Page last updated: 2024-08-18

isomethyleugenol and Acute Myelogenous Leukemia

isomethyleugenol has been researched along with Acute Myelogenous Leukemia in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (12.38)	18.7374
1990's	14 (13.33)	18.2507
2000's	8 (7.62)	29.6817
2010's	40 (38.10)	24.3611
2020's	30 (28.57)	2.80

Authors

Authors	Studies
Gonskikh, Y; Liu, KF; Shen, H; Stoute, J	1
Göllner, S; Kienhöfer, M; Müller-Tidow, C; Pauli, C	1
Fu, HY; Shen, JZ; Zhang, F; Zhou, HR	1
Chen, Q; Lin, J; Qian, J; Shi, J; Yuan, Q; Zhang, L; Zhang, T; Zhang, W; Zhou, H; Zhou, J	1
Du, A; Gao, Y; Jiang, B; Wang, J; Wu, X; Zhang, P; Zhao, Q	1
Fang, K; Han, S; Han, Y; Qi, J; Tang, Y; Wang, H; Wu, D	1
Fu, Y; Huang, L; Huang, M; Liu, H; Shen, D; You, Y; Zhao, B; Zheng, Y	1
Gong, Y; Ouyang, X	1
Bai, X; Chen, X; Li, J; Li, Z; Wang, M; Wu, H; Wu, Y	1
Ali, AM; Salih, GF	1
Aroua, N; Baldus, C; Beckmann, R; Bornhäuser, M; Cheng, J; Fijalkowska, D; Frye, M; Göllner, S; Jeremias, I; Krijgsveld, J; Liu, Y; Lotze, M; Müller-Tidow, C; Oellerich, T; Pabst, C; Raffel, S; Rohde, C; Röllig, C; Sauer, T; Serve, H; Thiede, C; Trumpp, A; Wirth, AK; Yu, X; Yun, H; Zhou, F	1
Cai, X; Chen, M; Chen, S; Lu, X; Qin, W; Zeng, Z	1
Fang, ZH; Feng, WY; Zheng, SY	1
Bray, MR; Chan, KC; Chan, NN; Dang, CC; Dou, Z; Goyama, S; Huen, MS; Kwok, TH; Lam, W; Leung, AY; Leung, WY; Mak, TW; Man, CH; Ng, KL; Ng, TC; So, CWE; Wong, CC; Zeng, XY; Zheng, LC	1
Cai, M; Chen, Y; Hong, Y; Li, S; Liu, Y; Wu, X	1
Palm-Apergi, C	1
Gritsman, K	1
Audebert, S; Bertucci, F; Birnbaum, D; Calmels, B; Camoin, L; Chabannon, C; Chevalier, C; Duprez, E; Finetti, P; Garciaz, S; N'guyen Dasi, L; Platet, N; Pophillat, M; Poplineau, M; Récher, C; Vernerey, J; Vey, N	1
Gorshkov, V; Grinev, V; Helin, K; Hendrickson, RC; Jensen, ON; Kovalchuk, S; Lorenzini, E; Radzisheuskaya, A; Shliaha, PV; Shlyueva, D	1
Al-Kali, A; Bode, AM; Chen, C; Chi, YI; Dou, L; Gao, L; Gao, Y; Huang, H; Li, D; Li, Y; Litzow, MR; Liu, C; Liu, D; Liu, S; Liu, T; Marcucci, G; Pang, J; Shen, N; Shi, J; Singh, P; Wang, L; Wang, Q; Xu, Y; Yan, F; Yu, L; Zheng, D; Zhou, L	1
Baran, Y; Çekdemir, D; Engür, S; Hastar, N; Kiraz, Y; Koca, D; Ulu, GT	1
Kishtagari, A; Levine, RL; Viny, AD	1
An, J; Ko, M	1
Chen, TQ; Chen, YQ; Fang, K; Han, C; Huang, W; Luo, XQ; Pan, Q; Sun, LY; Sun, YM; Wang, D; Wang, WT; Yang, QQ; Zeng, ZC	1
Armstrong, SA; Olsen, SN	1
Asou, N; Benoukraf, T; Matsumura, T; Matsuoka, M; Muddineni, SSNA; Nakamura-Ishizu, A; Okuda, T; Osato, M; Sian, S; Suda, T; Tan, DQ; Tirado-Magallanes, R; Tokunaga, K; Wang, CQ	1
Bernt, KM; Bollig, MK; Chen, BR; Deshpande, AJ; Intlekofer, AM; Kingsley, MC; Libbrecht, C; Pastuer, T; Riedel, SS; Shank, T; Stabler, SP; Xie, HM	1
Chen, Y; Cheng, T; Cheng, X; Chu, Y; Guan, J; Guo, H; Li, M; Shi, D; Shi, J; Wang, B; Wang, X; Xue, C; Yuan, W	1
Hu, H; Muntean, AG; Peterson, LF; Ropa, J; Saha, N; Talpaz, M	1
Aspris, D; Tzelepis, K; Yankova, E	1
Chen, J; Qing, Y; Su, R	1
Barbosa, K; Bohlander, SK; Cox, KL; Deshpande, A; Deshpande, AJ; Khanal, S; Klein, BJ; Kutateladze, TG; Poirier, MG; Shi, X; Sinha, A; Tong, Q; Wen, H; Xuan, F; Zandian, M; Zhang, P; Zhang, Y	1
Kranc, KR	1
Chen, HB; Long, GF; Sun, H; Xu, JR; Yang, DH	1
Bai, J; Chen, H; He, A; Wang, X	1
Dirks, WG; Drexler, HG; Hu, Z; Macleod, RAF; Nagel, S; Pommerenke, C; Quentmeier, H; Wang, Z; Xu, X	1
Bhamra, A; Gil, V; Kwok, C; Petrie, K; Sbirkov, Y; Thompson, AJ; Zelent, A	1
Alvarado, Y; Boddu, P; Borthakur, G; Bose, P; Brandt, M; Cortes, J; Daver, N; DiNardo, CD; Garcia-Manero, G; Jabbour, EJ; Jorgensen, J; Kadia, T; Kantarjian, H; Konopleva, M; Naqvi, K; Pemmaraju, N; Pierce, S; Ravandi, F; Yilmaz, M	1
He, Z; Hu, Y; Huang, P; Li, Y; Liu, J; Liu, P; Lu, W; Wang, J; Wen, S	1
Alberich-Jorda, M; Fiser, K; Kramarzova, KS; Musilova, A; Rejlova, K; Starkova, J; Trka, J; Zaliova, M	1
Fujino, T; Goyama, S; Horikawa, S; Imoto, S; Inaba, T; Inoue, D; Kanai, A; Kawabata, KC; Kitamura, T; Kozuka-Hata, H; Li, Z; Matsui, H; Miyano, S; Nagase, R; Oyama, M; Saika, M; Sheridan, P; Xu, M; Yamaguchi, R; Yang, FC; Yokoyama, A; Zhang, YZ	1
Alachkar, H; Beckford, J; Du, Y; Wu, S	1
Fatica, A; Ianniello, Z	1
Chen, Q; Chen, S; Chen, Z; Li, J; Mi, JQ; Pandolfi, PP; Sun, H; Weng, X; Xu, J; Yan, X; Zhang, W; Zhao, C; Zhao, J; Zhu, J; Zhu, Y	1
Armstrong, SA; Cai, S; Dou, Y; Dressler, GR; Ge, K; Hess, JL; Jang, Y; Koche, R; Levine, RL; Mao, F; Miao, H; Phuc Khoa, LT; Sun, Y; Witkin, M; Xu, J; Zhou, B; Zou, Z	1
Cheng, Y; Kharas, MG; Vu, LP	1
Jamieson, C; Van Der Werf, I	1
Chen, J; Deng, Q; Dong, L; Dong, Z; Gan, J; Gao, Z; Han, L; Huang, Y; Jiang, H; Li, C; Lian, F; Mulloy, JC; Ni, T; Pan, G; Qian, Z; Sheng, Y; Su, R; Wang, Y; Wei, J; Wunderlich, M; Xu, H; Yang, CG; Zhang, N; Zhang, T; Zhang, ZS; Zhong, D; Zhou, H; Zhu, Z	1
Chou, WC; Hou, HA; Hsiao, M; Kuo, YY; Lee, MC; Tien, HF	1
Buchi, F; Gozzini, A; Masala, E; Rossi, A; Sanna, A; Santini, V; Spinelli, E; Valencia, A	1
Campbell, CA; Copeland, RA; Daigle, SR; Iwanowicz, D; Johnston, D; Klaus, CR; Moyer, MP; Olhava, EJ; Pollock, RM; Raimondi, A; Scott, MP; Smith, JJ	1
Armstrong, SA; Banka, D; Bernt, KM; Bradner, JE; Chang, J; Chen, CW; Chen, L; Cihan, A; Deshpande, A; Deshpande, AJ; Dias, S; Dzhekieva, L; Fazio, M; Ibáñez, G; Koche, R; Krivtsov, A; Luo, M; Roeder, RG; Sinha, AU; Zhu, N	1
Gao, L; Kang, HY; Li, MY; Wang, CB; Wang, LL; Wang, W; Wang, XR; Yu, L	1
Gu, H; Jia, X; Lee, KA; Levy, T; Ren, JM; Rikova, K; Silva, JC; Stokes, MP; Yang, V	1
Chen, XP; Jing, Y; Li, YH; Yu, L	1
Levine, RL; Pastore, F	1
Ahn, EY; Baddoo, MC; Butler, TW; Flemington, EK; Huang, G; Kim, JH; Lim, ST; Myers, RM; Park, EY; Park, H; Pauli-Behn, F; Stone, JK; Tan, M; Yan, X	1
Agger, K; Helin, K; Johansen, JV; Kooistra, SM; Miyagi, S; Pedersen, MT	1
