isoleucine has been researched along with Disease Exacerbation in 22 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (13.64) | 18.2507 |
2000's | 5 (22.73) | 29.6817 |
2010's | 11 (50.00) | 24.3611 |
2020's | 3 (13.64) | 2.80 |
Authors | Studies |
---|---|
Bai, M; Chen, J; Dai, H; Han, F; Lin, W; Wang, J; Weng, C; Xie, X; Zhu, H | 1 |
Dong, ZY; Jin, WJ; Liu, M; Peng, L; Xu, MY; You, H; Zhou, C | 1 |
Chamberlain, JS; Ferretti, R; Lorena, MDSV; Matsumura, CY; Nagana Gowda, GA; Odom, GL; Santos, EKD | 1 |
Chang, S; Chu, X; Ding, J; Du, C; Feng, T; Ge, C; Geng, M; Gong, Y; Huang, X; Lian, W; Lin, F; Liu, J; Ruan, L; Sun, G; Wang, H; Wang, T; Wang, X; Xiao, S; Xie, Z; Yan, S; Yang, D; Yang, J; Zhang, G; Zhang, H; Zhang, J; Zhang, Q | 1 |
Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C | 1 |
Amagai, T; Haji, S; Kitagawa, M | 1 |
Akagi, A; Iwasaki, Y; Kitamoto, T; Mimuro, M; Yamada, M; Yoshida, M | 1 |
Belichenko, NP; Chin, FT; Condon, C; James, ML; Kuan, J; Longo, FM; Miao, Z; Semaan, S; Shuhendler, AJ; Simmons, DA | 1 |
Anthony, DC; Claridge, TDW; Jagielowicz, M; Probert, F; Simmons, A; Travis, S; Walsh, A; Yeo, T | 1 |
Cao, JL; Li, DQ; Shao, ZM; Sun, R; Xie, HY; Yang, LF; Zhang, FL | 1 |
Bregy, L; Bruderer, T; Eiffert, L; Engler, A; Gaugg, MT; Kohler, M; Nussbaumer-Ochsner, Y; Sinues, P; Zenobi, R | 1 |
Banerjee, G; Belichenko, NP; Finkle, C; Knowles, JK; Longo, FM; Massa, SM; Simmons, DA | 1 |
Antonov, AA; Chen, L; Guo, H; Hua, Y; Huang, Y; Li, R; Li, W; Liu, P; Tian, Y; Wang, L; Xu, F; Zhang, Z; Zhu, Y | 1 |
Doi, H; Kameda, T; Koyano, S; Kuroiwa, Y; Matsumoto, N; Miyaji, Y; Miyatake, S; Sawaishi, Y; Suzuki, Y; Tomita, A | 1 |
Hemmer, B; Kolb-Mäurer, A; Kroner, A; Kruse, N; Mäurer, M; Rieckmann, P; Toyka, KV; Vogel, F | 1 |
Datz, C; Ferenci, P; Hellerbrand, C; Kraus, MR; Norgauer, W; Osterreicher, CH; Schuppan, D; Stickel, F; Wölfel, M; Wrba, F | 1 |
Cho, H; Choi, BY; Hahn, DS; Ihm, C; Ju, H; Kang, C; Kim, JB; Kim, WH; Kim, YS; Noh, SM | 1 |
Antinori, A; Bertoli, A; Ceccherini-Silberstein, F; Forbici, F; Liuzzi, G; Lorenzini, P; Marconi, P; Mosti, S; Narciso, P; Perno, CF; Tozzi, V; Trotta, MP; Zaccarelli, M | 1 |
Chinnery, PF; Durward, WF; Johnson, MA; Taylor, RW; Turnbull, DM | 1 |
Brouwer, M; Coutinho, RA; de Roda Husman, AM; Goudsmit, J; Schuitemaker, H; van Rij, RP | 1 |
de Ana, AM; Martínez-A, C; Mellado, M; Rodríguez-Frade, JM; Vila-Coro, AJ | 1 |
Brand, J; Hoffmann, GF; Lindner, M; Mayatepek, E; Ruiter, JP; Wanders, RJ; Zschocke, J | 1 |
22 other study(ies) available for isoleucine and Disease Exacerbation
Article | Year |
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Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine | 2022 |
A Novel Metabolic Score for Predicting the Acute Exacerbation in Patients with Chronic Obstructive Pulmonary Disease.
Topics: Disease Progression; Glutamine; Humans; Isoleucine; Pulmonary Disease, Chronic Obstructive; Pyruvates | 2023 |
Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle.
Topics: Acetic Acid; Alanine; Animals; Creatine; Disease Progression; Glycerol; Isoleucine; Methionine; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Duchenne; Phosphocreatine; Racemethionine; Tumor Necrosis Factor-alpha | 2023 |
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.
Topics: Alzheimer Disease; Amino Acids; Animals; Anti-Bacterial Agents; Bacteria; Clinical Trials, Phase III as Topic; Cognitive Dysfunction; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Humans; Isoleucine; Mannose; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Oligosaccharides; Phenylalanine; Th1 Cells | 2019 |
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine | 2018 |
High Serum Essential Amino Acids as a Predictor of Skeletal Muscle Depletion in Patients With Cachexia and Advanced Gastrointestinal Cancers.
