Page last updated: 2024-10-29

isoflurane and Torsade de Pointes

isoflurane has been researched along with Torsade de Pointes in 5 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Research Excerpts

ExcerptRelevanceReference
"We simultaneously assessed electropharmacological effects of anti-atrial fibrillatory drug vernakalant and its potential risk toward torsade de pointes."8.31Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anesthetized dogs and isolated rat aortic preparations. ( Goto, A; Izumi-Nakaseko, H; Kambayashi, R; Shinozaki, M; Sugiyama, A; Takei, Y, 2023)
" In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane."7.71Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001)
"We simultaneously assessed electropharmacological effects of anti-atrial fibrillatory drug vernakalant and its potential risk toward torsade de pointes."4.31Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anesthetized dogs and isolated rat aortic preparations. ( Goto, A; Izumi-Nakaseko, H; Kambayashi, R; Shinozaki, M; Sugiyama, A; Takei, Y, 2023)
"Thiopental anesthesia causes arrhythmias sec, whereas anesthesia in general predisposes for drug-induced TdP in the CAVB dog."3.76Anesthesia and arrhythmogenesis in the chronic atrioventricular block dog model. ( Beekman, J; Dunnink, A; Montagne, D; Oosterhoff, P; Sharif, S; van der Heyden, MA; van der Nagel, R; Vos, MA; Winckels, S, 2010)
" In order to study the effects of anesthetic agents on the inducibility of TdP, arrhythmias were induced by programmed electrical stimulation (PES) before and after cumulative intravenous administration of quinidine under anesthesia with sodium pentobarbital, halothane, or isoflurane."3.71Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. ( Imai, R; Tamura, T; Yamamoto, K; Yamamoto, M, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Goto, A1
Kambayashi, R1
Izumi-Nakaseko, H1
Shinozaki, M1
Takei, Y1
Sugiyama, A1
Limprasutr, V1
Saengklub, N1
Meedech, P1
Kijtawornrat, A1
Hamlin, RL1
Dunnink, A1
Sharif, S1
Oosterhoff, P1
Winckels, S1
Montagne, D1
Beekman, J1
van der Nagel, R1
van der Heyden, MA1
Vos, MA1
Yamamoto, K1
Tamura, T1
Imai, R1
Yamamoto, M1
Zhou, S1
Cao, JM1
Ohara, T1
KenKnight, BH1
Chen, LS1
Karagueuzian, HS1
Chen, PS1

Other Studies

5 other studies available for isoflurane and Torsade de Pointes

ArticleYear
Characterization of electropharmacological profile of an anti-atrial fibrillatory drug vernakalant along with potential risk toward torsade de pointes: Translational studies using isoflurane-anesthetized dogs and isolated rat aortic preparations.
    Journal of pharmacological sciences, 2023, Volume: 152, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Dogs; Isoflurane; Rats; Torsades de Pointes

2023
Characteristics of electromechanical window in anesthetized rabbit models of short QT and long QT syndromes.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:5

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzopyrans; Biomarkers; Biomarkers, Pharmacological; Cro

2017
Anesthesia and arrhythmogenesis in the chronic atrioventricular block dog model.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:6

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Atrioventricular Block; Dogs; Female; Halothane; Heart Bl

2010
Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: Acute Disease; Anesthesia; Anesthetics, Inhalation; Animals; Astemizole; Atrioventricular Node; Cath

2001
Torsade de pointes and sudden death induced by thiopental and isoflurane anesthesia in dogs with cardiac electrical remodeling.
    Journal of cardiovascular pharmacology and therapeutics, 2002, Volume: 7, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Death, Sudden, Cardiac; Disease Models,

2002