isomethyleugenol has been researched along with 2019 Novel Coronavirus Disease in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 32 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baranowski, MR; Benoni, R; Boura, E; Cahová, H; Kowalska, J; Krafcikova, P | 1 |
| Antoneli, F; Braconi, CT; Briones, MRS; Campos, JHC; Janini, LMR; Maricato, JT | 1 |
| Li, N; Rana, TM | 1 |
| Shirvaliloo, M | 1 |
| Cao, L; Chen, Y; Ebert, N; Gorbalenya, AE; Guo, D; Kindler, E; Liu, Q; Pan, R; Perlman, S; Sun, Y; Thiel, V; Zhang, Z; Zhou, Y; Züst, R | 1 |
| Chen, Q; Qing, X; Wang, K | 1 |
| Liu, H; Ma, J; Mao, Y; Zhang, L | 1 |
| Brescia, G; Buoli, M; Cannone, MG; Colapietro, P; Costantino, G; Croci, GA; Ferrara, M; Ferrero, S; Fontana, L; Gaudioso, G; Miozzo, MR; Montano, N; Piuma, C; Seia, M; Solbiati, M; Tabano, S; Tassi, L; Tobaldini, E | 1 |
| Bai, J; Chen, X; Gao, Y; Li, Z; Lu, J; Wang, P; Wang, W; Yong, H; Zheng, J | 1 |
| Shi, S; Tan, W; Zhou, H | 1 |
| Cao, Y; Chen, Y; Feng, J; Fu, Z; Guo, D; He, M; Jiang, A; Lan, K; Li, J; Liu, J; Tang, H; Wang, D; Wang, H; Wang, Y; Xu, K; Yan, K; Zeng, C; Zhang, L; Zhou, L; Zhou, X; Zhou, Y | 1 |
| Bignon, E; Dumont, E; Grandemange, S; Monari, A | 1 |
| Arefinia, N; Farokhnia, M; Ramezani, A; Sarvari, J; Yaghoubi, R; Zadeh, AMA | 1 |
| Li, H; Li, Y; Zhou, L | 1 |
| Encinar, JA; Menendez, JA | 1 |
| Han, Q; Hoffman, RM | 1 |
| Ahmed-Belkacem, R; Canard, B; Debart, F; Decroly, E; Guiraud, M; Sutto-Ortiz, P; Vasseur, JJ | 1 |
| Goyal, A; Kumar, S; Morla, S; Sharma, K | 1 |
| Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Cheng, Y; Daemen, LL; Kolesnikov, AI; Mamontov, E; Ramirez-Cuesta, AJ; Ryder, MR; Stone, MB | 1 |
| Faccin, L; Lapolla, A; Ragazzi, E; Sartore, G | 1 |
| Seliger, B; Subbarayan, K; Ulagappan, K; Wickenhauser, C | 1 |
| Bourgey, M; Bourque, G; Cheng, AP; Cheng, MP; Chiu, CY; De Vlaminck, I; Gu, W; Hsu, E; Marty, FM; Ritz, J; Schurr, E; Sesing Lenz, J; Vinh, DC | 1 |
| Cowling, VH; Fordyce, EAF; Gray, DW; Green, CJ; Pearson, LA; Petit, AP | 1 |
| Muthmann, N; Rentmeister, A; van Dülmen, M | 1 |
| Bolotokova, A; Devkota, K; Ghiabi, P; Hajian, T; Khalili Yazdi, A; Li, F; Perveen, S; Vedadi, M | 1 |
| Anderson, KG; Bray, B; Carlin, AF; Gonzalez, GM; Hui, H; Knight, R; Li, N; Rana, TM; Smith, D; Wang, Y; Zeller, M | 1 |
| Cai, T; Liang, C; Richard, S; Wang, Z; Yu, Z | 1 |
| Brunzelle, JS; Daczkowski, CM; Hoover, P; Inniss, NL; Mesecar, AD; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L | 1 |
| Bolotokova, A; Brown, PJ; Chau, I; Devkota, K; Fish, PV; Ghiabi, P; Hajian, T; Jin, J; Khalili Yazdi, A; Li, D; Li, F; Liu, J; Loppnau, P; Luo, M; Perveen, S; Satchell, KJF; Schapira, M; Smil, D; Vedadi, M; Wang, K | 1 |
| Chen, Z; Guan, W; Hao, H; Hu, X; Hu, Z; Liu, D; Ma, L; Yuan, J; Zhang, X; Zhang, Y | 1 |
3 review(s) available for isomethyleugenol and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
The unfavorable clinical outcome of COVID-19 in smokers is mediated by H3K4me3, H3K9me3 and H3K27me3 histone marks.
