isoflurane has been researched along with Pain in 100 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery." | 7.88 | Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018) |
| "F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms." | 7.73 | The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005) |
| "The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia." | 7.72 | Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004) |
| "After tracheal intubation and femoral arterial cannulation, bilateral neck dissections were performed to isolate the external carotid arteries and external jugular veins." | 5.29 | Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia? ( Antognini, JF; Borges, M, 1994) |
| "4%) or apnea (11 of 78, 14." | 5.19 | A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers. ( Huang, H; Li, R; Liao, T; Liu, J; Yi, X; Zhang, W, 2014) |
| "Propofol and isoflurane requirements and preoperative pain scores were not different between groups." | 5.17 | Comparison of perioperative analgesic efficacy between methadone and butorphanol in cats. ( Bauquier, SH; Beths, T; Holm, M; Warne, LN, 2013) |
| "The significant reduction in MAC of isoflurane supported the practice of the addition of regional anesthesia for painful dental procedures to reduce the dose-dependent cardiorespiratory effects of general anesthesia." | 5.17 | Effect of mepivacaine in an infraorbital nerve block on minimum alveolar concentration of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry. ( Snyder, CJ; Snyder, LB, 2013) |
| " Desflurane, with the characteristics of rapid onset and minimal metabolism, may provide better analgesia and safety for labour pain control." | 5.08 | Desflurane analgesia for vaginal delivery. ( Abboud, TK; Donovan, MM; Peres Da Silva, E; Swart, F; Yakal, K; Zhu, J, 1995) |
| " Clinical investigations have revealed that isoflurane anesthesia is efficient to alleviate pain during cardiac surgery, including heart bypass surgery." | 3.88 | Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. ( Lin, H; Pi, Z; Yang, J, 2018) |
| " In this study, we examined 3 commonly used euthanasia methods in mice: intraperitoneal injection of pentobarbital-phenytoin solution, CO2 inhalation, and isoflurane anesthesia followed by CO2 inhalation." | 3.85 | Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice. ( Boivin, GP; Bottomley, MA; Goss, L; Grobe, N; Schiml, PA, 2017) |
| " After having established the mice model of hypnosis and analgesia by intraperitoneal injections of appropriate doses of enflurane, isoflurane or sevoflurane, we intracerebroventricularly or intrathecally injected different doses of nicotine and then observed the effects on the sleeping time using awaken test and the pain threshold in hot-plate test (HPPT) using hot-plate test." | 3.75 | Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics. ( Dai, TJ; Yan, S; Zeng, YM, 2009) |
| "The experimental setup consisted of a randomized block design with four experimental groups: two light (3/4) minimum alveolar concentration (MAC) isoflurane anesthesia groups (unstimulated/NIWR-stimulated) and two NIWR-stimulated surgical anesthesia groups (1(1/2) MAC isoflurane anesthesia and (3/4) MAC isoflurane anesthesia combined with fentanyl 400-600 microg x kg(-1) x h(-1))." | 3.74 | Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl. ( Nguyen, NK; Ritskes-Hoitinga, M; Sommers, MG; van Egmond, J; Veening, JG; Vissers, KC, 2008) |
| " After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests." | 3.74 | Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007) |