Andreeff, M; Campbell, CT; Chevassut, T; Daigle, SR; Deng, L; Goodell, MA; Jeong, M; Kornblau, SM; Li, W; Luo, M; Rau, RE; Rodriguez, BA; Rogers, JH; Rosen, A; Song, Y; Sweet, S	1
Dietrich, D; Dietrich, J; Gevensleben, H; Goltz, D; Grünen, S; Kristiansen, G; Landsberg, J	1
Butler, JS; Coombes, KR; Dent, SY; Kornblau, SM; Qiu, YH; Yoo, SY; Zhang, N	1
Araujo-Cruz, MM; Bakkali, A; Bauser, M; Bochtler, T; Chaturvedi, A; Gabdoulline, R; Ganser, A; Geffers, R; Goparaju, R; Haegebarth, A; Herbst, L; Hess-Stumpp, H; Heuser, M; Ho, AD; Kaulfuss, S; Klett, L; Krämer, A; Neuhaus, R; Panknin, O; Pusch, S; Rehwinkel, H; Rippe, K; Sharma, A; Stichel, D; Struys, EA; Thol, F; Toschi, L; von Deimling, A; Zimmermann, K	1
Galm, O; Herman, JG; Jost, E; Osieka, R; Schmid, J; Schubert, C; Suzuki, H; Wilop, S	1
Cheung, N; So, CW; Yeung, J; Zeisig, BB	1
Armstrong, SA; Bracken, AP; Faber, J; Feng, Z; Jesneck, J; Krivtsov, AV; Kung, AL; Kutok, JL; Lemieux, ME; Silverman, LB; Sinha, AU; Vempati, S; Xia, X	1
Armstrong, SA; Feng, Z; Krivtsov, AV	1
Issa, JP; Oki, Y	1
Agrawal-Singh, S; Becker, A; Berdel, WE; Disselhoff, C; Dugas, M; Ehninger, G; Hascher, A; Isken, F; Klein, HU; Koschmieder, S; McClelland, M; Müller, FU; Müller-Tidow, C; Schlenke, P; Schmitz, W; Seidl, M; Serve, H; Thiede, C; Thoennissen, N; Tickenbrock, L; Tschanter, P; Wang, Y; zur Stadt, U	1
Baran, J; Bukowska-Straková, K; Papiez, MA; Wiczkowski, W	1
Chim, CS; Chung, LP; Jin, DY; Lam, WW; Li, GK; Liang, R; Loong, F; So, CC; Wong, KY	1
Campana, D; Cao, X; Crews, KR; Dolan, ME; Downing, J; Feldberg, T; Gandhi, V; Ghodke, Y; Hartford, C; Lamba, JK; Mitra, AK; Plunkett, W; Pounds, S; Raimondi, S; Ribeiro, RC; Rubnitz, JE	1
Altman, JK; Khan, I; Licht, JD	1
Abdel-Wahab, O; Adli, M; Aifantis, I; Bernstein, BE; Carroll, M; Chung, YR; Gao, J; Hricik, T; Jaffe, JD; Koche, R; LaFave, LM; Levine, RL; Melnick, A; Nimer, SD; Pandey, S; Park, CY; Patel, JP; Perna, F; Shih, AH; Taylor, JE; Zhao, X	1
Akria, L; Arad, A; Aviv, A; Braester, A; Dally, N; Filanovsky, K; Gafter-Gvili, A; Gatt, ME; Hellmann, I; Herishanu, Y; Herzog-Tzarfati, K; Leiba, R; Merkel, D; Mittelman, M; Nagler, A; Nemets, A; Ofran, Y; Ronson, A; Rouvio, O; Silbershatz, I; Tadmor, T; Vidal, L; Yeganeh, S	1
Di Mario, A; Guidi, F; Hohaus, S; Leone, G; Pagano, L; Scardocci, A; Voso, MT; Zini, G	1
Balkhi, MY; Behre, G; Behre, HM; Bohlander, SK; Christopeit, M; Geletu, M; Trivedi, AK	1
Baumann, H; Ghoshal Gupta, S; Wetzler, M	1
Christman, JK; Herzog, D; Mendelsohn, N; Schneiderman, N	1
Bouchard, J; Momparler, RL; Onetto, N; Rivard, GE	1
Kersten, W; Mach, M; Schneider, U	1
Hoffman, DR; Huberman, E	1
Cassileth, PA; Cooper, RA; Suholet, D	1
Dhodapkar, M; Grill, J; Lust, JA	1
Bradstock, KF; Kennedy, BG; Sewell, WA; Tschuchnigg, M	1
Holmes, EH; Hu, J; Macher, BA; Stults, CL	1
Kawakubo, K; Kimura, N; Nakazawa, S; Ohyashiki, JH; Ohyashiki, K; Tauchi, T; Toyama, K	2
Bessho, M; Boyd, Y; Hirashima, K; Jinnai, I; Murohashi, I; Nagai, K; Tomonaga, M; Toyoda, A; Yoshida, S	1
Breit, TM; van Dongen, JJ; Wolvers-Tettero, IL	1
Baylin, SB; Herman, JG; Jen, J; Merlo, A	1
Chim, CS; Kwong, YL; Liang, R; Tam, CY	1
Buckley, JD	1
Ganser, A; Herrmann, F; Lübbert, M; Ludwig, WD; Mertelsmann, R; Oster, W	1
Gale, RE; Linch, DC; Wheadon, H	1
Alhonen, L; Hämäläinen, E; Heinonen, K; Hiltunen, H; Jänne, J; Wahlfors, J	1
Baylin, SB; Benson, J; Evatt, BL; Fukuhara, T; Hooper, WC; Olson, AC; Pruckler, J; Vogler, WR	1
Brunning, RD; Goldfarb, AN; Litz, CE; Strickler, JG	1
Bouchard, J; Momparler, RL; Samson, J	1
Cheng, YC; Degraw, JI; Dutschman, GE; Nair, MG; Sirotnak, FM; Ueda, T	1
Boggs, BA; Chinault, AC; McCredie, KB; Spitzer, G; Stass, SA; Yoffe, G	1
Wong, T; Wu, MC; Yunis, AA; Ziboh, VA	1
Cohen, MB; Glazer, RI; Hartman, KD; Knode, MC; Linevsky, J	1
Grosso, LE; Pitot, HC	1
Andreoli, A; Mauri, C; Torelli, GM; Torelli, UL	1
Griffin, AC; Saunders, GF; Shirakawa, S	1

Reviews

14 review(s) available for isomethyleugenol and Acute Myelogenous Leukemia

Article	Year
Epitranscriptomic modifications in acute myeloid leukemia: m Biological chemistry, 2021, 11-25, Volume: 402, Issue:12 Topics: Core Binding Factor Alpha 2 Subunit; Humans; Leukemia, Myeloid, Acute; Methylation	2021
Recent Advances of m6A Demethylases Inhibitors and Their Biological Functions in Human Diseases. International journal of molecular sciences, 2022, May-22, Volume: 23, Issue:10 Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; RNA; RNA, Messenger	2022
One Stone, Two Birds: N6-Methyladenosine RNA Modification in Leukemia Stem Cells and the Tumor Immune Microenvironment in Acute Myeloid Leukemia. Frontiers in immunology, 2022, Volume: 13 Topics: Adenosine; Humans; Leukemia, Myeloid, Acute; Methylation; RNA; Stem Cells; Tumor Microenvironment	2022
[Research Progress of m6A Demethylase FTO and Its Inhibitors in Acute Myeloid Leukemia --Review]. Zhongguo shi yan xue ye xue za zhi, 2023, Volume: 31, Issue:3 Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Leukemia, Myeloid, Acute; Methylation; Prognosis	2023
Driver mutations in acute myeloid leukemia. Current opinion in hematology, 2020, Volume: 27, Issue:2 Topics: Epigenomics; Humans; Leukemia, Myeloid, Acute; Methylation; Mutation; Transcription Factors	2020
The N6-methyladenosine RNA modification in acute myeloid leukemia. Current opinion in hematology, 2021, 03-01, Volume: 28, Issue:2 Topics: Adenosine; Animals; Biomarkers; Disease Management; Disease Susceptibility; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; RNA	2021
RNA modifications in hematopoietic malignancies: a new research frontier. Blood, 2021, 08-26, Volume: 138, Issue:8 Topics: Adenosine; Hematologic Neoplasms; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Methylation; RNA Processing, Post-Transcriptional; RNA, Neoplasm	2021
