Page last updated: 2024-10-29

isoflurane and Vasospasm, Intracranial

isoflurane has been researched along with Vasospasm, Intracranial in 7 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).

Research Excerpts

ExcerptRelevanceReference
"To evaluate whether isoflurane induced hypotension increases the incidence of cerebral vasospasm in intracranial aneurysm surgery."9.11[The effect of isoflurane induced hypotension on intraoperative cerebral vasospasm in intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)."9.11[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS)."8.02Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Zipfel, GJ, 2021)
" Our data show that isoflurane dosing typically used for general anesthesia (1%) or sedation (0."5.62Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage. ( Athiraman, U; Jayaraman, K; Liu, M; Mehla, J; Yuan, J; Zipfel, GJ, 2021)
"To evaluate whether isoflurane induced hypotension increases the incidence of cerebral vasospasm in intracranial aneurysm surgery."5.11[The effect of isoflurane induced hypotension on intraoperative cerebral vasospasm in intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"Thirty consecutive patients under-going intracranial aneurysmal surgery were prospectively randomized into two groups: Isoflurane (group A, n = 15) and nimodipine (group B, n = 15)."5.11[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery]. ( Han, RQ; Li, SR; Liu, W; Wang, BG; Wang, EZ; Wang, S; Zhao, JZ, 2004)
"We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS)."4.02Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage. ( Athiraman, U; Giri, T; Jayaraman, K; Liu, M; Zipfel, GJ, 2021)
" Our data show that isoflurane dosing typically used for general anesthesia (1%) or sedation (0."1.62Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage. ( Athiraman, U; Jayaraman, K; Liu, M; Mehla, J; Yuan, J; Zipfel, GJ, 2021)
"Cerebral vasospasm is the most important cause of morbidity after an aneurysm clipping in the early postoperative period."1.48The effect of anesthetic agents on cerebral vasospasms after subarachnoid hemorrhage: A retrospective study. ( Baik, HJ; Chae, JS; Kim, DY; Lee, JW; Seo, EK; Woo, JH; Yang, NR, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Liu, M3
Jayaraman, K3
Norris, AJ1
Hussein, A1
Nelson, JW1
Mehla, J2
Diwan, D1
Vellimana, A1
Abu-Amer, Y1
Zipfel, GJ3
Athiraman, U3
Yuan, J1
Giri, T1
Lee, JW1
Woo, JH1
Baik, HJ1
Kim, DY1
Chae, JS1
Yang, NR1
Seo, EK1
Han, RQ2
Li, SR2
Wang, BG2
Wang, EZ2
Liu, W2
Wang, S2
Zhao, JZ2
Münte, S1
Münte, TF1
Kuche, H1
Osthaus, A1
Herzog, T1
Heine, J1
Leuwer, M1
Piepenbrock, S1

Trials

3 trials available for isoflurane and Vasospasm, Intracranial

ArticleYear
[The effect of isoflurane induced hypotension on intraoperative cerebral vasospasm in intracranial aneurysm surgery].
    Zhonghua yi xue za zhi, 2004, Feb-17, Volume: 84, Issue:4

    Topics: Adult; Aged; Anesthetics, Inhalation; Blood Pressure; Female; Follow-Up Studies; Humans; Hypotension

2004
[The effect of intraoperative continuous nimodipine infusion on cerebral vasospasm during intracranial aneurysm surgery].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Dec-22, Volume: 42, Issue:24

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Huma

2004
General anesthesia for interventional neuroradiology: propofol versus isoflurane.
    Journal of clinical anesthesia, 2001, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; An

2001

Other Studies

4 other studies available for isoflurane and Vasospasm, Intracranial

ArticleYear
Isoflurane Conditioning-Induced Delayed Cerebral Ischemia Protection in Subarachnoid Hemorrhage-Role of Inducible Nitric Oxide Synthase.
    Journal of the American Heart Association, 2023, 07-18, Volume: 12, Issue:14

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Isoflurane; Male; Mice; Mice, Inbred C57BL; Mice, Knoc

2023
Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage.
    Brain research, 2021, 01-01, Volume: 1750

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Isoflurane; Male; Mice; Mice,

2021
Role of SIRT1 in Isoflurane Conditioning-Induced Neurovascular Protection against Delayed Cerebral Ischemia Secondary to Subarachnoid Hemorrhage.
    International journal of molecular sciences, 2021, Apr-20, Volume: 22, Issue:8

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Fluorescent Antibody Technique; Gene Expression; Is

2021
The effect of anesthetic agents on cerebral vasospasms after subarachnoid hemorrhage: A retrospective study.
    Medicine, 2018, Volume: 97, Issue:31

    Topics: Adult; Anesthetics; Desflurane; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Intraoper

2018