| "F 13640 is a newly discovered high-efficacy 5-HT(1A) receptor agonist that produces exceptional analgesia in animal models of tonic and chronic, nociceptive and neuropathic pains by novel molecular and neuroadaptive mechanisms." | 3.73 | The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain. ( Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I, 2005) |
| "The authors previously reported changes in electroencephalographic bicoherence during isoflurane anesthesia combined with epidural anesthesia." | 3.72 | Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia. ( Hagihira, S; Mashimo, T; Mori, T; Takashina, M; Ueyama, H, 2004) |
| "The NMDA receptor and the NK-1 receptor are important determinants of the MAC of isoflurane, exerting this influence by inhibition of pain transmission in the spinal cord, while mGlu and AMPA receptors have no effect on the MAC of isoflurane." | 3.70 | Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats. ( Goto, F; Ishizaki, K; Karasawa, S; Nara, T; Obata, H; Sasaki, M, 1999) |
| "The purpose of this study was to examine the anaesthetic requirement of intrathecal midazolam in a dose-response fashion in isoflurane-anaesthetized, tracheostomized rats, and to evaluate the apnoeic threshold after each intrathecal midazolam dose." | 3.69 | Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats. ( Forster, A; Jorge-Costa, M; Morel, DR; Pizzolato, GP; Schwieger, IM, 1994) |
| "In 26 patients, the end-tidal and corresponding arterial isoflurane concentrations needed to suppress eye opening to verbal command and motor response after trapezius squeeze, 50 Hz electric tetanic stimulation, laryngoscopy, skin incision, and tracheal intubation in 50% of all patients were determined." | 3.69 | Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. I. Motor reactions. ( Lauber, R; Maggiorini, M; Minder, CE; Petersen-Felix, S; Thomson, DA; Zbinden, AM, 1994) |
| "Isoflurane used as a sole agent is unable to suppress hemodynamic reactions (blood pressure and heart rate) to painful stimuli." | 3.69 | Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. II. Hemodynamic responses. ( Petersen-Felix, S; Thomson, DA; Zbinden, AM, 1994) |
| "These results suggest that the NK-1 receptor plays an important role in determining the MAC of isoflurane by inhibition of pain transmission in the spinal cord." | 3.69 | Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats. ( Goto, F; Hasegawa, M; Ishizaki, K; Karasawa, S; Takahashi, K, 1997) |
| "Mice treated with ethyl chloride spray, isoflurane and buprenorphine, and 2-point local nerve blocks demonstrated increased tail-flick latency compared with that of untreated mice." | 2.77 | Evaluation of common anesthetic and analgesic techniques for tail biopsy in mice. ( Carver, S; Jones, CP; Kendall, LV, 2012) |
| "Isoflurane 0." | 2.67 | Isoflurane in labour. ( Hasan, MA; Thomas, TA; Wee, MY, 1993) |
| "Isoflurane is a useful agent for prolonged sedation of ventilated patients and does not have any adverse effect on the cardiorespiratory system or on hepatic, renal or adrenal function." | 2.67 | Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety. ( Spencer, EM; Willatts, SM, 1992) |
| "Isoflurane is a fluorinated ether used primarily as an inhalation anesthetic." | 2.39 | Providing comfort to critically ill pediatric patients: isoflurane. ( Curley, MA; Molengraft, JA, 1995) |
| "Our study suggests that approaches to activate the orexin system can be beneficial in postoperative recovery." | 1.48 | Activation of orexin system facilitates anesthesia emergence and pain control. ( Bickler, PE; Cheung, K; Guan, Z; Jan, LY; Kurien, PA; Kyu, S; Wang, L; Zhou, W, 2018) |
