isoguvacine has been researched along with Alzheimer Disease in 1 studies
isoguvacine: A GABA agonist; RN given refers to parent cpd; structure
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, DC | 1 |
| Penney, JB | 1 |
| Young, AB | 1 |
1 other study available for isoguvacine and Alzheimer Disease
| Article | Year |
|---|---|
Cortical GABAB and GABAA receptors in Alzheimer's disease: a quantitative autoradiographic study.
Topics: Aged; Alzheimer Disease; Animals; Autoradiography; Baclofen; Binding, Competitive; Frontal Lobe; Hum | 1987 |