Page last updated: 2024-11-08

isoflurophate and Pregnancy

isoflurophate has been researched along with Pregnancy in 27 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"4-methylumbelliferylguanidinobenzoate (MUGB) reactivity in plasma from patients with cystic fibrosis and in amniotic fluid from pregnancies leading to children with cystic fibrosis, has been reported to be significantly decreased."7.66A serine protease activity of human serum albumin towards 4-methylumbelliferyl-guanidinobenzoate (MUGB) and diisopropyl fluorophosphate (DEP): implications for the use of MUGB reactivity in amniotic fluid in prenatal diagnosis of cystic fibrosis. ( Schwartz, M, 1982)
"4-methylumbelliferylguanidinobenzoate (MUGB) reactivity in plasma from patients with cystic fibrosis and in amniotic fluid from pregnancies leading to children with cystic fibrosis, has been reported to be significantly decreased."3.66A serine protease activity of human serum albumin towards 4-methylumbelliferyl-guanidinobenzoate (MUGB) and diisopropyl fluorophosphate (DEP): implications for the use of MUGB reactivity in amniotic fluid in prenatal diagnosis of cystic fibrosis. ( Schwartz, M, 1982)
"Oxytocin was inactivated by this enzyme preparation."1.26Purification and properties of oxytocinase (cystine amino-peptidase) from monkey placenta. ( Hayashi, M; Oshima, K, 1976)
"Three patients with thrombotic thrombocytopenic purpura (TTP) were treated by infusion of normal plasma with dramatic responses."1.26Presence of a platelet aggregating factor in the plasma of patients with thrombotic thrombocytopenic purpura (TTP) and its inhibition by normal plasma. ( Byrnes, JJ; Harkness, DR; Lian, EC; Nunez, R; Wallach, H, 1979)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199022 (81.48)18.7374
1990's3 (11.11)18.2507
2000's1 (3.70)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, J1
Naughton, SX1
Wulff, H1
Singh, V1
Beck, WD1
Magrane, J1
Thomas, B1
Kaidery, NA1
Hernandez, CM1
Terry, AV1
FREEDMAN, AM1
HIMWICH, HE1
HIRSCHBEIN, L1
ROZENCWAJ, GR1
BERLIN, NI1
MALLOV, S1
ALOUSI, AA1
Kofman, O1
Sher, T1
Levin, EG1
Schwartz, M1
Bläckberg, L1
Hernell, O1
Read, AP1
Fennell, SJ1
Donnai, D1
Harris, R1
Bisso, GM2
Meneguz, A1
Michalek, H2
Rowley, PT1
Ohlsson-Wilhelm, B1
Farley, B1
Kosciolek, B1
Little, BB1
Roe, DA1
Stettler, RW1
Bohman, VR1
Westfall, KL1
Sobhi, S1
Hayashi, M1
Oshima, K1
Holmberg, L1
Lecander, I1
Persson, B1
Astedt, B1
Lian, EC1
Harkness, DR1
Byrnes, JJ1
Wallach, H1
Nunez, R1
Kewitz, H1
Pleul, O1
Mann, E1
Balduini, W1
Lombardelli, G1
Peruzzi, G1
Cattabeni, F1
Hoskins, IA1
Katz, J1
Kadner, SS1
Young, BK1
Finlay, T1
Lee, FT1
Adams, JB1
Garton, AJ1
Yeaman, SJ1
Dalaker, K1
Pintor, A1
Fortuna, S1
Movat, HZ1
Steinberg, SG1
Habal, FM1
Ranadive, NS1
Cohen, T1
Cooney, DP1
Carretero, OA1
Houle, JA1
Bulmer, D1
Fisher, AW1
Fish, SA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ultrasound Guided Subclavian Vein Cannulation at Emergency Room , Success Rate and Incidence of Complications[NCT05107089]30 participants (Anticipated)Observational2021-11-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoflurophate and Pregnancy