| "Intraoperative awareness and postoperative nausea/vomiting were assessed at follow-up." | 1.46 | Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude. ( Li, H; Peng, Q; Xu, R; Xu, S; Yang, J; Zhang, G; Zhang, Q; Zhou, S, 2017) |
| "Increasingly more aged people with Alzheimer's disease (AD) must undergo surgery with general anesthesia for various reasons." | 1.40 | Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice. ( Deng, Y; He, Z; Lu, B; Qi, B; Su, D; Tian, J; Wang, X; Xu, H; Zheng, B, 2014) |
| "Sevoflurane MAC was not significantly reduced by N2O and its antinociceptive action was almost completely abolished in KOP-knockout (KO) mice." | 1.40 | κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice. ( Fukagawa, H; Fukuda, K; Koyama, T, 2014) |
| "Isoflurane has been used as an inhaled anaesthetic for nearly 30 years." | 1.37 | Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord. ( Duan, QZ; Li, YQ; Liu, CR; Wang, W; Wei, YY; Wu, SX; Xu, LX; Zhang, H, 2011) |
| " This relatively simple blood collection technique seems to be efficient and safe in hamsters." | 1.35 | Efficiency and safety of a technique for drawing blood from the hamster cranial vena cava. ( Benito, PJ; García-Olmo, DC; Picazo, MG, 2009) |
| "Lidocaine was administered IV to each cat to achieve target pseudo-steady-state plasma concentrations of 0, 3, 5, 7 9, and 11 microg/mL, and isoflurane concentration was reduced to an equipotent concentration." | 1.33 | Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats. ( Ilkiw, JE; Pypendop, BH, 2005) |
| "Isoflurane MAC was not changed by intrathecal ondansetron in rats or systemically administered ondansetron in P-gp knockout mice." | 1.33 | The pronociceptive effect of ondansetron in the setting of P-glycoprotein inhibition. ( Flood, P; Scott, JA; Wood, M, 2006) |
| "Isoflurane was maintained at 0." | 1.31 | Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats. ( Antognini, JF; Carstens, E; Piercy, M; Wang, XW, 2000) |
| "After tracheal intubation and femoral arterial cannulation, bilateral neck dissections were performed to isolate the external carotid arteries and external jugular veins." | 1.29 | Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia? ( Antognini, JF; Borges, M, 1994) |
| "Isoflurane concentration was adjusted up and down, and the EEG and movement response to tail clamp were assessed at each level until the minimum alveolar concentration was determined in each rat." | 1.28 | No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats. ( Laster, MJ; Rampil, IJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.00) | 18.7374 |
| 1990's | 27 (27.00) | 18.2507 |
| 2000's | 39 (39.00) | 29.6817 |
| 2010's | 27 (27.00) | 24.3611 |
| 2020's | 4 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matta, JA | 1 |
| Cornett, PM | 1 |
| Miyares, RL | 1 |
| Abe, K | 1 |
| Sahibzada, N | 1 |
| Ahern, GP | 1 |
| Seyfi, S | 1 |
| Amiri, HA | 1 |
| Banihashem, N | 1 |
| Ezoji, K | 1 |
| Ziaei, SG | 1 |
| Davis, JA | 1 |
| Bopp, AC | 1 |
| Henwood, MK | 1 |
| Bean, P | 1 |
| Grau, JW | 1 |
| Lykholt, LED | 1 |
| Mørch, CD | 1 |
| Jensen, W | 1 |
| Shirai, T | 1 |
| Yano, M | 1 |
| Natsume, T | 1 |
| Awaga, Y | 1 |
| Itani, Y | 1 |
| Hama, A | 1 |
| Matsuda, A | 1 |
| Takamatsu, H | 1 |
| Boivin, GP | 1 |
| Bottomley, MA | 1 |
| Schiml, PA | 1 |
| Goss, L | 1 |
| Grobe, N | 1 |
| Ryu, K | 1 |
| Song, K | 1 |
| Kim, J | 3 |
| Kim, E | 1 |
| Kim, SH | 1 |
| Pi, Z | 1 |
| Lin, H | 1 |
| Yang, J | 2 |
| Zhou, W | 1 |
| Cheung, K | 1 |
| Kyu, S | 1 |
| Wang, L | 1 |
| Guan, Z | 1 |
| Kurien, PA | 1 |
| Bickler, PE | 1 |
| Jan, LY | 1 |
| Voigt, AM | 1 |
| Bergfeld, C | 1 |
| Beyerbach, M | 1 |
| Kästner, SB | 1 |
