isoflurane has been researched along with Psychomotor Agitation in 22 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of alfentanil in suppressing coughing and agitation during emergence from isoflurane anesthesia." | 9.08 | Alfentanil suppresses coughing and agitation during emergence from isoflurane anesthesia. ( Fredman, B; Mendel, P; White, PF, 1995) |
| "To evaluate the effectiveness of alfentanil in suppressing coughing and agitation during emergence from isoflurane anesthesia." | 5.08 | Alfentanil suppresses coughing and agitation during emergence from isoflurane anesthesia. ( Fredman, B; Mendel, P; White, PF, 1995) |
| "Remifentanil was infused at 0." | 2.79 | Dexmedetomidine does not reduce emergence agitation in adults following orthognathic surgery. ( Ham, SY; Kim, JE; Park, C; Shim, YH; Shin, MJ, 2014) |
| "Tramadol was used for postoperative analgesia." | 2.71 | Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2004) |
| "Desflurane has been used in paediatric patients for several surgical indications." | 1.46 | Clinical experience with desflurane for paediatric anaesthesia outside the operating room. ( Alonso, M; Builes, L; Fernández, E; Morán, P; Ortega, A; Reinoso-Barbero, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oofuvong, M | 1 |
| Siripruekpong, S | 1 |
| Naklongdee, J | 1 |
| Hnookong, R | 1 |
| Lakateb, C | 1 |
| Liu, GY | 1 |
| Chen, ZQ | 1 |
| Zhang, ZW | 1 |
| Ham, SY | 1 |
| Kim, JE | 2 |
| Park, C | 1 |
| Shin, MJ | 1 |
| Shim, YH | 1 |
| Choi, GJ | 1 |
| Baek, CW | 1 |
| Kang, H | 1 |
| Park, YH | 2 |
| Yang, SY | 1 |
| Shin, HY | 1 |
| Jung, YH | 1 |
| Woo, YC | 1 |
| Lee, UL | 1 |
| Kim, HS | 1 |
| Byon, HJ | 1 |
| Lee, JH | 1 |
| Kim, JT | 1 |
| Jiang, S | 1 |
| Liu, J | 1 |
| Li, M | 1 |
| Ji, W | 1 |
| Liang, J | 1 |
| Alonso, M | 1 |
| Builes, L | 1 |
| Morán, P | 1 |
| Ortega, A | 1 |
| Fernández, E | 1 |
| Reinoso-Barbero, F | 1 |
| Petrenko, AB | 1 |
| Kohno, T | 1 |
| Wu, J | 1 |
| Sakimura, K | 1 |
| Baba, H | 1 |
| Tabrizi, R | 1 |
| Eftekharian, HR | 1 |
| Langner, NJ | 1 |
| Ozkan, BT | 1 |
| Cohen, IT | 2 |
| Drewsen, S | 1 |
| Hannallah, RS | 2 |
| Muñoz, HR | 1 |
| Ibacache, ME | 1 |
| Przybylo, HJ | 1 |
| Martini, DR | 1 |
| Mazurek, AJ | 1 |
| Bracey, E | 1 |
| Johnsen, L | 1 |
| Coté, CJ | 1 |
| Stewart, PC | 1 |
| Cunnington, P | 1 |
| Martin, R | 1 |
| Kararmaz, A | 1 |
| Kaya, S | 1 |
| Turhanoglu, S | 1 |
| Ozyilmaz, MA | 1 |
| Demirbilek, S | 1 |
| Togal, T | 1 |
| Cicek, M | 1 |
| Aslan, U | 1 |
| Sizanli, E | 1 |
| Ersoy, MO | 1 |
| Mayer, J | 1 |
| Boldt, J | 1 |
| Röhm, KD | 1 |
| Scheuermann, K | 1 |
| Suttner, SW | 1 |
| Malviya, S | 1 |
| Voepel-Lewis, T | 1 |
| Ramamurthi, RJ | 1 |
| Burke, C | 1 |
| Tait, AR | 1 |
| Bortone, L | 1 |
| Ingelmo, P | 1 |
| Grossi, S | 1 |
| Grattagliano, C | 1 |
| Bricchi, C | 1 |
| Barantani, D | 1 |
| Sani, E | 1 |
| Mergoni, M | 1 |
| Mendel, P | 1 |
| Fredman, B | 1 |
| White, PF | 1 |
| McAuliffe, GL | 1 |
| Sanders, DJ | 1 |
| Mills, PJ | 1 |
| Finkel, JC | 1 |
| Hummer, KA | 1 |
| Patel, KM | 1 |
| Breheny, FX | 1 |
| Kendall, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Emergence Delirium in Children: a Randomized Clinical Trial of Different Doses of Sevoflurane During Induction of Anesthesia[NCT02707016] | 80 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting | |||
| Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954] | 54 participants (Actual) | Interventional | 2018-05-31 | Completed | |||
| Effects of Dexmedetomidine on Cough Response and Postoperative Recovery Quality in Patients Undergoing Thyroid Surgery With General anesthesia---a Randomized Control Double-Blind Clinical Trial[NCT02613806] | Phase 4 | 118 participants (Anticipated) | Interventional | 2015-12-31 | Not yet recruiting | ||
| The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy[NCT04712162] | 60 participants (Actual) | Interventional | 2019-11-19 | Completed | |||
