, C1
Bailey, TL; O'Connor, TR; Richard, S; Thandapani, P1
Bame, M; Brusilow, WS; Grier, RE; Needleman, R1
Davies, KE; Finelli, MJ; Liu, KX; Oliver, PL; Wu, Y1
Fujii, S; Kitajo, K; Takanashi, K; Yamaguchi, A1
Boeynaems, S; Bogaert, E; Callaerts, P; Cruts, M; Cuijt, I; De Baets, G; Gijselinck, I; Gitler, AD; Jovičić, A; Michiels, E; Robberecht, W; Rousseau, F; Scheveneels, W; Schymkowitz, J; Sieben, A; Steyaert, J; Van Broeckhoven, C; Van Damme, P; Van Den Bosch, L; Verstrepen, KJ1
Abou-Ajram, C; Ansorge, O; Arzberger, T; Bourgeois, B; Dormann, D; Edbauer, D; Funk, E; Göbl, C; Haass, C; Hartmann, H; Jutzi, D; Kremmer, E; Mackenzie, IR; Madl, T; Neumann, M; Reber, S; Resch, M; Ruepp, MD; Suárez-Calvet, M1
Boulanger, MC; Durham, HD; Richard, S; Tibshirani, M; Tradewell, ML; Yu, Z1
Abou-Ajram, C; Ansorge, O; Bentmann, E; Dormann, D; Haass, C; Kremmer, E; Mackenzie, IR; Madl, T; Neumann, M; Tahirovic, S; Valori, CF1
Blanchette, M; Cloutier, P; Coulombe, B; Faubert, D; Lavallée-Adam, M1

Reviews

3 review(s) available for isomethyleugenol and Amyotrophic Lateral Sclerosis

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Histone Methylation Regulation in Neurodegenerative Disorders.
    International journal of molecular sciences, 2021, Apr-28, Volume: 22, Issue:9

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Epigenesis, Genetic; Histone Code; Histones; Humans; Huntington Disease; Methylation; Neurodegenerative Diseases; Parkinson Disease; Protein Processing, Post-Translational; Substance-Related Disorders

2021
Defining the RGG/RG motif.
    Molecular cell, 2013, Jun-06, Volume: 50, Issue:5

    Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Apoptosis; Arginine; DNA Damage; Fragile X Syndrome; Humans; Methylation; Molecular Sequence Data; Neoplasms; Neuromuscular Diseases; Protein Biosynthesis; Protein Interaction Domains and Motifs; Proteins

2013

Trials

1 trial(s) available for isomethyleugenol and Amyotrophic Lateral Sclerosis

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023

Other Studies

16 other study(ies) available for isomethyleugenol and Amyotrophic Lateral Sclerosis

ArticleYear
RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1.
    Cells, 2022, 01-15, Volume: 11, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Case-Control Studies; Cell Nucleus; DNA Damage; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Histones; HSP70 Heat-Shock Proteins; Humans; Leukocytes, Mononuclear; Methylation; Principal Component Analysis; RNA; Superoxide Dismutase-1

2022
Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic.
    Cells, 2022, 10-31, Volume: 11, Issue:21

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; DNA; DNA Methylation; Humans; Methylation; Methyltransferases; Mice; Mice, Transgenic; Muscle, Skeletal; RNA; RNA Processing, Post-Transcriptional; Superoxide Dismutase; Superoxide Dismutase-1

2022
RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia.
    Molecular cell, 2023, Jan-19, Volume: 83, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Humans; Methylation; Neurons; RNA

2023
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity.
    Acta neuropathologica, 2020, Volume: 139, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Arginine; C9orf72 Protein; DNA Repeat Expansion; Frontotemporal Lobar Degeneration; Humans; Methylation

2020
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.
    Molecular cell, 2018, 02-01, Volume: 69, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Arginine; Frontotemporal Dementia; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Inclusion Bodies; Magnetic Resonance Imaging; Methylation; Mutation; Neurons; Protein Processing, Post-Translational