| Warne, LN | 1 |
| Beths, T | 1 |
| Holm, M | 1 |
| Bauquier, SH | 1 |
| Xu, H | 1 |
| Lu, B | 1 |
| Zheng, B | 1 |
| Tian, J | 1 |
| Qi, B | 1 |
| Deng, Y | 1 |
| He, Z | 1 |
| Su, D | 1 |
| Wang, X | 1 |
| Huang, H | 1 |
| Li, R | 1 |
| Liu, J | 1 |
| Zhang, W | 1 |
| Liao, T | 1 |
| Yi, X | 1 |
| Sadler, KE | 1 |
| Stratton, JM | 1 |
| DeBerry, JJ | 1 |
| Kolber, BJ | 1 |
| Fan, HG | 1 |
| Jiang, S | 1 |
| Lin, DQ | 1 |
| Lu, DZ | 1 |
| Li, L | 1 |
| Ji, W | 1 |
| Li, WZ | 1 |
| Fukagawa, H | 1 |
| Koyama, T | 1 |
| Fukuda, K | 2 |
| Wang, LW | 1 |
| Zhou, MY | 1 |
| Jian, HW | 1 |
| Dai, TJ | 4 |
| Jaber, SM | 1 |
| Sullivan, S | 1 |
| Hankenson, FC | 1 |
| Kilbaugh, TJ | 1 |
| Margulies, SS | 1 |
| Kim, HC | 1 |
| Hong, WP | 1 |
| Lim, YJ | 1 |
| Park, HP | 1 |
| Barletta, M | 1 |
| Quandt, J | 1 |
| Hofmeister, E | 1 |
| Xu, R | 1 |
| Zhou, S | 1 |
| Li, H | 1 |
| Zhang, Q | 1 |
| Zhang, G | 1 |
| Xu, S | 1 |
| Peng, Q | 1 |
| Ge, ZJ | 1 |
| Tan, YF | 1 |
| Zhao, YP | 1 |
| Cui, GX | 1 |
| Asanuma, T | 1 |
| Yasui, H | 1 |
| Sato, M | 1 |
| Inanami, O | 1 |
| Kuwabara, M | 1 |
| Yan, S | 1 |
| Zeng, YM | 4 |
| Cheng, W | 1 |
| Yin, Q | 1 |
| Wang, S | 1 |
| Chen, HS | 1 |
| Feng, T | 1 |
| Picazo, MG | 1 |
| Benito, PJ | 1 |
| García-Olmo, DC | 1 |
| Pham, TM | 1 |
| Hagman, B | 1 |
| Codita, A | 1 |
| Van Loo, PL | 1 |
| Strömmer, L | 1 |
| Baumans, V | 1 |
| Guan, Y | 1 |
| Raja, SN | 1 |
| Liu, CR | 1 |
| Duan, QZ | 1 |
| Wang, W | 1 |
| Wei, YY | 1 |
| Zhang, H | 1 |
| Li, YQ | 1 |
| Wu, SX | 1 |
| Xu, LX | 1 |
| Kung, HH | 1 |
| Hsu, SF | 1 |
| Hung, YC | 1 |
| Chen, KB | 1 |
| Chen, JY | 1 |
| Wen, YR | 1 |
| Sun, WZ | 1 |
| Walker, KA | 1 |
| Mellish, JE | 1 |
| Weary, DM | 1 |
| Shu, Y | 1 |
| Zhou, Z | 1 |
| Wan, Y | 1 |
| Sanders, RD | 1 |
| Li, M | 1 |
| Pac-Soo, CK | 1 |
| Maze, M | 1 |
| Ma, D | 1 |
| Young, MJ | 1 |
| Alston, TA | 1 |
| Valentine, H | 1 |
| Williams, WO | 1 |
| Maurer, KJ | 1 |
| Moldal, ER | 1 |
| Kirpensteijn, J | 1 |
| Kristensen, AT | 1 |
| Haga, HA | 1 |
| Nødtvedt, A | 1 |
| Eriksen, T | 1 |
| Snyder, CJ | 1 |
| Snyder, LB | 1 |
| Jones, CP | 1 |
| Carver, S | 1 |
| Kendall, LV | 1 |
| Jinks, SL | 3 |
| Antognini, JF | 14 |
| Martin, JT | 1 |
| Jung, S | 1 |
| Carstens, E | 10 |
| Atherley, R | 3 |
| Eger, EI | 3 |
| Xing, Y | 1 |
| Laster, MJ | 2 |
| Sonner, JM | 2 |
| Valverde, A | 1 |
| Morey, TE | 1 |
| Hernández, J | 1 |
| Davies, W | 1 |
| Hagihira, S | 1 |
| Takashina, M | 1 |
| Mori, T | 1 |
| Ueyama, H | 1 |
| Mashimo, T | 2 |
| Stekiel, TA | 1 |
| J Contney, S | 1 |
| Bosnjak, ZJ | 1 |
| Kampine, JP | 1 |
| Roman, RJ | 1 |
| Stekiel, WJ | 1 |
| Rowley, TJ | 1 |
| Daniel, D | 1 |
| Flood, P | 3 |
| Pypendop, BH | 1 |
| Ilkiw, JE | 1 |
| Kiss, I | 1 |
| Degryse, AD | 1 |
| Bardin, L | 1 |
| Gomez de Segura, IA | 1 |
| Colpaert, FC | 1 |
| Spadavecchia, C | 1 |
| Levionnois, O | 1 |
| Kronen, PW | 1 |
| Leandri, M | 1 |
| Spadavecchia, L | 1 |
| Schatzmann, U | 1 |
| Scott, JA | 1 |
| Wood, M | 1 |
| Mitsuyo, T | 1 |
| Dutton, RC | 1 |
| Hayashida, M | 1 |
| Fukunaga, A | 1 |
| Sakurai, S | 1 |
| Mamiya, H | 1 |
| Ichinohe, T | 1 |
| Kaneko, Y | 1 |
| Hanaoka, K | 1 |
| Vahle-Hinz, C | 1 |
| Detsch, O | 1 |
| Hackner, C | 1 |
| Kochs, E | 1 |
| Otto, KA | 1 |
| Chen, Y | 1 |
| Werner, DF | 1 |
| Homanics, GE | 1 |
| Lin, CM | 1 |
| Wu, CT | 1 |
| Lee, ST | 1 |
| Lui, TN | 1 |
| Huang, CC | 1 |
| Li, AH | 1 |
| Doufas, AG | 1 |
| Hang, LH | 1 |
| Shao, DH | 1 |
| Yang, YH | 1 |
| Yao, A | 1 |
| Ihmsen, H | 1 |
| Schywalsky, M | 1 |
| Plettke, R | 1 |
| Priller, M | 1 |
| Walz, F | 1 |
| Schwilden, H | 1 |
| Sommers, MG | 1 |
| Nguyen, NK | 1 |
| Veening, JG | 1 |
