isoleucine and Disease Exacerbation

isoleucine has been researched along with Disease Exacerbation in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's5 (22.73)29.6817
2010's11 (50.00)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Bai, M; Chen, J; Dai, H; Han, F; Lin, W; Wang, J; Weng, C; Xie, X; Zhu, H1
Dong, ZY; Jin, WJ; Liu, M; Peng, L; Xu, MY; You, H; Zhou, C1
Chamberlain, JS; Ferretti, R; Lorena, MDSV; Matsumura, CY; Nagana Gowda, GA; Odom, GL; Santos, EKD1
Chang, S; Chu, X; Ding, J; Du, C; Feng, T; Ge, C; Geng, M; Gong, Y; Huang, X; Lian, W; Lin, F; Liu, J; Ruan, L; Sun, G; Wang, H; Wang, T; Wang, X; Xiao, S; Xie, Z; Yan, S; Yang, D; Yang, J; Zhang, G; Zhang, H; Zhang, J; Zhang, Q1
Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C1
Amagai, T; Haji, S; Kitagawa, M1
Akagi, A; Iwasaki, Y; Kitamoto, T; Mimuro, M; Yamada, M; Yoshida, M1
Belichenko, NP; Chin, FT; Condon, C; James, ML; Kuan, J; Longo, FM; Miao, Z; Semaan, S; Shuhendler, AJ; Simmons, DA1
Anthony, DC; Claridge, TDW; Jagielowicz, M; Probert, F; Simmons, A; Travis, S; Walsh, A; Yeo, T1
Cao, JL; Li, DQ; Shao, ZM; Sun, R; Xie, HY; Yang, LF; Zhang, FL1
Bregy, L; Bruderer, T; Eiffert, L; Engler, A; Gaugg, MT; Kohler, M; Nussbaumer-Ochsner, Y; Sinues, P; Zenobi, R1
Banerjee, G; Belichenko, NP; Finkle, C; Knowles, JK; Longo, FM; Massa, SM; Simmons, DA1
Antonov, AA; Chen, L; Guo, H; Hua, Y; Huang, Y; Li, R; Li, W; Liu, P; Tian, Y; Wang, L; Xu, F; Zhang, Z; Zhu, Y1
Doi, H; Kameda, T; Koyano, S; Kuroiwa, Y; Matsumoto, N; Miyaji, Y; Miyatake, S; Sawaishi, Y; Suzuki, Y; Tomita, A1
Hemmer, B; Kolb-Mäurer, A; Kroner, A; Kruse, N; Mäurer, M; Rieckmann, P; Toyka, KV; Vogel, F1
Datz, C; Ferenci, P; Hellerbrand, C; Kraus, MR; Norgauer, W; Osterreicher, CH; Schuppan, D; Stickel, F; Wölfel, M; Wrba, F1
Cho, H; Choi, BY; Hahn, DS; Ihm, C; Ju, H; Kang, C; Kim, JB; Kim, WH; Kim, YS; Noh, SM1
Antinori, A; Bertoli, A; Ceccherini-Silberstein, F; Forbici, F; Liuzzi, G; Lorenzini, P; Marconi, P; Mosti, S; Narciso, P; Perno, CF; Tozzi, V; Trotta, MP; Zaccarelli, M1
Chinnery, PF; Durward, WF; Johnson, MA; Taylor, RW; Turnbull, DM1
Brouwer, M; Coutinho, RA; de Roda Husman, AM; Goudsmit, J; Schuitemaker, H; van Rij, RP1
de Ana, AM; Martínez-A, C; Mellado, M; Rodríguez-Frade, JM; Vila-Coro, AJ1
Brand, J; Hoffmann, GF; Lindner, M; Mayatepek, E; Ruiter, JP; Wanders, RJ; Zschocke, J1

Other Studies

22 other study(ies) available for isoleucine and Disease Exacerbation

ArticleYear
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
    Nutrients, 2022, Aug-15, Volume: 14, Issue:16

    Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine

2022
A Novel Metabolic Score for Predicting the Acute Exacerbation in Patients with Chronic Obstructive Pulmonary Disease.
    International journal of chronic obstructive pulmonary disease, 2023, Volume: 18

    Topics: Disease Progression; Glutamine; Humans; Isoleucine; Pulmonary Disease, Chronic Obstructive; Pyruvates

2023
Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle.
    Skeletal muscle, 2023, 09-13, Volume: 13, Issue:1

    Topics: Acetic Acid; Alanine; Animals; Creatine; Disease Progression; Glycerol; Isoleucine; Methionine; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Duchenne; Phosphocreatine; Racemethionine; Tumor Necrosis Factor-alpha

2023
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.
    Cell research, 2019, Volume: 29, Issue:10

    Topics: Alzheimer Disease; Amino Acids; Animals; Anti-Bacterial Agents; Bacteria; Clinical Trials, Phase III as Topic; Cognitive Dysfunction; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Humans; Isoleucine; Mannose; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Oligosaccharides; Phenylalanine; Th1 Cells

2019
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:1

    Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine

2018
High Serum Essential Amino Acids as a Predictor of Skeletal Muscle Depletion in Patients With Cachexia and Advanced Gastrointestinal Cancers.
    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2017, Volume: 32, Issue:5

    Topics: Aged; Amino Acids, Essential; Antineoplastic Agents; Biomarkers; C-Reactive Protein; Cachexia; Disease Progression; Female; Gastrointestinal Neoplasms; Humans; Isoleucine; Japan; Leucine; Male; Medical Records; Neoplasm Staging; Psoas Muscles; Retrospective Studies; Risk; Sarcopenia; Tomography, X-Ray Computed; Up-Regulation

