isoflurophate has been researched along with Cognition Disorders in 1 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To avoid these treatment complications but safely protect against DFP-induced seizures and other CNS toxicity, we adopted the strategy of administering mice with (i) small doses of huperzine A (HUP), a reversible and long-lasting (half-life approximately 5 h) inhibitor of AChE, and (ii) imidazenil (IMI), a potent positive allosteric modulator of GABA action selective for alpha(5)-containing GABA(A) receptors." | 3.74 | The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. ( Auta, J; Costa, E; Guidotti, A; Kadriu, B; Kozikowski, AP; Pibiri, F; Pinna, G, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pibiri, F | 1 |
| Kozikowski, AP | 1 |
| Pinna, G | 1 |
| Auta, J | 1 |
| Kadriu, B | 1 |
| Costa, E | 1 |
| Guidotti, A | 1 |
1 other study available for isoflurophate and Cognition Disorders
| Article | Year |
|---|---|
The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice.
Topics: Alkaloids; Animals; Benzodiazepines; Cognition Disorders; Drug Therapy, Combination; Imidazoles; Iso | 2008 |