isoleucine has been researched along with Obesity in 38 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (26.32) | 18.7374 |
1990's | 4 (10.53) | 18.2507 |
2000's | 6 (15.79) | 29.6817 |
2010's | 11 (28.95) | 24.3611 |
2020's | 7 (18.42) | 2.80 |
Authors | Studies |
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Caspers, MPM; Gart, E; Keijer, J; Kleemann, R; Menke, A; Morrison, MC; Salic, K; Snabel, J; van Duyvenvoorde, W; van Trigt, N | 1 |
Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
Lenart-Lipinska, M; Matyjaszek-Matuszek, B; Szmygin, H; Szydelko, J; Wozniak, S | 1 |
Bloks, VW; C L van den Munckhof, I; Chen, L; Doestzada, M; Fu, J; Joosten, LAB; Kuipers, F; Kurilshikov, A; Netea, MG; Riksen, NP; Rutten, JHW; van Faassen, M; Wang, D; Wijmenga, C; Zhernakova, A; Zhernakova, DV | 1 |
Feinle-Bisset, C; Heilbronn, L; Kritas, S; Li, H; Lim, SM; O'Rielly, R; Page, AJ; Ullrich, SS; Yazbeck, R | 1 |
Hu, X; Jin, H; Li, J; Shao, D; Shi, J; Yan, X | 1 |
Alexander, CM; Baur, JA; Brinkman, JA; Cheng, EP; Finke, M; Flores, V; Green, CL; Haider, LR; Jang, C; Kasza, I; Konon, EN; Lamming, DW; Malecki, KC; Miller, BR; Murphy, ME; Nikodemova, M; Pak, HH; Quinn, WJ; Rabinowitz, JD; Richardson, NE; Rojas, JM; Sonsalla, M; Spicer, AB; Tomasiewicz, JL; Wakai, MH; Yang, SE; Yu, D | 1 |
Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C | 1 |
Astrup, A; Bendtsen, LQ; Bertram, HC; Gomes, S; Holst, JJ; Liaset, B; Reitelseder, S; Ritz, C; Schmedes, M; Sjödin, A; Sundekilde, UK; Young, JF | 1 |
Aguilar-Salinas, CA; Bojalil, R; Canizales-Quinteros, S; Domínguez-López, A; Guillén-Pineda, LE; Gutiérrez-Vidal, R; Jacobo-Albavera, L; Larrieta-Carrasco, E; León-Mimila, P; López-Contreras, BE; Mejía-Domínguez, AM; Méndez-Sánchez, N; Romero-Hidalgo, S; Sánchez-Muñoz, F; Villamil-Ramírez, H; Villarreal-Molina, T | 1 |
Chen, G; Hajnal, A; Lynch, CJ; Olson, KC; Xu, Y | 1 |
Chen, J; Ding, G; Du, G; Fan, G; Feng, Y; Gao, S; He, D; Hu, Y; Li, H; Li, Y; Liu, T; Lu, L; Wang, Z; Wu, F; Xu, S; Xue, Z; Zhou, J; Zhu, X | 1 |
Avalos-Soriano, A; De la Cruz-Cordero, R; Garcia-Gasca, T; Rosado, JL | 1 |
Albala, C; Amador, P; Marti, A; Martínez, JA; Santos, JL; Valladares, M | 1 |
Djan, I; Djan, M; Plećas, A; Srdić, B; Stokić, E; Vapa, Lj | 1 |
Bassols, J; Botas, P; Delgado, E; Fernández-Real, JM; Menéndez, JA; Moreno-Navarrete, JM; Ortega, FJ; Pardo, G; Ricart, W; Valdés, S; Vázquez-Martín, A | 1 |
Cheng, M; Lindpaintner, K; Liu, L; Liu, X; Ma, L; Ma, X; Peng, Z; Ruan, X; Wang, B; Wang, S; Wang, X; Zhang, J | 1 |
Arakawa, M; Masaki, T; Nishimura, J; Seike, M; Yoshimatsu, H | 1 |
Hamamoto, R; Inamori, T; Sakakibara, H; Shimoi, K; Suzuki, A; Tatsumi, A; Tsuboi, H; Yamakawa-Kobayashi, K | 1 |
Clish, CB; Deik, AA; Fleischman, A; Gerszten, RE; Grinspoon, SK; McCarthy, MA; McCormack, SE; Mootha, VK; Shaham, O; Wang, TJ | 1 |
Breil, V; Broca, C; Cruciani-Guglielmacci, C; Derouet, M; Gross, R; Ktorza, A; Manteghetti, M; Pau, B; Petit, P; Reach, G; Ribes, G; Rizkalla, S; Rouault, C; Taouis, M | 1 |
Baier, LJ; Bogardus, C; Hanson, RL; Harper, I; Infante, AM; Kovacs, P; Tataranni, PA | 1 |
Altmann, S; Augstein, P; Berg, S; Demuth, HU; Freyse, EJ; Heinke, P; Salzsieder, E | 1 |
Abumrad, NN; Flakoll, PJ; Hill, JO; May, MM; Rice, DE | 1 |
Demuth, HU; McIntosh, CH; Pauly, RP; Pederson, RA; Schlenzig, D; White, HA | 1 |
Albu, J; Allison, DB; Burn, P; Chin, W; Deng, N; Duprat, L; Fisher, SL; Franco, LS; Gu, W; Heymsfield, S; Kissebah, A; Kleyn, PW; Lee, J; Maruti, S; Nathan, J; Pi-Sunyer, FX; Tu, Z; Yagaloff, KA | 1 |