| Pharmacokinetic-pharmacodynamic Analysis for Dosing Strategy and Evaluation of Safety and Efficacy of Dexmedetomidine in Children[NCT04027829] | Phase 2 | 13 participants (Actual) | Interventional | 2019-08-14 | Completed | ||
| Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant[NCT02819089] | 100 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | |||
| Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD)[NCT02422290] | Phase 1/Phase 2 | 5 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| Comparing the Efficacy Between Desflurane and Sevoflurane in Miantainance of Spontaneous General Anaesthesia Using Ambu Aura Gain in Paediatrics Patients[NCT04771962] | Phase 1/Phase 2 | 80 participants (Actual) | Interventional | 2020-01-01 | Completed | ||
| Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.[NCT02181543] | Phase 3 | 30 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| Effect of Two Plasma Concentrations of Remifentanil Through Target Controlled Anesthesia on Frequency and Intensity of Coughing During Extubation: Randomized Controlled Clinical Trial[NCT02711904] | Phase 4 | 110 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric[NCT02463929] | Phase 4 | 50 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The CY-BOCS is a semi-structured measure of OCD severity with excellent inter-rater reliability, internal consistency, and test-retest reliability. It is validated in those starting at age 7 and used in studies up to age 20. The CYBOCS differs from the adult YBOCS only in its use of simpler language. The CY-BOCS consists of 10 items which are summed up to derive the total CY-BOCS score. The total score ranges from 0-40 with higher scores indicating greater severity of OCD symptoms. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| CY-BOCS Baseline | CY-BOCS Day 14 | |
| Ketamine Treatment Group | 29.00 | 26.20 |
The CGI-S is a clinician rated 7-point rating scale for the severity of a participant's illness relative to the clinician's experience of working with this particular population. The score ranges from 1-7 with higher scores indicating greater illness severity. (NCT02422290)
Timeframe: Screening, Baseline, Day 7, Day 17, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| CGI-S Baseline | CGI-S Day 14 | |
| Ketamine Treatment Group | 5.80 | 5.00 |
"The OCD-VAS is a one-item unipolar scale to assess OCD symptoms over a rapid time frame (No obsessions to Constant obsessions). The scale ranges from 0-10 with higher scores indicating higher presence of obsessions." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| OCD-VAS Baseline | OCD-VAS Day 14 | |
| Ketamine Treatment Group | 5.00 | 5.00 |
"The Y-BOCCS is self-report scale which assesses OCD symptoms on a 5-point likert scale (None to Extreme). It consists of 10 items which are summed up to derive the total Y-BOCCS score. The total score ranges from 0-40 with higher scores indicating higher prevalence of OCD symptoms." (NCT02422290)
Timeframe: Screening, Baseline, Day 1-14, 3-Month; Baseline and Day 14 pre-specified to be reported
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Y-BOCCS Baseline | Y-BOCCS Day 14 | |
| Ketamine Treatment Group | 18.25 | 16.50 |
1 review available for isoflurane and Psychomotor Agitation
| Article | Year |
|---|---|
The efficacy of propofol on emergence agitation--a meta-analysis of randomized controlled trials.
Topics: Desflurane; Humans; Isoflurane; Length of Stay; Methyl Ethers; Propofol; Psychomotor Agitation; Rand | 2015 |
15 trials available for isoflurane and Psychomotor Agitation
| Article | Year |
|---|---|
Comparison the incidence of emergence agitation between sevoflurane and desflurane after pediatric ambulatory urologic surgery.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Female; Hu | 2013 |
Comparative study of emergence agitation between isoflurane and propofol anesthesia in adults after closed reduction of distal radius fracture.
