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isoflurane and Spinal Cord Injuries

isoflurane has been researched along with Spinal Cord Injuries in 22 studies

Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Malignant hyperthermia was suspected and the treatment was started, but he developed cardiopulmonary arrest and died an hour and a half after the first cardiac arrest."1.72Spinal cord injury-related thermoregulatory impairment masks a fatal malignant hyperthermia crisis: a case report. ( Alves, JFF; Amaral, JLG; Andrade, PV; Lutke, C; Santos, JM; Silva, HCA; Souza, LS; Vainzof, M, 2022)
"Neurogenic pulmonary edema (NPE) is an acute life-threatening complication following an injury of the spinal cord or brain, which is associated with sympathetic hyperactivity."1.35The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions. ( Hejcl, A; Kunes, J; Sedy, J; Syková, E; Zicha, J, 2009)
"The pulmonary edema was elicited by an epidural thoracic balloon compression spinal cord lesion, performed under a low concentration of isoflurane (1."1.34A new model of severe neurogenic pulmonary edema in spinal cord injured rat. ( Hejcl, A; Jendelová, P; Likavcanová, K; Sedý, J; Syková, E; Urdzíková, L, 2007)
"Spinal cord ischemia was induced by an infrarenal aorta clamping for 20 min."1.33Isoflurane produces delayed preconditioning against spinal cord ischemic injury via release of free radicals in rabbits. ( Cao, L; Qiu, P; Sang, H; Wang, R; Xiong, L; Yan, G, 2006)
" Dose-response curves describing the relationship between the duration of balloon inflation and the percentage of animals with a persistent neurologic deficit were constructed and compared for differences by use of a group t test."1.28The effect of fentanyl anesthesia and intrathecal naloxone on neurologic outcome following spinal cord injury in the rat. ( Brauer, FS; Cole, DJ; Drummond, JC; Hertzog, RE; Shapiro, HM, 1989)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's4 (18.18)18.2507
2000's8 (36.36)29.6817
2010's6 (27.27)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Andrade, PV1
Souza, LS1
Santos, JM1
Alves, JFF1
Lutke, C1
Amaral, JLG1
Vainzof, M1
Silva, HCA1
Davis, JA1
Bopp, AC1
Henwood, MK1
Bean, P1
Grau, JW1
Ishikawa, T1
Suzuki, H1
Ishikawa, K1
Yasuda, S1
Matsui, T1
Yamamoto, M1
Kakeda, T1
Yamamoto, S1
Owada, Y1
Yaksh, TL1
Allard, J1
Edmunds, NJ1
Sedy, J3
Zicha, J2
Kunes, J2
Hejcl, A3
Syková, E3
Agrawal, G1
Iyer, S2
All, AH2
Maybhate, A1
Presacco, A1
Nout, YS1
Beattie, MS1
Bresnahan, JC1
Roustan, A1
Perrin, J1
Berthelot-Ricou, A1
Lopez, E1
Botta, A1
Courbiere, B1
Carbone, L1
Carbone, ET1
Yi, EM1
Bauer, DB1
Lindstrom, KA1
Parker, JM1
Austin, JA1
Seo, Y1
Gandhi, AD1
Wilkerson, JD1
Golledge, HD1
Jinks, SL1
Dominguez, CL1
Antognini, JF1
Ewen, A1
Cox, RG1
Davies, SA1
Luntley, JB1
Rubin, Y1
Fick, GH1
Bart, BB1
Sang, H1
Cao, L1
Qiu, P1
Xiong, L1
Wang, R1
Yan, G1
Urdzíková, L2
Likavcanová, K2
Jendelová, P2
Burian, M1
Grissom, TE1
Mitzel, HC1
Bunegin, L1
Albin, MS1
Kaneko, K1
Kawai, S1
Fuchigami, Y1
Shiraishi, G1
Ito, T1
Leis, AA1
Zhou, HH1
Mehta, M1
Harkey, HL1
Paske, WC1
Perlik, SJ1
VanEgeren, R1
Fisher, MA1
Cole, DJ1
Drummond, JC1
Shapiro, HM1
Hertzog, RE1
Brauer, FS1
Benthuysen, JL1

Reviews

1 review available for isoflurane and Spinal Cord Injuries

ArticleYear
Spinal cord ischemia/injury.
    Current pharmaceutical design, 2014, Volume: 20, Issue:36

    Topics: Analgesics; Anesthetics; Anesthetics, Inhalation; Animals; Humans; Isoflurane; Neuroprotective Agent

2014

Trials

2 trials available for isoflurane and Spinal Cord Injuries

ArticleYear
The ankle clonus test is not a clinically useful measure of spinal cord integrity in children.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:5

    Topics: Adolescent; Ankle Joint; Body Temperature; Child; Child, Preschool; Female; Humans; Isoflurane; Male

2005
Naloxone therapy in spinal trauma: anesthetic effects.
    Anesthesiology, 1987, Volume: 66, Issue:2

    Topics: Adult; Anesthesia, General; Clinical Trials as Topic; Drug Evaluation; Humans; Hyperventilation; Int

