isoflurane has been researched along with Pheochromocytoma in 20 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane was selected as the main agent for induction and maintenance of anesthesia in two patients scheduled for resection of pheochromocytoma." | 7.67 | Isoflurane anesthesia for resection of pheochromocytoma. A report of two cases. ( Moulaert, P; Rolly, G; Thomas, B, 1984) |
| "Isoflurane, a commonly used inhaled anesthetic, induces apoptosis in rat pheochromocytoma cells (PC12) in a concentration-and time-dependent manner with unknown mechanism." | 3.74 | Effect of inhalational anesthetics on cytotoxicity and intracellular calcium differently in rat pheochromocytoma cells (PC12). ( Li, K; Wang, Q; Yao, S, 2008) |
| "Halothane and isoflurane enhanced amyloid beta oligomerization rates and pheochromocytoma cytotoxicity in vitro through a preference for binding small oligomeric species." | 3.72 | Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. ( Carnini, A; Eckenhoff, MF; Eckenhoff, RG; Johansson, JS; Kang, B; Keller, JM; Pidikiti, R; Wei, H; Wei, W, 2004) |
| "Isoflurane was selected as the main agent for induction and maintenance of anesthesia in two patients scheduled for resection of pheochromocytoma." | 3.67 | Isoflurane anesthesia for resection of pheochromocytoma. A report of two cases. ( Moulaert, P; Rolly, G; Thomas, B, 1984) |
| "In the rat pheochromocytoma cell line PC 12, the effects of four volatile anesthetics (halothane, isoflurane, enflurane, methoxyflurane) on the K+-evoked intracellular calcium [( Ca2+]i) rise were investigated using the Ca2+-sensitive fluorescence dye fura-2." | 3.67 | Volatile anesthetics depress the depolarization-induced cytoplasmic calcium rise in PC 12 cells. ( Eckhardt-Wallasch, H; Koschel, K; Kress, HG; Tas, PW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dortzbach, K | 1 |
| Gainsburg, DM | 1 |
| Frost, EA | 1 |
| Eckenhoff, RG | 2 |
| Johansson, JS | 1 |
| Wei, H | 2 |
| Carnini, A | 1 |
| Kang, B | 1 |
| Wei, W | 1 |
| Pidikiti, R | 1 |
| Keller, JM | 1 |
| Eckenhoff, MF | 1 |
| Ng, JM | 1 |
| Bakan, M | 1 |
| Kaya, G | 1 |
| Cakmakkaya, S | 1 |
| Tufanogullari, B | 1 |
| Liang, G | 1 |
| Yang, H | 1 |
| Wang, Q | 2 |
| Hawkins, B | 1 |
| Madesh, M | 1 |
| Wang, S | 1 |
| Li, K | 1 |
| Yao, S | 1 |
| Thomas, B | 1 |
| Moulaert, P | 1 |
| Rolly, G | 1 |
| Fay, ML | 1 |
| Holzman, RS | 1 |
| Michaels, IA | 2 |
| Suzukawa, M | 2 |
| Kitahata, LM | 2 |
| Kopriva, CJ | 2 |
| Ruzbarsky, J | 1 |
| Harrison, J | 1 |
| Sargent, R | 1 |
| Eggers, GW | 1 |
| Munro, J | 1 |
| Hurlbert, BJ | 1 |
| Hill, GE | 1 |
| Lippmann, M | 1 |
| Ford, M | 1 |
| Lee, C | 1 |
| Ginsburg, R | 1 |
| Foran, W | 1 |
| Raum, W | 1 |
| Klein, S | 1 |
| Schüttler, J | 1 |
| Westhofen, P | 1 |
| Kania, U | 1 |
| Ihmsen, H | 1 |
| Kammerecker, S | 1 |
| Hirner, A | 1 |
| Sahin, A | 1 |
| Erçelen, O | 1 |
| Aypar, U | 1 |
| Erbengi, A | 1 |
| Matsota, P | 1 |
| Avgerinopoulou-Vlahou, A | 1 |
| Velegrakis, D | 1 |
| Tas, PW | 3 |
| Koschel, K | 3 |
| Kress, HG | 3 |
| Müller, J | 1 |
| Eisert, A | 1 |
| Eckhardt-Wallasch, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Association Between Changes in Cerebral Gray Matter Volume and Postoperative Cognitive Dysfunction in Elderly Patients Following Sevoflurane Anesthesia (POCD-MRI)[NCT02045004] | 100 participants (Actual) | Observational | 2015-07-14 | Completed | |||
| Release of Serum Neurofilament Light (NFL), Biomarker of Neuronal Injury, in Surgery Under General Anaesthesia (GA) Compared to Surgery With Hypno-analgesia (Hyp): A Prospective, Non-inferiority Study[NCT04500236] | 100 participants (Anticipated) | Interventional | 2020-09-01 | Recruiting | |||
| Evaluation of Stress Hormone Concentration During the Resection of Pheochromocytoma. Comparison of Surgeon - Anesthesiologist - Patient[NCT00948181] | 8 participants (Anticipated) | Observational | 2009-06-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for isoflurane and Pheochromocytoma
| Article | Year |
|---|---|
Variants of pheochromocytoma and their anesthetic implications--a case report and literature review.
