isomethyleugenol has been researched along with Aging in 269 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (34.94) | 18.7374 |
| 1990's | 53 (19.70) | 18.2507 |
| 2000's | 25 (9.29) | 29.6817 |
| 2010's | 70 (26.02) | 24.3611 |
| 2020's | 27 (10.04) | 2.80 |
| Authors | Studies |
|---|---|
| Baldensperger, T; Dau, T; Di Sanzo, S; Glomb, MA; Heller, R; Henning, C; Kirkpatrick, JM; Leheis, A; Marx, C; Ori, A; Parca, L; Rändler, TL; Spengler, K; Wang, ZQ | 1 |
| Bielak-Zmijewska, A; Dudkowska, M; Figiel, I; Gadecka, A; Krzystyniak, A; Mosieniak, G; Petrazzo, G; Sikora, E; Wesierska, M; Wlodarczyk, J | 1 |
| Chen, T; Ding, Z; Ge, W; Liu, J; Zhang, J; Zhao, Y | 1 |
| Kaner, RJ | 1 |
| An, Y; Li, Y; Pan, X; Ruan, G; Tian, C; Wei, W; Zhao, J; Zhu, X | 1 |
| Kresovich, JK; Sandler, DP; Taylor, JA | 1 |
| Bakhle, KM; Hagins, AC; Jauregui-Lozano, J; McGovern, SE; Weake, VM | 1 |
| Caratelli, S; Cenciarelli, C; Cesarini, V; Colopi, A; De Paolis, F; Dolci, S; Gallo, A; Guida, E; La Rosa, P; Sconocchia, G; Tassinari, V | 1 |
| Chang, VY; Cunniff, C; Flanagan, M; Gordevičius, J; Haghani, A; Horvath, S; Kucine, N; Lee, J; Lu, AT; Martinez, JA; Zhang, J | 1 |
| Chen, R; Du, HN; Li, YM; Liu, AH; Mei, YC; Wang, RX | 1 |
| Mienaltowski, MJ; Pechanec, MY | 1 |
| Alonso, AP; Cocuron, JC; Cooper, GL; Hoffman, CN; Huseby, CJ; Kuret, J; Thomas, SN; Yang, AJ | 1 |
| Anandh, S; Bochkis, IM; Kain, J; Manjegowda, MC; Price, AJ | 1 |
| Matsushita, K; Tamura, M; Ukita, M; Yamaguchi, T | 1 |
| Cai, SQ; Chang, SY; Chen, Z; Cheng, X; Gao, G; Hao, P; Jiang, L; Jiang, Q; Kang, XL; Lin, DY; Liu, XJ; Liu, ZY; Ye, SW; Yin, JA; Yin, SG; Yuan, J | 1 |
| Khair, L; Messina, LM; Tie, G; Tutto, A; Yan, J | 1 |
| Bao, XM; Deng, AC; Li, Q; Liang, XJ; Wang, M; Xiang, YH; Zhang, Y; Zhao, PP; Zhu, XB | 1 |
| Cakouros, D; Gronthos, S | 1 |
| Chen, Y; Deng, H; Liu, C; Ma, Y; Wang, Q; Yi, M | 1 |
| Bradley, BJ; Ely, JJ; Guevara, EE; Hopkins, WD; Lawler, RR; Sherwood, CC; Staes, N; White, CM | 1 |
| Juin, SK; Kulkarni, R; Majumder, S; Pushpakumar, S; Ren, L; Sen, U | 1 |
| Chen, Y; Deng, P; Guo, Y; Li, Q; Lin, W; Liu, W; Liu, Y; Ou, G; Qi, X; Wang, C; Wang, Y; Wu, Y; Yuan, Q; Zhang, S; Zheng, X; Zhou, L | 1 |
| Engdahl, C; Farman, HH; Gustafsson, KL; Henning, P; Lagerquist, MK; Lawenius, L; Lionikaite, V; Movérare-Skrtic, S; Nilsson, KH; Ohlsson, C | 1 |
| Allen, EG; Dai, Q; Duan, R; Guo, Z; He, C; Jin, P; Kang, Y; Li, Y; Pajdzik, K; Shafik, AM; Wu, H; Yao, B; Zhang, F | 1 |
| Huang, G; Huang, J; Ruan, Y; Song, S; Wu, S; Xiang, X; Ye, L | 1 |
| Bagryanova, LR; Brown, JL; Campana, MG; E Maldonado, J; Haghani, A; Horvath, S; Prado, NA; Raj, K; Robeck, TR; Schmitt, D; Yao, M; Zoller, JA | 1 |
| Chen, SH; Cui, WY; Lv, QL; Shen, XL; Tan, ZL; Wang, LC; Zhang, Z | 1 |
| Chu, K; Dai, ZH; Gu, JY; He, Y; Ji, YX; Jiang, ZX; Li, W; Li, ZY; Sun, NX; Wang, YN; Yang, F | 1 |
| Han, M; Li, G; Shi, C; Sun, L; Wu, X; Xu, T; Ye, Z; Zhao, S; Zhuang, Y | 1 |
| Brunet, A; Han, S; Hebestreit, K; Mair, WB; Schroeder, EA; Silva-García, CG | 1 |
| Jensen, ON; Kempf, SJ; Rogowska-Wrzesinska, A; Schwämmle, V; Tvardovskiy, A | 1 |
| Ding, C; Feng, S; Huang, Y; Liu, J; Shen, S; Wang, H; Xu, Z; Yuan, M; Zhou, L | 1 |
| Cant, JP; McKnight, LM; Shoveller, AK; Wood, KM | 1 |
| Berger, MS; Cardona, AE; Cardona, SM; Huang, SA; Lemmon, VP; Lin, CA; Rhodes, CT; Zunino, G | 1 |
| Borowczyk, K; Jakubowski, H; Suliburska, J | 1 |
| Antunes-Rodrigues, J; Greenwood, M; Greenwood, MP; Japundžić-Žigon, N; Mecawi, AS; Murphy, D; Paterson, A; Paton, JFR; Romanova, EV; Sarenac, O; Sweedler, JV | 1 |
| Cummings, JC; Davila, S; Fomin, M; Georgescu, C; Hafner, M; Kwon, SH; Makowsky, D; Mcdowell, CH; Min, KW; Thigpen, H; Wren, JD; Yoon, JH; Zealy, RW | 1 |
| Auwerx, J; Menzies, KJ; Zhang, H | 1 |
| Baric, RS; Dinnon, KH; Graham, RL; Gralinski, LE; Leist, SR; McAnarney, ET; Menachery, VD; Mitchell, HD; Waters, KM; Yount, BL | 1 |
| Bahous, RH; Bedell, BJ; Caudill, MA; Cosín-Tomás, M; Deng, L; Ho, MK; Kaliman, P; Leclerc, D; Malysheva, O; Pallàs, M; Rozen, R | 1 |
| Bonini, NM; Kennerdell, JR; Liu, N | 1 |
| Karen, C; Rajan, KE | 1 |
| Christensen, BC | 1 |
| Brand, M; Chaturvedi, CP; Gulyani, A; Kedia, N; Ketkar, AA; Krishnamoorthy, VK; Kumar, P; Kumar, SD; Lakshmanan, V; Mohanty, A; Palakodeti, D; Raja, SO; Rampalli, S; Rao, RA | 1 |
| Larrick, JW; Mendelsohn, AR | 2 |
| Andrade, G; Basso, CG; Cechinel, LR; de Meireles, LCF; de Souza Grefenhagen, ÁI; Galvão, F; Lovatel, GA; Nestler, EJ; Palazzo, RP; Siqueira, IR; Walker, DM | 1 |
| Dittrich, M; Flunkert, J; Haaf, T; Maierhofer, A; Martin, GM; Müller, T; Nanda, I; Oshima, J; Poot, M | 1 |
| Chang, SW; Kakigi, R; Machida, S; Naito, H; Sugiura, T; Tsuzuki, T; Yoshihara, T | 1 |
| Anton, PM; Barbezier, N; Chango, A; Coeffier, M; Delayre-Orthez, C; Ettreiki, C | 1 |
| Colonna, G; Costantini, S; Sharma, A | 1 |
| Cai, YN; Li, L; Li, YL; Lin, QL; Lu, L; Sun, FL; Wang, DH; Yang, CC; Zhang, L | 1 |
| Adams, PD; Aggarwala, V; Berger, SL; Cao, K; Capell, BC; Cruickshanks, HA; Donahue, G; Gregory, BD; McBryan, T; Nelson, DM; Otte, GL; Rai, TS; Shah, PP | 1 |
| Dowd, SE; Kellermayer, R; Mir, SA; Nagy-Szakal, D; Smith, CW; Szigeti, RG | 1 |
| Banerjee, R; Delaney, C; Garg, SK; Ghosh, A; Reddy, P; Toubai, T; Yung, R | 1 |
| Abe, M; Bonini, NM; Feltzin, V; Grigoriev, A; Hendriks, GJ; Naqvi, A; Zhu, Y | 1 |
| Baron, J; Chen, W; Cheung, CS; Lui, JC | 1 |
| Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C | 1 |
| Sen, N | 1 |
| Wallace, SS | 1 |
| Dang, W; McCauley, BS | 1 |
| Hiltunen, M; Kaarniranta, K; Kauppinen, A; Salminen, A | 1 |
| Alvarez-López, MJ; Castro-Freire, M; Cosín-Tomás, M; Cristòfol, R; Escorihuela, RM; Kaliman, P; Molina-Martínez, P; Pallàs, M; Párrizas, M; Sanfeliu, C | 1 |
| Benard, A; Böhringer, S; Goossens-Beumer, IJ; Kuppen, PJ; Liefers, GJ; Morreau, H; Putter, H; van de Velde, CJ; van Hoesel, AQ; Zeestraten, EC | 1 |
| Chisholm, NC; Dindot, S; Henderson, ML; Miranda, RC; Park, MJ; Selvamani, A; Sohrabji, F | 1 |
| Baccarelli, AA; Bind, MA; Byun, HM; Cantone, L; Colicino, E; Kloog, I; Lin, X; Mehta, A; Prada, D; Schwartz, J; Sparrow, D; Tarantini, L; Trevisi, L; Vokonas, P; Zanobetti, A; Zhong, J | 1 |
| Helfand, SL; Lee, SS; Ni, Z; Pu, M; Wang, M; Wang, X; Wood, JG; Yu, H | 1 |
| Horvath, S; Levine, AJ | 1 |
| Gogoshin, G; Jin, SG; Jung, M; Pfeifer, GP; Rodin, AS; Xiong, W; Zhang, X | 1 |
| Cifuentes-Gomez, T; Gonzalez-Salvador, I; Heiss, C; Kelm, M; Ottaviani, JI; Rodriguez-Mateos, A; Schroeter, H; Spencer, JP | 1 |
| Affinito, O; Belardo, C; Chiariotti, L; Cristino, L; De Novellis, V; Errico, F; Florio, E; Imperatore, R; Keller, S; Luongo, L; Maddaloni, G; Maione, S; Migliarini, S; Nuzzo, T; Pasqualetti, M; Pollegioni, L; Punzo, D; Sacchi, S; Sisalli, MJ; Usiello, A | 1 |
| Chen, H; Xiao, D; Zheng, X; Zheng, Y | 1 |
| Chovatiya, GL; Gupta, S; Khade, B; Ravi, V; Sarate, RM; Waghmare, SK | 1 |
| Asara, JM; Binari, R; Demontis, F; Parkhitko, AA; Perrimon, N; Zhang, N | 1 |
| Dankert, D; Demond, H; Eichenlaub-Ritter, U; Grümmer, R; Heiligentag, M; Horsthemke, B; Trapphoff, T | 1 |
| Ahmed, T; Baliyan, S; Balschun, D; Dotti, CG; Martin, MG; Martín-Segura, A; Palomer, E; Venero, C | 1 |
| Bendixen, C; Farajzadeh, L; Kristensen, KK; Larsen, K; Momeni, J | 1 |
| Carter, RE; Dasari, S; Esponda, RR; Johnson, ML; Konopka, AR; Lanza, IR; Manjunatha, S; Nair, KS; Robinson, MM | 1 |
| Blanc, RS; Richard, S | 1 |
| Goto, S; Ishigami, A; Kawakami, K; Nakamura, A; Takahashi, R | 1 |
| Fujita, H; Harada, K; Hiraoka, S; Horii, J; Kato, J; Kuwaki, K; Toyooka, S; Yamamoto, K | 1 |
| Andrews, LG; Love, WK; Mott, TE; Phipps, SM; Tollefsbol, TO | 1 |
| Fujita, H; Harada, K; Hiraoka, S; Horii, J; Kaji, E; Kato, J; Saito, S; Yamamoto, K | 1 |
| Fraser, T; Love, S; Tayler, H | 1 |
| Fenech, M | 1 |
| Gonzalo, S | 1 |
| Fabrizio, P; Galbani, A; Giaever, G; Hoon, S; Longo, VD; Nislow, C; Shamalnasab, M; Wei, M | 1 |
| Knab, B; Osiewacz, HD | 1 |
| Bhadhprasit, W; Kawasaki, Y; Nemoto, N; Sakuma, T | 1 |
| Arima, T; Maeda, T; Makino, N; Oyama, JI; Sasaki, M | 1 |
| Anderson, HC; Crist, JD; Gardner, BM; Li, Y; Lu, Q; Rodova, M; Wang, J; Woodbury, BG; Yost, JG; Zhong, XB | 1 |
| Altelaar, AF; Bakker, BM; de Graaf, EL; De Vos, D; Frederiks, F; Heck, AJ; Iachina, E; Krijgsveld, J; Oudgenoeg, G; Terweij, M; van Leeuwen, F; van Welsem, T; Verzijlbergen, KF | 1 |
| van Leeuwen, F; Vlaming, H | 1 |
| David, LL; Davies, MJ; Friedrich, MG; Hooi, MY; Jamie, JF; Lyons, B; Mizdrak, J; Truscott, RJ; Wilmarth, PA | 1 |
