Page last updated: 2024-08-18

isomethyleugenol and Acute Promyelocytic Leukemia

isomethyleugenol has been researched along with Acute Promyelocytic Leukemia in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's11 (36.67)18.2507
2000's8 (26.67)29.6817
2010's9 (30.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Chen, H; Gao, C; Gao, Y; Guo, M; Guo, S; Hai, X; Lin, L; Wang, X; Wu, Z1
Gao, HY; He, XW; Shi, X; Yan, W; Yang, W1
Liu, Z; Sun, G; Wang, F; Wang, H; Wang, Y; Xi, S; Xu, Y; Yang, Y; Zheng, Q; Zheng, Y1
Doi, H; Ishii, H; Koyama, H; Sumi, K; Suzuki, M; Takashima-Hirano, M; Watanabe, C1
Bu, N; Cao, FL; Naranmandura, H; Wang, QQ; Zhang, YF; Zhou, J; Zhou, XY1
Bonaldi, T; Minucci, S; Noberini, R; Pruneri, G; Uggetti, A1
Beekman, R; Beverloo, HB; Palande, KK; Touw, IP; Valk, PJ; van der Meeren, LE1
Benoukraf, T; Bertucci, F; Calmels, B; Duprez, E; Ferrier, P; Grimwade, D; Mills, K; Saurin, AJ; Sieweke, M; Spicuglia, S; Tibéri, G; Vincent-Fabert, C; Zacarias-Cabeza, J1
Borutinskaite, VV; Navakauskiene, R; Savickiene, J; Treigyte, G1
Cao, F; Chen, B; Le, XC; Lu, X; Shen, S; Yuan, C; Zhou, J1
Chen, GQ; Chen, Z; Jing, Y; Styblo, M; Walton, F; Waxman, S; Weinberg, R; Zhou, L1
Gong, Z; Le, XC; Lu, X; Wang, Z; Zhou, J1
Au, WY; Chan, CH; Chim, CS; Fung, AT; Kwong, YL; Liang, RH; Ma, ES; Wong, KF1
Himeno, S; Kojima, C; Qu, W; Sakurai, T; Waalkes, MP1
Botrugno, OA; Carbone, R; Di Croce, L; Insinga, A; Minucci, S; Pelicci, PG; Ronzoni, S1
Chan, WW; Chim, CS; Kwong, YL; Pang, A1
Fukai, Y; Hirata, M; Ichikawa, N; Kaise, T; Kinoshita, K; Kobayashi, H; Ohta, S; Saitoh, H; Sakurai, T; Ueno, M1
He, ZX; Rao, H1
Feldhoff, PW; Harker, WG; Holguin, MH; Parr, RL; Slade, DL; Sullivan, DM1
Alimena, G; Arcese, W; Avvisati, G; D'Adamo, F; De Felice, L; Diverio, D; Lo Coco, F; Meloni, G; Montefusco, E; Pelicci, PG1
Samid, D1
Chakraborty, S; Nucifora, G; Senyuk, V1
Chang, ZF; Cheng, SM1
Ganser, A; Herrmann, F; Lübbert, M; Ludwig, WD; Mertelsmann, R; Oster, W1
Humphries, DE; Nicodemus, CF; Schiller, V; Stevens, RL1
Koeffler, HP; Lübbert, M; Miller, CW1
Koeffler, HP; Lübbert, M; Miller, CW; Prokocimer, M; Salser, W; Thomason, A1
Vilpo, JA; Vilpo, LM1
Aarbakke, J; Prytz, PS1
Hashimoto, Y; Himi, T; Kagechika, H; Kawachi, E; Shudo, K1

Reviews

1 review(s) available for isomethyleugenol and Acute Promyelocytic Leukemia

ArticleYear
Genetic lesions and perturbation of chromatin architecture: a road to cell transformation.
    Journal of cellular biochemistry, 2001, Volume: 82, Issue:2

