Page last updated: 2024-11-08

isoflurophate and Nerve Degeneration

isoflurophate has been researched along with Nerve Degeneration in 15 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Ataxia was evident with both materials, and the degree of peripheral neuropathy increased with higher doses of these agents."1.24Neurotoxic syndrome produced in chickens by a cyclic phosphate metabolite of tri-o-cresyl phosphate--a clinical and pathological study. ( BARON, RL; BENNETT, DR; CASIDA, JE, 1962)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's3 (20.00)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
González, EA1
Rindy, AC1
Guignet, MA1
Calsbeek, JJ1
Bruun, DA1
Dhir, A1
Andrew, P1
Saito, N1
Rowland, DJ1
Harvey, DJ1
Rogawski, MA1
Lein, PJ1
Putra, M1
Sharma, S1
Gage, M1
Gasser, G1
Hinojo-Perez, A1
Olson, A1
Gregory-Flores, A1
Puttachary, S1
Wang, C1
Anantharam, V1
Thippeswamy, T1
BARON, RL1
BENNETT, DR1
CASIDA, JE1
WOLMAN, M1
Kropp, TJ1
Glynn, P1
Richardson, RJ1
Drakontides, AB1
Baker, T1
Riker, WF1
Sprague, GL1
Sandvik, LL1
Bickford, AA1
Geula, C1
Mesulam, MM1
Kuo, CC1
Tokuno, H1
Bouldin, TW2
Cavanagh, JB2
Kreutzberg, GW1
Tóth, L1
Kaiya, H1
Forloni, GL1
Angeretti, N1
Rizzi, M1
Vezzani, A1
Pope, CN1
Chapman, ML1
Tanaka, D1
Padilla, S1
Ehrich, M1
Jortner, BS1
Gross, WB1
Rubino, A1
Bonavita, V1

Other Studies

15 other studies available for isoflurophate and Nerve Degeneration

ArticleYear
The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity.
    Archives of toxicology, 2020, Volume: 94, Issue:6

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Brain; Brain Waves; Cholinesterase Inhibitors; Conv

2020
Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.
    Neurobiology of disease, 2020, Volume: 133

    Topics: Amidines; Animals; Benzylamines; Brain; Disease Models, Animal; Enzyme Inhibitors; Isoflurophate; Ma

2020
Neurotoxic syndrome produced in chickens by a cyclic phosphate metabolite of tri-o-cresyl phosphate--a clinical and pathological study.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Animals; Ataxia; Axons; Chickens; Humans; Isoflurophate; Nerve Degeneration; Nervous System Diseases

1962
IN VITRO BREAKDOWN OF MYELIN.
    Annals of the New York Academy of Sciences, 1965, Mar-31, Volume: 122

    Topics: Animals; Demyelinating Diseases; Diphosphates; In Vitro Techniques; Isoflurophate; Mice; Myelin Shea

1965
The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss.
    Biochemistry, 2004, Mar-30, Volume: 43, Issue:12

    Topics: Amino Acid Sequence; Carboxylic Ester Hydrolases; Catalytic Domain; Enzyme Inhibitors; Enzyme Reacti

2004
A morphological study of the effect of glucocorticoid treatment on delayed organophosphorus neuropathy.
    Neurotoxicology, 1982, Volume: 3, Issue:4

    Topics: Animals; Axons; Cats; Female; Glucocorticoids; Isoflurophate; Male; Nerve Degeneration; Neuromuscula

1982
Time course for neurotoxic esterase inhibition in hens given multiple diisopropyl fluorophosphate injections.
    Neurotoxicology, 1981, Volume: 2, Issue:3

    Topics: Animals; Axons; Carboxylic Ester Hydrolases; Chickens; Female; Isoflurophate; Nerve Degeneration; Ne

1981
Postnatal development of cortical acetylcholinesterase-rich neurons in the rat brain: permanent and transient patterns.
    Experimental neurology, 1995, Volume: 134, Issue:2

    Topics: Acetylcholinesterase; Animals; Animals, Newborn; Cell Count; Cerebral Cortex; Female; Isoflurophate;

1995
Organophosphorous neuropathy. I. A teased-fiber study of the spatio-temporal spread of axonal degeneraion.
    The American journal of pathology, 1979, Volume: 94, Issue:2

    Topics: Animals; Axons; Cats; Female; Isoflurophate; Laryngeal Nerves; Male; Nerve Degeneration; Nerve Fiber

1979
Organophosphorous neuropathy. II. A fine-structural study of the early stages of axonal degeneration.
    The American journal of pathology, 1979, Volume: 94, Issue:2

    Topics: Animals; Axons; Cats; Isoflurophate; Laryngeal Nerves; Nerve Degeneration; Nerve Fibers; Nervous Sys

1979
Acetylcholinesterase as a marker for dendritic transport and dendritic secretion.
    Advances in neurology, 1975, Volume: 12

    Topics: Acetylcholinesterase; Animals; Basement Membrane; Brain; Capillaries; Cats; Dendrites; Endoplasmic R

1975
Chronic infusion of quinolinic acid in rat striatum: effects on discrete neuronal populations.
    Journal of the neurological sciences, 1992, Volume: 108, Issue:2

    Topics: Acetylcholinesterase; Animals; Atropine Derivatives; Cell Division; Corpus Striatum; Histocytochemis

1992
Phenylmethylsulfonyl fluoride alters sensitivity to organophosphorus-induced delayed neurotoxicity in developing animals.
    Neurotoxicology, 1992,Summer, Volume: 13, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Drug Synergism; Female; Isoflurophate; Nerve Degener

1992
Absence of a protective effect of corticosterone on 0-0-diisopropyl phosphorofluoridate (DFP) induced delayed neurotoxicity in chickens.
    Neurotoxicology, 1985,Spring, Volume: 6, Issue:1

    Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Cholinesterase Inhibitors; Corticosterone; Is

1985
[Metabolic organization of the normal and degenerating peripheral nerve].
    Rivista di patologia nervosa e mentale, 1965, Volume: 86, Issue:2

    Topics: Animals; In Vitro Techniques; Isocitrate Dehydrogenase; Isoenzymes; Isoflurophate; L-Lactate Dehydro

1965