| Vissers, KC | 1 |
| Ritskes-Hoitinga, M | 1 |
| van Egmond, J | 1 |
| Shaw, MV | 1 |
| Naff, KA | 1 |
| LeBlanc, S | 1 |
| Swing, SP | 1 |
| Roberts, JS | 1 |
| O'Donnell, D | 1 |
| Emerson, C | 1 |
| Berg, K | 1 |
| Kien, ND | 1 |
| Curley, MA | 1 |
| Molengraft, JA | 1 |
| Petersen-Felix, S | 4 |
| Arendt-Nielsen, L | 2 |
| Bak, P | 2 |
| Roth, D | 1 |
| Fischer, M | 2 |
| Bjerring, P | 2 |
| Zbinden, AM | 4 |
| Abboud, TK | 1 |
| Swart, F | 1 |
| Zhu, J | 1 |
| Donovan, MM | 1 |
| Peres Da Silva, E | 1 |
| Yakal, K | 1 |
| Lysko, GS | 1 |
| Robinson, JL | 1 |
| Casto, R | 1 |
| Ferrone, RA | 1 |
| Borges, M | 1 |
| Abram, SE | 1 |
| Olson, EE | 1 |
| Schwieger, IM | 1 |
| Jorge-Costa, M | 1 |
| Pizzolato, GP | 1 |
| Forster, A | 1 |
| Morel, DR | 1 |
| Maggiorini, M | 1 |
| Lauber, R | 1 |
| Thomson, DA | 2 |
| Minder, CE | 1 |
| Wee, MY | 1 |
| Hasan, MA | 1 |
| Thomas, TA | 1 |
| Tomi, K | 1 |
| Tashiro, C | 1 |
| Yagi, M | 1 |
| Pak, M | 1 |
| Nishimura, S | 1 |
| Nishimura, M | 1 |
| Yoshiya, I | 1 |
| Ishizaki, K | 2 |
| Karasawa, S | 2 |
| Takahashi, K | 1 |
| Hasegawa, M | 1 |
| Goto, F | 2 |
| Sonner, J | 1 |
| Li, J | 1 |
| Yost, CS | 1 |
| Hampson, AJ | 1 |
| Leonoudakis, D | 1 |
| Koblin, DD | 1 |
| Bornheim, LM | 1 |
| Gray, AT | 1 |
| Chae, BK | 1 |
| Lee, HW | 1 |
| Sun, K | 1 |
| Choi, YH | 1 |
| Kim, HM | 1 |
| Saitoh, Y | 1 |
| Fujii, Y | 1 |
| Makita, K | 1 |
| Tanaka, H | 1 |
| Amaha, K | 1 |
| Ben-Shlomo, I | 1 |
| Moskovich, R | 1 |
| Katz, Y | 1 |
| Shalev, E | 1 |
| Sasaki, M | 1 |
| Obata, H | 1 |
| Nara, T | 1 |
| Dahan, A | 1 |
| Teppema, L | 1 |
| Wang, XW | 3 |
| Piercy, M | 1 |
| Masaki, E | 1 |
| Ebisawa, T | 1 |
| Kondo, I | 1 |
| Hayashida, K | 1 |
| Matsumoto, Y | 1 |
| Kawamura, M | 1 |
| Sudo, M | 1 |
| Sudo, S | 1 |
| Zhang, Y | 1 |
| Laster, M | 1 |
| Kendig, JJ | 1 |
| Machin, KL | 1 |
| Livingston, A | 1 |
| Rampil, IJ | 1 |
| Spencer, EM | 1 |
| Willatts, SM | 1 |
| Ghouri, AF | 1 |
| Bodner, M | 1 |
| White, PF | 1 |
| Gibbs, NM | 1 |
| Larach, DR | 1 |
| Schuler, HG | 1 |
| Wren, WS | 1 |
| Alteri, S | 1 |
| Beruschi, M | 1 |
| Bolli, L | 1 |
| Fazio, R | 1 |
| Maddaloni, G | 1 |
| Mammarella, M | 1 |
| Mammini, R | 1 |
| Paesani, G | 1 |
| Poli, P | 1 |
| Riccardi, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Effects of Sevoflurane and Desflurane on Prevention of Catheter-related Bladder Discomfort[NCT02096224] | 108 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Topical Analgesia Before Inhalational Anaesthesia: A Retrospective Observational Study[NCT04959409] | 500 participants (Actual) | Observational | 2020-08-01 | Completed | |||
| EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers[NCT05701748] | 120 participants (Anticipated) | Interventional | 2023-02-03 | Recruiting | |||
| Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374] | Phase 3 | 272 participants (Actual) | Interventional | 2018-02-08 | Completed | ||
| Effect of Perioperative Epidural Block and Dexamethasone on Outcome of Patients Undergoing Pancreatic Cancer Surgery: a 2×2 Factorial Randomized Controlled Trial[NCT04025840] | Phase 4 | 260 participants (Anticipated) | Interventional | 2019-09-11 | Recruiting | ||
| Effect of Transversus Abdominis Plane (TAP) Block and the Perioperative Stress Response: Randomized Control Trial in Patient Undergoing Total Abdominal Hysterectomy in a Tertiary Care Hospital of Pakistan[NCT03443271] | Phase 4 | 50 participants (Actual) | Interventional | 2016-06-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for isoflurane and Pain
| Article | Year |
|---|---|
Providing comfort to critically ill pediatric patients: isoflurane.