    Topics: Acetylation; Amino Acid Motifs; Animals; Cell Transformation, Neoplastic; Chromatin; Chromosome Aberrations; CREB-Binding Protein; Dimerization; Gene Expression Regulation; Gene Targeting; Histones; Humans; Leukemia, Promyelocytic, Acute; Macromolecular Substances; Methylation; Mice; Models, Genetic; Multigene Family; Neoplasm Proteins; Nuclear Proteins; Nuclear Receptor Coactivator 2; Nucleosomes; Oncogene Proteins, Fusion; Phosphorylation; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Trans-Activators; Transcription Factors; Transcription, Genetic; Translocation, Genetic

2001

Trials

1 trial(s) available for isomethyleugenol and Acute Promyelocytic Leukemia

ArticleYear
Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.
    Chemical research in toxicology, 2004, Volume: 17, Issue:1

    Topics: Adult; Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; Arsenites; Cacodylic Acid; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Leukemia, Promyelocytic, Acute; Male; Methylation; Middle Aged; Oxidation-Reduction; Oxides

2004

Other Studies

28 other study(ies) available for isomethyleugenol and Acute Promyelocytic Leukemia

ArticleYear
Monomethylated arsenic was the Major methylated arsenic in Red blood cells of acute promyelocytic leukemia patients treated with arsenic trioxide.
    Toxicology letters, 2021, Sep-01, Volume: 347

    Topics: Adolescent; Adult; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Biotransformation; Cacodylic Acid; Child; Child, Preschool; Chromatography, High Pressure Liquid; Erythrocytes; Female; Hemoglobins; Humans; Infant; Infant, Newborn; Leukemia, Promyelocytic, Acute; Male; Methylation; Middle Aged; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Young Adult

2021
[Effects of EGCG on Proliferation, Cell Cycle and DAPK1 Gene Methylation of Acute Promyelocytic Leukemia NB4 Cell Line].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:5

    Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Death-Associated Protein Kinases; Humans; Leukemia, Promyelocytic, Acute; Methylation

2018
Arsenic methylation metabolism and liver injury of acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.
    Environmental toxicology, 2013, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Female; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Liver; Liver Function Tests; Male; Methylation; Middle Aged; Oxides; Sex Factors; Young Adult

2013
Synthesis of (11)C-labeled retinoic acid, [(11)C]ATRA, via an alkenylboron precursor by Pd(0)-mediated rapid C-[(11)C]methylation.
    Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15

    Topics: Alkenes; Antineoplastic Agents; Boron Compounds; Carbon Isotopes; Catalysis; Contrast Media; Humans; Leukemia, Promyelocytic, Acute; Methylation; Palladium; Positron-Emission Tomography; Tretinoin

2014
Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation.
    Oncotarget, 2015, Sep-22, Volume: 6, Issue:28

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Biotransformation; Cacodylic Acid; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Methylation; Nuclear Proteins; Oncogene Proteins, Fusion; Organometallic Compounds; Oxides; Promyelocytic Leukemia Protein; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Sumoylation; Time Factors; Transcription Factors; Tumor Suppressor Proteins

2015
Pathology Tissue-quantitative Mass Spectrometry Analysis to Profile Histone Post-translational Modification Patterns in Patient Samples.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:3

    Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Female; Histones; Humans; Leukemia, Promyelocytic, Acute; Methylation; Mice; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry; Tissue Fixation

2016
The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.
    PloS one, 2011, Jan-20, Volume: 6, Issue:1

    Topics: Antioxidants; Down-Regulation; Epigenesis, Genetic; Granulocyte Colony-Stimulating Factor; Histones; Humans; Leukemia, Promyelocytic, Acute; Lysine; Methylation; Peroxiredoxins; Transcription Initiation Site

2011
Characterisation of genome-wide PLZF/RARA target genes.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Acetylation; Binding Sites; Chromatin Immunoprecipitation; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genome-Wide Association Study; Histones; Humans; Kruppel-Like Transcription Factors; Leukemia, Promyelocytic, Acute; Methylation; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Promyelocytic Leukemia Zinc Finger Protein; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; U937 Cells