| Amstislavskiy, V; Ast, V; Avci, M; Bartholomae, CC; Bender, S; Benes, V; Betts, MJ; Brors, B; Cho, YJ; Cin, H; Clifford, SC; Coco, S; Collins, VP; Ebinger, M; Eils, J; Eils, R; Felsberg, J; Frühwald, MC; Graf, N; Hans, V; Hasselblatt, M; Herold-Mende, C; Hovestadt, V; Hutter, B; Hutter, S; Jabado, N; Jäger, N; Jones, DT; Kabbe, R; Kim, YJ; Kool, M; Korbel, JO; Korshunov, A; Koster, J; Kulozik, AE; Lasitschka, B; Lawerenz, C; Lehrach, H; Lichter, P; Maass, E; McCabe, MG; Meyerson, M; Milde, T; Monoranu, C; Northcott, PA; Pfaff, E; Pfister, SM; Pleier, S; Pomeroy, SL; Pugh, TJ; Raeder, B; Rausch, T; Reifenberger, G; Remke, M; Roggendorf, W; Rössler, J; Russell, RB; Rutkowski, S; Ryzhova, M; Scheurlen, W; Schmidt, M; Schuhmann, MU; Schüller, U; Shih, D; Sieber, L; Sturm, D; Stütz, AM; Sultan, M; Taylor, MD; Tonini, GP; Tzaridis, T; Unterberg, A; van Sluis, P; Volckmann, R; von Bueren, AO; von Deimling, A; von Kalle, C; Wang, Q; Warnatz, HJ; Weber, UD; Weischenfeldt, J; Wiemann, S; Williamson, D; Witt, H; Witt, O; Wittmann, A; Wolf, S; Yaspo, ML; Zapatka, M; Zichner, T | 1 |
| Alonso-Aperte, E; Partearroyo, T; Pérez-Miguelsanz, J; Úbeda, N; Valencia-Benítez, M; Varela-Moreiras, G | 1 |
| Liang, X; Ma, J; Schatten, H; Sun, Q | 1 |
| Ikegami, D; Kim, YJ; Niwa, T; Takeshima, H; Ushijima, T; Wakabayashi, M | 1 |
| Boyd-Kirkup, JD; Green, CD; Han, D; Han, JD; Han, Y; Khaitovich, P; Yan, Z | 1 |
| Iida, A; Iwagawa, T; Mochizuki, Y; Murakami, A; Usui, A; Watanabe, S; Wegner, M | 1 |
| Guan, DL; Liang, L; Zhang, M | 1 |
| Helliger, W; Koutzamani, E; Lindner, HH; Rundquist, I; Sarg, B | 1 |
| Lapko, VN; Smith, DL; Smith, JB | 2 |
| Mattson, MP; Shea, TB | 1 |
| Bakala, H; Bismuth, J; Borot-Laloi, C; Corman, B; Delaval, E; Friguet, B; Hamelin, M | 1 |
| OERIU, S; TANASE, I | 2 |
| Fukagawa, NK; Galbraith, RA | 1 |
| Kumar, RC; Thakur, MK | 1 |
| Baylin, SB; Chen, WY; Gu, W; Luo, J; Wang, DH; Yen, RC | 1 |
| Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I | 1 |
| Leslie, M | 1 |
| Ingenbleek, Y | 1 |
| Blair, ME; Emmert, JL; Fanatico, AC; Pillai, PB | 1 |
| Agrelo, R | 1 |
| Adam, SA; Andres, DA; Dechat, T; Goldman, RD; Rusinol, AE; Shimi, T; Sinensky, MS; Spielmann, HP | 1 |
| Azzi, S; Bertrand, AM; Cabrol, S; Carel, JC; Danton, F; Demay, MC; Dufourg, MN; Esteva, B; Gicquel, C; Heinrichs, C; Houang, M; Jacquemont, ML; Le Bouc, Y; Loeuille, GA; Netchine, I; Perin, L; Petriczko, E; Pinto, G; Rossignol, S; Rousseau, A; Steunou, V; Thibaud, N | 1 |
| Hains, PG; Truscott, RJ | 1 |
| Fanghänel, J; Gedrange, T; Maile, S; Proff, P; Weingärtner, J | 1 |
| Agger, K; Christensen, J; Cloos, PA; Helin, K | 1 |
| Crang, AJ; Jacobson, W | 1 |
| Adams, RL; Burdon, RH | 1 |
| Gomez-Garcia, M; Sala, M; Sala-Trepat, JM; Vedel, M | 1 |
| Harasawa, R; Mitsuoka, T | 1 |
| Klaude, M; von der Decken, A | 2 |
| Hoshino, J; Kröger, H; Seifert, R | 1 |
| Battistella, A; Calderini, G; Crews, FT; Toffano, G | 1 |
| Etkind, PR; Sarkar, NH | 1 |
| Kunnath, L; Locker, J | 1 |
| Ab, G; Gruber, M; Meijlink, FC; Philipsen, JN | 1 |
| Parker, M; White, R | 1 |
| Likhachev, AJ | 2 |
| Brown, A; Huang, RC; Mays-Hoopes, LL | 1 |
| Thakur, MK | 1 |
| Borek, E; Sharma, OK; Waalkes, TP | 1 |
| Jones, PA; Wilson, VL | 1 |
| Anisimov, VN; Keefer, LK; Likhachev, AJ; Ohshima, H; Ovsyannikov, AI; Reist, EJ | 1 |
| Obukhova, LK; Romanenko, EB; Vaniushin, BF | 1 |
| Das, R; Kanungo, MS | 1 |
| Kanungo, MS; Thakur, MK | 2 |
| Dainat, J; Sellinger, OZ | 1 |
| Denisova, NA; Kelly, JF; Kowatch, MA; Roth, GS | 1 |
| Balaghi, M; Wagner, C | 1 |
| Gartler, SM; Goldman, MA | 1 |
| Bakalkin, G; Telkov, M; Terenius, L; Yakovleva, T | 1 |
| Farde, L; Hall, H; Halldin, C; Pauli, S | 1 |
| Alcivar-Warren, AA; Benoit, G; Jue, K; Trasler, JM | 1 |
| Kamiyama, S; Koizumi, A; Kurishita, A; Miyamura, Y; Ono, T; Sakurai, H; Tawa, R; Uehara, Y | 1 |
| Bozas, E; Kitraki, E; Philippidis, H; Stylianopoulou, F | 1 |
| Cunningham, JM; Gumucio, DL; Jane, SM; Ney, PA; Nienhuis, AW | 1 |
| Anderson, CP; Finch, CE; Johnson, SA; Laping, NJ; O'Callaghan, JP; Osterburg, HH; Teter, B | 1 |
| Baylin, SB; Celano, P; Davidson, NE; Hamilton, SR; Issa, JP; Ottaviano, YL | 1 |
| Borisch, B; Fey, MF; Liechti-Gallati, S; Nagel, S; Oestreicher, M; Schneider, V; Theilkäs, L; Tobler, A; von Rohr, A; Ziemiecki, A | 1 |
| Clarke, S | 1 |
| Kurishita, A; Ono, T; Sakurai, H; Tamura, G; Tawa, R | 1 |
| Andrews, LG; Tollefsbol, TO | 1 |
| Kurishita, A; Miyamura, Y; Niwa, O; Ohtsu, H; Ono, T; Sado, T; Watanabe, H | 1 |
| Ben-Baruch, G; Egozi, Y; Haklai, R; Kloog, Y; Marciano, D; Paz, A | 1 |
| Holliday, R | 5 |
| Lindahl, T | 1 |
| Fujii, J; Fusamoto, H; Hayashi, N; Jain, SK; Kamada, T; Miyoshi, E; Sugiyama, T; Taniguchi, N | 1 |
| Cresteil, T; Sonnier, M; Vieira, I | 1 |
| Aoki, Y; Choi, EK; Fujimura, S; Fukuda, Y; Kim, YS; Nakao, K; Nata, M; Nishida, N; Okumoto, T; Ono, T; Sagisaka, K; Uyeno, S; Yoshimoto, T | 1 |
| Blais, N; Brais, E; Busque, L; Gilliland, DG; Lalonde, Y; Maragh, M; Mattioli, J; Mio, R | 1 |
| Béliveau, R; Desrosiers, RR; Pelletier, J | 1 |
| Clark, BF; Rattan, SI | 1 |
| Hoffman, RM | 1 |
| Bottiglieri, T; Lowenthal, D; Parnetti, L | 1 |
| Nappi, AJ; Vass, E | 1 |
| Cataneo, RN; Greenberg, J; Gunawardena, R; Naidu, A; Phillips, M; Rahbari-Oskoui, F | 1 |
| Aoyama, K; Fukushima, S; Hayase, N; Kobayashi, S; Matsubara, K; Ohta, S; Okada, K; Satomi, M; Shimizu, K; Shiono, H; Uezono, T; Yamaguchi, S | 1 |
| Choi, SW; Ghandour, H; Lin, BF; Mason, JB; Selhub, J | 1 |
| Dutton, GJ | 1 |
| Romanenko, EB; Vaniushi, BF | 1 |
| Cornatzer, WE; Duerre, JA; Hoffman, DR | 1 |
| Chang, SH; Lin, FK | 1 |
| Deyl, Z; Helm, R; Vancikova, O | 1 |
| Denko, CW; Messineo, L; Petricevic, M | 1 |
| Berdyshev, GD; Vaniushin, BF; Zin'kovskaia, GG | 1 |
| Kudriashova, IB; Vaniushin, BF | 1 |
| Guldberg, HC; Marsden, CA | 1 |
| Holliday, R; Pugh, JE | 1 |
| Cutler, RG; Ogrodnik, JP; Wulf, JH | 1 |
| Kanduc, D; Prisco, M | 1 |
| Huxtable, RJ; Lleu, PL | 1 |
| Cauchi, MN; Loo, LS | 1 |
| Clark, BF; Derventzi, A; Rattan, SI | 1 |
| Katakura, R; Kayama, T; Ono, T; Sagisaka, K; Sakurai, H; Tawa, R; Ueno, S; Yamamoto, K; Yamamoto, Y; Yoshimoto, T | 1 |
| Kanungo, MS; Saran, S | 2 |
| Ghazi, H; Gonzales, FA; Jones, PA | 1 |
| Negoro, S | 1 |
| Pagani, F; Toniolo, D; Vergani, C | 1 |
| Breslow, JL; Eisenberg, S; Kafri, T; O'Connell, A; Razin, A; Shemer, R | 1 |
| Giuliani, L; Pacifici, GM; Santerini, S | 1 |
| Kosugi, A; Singer, A; Takahama, Y | 1 |
| Prasad, S; Thakur, MK | 2 |
| Slagboom, PE; Uitterlinden, AG; Vijg, J | 1 |
| de Leeuw, WJ; Slagboom, PE; Vijg, J | 2 |
| Kaur, J; Thakur, MK | 1 |
| Ferluga, J | 2 |
| Golbus, J; Palella, TD; Richardson, BC | 1 |
| Bouhours, D; Bouhours, JF; Hansson, GC; Karlsson, H; Larson, G; Pimlott, W | 1 |
| Hirose, S; Kurishita, A; Okada, S; Ono, T; Tawa, R | 1 |
| Brian, WR; Guengerich, FP; Iwasaki, M; Molowa, DT; Raucy, JL; Sari, MA; Vandenbranden, M; Wrighton, SA | 1 |
| Bélanger, L; Chevrette, M; Guertin, M; LaRue, H; Turcotte, B | 1 |
| Chanderkar, LP; Kim, S; Paik, WK | 1 |
| Kanungo, MS; Rath, PC | 1 |
| Mays-Hoopes, LL | 2 |
| Beck, J; Burns, LJ; Ginder, GD; Glauber, JG | 1 |
| Kokuryu, H; Kurishita, A; Okada, S; Ono, T; Uehara, Y | 1 |
| Dalrymple, S; Howlett, D; Mays-Hoopes, LL | 1 |
| Okada, S; Ono, T; Shinya, K; Uehara, Y | 1 |
| Chaturvedi, MM; Kanungo, MS | 1 |
| Brice, M; Enver, T; Karlinsey, J; Papayannopoulou, T; Zhang, JW | 1 |
| Slagboom, PE; Vijg, J | 1 |
| Oppenheimer, JH; Schwartz, HL; Strait, K; Wong, NC | 1 |
| Blake, TJ; Drinkwater, RD; Morley, AA; Turner, DR | 1 |
| Okada, S; Ono, T; Takahashi, N | 1 |
| Ehrlich, M; Wang, RY; Zhang, XY | 1 |
| Duerre, JA; Fetters, HA | 1 |
| Cordasco, DM; Critchett, DJ; Joseph, JA; Lippa, AS; Loullis, CC; Rotrosen, J | 1 |
| Hirose, S; Okada, S; Ono, T; Shinya, K; Tawa, R | 1 |
| Chanderkar, LP; Kim, S; Knobler, RL; Lublin, FD; Paik, WK; Shanker, G | 1 |
| Hacobian, N; Lotlikar, PD; Magee, PN; Prasanna, HR | 1 |
| Lijinsky, W; Thomas, BJ | 1 |
| Bykhovskiĭ, VIa; Dmitrovskiĭ, AA; Liudkovskaia, IV; Podlepa, EM | 1 |
| Cook, LL; Gafni, A | 1 |
| Ames, BN; Park, JW | 1 |
| Deguchi, Y; Hara, H; Kishimoto, S; Negoro, S; Nishio, S | 1 |
| Heyliger, CE; McNeill, JH; Prakash, AR | 1 |
| Hoenders, HJ; van den Oetelaar, PJ | 1 |
| Kramer, CM; Sellinger, OZ | 1 |
| Eichhorn, GL; Mays-Hoopes, LL; Singhal, RP | 1 |
| Butcher, HC; Chao, W; Huang, RC; Mays-Hoopes, L | 1 |
| Snoswell, AM; Xue, GP | 1 |
| Vaniushin, BF; Zhavoronkova, EN | 1 |
| Cutler, RG; Ma, S; Smith, RA; Wilson, VL | 1 |
| Anisimov, VN; Likhachev, AIa; Ovsiannikov, AI | 2 |
| Dhalla, NS; Jasmin, G; Okumura, K; Panagia, V | 1 |
| Korsakov, MV; Ovsiannikov, AI | 1 |
| Carnegie, PR; Jones, GM | 1 |
| Brush, AH | 1 |
| Hansen, LG; Hodgson, E | 1 |
| Duerre, JA; Lee, CT | 2 |
| Anderson, PJ | 1 |
| Bur'ianov, IaI; Korsunskiĭ, OF; Tret'iak, TM | 1 |
| Rosen, L; Wust, CJ | 1 |
| Belozersky, AN; Klimenko, VV; Nemirovsky, LE; Vanyushin, BF; Vasiliev, VK | 1 |
| Seemayer, G | 1 |
| Bruce, A; Svennerholm, L | 1 |
| Hill, RM; Horning, EC; Horning, MG; Hung, A | 1 |
| Curri, SB | 1 |
| Lawson, D; Lee, HW; Paik, WK | 1 |
| Bache, CA; Gutenmann, WH; Lisk, DJ | 1 |
35 review(s) available for isomethyleugenol and Aging
| Article | Year |
|---|---|
Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases.
