Page last updated: 2024-11-08

isoflurophate and Anesthesia

isoflurophate has been researched along with Anesthesia in 7 studies

Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Clofibric acid has been shown previously to undergo a futile cycle in which its net clearance is dependent upon conjugation to form an acyl (ester) glucuronide and a combination of hydrolysis of the conjugate and its renal clearance."1.27Diisopropylfluorophosphate increases clofibric acid clearance: supporting evidence for a futile cycle. ( Meffin, PJ; Rowe, BJ, 1984)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GREEN, VA1
Rosić, N1
Milosević, MP1
Rowe, BJ1
Meffin, PJ1
Testylier, G1
Maalouf, M1
Butt, AE1
Miasnikov, AA1
Dykes, RW1
Dross, K2
Kewitz, H2
Marynen-de Preter, L1

Other Studies

7 other studies available for isoflurophate and Anesthesia

ArticleYear
ALTERATIONS IN THE ACTIVITY OF PENTOTHAL, PHENOBARBITAL, PENTYLENETETRAZOL, AND STRYCHNINE BY CHOLINESTERASE INHIBITORS.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Acetylcholine; Anesthesia; Atropine; Cholinesterase Inhibitors; Isoflurophate; Mice; Neostigmine; Pe

1964
The relationship between cholinesterase activity and brain permeability to barbitone.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Anesthesia; Animals; Barbiturates; Brain; Cholinesterase Inhibitors; Cholinesterases; Echothiophate

1967
Diisopropylfluorophosphate increases clofibric acid clearance: supporting evidence for a futile cycle.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Clofibrate; Clofibric Acid; Hydrolysis; Isoflurophate; Male; Me

1984
Evidence for homeostatic adjustments of rat somatosensory cortical neurons to changes in extracellular acetylcholine concentrations produced by iontophoretic administration of acetylcholine and by systemic diisopropylfluorophosphate treatment.
    Neuroscience, 1999, Volume: 91, Issue:3

    Topics: Acetylcholine; Anesthesia; Animals; Cholinesterase Inhibitors; Electroencephalography; Electromyogra

1999
[Incorporation of choline into acetylcholine during narcosis and in DFP-poisoning].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Acetylcholine; Acetylcholinesterase; Anesthesia; Animals; Brain; Carbon Isotopes; Choline; Hexobarbi

1967
[Concentration of acetylcholine, choline and glycerylphosphorylcholine in the brain during anesthesia and in DFP poisoning].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Acetylcholine; Anesthesia; Animals; Brain; Choline; Depression, Chemical; Glycerylphosphorylcholine;

1968
[Ophthalmological use of organophosphates and their effects on the enzyme system].
    Acta anaesthesiologica Belgica, 1972, Volume: 23, Issue:2

    Topics: Acetylcholinesterase; Anesthesia; Child; Cholinesterase Inhibitors; Echothiophate Iodide; Erythrocyt

1972