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isoflurophate and Fasciculation

isoflurophate has been researched along with Fasciculation in 3 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to evaluate the possible preventive effects of acute treatment with reversible acetylcholinesterase inhibitor galantamine against the signs of cholinergic toxic syndrome provoked by diisopropylfluorophosphate, such as hypothermia, muscular fasciculations, oral dyskinesia and decreased locomotor performance in a rat model of intoxication."3.79Galantamine as a preventive of diisopropylphosphorofluoridate toxicity effects in rat brain. ( Pregelj, P; Saghafi, MM; Živin, M, 2013)
"Pronounced muscle fasciculations and muscle fiber necrosis were seen when acetylcholinesterase (AChE) activity was reduced to less than 30% of control."1.31Spin trapping agent phenyl-N-tert-butylnitrone prevents diisopropylphosphorofluoridate-induced excitotoxicity in skeletal muscle of the rat. ( Dettbarn, WD; Hustedt, E; Milatovic, D; Zivin, M, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saghafi, MM1
Živin, M2
Pregelj, P1
Yang, ZP1
Morrow, J1
Wu, A1
Roberts, LJ1
Dettbarn, WD2
Milatovic, D1
Hustedt, E1

Other Studies

3 other studies available for isoflurophate and Fasciculation

ArticleYear
Galantamine as a preventive of diisopropylphosphorofluoridate toxicity effects in rat brain.
    Folia biologica, 2013, Volume: 59, Issue:1

    Topics: Acetylcholinesterase; Animals; Body Temperature; Brain; Fasciculation; Galantamine; Gene Expression

2013
Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo.
    Biochemical pharmacology, 1996, Jul-26, Volume: 52, Issue:2

    Topics: Animals; Cholinesterase Inhibitors; Chromans; Dinoprost; Fasciculation; Isoflurophate; Lipid Peroxid

1996
Spin trapping agent phenyl-N-tert-butylnitrone prevents diisopropylphosphorofluoridate-induced excitotoxicity in skeletal muscle of the rat.
    Neuroscience letters, 2000, Jan-07, Volume: 278, Issue:1-2

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cyclic N-Oxides; Excitatory Amin

2000