Page last updated: 2024-11-08

isoflurophate and Brain Disorders

isoflurophate has been researched along with Brain Disorders in 4 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Research Excerpts

ExcerptRelevanceReference
"Low-dose DFP caused minimal ataxia and increased frequency of axonal lesions in dorsal and lateral cervical spinal cord, ventral lumbar spinal cord, and inferior cerebellar peduncles (ICP) compared to control."1.30Potentiation of organophosphorus compound-induced delayed neurotoxicity (OPIDN) in the central and peripheral nervous system of the adult hen: distribution of axonal lesions. ( Randall, JC; Richardson, RJ; Yano, BL, 1997)
" The site was found to be present and capable of binding di-isopropyl phosphorofluoridate in vitro in brain samples taken from either normal hens or those dosed with organophosphorus esterase inhibitors that are not neurotoxic."1.25A phosphorylation site in brain and the delayed neurotoxic effect of some organophosphorus compounds. ( Johnson, MK, 1969)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Supasai, S1
González, EA1
Rowland, DJ1
Hobson, B1
Bruun, DA1
Guignet, MA1
Soares, S1
Singh, V1
Wulff, H1
Saito, N1
Harvey, DJ1
Lein, PJ1
Brewer, KL1
Troendle, MM1
Pekman, L1
Meggs, WJ1
Randall, JC1
Yano, BL1
Richardson, RJ1
Johnson, MK1

Other Studies

4 other studies available for isoflurophate and Brain Disorders

ArticleYear
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
    European journal of pharmacology, 2020, Nov-05, Volume: 886

    Topics: Animals; Brain Diseases; Cholinesterase Inhibitors; Diazepam; GABA Modulators; Gliosis; Isoflurophat

2020
Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:4

    Topics: Animals; Brain Diseases; Central Nervous System Agents; Cholinesterase Inhibitors; Female; Injection

2013
Potentiation of organophosphorus compound-induced delayed neurotoxicity (OPIDN) in the central and peripheral nervous system of the adult hen: distribution of axonal lesions.
    Journal of toxicology and environmental health, 1997, Aug-29, Volume: 51, Issue:6

    Topics: Animals; Ataxia; Axons; Biomarkers; Brain; Brain Diseases; Carboxylic Ester Hydrolases; Chickens; Dr

1997
A phosphorylation site in brain and the delayed neurotoxic effect of some organophosphorus compounds.
    The Biochemical journal, 1969, Volume: 111, Issue:4

    Topics: Animals; Brain Chemistry; Brain Diseases; Chickens; Cholinesterases; Esterases; In Vitro Techniques;

1969