isoleucine has been researched along with Intellectual Disability in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (73.91) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denman, RB; He, XY; Malik, M; McMenamin, J; Olpin, SE; Philipp, M; Sutton, VR; Yang, SY | 1 |
| Andresen, BS; Berry, SA; He, M; Lussky, RC; Madsen, PP; Matern, D; Rinaldo, P; van Calcar, SC; Vockley, J; Whitley, CB; Wolff, JA | 1 |
| MACKENZIE, DY; WOOLF, LI | 1 |
| Ben-Omran, TI; Blaser, S; Callahan, J; Feigenbaum, A; Phillips, H | 1 |
| Efron, ML | 1 |
| Arakawa, T; Dancis, J; Hutzler, J; Morikawa, T; Tada, K; Wada, Y | 1 |
| Bennett, MJ; Bertini, E; Burlina, AB; Dionisi-Vici, C; Gibson, KM; Hale, DE; Sabetta, G; Schmidt-Sommerfeld, E; Servidei, S; Zacchello, F | 1 |
| Brand, J; Hoffmann, GF; Lindner, M; Mayatepek, E; Ruiter, JP; Wanders, RJ; Zschocke, J | 1 |
| Fischer, U; Keidel, EM; Laggerbauer, B; Ostareck, D; Ostareck-Lederer, A | 1 |
| Bachmann, C; Baumgartner, R; Bremer, HJ; Bruinvis, L; Duran, M; Irle, U; Ketting, D; Przyrembel, H; Wadman, SK | 1 |
| Grüttner, R; Held, KR; Plettner, C; Singh, S; Sternowsky, HJ | 1 |
| Baños, G; Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Ionasescu, V; Mueller, S; Stegink, L; Weinstein, M | 1 |
| Oldendorf, WH | 1 |
| Iivanainen, M; Palo, J; Savolainen, H | 1 |
| Hansson, O; Tuvemo, T; Westphal, O | 1 |
| Hart, ZH; Krieger, I | 1 |
| Arjundas, G; Chamukuttan, S; Gajanan, N; Kalyanaraman, K; Ramamurthi, B | 1 |
| van der Horst, JL; Wadman, SK | 1 |
| Barness, LA; Morrow, G | 1 |
| Kolendrianos, ET; Schwartz, JF | 1 |
| Dickinson, JP; Holton, JB; Lewis, GM; Littlewood, JM; Steel, AE | 1 |
| Heeley, AF; McCubbing, DG; Shepherd, J | 1 |
1 review(s) available for isoleucine and Intellectual Disability
| Article | Year |
|---|---|
Prospective diagnosis of 2-methylbutyryl-CoA dehydrogenase deficiency in the Hmong population by newborn screening using tandem mass spectrometry.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Diagnosis, Differential; Diet, Protein-Restricted; DNA Mutational Analysis; Ethnicity; Exons; Female; Genetic Testing; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Male; Mass Spectrometry; Neonatal Screening; Oxidoreductases Acting on CH-CH Group Donors; Sequence Deletion; Treatment Outcome | 2003 |
22 other study(ies) available for isoleucine and Intellectual Disability
| Article | Year |
|---|---|
Mental retardation linked to mutations in the HSD17B10 gene interfering with neurosteroid and isoleucine metabolism.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Amino Acid Sequence; Animals; Base Sequence; Biocatalysis; Cells, Cultured; Fibroblasts; Humans; Intellectual Disability; Isoleucine; Male; Models, Molecular; Point Mutation; Protein Structure, Tertiary; Steroids | 2009 |
Maple syrup urine disease; an inborn error of the metabolism of valine, leucine, and isoleucine associated with gross mental deficiency.
Topics: Biochemical Phenomena; Child; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Valine | 1959 |
Atypical phenotype in a boy with a maple syrup urine disease.
Topics: Amino Acids, Branched-Chain; Brain; Cerebellum; Developmental Disabilities; Humans; Infant; Intellectual Disability; Isoleucine; Male; Maple Syrup Urine Disease; Phenotype | 2006 |
Isovaleric acidemia.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Chromatography, Gas; Fatty Acids; Female; Humans; Infant; Intellectual Disability; Isoleucine; Leucine; Male; Valine | 1967 |
Hypervalinemia. A defect in valine transamination.
Topics: Amino Acid Metabolism, Inborn Errors; Asian People; Carbon Isotopes; Child, Preschool; Female; Fetal Diseases; Humans; Intellectual Disability; Isoleucine; Japan; Keto Acids; Leucine; Leukocytes; Methionine; Phenylalanine; Placenta; Pregnancy; Transaminases; Valine | 1967 |
A new syndrome with ethylmalonic aciduria and normal fatty acid oxidation in fibroblasts.
