isoflurophate has been researched along with Brain Disorders in 4 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Low-dose DFP caused minimal ataxia and increased frequency of axonal lesions in dorsal and lateral cervical spinal cord, ventral lumbar spinal cord, and inferior cerebellar peduncles (ICP) compared to control." | 1.30 | Potentiation of organophosphorus compound-induced delayed neurotoxicity (OPIDN) in the central and peripheral nervous system of the adult hen: distribution of axonal lesions. ( Randall, JC; Richardson, RJ; Yano, BL, 1997) |
| " The site was found to be present and capable of binding di-isopropyl phosphorofluoridate in vitro in brain samples taken from either normal hens or those dosed with organophosphorus esterase inhibitors that are not neurotoxic." | 1.25 | A phosphorylation site in brain and the delayed neurotoxic effect of some organophosphorus compounds. ( Johnson, MK, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Supasai, S | 1 |
| González, EA | 1 |
| Rowland, DJ | 1 |
| Hobson, B | 1 |
| Bruun, DA | 1 |
| Guignet, MA | 1 |
| Soares, S | 1 |
| Singh, V | 1 |
| Wulff, H | 1 |
| Saito, N | 1 |
| Harvey, DJ | 1 |
| Lein, PJ | 1 |
| Brewer, KL | 1 |
| Troendle, MM | 1 |
| Pekman, L | 1 |
| Meggs, WJ | 1 |
| Randall, JC | 1 |
| Yano, BL | 1 |
| Richardson, RJ | 1 |
| Johnson, MK | 1 |
4 other studies available for isoflurophate and Brain Disorders
| Article | Year |
|---|---|
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Topics: Animals; Brain Diseases; Cholinesterase Inhibitors; Diazepam; GABA Modulators; Gliosis; Isoflurophat | 2020 |
Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate.
Topics: Animals; Brain Diseases; Central Nervous System Agents; Cholinesterase Inhibitors; Female; Injection | 2013 |
Potentiation of organophosphorus compound-induced delayed neurotoxicity (OPIDN) in the central and peripheral nervous system of the adult hen: distribution of axonal lesions.
Topics: Animals; Ataxia; Axons; Biomarkers; Brain; Brain Diseases; Carboxylic Ester Hydrolases; Chickens; Dr | 1997 |
A phosphorylation site in brain and the delayed neurotoxic effect of some organophosphorus compounds.
Topics: Animals; Brain Chemistry; Brain Diseases; Chickens; Cholinesterases; Esterases; In Vitro Techniques; | 1969 |