Topics: Adult; Aged; Anesthesia; Demography; Female; Humans; Isoflurane; Male; Middle Aged; Perioperative Ca | 2014 |
Dexmedetomidine does not reduce emergence agitation in adults following orthognathic surgery.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Cough; Delayed Emergence from Anesthesia; De | 2014 |
Emergence agitation after orthognathic surgery: a randomised controlled comparison between sevoflurane and desflurane.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Desflurane; Double-Blind Met | 2015 |
Appropriate dose of dexmedetomidine for the prevention of emergence agitation after desflurane anesthesia for tonsillectomy or adenoidectomy in children: up and down sequential allocation.
Topics: Adenoidectomy; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Dexmedetomidine; Dose-R | 2015 |
Appropriate dose of dexmedetomidine for the prevention of emergence agitation after desflurane anesthesia for tonsillectomy or adenoidectomy in children: up and down sequential allocation.
Topics: Adenoidectomy; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Dexmedetomidine; Dose-R | 2015 |
Appropriate dose of dexmedetomidine for the prevention of emergence agitation after desflurane anesthesia for tonsillectomy or adenoidectomy in children: up and down sequential allocation.
Topics: Adenoidectomy; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Dexmedetomidine; Dose-R | 2015 |
Appropriate dose of dexmedetomidine for the prevention of emergence agitation after desflurane anesthesia for tonsillectomy or adenoidectomy in children: up and down sequential allocation.
Topics: Adenoidectomy; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Dexmedetomidine; Dose-R | 2015 |
Propofol or midazolam do not reduce the incidence of emergence agitation associated with desflurane anaesthesia in children undergoing adenotonsillectomy.
Topics: Adenoidectomy; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Desflur | 2002 |
Assessing behaviour in children emerging from anaesthesia: can we apply psychiatric diagnostic techniques?
Topics: Age Factors; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, | 2003 |
Oral ketamine premedication can prevent emergence agitation in children after desflurane anaesthesia.
Topics: Adenoidectomy; Administration, Oral; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, In | 2004 |
Effects of fentanyl on the incidence of emergence agitation in children receiving desflurane or sevoflurane anaesthesia.
Topics: Adenoidectomy; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics | 2004 |
Desflurane anesthesia after sevoflurane inhaled induction reduces severity of emergence agitation in children undergoing minor ear-nose-throat surgery compared with sevoflurane induction and maintenance.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; D | 2006 |
Clonidine for the prevention of emergence agitation in young children: efficacy and recovery profile.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; Cl | 2006 |
Emergence agitation in preschool children: double-blind, randomized, controlled trial comparing sevoflurane and isoflurane anesthesia.
Topics: Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Inhalation; Child; Child, Preschool; | 2006 |
Alfentanil suppresses coughing and agitation during emergence from isoflurane anesthesia.
Topics: Adult; Alfentanil; Anesthesia; Blood Pressure; Cough; Double-Blind Method; Female; Heart Rate; Human | 1995 |
Effect of humidification on inhalation induction with isoflurane in children.
Topics: Anesthesia, Inhalation; Child; Child, Preschool; Cough; Double-Blind Method; Humans; Humidity; Hypox | 1994 |
The effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anesthesia in children.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Child; Child, Preschool; Desflurane; Female; Fentanyl; | 2002 |
6 other studies available for isoflurane and Psychomotor Agitation
| Article | Year |
|---|---|
Clinical experience with desflurane for paediatric anaesthesia outside the operating room.
Topics: Adolescent; Airway Management; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Presch | 2017 |
Spontaneous hyperactivity in mutant mice lacking the NMDA receptor GluRepsilon1 subunit is aggravated during exposure to 0.1 MAC sevoflurane and is preserved after emergence from sevoflurane anaesthesia.
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation | 2008 |
Comparison of the effect of 2 hypotensive anesthetic techniques on early recovery complications after orthognathic surgery.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi-Square Distributi | 2012 |
Agitation after desflurane and Dixon and Massey up-and-down method.
Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Desflurane; Fentanyl; | 2003 |
Comment on Cohen et al.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Prescho | 2003 |
Use of isoflurane for sedation in intensive care.
Topics: Acute Kidney Injury; Cognition Disorders; Fenthion; Humans; Hypnotics and Sedatives; Isoflurane; Leg | 1992 |