Page last updated: 2024-08-17

isoflurophate and Disease Models, Animal

isoflurophate has been researched along with Disease Models, Animal in 39 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19905 (12.82)18.7374
1990's6 (15.38)18.2507
2000's1 (2.56)29.6817
2010's14 (35.90)24.3611
2020's13 (33.33)2.80

Authors

AuthorsStudies
Bruun, DA; Calsbeek, JJ; Copping, N; Dawson, ME; González, EA; Guignet, MA; Harvey, DJ; Lein, PJ; MacMahon, JA; Saito, NH; Silverman, JL; Yu, AJ1
Abreu-Melon, J; Dingledine, R; Rojas, A; Wang, S1
Anantharam, V; Gage, M; Gardner, C; Gasser, G; Putra, M; Sharma, S; Thippeswamy, T1
Gage, M; Golden, M; Putra, M; Sharma, S; Thippeswamy, T1
Dingledine, R; Glover, A; Rojas, A; Wang, J1
Auvin, S; Dal Bo, G; Dupuis, N; Enderlin, J; Igert, A; Nachon, F1
Ashbrook, DG; Gao, J; Jones, BC; Lu, L; Miller, DB; O'Callaghan, JP; Starlard-Davenport, A; Williams, RW; Xu, F; Zhao, W1
Bealer, SL; Dudek, FE; Smolik, M; Spampanato, J1
Hester, K; Liu, J; Pope, C1
Abreu-Melon, J; Dingledine, R; McCarren, HS; McDonough, JH; Rojas, A; Wang, J; Wang, S; Wang, W1
Calderazzo, S; Kelly, KA; Killiany, RJ; Koo, BB; Michalovicz, LT; O'Callaghan, JP; Sullivan, K1
Garbow, JR; Harvey, DJ; Hobson, BA; Lein, PJ; Rowland, DJ; Supasai, S1
Day, BJ; Huang, J; Liang, LP; McElroy, P; Patel, M; Pearson-Smith, JN1
Dingledine, R; Ganesh, T; Rojas, A; Wang, J; Wang, W1
Bruun, DA; Guignet, M; Harvey, DJ; Lein, PJ1
Blair, RE; Deshpande, LS; Phillips, KF; Santos, E1
Bruun, DA; Dhakal, K; Dhir, A; Flannery, BM; Guignet, M; Harvey, DJ; Hobson, BA; Lein, PJ; Li, S; Rogawski, MA; Silverman, JL; Wahab, A; Zolkowska, D1
Anantharam, V; Gage, M; Gasser, G; Gregory-Flores, A; Hinojo-Perez, A; Olson, A; Putra, M; Puttachary, S; Sharma, S; Thippeswamy, T; Wang, C1
Bealer, SL; Dudek, FE; Pouliot, W; Roach, B; Spampanato, J1
Dingledine, R; Ganesh, T; Gueorguieva, P; Lelutiu, N; Rojas, A1
Kelly, KA; Lasley, SM; Locker, AR; Miller, DB; O'Callaghan, JP1
Bruun, DA; Distel, TJ; Ford, BD; Ford, GD; Gates, AS; Lein, PJ; Li, Y; Liu, C; Stovall, KC; Surles-Zeigler, MC; Tewolde, T; White, TE1
Deshpande, LS; Phillips, KF1
Bruun, DA; Hammock, BD; Lein, PJ; Pessah, IN; Rogawski, MA; Tancredi, DJ; Wulff, H; Zolkowska, D1
Dingledine, R; Ganesh, T; Manji, Z; O'neill, T; Rojas, A1
Aschner, M; Gupta, RC; Milatovic, D; Zaja-Milatovic, S1
Dori, A; Duek, O; Kofman, O; Lin, T; Livneh, U; Oriel, S1
Auta, J; Davis, JM; Gocel, J; Guidotti, A; Kadriu, B; Larson, J; Nambiar, MP1
Bito, LZ; Bunke, A1
Wickelgren, I1
Buccafusco, JJ; Zhang, LC1
Albuquerque, EX; Copio, DS; Eldefrawi, AT; Eldefrawi, ME; Oliveira, AC1
Carboni, D; Dyer, K; Ehrich, M; Jortner, BS1
Dyer, KR; Ehrich, M; Jortner, BS; Shell, LG1
Overstreet, DH; Pucilowski, O; Schiller, GD; Wienicke, C1
Aulerich, RJ; Bursian, SJ; Lehning, EJ; Tanaka, D1
Overstreet, DH1
Baker, WW; Lalley, PM; Rossi, GV1
Bronson, LJ; Lazar, M1