Topics: Aging; Alternative Splicing; Brain; Humans; Methylation; Neurodegenerative Diseases; RNA; RNA Editing; RNA, Messenger | 2023 |
Epigenetic Regulators of Mesenchymal Stem/Stromal Cell Lineage Determination.
Topics: Acetylation; Aging; Cell Differentiation; Cell Lineage; DNA Methylation; Epigenesis, Genetic; Epigenetic Repression; Gene Expression Regulation; Histone Code; Humans; Mesenchymal Stem Cells; Methylation; Osteoporosis; Transcriptional Activation; Weight-Bearing | 2020 |
Lessons from animal nutritionists: dietary amino acid requirement studies and considerations for healthy aging studies.
Topics: Aging; Amino Acids; Amino Acids, Sulfur; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Cell Differentiation; Cell Proliferation; Dietary Proteins; Energy Metabolism; Lipogenesis; Longevity; Mechanistic Target of Rapamycin Complex 1; Methionine; Methylation; Reactive Oxygen Species; Signal Transduction | 2018 |
The role of mitochondria in stem cell fate and aging.
Topics: Acetylation; Aging; Animals; Cell Differentiation; Cellular Senescence; DNA, Mitochondrial; Energy Metabolism; Humans; Methylation; Mitochondria; Mitochondrial Dynamics; Mitophagy; Mutation; Reactive Oxygen Species; Stem Cells; Unfolded Protein Response | 2018 |
Epigenetic regulation of memory by acetylation and methylation of chromatin: implications in neurological disorders, aging, and addiction.
Topics: Acetylation; Aging; Alzheimer Disease; Animals; Chromatin; DNA Methylation; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Memory; Methylation; Nerve Growth Factors; Nervous System Diseases; Neuronal Plasticity; Nitric Oxide; Nitrosation; Protein Processing, Post-Translational; Substance-Related Disorders | 2015 |
Base excision repair: a critical player in many games.
Topics: Aging; Chromatin; DNA Damage; DNA Glycosylases; DNA Repair; Humans; Methylation; Oxidative Stress; Protein Processing, Post-Translational | 2014 |
Histone methylation and aging: lessons learned from model systems.
Topics: Aging; Animals; DNA Methylation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Models, Biological; Progeria; Protein Processing, Post-Translational | 2014 |
Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process.
Topics: Aging; Animals; Chromatin Assembly and Disassembly; Citric Acid Cycle; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Methylation; Mitochondria; Signal Transduction | 2014 |
Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.
Topics: Aging; Animals; Biomarkers; Chromobox Protein Homolog 5; Epigenesis, Genetic; Histones; Humans; Lysine; Methylation; Stem Cells | 2015 |
Regenerating muscle with arginine methylation.
Topics: Aging; Animals; Arginine; Humans; Methylation; Muscle Proteins; Muscles; Muscular Diseases; Myoblasts; Protein-Arginine N-Methyltransferases; Regeneration | 2017 |
Folate, DNA damage and the aging brain.
Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil | 2010 |
Epigenetic alterations in aging.
Topics: Acetylation; Age Factors; Aging; Aging, Premature; Animals; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylation; Neoplasms; RNA, Untranslated | 2010 |
Epigenetic changes associated with oocyte aging.
Topics: Acetylation; Aging; Animals; DNA Methylation; Epigenesis, Genetic; Female; Histones; Humans; Maternal Age; Methylation; Oocytes | 2012 |
[Drosophila DNA and histone methylation and life limits].
Topics: Aging; Animals; DNA Methylation; Drosophila; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Methylation | 2012 |
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Topics: Aging; Alzheimer Disease; Animals; Apoptosis; Cell Death; Depressive Disorder; Folic Acid; Homocysteine; Humans; Mental Disorders; Methylation; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Parkinson Disease; Schizophrenia; Stroke | 2003 |
Advancing age and other factors influencing the balance between amino acid requirements and toxicity.
Topics: Aging; Amino Acids; Amino Acids, Sulfur; Cardiovascular Diseases; Cystathionine beta-Synthase; Glutathione; Humans; Methylation; Nutritional Requirements; Nutritional Status; Risk Factors | 2004 |
The nutritional relationship linking sulfur to nitrogen in living organisms.
Topics: Aging; Animals; Body Composition; Diet; Homeostasis; Homocysteine; Humans; Methionine; Methylation; Nitrates; Nitrogen; Nutritional Physiological Phenomena; Oxidation-Reduction; Plants, Edible; Prealbumin; Protein Deficiency; Stress, Physiological; Sulfates; Sulfur | 2006 |
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.
Topics: Aging; Animals; Cell Differentiation; Histones; Humans; Methylation; Models, Biological; Neoplasms; Oxidoreductases, N-Demethylating; Phylogeny | 2008 |
DNA methylation in eukaryotes.
Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin | 1982 |
DNA repair induced by alkylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Cricetinae; Dimethylhydrazines; Dimethylnitrosamine; DNA Repair; Ethylnitrosourea; Mesocricetus; Methylation; Methylnitrosourea; Rats | 1983 |
Reactivation of inactive X-linked genes.
Topics: Aging; Animals; Azacitidine; Cell Fusion; Dosage Compensation, Genetic; Gene Expression Regulation, Developmental; Germ Cells; Humans; Methylation; X Chromosome | 1994 |
Protein methylation.
Topics: Aging; Amino Acid Sequence; Amino Acids; Animals; Eukaryotic Cells; Methylation; Molecular Sequence Data; Prokaryotic Cells; Protein Methyltransferases; Protein Processing, Post-Translational; Proteins; S-Adenosylmethionine | 1993 |
Epigenetic inheritance based on DNA methylation.
Topics: Aging; Animals; Base Sequence; Cell Line; DNA; Fragile X Syndrome; Genetic Diseases, Inborn; Humans; Mammals; Methylation; Neoplasms; Repetitive Sequences, Nucleic Acid; Sex Chromosome Aberrations; X Chromosome; Zea mays | 1993 |
Instability and decay of the primary structure of DNA.
Topics: Aging; Animals; Base Sequence; Carcinogens; DNA; Humans; Hydrolysis; Methylation; Molecular Sequence Data; Mutagenesis; Nucleic Acid Denaturation; Oxidation-Reduction; Paleontology; Spores | 1993 |
Intracellular protein synthesis, modifications and aging.
Topics: Adenosine Diphosphate Ribose; Aging; Animals; Cell Compartmentation; Glycosylation; Methylation; Oxidation-Reduction; Peptide Chain Elongation, Translational; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational | 1996 |
Methioninase: a therapeutic for diseases related to altered methionine metabolism and transmethylation: cancer, heart disease, obesity, aging, and Parkinson's disease.
Topics: Aging; Animals; Carbon-Sulfur Lyases; Drug Interactions; Drug Therapy, Combination; Heart Diseases; Humans; Methionine; Methylation; Neoplasms; Obesity; Parkinson Disease; Recombinant Proteins | 1997 |
Role of homocysteine in age-related vascular and non-vascular diseases.
Topics: Aged; Aging; Alcoholism; Central Nervous System; Cerebrovascular Disorders; Cognition; Coronary Disease; Depression; Estrogens; Female; Folic Acid Deficiency; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methylation; Peripheral Vascular Diseases; Renal Replacement Therapy; Vascular Diseases; Vitamin B 12 Deficiency | 1997 |
Developmental aspects of drug conjugation, with special reference to glucuronidation.
Topics: Acetylation; Acetylcysteine; Acylation; Aging; Amino Acids; Animals; Chick Embryo; Enzyme Induction; Fetus; Glucuronates; Glucuronosyltransferase; Glutathione; Glutathione Transferase; Glycosides; Humans; Liver; Methylation; Pharmaceutical Preparations; Sulfates; Uridine Diphosphate Glucuronic Acid | 1978 |
Catechol-O-methyl transferase: pharmacological aspects and physiological role.
Topics: Aging; Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Chickens; Female; Humans; Hypertension; Invertebrates; Isoenzymes; Isomerism; Kinetics; Mental Disorders; Methylation; Molecular Weight; Neoplasms; Plants; Pyrogallol; Rats; Subcellular Fractions; Tropolone; Uterus; Vertebrates | 1975 |
Protein synthesis, posttranslational modifications, and aging.
Topics: Adenosine Diphosphate Ribose; Aging; Amides; Animals; DNA Replication; Glycation End Products, Advanced; Humans; Isomerism; Methylation; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Proteins; Signal Transduction | 1992 |
Potential role of anti-oncogenes in aging.
Topics: Aging; Cell Survival; Cell Transformation, Neoplastic; DNA; DNA Tumor Viruses; Humans; Methylation; Oncogene Proteins; Oncogenes; Phenotype | 1990 |
Age-related changes in DNA methylation: do they represent continued developmental changes?
Topics: Aging; alpha-Fetoproteins; Animals; DNA; Globins; Humans; Methylation; Repetitive Sequences, Nucleic Acid; Serum Albumin; Vitellogenins; X Chromosome | 1989 |
DNA methylation in aging and cancer.
Topics: Aging; Animals; Carcinogens; DNA; Humans; Methylation | 1989 |
Genetic instability and aging: theories, facts, and future perspectives.
Topics: Aging; Animals; DNA; Gene Expression; Gene Rearrangement; Humans; Methylation; Mutation; Proteins; RNA, Messenger | 1989 |
The inheritance of epigenetic defects.
Topics: Aging; Animals; DNA; DNA Repair; Genetic Diseases, Inborn; Humans; Meiosis; Methylation; Mutation | 1987 |
5 trial(s) available for isomethyleugenol and Aging
| Article | Year |
|---|---|
Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Beverages; Cacao; Catechin; Cross-Over Studies; Flavonoids; Glucuronides; Half-Life; Humans; Intestinal Absorption; Kinetics; Lactones; Male; Methylation; Patient Dropouts; Renal Elimination; Stereoisomerism; Sulfuric Acid Esters; Young Adult | 2015 |
Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans.
Topics: Adaptation, Physiological; Adolescent; Aged; Aged, 80 and over; Aging; Down-Regulation; Exercise; Female; Gene Expression Regulation; Humans; Male; Metabolism; Methylation; Middle Aged; Mitochondria; Muscle Proteins; Muscle, Skeletal; Physical Fitness; Protein Biosynthesis; Proteome; Young Adult | 2017 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocysteine; Methionine; Methylation | 2006 |
Variability in D2-dopamine receptor density and affinity: a PET study with [11C]raclopride in man.
Topics: Adult; Aging; Brain; Brain Chemistry; Dopamine Antagonists; Female; Humans; Image Processing, Computer-Assisted; Male; Methylation; Raclopride; Receptors, Dopamine D2; Salicylamides; Sex Characteristics; Tomography, Emission-Computed | 1995 |
N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test.
Topics: Aged; Aging; Aldehyde Oxidase; Aldehyde Oxidoreductases; Brain; Carbolines; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Humans; Isoquinolines; Male; Methylation; Middle Aged; Niacinamide; Parkinson Disease | 2000 |
229 other study(ies) available for isomethyleugenol and Aging
| Article | Year |
|---|---|
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
Topics: Aging; Animals; Cell Line; Cell Proliferation; Endothelial Cells; Glycosylation; Glyoxal; Humans; Lysine; Methylation; Mice; Mice, Inbred C57BL; Microtubules; Primary Cell Culture; Protein Processing, Post-Translational; Proteins; Proteomics; Proteostasis; Tubulin | 2021 |
Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile.
Topics: Aging; Animals; Cellular Senescence; Cognition; Dasatinib; Hippocampus; Histones; Inflammation; Male; Methylation; Mice; Neuronal Plasticity; Quercetin; Rats; Rats, Wistar | 2022 |
Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylation.
Topics: Adenosine Monophosphate; Aging; Animals; Circadian Clocks; Circadian Rhythm; Gene Expression; Histone Code; Histones; Iron; Mammals; Methylation; Mice; Period Circadian Proteins; Transcription Factors | 2022 |
Premature Aging of the Airway Epithelium in Chronic Obstructive Pulmonary Disease in People Living with HIV.
