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isomethyleugenol and Akinetic-Rigid Variant of Huntington Disease

isomethyleugenol has been researched along with Akinetic-Rigid Variant of Huntington Disease in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's8 (23.53)18.2507
2000's5 (14.71)29.6817
2010's12 (35.29)24.3611
2020's4 (11.76)2.80

Authors

AuthorsStudies
Chighladze, E; Cole, RN; Faragó, A; Jiang, M; Jin, J; Kamath, SV; O'Meally, RN; Ratovitski, T; Rauniyar, P; Ross, CA; Shevelkin, AV1
Gordevičius, J; Graham, SF; Green, BD; Kerševičiūte, I; Khalid, A; Koladiya, PR; Macias, S; Mann, D; Pan, X; Radhakrishna, U; Robinson, AC; Saiyed, N; Vishweswaraiah, S; Yilmaz, A1
Anderson, EN; Basso, M; Caricasole, A; Grant, RA; Hernández, IH; Lucas, JJ; Migazzi, A; Pandey, UB; Pennuto, M; Ratovitski, T; Roccuzzo, M; Ross, CA; Saudou, F; Scaramuzzino, C; Tosatto, L; Tripathy, D; Virlogeux, A; Zuccato, C1
Basavarajappa, BS; Subbanna, S1
Bassi, S; Biagioli, M; Di Leva, F; Monziani, A; Tripathi, T1
Hu, W; Lin, X; Zhang, H; Zhao, N1
Bodai, L; Faragó, A; Marsh, JL; Song, W; Zsindely, N1
Monti, B; Peña-Altamira, LE; Polazzi, E1
Bates, GP; Bodai, L; Finkbeiner, S; Fraenkel, E; Gipson, TA; Housman, DE; Krainc, D; Kratter, IH; Labadorf, A; Lau, A; Marsh, JL; Ng, CW; Ross, CA; Sadri-Vakili, G; Song, W; Thompson, LM; Troncosco, J; Vashishtha, M; Vogel-Ciernia, A; Yildirim, F1
Hwang, YJ; Kowall, NW; Lee, J; Ryu, H1
Han, D; Hwang, YJ; Kim, KY; Kim, Y; Kowall, NW; Lee, J; Min, SJ; Ryu, H; Yang, L1
Fischhaber, PL; Guo, C; Tang, TS; Wang, F1
Di Stefano, L; Dietz, KN; Gusella, JF; Macdonald, ME; Maher, RC; Walker, JA; Zhu, H1
Derryberry, J; Hawk, AJ; Lanning, JD; Meredith, SC1
Cho, KS; Hong, YK; Hwang, YJ; Jeon, GS; Jung, MK; Kim, KY; Kowall, NW; Lee, J; Picketts, DJ; Ryu, H; Seong, KH1
Chan, JP; Festenstein, R; Goula, AV; Merienne, K; Stys, A; Trottier, Y1
Beal, MF; Browne, SE; Choi, DK; Ferrante, RJ; Gardian, G; Gregorio, J; Klivenyi, P; Kubilus, JK; Langley, B; Ratan, RR; Ryu, H1
Beal, MF; Browne, S; D'Mello, S; Ferrante, RJ; Hewett, S; Kristal, BS; Kubilus, JK; Langley, B; Lee, J; Lu, P; Ratan, RR; Rubinsztein, DC; Ryu, H; Smith, K; Stavrovskaya, IG; Sugars, KL1
Cormier, KA; Ferrante, RJ; Hagerty, SW; Lee, J; McAlpin, SE; Ryu, H; Smith, KM; Soh, BY1
Cormier, K; Del Signore, SJ; Ferrante, RJ; Goldstein, DR; Goodrich, S; Hagerty, SW; Luthi-Carter, R; Markey, AL; Matson, S; Ryu, H; Smith, K; Soh, BY; Stack, EC1
Cha, JH; Chawla, P; Kim, MO; Overland, RP; Sadri-Vakili, G; Xia, E1
Bates, G; Lehrach, H1
Harding, AE; Maher, ER; Morrison, PJ; Reik, W; Simpson, SA1
Carlock, L; Lorincz, M; Pandrangi, A; Vo, T; Wisniewski, D1
Conneally, PM; Cupples, LA; Farrer, LA; Kiely, DK; Myers, RH1
Conneally, PM; Farrer, LA; Frith, CD; Ridley, RM1
Collins, C; Hayden, MR; Kowbel, D; Riess, O; Weber, B1
Sapienza, C1
Laird, CD1
Ferluga, J1
Cox, DR; Myers, RM; Pritchard, CA1
Hayden, MR; Robbins, CA; Theilmann, JL1
Conneally, PM; Crow, TJ; Frith, CD; Ridley, RM1
Reik, W1