Reviews

3 review(s) available for isoflurophate and Disease Models, Animal

ArticleYear
A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition.
    Neurobiology of disease, 2020, Volume: 133

    Topics: Animals; Cholinesterase Inhibitors; Disease Models, Animal; Indoles; Isoflurophate; Organophosphate Poisoning; Rats; Receptors, Prostaglandin E, EP2 Subtype; Status Epilepticus

2020
Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication.
    Neurobiology of disease, 2020, Volume: 133

    Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Inflammation; Isoflurophate; Male; Neurotoxicity Syndromes; Organophosphate Poisoning; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus

2020
Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents.
    Annals of the New York Academy of Sciences, 2016, Volume: 1378, Issue:1

    Topics: Animals; Anticonvulsants; Brain; Bridged-Ring Compounds; Cholinesterase Inhibitors; Disease Models, Animal; Humans; Isoflurophate; Neuroprotective Agents; Organophosphate Poisoning; Seizures; Treatment Outcome

2016

Other Studies

36 other study(ies) available for isoflurophate and Disease Models, Animal

ArticleYear
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate.
    Neurotoxicology, 2021, Volume: 87

    Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Electroencephalography; Female; Isoflurophate; Male; Mice; Mice, Inbred C57BL; Nesting Behavior; Neuroinflammatory Diseases; Open Field Test; Status Epilepticus

2021
Time-dependent neuropathology in rats following organophosphate-induced status epilepticus.
    Neurotoxicology, 2022, Volume: 91

    Topics: Animals; Brain; Disease Models, Animal; Isoflurophate; Organophosphate Poisoning; Organophosphates; Rats; Rats, Sprague-Dawley; Status Epilepticus

2022
Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model.
    Annals of the New York Academy of Sciences, 2020, Volume: 1479, Issue:1

    Topics: Acetophenones; Animals; Biphenyl Compounds; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; Isoflurophate; Male; NADPH Oxidases; Nerve Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Status Epilepticus

2020
Sex as a biological variable in the rat model of diisopropylfluorophosphate-induced long-term neurotoxicity.
    Annals of the New York Academy of Sciences, 2020, Volume: 1479, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Female; Isoflurophate; Male; Neurotoxicity Syndromes; Rats; Sex Characteristics; Status Epilepticus

2020
Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats.
    Neurobiology of disease, 2020, Volume: 140

    Topics: Acetylcholinesterase; Animals; Brain Injuries; Diazepam; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Hippocampus; Isoflurophate; Male; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Urethane

2020
Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure.
    Epilepsia, 2020, Volume: 61, Issue:6

    Topics: Animals; Brain; Brain Injuries; Cholinesterase Inhibitors; Disease Models, Animal; Electrocorticography; Isoflurophate; Male; Mice; Organophosphates; Seizures; Status Epilepticus

2020
Genome-wide transcriptome architecture in a mouse model of Gulf War Illness.
    Brain, behavior, and immunity, 2020, Volume: 89

    Topics: Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Gulf War; Isoflurophate; Mice; Persian Gulf Syndrome; Transcriptome

2020
Delayed Adjunctive Treatment of Organophosphate-Induced Status Epilepticus in Rats with Phenobarbital, Memantine, or Dexmedetomidine.
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 375, Issue:1

    Topics: Animals; Anticonvulsants; Brain; Cell Death; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Isoflurophate; Male; Memantine; Neurons; Phenobarbital; Prohibitins; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time-to-Treatment; Treatment Outcome

2020
Dose- and time-related effects of acute diisopropylfluorophosphate intoxication on forced swim behavior and sucrose preference in rats.
    Neurotoxicology, 2021, Volume: 82

    Topics: Anhedonia; Animals; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Isoflurophate; Male; Rats; Rats, Sprague-Dawley; Sucrose; Swimming

2021
Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman.
    Neurotoxicology, 2021, Volume: 83

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Waves; Cell Death; Cyclooxygenase 2; Disease Models, Animal; Electroencephalography; Encephalitis; Gliosis; Isoflurophate; Male; Rats, Sprague-Dawley; Soman; Status Epilepticus; Time Factors; Weight Loss

2021
Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness.
    Brain, behavior, and immunity, 2018, Volume: 67

    Topics: Animals; Brain; Corticosterone; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Encephalitis; Isoflurophate; Male; Persian Gulf Syndrome; Rats, Sprague-Dawley; Stress, Physiological

2018
A magnetic resonance imaging study of early brain injury in a rat model of acute DFP intoxication.
    Neurotoxicology, 2018, Volume: 66