2011
Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells.
    Cellular & molecular biology letters, 2012, Volume: 17, Issue:4

    Topics: Acetylation; Cadherins; CD11b Antigen; Cell Differentiation; Cell Proliferation; CpG Islands; Cytidine; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; HL-60 Cells; Humans; Indoles; Leukemia, Promyelocytic, Acute; Methylation; Phthalimides; Promoter Regions, Genetic; Propionates; Tretinoin; Tryptophan

2012
Arsenic speciation in saliva of acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:6

    Topics: Adult; Antineoplastic Agents; Arsenates; Arsenic Trioxide; Arsenicals; Arsenites; Cacodylic Acid; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia, Promyelocytic, Acute; Male; Methylation; Middle Aged; Oxides; Saliva; Spectrophotometry, Atomic

2013
Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells.
    Cancer research, 2003, Apr-15, Volume: 63, Issue:8

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Differentiation; Coculture Techniques; Glutathione Peroxidase; Hematopoietic Stem Cells; Humans; Hydrogen Peroxide; K562 Cells; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lymphoma; Methylation; Neoplasm Proteins; Oncogene Proteins, Fusion; Oxides; Tumor Cells, Cultured

2003
Serial studies of methylation of CDKN2B and CDKN2A in relapsed acute promyelocytic leukaemia treated with arsenic trioxide.
    British journal of haematology, 2005, Volume: 131, Issue:5

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Humans; Leukemia, Promyelocytic, Acute; Methylation; Neoplasm, Residual; Oxides; Reverse Transcriptase Polymerase Chain Reaction

2005
Chronic exposure to methylated arsenicals stimulates arsenic excretion pathways and induces arsenic tolerance in rat liver cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 91, Issue:1

    Topics: Animals; Arsenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Glutathione Transferase; Leukemia, Promyelocytic, Acute; Liver; Methylation; Rats; Rats, Inbred F344

2006
Recruitment of the histone methyltransferase SUV39H1 and its role in the oncogenic properties of the leukemia-associated PML-retinoic acid receptor fusion protein.
    Molecular and cellular biology, 2006, Volume: 26, Issue:4

    Topics: Cell Differentiation; DNA Methylation; Gene Silencing; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Promyelocytic, Acute; Methylation; Methyltransferases; Models, Biological; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Promyelocytic Leukemia Protein; Protein Methyltransferases; Repressor Proteins; Transcription Factors; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; U937 Cells

2006
Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor.
    Leukemia, 2006, Volume: 20, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Multivariate Analysis; Prognosis; Recurrence; Remission Induction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Sensitivity and Specificity; Survival Rate; Tretinoin; Tumor Cells, Cultured

2006
Clinical pharmacokinetic study of arsenic trioxide in an acute promyelocytic leukemia (APL) patient: speciation of arsenic metabolites in serum and urine.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:5

    Topics: Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Chromatography, High Pressure Liquid; Drug Resistance, Neoplasm; Humans; Injections, Intravenous; Leukemia, Promyelocytic, Acute; Male; Methylation; Oxides; Seafood; Tretinoin

2006
The effect of 5-azacytidine (5-aza-CR) and its analogue on cell differentiation and DNA methylation of HL-60 cells.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1993, Volume: 36, Issue:4

    Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Decitabine; DNA-Cytosine Methylases; DNA-Directed RNA Polymerases; DNA, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Methylation; Tumor Cells, Cultured

1993
Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line.
    Cancer research, 1995, Apr-15, Volume: 55, Issue:8

    Topics: Base Sequence; Cell Line; DNA Primers; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Gene Expression; Humans; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Methylation; Mitoxantrone; Molecular Sequence Data; Molecular Weight; Polymerase Chain Reaction; Restriction Mapping; RNA, Messenger; Subcellular Fractions; Transcription, Genetic; Tumor Cells, Cultured