Topics: Aged; Amino Acids, Essential; Antineoplastic Agents; Biomarkers; C-Reactive Protein; Cachexia; Disease Progression; Female; Gastrointestinal Neoplasms; Humans; Isoleucine; Japan; Leucine; Male; Medical Records; Neoplasm Staging; Psoas Muscles; Retrospective Studies; Risk; Sarcopenia; Tomography, X-Ray Computed; Up-Regulation | 2017 |
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine | 2018 |
TSPO-PET imaging using [18F]PBR06 is a potential translatable biomarker for treatment response in Huntington's disease: preclinical evidence with the p75NTR ligand LM11A-31.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Progression; Fluorodeoxyglucose F18; Hippocampus; Humans; Huntington Disease; Isoleucine; Male; Mice; Microglia; Morpholines; Positron-Emission Tomography; Protein Binding; Receptors, GABA; Receptors, Nerve Growth Factor | 2018 |
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult | 2018 |
Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer.
Topics: Alternative Splicing; Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Progression; Epithelial-Mesenchymal Transition; Exons; Female; Heterogeneous-Nuclear Ribonucleoprotein Group M; Humans; Hyaluronan Receptors; Isoleucine; Methionine; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Isoforms; Transcription Factors; Triple Negative Breast Neoplasms | 2018 |
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.
Topics: Aged; Alanine; Amino Acids; Area Under Curve; Biomarkers; Breath Tests; Case-Control Studies; Disease Progression; Exhalation; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Isoleucine; Leucine; Male; Middle Aged; ROC Curve; Spectrometry, Mass, Electrospray Ionization; Valine | 2019 |
A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cholinergic Neurons; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Female; Humans; Isoleucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Nerve Degeneration; Neurites; Protective Agents; Receptor, Nerve Growth Factor; Signal Transduction | 2014 |
Discovery of Metabolite Biomarkers for Acute Ischemic Stroke Progression.
Topics: Aged; Betaine; Biomarkers; Disease Progression; Early Diagnosis; Female; Humans; Isoleucine; Male; Metabolome; Metabolomics; Middle Aged; ROC Curve; Serine; Stroke | 2017 |
Siblings with the adult-onset slowly progressive type of pantothenate kinase-associated neurodegeneration and a novel mutation, Ile346Ser, in PANK2: clinical features and (99m)Tc-ECD brain perfusion SPECT findings.
Topics: Age of Onset; Amino Acid Substitution; Brain; Cerebrovascular Circulation; Disease Progression; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glycopeptides; Humans; Isoleucine; Male; Middle Aged; Mutation; Organotechnetium Compounds; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor); Serine; Siblings; Tomography, Emission-Computed, Single-Photon | 2010 |
Impact of the Asp299Gly polymorphism in the toll-like receptor 4 (tlr-4) gene on disease course of multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Cells, Cultured; Cytokines; Disease Progression; Germany; Glycine; Humans; Isoleucine; Membrane Glycoproteins; Middle Aged; Multiple Sclerosis; Polymorphism, Genetic; Receptors, Cell Surface; T-Lymphocytes, Regulatory; Threonine; Toll-Like Receptor 4; Toll-Like Receptors | 2005 |
Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Disease Progression; Female; Genotype; Glutathione Transferase; Hemochromatosis; Hepatitis C, Chronic; Humans; Isoleucine; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Prognosis; Valine | 2005 |
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.
Topics: Alleles; Aurora Kinase A; Aurora Kinases; Case-Control Studies; Disease Progression; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Isoleucine; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Risk; Stomach Neoplasms; Valine | 2006 |
The V118I mutation as a marker of advanced HIV infection and disease progression.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Disease Progression; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Logistic Models; Male; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Risk Assessment; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Failure; Valine | 2007 |
A novel mitochondrial tRNA isoleucine gene mutation causing chronic progressive external ophthalmoplegia.
Topics: Adult; Chronic Disease; Cytochrome-c Oxidase Deficiency; Disease Progression; Electron Transport Complex IV; Female; Humans; Isoleucine; Muscle Fibers, Skeletal; Muscle, Skeletal; Ophthalmoplegia; Point Mutation; RNA; RNA, Mitochondrial; RNA, Transfer | 1997 |
Role of CCR2 genotype in the clinical course of syncytium-inducing (SI) or non-SI human immunodeficiency virus type 1 infection and in the time to conversion to SI virus variants.
Topics: Cells, Cultured; Confidence Intervals; Disease Progression; Genetic Variation; Genotype; Giant Cells; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Isoleucine; Leukocytes, Mononuclear; Male; Point Mutation; Proportional Hazards Models; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Time Factors; Valine | 1998 |
Chemokine control of HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemokine CCL2; Chemokine CXCL12; Chemokines, CXC; Dimerization; Disease Progression; HIV Infections; HIV-1; Humans; Isoleucine; Point Mutation; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Cytokine; Valine | 1999 |
Progressive infantile neurodegeneration caused by 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: a novel inborn error of branched-chain fatty acid and isoleucine metabolism.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Disease Progression; Fatty Acids; Hemophilia A; Humans; Infant, Newborn; Intellectual Disability; Isoleucine; Lipid Metabolism, Inborn Errors; Male; Mitochondria; Neurodegenerative Diseases; Oxidation-Reduction; Psychomotor Agitation; Seizures | 2000 |