Topics: Child; Conscious Sedation; Drug Monitoring; Humans; Intensive Care Units, Pediatric; Isoflurane; Pai | 1995 |
24 trials available for isoflurane and Pain
| Article | Year |
|---|---|
An Investigation Into Quality of Recovery After General Anesthesia With Isoflurane and Propofol in Patients Undergoing Abdominal Hysterectomy.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Female; Humans; Hysterect | 2022 |
Comparison of the Analgesic Properties of Sevoflurane and Desflurane Using Surgical Pleth Index at Equi-Minimum Alveolar Concentration.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Arthroscopy; Brachial Plexus Block; Desflura | 2017 |
Effects of isoflurane with and without dexmedetomidine or remifentanil on heart rate variability before and after nociceptive stimulation at different multiples of minimum alveolar concentration in dogs.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, | 2013 |
Comparison of perioperative analgesic efficacy between methadone and butorphanol in cats.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Butorphanol; Cat Disea | 2013 |
A phase I, dose-escalation trial evaluating the safety and efficacy of emulsified isoflurane in healthy human volunteers.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Apnea; Cohort Studies; Dose-Response Relati | 2014 |
Comparison of anaesthetic and analgesic effects of emulsified isoflurane used alone or combined with lidocaine and fentanyl in dogs.
Topics: Analgesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Dogs; Dru | 2014 |
The effect of sevoflurane versus desflurane on postoperative catheter-related bladder discomfort in patients undergoing transurethral excision of a bladder tumour: a randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Desflurane; Female; Humans; Incidence; Isofluran | 2016 |
Determination of minimum alveolar concentration of isoflurane in dogs and cats using the up-and-down method. A preliminary study.
Topics: Anesthetics, Inhalation; Animals; Cats; Dogs; Dose-Response Relationship, Drug; Female; Isoflurane; | 2016 |
Evaluation of inflammatory and hemostatic surgical stress responses in male cats after castration under general anesthesia with or without local anesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Local; Anesthetics, Local; Animals; Cats; I | 2012 |
Effect of mepivacaine in an infraorbital nerve block on minimum alveolar concentration of isoflurane in clinically normal anesthetized dogs undergoing a modified form of dental dolorimetry.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Animals; Dogs; Dose-Response Re | 2013 |
Evaluation of common anesthetic and analgesic techniques for tail biopsy in mice.
Topics: Analgesics; Anesthetics; Animals; Animals, Outbred Strains; Behavior, Animal; Biopsy; Bupivacaine; B | 2012 |
Validation of several types of noxious stimuli for use in determining the minimum alveolar concentration for inhalation anesthetics in dogs and rabbits.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dogs; Dose-Response Relationship, Drug; El | 2003 |
Evaluation of administration of isoflurane at approximately the minimum alveolar concentration on depression of a nociceptive withdrawal reflex evoked by transcutaneous electrical stimulation in ponies.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Electric Stimulation; Horses; Isoflurane; | 2006 |
Effects of averaging data series on the electroencephalographic response to noxious visceral stimulation in isoflurane-anaesthetized dogs.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Dogs; Electric Stimulation | 2007 |
Sitting position does not alter minimum alveolar concentration for desflurane.
Topics: Adult; Algorithms; Anesthetics, Inhalation; Blood Pressure; Computer Simulation; Data Interpretation | 2007 |
Analgesic effect in humans of subanaesthetic isoflurane concentrations evaluated by experimentally induced pain.
Topics: Adult; Analgesia; Anesthetics, Inhalation; Cold Temperature; Dose-Response Relationship, Drug; Femal | 1995 |
Desflurane analgesia for vaginal delivery.