Reviews

6 review(s) available for isomethyleugenol and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Histone Methylation Regulation in Neurodegenerative Disorders.
    International journal of molecular sciences, 2021, Apr-28, Volume: 22, Issue:9

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Epigenesis, Genetic; Histone Code; Histones; Humans; Huntington Disease; Methylation; Neurodegenerative Diseases; Parkinson Disease; Protein Processing, Post-Translational; Substance-Related Disorders

2021
Epigenetics of Huntington's Disease.
    Advances in experimental medicine and biology, 2017, Volume: 978

    Topics: Acetylation; Animals; Cell Line; Chromatin Assembly and Disassembly; Clinical Trials as Topic; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Homeostasis; Humans; Huntingtin Protein; Huntington Disease; Methylation; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Polycomb-Group Proteins; Protein Processing, Post-Translational; RNA, Untranslated

2017
Histone post-translational modifications in Huntington's and Parkinson's diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Humans; Huntington Disease; Methylation; Molecular Targeted Therapy; Nerve Tissue Proteins; Neurons; Parkinson Disease; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination

2013
Nucleolar dysfunction in Huntington's disease.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:6

    Topics: Acetylation; Cell Nucleolus; Epigenesis, Genetic; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mutation; Nerve Tissue Proteins; Neurons; Pol1 Transcription Initiation Complex Proteins; Trinucleotide Repeat Expansion

2014
Trinucleotide repeat expansions and human genetic disease.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1994, Volume: 16, Issue:4

    Topics: Adult; Age of Onset; Base Sequence; Child; Embryonic and Fetal Development; Fragile X Syndrome; Genetic Diseases, Inborn; Humans; Huntington Disease; Infant, Newborn; Intellectual Disability; Male; Methylation; Middle Aged; Molecular Sequence Data; Muscular Atrophy, Spinal; Myotonic Dystrophy; Repetitive Sequences, Nucleic Acid; Spermatozoa; Spinocerebellar Degenerations

1994
Proposed genetic basis of Huntington's disease.
    Trends in genetics : TIG, 1990, Volume: 6, Issue:8

    Topics: Adolescent; Adult; Age Factors; Alleles; Animals; Child; Child, Preschool; Chromosomes, Human, Pair 4; Drosophila melanogaster; Epistasis, Genetic; Female; Gene Expression Regulation; Genes; Genes, Dominant; Genes, Regulator; Heterozygote; Humans; Huntington Disease; Male; Methylation; Middle Aged; Models, Genetic; Transcription Factors; X Chromosome

1990

Other Studies

28 other study(ies) available for isomethyleugenol and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity.
    Human molecular genetics, 2022, 05-19, Volume: 31, Issue:10

    Topics: Animals; Arginine; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Nuclear Proteins; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Solubility

2022
Integrative Analysis Unveils the Correlation of Aminoacyl-tRNA Biosynthesis Metabolites with the Methylation of the
    Genes, 2023, 09-02, Volume: 14, Issue:9

    Topics: Amino Acyl-tRNA Synthetases; Brain; Humans; Huntington Disease; Metabolome; Methylation; RNA, Transfer

2023
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
    Cell reports, 2021, 04-13, Volume: 35, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Axonal Transport; Brain-Derived Neurotrophic Factor; Cell Death; Disease Models, Animal; Drosophila melanogaster; Epigenesis, Genetic; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neuromuscular Junction; Neurons; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Transport Vesicles

2021
ATP Binding Cassette Subfamily A Member 2 (ABCA2) Expression and Methylation are Associated with Alzheimer's Disease.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Dec-10, Volume: 23