2017
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
    Prion, 2018, 01-02, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine

2018
TSPO-PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington's disease: preclinical evidence with the p75NTR ligand LM11A-31.
    Human molecular genetics, 2018, 08-15, Volume: 27, Issue:16

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Progression; Fluorodeoxyglucose F18; Hippocampus; Humans; Huntington Disease; Isoleucine; Male; Mice; Microglia; Morpholines; Positron-Emission Tomography; Protein Binding; Receptors, GABA; Receptors, Nerve Growth Factor

2018
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
    Journal of Crohn's & colitis, 2018, Nov-15, Volume: 12, Issue:11

    Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult

2018
Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer.
    Cancer research, 2018, 10-15, Volume: 78, Issue:20

    Topics: Alternative Splicing; Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Exons; Female; Heterogeneous-Nuclear Ribonucleoprotein Group M; Humans; Hyaluronan Receptors; Isoleucine; Methionine; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Isoforms; Transcription Factors; Triple Negative Breast Neoplasms

2018
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.
    Respirology (Carlton, Vic.), 2019, Volume: 24, Issue:5

    Topics: Aged; Alanine; Amino Acids; Area Under Curve; Biomarkers; Breath Tests; Case-Control Studies; Disease Progression; Exhalation; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Isoleucine; Leucine; Male; Middle Aged; ROC Curve; Spectrometry, Mass, Electrospray Ionization; Valine

2019
A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cholinergic Neurons; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Female; Humans; Isoleucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Nerve Degeneration; Neurites; Protective Agents; Receptor, Nerve Growth Factor; Signal Transduction

2014
Discovery of Metabolite Biomarkers for Acute Ischemic Stroke Progression.
    Journal of proteome research, 2017, 02-03, Volume: 16, Issue:2

    Topics: Aged; Betaine; Biomarkers; Disease Progression; Early Diagnosis; Female; Humans; Isoleucine; Male; Metabolome; Metabolomics; Middle Aged; ROC Curve; Serine; Stroke

2017
Siblings with the adult-onset slowly progressive type of pantothenate kinase-associated neurodegeneration and a novel mutation, Ile346Ser, in PANK2: clinical features and (99m)Tc-ECD brain perfusion SPECT findings.
    Journal of the neurological sciences, 2010, Mar-15, Volume: 290, Issue:1-2

    Topics: Age of Onset; Amino Acid Substitution; Brain; Cerebrovascular Circulation; Disease Progression; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycopeptides; Humans; Isoleucine; Male; Middle Aged; Mutation; Organotechnetium Compounds; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Serine; Siblings; Tomography, Emission-Computed, Single-Photon

2010
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis.
    Journal of neuroimmunology, 2005, Volume: 165, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Cells, Cultured; Cytokines; Disease Progression; Germany; Glycine; Humans; Isoleucine; Membrane Glycoproteins; Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; Receptors, Cell Surface; T-Lymphocytes, Regulatory; Threonine; Toll-Like Receptor 4; Toll-Like Receptors

2005
Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis.
    Archives of internal medicine, 2005, Sep-12, Volume: 165, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Disease Progression; Female; Genotype; Glutathione Transferase; Hemochromatosis; Hepatitis C, Chronic; Humans; Isoleucine; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Prognosis; Valine

2005
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.
    Cancer letters, 2006, Oct-28, Volume: 242, Issue:2

    Topics: Alleles; Aurora Kinase A; Aurora Kinases; Case-Control Studies; Disease Progression; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Isoleucine; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Risk; Stomach Neoplasms; Valine

2006
The V118I mutation as a marker of advanced HIV infection and disease progression.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Disease Progression; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Logistic Models; Male; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Risk Assessment; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Failure; Valine

2007
A novel mitochondrial tRNA isoleucine gene mutation causing chronic progressive external ophthalmoplegia.
    Neurology, 1997, Volume: 49, Issue:4

    Topics: Adult; Chronic Disease; Cytochrome-c Oxidase Deficiency; Disease Progression; Electron Transport Complex IV; Female; Humans; Isoleucine; Muscle Fibers, Skeletal; Muscle, Skeletal; Ophthalmoplegia; Point Mutation; RNA; RNA, Mitochondrial; RNA, Transfer

1997
Role of CCR2 genotype in the clinical course of syncytium-inducing (SI) or non-SI human immunodeficiency virus type 1 infection and in the time to conversion to SI virus variants.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:6

    Topics: Cells, Cultured; Confidence Intervals; Disease Progression; Genetic Variation; Genotype; Giant Cells; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Isoleucine; Leukocytes, Mononuclear; Male; Point Mutation; Proportional Hazards Models; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Time Factors; Valine

1998
Chemokine control of HIV-1 infection.
    Nature, 1999, Aug-19, Volume: 400, Issue:6746

    Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemokine CCL2; Chemokine CXCL12; Chemokines, CXC; Dimerization; Disease Progression; HIV Infections; HIV-1; Humans; Isoleucine; Point Mutation; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Cytokine; Valine

1999
Progressive infantile neurodegeneration caused by 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: a novel inborn error of branched-chain fatty acid and isoleucine metabolism.
    Pediatric research, 2000, Volume: 48, Issue:6

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Disease Progression; Fatty Acids; Hemophilia A; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Lipid Metabolism, Inborn Errors; Male; Mitochondria; Neurodegenerative Diseases; Oxidation-Reduction; Psychomotor Agitation; Seizures

2000