isoflurophate has been researched along with Brain Edema in 2 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats were observed for seizure activity for 2 h, survivors were killed 24 h later and edema was measured in samples from parietal and piriform cortices, dorsal thalmus, and hippocampus." | 1.28 | Effect of LiCl pretreatment on cholinomimetic-induced seizures and seizure-induced brain edema in rats. ( Nelson, SR; Padzernik, TL; Terry, JB, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, SY | 1 |
| Casida, JE | 1 |
| Terry, JB | 1 |
| Padzernik, TL | 1 |
| Nelson, SR | 1 |
2 other studies available for isoflurophate and Brain Edema
| Article | Year |
|---|---|
Subacute neurotoxicity induced in mice by potent organophosphorus neuropathy target esterase inhibitors.
Topics: Animals; Ataxia; Biomarkers; Brain; Brain Edema; Carboxylic Ester Hydrolases; Cholinesterase Inhibit | 1996 |
Effect of LiCl pretreatment on cholinomimetic-induced seizures and seizure-induced brain edema in rats.
Topics: Animals; Brain; Brain Edema; Chlorides; Isoflurophate; Lithium; Lithium Chloride; Male; Organ Specif | 1990 |