ArticleYear
DETERMINATION OF RED BLOOD CELL LIFE SPAN.
    JAMA, 1964, Apr-27, Volume: 188

    Topics: Anemia; Carbon Isotopes; Chromium Isotopes; Erythrocytes; Glycine; Hemoglobins; Hemoglobins, Abnorma

1964

Other Studies

26 other studies available for isoflurophate and Pregnancy

ArticleYear
Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 356, Issue:3

    Topics: Animals; Axons; Biological Transport; Cell Membrane; Cells, Cultured; Cerebral Cortex; Cholinesteras

2016
The effect of size, sex and pregnancy on the lethality of diisopropyl fluorophosphate.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Fluorides; Isoflurophate; Phosphates; Phosphorus; Phosphorus Compounds; Phosphorus, Dietary; Pregnan

1948
[Effect of diisopropyfluorophosphate and pH in the association and dissociation of histones of the human placenta].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1960, Sep-26, Volume: 251

    Topics: Female; Histones; Humans; Isoflurophate; Placenta; Pregnancy

1960
LIPOPROTEIN LIPASE ACTIVITY OF RAT AND HUMAN PLACENTA.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Adipose Tissue; Animals; Female; Isoflurophate; Lipoprotein Lipase; Metabolism; Myocardium; Pharmaco

1965
Postnatal exposure to diisopropylfluorophosphate enhances discrimination learning in adult mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:5

    Topics: Animals; Cholinesterase Inhibitors; Discrimination Learning; Female; Isoflurophate; Male; Mice; Mice

2006
Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:22

    Topics: Cells, Cultured; Endothelium; Female; Fibrin; Humans; Isoflurophate; Molecular Weight; Plasminogen A

1983
A serine protease activity of human serum albumin towards 4-methylumbelliferyl-guanidinobenzoate (MUGB) and diisopropyl fluorophosphate (DEP): implications for the use of MUGB reactivity in amniotic fluid in prenatal diagnosis of cystic fibrosis.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Sep-15, Volume: 124, Issue:2

    Topics: Amniotic Fluid; Cystic Fibrosis; Endopeptidases; Female; Humans; Hymecromone; Isoflurophate; Pregnan

1982
The bile-salt-stimulated lipase in human milk. Purification and characterization.
    European journal of biochemistry, 1981, Volume: 116, Issue:2

    Topics: Amino Acids; Antibodies; Bile Acids and Salts; Enzyme Activation; Female; Humans; Immunoassay; Immun

1981
Amniotic fluid acetylcholinesterase: a retrospective and prospective study of the qualitative method.
    British journal of obstetrics and gynaecology, 1982, Volume: 89, Issue:2

    Topics: Acetylcholinesterase; Amniotic Fluid; Female; Humans; Isoflurophate; Neural Tube Defects; Pregnancy;

1982
Development factors affecting brain acetylcholinesterase inhibition and recovery in DFP-treated rats.
    Developmental neuroscience, 1982, Volume: 5, Issue:5-6

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Cholinesterase Inhibitors; Female; Fetal Diseases; Is

1982
Trypsin enhances erythropoiesis in vitro.
    The Journal of laboratory and clinical medicine, 1980, Volume: 96, Issue:3

    Topics: Adult; Bone Marrow Cells; Cell Survival; Chymotrypsin; Erythropoiesis; Female; Humans; Isoflurophate

1980
A new placental enzyme in the metabolism of cocaine: an in vitro animal model.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:5

    Topics: Animals; Biotransformation; Butyrylcholinesterase; Cocaine; Female; Isoflurophate; Microsomes; Model

1995
Purification and properties of oxytocinase (cystine amino-peptidase) from monkey placenta.
    Journal of biochemistry, 1976, Volume: 80, Issue:2

    Topics: Aluminum; Aminopeptidases; Animals; Biological Assay; Cations, Divalent; Cystinyl Aminopeptidase; Ed