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; ATP-Binding Cassette Transporters; Cognitive Dysfunction; CpG Islands; Databases, Genetic; Epigenesis, Genetic; Genetic Predisposition to Disease; Humans; Huntington Disease; Methylation; RNA, Messenger; Tissue Array Analysis; Up-Regulation

2017
Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease.
    Human molecular genetics, 2018, 02-15, Volume: 27, Issue:4

    Topics: Animals; Animals, Genetically Modified; Chromatin; Chromatin Immunoprecipitation; Drosophila melanogaster; Female; Heterochromatin; Histone Demethylases; Histones; Huntington Disease; Male; Methylation; Polycomb-Group Proteins

2018
Targeting H3K4 trimethylation in Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-06, Volume: 110, Issue:32

    Topics: Animals; Animals, Genetically Modified; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Drosophila melanogaster; Female; Gene Expression Profiling; Histone Demethylases; Histones; Humans; Huntingtin Protein; Huntington Disease; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nerve Tissue Proteins; Neurons; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2013
ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription.
    Nucleic acids research, 2014, Volume: 42, Issue:3

    Topics: Animals; Cell Line; Cell Nucleolus; DNA, Ribosomal; Heterochromatin; Histone-Lysine N-Methyltransferase; Humans; Huntington Disease; Methylation; Mice; Mutation; Pol1 Transcription Initiation Complex Proteins; Transcription, Genetic

2014
Epigenetic modifications as novel therapeutic targets for Huntington's disease.
    Epigenomics, 2014, Volume: 6, Issue:3

    Topics: Acetylation; Animals; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Nerve Tissue Proteins; Ubiquitination

2014
The Drosophila Huntington's disease gene ortholog dhtt influences chromatin regulation during development.
    Human molecular genetics, 2015, Jan-15, Volume: 24, Issue:2

    Topics: Animals; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation, Developmental; Heterochromatin; Humans; Huntingtin Protein; Huntington Disease; Male; Methylation; Microtubule-Associated Proteins; Ovary; Wings, Animal

2015
Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation.
    Biochemistry, 2010, Aug-24, Volume: 49, Issue:33

    Topics: Humans; Huntington Disease; Methylation; Peptides; Protein Structure, Secondary; Surface Plasmon Resonance

2010
ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease.
    Cell death and differentiation, 2012, Volume: 19, Issue:7

    Topics: Animals; Base Sequence; CDX2 Transcription Factor; Cell Line; DNA Helicases; Drosophila; Drosophila Proteins; Heterochromatin; Histones; Homeodomain Proteins; Humans; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; X-linked Nuclear Protein

2012
Transcription elongation and tissue-specific somatic CAG instability.
    PLoS genetics, 2012, Volume: 8, Issue:11

    Topics: Animals; Chromatin; Corpus Striatum; Disease Models, Animal; DNA-Directed RNA Polymerases; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Organ Specificity; Transcription, Genetic; Trinucleotide Repeat Expansion

2012
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
    The Journal of biological chemistry, 2005, Jan-07, Volume: 280, Issue:1

    Topics: Acetylation; Animals; Brain; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Huntingtin Protein; Huntington Disease; Male; Methylation; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; Phenylbutyrates; Trinucleotide Repeat Expansion; Ubiquitin

2005
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Nov-17, Volume: 24, Issue:46

    Topics: Animals; Antibiotics, Antineoplastic; Brain; Cells, Cultured; Gene Silencing; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Lysine; Male; Methylation; Mice; Mice, Transgenic; Mitochondria, Liver; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Plicamycin; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, Glutamate; Transcription, Genetic

2004
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-12, Volume: 103, Issue:50

    Topics: Aged; Animals; Cystamine; Female; Gene Expression; Histone-Lysine N-Methyltransferase; Histones; Humans; Huntington Disease; Male; Methylation; Mice; Middle Aged; Phenotype; Plicamycin; Promoter Regions, Genetic; Protein Methyltransferases; Sp3 Transcription Factor; Survival Rate; Up-Regulation