Topics: Acid-Base Equilibrium; Adaptation, Physiological; Adult; Analgesia, Obstetrical; Anesthetics, Inhala | 1995 |
Isoflurane in labour.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Drug Combinations; Female; | 1993 |
The effects of isoflurane on repeated nociceptive stimuli (central temporal summation).
Topics: Adult; Anesthetics, Inhalation; Electric Stimulation; Electromyography; Female; Humans; Isoflurane; | 1996 |
Modified double burst stimulation of varying stimulating currents.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Electric Stimulati | 1998 |
Midazolam/ketamine sedative combination compared with fentanyl/propofol/isoflurane anaesthesia for oocyte retrieval.
Topics: Adult; Anesthesia, General; Anesthetics; Female; Fentanyl; Humans; Hypnotics and Sedatives; Isoflura | 1999 |
Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Drug Monitoring; England; Female; Hemo | 1992 |
Recovery profile after desflurane-nitrous oxide versus isoflurane-nitrous oxide in outpatients.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhalation; Cognition | 1991 |
[Evaluation of analgesic protection using RIA determination of prolactin, ACTH, cortisol and aldosterone during general anesthesia with enflurane-isoflurane and buprenorphine].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Anesthesia, General; Buprenorphine; Enflurane; Fema | 1987 |
75 other studies available for isoflurane and Pain
| Article | Year |
|---|---|
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation.
Topics: Anesthetics, General; Animals; Ankyrins; Calcium Channels; Humans; Inflammation; Isoflurane; Mice; P | 2008 |
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba | 2023 |
Differences in intracortical responses following non-noxious and noxious stimulation in anaesthetized rats.
Topics: Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Isoflurane; Pain; Physical Stimulation | 2023 |
Pharmacologic Modulation of Noxious Stimulus-evoked Brain Activation in Cynomolgus Macaques Observed with Functional Neuroimaging.
Topics: Analgesia; Analgesics; Animals; Brain; Female; Functional Neuroimaging; Isoflurane; Macaca fascicula | 2020 |
Physiologic, Behavioral, and Histologic Responses to Various Euthanasia Methods in C57BL/6NTac Male Mice.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Carbon Dioxide; Euthanasia, Animal; Hypnotics and Seda | 2017 |
Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery.
Topics: Animals; Apoptosis; Coronary Artery Bypass; Isoflurane; Male; Mice; Myocardial Ischemia; Myocardium; | 2018 |
Activation of orexin system facilitates anesthesia emergence and pain control.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Clozapine; Dependovirus; Electroenceph | 2018 |
Smaller sized inhaled anesthetics have more potency on senescence-accelerated prone-8 mice compared with senescence-resistant-1 mice.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Anesthetics, Inhalation; Animals; Desflurane; Diseas | 2014 |
Optimization of a pain model: effects of body temperature and anesthesia on bladder nociception in mice.
Topics: Anesthesia; Animals; Body Temperature; Disease Models, Animal; Electrophysiological Phenomena; Femal | 2013 |
κ-Opioid receptor mediates the antinociceptive effect of nitrous oxide in mice.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Isoflurane; Lumbar Vertebrae; Methyl Eth | 2014 |
Relationship between gamma-hydroxybutyric acid receptors and the hypnotic and analgesic effects of emulsified inhalation anesthetics.
Topics: Analgesics; Anesthetics, Inhalation; Animals; Benzocycloheptenes; Enflurane; Female; Hot Temperature | 2014 |
Comparison of Heart Rate and Blood Pressure with Toe Pinch and Bispectral Index for Monitoring the Depth of Anesthesia in Piglets.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Biomedical Research; Blood Pressure; Female; Heart Rat | 2015 |
Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude.
Topics: Adolescent; Adult; Altitude; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhal | 2017 |
Evidence that inhibition of spinal nitric oxide production contributes to the antinociceptive effects of emulsified isoflurane on formalin-induced pain in rats.
Topics: Analgesics; Animals; Emulsifying Agents; Female; Injections, Spinal; Isoflurane; Male; Nitric Oxide; | 2008 |
A BOLD-fMRI study of cerebral activation induced by injection of algesic chemical substances into the anesthetized rat forepaw.
Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Forelimb; Formaldehyde; Isoflurane; Magnetic R | 2008 |
Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics.
Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; Female; In | 2009 |
Effects of intrathecal injection of nicotine on the analgesic effects of isoflurane in a model of inflammatory pain.