    Topics: Animals; Brain Injuries; Disease Models, Animal; Isoflurophate; Magnetic Resonance Imaging; Male; Rats, Sprague-Dawley; Status Epilepticus

2018
Neuroprotective Effects of AEOL10150 in a Rat Organophosphate Model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2018, 04-01, Volume: 162, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Isoflurophate; Male; Metalloporphyrins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Sprague-Dawley

2018
Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
    Neurotoxicology, 2019, Volume: 73

    Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; GPI-Linked Proteins; Isoflurophate; Male; Neurotoxicity Syndromes; Organophosphate Poisoning; Pyridostigmine Bromide; Rats, Sprague-Dawley; Seizures; Time Factors

2019
Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, 06-01, Volume: 169, Issue:2

    Topics: Animals; Calcium; Disease Models, Animal; Hippocampus; Isoflurophate; Levetiracetam; Male; Maze Learning; Persian Gulf Syndrome; Rats; Rats, Sprague-Dawley

2019
Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.
    Neurobiology of disease, 2020, Volume: 133

    Topics: Amidines; Animals; Benzylamines; Brain; Disease Models, Animal; Enzyme Inhibitors; Isoflurophate; Male; Nerve Agents; Nerve Degeneration; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley

2020
Antiseizure and neuroprotective effects of delayed treatment with midazolam in a rodent model of organophosphate exposure.
    Epilepsia, 2019, Volume: 60, Issue:7

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Isoflurophate; Male; Midazolam; Neuroprotective Agents; Organophosphate Poisoning; Rats; Rats, Sprague-Dawley; Seizures

2019
Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus.
    Neuropharmacology, 2015, Volume: 93

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Body Weight; Chemokines; Cholinesterase Inhibitors; Cyclooxygenase 2; Disease Models, Animal; Gliosis; Hippocampus; Indoles; Isoflurophate; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP2 Subtype; Recovery of Function; Status Epilepticus; Time Factors

2015
Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness.
    Journal of neurochemistry, 2015, Volume: 133, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Chemical Warfare Agents; Cholinesterase Inhibitors; Corticosterone; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Insect Repellents; Isoflurophate; Male; Mice; Mice, Inbred C57BL; Minocycline; Persian Gulf Syndrome

2015
Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury.
    Journal of neuroinflammation, 2015, Apr-02, Volume: 12

    Topics: Animals; Brain; Cholinesterase Inhibitors; Cytokines; Disease Models, Animal; Encephalitis; Gene Expression Profiling; Gene Expression Regulation; Injections, Intra-Arterial; Isoflurophate; Male; Microglia; Neuregulin-1; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; RNA, Messenger

2015
Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness.
    Neurotoxicology, 2016, Volume: 52

    Topics: Anhedonia; Animals; Anxiety; Depression; Disease Models, Animal; Hippocampus; Isoflurophate; Male; Memory Disorders; Organophosphates; Persian Gulf Syndrome; Rats

2016
Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats.
    Neuropharmacology, 2016, Volume: 110, Issue:Pt A

    Topics: Animals; Anxiety; Brain; Discrimination, Psychological; Disease Models, Animal; Electroencephalography; Exploratory Behavior; Indoles; Isoflurophate; Male; Memory Disorders; Nootropic Agents; Random Allocation; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP2 Subtype; Recognition, Psychology; Status Epilepticus

2016
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist.
    Toxicology and applied pharmacology, 2009, Oct-15, Volume: 240, Issue:2

    Topics: Animals; Antioxidants; Biomarkers; Brain; Cholinesterase Inhibitors; Cyclic N-Oxides; Disease Models, Animal; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Isoflurophate; Lipid Peroxidation; Male; Memantine; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors; Vitamin A

2009
Acetylcholinesterase inhibitor pretreatment alters stress-induced expression of acetylcholinesterase transcripts in the mouse brain.
    Neuroscience, 2011, Jun-02, Volume: 183

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gene Expression Regulation, Enzymologic; Isoflurophate; Maze Learning; Mice; Mice, Inbred C57BL; Reaction Time; RNA, Messenger; Species Specificity; Statistics as Topic; Stress, Psychological

2011
Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage.
    Neuropharmacology, 2011, Volume: 61, Issue:8

    Topics: Animals; Anticonvulsants; Benzodiazepines; Cholinesterase Inhibitors; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoresceins; Imidazoles; Isoflurophate; Male; Neurons; Neuroprotective Agents; Organic Chemicals; Rats; Rats, Inbred F344; Seizures; Statistics, Nonparametric

