isoflurophate has been researched along with Acute Brain Injuries in 7 studies
Isoflurophate: A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We demonstrate that NV354, in combination with atropine and pralidoxime therapy, significantly improved cerebral mitochondrial complex IV-linked respiration and reduced signs of brain injury in a rodent model of acute DFP exposure." | 5.72 | Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning. ( Clayman, CL; Ehinger, JK; Elmér, E; Hansson, MJ; Jang, DH; Janowska, JI; Jose, JS; Karlsson, M; Kilbaugh, TJ; McManus, MJ; Piel, S; Sheldon, M; Starr, J; Ward, JL, 2022) |
| "Seizures were elicited within ∼8 minutes after DFP exposure that progressively developed into persistent SE lasting for hours." | 5.48 | Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. ( Kuruba, R; Reddy, DS; Wu, X, 2018) |
| " We demonstrate that NV354, in combination with atropine and pralidoxime therapy, significantly improved cerebral mitochondrial complex IV-linked respiration and reduced signs of brain injury in a rodent model of acute DFP exposure." | 1.72 | Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning. ( Clayman, CL; Ehinger, JK; Elmér, E; Hansson, MJ; Jang, DH; Janowska, JI; Jose, JS; Karlsson, M; Kilbaugh, TJ; McManus, MJ; Piel, S; Sheldon, M; Starr, J; Ward, JL, 2022) |
| "Seizures were elicited within ∼8 minutes after DFP exposure that progressively developed into persistent SE lasting for hours." | 1.48 | Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. ( Kuruba, R; Reddy, DS; Wu, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Piel, S | 3 |
| Janowska, JI | 3 |
| Ward, JL | 3 |
| McManus, MJ | 3 |
| Jose, JS | 3 |
| Starr, J | 3 |
| Sheldon, M | 3 |
| Clayman, CL | 3 |
| Elmér, E | 3 |
| Hansson, MJ | 3 |
| Jang, DH | 3 |
| Karlsson, M | 3 |
| Ehinger, JK | 3 |
| Kilbaugh, TJ | 3 |
| Rojas, A | 1 |
| Wang, J | 1 |
| Glover, A | 1 |
| Dingledine, R | 1 |
| Enderlin, J | 1 |
| Igert, A | 1 |
| Auvin, S | 1 |
| Nachon, F | 1 |
| Dal Bo, G | 1 |
| Dupuis, N | 1 |
| Reddy, DS | 2 |
| Zaayman, M | 1 |
| Kuruba, R | 2 |
| Wu, X | 2 |
| Hobson, BA | 1 |
| Rowland, DJ | 1 |
| Supasai, S | 1 |
| Harvey, DJ | 1 |
| Lein, PJ | 1 |
| Garbow, JR | 1 |
| Ferchmin, PA | 1 |
| Andino, M | 1 |
| Reyes Salaman, R | 1 |
| Alves, J | 1 |
| Velez-Roman, J | 1 |
| Cuadrado, B | 1 |
| Carrasco, M | 1 |
| Torres-Rivera, W | 1 |
| Segarra, A | 1 |
| Martins, AH | 1 |
| Lee, JE | 1 |
| Eterovic, VA | 1 |
7 other studies available for isoflurophate and Acute Brain Injuries
| Article | Year |
|---|---|
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphat | 2022 |
Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats.
Topics: Acetylcholinesterase; Animals; Brain Injuries; Diazepam; Disease Models, Animal; Electroencephalogra | 2020 |
Characterization of organophosphate-induced brain injuries in a convulsive mouse model of diisopropylfluorophosphate exposure.
Topics: Animals; Brain; Brain Injuries; Cholinesterase Inhibitors; Disease Models, Animal; Electrocorticogra | 2020 |
Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Diazepam; Hippocampus; Isoflurophate; Male; Neurons | 2021 |
A magnetic resonance imaging study of early brain injury in a rat model of acute DFP intoxication.
Topics: Animals; Brain Injuries; Disease Models, Animal; Isoflurophate; Magnetic Resonance Imaging; Male; Ra | 2018 |
Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents.
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Brain Injuries; Cholinesterase Inhibitors; Drug Re | 2018 |
4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration.
Topics: Acetylcholinesterase; Animals; Brain Injuries; CA1 Region, Hippocampal; Cell Death; Cholinesterase I | 2014 |