Topics: Aging; Aging, Premature; Epithelium; HIV Infections; Humans; Methylation; Pulmonary Disease, Chronic Obstructive | 2022 |
Bone Marrow Mesenchymal Stem Cells Reversed Ovarian Aging-related m6A RNA Methylation Modification Profile in Aged Granulosa Cells.
Topics: Aging; Animals; Female; Granulosa Cells; Histones; Hydrogen Peroxide; Macaca mulatta; Mesenchymal Stem Cells; Methylation; RNA | 2023 |
Methylation-Based Biological Age and Hypertension Prevalence and Incidence.
Topics: Aged; Aging; Blood Pressure; Female; Humans; Hypertension; Incidence; Methylation; Prevalence; Prospective Studies; Risk Factors | 2023 |
Establishing the contribution of active histone methylation marks to the aging transcriptional landscape of Drosophila photoreceptors.
Topics: Aging; Animals; Chromatin; Drosophila; Drosophila Proteins; Histone-Lysine N-Methyltransferase; Histones; Mammals; Methylation | 2023 |
Bloom syndrome patients and mice display accelerated epigenetic aging.
Topics: Aging; Aging, Premature; Animals; Bloom Syndrome; DNA Methylation; Epigenesis, Genetic; Humans; Methylation; Mice | 2023 |
Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae.
Topics: Aging; Histones; Methylation; Methyltransferases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin-Conjugating Enzymes | 2023 |
Decoding the transcriptomic expression and genomic methylation patterns in the tendon proper and its peritenon region in the aging horse.
Topics: Aging; Animals; Genomics; Horse Diseases; Horses; Methylation; Tendons; Transcriptome | 2023 |
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; tau Proteins | 2019 |
Hdac3, Setdb1, and Kap1 mark H3K9me3/H3K14ac bivalent regions in young and aged liver.
Topics: Acetylation; Aging; Animals; Chromatin; Chromatin Immunoprecipitation Sequencing; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Histones; Lipid Metabolism; Liver; Male; Mass Spectrometry; Methylation; Mice; Mice, Inbred C57BL; Nucleosomes; Protein Processing, Post-Translational; Proteome; Tripartite Motif-Containing Protein 28 | 2020 |
Histone H3K9 methylation is involved in temporomandibular joint osteoarthritis.
Topics: Aging; Animals; Apoptosis; Cell Proliferation; Female; Histones; Lysine; Methylation; Mice; Mice, Inbred C57BL; Osteoarthritis; Temporomandibular Joint | 2020 |
Two conserved epigenetic regulators prevent healthy ageing.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cognition; Cognitive Dysfunction; Epigenesis, Genetic; Healthy Aging; Histone-Lysine N-Methyltransferase; Histones; Humans; Longevity; Lysine; Male; Memory; Methylation; Mice; Mitochondria; Neurons; Proteins; RNA Interference; Spatial Learning; Transcription Factors, General | 2020 |
Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway.
Topics: Aging; Animals; Disease Models, Animal; DNA-Binding Proteins; Female; Hematopoietic Stem Cells; Histones; Humans; Hypercholesterolemia; Male; Methylation; Mice; Mice, Knockout; Phenotype; Proto-Oncogene Proteins | 2020 |
Expression of G9a in Auditory Cortex Is Downregulated in a Rat Model of Age-Related Hearing Loss.
Topics: Aging; Animals; Auditory Cortex; Auditory Threshold; Down-Regulation; Gene Expression Regulation; Hair Cells, Auditory; Histone Code; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Models, Animal; Nerve Tissue Proteins; Presbycusis; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley | 2021 |
Glutathionylation Decreases Methyltransferase Activity of PRMT5 and Inhibits Cell Proliferation.
Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Cell Line, Tumor; Cell Proliferation; Databases, Protein; G2 Phase Cell Cycle Checkpoints; Glutaredoxins; Glutathione; HEK293 Cells; Histones; Humans; Hydrogen Peroxide; Kidney; Methylation; Mice; Oxidative Stress; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Arginine N-Methyltransferases; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation | 2020 |
Age-associated epigenetic change in chimpanzees and humans.
Topics: Aging; Animals; Blood; Epigenesis, Genetic; Humans; Methylation; Pan troglodytes | 2020 |
Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Hypertension; Kidney; Methylation; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress | 2020 |
Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations.
Topics: Aging; Animals; Biomarkers; Bone Morphogenetic Proteins; Bone Regeneration; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Female; Histones; Ketoglutaric Acids; Male; Mesenchymal Stem Cells; Methylation; Mice; Osteogenesis; Osteoporosis; Signal Transduction | 2020 |
Arginine site 264 in murine estrogen receptor-α is dispensable for the regulation of the skeleton.
Topics: Absorptiometry, Photon; Aging; Animals; Arginine; Bone and Bones; Bone Density; Endothelium; Estrogen Receptor alpha; Estrogens; Female; Methylation; Mice; Organ Size; Ovariectomy; Spine; Tibia; Tomography, X-Ray Computed | 2021 |
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Humans; Methylation; Methyltransferases; Mice; Neurodegenerative Diseases; RNA Stability | 2021 |
17β-Estradiol alleviates cardiac aging induced by d-galactose by downregulating the methylation of autophagy-related genes.
Topics: Aging; Autophagy; Estradiol; Galactose; Methylation | 2021 |
Epigenetic clock and methylation studies in elephants.
Topics: Aging; Animals; Elephants; Epigenomics; Methylation | 2021 |
Expression, methylation and prognostic feature of EMILIN2 in Low-Grade-Glioma.
Topics: Adult; Aging; Biomarkers, Tumor; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Humans; Kaplan-Meier Estimate; Male; Methylation; Middle Aged; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Survival Analysis; Transcriptome | 2021 |
The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging.
Topics: 3' Untranslated Regions; Adenosine; Aging; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Case-Control Studies; Cell Line; Down-Regulation; Female; Gene Silencing; Granulosa Cells; Humans; Methylation; Models, Biological; Ovary; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; RNA Stability; RNA, Messenger; Up-Regulation | 2021 |
The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice.
Topics: Aging; Animals; Cell Differentiation; DNA-Binding Proteins; Epidermis; Histone-Lysine N-Methyltransferase; Histones; Hyperplasia; Keratinocytes; Methylation; Mice; Mutagenesis; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Wound Healing | 2017 |
Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
Topics: Aging; Animals; Caenorhabditis elegans; Dietary Fats; Down-Regulation; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Germ Cells; Histone-Lysine N-Methyltransferase; Histones; Intestinal Mucosa; Intestines; Lipid Metabolism; Longevity; Lysine; Methylation; Ribosomal Protein S6 Kinases, 70-kDa; Stearoyl-CoA Desaturase; Up-Regulation | 2017 |
Accumulation of histone variant H3.3 with age is associated with profound changes in the histone methylation landscape.
Topics: Aging; Animals; Carcinoma, Hepatocellular; Cells, Cultured; Hepatocytes; Histone Code; Histones; Humans; Liver Neoplasms; Lysine; Male; Methylation; Mice, Inbred C57BL; Protein Isoforms; Protein Processing, Post-Translational | 2017 |
Structural elucidation and antiaging activity of polysaccharide from Paris polyphylla leaves.
Topics: Aging; Animals; Antioxidants; Chromatography, Gel; Liliaceae; Liver; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Methylation; Mice; Plant Leaves; Polysaccharides; Serum; Spectroscopy, Fourier Transform Infrared; Spleen; Thymus Gland | 2018 |
Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches.
Topics: Aging; Animals; Cell Differentiation; Cell Movement; Chromatin; Enhancer of Zeste Homolog 2 Protein; Gene Knockout Techniques; Histone-Lysine N-Methyltransferase; Histones; Homologous Recombination; Integrases; Lysine; Methylation; Mice; Neurogenesis; Neurons; Organ Specificity; Recombinant Proteins; S Phase | 2018 |
Demethylation of methionine and keratin damage in human hair.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Child, Preschool; Copper; Female; Hair; Homocysteine; Humans; Infant; Iron; Keratins; Male; Methionine; Methylation; Middle Aged | 2018 |
The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
Topics: Aging; Animals; Arginine Vasopressin; Dehydration; Genome; Male; Mass Spectrometry; Methylation; Neurosecretory Systems; Osmolar Concentration; Osmoregulation; Pituitary Gland, Posterior; Promoter Regions, Genetic; Rats, Wistar; Supraoptic Nucleus; Transcription, Genetic; Transcriptome | 2018 |
Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability.
Topics: Adult; Aging; Argonaute Proteins; Cells, Cultured; Down-Regulation; Gene Expression; Humans; Male; Methylation; Methyltransferases; Middle Aged; RNA; RNA Stability | 2018 |
Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.
Topics: Aging; Animals; Archaeal Proteins; Chlorocebus aethiops; Coronavirus; Coronavirus Infections; Disease Models, Animal; Immunocompromised Host; Methylation; Methyltransferases; Mice; Mice, Inbred BALB C; Mutation; Severe acute respiratory syndrome-related coronavirus; Vaccines, Attenuated; Vero Cells; Viral Nonstructural Proteins; Viral Vaccines; Virus Replication | 2018 |
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
Topics: Aging; Amyloid beta-Peptides; Animals; Anxiety; Brain; Cell Survival; Cerebral Cortex; Choline; CpG Islands; Diet; DNA Methylation; Epigenesis, Genetic; Folic Acid; Glutamic Acid; Homocystinuria; Liver; Male; Memory Disorders; Memory, Short-Term; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Mice, Inbred BALB C; Muscle Spasticity; Nerve Growth Factors; Neurons; Phospholipids; Psychotic Disorders; RNA, Messenger; S-Adenosylmethionine; Synaptic Transmission | 2019 |
MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging.
Topics: 3' Untranslated Regions; Aging; Animals; Base Sequence; Brain; Drosophila melanogaster; Drosophila Proteins; Gene Expression Profiling; Histones; Lysine; Methylation; MicroRNAs; Models, Biological; Molecular Chaperones; Mutation; Nerve Degeneration; Peptides; Polycomb Repressive Complex 2; Protein Aggregates; Transcriptome | 2018 |
Social Behaviour and Epigenetic Status in Adolescent and Adult Rats: The Contribution of Early-Life Stressful Social Experience.
Topics: Acetylation; Aging; Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Epigenesis, Genetic; Female; Histones; Interpersonal Relations; Methyl-CpG-Binding Protein 2; Methylation; Rats, Wistar; Repressor Proteins; RNA, Messenger; Social Behavior; Stress, Psychological | 2019 |
Your DNA May Appear Older Than You Think.
Topics: Aging; Breast; Breast Neoplasms; DNA; Humans; Methylation | 2019 |
KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation.
Topics: Aging; Cell Line; Cell Nucleus; HEK293 Cells; Heterochromatin; Histone-Lysine N-Methyltransferase; Histones; Humans; Lamin Type B; Methylation | 2019 |
Regulation of S-Nitrosylation in Aging and Senescence.
Topics: Aging; Aldehyde Oxidoreductases; Animals; Cellular Senescence; Humans; Long-Term Potentiation; Methylation; Mice; Neuronal Plasticity; Nitrosation | 2019 |
Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications.
Topics: Acetylation; Aging; Animals; Avoidance Learning; Chromatin; Epigenesis, Genetic; Hippocampus; Histones; Lysine; Male; Memory; Methylation; Physical Conditioning, Animal; Promoter Regions, Genetic; Rats, Wistar; Survival Rate | 2019 |
Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
Topics: Aging; Epigenesis, Genetic; Humans; Methylation; Mutation; Werner Syndrome; Werner Syndrome Helicase | 2019 |
Age-related changes in histone modification in rat gastrocnemius muscle.
Topics: Acetylation; Aging; Animals; Histone Code; Male; Methylation; Muscle, Skeletal; Myosin Heavy Chains; Rats, Wistar | 2019 |
Prevention of Adult Colitis by Oral Ferric Iron in Juvenile Mice Is Associated with the Inhibition of the Tbet Promoter Hypomethylation and Gene Overexpression.
Topics: Administration, Oral; Adult; Aging; Animals; Colitis; CpG Islands; Drug Compounding; Ferric Compounds; Gene Expression Regulation; Humans; Male; Methylation; Mice; Mice, Inbred BALB C; Promoter Regions, Genetic; Transcription Factors | 2019 |
The protein-protein interaction network of the human Sirtuin family.
Topics: Acetylation; Aging; Computational Biology; Databases, Protein; Humans; Methylation; Neoplasms; Phosphorylation; Protein Interaction Mapping; Protein Interaction Maps; Protein Processing, Post-Translational; Sirtuins | 2013 |
Tissue-specific modification of clock methylation in aging mice.
Topics: Aging; Animals; CLOCK Proteins; DNA; DNA Primers; Gastric Mucosa; Male; Methylation; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Promoter Regions, Genetic; Sulfites | 2013 |
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape.
Topics: Aging; Cell Line; Cell Proliferation; Cells, Cultured; Chromatin; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Fibroblasts; Gene Expression Regulation; Histones; Humans; Lamin Type B; Methylation; Progeria; Protein Structure, Tertiary | 2013 |
Prenatal methyl-donor supplementation augments colitis in young adult mice.
Topics: Aging; Animals; Animals, Newborn; Colitis; Diet; Dietary Supplements; Feces; Female; Intestinal Mucosa; Male; Methylation; Mice, Inbred C57BL; Microbiota; PPAR alpha; Pregnancy; Prenatal Exposure Delayed Effects | 2013 |
Aging is associated with increased regulatory T-cell function.
Topics: Aging; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Epigenomics; Forkhead Transcription Factors; Male; Methylation; Mice; Mice, Inbred C57BL; Oxidation-Reduction; T-Lymphocytes, Regulatory | 2014 |
Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila.