2018
A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.
    Nature communications, 2018, 07-18, Volume: 9, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Autophagy; C9orf72 Protein; Cell Line, Tumor; Cytoplasmic Granules; Embryo, Mammalian; HeLa Cells; Humans; Methylation; Mice; Mice, Knockout; Motor Neurons; Primary Cell Culture; Protein-Arginine N-Methyltransferases; RNA-Binding Protein FUS; Sequestosome-1 Protein; Stress, Physiological; Survival of Motor Neuron 1 Protein

2018
The hnRNP RALY regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization.
    Molecular biology of the cell, 2018, 12-15, Volume: 29, Issue:26

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Line, Tumor; Embryo, Mammalian; Gene Expression Regulation; HeLa Cells; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Mice; Motor Neurons; Mutation; Nuclear Localization Signals; Primary Cell Culture; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Spinal Cord

2018
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cytosol; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Inclusion Bodies; Membrane Proteins; Methylation; Methyltransferases; Mutant Proteins; Mutation; Protein Binding; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; Subcellular Fractions

2013
Amino acids as biomarkers in the SOD1(G93A) mouse model of ALS.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:1

    Topics: Age Factors; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Female; Glutamate-Ammonia Ligase; Humans; Longevity; Male; Metabolome; Methionine Sulfoximine; Methylation; Mice; Mice, Transgenic; Mutation; Sex Factors; Superoxide Dismutase; Superoxide Dismutase-1

2014
Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
    Human molecular genetics, 2015, Jun-15, Volume: 24, Issue:12

    Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Autophagy; Cytoplasm; DNA-Binding Proteins; Humans; Methylation; Mice; Mitochondrial Proteins; Mutation; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Aggregation, Pathological; Protein Binding; Protein Interaction Domains and Motifs; Protein Isoforms; Proteins; Proteolysis; RNA Splicing; RNA-Binding Protein FUS; Transcription, Genetic

2015
Treatment with a Global Methyltransferase Inhibitor Induces the Intranuclear Aggregation of ALS-Linked FUS Mutant In Vitro.
    Neurochemical research, 2016, Volume: 41, Issue:4

    Topics: Adenosine; Amyotrophic Lateral Sclerosis; Cell Line, Tumor; Cell Nucleus; HEK293 Cells; Humans; Methylation; Methyltransferases; Mutation; Protein Aggregates; RNA-Binding Protein FUS; Subcellular Fractions; Time Factors

2016
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
    Scientific reports, 2016, Feb-12, Volume: 6

    Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Nucleus; Dipeptides; Disease Models, Animal; Drosophila melanogaster; Eye; Frontotemporal Dementia; Genes, Insect; Genetic Testing; HeLa Cells; Humans; Methylation; Repetitive Sequences, Amino Acid; RNA Interference

2016
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
    Acta neuropathologica, 2016, Volume: 131, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies; Arginine; beta Karyopherins; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Embryonic Stem Cells; Enzyme Inhibitors; Female; Frontotemporal Lobar Degeneration; Humans; Inclusion Bodies; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Binding; Protein-Arginine N-Methyltransferases; Rats; RNA-Binding Protein FUS

2016
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations.
    Human molecular genetics, 2012, Jan-01, Volume: 21, Issue:1

    Topics: Amino Acid Motifs; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Line; Cell Nucleus; Cells, Cultured; Cytoplasm; Humans; Methylation; Mice; Motor Neurons; Mutation; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS

2012
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
    The EMBO journal, 2012, Nov-14, Volume: 31, Issue:22

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Arginine; Cell Nucleus; Frontotemporal Lobar Degeneration; Gene Silencing; HeLa Cells; Humans; Karyopherins; Methylation; Molecular Sequence Data; Nuclear Localization Signals; Proline; Protein Binding; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; Signal Transduction; Tyrosine

2012
A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
    PLoS genetics, 2013, Volume: 9, Issue:1

    Topics: Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Genome, Human; HEK293 Cells; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Mass Spectrometry; Methylation; Methyltransferases; Molecular Chaperones; Molecular Sequence Data; Mutation; Myositis, Inclusion Body; Osteitis Deformans; Phylogeny; Protein Processing, Post-Translational

2013