Topics: Angiotensin-Converting Enzyme 2; Cathepsin D; Cathepsin L; COVID-19; Dioxygenases; Epigenesis, Genetic; Histone Demethylases; Histones; Humans; Interleukin-6; Membrane Transport Proteins; Methylation; Neuropilin-1; Neuropilin-2; Nuclear Proteins; Protein Isoforms; Protein Processing, Post-Translational; Receptor, Angiotensin, Type 1; Receptors, Prostaglandin E; Risk Factors; SARS-CoV-2; Smoking; Virus Internalization | 2022 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
Oral Methioninase for Covid-19 Methionine-restriction Therapy.
Topics: Administration, Oral; Antiviral Agents; Bacterial Proteins; Betacoronavirus; Carbon-Sulfur Lyases; Clinical Trials as Topic; Coronavirus Infections; COVID-19; Cytokine Release Syndrome; Humans; Lymphocyte Activation; Macrophage Activation; Meta-Analysis as Topic; Methionine; Methylation; Pandemics; Pneumonia, Viral; Pseudomonas putida; Recombinant Proteins; RNA Caps; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; T-Lymphocyte Subsets; Virus Replication | 2020 |
1 trial(s) available for isomethyleugenol and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
29 other study(ies) available for isomethyleugenol and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase.
Topics: Chromatography, Liquid; COVID-19; Gene Expression Regulation, Viral; Humans; Mass Spectrometry; Methylation; Methyltransferases; RNA Caps; RNA, Viral; SARS-CoV-2; Substrate Specificity; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2021 |
Direct RNA Sequencing Reveals SARS-CoV-2 m6A Sites and Possible Differential DRACH Motif Methylation among Variants.
Topics: 3' Untranslated Regions; Adenosine; Animals; Chlorocebus aethiops; COVID-19; Genome, Viral; Humans; Immune Evasion; Methylation; Nanopore Sequencing; Open Reading Frames; RNA, Viral; SARS-CoV-2; Sequence Analysis, RNA; Vero Cells | 2021 |
Detection of N6-methyladenosine in SARS-CoV-2 RNA by methylated RNA immunoprecipitation sequencing.
Topics: Adenosine; Animals; Caco-2 Cells; Chlorocebus aethiops; COVID-19; Gene Expression; Gene Expression Regulation; Genetic Techniques; HEK293 Cells; Humans; Immunoprecipitation; Methylation; RNA; RNA Processing, Post-Transcriptional; RNA, Viral; SARS-CoV-2; Sequence Analysis, RNA; Vero Cells | 2022 |
N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
Topics: Animals; COVID-19; Guanine; Humans; Immunity, Innate; Interferon Type I; Methylation; Methyltransferases; Mice; Murine hepatitis virus; RNA Caps; RNA, Viral; SARS-CoV-2; Viral Nonstructural Proteins; Virulence; Virus Replication | 2022 |
m6A Regulator-Mediated Methylation Modification Patterns and Characteristics in COVID-19 Patients.