MicroRNA: an important regulator in acute myeloid leukemia. Cell biology international, 2017, Volume: 41, Issue:9 Topics: Animals; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; MicroRNAs; RNA Processing, Post-Transcriptional	2017
N6-Methyladenosine Role in Acute Myeloid Leukaemia. International journal of molecular sciences, 2018, Aug-09, Volume: 19, Issue:8 Topics: Adenosine; DNA; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; RNA Processing, Post-Transcriptional; RNA, Messenger	2018
The Biology of m Cancer discovery, 2019, Volume: 9, Issue:1 Topics: Animals; Cell Differentiation; Gene Expression Regulation, Neoplastic; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Methylation; RNA, Messenger	2019
[Markers for Predicting Response to Hypomethylating Agents in MDS and AML Patients]. Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:6 Topics: Biomarkers, Tumor; Bone Marrow; Humans; Leukemia, Myeloid, Acute; Methylation; Myelodysplastic Syndromes	2015
Epigenetic regulators and their impact on therapy in acute myeloid leukemia. Haematologica, 2016, Volume: 101, Issue:3 Topics: Acetylation; Antimetabolites, Antineoplastic; Clinical Trials as Topic; DNA, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Molecular Targeted Therapy; Neoplasm Proteins; Signal Transduction	2016
Epigenetic mechanisms in AML - a target for therapy. Cancer treatment and research, 2010, Volume: 145 Topics: Acetylation; Antimetabolites, Antineoplastic; Antineoplastic Agents; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Delivery Systems; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Neoplasm Proteins; Protein Processing, Post-Translational	2010
Epigenetic regulation of signal transducer and activator of transcription 3 in acute myeloid leukemia. Leukemia research, 2008, Volume: 32, Issue:7 Topics: Epigenesis, Genetic; Humans; Leukemia, Myeloid, Acute; Methylation; Signal Transduction; STAT3 Transcription Factor	2008

Other Studies

91 other study(ies) available for isomethyleugenol and Acute Myelogenous Leukemia

Article	Year
Human DIMT1 generates N The Journal of biological chemistry, 2021, Volume: 297, Issue:4 Topics: Amino Acid Substitution; HEK293 Cells; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mutation, Missense; Neoplasm Proteins; RNA Processing, Post-Transcriptional; RNA, Neoplasm	2021
Genistein-induced Anticancer Effects on Acute Leukemia Cells Involve the Regulation of Wnt Signaling Pathway Through H4K20me1 Rather Than DNA Demethylation. Current medical science, 2021, Volume: 41, Issue:5 Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Demethylation; Gene Expression Regulation, Neoplastic; Genistein; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Phosphorylation; Sequence Analysis, DNA; Up-Regulation; Wnt Signaling Pathway	2021
Expression characteristic of Bioengineered, 2021, Volume: 12, Issue:2 Topics: Adolescent; Adult; B7 Antigens; Case-Control Studies; Cell Line, Tumor; Gene Expression Regulation, Leukemic; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Membrane Proteins; Methylation; Middle Aged; Multivariate Analysis; Protein Isoforms; RNA, Messenger; ROC Curve; Treatment Outcome; Young Adult	2021
m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Acute Myeloid Leukemia. Frontiers in immunology, 2021, Volume: 12 Topics: Adenosine; B7-H1 Antigen; Biomarkers, Tumor; Case-Control Studies; Databases, Genetic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Programmed Cell Death 1 Ligand 2 Protein; RNA Processing, Post-Transcriptional; RNA, Neoplasm; Signal Transduction; Tumor Microenvironment	2021
Characterization of m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration in acute myeloid leukemia. Cancer medicine, 2022, Volume: 11, Issue:5 Topics: Epigenesis, Genetic; Humans; Leukemia, Myeloid, Acute; Methylation; Prognosis; Tumor Microenvironment	2022
MicroRNA-1306-5p Regulates the METTL14-Guided m6A Methylation to Repress Acute Myeloid Leukemia. Computational and mathematical methods in medicine, 2022, Volume: 2022 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Ki-67 Antigen; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice; MicroRNAs	2022
Identification of three novel DNMT3A mutations with compromising methylation capacity in human acute myeloid leukaemia. Molecular biology reports, 2022, Volume: 49, Issue:12 Topics: DNA Methylation; DNA Methyltransferase 3A; DNA Modification Methylases; Humans; Leukemia, Myeloid, Acute; Methylation; Middle Aged; Mutation; Neoplasm Recurrence, Local	2022
A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer discovery, 2023, 02-06, Volume: 13, Issue:2 Topics: Animals; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Neoplastic Stem Cells; Phenotype; Ribosomes; RNA, Ribosomal	2023
A novel prognostic model of methylation-associated genes in acute myeloid leukemia. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023, Volume: 25, Issue:6 Topics: Databases, Factual; Humans; Leukemia, Myeloid, Acute; Methylation; Multivariate Analysis; Prognosis	2023
Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML. Blood, 2023, Dec-07, Volume: 142, Issue:23 Topics: Animals; Histones; Immunity; Leukemia, Myeloid, Acute; Methylation; Mice; Mutation; Nucleotidyltransferases; Polyploidy; Tumor Suppressor Protein p53	2023
m5C methylation modification guides the prognostic value and immune landscapes in acute myeloid leukemia. Aging, 2023, 09-25, Volume: 15, Issue:18 Topics: 5-Methylcytosine; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Methylation; Prognosis; Tumor Microenvironment	2023
PLK4, a potential target against AML. Blood, 2023, Dec-07, Volume: 142, Issue:23 Topics: Histones; Humans; Immunity; Leukemia, Myeloid, Acute; Methylation; Nucleotidyltransferases; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53	2023