Topics: Aging; Animals; Argonaute Proteins; Drosophila; Drosophila Proteins; Methylation; Methyltransferases; MicroRNAs; Mutation; Neurons; Protein Isoforms | 2014 |
Broad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns.
Topics: Aging; Animals; Animals, Newborn; Cell Cycle; Cell Differentiation; Chromatin Immunoprecipitation; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Ontology; Histones; Kidney; Lung; Lysine; Male; Methylation; Mice, Inbred C57BL; Neurons; Protein Processing, Post-Translational; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2014 |
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease.
Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins | 2014 |
Rcor2 underexpression in senescent mice: a target for inflammaging?
Topics: Aging; Analysis of Variance; Animals; Astrocytes; Brain; Co-Repressor Proteins; Cytokines; Encephalitis; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Histones; Interleukin-6; Lipopolysaccharides; Male; Methylation; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Repressor Proteins | 2014 |
Age-dependent clinical prognostic value of histone modifications in colorectal cancer.
Topics: Acetylation; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Biomarkers, Tumor; Cohort Studies; Colorectal Neoplasms; Epigenesis, Genetic; Female; Gene Expression Profiling; Histones; Humans; Male; Methylation; Middle Aged; Prognosis; Translational Research, Biomedical | 2015 |
Histone methylation patterns in astrocytes are influenced by age following ischemia.
Topics: Acetylation; Acetyltransferases; Aging; Animals; Astrocytes; Brain Ischemia; Cerebral Cortex; Female; Histones; Lysine; Methylation; Methyltransferases; Rats, Sprague-Dawley | 2015 |
Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake.
Topics: Aged; Aged, 80 and over; Aging; Autonomic Nervous System Diseases; Bradycardia; Cohort Studies; Diet; Epigenomics; Flavonoids; Geriatric Assessment; Heart Conduction System; Humans; Immunomodulation; Male; Methylation; Particulate Matter; Prognosis; Prospective Studies; Survival Rate; Toll-Like Receptor 2 | 2015 |
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.
Topics: Aging; Animals; Caenorhabditis elegans; Drosophila melanogaster; Gene Expression Regulation; Histones; Longevity; Lysine; Methylation | 2015 |
HIV-1 Infection Accelerates Age According to the Epigenetic Clock.
Topics: Adolescent; Adult; Aged; Aging; Blood Cells; Brain; DNA; Epigenesis, Genetic; HIV Infections; HIV-1; Humans; Male; Methylation; Middle Aged; Young Adult | 2015 |
Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging.
Topics: Adult; Aged; Aging; Algorithms; Cells, Cultured; Cluster Analysis; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Forkhead Transcription Factors; Gene Expression Profiling; Histones; Humans; Male; Methylation; Middle Aged; Protein Biosynthesis; Skin; Statistics, Nonparametric | 2015 |
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Azacitidine; Brain; Cell Death; D-Aspartate Oxidase; D-Aspartic Acid; Decitabine; Embryo, Mammalian; Enzyme Inhibitors; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2016 |
Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.
Topics: Aging; Animals; DNA Damage; Drosophila melanogaster; Drosophila Proteins; Fat Body; Gene Expression Regulation, Developmental; Heterochromatin; Histones; Lamins; Lysine; Methylation; Models, Biological; Retroelements | 2016 |
sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation.
Topics: Aging; Animals; Cell Differentiation; Cell Proliferation; Enzyme Activation; Epidermis; ErbB Receptors; Gene Expression Profiling; Group II Phospholipases A2; Hair Follicle; Histones; Homeostasis; Hyperplasia; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Lysine; Methylation; Mice, Transgenic; Parakeratosis; Proto-Oncogene Proteins c-jun; Sebaceous Glands; Signal Transduction; Stem Cells | 2016 |
Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila.
Topics: Aging; Animals; Brain; Down-Regulation; Drosophila melanogaster; Drosophila Proteins; Female; Heterochromatin; Intestines; Intracellular Signaling Peptides and Proteins; Longevity; Male; Methionine; Methylation; S-Adenosylhomocysteine | 2016 |
Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes.
Topics: Aging; Animals; Chromosomes, Mammalian; Histones; Lysine; Metaphase; Methylation; Mice; Oocytes; Ovulation; RNA-Binding Proteins; RNA, Messenger; Spindle Apparatus | 2016 |
Aging Triggers a Repressive Chromatin State at Bdnf Promoters in Hippocampal Neurons.
Topics: Acetylation; Aging; Animals; Brain-Derived Neurotrophic Factor; Cholesterol; Chromatin; Cognition; Epigenesis, Genetic; Hippocampus; Histones; Long-Term Potentiation; Lysine; Methylation; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcription, Genetic; Voriconazole | 2016 |
A-to-I RNA editing of the IGFBP7 transcript increases during aging in porcine brain tissues.
Topics: Aging; Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Brain Mapping; Cerebellum; Chromosome Mapping; Female; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Lung; Lysine; Methylation; Mice; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sulfates; Swine | 2016 |
Age-related difference of site-specific histone modifications in rat liver.
Topics: Acetylation; Age Factors; Aging; Amino Acid Sequence; Animals; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Histones; Liver; Lysine; Male; Methylation; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Serine | 2009 |
Age-related methylation in normal colon mucosa differs between the proximal and distal colon in patients who underwent colonoscopy.
Topics: Adult; Aged; Aged, 80 and over; Aging; Colon; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Estrogen Receptor alpha; Female; Humans; Intestinal Mucosa; Male; Methylation; Middle Aged; MyoD Protein; Promoter Regions, Genetic; Statistics as Topic | 2008 |
Differential expression of epigenetic modulators during human embryonic stem cell differentiation.
Topics: Aging; Alkaline Phosphatase; Animals; Biomarkers; Cell Differentiation; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; Embryonic Stem Cells; Epigenesis, Genetic; Fibroblasts; Fibronectins; Gene Expression Regulation; Histones; Humans; Immunohistochemistry; Methylation; Mice; Microscopy, Phase-Contrast; Proto-Oncogene Proteins c-myc; Telomerase | 2009 |
Methylation of estrogen receptor 1 in colorectal adenomas is not age-dependent, but is correlated with K-ras mutation.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aging; Codon; Colorectal Neoplasms; DNA Primers; Estrogen Receptor alpha; Female; Genes, ras; Humans; Male; Methylation; Middle Aged; Mutation; Smoking | 2009 |
Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apolipoproteins E; Brain Chemistry; Docosahexaenoic Acids; Fatty Acids; Female; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Male; Methylation; Middle Aged; Neocortex; Postmortem Changes; Sex Characteristics | 2010 |
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.
Topics: Aging; Autophagy; Gene Deletion; Genome, Fungal; Longevity; Methylation; Mitochondria; Protein Biosynthesis; Protein Transport; RNA, Transfer; Saccharomyces cerevisiae; Vacuoles | 2010 |
Methylation of polyphenols with vicinal hydroxyl groups: A protection pathway increasing organismal lifespan.
Topics: Aging; Flavonoids; Free Radical Scavengers; Fungal Proteins; Methylation; Methyltransferases; Phenols; Podospora; Polyphenols; Protein O-Methyltransferase; Reactive Oxygen Species | 2010 |
Hepatocyte nuclear factor 4α regulates expression of the mouse female-specific Cyp3a41 gene in the liver.
Topics: Acetylation; Aging; Animals; Cell Nucleus; Cells, Cultured; Chromatin; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Female; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 4; Histones; Human Growth Hormone; Hypophysectomy; Liver; Male; Methylation; Mice; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Sex Characteristics | 2011 |
The correlation between the clinical laboratory data and the telomere length in peripheral blood leukocytes of Japanese female patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amlodipine; Antihypertensive Agents; Blotting, Southern; Creatinine; Cross-Sectional Studies; Female; Humans; Hypertension; Japan; Leukocytes; Methylation; Middle Aged; Telomere | 2011 |
Nfat1 regulates adult articular chondrocyte function through its age-dependent expression mediated by epigenetic histone methylation.
Topics: Aging; Animals; Base Sequence; Cartilage, Articular; Chondrocytes; Chromatin Immunoprecipitation; Epigenesis, Genetic; Gene Knockdown Techniques; Histone Demethylases; Histones; Jumonji Domain-Containing Histone Demethylases; Lysine; Methylation; Mice; Molecular Sequence Data; NFATC Transcription Factors; Osteoarthritis; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Up-Regulation | 2011 |
Progressive methylation of ageing histones by Dot1 functions as a timer.
Topics: Aging; Cell Cycle; Chromatin; Gene Expression Regulation, Fungal; Histone-Lysine N-Methyltransferase; Histones; Methylation; Nuclear Proteins; Nucleosomes; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2011 |
Crosstalk between aging and the epigenome.
Topics: Aging; Animals; Caenorhabditis elegans; Chromatin; Epigenesis, Genetic; Histones; Humans; Methylation | 2012 |
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult | 2012 |
Dissecting the genomic complexity underlying medulloblastoma.
Topics: Aging; Amino Acid Sequence; beta Catenin; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Child; Chromatin; Chromosomes, Human; DEAD-box RNA Helicases; DNA Helicases; DNA-Binding Proteins; Genome, Human; Genomics; Hedgehog Proteins; High-Throughput Nucleotide Sequencing; Histone Demethylases; Humans; Medulloblastoma; Methylation; Mutation; Mutation Rate; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Patched Receptors; Patched-1 Receptor; Phosphoprotein Phosphatases; Polyploidy; Receptors, Cell Surface; Sequence Analysis, RNA; Signal Transduction; T-Box Domain Proteins; Transcription Factors; Wnt Proteins | 2012 |
Dietary folic acid intake differentially affects methionine metabolism markers and hippocampus morphology in aged rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Diet; Dietary Supplements; Folic Acid; Folic Acid Deficiency; Hippocampus; Hyperhomocysteinemia; Male; Methionine; Methylation; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine | 2013 |
Induction of aberrant trimethylation of histone H3 lysine 27 by inflammation in mouse colonic epithelial cells.
Topics: Aging; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Colitis; Colon; Death-Associated Protein Kinases; Dextran Sulfate; Epithelial Cells; Gene Expression; Histones; Intestinal Mucosa; Lysine; Male; Methylation; Mice; Mice, Inbred BALB C; Neoplasms | 2012 |
Stress-associated H3K4 methylation accumulates during postnatal development and aging of rhesus macaque brain.
Topics: Aging; Animals; Brain; Chromatin; Chromatin Immunoprecipitation; Enhancer Elements, Genetic; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genome; High-Throughput Nucleotide Sequencing; Histones; Humans; Macaca mulatta; Methylation; Promoter Regions, Genetic; Protein Methyltransferases; Stress, Physiological | 2012 |
Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development.
Topics: Acetylation; Aging; Animals; Cells, Cultured; DNA Methylation; Embryo, Mammalian; Embryonic Development; Gene Expression Regulation, Developmental; Histones; Methylation; Mice; Mice, Inbred ICR; Mice, Knockout; Receptor, Notch1; Retina; RNA, Messenger; Signal Transduction; SOXC Transcription Factors; Tissue Culture Techniques | 2013 |
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging.
Topics: Aging; Amino Acid Sequence; Animals; Cell Line; Chromatography, High Pressure Liquid; Histones; Humans; Lysine; Mass Spectrometry; Metalloendopeptidases; Methylation; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Serine Endopeptidases; Time Factors | 2002 |
S-methylated cysteines in human lens gamma S-crystallins.
Topics: Adult; Aged; Aged, 80 and over; Aging; Chymotrypsin; Cysteine; gamma-Crystallins; Humans; Infant, Newborn; Lens, Crystalline; Methylation; Middle Aged; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2002 |
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.
Topics: Adenosine Triphosphate; Aging; Animals; Blotting, Western; Cell Survival; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Lysine; Male; Methylation; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Oxygen; Oxygen Consumption; Peptides; Rats; Rats, Wistar; Stress, Physiological; Time Factors | 2003 |
Methylation and carbamylation of human gamma-crystallins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Child; Child, Preschool; gamma-Crystallins; Humans; Infant; Infant, Newborn; Lens, Crystalline; Methylation; Middle Aged; Molecular Sequence Data; Molecular Weight; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Trypsin | 2003 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins | 1963 |
Androgen receptor mRNA is inversely regulated by testosterone and estradiol in adult mouse brain.
Topics: Aging; Animals; Cerebral Cortex; Estradiol; Female; Gene Expression Regulation; Male; Methylation; Mice; Promoter Regions, Genetic; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone | 2004 |
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.
Topics: Adenocarcinoma; Aging; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; DNA Damage; Epigenesis, Genetic; Humans; Kruppel-Like Transcription Factors; Lung Neoplasms; Lymphoma; Methylation; Mice; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Sarcoma, Experimental; Sirtuin 1; Sirtuins; Soft Tissue Neoplasms; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination | 2006 |
A shared splice site?
Topics: Aged, 80 and over; Aging; Aging, Premature; Child; Histones; Humans; Lamin Type A; Methylation; Progeria; RNA Splice Sites; RNA Splicing | 2006 |
A new molecular model of cellular aging based on Werner syndrome.
Topics: Aging; Animals; Cellular Senescence; DNA Methylation; DNA Replication; Escherichia coli; Humans; Methylation; Methyltransferases; Models, Biological; Models, Molecular; Mutagenesis; Werner Syndrome | 2007 |
Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging.
Topics: Aging; Cell Membrane; Cytoplasm; G1 Phase; HeLa Cells; Humans; Lamin Type A; Lamin Type B; Methylation; Mitosis; Mutant Proteins; Nuclear Lamina; Progeria; Protein Prenylation; Protein Transport; Recombinant Fusion Proteins | 2007 |
11p15 imprinting center region 1 loss of methylation is a common and specific cause of typical Russell-Silver syndrome: clinical scoring system and epigenetic-phenotypic correlations.