Häring, H; Jacob, S; Machicao, F; Rettig, A; Stumvoll, M; Wahl, HG | 1 |
Chaussain, JL; Georges, P; Job, JC; Olive, G | 1 |
Cama, A; de la Luz Sierra, M; Gorden, P; Imperato-McGinley, J; Kadowaki, T; Ottini, L; Taylor, SI | 1 |
Herbertz, L; Langer, K; Schauder, P; Zavelberg, D | 1 |
Allen, CE; Campion, DR; Hausman, GJ; Martin, RJ; Shapira, JF | 1 |
Lernmark, A | 1 |
Owen, OE; Pozefsky, T; Sapir, DG; Walser, M | 1 |
Genuth, SM | 1 |
Adibi, SA; Drash, AL | 1 |
Adibi, SA | 1 |
Cahill, GF; Felig, P; Marliss, E | 1 |
Drenick, EJ; Figueroa, WS; Swendseid, ME; Villalobos, J | 1 |
2 review(s) available for isoleucine and Obesity
Article | Year |
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Branched-chain amino acids as a novel biomarker of metabolic disturbances in women with polycystic ovary syndrome - literature review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Obesity; Polycystic Ovary Syndrome; Prediabetic State; Valine | 2022 |
4-Hydroxyisoleucine from Fenugreek (Trigonella foenum-graecum): Effects on Insulin Resistance Associated with Obesity.
Topics: Animals; Glucose; Humans; In Vitro Techniques; Insulin Resistance; Isoleucine; Liver; Liver Function Tests; MAP Kinase Signaling System; Obesity; Plant Extracts; Trigonella | 2016 |
1 trial(s) available for isoleucine and Obesity
Article | Year |
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The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects.
Topics: Adult; Caseins; Female; Humans; Isoleucine; Male; Obesity; Overweight; Plasma; Postprandial Period; Tyrosine; Urine; Whey Proteins; Young Adult | 2018 |
35 other study(ies) available for isoleucine and Obesity
Article | Year |
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Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.
Topics: Amino Acids, Branched-Chain; Animals; Diglycerides; Hyperinsulinism; Inflammation; Isoleucine; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Valine | 2022 |
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan.
Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine | 2022 |
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.
Topics: Amino Acids, Branched-Chain; Atherosclerosis; Cross-Sectional Studies; Diabetes Mellitus; Humans; Isoleucine; Mendelian Randomization Analysis; Obesity; Valine | 2022 |
The Effect of Isoleucine Supplementation on Body Weight Gain and Blood Glucose Response in Lean and Obese Mice.
Topics: Animals; Blood Glucose; Diet, High-Fat; Dietary Supplements; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyperglycemia; Isoleucine; Male; Mice, Inbred C57BL; Negative Results; Nutritional Physiological Phenomena; Obesity; Thinness; Weight Gain | 2020 |
The anti-obesity effects exerted by different fractions of Artemisia sphaerocephala Krasch polysaccharide in diet-induced obese mice.
Topics: Animals; Anti-Obesity Agents; Artemisia; Diet, High-Fat; Gastrointestinal Microbiome; Isoleucine; Leucine; Liver; Male; Mice; Mice, Inbred C57BL; Nitrogen; Obesity; Plant Extracts; Polysaccharides; Valine | 2021 |
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Topics: Adipose Tissue, White; Amino Acids, Branched-Chain; Animals; Body Mass Index; Diet; Energy Metabolism; Fibroblast Growth Factors; Humans; Isoleucine; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Protein Serine-Threonine Kinases; Uncoupling Protein 1; Valine | 2021 |
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine | 2018 |
Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children.