Topics: Acyl-CoA Dehydrogenase; Brain; Chronic Disease; Cyanosis; Diarrhea; Fatty Acid Desaturases; Fatty Acids; Fibroblasts; Humans; Infant; Intellectual Disability; Isoleucine; Male; Malonates; Oxidation-Reduction; Paralysis; Purpura; Syndrome | 1994 |
Progressive infantile neurodegeneration caused by 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: a novel inborn error of branched-chain fatty acid and isoleucine metabolism.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Disease Progression; Fatty Acids; Hemophilia A; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Lipid Metabolism, Inborn Errors; Male; Mitochondria; Neurodegenerative Diseases; Oxidation-Reduction; Psychomotor Agitation; Seizures | 2000 |
Evidence that fragile X mental retardation protein is a negative regulator of translation.
Topics: Animals; Asparagine; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Intellectual Disability; Isoleucine; Microinjections; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oocytes; Peptide Chain Initiation, Translational; Protein Biosynthesis; Rabbits; Repressor Proteins; Ribosomal Proteins; RNA-Binding Proteins; RNA, Messenger; Xenopus laevis; Xenopus Proteins | 2001 |
Propionyl-CoA carboxylase deficiency with overflow of metabolites of isoleucine catabolism at all levels.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carboxy-Lyases; Child; Female; Fibroblasts; Humans; Intellectual Disability; Isoleucine; Muscle Spasticity; Paraplegia | 1979 |
[Intermittent branched--chain ketoacidurie in ketotic hypoglycemia: investigations to localize the biochemical defect (author's transl)].
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Child; Female; Fibroblasts; Humans; Hypoglycemia; Intellectual Disability; Isoleucine; Keto Acids; Ketosis; Leucine; Leukocytes; Valine | 1976 |
Inhibition of entry of some amino acids into the brain, with observations on mental retardation in the aminoacidurias.
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Arginine; Biological Transport, Active; Brain; Caproates; Carbon Radioisotopes; Depression, Chemical; Drug Interactions; Humans; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Threonine | 1974 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; Glutamine; Glycine; Histidine; Humans; Ichthyosis; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Muscle Spasticity; Retinal Degeneration; Serine; Syndrome; Valine | 1973 |
Saturation of blood brain barrier transport of amino acids in phenylketonuria.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Humans; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Free amino acids and carbohydrates in the cerebrospinal fluid of 305 mentally retarded patients: a screening study.
Topics: Adolescent; Adult; Alanine; Amino Acids; Arginine; Carbohydrates; Child; Child, Preschool; Chromatography, Thin Layer; Cystine; Epilepsy; Female; Glutamates; Glutamine; Humans; Intellectual Disability; Intelligence Tests; Isoleucine; Leucine; Lysine; Male; Metabolism, Inborn Errors; Methionine; Middle Aged; Ornithine; Phenylalanine; Pneumoencephalography; Threonine; Valine | 1973 |
[Diazoxide as therapy for idiopathic hypoglycemia in children (author's transl)].
Topics: Catecholamines; Child; Child, Preschool; Cyanosis; Diazoxide; Diet Therapy; Fasting; Female; Fever; Humans; Hypoglycemia; Infant; Infant, Newborn; Insulin; Intellectual Disability; Isoleucine; Leucine; Male; Microcephaly; Pregnancy; Seizures; Valine | 1974 |
Valine-sensitive nonketotic hyperglycinemia. Case report.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Benzoates; Brain Diseases; Brain Stem; Carbon Dioxide; Carbon Radioisotopes; Chromatography; Coma; Diet Therapy; Drug Hypersensitivity; Electroencephalography; Female; Glycine; Humans; Hydroxyproline; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Isoleucine; Valine | 1974 |
Maple syrup urine disease (branched-chain keto-aciduria) variant type manifesting as hyperkinetic behaviour and mental retardation. Report of two cases.
Topics: Child, Preschool; Humans; Hyperkinesis; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Pedigree; Pyruvates; Valine | 1972 |
A variant form of branched-chain keto aciduria.
Topics: Amino Acids; Child Behavior Disorders; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diet Therapy; Dietary Proteins; Female; Heterozygote; Humans; Infant; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Methionine; Motor Skills; Pedigree; Phenylketonurias; Tyrosine; Valine | 1971 |
Studies in a patient with methylmalonic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Diet; Dietary Proteins; Glycine; Humans; Infant; Infant, Newborn; Intellectual Disability; Isoleucine; Isomerases; Leucine; Male; Malonates; Valine; Vitamin B 12 | 1969 |
M aple syrup urine disease. A review with a report of an additional case.
Topics: Diet Therapy; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Valine | 1969 |
Maple syrup urine disease. Four years' experience with dietary treatment of a case.
Topics: Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Isoleucine; Leucine; Maple Syrup Urine Disease; Prognosis; Time Factors; Valine | 1969 |
Effect of pyridoxine on the metabolism of tryptophan and branched-chain amino acids in two mentally retarded sibs.
Topics: Child, Preschool; Female; Humans; Intellectual Disability; Isoleucine; Leucine; Male; Pyridines; Pyridoxine; Tryptophan; Valine | 1966 |