Topics: Abnormalities, Multiple; Aging; Chromosomes, Human, Pair 7; DNA; Face; Female; Fetal Growth Retardation; Genomic Imprinting; Humans; Infant, Newborn; Infant, Small for Gestational Age; Insulin-Like Growth Factor II; Male; Methylation; Mutation; Phenotype; Syndrome | 2007 |
Post-translational modifications in the nuclear region of young, aged, and cataract human lenses.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Cataract; Chromatography, Liquid; Crystallins; Humans; Lens Nucleus, Crystalline; Methylation; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Tandem Mass Spectrometry | 2007 |
Growth-related changes of parameters of the methylation cycle and jejunal aminopeptidase M in the rat.
Topics: Aging; Animals; CD13 Antigens; Female; Folic Acid; Growth; Homocysteine; Jejunum; Methylation; Rats; Rats, Inbred Lew; Vitamin B 12 | 2008 |
The relationship of myelin basic protein (arginine) methyltransferase to myelination in mouse spinal cord.
Topics: Aging; Animals; Cytoplasm; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Kinetics; Methylation; Methyltransferases; Mice; Myelin Basic Protein; Myelin Sheath; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Spinal Cord | 1982 |
Changes in methylation pattern of albumin and alpha-fetoprotein genes in developing rat liver and neoplasia.
Topics: Aging; alpha-Fetoproteins; Animals; Cell Line; DNA; DNA Restriction Enzymes; Female; Genes; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Pregnancy; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Serum Albumin | 1983 |
DNA methylation in chicken brain and liver.
Topics: Aging; Animals; Base Sequence; Brain; Chickens; Chromatography, High Pressure Liquid; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Female; Liver; Methylation; Tissue Distribution | 1984 |
Effect of protein diet on age-dependent methylation of liver nuclear components of mice administered N-nitrosodimethylamine.
Topics: Aging; Animals; Carbon Radioisotopes; Cell Nucleus; Dietary Proteins; Dimethylnitrosamine; DNA; Kinetics; Liver; Male; Methylation; Mice; Nucleoproteins; RNA | 1984 |
Nicotinamide methylation. Tissue distribution, developmental and neoplastic changes.
Topics: Aging; Animals; Brain; Carcinoma, Ehrlich Tumor; Cell Line; Female; Kidney; Liver; Liver Neoplasms, Experimental; Methylation; Methyltransferases; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains; Sarcoma 180; Sarcoma, Yoshida; Tissue Distribution | 1984 |
Age dependent changes in the methylation of rat brain phospholipids.
Topics: Aging; Animals; Brain; Male; Methylation; Methyltransferases; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Synaptosomes | 1981 |
Integration of new endogenous mouse mammary tumor virus proviral DNA at common sites in the DNA of mammary tumors of C3Hf mice and hypomethylation of the endogenous mouse mammary tumor virus proviral DNA in C3Hf mammary tumors and spleens.
Topics: Aging; Animals; Base Sequence; DNA, Viral; Genes, Viral; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred C3H; Recombination, Genetic; Spleen | 1983 |
Characterization of DNA methylation in the rat.
Topics: 5-Methylcytosine; Aging; Animals; Base Composition; Base Sequence; Cell Differentiation; Cell Line; Cytosine; DNA; DNA Restriction Enzymes; Embryo, Mammalian; Kidney; Liver; Methylation; Organ Specificity; Rats; Rats, Inbred Strains | 1982 |
Methylation of the chicken vitellogenin gene: influence of estradiol administration.
Topics: Aging; Animals; Chickens; Cloning, Molecular; DNA Restriction Enzymes; Estradiol; Female; Genes; Lipoproteins; Liver; Male; Methylation; Nucleic Acid Hybridization; Vitellogenins | 1983 |
Developmental changes in DNA methylation around prostatic steroid-binding protein genes.
Topics: Aging; Androgen-Binding Protein; Animals; Carrier Proteins; DNA; DNA Restriction Enzymes; Genes; Male; Methylation; Molecular Weight; Prostate; Rats; Rats, Inbred Strains | 1983 |
Methylation and rearrangement of mouse intracisternal a particle genes in development, aging, and myeloma.
Topics: Aging; Animals; Base Sequence; DNA, Neoplasm; Gene Expression Regulation; Genes, Viral; Liver; Methylation; Mice; Neoplasms, Experimental; Plasmacytoma; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Retroviridae | 1983 |
Covalent modifications of chromosomal proteins during aging.
Topics: Acetylation; Aging; Animals; Brain; Cells, Cultured; Cerebral Cortex; Chemical Phenomena; Chemistry; Chromatin; Chromosomal Proteins, Non-Histone; DNA; Erythrocytes; Gene Expression Regulation; Histones; Humans; Liver; Methylation; Phosphorylation; Protein Conformation; Rats; Thymus Gland | 1983 |
New applications of urinary nucleoside markers.
Topics: Adult; Aging; Burkitt Lymphoma; Child; Child, Preschool; Female; Humans; Infant; Male; Methylation; Neoplasms; Nucleosides; Reference Values; RNA, Neoplasm; RNA, Transfer; Sex Factors | 1983 |
DNA methylation decreases in aging but not in immortal cells.
Topics: 5-Methylcytosine; Aging; Animals; Cell Division; Cell Line; Cricetinae; Cytosine; DNA; Fibroblasts; Humans; Mesocricetus; Methylation; Mice; Time Factors | 1983 |
Carcinogenesis and aging. II. Modifying effect of aging on metabolism of methyl(acetoxymethyl)nitrosamine and its interaction with DNA of various tissues in rats.
Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Intestinal Mucosa; Liver; Lung; Methylation; Rats; Uterus | 1983 |
[Age and changes in the effect of hydrocortisone and an antioxidant on DNA methylation in mice].
Topics: Aging; Animals; Antioxidants; Chemical Phenomena; Chemistry; DNA; DNA, Neoplasm; Female; Gestational Age; Hydrocortisone; Mammary Neoplasms, Experimental; Methylation; Mice; Nucleotides; Organ Specificity; Picolines | 1981 |
In vitro methylation of chromosomal proteins of the brain of rats of various ages & its modulation by epinephrine.
Topics: Aging; Animals; Brain; Chromosomal Proteins, Non-Histone; Epinephrine; Female; Histones; Methylation; Nerve Tissue Proteins; Rats | 1980 |
Methylation of chromosomal proteins and DNA of rat brain and its modulation by estradiol and calcium during aging.
Topics: Aging; Animals; Brain; Calcium; Chromosomal Proteins, Non-Histone; DNA; Estradiol; Female; Histones; Methylation; Rats; Rats, Inbred Strains | 1981 |
Cerebellar tRNA methyltransferases: a developmental study.
Topics: Aging; Animals; Cerebellum; Cytosine; Guanine; Kinetics; Male; Methylation; Purkinje Cells; Rats; tRNA Methyltransferases | 1980 |
Partial restoration of impaired alpha 1-adrenergic responsiveness in parotid cells of aged rats by S-adenosylmethionine treatment.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Animals; Fluorescence Polarization; Inositol 1,4,5-Trisphosphate; Male; Membrane Fluidity; Membrane Lipids; Methylation; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Viscosity | 1995 |
Folate deficiency inhibits pancreatic amylase secretion in rats.
Topics: Aging; Amino Acids; Amylases; Animals; Body Weight; Cholecystokinin; Folic Acid Deficiency; Male; Methylation; Pancreas; Rats; Rats, Sprague-Dawley | 1995 |
[Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor.
Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; beta-Galactosidase; Binding Sites; Cell Nucleus; DNA-Binding Proteins; Embryo, Mammalian; Enkephalin, Leucine; Enkephalins; Methylation; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Precursors; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substrate Specificity; Transfection | 1995 |
Developmental and hormonal regulation of DNA methyltransferase in the rat testis.
Topics: Aging; Animals; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Gene Expression; Hypophysectomy; Male; Methylation; Mice; Organ Specificity; Rats; Rats, Sprague-Dawley; RNA, Messenger; Testis; Testosterone | 1995 |
Effects of energy restriction on age-associated changes of DNA methylation in mouse liver.
Topics: Aging; Animals; Deoxycytidine; DNA; Energy Metabolism; Female; Genes, myc; Liver; Methylation; Mice; Mice, Inbred C3H; Restriction Mapping | 1993 |
Aging-related changes in IGF-II and c-fos gene expression in the rat brain.
Topics: Aging; Animals; Blotting, Northern; Blotting, Southern; Brain; DNA; DNA Probes; Gene Expression Regulation; Genes, fos; Insulin-Like Growth Factor II; Male; Methylation; Nucleic Acid Hybridization; Rats; Rats, Wistar; RNA | 1993 |
Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression.
Topics: Adult; Aging; Animals; Base Sequence; Binding Sites; DNA; Fetal Hemoglobin; Gene Expression Regulation; Globins; Hemoglobinopathies; Humans; Leukemia, Erythroblastic, Acute; Methylation; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Restriction Mapping; Sp1 Transcription Factor; Transfection; Tumor Cells, Cultured | 1993 |
Age-related increases in glial fibrillary acidic protein do not show proportionate changes in transcription rates or DNA methylation in the cerebral cortex and hippocampus of male rats.
Topics: Aging; Animals; Blotting, Northern; Cerebral Cortex; DNA; DNA Probes; Glial Fibrillary Acidic Protein; Hippocampus; Male; Methylation; Rats; Rats, Inbred BN; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1994 |
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon.
Topics: Aging; Base Sequence; Colon; Colonic Neoplasms; Colorectal Neoplasms; Gene Expression; Humans; Methylation; Oligodeoxyribonucleotides; Receptors, Estrogen | 1994 |
Clonality and X-inactivation patterns in hematopoietic cell populations detected by the highly informative M27 beta DNA probe.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aging; Base Sequence; Blotting, Southern; Child; Child, Preschool; Chronic Disease; Cloning, Molecular; DNA Primers; DNA Probes; Female; Hematopoiesis; Humans; Leukemia; Leukocytes; Lymphoma, Non-Hodgkin; Methylation; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Reference Values; Restriction Mapping; X Chromosome | 1994 |
High-performance liquid chromatographic analysis of methylation changes of CCGG sequence in brain and liver DNA of mice during pre- and postnatal development.
Topics: Aging; Animals; Animals, Newborn; Base Sequence; Brain; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; DNA; Liver; Methylation; Mice; Mice, Inbred C57BL | 1994 |
Mechanisms for methylation-mediated gene silencing and aging.
Topics: Aging; Animals; Binding Sites; Cellular Senescence; DNA; DNA Replication; Genes, Regulator; Humans; Methylation; Models, Genetic; Protein Binding | 1993 |
Comparison of the age- and tumor-associated changes in the c-myc gene methylation in mouse liver.
Topics: Aging; Animals; DNA; DNA, Neoplasm; Genes, myc; Liver; Liver Neoplasms, Experimental; Methylation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL | 1993 |
Prenylated protein methyltransferase of rat cerebellum is developmentally co-expressed with its substrates.
Topics: Aging; Animals; Animals, Newborn; Cerebellum; GTP-Binding Proteins; Methylation; Nerve Tissue Proteins; Protein Methyltransferases; Rats; S-Adenosylmethionine; Subcellular Fractions; Synaptosomes | 1993 |
Expression of DNA methyltransferase in LEC rats during hepatocarcinogenesis.
Topics: Aging; Animals; Base Sequence; DNA; Gene Expression Regulation, Enzymologic; Liver; Liver Neoplasms; Methylation; Methyltransferases; Molecular Sequence Data; Oligonucleotide Probes; Rats; RNA, Messenger | 1993 |
Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period.
Topics: Adult; Aging; Base Sequence; Blotting, Southern; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; DNA Probes; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Humans; Hydroxylation; Infant; Infant, Newborn; Liver; Methylation; Microsomes, Liver; Molecular Sequence Data; Nucleic Acid Hybridization; Oxidoreductases, N-Demethylating; Restriction Mapping; RNA, Messenger | 1996 |
Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carcinoma, Hepatocellular; Child; Child, Preschool; DNA; Female; Genes, fos; Humans; Infant; Infant, Newborn; Liver Neoplasms; Male; Methylation; Middle Aged | 1996 |
Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Artifacts; Base Sequence; Cell Lineage; Clone Cells; Dosage Compensation, Genetic; Female; Heterozygote; Humans; Infant, Newborn; Methylation; Middle Aged; Models, Biological; Molecular Sequence Data; Phosphoglycerate Kinase; Polymerase Chain Reaction; RNA, Long Noncoding; RNA, Untranslated; Transcription Factors | 1996 |
Age-related changes in carboxyl methylation of proteins in the kidney.
Topics: Aging; Animals; cdc42 GTP-Binding Protein; Cell Cycle Proteins; GTP-Binding Proteins; Guanine Nucleotides; Kidney Cortex; Male; Methylation; Microvilli; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Rats; Rats, Sprague-Dawley | 1996 |
Hydroxyl radical formation via iron-mediated Fenton chemistry is inhibited by methylated catechols.
Topics: Aging; Brain; Catechol O-Methyltransferase; Catecholamines; Catechols; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Hydroxyl Radical; In Vitro Techniques; Iron; Kinetics; Methylation; Models, Chemical; Neurodegenerative Diseases | 1998 |
Effect of age on the breath methylated alkane contour, a display of apparent new markers of oxidative stress.
Topics: Adolescent; Adult; Aged; Aging; Alkanes; Biomarkers; Breath Tests; Child; Cytochrome P-450 Enzyme System; Female; Humans; Male; Methylation; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Sex Characteristics | 2000 |
Folate status and age affect the accumulation of L-isoaspartyl residues in rat liver proteins.