Topics: Age of Onset; Alanine Transaminase; Amino Acid Substitution; Case-Control Studies; Child; Female; Genetic Association Studies; Humans; Ideal Body Weight; Isoleucine; Lipase; Liver Diseases; Male; Membrane Proteins; Methionine; Mexico; Obesity; Overweight; Polymorphism, Single Nucleotide | 2013 |
Alloisoleucine differentiates the branched-chain aminoacidemia of Zucker and dietary obese rats.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adipose Tissue; Amino Acid Metabolism, Inborn Errors; Animals; Chromatography, Liquid; Diet, High-Fat; Isoleucine; Male; Obesity; Rats; Rats, Zucker | 2014 |
The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat.
Topics: Adipose Tissue; Animals; Binding Sites; CRISPR-Cas Systems; Disease Models, Animal; Energy Metabolism; Female; Homeostasis; Isoleucine; Leptin; Male; Mice, Obese; Models, Molecular; Mutation; Obesity; Protein Binding; Rats; Receptors, Leptin; Signal Transduction; Whole Genome Sequencing | 2016 |
Obesity and eating behaviour in a three-generation Chilean family with carriers of the Thrl50Ile mutation in the melanocortin-4 receptor gene.
Topics: Adult; Aged; Body Composition; Body Mass Index; Child; Chile; Family Characteristics; Feeding Behavior; Female; Gene Frequency; Heterozygote; Humans; Isoleucine; Male; Middle Aged; Mutation, Missense; Obesity; Pedigree; Penetrance; Receptor, Melanocortin, Type 4; Threonine | 2008 |
Polymorphism Val103Ile of the melanocortin-4 receptor gene in the Serbian population.
Topics: Adult; Amino Acid Substitution; Female; Heterozygote; Homozygote; Humans; Isoleucine; Male; Obesity; Polymorphism, Single Nucleotide; Receptor, Melanocortin, Type 4; Serbia; Valine | 2010 |
Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men.
Topics: Adipose Tissue; Adiposity; Adult; Age Factors; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Down-Regulation; Fatty Acid Synthase, Type I; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Time Factors; Valine; Waist-Hip Ratio; Weight Gain | 2009 |
TAQIB and I405V polymorphisms of CETP are moderately associated with obesity risk in the Chinese adult population.
Topics: Adult; Amino Acid Substitution; Asian People; Case-Control Studies; Cholesterol Ester Transfer Proteins; Deoxyribonucleases, Type II Site-Specific; Female; Genetic Predisposition to Disease; Genetics, Population; Humans; Isoleucine; Male; Middle Aged; Obesity; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk; Valine | 2010 |
Isoleucine prevents the accumulation of tissue triglycerides and upregulates the expression of PPARalpha and uncoupling protein in diet-induced obese mice.
Topics: Animals; Diet; Dietary Supplements; Drinking; Eating; Energy Metabolism; Gene Expression Regulation; Ion Channels; Isoleucine; Male; Mice; Mice, Inbred Strains; Mitochondrial Proteins; Obesity; PPAR alpha; Triglycerides; Uncoupling Protein 2; Uncoupling Protein 3; Up-Regulation; Weight Gain | 2010 |
Val1483Ile polymorphism in the fatty acid synthase gene was associated with depressive symptoms under the influence of psychological stress.
Topics: Adult; Alleles; Cross-Sectional Studies; Depression; Depressive Disorder; Epidemiologic Studies; Fatty Acid Synthase, Type I; Fatty Acid Synthases; Female; Genotype; Humans; Isoleucine; Japan; Male; Middle Aged; Obesity; Polymorphism, Genetic; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological | 2011 |
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.
Topics: Adolescent; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Body Mass Index; Child; Child Nutrition Disorders; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Longitudinal Studies; Male; Massachusetts; Obesity; Predictive Value of Tests; Valine | 2013 |
Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat.
Topics: Animals; Diabetes Mellitus, Experimental; Diet; Enzyme Activation; Glucose; Glucose Clamp Technique; Hyperinsulinism; Insulin; Insulin Resistance; Isoleucine; Lipids; Liver; Male; Muscle, Skeletal; Niacinamide; Obesity; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Rats, Zucker; Signal Transduction; Sucrose | 2004 |
A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians.