Topics: Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Car | 2010 |
1 trial available for isoflurane and Pheochromocytoma
| Article | Year |
|---|---|
[Quantitative assessment of catecholamine secretion as a rational principle of anesthesia management in pheochromocytoma surgery].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Alfentanil; Anesthesia, General; Anesthesia, Intravenous | 1995 |
18 other studies available for isoflurane and Pheochromocytoma
| Article | Year |
|---|---|
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy | 2004 |
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy | 2004 |
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy | 2004 |
Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
Topics: Adrenal Gland Neoplasms; Amyloid beta-Peptides; Anesthetics, Inhalation; Animals; Central Nervous Sy | 2004 |
Desflurane and remifentanil use during resection of a cardiac pheochromocytoma.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Cardiopulmonary Bypass; Cathet | 2004 |
Anesthesia management with short acting agents for bilateral pheochromocytoma removal in a 12-year-old boy.
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, General; Ane | 2006 |
The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors.
Topics: Anesthetics, Inhalation; Animals; Animals, Genetically Modified; Annexin A5; Apoptosis; B-Lymphocyte | 2008 |
Effect of inhalational anesthetics on cytotoxicity and intracellular calcium differently in rat pheochromocytoma cells (PC12).
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Calcium; Cytoplasm; Desflurane; Inositol 1,4,5-Trisphos | 2008 |
Isoflurane anesthesia for resection of pheochromocytoma. A report of two cases.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Catecholamines; Child; Ephedrine; Epinephrine; Femal | 1984 |
Isoflurane for resection of pheochromocytomas.
Topics: Adrenal Gland Neoplasms; Anesthesia, Inhalation; Child, Preschool; Female; Humans; Isoflurane; Male; | 1983 |
Excision of pheochromocytoma under isoflurane anesthesia. A case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Inhalation; Female; Humans; Isoflurane; Methyl Ethers; P | 1983 |
Use of isoflurane during resection of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Arrhythmias, Cardiac; Catecholamines; Female; Humans; Intraoperative Compli | 1983 |
Removal of bilateral pheochromocytomas using isoflurane anesthesia, case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Inhalation; Female; Humans; Isoflurane; Methyl Ethers; P | 1982 |
Calcium channel blockade and uncontrolled blood pressure during phaeochromocytoma surgery.
Topics: Aged; Anesthesia, Inhalation; Blood Pressure; Cryosurgery; Diltiazem; Humans; Hypertension; Intraope | 1995 |
Use of desflurane during resection of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood Pres | 1994 |
Cerebral aneurysm surgery in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Anesthetics, Inhalation; Anesthetics, Intravenous; Antihypertensive Agents; | 1998 |
Anaesthesia for phaeochromocytoma removal in a 5-year-old boy.
Topics: Adjuvants, Anesthesia; Adrenal Gland Neoplasms; Anesthesia, General; Anesthetics, Inhalation; Anesth | 2002 |
Volatile anesthetics stimulate the phorbol ester evoked neurotransmitter release from PC12 cells through an increase of the cytoplasmic Ca2+ ion concentration.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Cytoplasm; Enflurane; Isoflurane; Kinetics; Me | 1991 |
Volatile anesthetics and stimulus-secretion coupling in a neural cell line.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Carbachol; Cell Line; Dopamine; Halothane; Isoflurane; Ki | 1991 |
Volatile anesthetics depress the depolarization-induced cytoplasmic calcium rise in PC 12 cells.
Topics: Adrenal Gland Neoplasms; Anesthetics; Animals; Benzofurans; Cell Line; Cytoplasm; Enflurane; Fluores | 1987 |
[Volatile anesthetics and n-alcohols inhibit the uptake of noradrenaline in pheochromocytoma cells].
Topics: Adrenal Gland Neoplasms; Alcohols; Anesthetics; Animals; Biological Transport; Cell Line; Enflurane; | 1987 |