Topics: Age Factors; Aging; Animals; Aspartic Acid; Folic Acid; Folic Acid Deficiency; Isoaspartic Acid; Liver; Male; Methylation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 2002 |
[Changes in DNA methylation in rat during ontogenesis and under effects of hydrocortisone].
Topics: Aging; Animals; Animals, Newborn; Brain; DNA; DNA (Cytosine-5-)-Methyltransferases; Embryo, Mammalian; Female; Hydrocortisone; Kinetics; Liver; Methylation; Methyltransferases; Pregnancy; Rats | 1979 |
Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions.
Topics: Aging; Animals; Female; Homocysteine; Liver; Methylation; Methyltransferases; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine | 1979 |
Effects of oestradiol on covalent modifications of chromosomal proteins and transcription of chromatin of the brain of rats of various ages.
Topics: Acetylation; Aging; Animals; Brain; Chromatin; Chromosomal Proteins, Non-Histone; Estradiol; Female; Histones; Methylation; Phosphorylation; Rats; Transcription, Genetic | 1979 |
Differences between transfer RNA methylase activity in human diploid fibroblasts during in vitro and in vivo aging.
Topics: Adult; Aged; Aging; Cell Line; Child; Fetus; Fibroblasts; Humans; Infant; Methylation; Skin; Time Factors; tRNA Methyltransferases | 1979 |
Ontogenetic changes in the content of methylated amino acids in rodent skeletal muscle.
Topics: Aging; Animals; Arginine; Cricetinae; Histidine; Lysine; Male; Methylation; Methylhistidines; Mice; Muscle Development; Muscles; Myosins; Rats | 1977 |
Temporal changes in histone acetylation.
Topics: Acetates; Acetylation; Aging; Animals; DNA Replication; Histones; Liver; Male; Methylation; Phosphorylation; Rats; Thymus Gland | 1978 |
[Tissue-specific decrease and change in the character of DNA methylation in cattle with aging].
Topics: Aging; Animals; Brain Chemistry; Cattle; Chemical Phenomena; Chemistry; Cytosine; DNA; Kidney; Liver; Lung; Methylation; Myocardium; Nucleotides; Organ Specificity; Spleen; Thymus Gland | 1978 |
[In vitro methylation of nuclear DNA from various organs of a rat: Tissue and age differences in acceptor ability of DNA].
Topics: Aging; Animals; Brain; Cell Nucleus; Culture Media; DNA; DNA (Cytosine-5-)-Methyltransferases; In Vitro Techniques; Kidney; Liver; Lung; Methylation; Methyltransferases; Rats; S-Adenosylmethionine; Spleen; Tritium | 1976 |
DNA modification mechanisms and gene activity during development.
Topics: Aging; Animals; Base Sequence; Binding Sites; Biological Clocks; Cell Differentiation; Cell Division; Chick Embryo; Clone Cells; DNA; DNA Replication; Enzyme Repression; Genes; Genes, Regulator; Genetic Code; Growth; Methylation; Methyltransferases; Models, Biological; Morphogenesis; Transcription, Genetic; Wings, Animal | 1975 |
Altered protein hypothesis of mammalian ageing processes-II. Discrimination ratio of methionine vs ethionine in the synthesis of ribosomal protein and RNA of C57BL/6J mouse liver.
Topics: Age Factors; Aging; Animals; Carbon Radioisotopes; Electrophoresis, Polyacrylamide Gel; Ethionine; Female; Liver; Methionine; Methionine Adenosyltransferase; Methionine-tRNA Ligase; Methylation; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Weight; Proteins; Ribosomal Proteins; RNA, Ribosomal; Tritium | 1975 |
Hepatic DNA methylation in young, middle-aged, and senescent rats: the effect of mitogen-induced cell proliferation.
Topics: Aging; Animals; Base Sequence; Cell Division; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Liver; Male; Methylation; Mitogens; Rats; Rats, Wistar | 1992 |
Phospholipid methylation and taurine content of synaptosomes from cerebral cortex of developing rat.
Topics: Aging; Animals; Cerebral Cortex; Male; Methionine; Methylation; Phospholipids; Rats; Synaptosomes; Taurine; Tritium | 1992 |
DNA methylation patterns of the gamma delta beta-globin genes in human fetal and adult erythroid tissues.
Topics: Adult; Aging; Autoradiography; Cytosine; DNA; DNA Restriction Enzymes; Erythroid Precursor Cells; Fetus; Gene Expression Regulation; Globins; Humans; Methylation; Nucleic Acid Hybridization; Promoter Regions, Genetic | 1992 |
Methylated cytosine level in human liver DNA does not decline in aging process.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Child; Child, Preschool; Deoxycytidine; DNA; Female; Humans; Infant; Infant, Newborn; Liver; Male; Methylation; Mice; Middle Aged; Rats; Species Specificity; Spleen | 1992 |
Methylation of DNA of the brain and liver of young and old rats.
Topics: Aging; Animals; Base Sequence; Brain; DNA; DNA Modification Methylases; Female; Liver; Methylation; Molecular Sequence Data; Rats; Rats, Inbred Strains | 1992 |
Methylation of CpG-island-containing genes in human sperm, fetal and adult tissues.
Topics: Aging; Blood; Dinucleoside Phosphates; Genes, myc; Genes, ras; Humans; Hypoxanthine Phosphoribosyltransferase; Insulin; Kidney; Male; Methylation; Muscles; Promoter Regions, Genetic; Spermatozoa | 1992 |
[The characteristic changes of immune function with aging--analysis of the mechanisms].
Topics: Adult; Aged; Aged, 80 and over; Aging; B-Lymphocytes; Humans; Interleukin-2; Interleukin-6; Lymphocyte Activation; Methylation; Oncogenes; Receptors, Interleukin-2; T-Lymphocytes | 1992 |
Stability of DNA methylation of X-chromosome genes during aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blotting, Southern; Carbohydrate Dehydrogenases; Child; Child, Preschool; Deoxyribonuclease BamHI; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Female; Gene Expression Regulation; Glucose Dehydrogenases; Humans; Male; Methylation; X Chromosome | 1990 |
Methylation changes in the apolipoprotein AI gene during embryonic development of the mouse.
Topics: Aging; Animals; Apolipoprotein A-I; Base Sequence; Crosses, Genetic; DNA; Embryonic and Fetal Development; Female; Humans; Male; Methylation; Mice; Mice, Inbred Strains; Mice, Transgenic; Molecular Sequence Data; Oligodeoxyribonucleotides; Organ Specificity; Ovum; Polymerase Chain Reaction; Restriction Mapping; Spermatozoa | 1991 |
Methylation of captopril in human liver, kidney and intestine.
Topics: Adult; Aged; Aging; Captopril; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Kidney; Kidney Cortex; Kidney Medulla; Liver; Male; Methylation; Methyltransferases; Microsomes; Microsomes, Liver; Middle Aged | 1991 |
Phenotype, ontogeny, and repertoire of CD4-CD8- T cell receptor alpha beta + thymocytes. Variable influence of self-antigens on T cell receptor V beta usage.
Topics: Aging; Animals; Antigens, Differentiation, T-Lymphocyte; Base Sequence; CD8 Antigens; Cell Differentiation; Cyclosporins; Immunophenotyping; Methylation; Mice; Mice, Inbred Strains; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocyte Subsets | 1991 |
Differential methylation of HMG proteins by dexamethasone in the liver of aging rats.
Topics: Aging; Animals; Chromatin; Dexamethasone; High Mobility Group Proteins; In Vitro Techniques; Liver; Male; Methylation; Rats; Rats, Wistar | 1991 |
Methylation, acetylation and phosphorylation of the bases of DNA of young and old rats.
Topics: Acetyl Coenzyme A; Acetylation; Adenosine Triphosphate; Aging; Animals; Brain; Cell Nucleus; DNA; Female; Liver; Methylation; Phosphorylation; Rats; Rats, Inbred Strains; S-Adenosylmethionine | 1991 |
Methylation status of cKi-ras and MHC genes in rat pituitary glands during aging and tumorigenesis.
Topics: Adenoma; Aging; Animals; DNA; DNA, Neoplasm; Female; Genes, MHC Class I; Genes, ras; Methylation; Pituitary Gland; Pituitary Neoplasms; Rats; Rats, Inbred Strains | 1991 |
DNA methylation and epigenetic inheritance.
Topics: Aging; Animals; Cells, Cultured; DNA; Embryonic and Fetal Development; Genetics; Methylation; Models, Genetic; Mutation; Phenotype | 1990 |
mRNA levels and methylation patterns of the tyrosine aminotransferase gene in aging inbred rats.
Topics: Aging; Animals; Blotting, Northern; Blotting, Southern; Gene Expression; Genes; Liver; Methylation; Rats; RNA, Messenger; Tyrosine Transaminase | 1990 |
Is DNA methylation of X chromosome genes stable during aging?
Topics: Aging; Dosage Compensation, Genetic; Humans; Methylation; X Chromosome | 1991 |
Effect of post-synthetic modifications of proteins on the binding of estrogen-receptor complex to uterine nuclei of aging rats.
Topics: Acetylation; Aging; Animals; Binding Sites; Cell Nucleus; Estradiol; Female; In Vitro Techniques; Methylation; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus | 1990 |
Quantitative changes in T cell DNA methylation occur during differentiation and ageing.
Topics: Adolescent; Aging; Blotting, Southern; Child; Child, Preschool; DNA; Gene Expression Regulation; Humans; Infant; Lymphocyte Activation; Methylation; T-Lymphocytes; Thymus Gland; Transcription, Genetic | 1990 |
Transient expression of type 2 chain in A-active hexaglycosylceramide of rat small intestine at weaning time. Demonstration by affinity chromatography and ceramide glycanase hydrolysis of A-active glycosphingolipids followed by gas chromatography and mass
Topics: Aging; Animals; Antibodies, Monoclonal; Ceramides; Chromatography, Affinity; Chromatography, Gas; Chromatography, Thin Layer; Duodenum; Female; Gas Chromatography-Mass Spectrometry; Glycosphingolipids; Ileum; Intestine, Small; Jejunum; Mass Spectrometry; Methylation; Muscle Development; Muscle, Smooth; Oligosaccharides; Rats; Rats, Inbred Strains; Weaning | 1990 |
Changes of DNA methylation level during pre- and postnatal periods in mice.
Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; DNA; Liver; Lung; Methylation; Mice; Postpartum Period; Spleen; Thymus Gland | 1990 |
Messenger RNA levels and methylation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging.
Topics: Actins; Aging; Animals; Brain; DNA; DNA Probes; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunoblotting; Liver; Methylation; Organ Specificity; Rats; Rats, Inbred Strains; RNA, Messenger; Spleen | 1990 |
Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3).
Topics: Adolescent; Adult; Aging; Antibodies, Monoclonal; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Female; Fetus; Gene Expression; Humans; Hydroxylation; Infant; Liver; Male; Methylation; Oxidation-Reduction; Tumor Cells, Cultured | 1990 |
DNase I hypersensitivity and methylation of the 5'-flanking region of the alpha 1-fetoprotein gene during developmental and glucocorticoid-induced repression of its activity in rat liver.
Topics: Aging; alpha-Fetoproteins; Animals; Brain; Cloning, Molecular; Deoxyribonuclease I; Dexamethasone; DNA Restriction Enzymes; Genes; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Methylation; Nucleotide Mapping; Rats; Rats, Inbred Strains; Transcription, Genetic | 1986 |
Studies on myelin-basic-protein methylation during mouse brain development.
Topics: Aging; Amino Acids; Animals; Brain; Electrophoresis, Polyacrylamide Gel; Leucine; Methionine; Methylation; Mice; Mice, Inbred Strains; Myelin Basic Protein | 1986 |
Methylation of repetitive DNA sequences in the brain during aging of the rat.
Topics: Aging; Animals; Brain; Deoxyribonuclease EcoRI; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Female; Methylation; Rats; Rats, Inbred Strains; Repetitive Sequences, Nucleic Acid | 1989 |
Pharmacologic induction of embryonic globin gene expression in adult avian erythroid cells.
Topics: Aging; Animals; Autoradiography; Butyrates; Chickens; Gene Expression Regulation; Globins; Methylation; Multigene Family; Nucleic Acid Hybridization; Reticulocytes; Ribonucleases; RNA | 1989 |
Age-dependent and tissue-specific changes of DNA methylation within and around the c-fos gene in mice.
Topics: Aging; Animals; Brain; DNA; Gene Expression Regulation; Liver; Methylation; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Restriction Mapping; Spleen | 1989 |
Possible organ and age-related epigenetic factors in Huntington's disease and colorectal carcinoma.
Topics: Aging; Animals; Chromosome Deletion; Colorectal Neoplasms; Gene Expression Regulation; Genes, Switch; Humans; Huntington Disease; Methylation; Mutation | 1989 |
Age-related demethylation of mouse satellite DNA is easily detectable by HPLC but not by restriction endonucleases.
Topics: Aging; Animals; Chromatography, High Pressure Liquid; DNA Restriction Enzymes; DNA, Satellite; Male; Methylation; Mice; Mice, Inbred C57BL | 1989 |
Endogenous virus genomes become hypomethylated tissue--specifically during aging process of C57BL mice.
Topics: Aging; Animals; Brain; DNA, Viral; Female; Liver; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred C57BL; Retroviridae; Spleen; Virus Activation | 1989 |
Analysis of chromatin of the brain of young and old rats by nick-translation.
Topics: Aging; Animals; Brain Chemistry; Chromatin; Deoxyribonuclease EcoRI; Deoxyribonuclease HpaII; Deoxyribonuclease I; DNA Restriction Enzymes; Male; Methylation; Nucleic Acid Conformation; Protein Biosynthesis; Protein Conformation; Rats | 1985 |
Synkaryons: surrogate erythroid cells for the analysis of human globin gene switching.
