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isoflurophate and Motor Neuron Disease

isoflurophate has been researched along with Motor Neuron Disease in 1 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hein, ND1
Stuckey, JA1
Rainier, SR1
Fink, JK1
Richardson, RJ1

Other Studies

1 other study available for isoflurophate and Motor Neuron Disease

ArticleYear
Constructs of human neuropathy target esterase catalytic domain containing mutations related to motor neuron disease have altered enzymatic properties.
    Toxicology letters, 2010, Jul-01, Volume: 196, Issue:2

    Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Chlorpyrifos; Enzyme Inhibitors; Humans; Hydrolysis;

2010