2011
Gradual increase in the sensitivity of extraocular muscles to acetylcholine during topical treatment of rabbit eyes with isoflurophate.
    American journal of ophthalmology, 1981, Volume: 92, Issue:2

    Topics: Acetylcholine; Animals; Disease Models, Animal; Drug Synergism; Esotropia; Eye Diseases; Glaucoma; Isoflurophate; Oculomotor Muscles; Rabbits

1981
Rat model for Gulf War syndrome?
    Science (New York, N.Y.), 1997, Nov-21, Volume: 278, Issue:5342

    Topics: Animals; Disease Models, Animal; Hippocampus; Humans; Isoflurophate; Maze Learning; Military Personnel; Nicotinic Antagonists; Persian Gulf Syndrome; Rats; Receptors, Nicotinic

1997
Prevention of morphine-induced muscarinic (M2) receptor adaptation suppresses the expression of withdrawal symptoms.
    Brain research, 1998, Aug-24, Volume: 803, Issue:1-2

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Disease Models, Animal; Infusions, Intravenous; Injections, Subcutaneous; Isoflurophate; Male; Morphine; Morphine Dependence; Naloxone; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptors, Muscarinic; Substance Withdrawal Syndrome; Vasomotor System

1998
Myasthenia gravis animal model: quantitative analysis of the efficiency of pre- and postjunctional regions of intercostal muscles in rabbits immunized with Torpedo acetylcholine receptor.
    Experimental neurology, 1979, Volume: 66, Issue:1

    Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Electric Organ; Isoflurophate; Motor Endplate; Myasthenia Gravis; Neuromuscular Junction; Rabbits; Receptors, Cholinergic; Synaptic Transmission

1979
Comparative evolution of mipafox-induced delayed neuropathy in rats and hens.
    Neurotoxicology, 1992,Winter, Volume: 13, Issue:4

    Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Disease Models, Animal; Female; Isoflurophate; Male; Nervous System Diseases; Rats; Species Specificity

1992
Comparative dose-response studies of organophosphorus ester-induced delayed neuropathy in rats and hens administered mipafox.
    Neurotoxicology, 1992,Winter, Volume: 13, Issue:4

    Topics: Animals; Carboxylic Ester Hydrolases; Chickens; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Isoflurophate; Male; Microscopy, Electron; Nervous System Diseases; Rats; Species Specificity

1992
Immobility-reducing effects of antidepressants in a genetic animal model of depression.
    Brain research bulletin, 1992, Volume: 28, Issue:5

    Topics: Animals; Antidepressive Agents; Depression; Depression, Chemical; Desipramine; Disease Models, Animal; Imipramine; Isoflurophate; Motor Activity; Rats; Rats, Inbred Strains; Swimming

1992
Delayed neurotoxic effects of bis (1-methylethyl) phosphorofluoridate (DFP) in the European ferret: a possible mammalian model for organophosphorus-induced delayed neurotoxicity.
    Neurotoxicology, 1991,Summer, Volume: 12, Issue:2

    Topics: Animals; Carboxylic Ester Hydrolases; Central Nervous System; Cerebellum; Cholinesterases; Disease Models, Animal; Female; Ferrets; Isoflurophate; Male; Medulla Oblongata; Organophosphorus Compounds; Silver Staining; Spinal Cord; Time Factors

1991
Selective breeding for increased cholinergic function: development of a new animal model of depression.
    Biological psychiatry, 1986, Volume: 21, Issue:1

    Topics: Animals; Arecoline; Breeding; Depression; Depressive Disorder; Disease Models, Animal; Electroshock; Isoflurophate; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Stress, Physiological

1986
Analysis of local cholinergic tremor mechanisms following selective neurochemical lesions.
    Experimental neurology, 1970, Volume: 27, Issue:2

    Topics: Acetylcholine; Animals; Basal Ganglia; Brain; Carbachol; Cats; Cholinesterase Inhibitors; Disease Models, Animal; Dopamine; Drug Antagonism; Drug Synergism; Epinephrine; Hemicholinium 3; Isoflurophate; Ketones; Male; Oximes; Pentobarbital; Physostigmine; Pralidoxime Compounds; Receptors, Drug; Scopolamine; Tremor

1970
The role of corneal exposure in cataract formation in DFP-treated guinea pigs.
    American journal of ophthalmology, 1970, Volume: 69, Issue:5

    Topics: Animals; Cataract; Corneal Opacity; Disease Models, Animal; Guinea Pigs; Isoflurophate; Lens, Crystalline

1970