Topics: Aging; Animals; Cell Separation; Chromosomes, Human, Pair 11; Fetus; Flow Cytometry; Gene Expression Regulation; Globins; Heterozygote; Humans; Hybrid Cells; Leukemia, Erythroblastic, Acute; Methylation; Mice; Mutation; Phenotype; Tumor Cells, Cultured | 1989 |
Thyroid hormone-, carbohydrate, and age-dependent regulation of a methylation site in the hepatic S14 gene.
Topics: Aging; Animals; Chromosome Mapping; Dietary Carbohydrates; Gene Expression Regulation; Hypothyroidism; Liver; Male; Methylation; Rats; Rats, Inbred Strains; RNA, Messenger; Triiodothyronine | 1989 |
Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA.
Topics: 5-Methylcytosine; Adult; Aged; Aging; Cytosine; DNA; Genes; Humans; Lymphocytes; Methylation; Transcription, Genetic | 1989 |
Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice.
Topics: Aging; Animals; Blotting, Southern; DNA; Female; Liver; Methylation; Mice; Mice, Inbred C57BL; Organ Specificity; Proto-Oncogenes; RNA, Messenger; Spleen; Transcription, Genetic | 1989 |
Age-specific methylation of high-mobility-group proteins of the rat liver and its modulation by spermine and sodium butyrate.
Topics: Aging; Animals; Butyrates; Butyric Acid; Chromatin; High Mobility Group Proteins; Liver; Male; Methionine; Methylation; Rats; Rats, Inbred Strains; Spermine | 1989 |
Human DNA methylation: methylated DNA-binding protein, differentiation and cancer.
Topics: Aging; Cell Differentiation; DNA; DNA Restriction Enzymes; DNA-Binding Proteins; Female; Fetus; Humans; Methylation; Neoplasms; Pregnancy | 1985 |
Protein carboxyl methylation-demethylation system in developing rat livers.
Topics: Adrenocorticotropic Hormone; Aging; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Carboxylic Ester Hydrolases; Cell Nucleus; Cytosol; Kinetics; Liver; Methanol; Methylation; Microsomes, Liver; Mitochondria, Liver; Protein Methyltransferases; Protein O-Methyltransferase; Rats | 1985 |
Conformational changes in muscarinic receptors may produce diminished cholinergic neurotransmission and memory deficits in aged rats.
Topics: Acetylcholine; Aging; Animals; Brain; Hippocampus; Male; Memory; Methylation; Molecular Conformation; Phospholipids; Rats; Rats, Inbred F344; Receptors, Muscarinic; Synaptic Transmission | 1985 |
Methylation of the c-myc gene changes during aging process of mice.
Topics: Actins; Aging; Animals; Base Sequence; Brain; DNA Restriction Enzymes; Female; Liver; Methylation; Mice; Mice, Inbred C57BL; Proto-Oncogenes; Tetrahydrofolate Dehydrogenase | 1986 |
Reduced S-adenosylmethionine:protein-lysine N-methyltransferase activity (protein methylase III) in shiverer mutant mouse brain.
Topics: 5'-Nucleotidase; Aging; Amino Acids; Animals; Brain; Histone-Lysine N-Methyltransferase; Methylation; Mice; Mice, Neurologic Mutants; Myelin Sheath; Nucleotidases; Protein Methyltransferases; Protein O-Methyltransferase | 1987 |
Differential effects on the metabolism of dimethylnitrosamine and aflatoxin B1 by hepatic microsomes from senescent rats.
Topics: Aflatoxin B1; Aflatoxins; Aging; Animals; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; DNA; Glutathione Transferase; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Rats; Rats, Inbred Strains | 1986 |
DNA alkylation by nitrosobis-(2-oxopropyl)amine in rats of different ages.
Topics: Aging; Alkylation; Animals; DNA; Female; Kidney; Liver; Male; Methylation; Nitrosamines; Rats; Rats, Inbred F344 | 1988 |
[Effect of vitamin B12 on carnitine synthesis in the body of rats].
Topics: Aging; Animals; Carnitine; Liver; Male; Methylation; Rats; Vitamin B 12 | 1988 |
Protection of phosphoglycerate kinase against in vitro aging by selective cysteine methylation.
Topics: Aging; Animals; Cysteine; Kinetics; Mercaptoethanol; Methylation; Muscle Development; Muscles; Phosphoglycerate Kinase; Rats; Rats, Inbred F344; Reference Values | 1988 |
7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.
Topics: Aging; Animals; Cell Nucleus; Chromatography, High Pressure Liquid; DNA; DNA, Mitochondrial; Electrochemistry; Female; Guanine; Liver; Methylation; Mitochondria; Rats; Rats, Inbred Strains | 1988 |
Age-related changes of proliferative response, kinetics of expression of protooncogenes after the mitogenic stimulation and methylation level of the protooncogene in purified human lymphocyte subsets.
Topics: Aging; B-Lymphocytes; Ethers; Humans; Ionomycin; Methylation; Oncogenes; Proto-Oncogenes; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
An assessment of phospholipid methylation in sarcolemma and sarcoplasmic reticulum of the aging myocardium.
Topics: Aging; Animals; Methylation; Myocardium; Phospholipids; Rats; Rats, Inbred Strains; Sarcolemma; Sarcoplasmic Reticulum | 1988 |
Substrates of protein carboxyl methyltransferase: kinetics and mechanism of their formation.
Topics: Aging; Animals; Computer Graphics; Crystallins; Kinetics; Lens, Crystalline; Methylation; Models, Molecular; Protein Conformation; Protein Methyltransferases; Protein O-Methyltransferase; Protein Processing, Post-Translational; Substrate Specificity | 1988 |
The carboxylmethylation of membrane-bound proteins in the aging rat brain.
Topics: Aging; Animals; Brain; Kinetics; Male; Membrane Proteins; Methylation; Protein Methyltransferases; Protein O-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Synaptic Membranes | 1988 |
DNA methylation in aging of mice.
Topics: Aging; Animals; Base Composition; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA; Female; Liver; Male; Methylation; Mice; Mice, Inbred C57BL | 1987 |
Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells.
Topics: Aging; Animals; Animals, Newborn; Brain; Cell Line; DNA; DNA, Neoplasm; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Plasmacytoma; Repetitive Sequences, Nucleic Acid | 1986 |
Developmental changes in the activities of enzymes related to methyl group metabolism in sheep tissues.
Topics: Aging; Alcohol Oxidoreductases; Animals; Betaine-Homocysteine S-Methyltransferase; Kinetics; Liver; Methylation; Methyltransferases; Sheep | 1986 |
[DNA methylation and interaction with glucocorticoid receptor complexes in the rat liver].
Topics: 5-Methylcytosine; Adrenalectomy; Aging; Animals; Cytosine; DNA; Female; Hydrocortisone; Liver; Methylation; Rats; Receptors, Glucocorticoid | 1987 |
Genomic 5-methyldeoxycytidine decreases with age.
Topics: Aging; Animals; Brain Chemistry; Deoxycytidine; DNA; Humans; Intestinal Mucosa; Intestine, Small; Liver; Male; Methylation; Mice; Mice, Inbred C57BL; Peromyscus | 1987 |
[Characteristics of the carcinogenic action of methyl(acetoxymethyl)nitrosamine and DNA repair in rats of different ages].
Topics: Aging; Animals; Carcinogens; Dimethylnitrosamine; DNA; DNA Repair; Female; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1986 |
Sarcolemmal phospholipid N-methylation in genetically determined hamster cardiomyopathy.
Topics: Aging; Animals; Cardiomyopathies; Cricetinae; Heart; Kinetics; Mesocricetus; Methionine; Methylation; Myocardium; Phosphatidylethanolamines; Sarcolemma; Species Specificity; Tritium | 1987 |
Effect of age on DNA repair in carcinogenesis due to alkylating agents.
Topics: Age Factors; Aging; Alkylating Agents; Animals; Dimethylnitrosamine; DNA; DNA Repair; Liver; Methylation; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats | 1985 |
[DNA alkylation and repair in female rats subjected to methylnitrosourea exposure at different ages].
Topics: Aging; Alkylation; Animals; Carbon Radioisotopes; DNA; DNA Repair; Female; Methylation; Methylnitrosourea; Purines; Rats; Time Factors; Tissue Distribution | 1986 |
[Effect of age on carcinogenesis in female rats induced by methyl (acetoxymethyl) nitrosamine].
Topics: Aging; Alkylation; Animals; Carcinogens; Dimethylnitrosamine; DNA, Neoplasm; Male; Methylation; Neoplasms, Experimental; Purines; Rats; Time Factors; Tissue Distribution | 1985 |
Methionine-cysteine deficiency and alkylation of DNA in liver, kidney and lung of mice administered dimethylnitrosamine.
Topics: Aging; Alkylation; Animals; Cysteine; Diet; Dimethylnitrosamine; DNA; Kidney; Liver; Lung; Male; Methionine; Methylation; Mice; Purines | 1985 |
The significance of DNA methylation in cellular aging.
Topics: Aging; Animals; Cell Division; Cell Line; Diploidy; DNA; Fibroblasts; Humans; Kinetics; Lung; Methylation; Models, Biological; Mutation | 1985 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Feather keratin--analysis of subunit heterogeneity.
Topics: Agar; Aging; Amino Acids; Animals; Cellulose; Chickens; Chromatography, DEAE-Cellulose; Cross Reactions; Ducks; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Feathers; Immunodiffusion; Immunoelectrophoresis; Keratins; Methylation; Molecular Weight; Rabbits; Species Specificity; Turkeys | 1974 |
Biochemical characteristics of insect microsomes. N- and O-demethylation.
Topics: Abdomen; Age Factors; Aging; Aniline Compounds; Animals; Anisoles; Carbamates; Cattle; Cell Nucleus; Dealkylation; Demyelinating Diseases; Enzyme Activation; Female; Glucosephosphates; Houseflies; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methylation; Microsomes; Mitochondria; Mixed Function Oxygenases; NADP; Nitro Compounds; Nitrophenols; Osmolar Concentration; Oxidoreductases; Phosphates; Potassium; Potassium Chloride; Serum Albumin, Bovine; Sex Factors; Subcellular Fractions; Temperature | 1971 |
Changes in histone methylase activity of rat brain and liver with ageing.
Topics: Aging; Animals; Brain; Cell Nucleus; Histones; Liver; Methylation; Methyltransferases; Rats; S-Adenosylmethionine | 1974 |
In vivo methylation and turnover of rat brain histones.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Half-Life; Histones; Lysine; Male; Methionine; Methylation; Microsomes; Mitochondria; Nerve Tissue Proteins; Rats; Regression Analysis; Time Factors; Tritium | 1974 |
Aging effects on the liver aldolase of rabbits.
Topics: Aging; Amino Acids; Animals; Autoanalysis; Autoradiography; Carbon Radioisotopes; Chromatography, Gel; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Fructose-Bisphosphate Aldolase; Iodoacetates; Liver; Methylation; Rabbits | 1974 |
[Possibility of using heterologous DNA methylases for studying tissue and age characteristics of DNA structures].
Topics: Aging; Animals; Brain Chemistry; Cell-Free System; DNA; Escherichia coli; Liver; Methylation; Methyltransferases; Rabbits; Rats; Spleen | 1973 |
Aminoacylation and methylation of tRNA as a function of age in the rat.
Topics: Acylation; Aging; Amino Acids; Animals; Chromatography; In Vitro Techniques; Methods; Methylation; Rats; RNA, Transfer; Spleen | 1972 |
The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents.
Topics: Aging; Animals; Brain Chemistry; Cytosine; DNA; DNA, Mitochondrial; Genetics; Hydrocortisone; Kidney; Liver; Lung; Methylation; Myocardium; Rats; Spleen | 1973 |
Methylation of DNA in vivo by thymus, spleen, and liver of the rat.
Topics: Aging; Aminopterin; Animals; Animals, Newborn; Brucella abortus; Carbon Isotopes; Chromatography, Paper; DNA; Liver; Metabolism; Methionine; Methylation; Mitomycins; Nucleotides; Orotic Acid; Rats; Spleen; Thymus Gland; Time Factors; Tritium | 1970 |
Skeletal muscle lipids. I. Changes in fatty acid composition of lecithin in man during growth.
Topics: Abortion, Legal; Adolescent; Adult; Aging; Amino Alcohols; Child, Preschool; Chromatography, Gas; Chromatography, Thin Layer; Esters; Fatty Acids; Fatty Acids, Essential; Female; Gestational Age; Humans; Infant; Infant, Newborn; Inositol; Linoleic Acids; Lipid Metabolism; Male; Methylation; Middle Aged; Muscle Development; Muscles; Phosphatidylcholines; Phospholipids; Pregnancy | 1971 |
Variations in urinary steroid profiles after birth.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aging; Birth Weight; Chromatography, Gas; Computers; Ethers; Female; Gestational Age; Humans; Infant; Infant, Newborn; Male; Mass Spectrometry; Methods; Methylation; Pregnancy; Sex Factors; Silicon; Steroids; Time Factors | 1971 |
[Transmethylation processes in senile involution: a working hypothesis].
Topics: Adenine; Aging; Arteriosclerosis; Catecholamines; DNA; Humans; Lipoproteins; Methionine; Methylation; Methyltransferases; Phosphatidylcholines; Phospholipids; RNA; S-Adenosylmethionine; Vitamin B 12 | 1971 |
Age-dependency of various protein methylases.
Topics: Aging; Amines; Amino Acids; Animals; Brain; Brain Chemistry; Liver; Male; Methionine; Methods; Methylamines; Methylation; Methyltransferases; Proteins; Rats; Testis | 1971 |
Residues of total mercury and methylmercuric salts in lake trout as a function of age.
Topics: Aging; Animals; Mercury; Methylation; New York; Salmonidae; Water Pollution, Chemical | 1971 |