isoflurane has been researched along with Ventricular Dysfunction, Left in 15 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 5.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| "Adenosine and high-concentration isoflurane are commonly used to induce hyperemia for assessment of coronary flow reserve (CFR) in mice, but high-concentration isoflurane may exacerbate cardiac dysfunction, leading to impaired CFR." | 3.78 | Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload. ( Ge, J; Wu, J; You, J; Zou, Y, 2012) |
| "Isoflurane and halothane produce favorable alterations in the determinants of left ventricular afterload before, but not after, the production of experimental left ventricular dysfunction by sustained, rapid cardiac pacing in chronically instrumented dogs." | 3.69 | The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy. ( Hettrick, DA; Kersten, JR; Lowe, D; Pagel, PS; Warltier, DC, 1997) |
| "Isoflurane treatment was started at 0, 10, 30 (early treatment) or 120 (late treatment) minutes after isoprenaline injection." | 1.46 | Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo. ( Ali, A; Alkhoury, J; Omerovic, E; Oras, J; Redfors, B; Ricksten, SE; Seeman-Lodding, H, 2017) |
| "Pompe's disease is an autosomal recessive and often fatal condition, caused by mutations in the acid alpha-glucosidase gene, leading to lysosomal glycogen storage in heart and skeletal muscle." | 1.31 | Cardiac remodeling and contractile function in acid alpha-glucosidase knockout mice. ( Duncker, DJ; Kamphoven, JH; Reuser, AJ; Stubenitsky, R; Van Der Ploeg, AT; Verdouw, PD, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cuijpers, I | 1 |
| Carai, P | 1 |
| Mendes-Ferreira, P | 1 |
| Simmonds, SJ | 1 |
| Mulder, P | 1 |
| Miranda-Silva, D | 1 |
| De Giorgio, D | 1 |
| Pokreisz, P | 1 |
| Heymans, S | 1 |
| Jones, EAV | 1 |
| Bakermans, AJ | 1 |
| Abdurrachim, D | 1 |
| van Nierop, BJ | 1 |
| Koeman, A | 1 |
| van der Kroon, I | 1 |
| Baartscheer, A | 1 |
| Schumacher, CA | 1 |
| Strijkers, GJ | 1 |
| Houten, SM | 1 |
| Zuurbier, CJ | 1 |
| Nicolay, K | 1 |
| Prompers, JJ | 1 |
| Oras, J | 1 |
| Redfors, B | 1 |
| Ali, A | 1 |
| Alkhoury, J | 1 |
| Seeman-Lodding, H | 1 |
| Omerovic, E | 1 |
| Ricksten, SE | 1 |
| Yildirim, V | 1 |
| Doganci, S | 1 |
| Aydin, A | 1 |
| Bolcal, C | 1 |
| Demirkilic, U | 1 |
| Cosar, A | 1 |
| Couture, P | 1 |
| Denault, AY | 1 |
| Shi, Y | 1 |
| Deschamps, A | 1 |
| Cossette, M | 1 |
| Pellerin, M | 1 |
| Tardif, JC | 1 |
| You, J | 1 |
| Wu, J | 1 |
| Ge, J | 1 |
| Zou, Y | 1 |
| Seehase, M | 1 |
| Houthuizen, P | 1 |
| Jellema, RK | 1 |
| Collins, JJ | 1 |
| Bekers, O | 1 |
| Breuer, J | 1 |
| Kramer, BW | 1 |
| Kehl, F | 1 |
| Ladisa, JF | 1 |
| Hettrick, DA | 3 |
| Kersten, JR | 4 |
| Warltier, DC | 5 |
| Pagel, PS | 5 |
| Chiari, PC | 1 |
| Bienengraeber, MW | 1 |
| Krolikowski, JG | 1 |
| Neuhäuser, C | 1 |
| Müller, M | 1 |
| Welters, I | 1 |
| Scholz, S | 1 |
| Kwapisz, MM | 1 |
| Hartley, CJ | 1 |
| Reddy, AK | 1 |
| Madala, S | 1 |
| Michael, LH | 1 |
| Entman, ML | 1 |
| Taffet, GE | 1 |
| Lowe, D | 2 |
| Jamali, IN | 1 |
| Tessmer, JP | 1 |
| Kamphoven, JH | 1 |
| Stubenitsky, R | 1 |
| Reuser, AJ | 1 |
| Van Der Ploeg, AT | 1 |
| Verdouw, PD | 1 |
| Duncker, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Remifentanil on Diastolic and Systolic Function in Patients With Diastolic Dysfunction[NCT04117009] | Phase 4 | 30 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for isoflurane and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Cardioprotective effects of sevoflurane, isoflurane, and propofol in coronary surgery patients: a randomized controlled study.
Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypas | 2009 |
Effect of isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; Cardiovascular Phy | 2006 |
13 other studies available for isoflurane and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
The effect of different anaesthetics on echocardiographic evaluation of diastolic dysfunction in a heart failure with preserved ejection fraction model.
Topics: Anesthetics; Animals; Diastole; Echocardiography; Heart Failure; Heart Rate; Isoflurane; Ketamine; M | 2020 |
In vivo mouse myocardial (31)P MRS using three-dimensional image-selected in vivo spectroscopy (3D ISIS): technical considerations and biochemical validations.
Topics: Adenosine Triphosphate; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Aorta; Energy Meta | 2015 |
Early treatment with isoflurane attenuates left ventricular dysfunction and improves survival in experimental Takotsubo.
Topics: Adrenergic beta-Agonists; Anesthetics, Inhalation; Animals; Cardiac Output; Echocardiography; Isoflu | 2017 |
Effects of anesthetic induction in patients with diastolic dysfunction.
Topics: Aged; Anesthesia, General; Anesthetics, General; Blood Flow Velocity; Blood Pressure; Coronary Arter | 2009 |
Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload.
Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Echocardiography, Doppler; Feasibi | 2012 |
Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Animals, Newborn; Asphyxia Neonatorum; B | 2013 |
Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships.
Topics: Anesthetics, Inhalation; Animals; Atrial Function, Left; Blood Pressure; Cardiac Pacing, Artificial; | 2003 |
Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits.
Topics: Anesthetics, Inhalation; Animals; Blotting, Western; Dose-Response Relationship, Drug; Enzyme Activa | 2005 |
Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy.
Topics: Anesthetics; Animals; Aortic Valve; Blood Flow Velocity; Cardiomegaly; Coronary Vessels; Hyperemia; | 2008 |
Mechanical consequences of calcium channel modulation during volatile anesthetic-induced left ventricular systolic and diastolic dysfunction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Isoflurane, but not halothane, improves indices of diastolic performance in dogs with rapid ventricular, pacing-induced cardiomyopathy.
Topics: Anesthetics, Inhalation; Animals; Cardiac Pacing, Artificial; Diastole; Dogs; Halothane; Isoflurane; | 1996 |
The effects of isoflurane and halothane on left ventricular afterload in dogs with dilated cardiomyopathy.
Topics: Anesthetics, Inhalation; Animals; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Disease Model | 1997 |
Cardiac remodeling and contractile function in acid alpha-glucosidase knockout mice.
Topics: alpha-Glucosidases; Anesthetics, Inhalation; Animals; Cardiomyopathy, Hypertrophic; Dobutamine; Gluc | 2001 |