FLT3-ITD gets by with a little help from PRMT1. Blood, 2019, 08-08, Volume: 134, Issue:6 Topics: Arginine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mutation; Protein-Arginine N-Methyltransferases; Repressor Proteins	2019
Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation. Clinical epigenetics, 2019, 10-12, Volume: 11, Issue:1 Topics: Adult; Aged; Cell Differentiation; Cell Line, Tumor; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genetic Loci; Histones; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Prognosis; Survival Analysis; Young Adult	2019
PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Nature structural & molecular biology, 2019, Volume: 26, Issue:11 Topics: Animals; Antineoplastic Agents; Arginine; Catalysis; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Molecular Targeted Therapy; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oncogene Proteins, Fusion; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteomics; RNA Splicing; Serine-Arginine Splicing Factors	2019
Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia. Nature communications, 2019, 11-07, Volume: 10, Issue:1 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 2 Subunit; Gene Knockdown Techniques; Humans; Jurkat Cells; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Oncogene Proteins, Fusion; Polycomb Repressive Complex 2; Prognosis; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; THP-1 Cells	2019
Therapeutic Potentials of Inhibition of Jumonji C Domain-containing Demethylases in Acute Myeloid Leukemia Turkish journal of haematology : official journal of Turkish Society of Haematology, 2020, 02-20, Volume: 37, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Caspase 3; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Matrix Metalloproteinases; Membrane Potential, Mitochondrial; Methylation; Molecular Targeted Therapy; Protein Interaction Domains and Motifs	2020
Decoding ribosomes to keep growing (in AML). Blood, 2020, 06-04, Volume: 135, Issue:23 Topics: Cell Proliferation; Humans; Leukemia, Myeloid, Acute; Methylation; Protein Biosynthesis; Ribosomes; RNA, Ribosomal, 18S	2020
The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia. Journal of hematology & oncology, 2020, 06-17, Volume: 13, Issue:1 Topics: Animals; Cell Self Renewal; Child, Preschool; Female; Gene Expression Regulation, Leukemic; Genetic Vectors; Heterografts; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Infant; Leukemia, Myeloid, Acute; Lysine; Lysosomal Membrane Proteins; Male; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA Interference; RNA, Antisense; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Specific Pathogen-Free Organisms; Tumor Cells, Cultured; Tumor Stem Cell Assay	2020
It's Not What You Say But How You Say It: Targeting RNA Methylation in AML. Molecular cell, 2020, 06-18, Volume: 78, Issue:6 Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Immune Evasion; Leukemia, Myeloid, Acute; Methylation; Neoplastic Stem Cells; RNA	2020
Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia. Blood, 2020, 10-22, Volume: 136, Issue:17 Topics: Animals; Apoptosis; Cell Survival; Core Binding Factor Alpha 2 Subunit; Family; Female; Genetic Predisposition to Disease; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mutation, Missense; Myelodysplastic Syndromes; Pedigree; Protein Processing, Post-Translational	2020
Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML. Blood advances, 2020, 07-14, Volume: 4, Issue:13 Topics: Gene Rearrangement; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes	2020
SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia. Oncogene, 2020, Volume: 39, Issue:50 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Repressor Proteins; Transcription, Genetic	2020
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation. Haematologica, 2020, 09-01, Volume: 105, Issue:9 Topics: Animals; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion	2020
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations. Nature communications, 2021, 07-05, Volume: 12, Issue:1 Topics: Acute Disease; Animals; Carcinogenesis; Cell Transformation, Neoplastic; Chromatin; HEK293 Cells; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Models, Molecular; Monomeric Clathrin Assembly Proteins; Nucleosomes; Protein Conformation; Transcription Factors; Translocation, Genetic	2021
The essential reading list for AML: the m6A transcripts. Blood, 2021, 07-08, Volume: 138, Issue:1 Topics: Humans; Leukemia, Myeloid, Acute; Methylation; Reading; RNA, Messenger	2021
[Establishment and validation of prognosis predictive model using m Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2021, Aug-06, Volume: 55, Issue:8 Topics: Child; Cohort Studies; Humans; Leukemia, Myeloid, Acute; Methylation; RNA; RNA Helicases	2021
KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia. Leukemia & lymphoma, 2018, Volume: 59, Issue:1 Topics: Cell Line, Tumor; Gene Expression Regulation, Leukemic; Histones; Homeodomain Proteins; Humans; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Response Elements; Transcription Factors; Translocation, Genetic; Tretinoin	2018
Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase. International journal of molecular sciences, 2017, Jul-05, Volume: 18, Issue:7 Topics: Amino Acid Sequence; Carrier Proteins; Cell Line, Tumor; Computational Biology; Enhancer of Zeste Homolog 2 Protein; Gene Ontology; Histones; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mass Spectrometry; Methylation; Models, Molecular; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Interaction Maps; Workflow	2017
Achievement of a negative minimal residual disease state after hypomethylating agent therapy in older patients with AML reduces the risk of relapse. Leukemia, 2018, Volume: 32, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Prognosis; Recurrence; Risk	2018
Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo. Cancer letters, 2018, 01-28, Volume: 413 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histone Demethylases; Histones; HL-60 Cells; Humans; Hydrazines; Leukemia, Myeloid, Acute; Methylation; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Morpholines; Proto-Oncogene Proteins c-bcl-2; Pyridones; Sulfonamides; Time Factors; Tumor Cells, Cultured; Up-Regulation; Xenograft Model Antitumor Assays	2018
Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation. Epigenetics, 2018, Volume: 13, Issue:1 Topics: Benzazepines; Cell Differentiation; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Genes, Homeobox; Histone Demethylases; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Nuclear Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Pyrimidines; Tretinoin	2018
A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies. Leukemia, 2018, Volume: 32, Issue:6 Topics: Animals; Cell Differentiation; Female; HEK293 Cells; Histones; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Inbred C57BL; Myelodysplastic Syndromes; N-Acetylglucosaminyltransferases; Protein Stability; Repressor Proteins; Tumor Suppressor Proteins	2018
Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia. Journal of translational medicine, 2018, 06-20, Volume: 16, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Multivariate Analysis; Mutation; RNA, Messenger; Treatment Outcome; Up-Regulation; Vimentin; Young Adult	2018
Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival. Theranostics, 2018, Volume: 8, Issue:16 Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Gene Expression Profiling; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice, Transgenic; Myeloid Cells; Nuclear Proteins; Nucleophosmin; Protein Processing, Post-Translational; Proto-Oncogene Proteins	2018
HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis. Cancer cell, 2018, 10-08, Volume: 34, Issue:4 Topics: Animals; Cell Transformation, Neoplastic; Enhancer Elements, Genetic; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Promoter Regions, Genetic	2018
The Yin and Yang of RNA Methylation: An Imbalance of Erasers Enhances Sensitivity to FTO Demethylase Small-Molecule Targeting in Leukemia Stem Cells. Cancer cell, 2019, 04-15, Volume: 35, Issue:4 Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes; RNA; Stem Cells	2019
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer cell, 2019, 04-15, Volume: 35, Issue:4 Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Methylation; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Transgenic; Molecular Targeted Therapy; Protein Conformation; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; U937 Cells; Xenograft Model Antitumor Assays	2019
Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells. Journal of leukocyte biology, 2014, Volume: 95, Issue:1 Topics: Apoptosis; Cell Line, Tumor; DNA-Binding Proteins; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Piperazines; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; RNA Interference; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation	2014
Redistribution of H3K27me3 and acetylated histone H4 upon exposure to azacitidine and decitabine results in de-repression of the AML1/ETO target gene IL3. Epigenetics, 2014, Volume: 9, Issue:3 Topics: Acetylation; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; Chromatin Assembly and Disassembly; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA Modification Methylases; Gene Silencing; Histones; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Methylation; Promoter Regions, Genetic; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Transcription Factors	2014
DOT1L inhibitor EPZ-5676 displays synergistic antiproliferative activity in combination with standard of care drugs and hypomethylating agents in MLL-rearranged leukemia cells. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:3 Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Growth Inhibitors; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases	2014
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer cell, 2014, Dec-08, Volume: 26, Issue:6 Topics: Adenosine; Animals; Bone Marrow Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasms, Experimental; Nuclear Pore Complex Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Phenylurea Compounds; Transcription Factors	2014
[Clinical Implications on ZO-1 Gene Methylation in Myelodysplastic Syndrome Progression]. Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:3 Topics: Bone Marrow; Disease Progression; DNA Methylation; Humans; Leukemia, Myeloid, Acute; Methylation; Myelodysplastic Syndromes; Polymerase Chain Reaction; Zonula Occludens-1 Protein	2015
Quantitative Profiling of Post-translational Modifications by Immunoaffinity Enrichment and LC-MS/MS in Cancer Serum without Immunodepletion. Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:2 Topics: Acetylation; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatography, Liquid; Female; Humans; Leukemia, Myeloid, Acute; Methylation; Neoplasm Proteins; Protein Processing, Post-Translational; Proteomics; Tandem Mass Spectrometry	2016
SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes. Molecular cell, 2016, Mar-17, Volume: 61, Issue:6 Topics: Alternative Splicing; Cell Line, Tumor; Chromatin; DNA-Binding Proteins; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Methylation; Minor Histocompatibility Antigens; Myeloid-Lymphoid Leukemia Protein; Protein Binding; Protein Isoforms; Proto-Oncogene Proteins; Transcription, Genetic	2016