1976
An inhibitor from placenta specifically binds urokinase and inhibits plasminogen activator released from ovarian carcinoma in tissue culture.
    Biochimica et biophysica acta, 1978, Nov-15, Volume: 544, Issue:1

    Topics: Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Female; Fibrin; Fibrinolysin; Humans; Immunodi

1978
Presence of a platelet aggregating factor in the plasma of patients with thrombotic thrombocytopenic purpura (TTP) and its inhibition by normal plasma.
    Blood, 1979, Volume: 53, Issue:2

    Topics: Adolescent; Aluminum Hydroxide; Blood Platelets; Female; Heparin; Hirudins; Humans; Isoantibodies; I

1979
Pre- and postnatal development and drug induced alterations of free and bound acetylcholine in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 298, Issue:2

    Topics: Acetylcholine; Aging; Animals; Anura; Atropine; Biological Assay; Brain; Brain Chemistry; Cholineste

1977
Cholinergic hyperinnervation in the cerebral cortex of microencephalic rats does not result in muscarinic receptor down-regulation or in alteration of receptor-stimulated phosphoinositide metabolism.
    Neurochemical research, 1992, Volume: 17, Issue:8

    Topics: Abnormalities, Drug-Induced; Acetylcholinesterase; Animals; Atropine; Brain; Cerebral Cortex; Down-R

1992
Use of esterase inhibitors and zone electrophoresis to define bacterial esterases in amniotic fluid.
    American journal of obstetrics and gynecology, 1992, Volume: 167, Issue:6

    Topics: Amniotic Fluid; Bacteria; Electrophoresis; Esterases; Female; Gram-Negative Bacteria; Gram-Positive

1992
Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones.
    Biochimica et biophysica acta, 1988, Nov-25, Volume: 963, Issue:2

    Topics: Androgens; Animals; Antibodies; Carboxylic Ester Hydrolases; Cattle; Cross Reactions; Estradiol; Fem

1988
Clotting factor VII during pregnancy, delivery and puerperium.
    British journal of obstetrics and gynaecology, 1986, Volume: 93, Issue:1

    Topics: Adult; Factor VII; Factor X; Female; Humans; Isoflurophate; Labor, Obstetric; Postpartum Period; Pre

1986
Effects of diisopropylfluorophosphate on brain cholinergic systems of rats at early developmental stages.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2

    Topics: Animals; Brain; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Cholinesterases; Female; Fet

1985
Demonstration of a kinin-generating enzyme in the lysosomes of human polymorphonuclear leukocytes.
    Laboratory investigation; a journal of technical methods and pathology, 1973, Volume: 29, Issue:6

    Topics: alpha 1-Antitrypsin; Animals; Aprotinin; Chromatography, Gel; Estrus; Female; Glucuronidase; Humans;

1973
Cyclic thrombocytopenia. Case report and review of literature.
    Scandinavian journal of haematology, 1974, Volume: 12, Issue:1

    Topics: Adult; Biopsy, Needle; Blood Cell Count; Blood Platelets; Blood Transfusion; Bone Marrow; Cell Survi

1974
A comparison of renin obtained from pregnant uterus and kidney of the dog.
    The American journal of physiology, 1970, Volume: 218, Issue:3

    Topics: Animals; Blood Pressure; Chemical Phenomena; Chemistry; Dogs; Edetic Acid; Female; Hydrogen-Ion Conc

1970
Studies on the characterization and localization of rat placental esterases.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1970, Volume: 18, Issue:10

    Topics: Acetates; Alcohols; Animals; Chloromercuribenzoates; Electrophoresis; Esterases; Esters; Female; His

1970
Organophosphorus cholinesterase inhibitors and fetal development.
    American journal of obstetrics and gynecology, 1966, Dec-15, Volume: 96, Issue:8

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Cholinesterase Inhibitors; Female; Fetal Death; Isofluro

1966