2006
Modulation of nucleosome dynamics in Huntington's disease.
    Human molecular genetics, 2007, May-15, Volume: 16, Issue:10

    Topics: Acetylation; Animals; Brain; Chromomycins; Disease Models, Animal; Female; Histones; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Nuclear Proteins; Nucleosomes; Plicamycin; Transcription, Genetic

2007
Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Apr-09, Volume: 28, Issue:15

    Topics: Animals; Brain; Cells, Cultured; Histones; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Repressor Proteins; Transcription, Genetic; Ubiquitination

2008
Age at onset in Huntington's disease and methylation at D4S95.
    Journal of medical genetics, 1993, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Chromosomes, Human, Pair 4; DNA; Electrophoresis, Agar Gel; Female; Gene Expression Regulation; Humans; Huntington Disease; Male; Methylation; Middle Aged; Mutation; Paternal Age

1993
An estimate of the number of genes in the Huntington disease gene region and the identification of 13 transcripts in the 4p16.3 segment.
    Genomics, 1992, Volume: 13, Issue:4

    Topics: Blotting, Northern; Blotting, Southern; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 4; DNA; Electrophoresis, Gel, Pulsed-Field; Humans; Huntington Disease; Methylation; Restriction Mapping; Transcription, Genetic

1992
Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting.
    American journal of human genetics, 1992, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Age Factors; Birth Order; Child; DNA; Family Health; Female; Gene Expression Regulation; Humans; Huntington Disease; Least-Squares Analysis; Male; Maternal Age; Methylation; Middle Aged; Parents; Parity; Paternal Age; Regression Analysis; Sex Factors

1992
Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.
    Journal of medical genetics, 1991, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Age Factors; Alleles; Gene Expression; Genetic Variation; Humans; Huntington Disease; Methylation; Pedigree; Surveys and Questionnaires

1991
Identification of multiple CpG islands and associated conserved sequences in a candidate region for the Huntington disease gene.
    Genomics, 1991, Volume: 11, Issue:4

    Topics: Animals; Base Sequence; Biological Evolution; Chromosome Walking; Chromosomes, Human, Pair 4; Cloning, Molecular; Cosmids; Dinucleoside Phosphates; DNA; Electrophoresis, Gel, Pulsed-Field; Humans; Huntington Disease; Methylation; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Nucleic Acid

1991
Parental imprinting of genes.
    Scientific American, 1990, Volume: 263, Issue:4

    Topics: Animals; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; DNA; Female; Genetic Diseases, Inborn; Genetics; Humans; Huntington Disease; Male; Methylation; Mice; Ovum; Rhabdomyosarcoma; Sex Chromosomes; Spermatozoa

1990
Possible organ and age-related epigenetic factors in Huntington's disease and colorectal carcinoma.
    Medical hypotheses, 1989, Volume: 29, Issue:1

    Topics: Aging; Animals; Chromosome Deletion; Colorectal Neoplasms; Gene Expression Regulation; Genes, Switch; Humans; Huntington Disease; Methylation; Mutation

1989
Methylation at the Huntington disease-linked D4S95 locus.
    American journal of human genetics, 1989, Volume: 45, Issue:2

    Topics: Alleles; Cell Line; DNA; Genetic Linkage; Humans; Huntington Disease; Methylation; Plasmids

1989
Methylation at the D4S95 locus and predictive testing.
    American journal of human genetics, 1989, Volume: 45, Issue:3

    Topics: Genetic Linkage; Genetic Markers; Humans; Huntington Disease; Methylation; Predictive Value of Tests; Repetitive Sequences, Nucleic Acid

1989
Anticipation in Huntington's disease is inherited through the male line but may originate in the female.
    Journal of medical genetics, 1988, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Age Factors; Alleles; DNA; Epidemiologic Methods; Female; Humans; Huntington Disease; Male; Methylation; Sex Factors; United States

1988
Genomic imprinting: a possible mechanism for the parental origin effect in Huntington's chorea.
    Journal of medical genetics, 1988, Volume: 25, Issue:12

    Topics: Age Factors; Alleles; Animals; Gene Expression Regulation; Humans; Huntington Disease; Methylation; Mice; Sex Characteristics

1988