Topics: Adipose Tissue; Adult; Alleles; Carbohydrate Metabolism; Fatty Acid Synthases; Gene Frequency; Genetic Variation; Humans; Indians, North American; Isoleucine; Mutation, Missense; Obesity; Oxidation-Reduction; Valine | 2004 |
Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance.
Topics: Animals; Blood Glucose; Body Weight; Dipeptidyl-Peptidase IV Inhibitors; Fatty Acids, Nonesterified; Glucose; Glucose Intolerance; Incretins; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Male; Models, Animal; Obesity; Rats; Rats, Zucker; Thiazoles; Time Factors; Tissue Culture Techniques; Triglycerides | 2008 |
The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects.
Topics: Adult; Amino Acids; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Isoleucine; Leucine; Male; Obesity; Phenylalanine; Reference Values | 1994 |
Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide.
Topics: Administration, Oral; Animals; Blood Glucose; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Female; Glucose; Glucose Intolerance; Insulin; Isoleucine; Male; Obesity; Rats; Rats, Zucker; Reference Values; Thiazoles | 1998 |
Identification and functional analysis of novel human melanocortin-4 receptor variants.
Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Body Mass Index; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Isoleucine; Male; Methionine; Mice; Middle Aged; Obesity; Pedigree; Polymorphism, Single-Stranded Conformational; Receptor, Melanocortin, Type 4; Receptors, Peptide; Recombinant Proteins; Threonine; Valine | 1999 |
Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal.
Topics: Adult; Alleles; Aspartic Acid; Blood Glucose; Exons; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glutamic Acid; Glycerol; Humans; Insulin; Insulin Resistance; Isoleucine; Kinetics; Lipolysis; Male; Mutation; Obesity; Polymorphism, Genetic; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA; Serine; Sterol Esterase; Triglycerides | 2001 |
Effect of 24 hour fast in obese children.
Topics: Adolescent; Alanine; Blood Glucose; Child; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Insulin; Isoleucine; Ketone Bodies; Leucine; Male; Obesity; Valine | 1976 |
A mutation in the tyrosine kinase domain of the insulin receptor associated with insulin resistance in an obese woman.
Topics: Adult; Exons; Female; Fibroblasts; Humans; Insulin Resistance; Isoleucine; Methionine; Mutation; Obesity; Protein-Tyrosine Kinases; Receptor, Insulin | 1991 |
Sex-specific differences in plasma branched-chain keto acid levels in obesity.
Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine | 1987 |
Metabolic characteristics of skeletal muscle from lean and obese Zucker rats.
Topics: Animals; Glucose; Histocytochemistry; Isoleucine; Male; Muscles; Obesity; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Rats; Rats, Zucker | 1987 |
Specificity of leucine stimulation of insulin release.
Topics: Amino Acids; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Iodine Isotopes; Islets of Langerhans; Isoleucine; Leucine; Mice; Obesity; Radioimmunoassay; Receptors, Cell Surface | 1972 |
Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects.
Topics: Amino Acids; Female; Humans; Infusions, Parenteral; Isoleucine; Keto Acids; Leucine; Methionine; Nitrogen; Obesity; Phenylalanine; Starvation; Urea; Valine | 1974 |
Effects of oral alanine administration in fasting obese subjects.
Topics: Administration, Oral; Adult; Alanine; Blood Glucose; Female; Gluconeogenesis; Humans; Hydroxybutyrates; Insulin; Isoleucine; Leucine; Male; Middle Aged; Nitrogen; Obesity; Phosphorus; Potassium; Urea; Uric Acid; Valine | 1973 |
Hormone and amino acid levels in altered nutritional states.
Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Female; Growth Hormone; Humans; Insulin; Isoleucine; Leucine; Male; Nutritional Physiological Phenomena; Obesity; Protein Deficiency; Starvation; Valine | 1970 |
Alteration in the urinary excretion rate of amino acids and nitrogen by dietary means in obese and normal human subjects.
Topics: Adult; Alanine; Amino Acids; Creatinine; Female; Humans; Isoleucine; Leucine; Male; Nitrogen; Obesity; Protein Deficiency; Renal Aminoacidurias; Starvation; Taurine; Urea; Valine | 1971 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |
The effects of test doses of leucine, isoleucine or valine on plasma amino acid levels. The unique effect of leucine.
Topics: Amino Acids; Blood; Fasting; Humans; Isoleucine; Leucine; Male; Obesity; Valine | 1965 |