1995
Polyclonal hematopoietic reconstitution in leukemia patients at remission after suppression of specific gene rearrangements.
    Blood, 1993, Jul-15, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow Transplantation; Carrier Proteins; Child, Preschool; Combined Modality Therapy; DNA, Neoplasm; Female; Gene Rearrangement; Hematopoiesis; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Methylation; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Retinoic Acid; Remission Induction

1993
Re: Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.
    Journal of the National Cancer Institute, 1999, Mar-03, Volume: 91, Issue:5

    Topics: Antineoplastic Agents; DNA, Neoplasm; Drug Synergism; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leukemia, Promyelocytic, Acute; Methylation; Neovascularization, Pathologic; Phenylbutyrates; Transcription, Genetic; Tretinoin

1999
Methylation-sensitive protein-DNA interaction at the cell cycle regulatory domain of human thymidine kinase promoter.
    Biochemical and biophysical research communications, 1992, Nov-30, Volume: 189, Issue:1

    Topics: Base Sequence; Binding Sites; Blotting, Northern; Cell Cycle; Cell Line; Cell Nucleus; DNA, Neoplasm; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Methylation; Molecular Sequence Data; Nuclear Proteins; Poly A; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA; RNA, Messenger; Thymidine Kinase; Tumor Cells, Cultured

1992
A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias.
    Blood, 1992, Oct-15, Volume: 80, Issue:8

    Topics: Blotting, Northern; Blotting, Southern; DNA Probes; DNA, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methylation; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
The human serglycin gene. Nucleotide sequence and methylation pattern in human promyelocytic leukemia HL-60 cells and T-lymphoblast Molt-4 cells.
    The Journal of biological chemistry, 1992, Jul-05, Volume: 267, Issue:19

    Topics: Base Sequence; Blotting, Northern; Blotting, Southern; Cell Line; DNA; Humans; Introns; Leukemia, Promyelocytic, Acute; Methylation; Molecular Sequence Data; Proteoglycans; RNA; T-Lymphocytes; Tumor Cells, Cultured; Vesicular Transport Proteins

1992
Changes of DNA methylation and chromatin structure in the human myeloperoxidase gene during myeloid differentiation.
    Blood, 1991, Jul-15, Volume: 78, Issue:2

    Topics: Base Sequence; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Line; Chromatin; Cloning, Molecular; DNA; DNA, Neoplasm; Genes; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Lymphoma; Methylation; Peroxidase; Restriction Mapping

1991
Stable methylation patterns of MYC and other genes regulated during terminal myeloid differentiation.
    Leukemia, 1991, Volume: 5, Issue:7

    Topics: Blotting, Northern; Blotting, Southern; Cell Differentiation; Cell Line; Chromosome Mapping; DNA; DNA Restriction Enzymes; Ferritins; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Methylation; RNA, Messenger; RNA, Neoplasm

1991
Biochemical mechanisms by which reutilization of DNA 5-methylcytosine is prevented in human cells.
    Mutation research, 1991, Volume: 256, Issue:1

    Topics: 5-Methylcytosine; Cell Extracts; Cells, Cultured; Chromatography, Thin Layer; Cytosine; DCMP Deaminase; Deoxycytidine Monophosphate; DNA; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphocytes; Methylation; Nucleoside-Phosphate Kinase; Phosphorylation; Tetrahydrouridine; Tumor Cells, Cultured

1991
Differential cell cycle perturbation by transmethylation inhibitors.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Aminoglycosides; Anti-Bacterial Agents; Cell Cycle; Enzyme Inhibitors; Flow Cytometry; Humans; Hydrolases; Interphase; Kinetics; Leukemia, Promyelocytic, Acute; Methylation; Mitosis; Tubercidin; Tumor Cells, Cultured

1990
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:11

    Topics: Amides; Binding Sites; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Molecular Structure; Retinoids; Structure-Activity Relationship

1988