isoflurophate has been researched along with Alzheimer Disease in 3 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| " AMS measures radioisotopes such as 3H, 14C, 26Al, 36Cl and 41Ca, with zepto- or attomole sensitivity and high precision and throughput, allowing safe human pharmacokinetic studies involving microgram doses, agents having low bioavailability or toxicology studies where administered doses must be kept low (<1 microg kg(-1))." | 2.43 | Neuroscience and accelerator mass spectrometry. ( Buchholz, BA; Hillegonds, DJ; Palmblad, M; Vogel, JS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palmblad, M | 1 |
| Buchholz, BA | 1 |
| Hillegonds, DJ | 1 |
| Vogel, JS | 1 |
| Haroutunian, V | 1 |
| Greig, N | 1 |
| Pei, XF | 1 |
| Utsuki, T | 1 |
| Gluck, R | 1 |
| Acevedo, LD | 1 |
| Davis, KL | 1 |
| Wallace, WC | 1 |
| Fryer, GC | 1 |
1 review available for isoflurophate and Alzheimer Disease
| Article | Year |
|---|---|
Neuroscience and accelerator mass spectrometry.
Topics: Age Factors; Alzheimer Disease; Animals; Blood-Brain Barrier; Brain Chemistry; Carbon Radioisotopes; | 2005 |
2 other studies available for isoflurophate and Alzheimer Disease
| Article | Year |
|---|---|
Pharmacological modulation of Alzheimer's beta-amyloid precursor protein levels in the CSF of rats with forebrain cholinergic system lesions.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Isoflurophate | 1997 |
Dementing disease in a married couple.
Topics: Adult; Alzheimer Disease; Female; Humans; Isoflurophate; Occupational Diseases; Poisoning | 1991 |