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells. Genes & development, 2016, 06-01, Volume: 30, Issue:11 Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Interleukin-3 Receptor alpha Subunit; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Methylation; Mice; Mice, Knockout; Protein Binding; Tamoxifen	2016
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood, 2016, 08-18, Volume: 128, Issue:7 Topics: Adenosine; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid, Acute; Lysine; Methylation; Methyltransferases; Mice, Inbred C57BL; Molecular Targeted Therapy; Mutation; Phenylurea Compounds; Rats; Time Factors; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays	2016
PD-L1 (CD274) promoter methylation predicts survival in patients with acute myeloid leukemia. Leukemia, 2017, Volume: 31, Issue:3 Topics: B7-H1 Antigen; Epigenesis, Genetic; Female; Humans; Immunity, Innate; Inflammation; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Promoter Regions, Genetic; T-Lymphocytes; Up-Regulation	2017
Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia. Leukemia & lymphoma, 2017, Volume: 58, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Epigenesis, Genetic; Female; fms-Like Tyrosine Kinase 3; Gene Expression; Gene Expression Profiling; Histones; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Prognosis; Protein Processing, Post-Translational; Transcription Factors; Young Adult	2017
Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo. Leukemia, 2017, Volume: 31, Issue:10 Topics: Aniline Compounds; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Glutarates; Histone Code; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Methylation; Mice; Molecular Targeted Therapy; Mutation; Mutation, Missense; Myeloid Cells; Myelopoiesis; Neoplasm Proteins; Neoplastic Stem Cells; Point Mutation; Protein Processing, Post-Translational; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays	2017
Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia. British journal of haematology, 2008, Volume: 142, Issue:5 Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; CpG Islands; Epigenesis, Genetic; Eye Proteins; Female; Humans; Intercellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Male; Membrane Proteins; Methylation; Middle Aged; Polymerase Chain Reaction; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Wnt Proteins	2008
Reconstructing the disease model and epigenetic networks for MLL-AF4 leukemia. Cancer cell, 2008, Nov-04, Volume: 14, Issue:5 Topics: Animals; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2008
H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer cell, 2008, Nov-04, Volume: 14, Issue:5 Topics: Animals; Biomarkers, Tumor; Cell Differentiation; Cells, Cultured; Chromatin Immunoprecipitation; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Rearrangement; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Homeodomain Proteins; Humans; Immunophenotyping; Integrases; Leukemia, Myeloid, Acute; Lysine; Male; Methylation; Methyltransferases; Mice; Mice, Transgenic; Myeloid-Lymphoid Leukemia Protein; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Principal Component Analysis; Protein Methyltransferases; RNA, Small Interfering; Transcription, Genetic	2008
Transformation from committed progenitor to leukemia stem cells. Annals of the New York Academy of Sciences, 2009, Volume: 1176 Topics: Animals; Cell Transformation, Neoplastic; Hematopoietic Stem Cells; Histones; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells	2009
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia. Blood, 2010, Nov-04, Volume: 116, Issue:18 Topics: Adolescent; Antigens, CD34; Child; Child, Preschool; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Histones; Humans; Infant; Leukemia, Myeloid, Acute; Lysine; Male; Methylation; Prognosis; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Tumor Cells, Cultured	2010
Antileukemic action of (-)-epicatechin in the spleen of rats with acute myeloid leukemia. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:12 Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Catechin; Cell Line; Comet Assay; DNA Damage; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Leukemia, Myeloid, Acute; Methylation; Organ Size; Oxidation-Reduction; Phosphatidylserines; Purines; Rats; Spleen	2010
Epigenetic inactivation of the miR-124-1 in haematological malignancies. PloS one, 2011, Apr-22, Volume: 6, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase 6; Epigenesis, Genetic; Female; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methylation; MicroRNAs; Middle Aged; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; Young Adult	2011
Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:1 Topics: 5'-Nucleotidase; Antimetabolites, Antineoplastic; Base Sequence; Blotting, Western; Cell Line; Cell Line, Tumor; Child; Cytarabine; Cytosol; DNA; Electrophoretic Mobility Shift Assay; Exons; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Luciferases; Methylation; Molecular Sequence Data; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors	2011
New strategies in acute myeloid leukemia: redefining prognostic markers to guide therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Oct-01, Volume: 18, Issue:19 Topics: Apoptosis; Chromosome Aberrations; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Methylation; Mutation; Pathology, Molecular; Prognosis; Signal Transduction	2012
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer cell, 2012, Aug-14, Volume: 22, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Hematopoietic System; Histones; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Methylation; Mice; Mutation; Myeloid Cells; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Protein Binding; ras Proteins; Repressor Proteins; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Up-Regulation	2012