Topics: Adenosine; COVID-19; Humans; Methylation; Reproducibility of Results; RNA | 2022 |
LRTCLS: low-rank tensor completion with Laplacian smoothing regularization for unveiling the post-transcriptional machinery of N6-methylation (m6A)-mediated diseases.
Topics: Adenosine; Alternative Splicing; Carcinoma, Non-Small-Cell Lung; COVID-19; Humans; Lung Neoplasms; Methylation; MicroRNAs; RNA-Binding Proteins; RNA, Circular | 2022 |
Mental health and the effects on methylation of stress-related genes in front-line versus other health care professionals during the second wave of COVID-19 pandemic: an Italian pilot study.
Topics: Anxiety; COVID-19; Depression; Health Personnel; Histone Demethylases; Humans; Hypothalamo-Hypophyseal System; Mental Health; Methylation; Pandemics; Pilot Projects; Pituitary-Adrenal System; SARS-CoV-2; Serotonin Plasma Membrane Transport Proteins | 2023 |
GSK3326595 is a promising drug to prevent SARS-CoV-2 Omicron and other variants infection by inhibiting ACE2-R671 di-methylation.
Topics: Angiotensin-Converting Enzyme 2; Binding Sites; COVID-19; Humans; Methylation; Protein Binding; Protein-Arginine N-Methyltransferases; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2023 |
DeepGpgs: a novel deep learning framework for predicting arginine methylation sites combined with Gaussian prior and gated self-attention mechanism.
Topics: Arginine; COVID-19; Deep Learning; Humans; Methylation; Proteins; SARS-CoV-2 | 2023 |
NSUN2-mediated M
Topics: Animals; Antiviral Agents; COVID-19; Immunity, Innate; Interferon Regulatory Factor-3; Interferon Type I; Interferon-beta; Methylation; Mice; Mice, Knockout; SARS-CoV-2; Virus Diseases; Zika Virus; Zika Virus Infection | 2023 |
How SARS-CoV-2 Alters the Regulation of Gene Expression in Infected Cells.
Topics: COVID-19; Epigenesis, Genetic; Histones; Humans; Methylation; SARS-CoV-2 | 2023 |
Association of IFITM1 Promoter Methylation with Severity of SARS-CoV-2 Infection.
Topics: COVID-19; Cross-Sectional Studies; DNA Methylation; Female; Humans; Male; Methylation; Promoter Regions, Genetic; SARS-CoV-2 | 2023 |
EZH2-mediated H3K27me3 inhibits ACE2 expression.
Topics: Angiotensin-Converting Enzyme 2; Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Embryonic Stem Cells; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation; Gene Knockout Techniques; Histone Code; Histones; Humans; Lysine; Methylation; Mice; Organ Specificity; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Promoter Regions, Genetic; SARS-CoV-2; Transcription, Genetic; Up-Regulation | 2020 |
Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2'-O-Methylation of Viral RNA.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Immune Evasion; Immunity, Innate; Methylation; Models, Molecular; Pandemics; Pneumonia, Viral; RNA Processing, Post-Transcriptional; RNA, Viral; SARS-CoV-2 | 2020 |
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
Topics: Adenine; Betacoronavirus; Coronavirus Infections; COVID-19; Exoribonucleases; Humans; Methylation; Methyltransferases; Molecular Docking Simulation; Nucleosides; Pandemics; Pneumonia, Viral; RNA Caps; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins | 2020 |
Computational guided drug repurposing for targeting 2'-O-ribose methyltransferase of SARS-CoV-2.
Topics: Antiviral Agents; Betacoronavirus; Computational Biology; Coronavirus Infections; COVID-19; Drug Repositioning; Enzyme Inhibitors; Humans; Methylation; Methyltransferases; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; SARS-CoV-2; Sequence Homology, Amino Acid | 2020 |
High-resolution structures of the SARS-CoV-2 2'-
Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins | 2020 |
Hydration-Induced Disorder Lowers the Energy Barriers for Methyl Rotation in Drug Molecules.
Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; COVID-19; Crystallography, X-Ray; Dexamethasone; Hydroxychloroquine; Methylation; Models, Molecular; Water | 2020 |
A role of glycation and methylation for SARS-CoV-2 infection in diabetes?
Topics: Adipose Tissue; Angiotensin-Converting Enzyme 2; Biomarkers; Comorbidity; COVID-19; Diabetes Complications; Diabetes Mellitus, Type 2; DNA Methylation; Glycosylation; Humans; Immunoglobulin G; Insulin Resistance; Methylation; Multicenter Studies as Topic; Neoplasms; Protein Domains; Renin-Angiotensin System; Retrospective Studies; SARS-CoV-2; Up-Regulation | 2020 |
Expression and Clinical Significance of SARS-CoV-2 Human Targets in Neoplastic and Non-Neoplastic Lung Tissues.
Topics: Adenocarcinoma of Lung; Angiotensin-Converting Enzyme 2; COVID-19; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Methylation; Promoter Regions, Genetic; SARS-CoV-2; Serine Endopeptidases; Smoking; Up-Regulation | 2021 |
Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity.
Topics: Cell-Free Nucleic Acids; COVID-19; Humans; Methylation; SARS-CoV-2; Virus Diseases | 2021 |
Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
Topics: Antiparasitic Agents; Antiviral Agents; Cloning, Molecular; COVID-19; Drug Repositioning; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Exoribonucleases; Gene Expression; Genetic Vectors; High-Throughput Screening Assays; Humans; Kinetics; Mass Spectrometry; Methylation; Nitro Compounds; Prescription Drugs; Recombinant Fusion Proteins; RNA Caps; RNA, Viral; SARS-CoV-2; Small Molecule Libraries; Thiazoles; Viral Nonstructural Proteins; Virus Replication | 2021 |
Chemo-Enzymatic Modification of the 5' Cap Maintains Translation and Increases Immunogenic Properties of mRNA.
Topics: Chromatography, High Pressure Liquid; COVID-19; Genes, Reporter; HEK293 Cells; Humans; Mass Spectrometry; Methylation; Methyltransferases; Protein Biosynthesis; Protein Domains; RNA Caps; RNA, Messenger; S-Adenosylmethionine; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2021 |
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.
Topics: Adenosine; Cloning, Molecular; COVID-19; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genetic Vectors; High-Throughput Screening Assays; Humans; Kinetics; Methylation; Methyltransferases; Models, Molecular; Recombinant Proteins; RNA Caps; RNA, Viral; SARS-CoV-2; Tritium; Viral Nonstructural Proteins; Viral Regulatory and Accessory Proteins | 2021 |
METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection.
Topics: Adenosine; Cell Line; COVID-19; DEAD Box Protein 58; Humans; Immunity, Innate; Methylation; Methyltransferases; Receptors, Immunologic; RNA, Viral; SARS-CoV-2; Signal Transduction | 2021 |
Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication.
Topics: Amino Acid Motifs; Arginine; COVID-19; Cytoplasmic Granules; HEK293 Cells; Humans; Methylation; Nucleocapsid Proteins; RNA Stability; RNA, Viral; SARS-CoV-2; Virus Replication | 2021 |
Mn
Topics: Amino Acid Sequence; Catalytic Domain; COVID-19; Crystallography, X-Ray; Humans; Manganese; Methylation; Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Recombinant Proteins; RNA Caps; RNA Stability; RNA, Messenger; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Signal Transduction; Substrate Specificity; Viral Nonstructural Proteins | 2021 |
Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors.
Topics: Antiviral Agents; Binding Sites; COVID-19; Exoribonucleases; Humans; Methylation; Pandemics; Protein Binding; RNA, Viral; SARS-CoV-2; Viral Nonstructural Proteins; Virus Replication | 2021 |
Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; COVID-19; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Protein Processing, Post-Translational; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Virus Replication | 2021 |