1987

Other Studies

19 other studies available for isoflurane and Spinal Cord Injuries

ArticleYear
Spinal cord injury-related thermoregulatory impairment masks a fatal malignant hyperthermia crisis: a case report.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022, Volume: 69, Issue:3

    Topics: Adult; Anesthetics; Humans; Isoflurane; Male; Malignant Hyperthermia; Ryanodine Receptor Calcium Rel

2022
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
    Journal of neurotrauma, 2023, Volume: 40, Issue:23-24

    Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba

2023
Reflex penile erection in anesthetized mice: an exploratory study.
    Neuroscience, 2008, Jul-31, Volume: 155, Issue:1

    Topics: alpha-MSH; Anesthesia; Animals; Area Under Curve; Blood Pressure; Dose-Response Relationship, Radiat

2008
The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Atropine; Baroreflex; Blood Pressure; Bradycardia; Disease Models,

2009
A comparative study of recording procedures for motor evoked potential signals.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2009, Volume: 2009

    Topics: Analysis of Variance; Anesthesia; Anesthetics; Animals; Electric Stimulation; Electrodes, Implanted;

2009
Multi-limb acquisition of motor evoked potentials and its application in spinal cord injury.
    Journal of neuroscience methods, 2010, Nov-30, Volume: 193, Issue:2

    Topics: Analgesics; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Mo

2010
Severity of locomotor and cardiovascular derangements after experimental high-thoracic spinal cord injury is anesthesia dependent in rats.
    Journal of neurotrauma, 2012, Mar-20, Volume: 29, Issue:5

    Topics: Anesthetics; Animals; Blood Pressure; Cardiovascular System; Disease Models, Animal; Female; Heart R

2012
Evaluating methods of mouse euthanasia on the oocyte quality: cervical dislocation versus isoflurane inhalation.
    Laboratory animals, 2012, Volume: 46, Issue:2

    Topics: Administration, Inhalation; Anesthetics, Inhalation; Animal Use Alternatives; Animal Welfare; Animal

2012
Assessing cervical dislocation as a humane euthanasia method in mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2012, Volume: 51, Issue:3

    Topics: Anesthetics, Inhalation; Animal Welfare; Animals; Cervical Vertebrae; Euthanasia, Animal; Female; Is

2012
Response to Roustan et al. 'Evaluating methods of mouse euthanasia on the oocyte quality: cervical dislocation versus isoflurane inhalation': animal welfare concerns regarding the aversiveness of isoflurane and its inability to cause rapid death.
    Laboratory animals, 2012, Volume: 46, Issue:4

    Topics: Anesthetics, Inhalation; Animal Use Alternatives; Animals; Euthanasia, Animal; Female; Isoflurane; M

2012
Drastic decrease in isoflurane minimum alveolar concentration and limb movement forces after thoracic spinal cooling and chronic spinal transection in rats.
    Anesthesiology, 2005, Volume: 102, Issue:3

    Topics: Anesthetics, Inhalation; Animals; Extremities; Female; Isoflurane; Movement; Muscle Spasticity; Neur

2005
Isoflurane produces delayed preconditioning against spinal cord ischemic injury via release of free radicals in rabbits.
    Anesthesiology, 2006, Volume: 105, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Free Radical Scavengers; Free Radicals; Ischemic Preconditioning;

2006
A new model of severe neurogenic pulmonary edema in spinal cord injured rat.
    Neuroscience letters, 2007, Aug-16, Volume: 423, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Isoflura

2007
Low concentration of isoflurane promotes the development of neurogenic pulmonary edema in spinal cord injured rats.
    Journal of neurotrauma, 2007, Volume: 24, Issue:9

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Isof

2007
The effect of anesthetics on neurologic outcome during the recovery period of spinal cord injury in rats.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:1

    Topics: Anesthetics; Animals; Central Nervous System; Female; Fentanyl; Isoflurane; Ketamine; Nitrous Oxide;

1994
Effect of stimulus intensity and voluntary contraction on corticospinal potentials following transcranial magnetic stimulation.
    Journal of the neurological sciences, 1996, Volume: 139, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Brachial Plexus; Evoked Potentials; Female; Hum

1996
Behavior of the H-reflex in humans following mechanical perturbation or injury to rostral spinal cord.
    Muscle & nerve, 1996, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Anesthesia, General; Female; H-Reflex; Humans; Intraoperative Period; Isoflurane;

1996
Somatosensory evoked potential surgical monitoring. Observations during combined isoflurane-nitrous oxide anesthesia.
    Spine, 1992, Volume: 17, Issue:3

    Topics: Adolescent; Anesthesia, Inhalation; Cervical Vertebrae; Evoked Potentials, Somatosensory; Female; Hu

1992
The effect of fentanyl anesthesia and intrathecal naloxone on neurologic outcome following spinal cord injury in the rat.
    Anesthesiology, 1989, Volume: 71, Issue:3

    Topics: Anesthesia Recovery Period; Animals; Catheterization; Dose-Response Relationship, Drug; Drug Interac

1989