Predicting infections in high-risk patients with myelodysplastic syndrome/acute myeloid leukemia treated with azacitidine: a retrospective multicenter study. American journal of hematology, 2013, Volume: 88, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Disease Susceptibility; Female; Humans; Incidence; Infections; Israel; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Retrospective Studies; Risk Factors; Severity of Illness Index; Thrombocytopenia	2013
Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes. Blood, 2004, Jan-15, Volume: 103, Issue:2 Topics: Aged; Apoptosis; Apoptosis Regulatory Proteins; Bone Marrow Cells; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Death-Associated Protein Kinases; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Myelodysplastic Syndromes; Polymerase Chain Reaction	2004
Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications. Oncogene, 2006, Nov-09, Volume: 25, Issue:53 Topics: Cell Shape; Cytogenetics; Female; Gene Regulatory Networks; Humans; Leukemia, Myeloid, Acute; Male; Mass Spectrometry; Methylation; Protein Processing, Post-Translational; Proteome; Proteomics; Risk Factors	2006
Effect of 5-azacytidine on differentiation and DNA methylation in human promyelocytic leukemia cells (HL-60). Cancer research, 1983, Volume: 43, Issue:2 Topics: Azacitidine; Cell Differentiation; Cell Line; Clone Cells; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Methylation; Methyltransferases; Superoxides; Tetradecanoylphorbol Acetate	1983
5-aza-2'-deoxycytidine therapy in patients with acute leukemia inhibits DNA methylation. Leukemia research, 1984, Volume: 8, Issue:2 Topics: Azacitidine; Cell Line; Decitabine; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methylation	1984
Excretion of polyamines by children with leukemia during chemotherapy. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84 Topics: Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methylation; Neuroblastoma; Polyamines; Putrescine; RNA, Transfer; Spermidine; Vincristine	1983
The control of phospholipid methylation by phorbol diesters in differentiating human myeloid HL-60 leukemia cells. Carcinogenesis, 1982, Volume: 3, Issue:8 Topics: Alkaloids; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Methylation; Methyltransferases; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Tetradecanoylphorbol Acetate	1982
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester. Blood, 1981, Volume: 58, Issue:2 Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors	1981
Abnormal regional hypermethylation of the calcitonin gene in myelodysplastic syndromes. Leukemia research, 1995, Volume: 19, Issue:10 Topics: Aged; Base Sequence; Blotting, Southern; Calcitonin; Humans; Leukemia, Myeloid, Acute; Methylation; Middle Aged; Molecular Sequence Data; Myelodysplastic Syndromes; Polymerase Chain Reaction; Survival Rate	1995
Molecular analysis of CD2 gene expression in acute myeloblastic leukemia expressing T-lineage associated surface antigens. Leukemia & lymphoma, 1995, Volume: 16, Issue:3-4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Surface; Blotting, Northern; Blotting, Southern; CD2 Antigens; Gene Expression Regulation, Leukemic; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Methylation; RNA, Messenger; T-Lymphocytes	1995
Structural characterization of intermediates in the biosynthetic pathway of neolacto glycosphingolipids: differential expression in human leukaemia cells. Glycobiology, 1994, Volume: 4, Issue:3 Topics: Carbohydrate Sequence; Cell Differentiation; Galactosyltransferases; Glycosphingolipids; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Methylation; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured	1994
Hypomethylated status, but not RAG-1, is required for T-cell receptor-beta-chain gene rearrangement in acute leukemia cells. Cancer genetics and cytogenetics, 1994, Volume: 78, Issue:1 Topics: Acute Disease; Adult; Base Sequence; Burkitt Lymphoma; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, RAG-1; Humans; Leukemia, Myeloid, Acute; Methylation; Molecular Sequence Data	1994
A clonal study of hematopoiesis using the M27 beta probe: aberrant band patterns caused by incomplete digestion of a methyl-sensitive enzyme in the the inactive X-chromosome. Leukemia, 1993, Volume: 7, Issue:9 Topics: Blotting, Southern; DNA Probes; DNA Restriction Enzymes; Female; Hematopoiesis; Heterozygote; Humans; Leukemia, Myeloid, Acute; Methylation; Polymorphism, Restriction Fragment Length; Transcriptional Activation; X Chromosome	1993
Lineage specific demethylation of tal-1 gene breakpoint region determines the frequency of tal-1 deletions in alpha beta lineage T-cells. Oncogene, 1994, Volume: 9, Issue:7 Topics: Base Sequence; Basic Helix-Loop-Helix Transcription Factors; CD3 Complex; Cells, Cultured; Child; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Gene Deletion; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Methylation; Molecular Sequence Data; Oncogene Proteins, Fusion; Phenotype; Proteins; Proto-Oncogene Proteins; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; T-Cell Acute Lymphocytic Leukemia Protein 1; T-Lymphocytes; Transcription Factors; Tumor Cells, Cultured	1994
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer research, 1996, Feb-15, Volume: 56, Issue:4 Topics: Adult; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cell Line; Child; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 9; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Dinucleoside Phosphates; DNA; DNA, Neoplasm; Female; Genes, Tumor Suppressor; Glioma; Homozygote; Humans; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphocytes; Male; Methylation; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Reference Values; Restriction Mapping; Tumor Cells, Cultured; Tumor Suppressor Proteins	1996
Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance. Cancer, 2001, Jun-15, Volume: 91, Issue:12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p15; Genes, p16; Humans; Leukemia, Myeloid, Acute; Methylation; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Sensitivity and Specificity; Transcription Factors; Transcriptional Activation; Tumor Suppressor Proteins	2001
The aetiology of cancer in the very young. The British journal of cancer. Supplement, 1992, Volume: 18 Topics: Base Sequence; Carcinoma, Hepatocellular; Case-Control Studies; Child, Preschool; DNA; DNA Replication; Eye Neoplasms; Humans; Incidence; Infant; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Methylation; Models, Genetic; Registries; Retinoblastoma; United States; Wilms Tumor	1992
A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias. Blood, 1992, Oct-15, Volume: 80, Issue:8 Topics: Blotting, Northern; Blotting, Southern; DNA Probes; DNA, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methylation; Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1992
T-cell receptor beta chain gene rearrangement in acute myeloid leukemia always occurs at the allele that contains the undermethylated J beta 1 region. Cancer research, 1992, Dec-01, Volume: 52, Issue:23 Topics: Adolescent; Adult; Aged; Alleles; DNA, Neoplasm; Female; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Granulocytes; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Restriction Mapping	1992
Assessment of X-chromosome inactivation patterns using the hypervariable probe M27 beta in normal hemopoietic cells and acute myeloid leukemic blasts. Leukemia, 1992, Volume: 6, Issue:7 Topics: Bone Marrow Cells; DNA Probes; DNA, Neoplasm; Dosage Compensation, Genetic; Female; Hematopoietic Stem Cells; Heterozygote; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Myeloid, Acute; Methylation; Phosphoglycerate Kinase; Polymorphism, Restriction Fragment Length	1992
Genomic hypomethylation in human chronic lymphocytic leukemia. Blood, 1992, Oct-15, Volume: 80, Issue:8 Topics: Chromatography, High Pressure Liquid; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methylation; Multiple Myeloma; Ornithine Decarboxylase; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger	1992
Use of the polymerase chain reaction to detect hypermethylation in the calcitonin gene. A new, sensitive approach to monitor tumor cells in acute myelogenous leukemia. Leukemia research, 1992, Volume: 16, Issue:10 Topics: Base Sequence; Blotting, Southern; Bone Marrow; Calcitonin; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Methods; Methylation; Molecular Sequence Data; Monitoring, Physiologic; Polymerase Chain Reaction	1992
Presence of cell lineage-specific hypomethylated sites in the major breakpoint cluster region. Cancer research, 1990, Aug-15, Volume: 50, Issue:16 Topics: Blotting, Southern; DNA; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Methylation; Nucleic Acid Hybridization; Reference Values; Restriction Mapping	1990
Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2'-deoxycytidine. Leukemia research, 1985, Volume: 9, Issue:11 Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Line; Decitabine; Dimethyl Sulfoxide; DNA; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Methylation; Superoxides	1985
Inhibitory action of 10-deazaaminopterins and their polyglutamates on human thymidylate synthase. Molecular pharmacology, 1986, Volume: 30, Issue:2 Topics: Alkylation; Aminopterin; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Methylation; Peptides; Polyglutamic Acid; Structure-Activity Relationship; Thymidylate Synthase	1986
Determination of clonality in acute nonlymphocytic leukemia by restriction fragment length polymorphism and methylation analysis. Leukemia, 1987, Volume: 1, Issue:3 Topics: Acute Disease; Adult; Child, Preschool; Clone Cells; DNA, Neoplasm; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methylation; Middle Aged; Polymorphism, Restriction Fragment Length	1987
Induced rapid phospholipid methylation and arachidonic acid release by dimethyl sulfoxide-treated human promyelocytic leukemic HL-60 cells. Biochemical and biophysical research communications, 1986, Oct-30, Volume: 140, Issue:2 Topics: Arachidonic Acid; Arachidonic Acids; Cell Differentiation; Dimethyl Sulfoxide; Humans; Hydrolysis; Leukemia, Myeloid, Acute; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids	1986
Effect of neplanocin A on differentiation, nucleic acid methylation, and c-myc mRNA expression in human promyelocytic leukemia cells. Molecular pharmacology, 1985, Volume: 28, Issue:1 Topics: Adenosine; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cell Line; DNA, Neoplasm; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes; RNA, Neoplasm	1985
Chromatin structure of the c-myc gene in HL-60 cells during alterations of transcriptional activity. Cancer research, 1985, Volume: 45, Issue:10 Topics: Cell Line; Chromatin; Dimethyl Sulfoxide; DNA; Humans; Leukemia, Myeloid, Acute; Methylation; Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic	1985
Partial failure of methylation and cleavage of 45S RNA in the blast cells of acute leukaemia. Nature, 1970, Jun-20, Volume: 226, Issue:5251 Topics: Acute Disease; Centrifugation, Density Gradient; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methylation; RNA; Tritium; Uridine	1970
In vivo methylation of DNA in human leukocytes. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:1 Topics: Adenine; Cytosine; DNA; Guanine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methylation; Thymine; Tritium	1971