Topics: Analgesics; Animals; Formaldehyde; Injections, Spinal; Isoflurane; Mice; Nicotine; Pain; Pain Thresh | 2009 |
Efficiency and safety of a technique for drawing blood from the hamster cranial vena cava.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cricetinae; Female; Isoflurane; Male; Mesocricetus; Pa | 2009 |
Housing environment influences the need for pain relief during post-operative recovery in mice.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Behavior, Animal; Body Weight; Disease M | 2010 |
Wide-dynamic-range neurons are heterogeneous in windup responsiveness to changes in stimulus intensity and isoflurane anesthesia level in mice.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Electric Stimulation; Isoflurane; Male; Mice; M | 2010 |
Effects of intrathecal isoflurane administration on nociception and Fos expression in the rat spinal cord.
Topics: Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Exp | 2011 |
Electroacupuncture analgesia, stress responses, and variations in sensitivity in rats anesthetized with different sub-MAC anesthetics.
Topics: Analgesia; Anesthetics, Inhalation; Animals; Blood Pressure; Electroacupuncture; Halothane; Heart Ra | 2011 |
Effects of hot-iron branding on heart rate, breathing rate and behaviour of anaesthetised Steller sea lions.
Topics: Anesthetics, Inhalation; Animal Identification Systems; Animal Welfare; Animals; Behavior, Animal; F | 2011 |
Nociceptive stimuli enhance anesthetic-induced neuroapoptosis in the rat developing brain.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blotting, Western; | 2012 |
Does anesthetic technique influence cancer?
Topics: Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Female; Humans; I | 2012 |
Sedation or inhalant anesthesia before euthanasia with CO2 does not reduce behavioral or physiologic signs of pain and stress in mice.
Topics: Acepromazine; Adrenocorticotropic Hormone; Anesthesia; Animal Welfare; Animals; Animals, Laboratory; | 2012 |
Isoflurane, but not halothane, depresses c-fos expression in rat spinal cord at concentrations that suppress reflex movement after supramaximal noxious stimulation.
Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Halothane; Immunohistochemistry; | 2002 |
Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Im | 2003 |
Isoflurane depresses diffuse noxious inhibitory controls in rats between 0.8 and 1.2 minimum alveolar anesthetic concentration.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Cold Temperature; Dose-Response Relationship, D | 2003 |
Electroencephalographic bicoherence is sensitive to noxious stimuli during isoflurane or sevoflurane anesthesia.
Topics: Adult; Aged; Anesthesia; Anesthetics, Inhalation; Electroencephalography; Female; Fentanyl; Humans; | 2004 |
Reversal of minimum alveolar concentrations of volatile anesthetics by chromosomal substitution.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Chromosomes; Gene Transfer Techniques; Haloth | 2004 |
The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement.
Topics: Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Inhalation; Animals; Benzylamines; Dopamine; | 2005 |
Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Blood Pressure; Cats | 2005 |
The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthetics, Inhalati | 2005 |
The pronociceptive effect of ondansetron in the setting of P-glycoprotein inhibition.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Female; Isoflurane; Male; Mice; Mi | 2006 |
The differential effects of halothane and isoflurane on windup of dorsal horn neurons selected in unanesthetized decerebrated rats.
Topics: Anesthetics, Inhalation; Animals; Area Under Curve; Dose-Response Relationship, Drug; Halothane; Iso | 2006 |
The characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil.
Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon | 2006 |
Corresponding minimum alveolar concentrations of isoflurane and isoflurane/nitrous oxide have divergent effects on thalamic nociceptive signalling.
Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Drug Synergism; Hot Temperature; Isoflurane | 2007 |
Strychnine-sensitive glycine receptors mediate the analgesic but not hypnotic effects of emulsified volatile anesthetics.
Topics: Analgesia; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; | 2007 |
Isoflurane depression of spinal nociceptive processing and minimum alveolar anesthetic concentration are not attenuated in mice expressing isoflurane resistant gamma-aminobutyric acid type-A receptors.
Topics: Anesthetics, Inhalation; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Resis | 2007 |
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha | 2007 |
Neurons in the ventral spinal cord are more depressed by isoflurane, halothane, and propofol than are neurons in the dorsal spinal cord.
Topics: Action Potentials; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animal | 2007 |
Concentration-effect relations, prediction probabilities (Pk), and signal-to-noise ratios of different electroencephalographic parameters during administration of desflurane, isoflurane, and sevoflurane in rats.
Topics: Animals; Brain; Cross-Over Studies; Desflurane; Electric Stimulation; Electroencephalography; Isoflu | 2008 |
Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl.
Topics: Analgesics; Anesthesia; Animals; Drug Therapy, Combination; Electric Stimulation; Fentanyl; Isoflura | 2008 |
Compensating for a lack of skill. Response to Protocol Review scenario: poor methodology.
Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani | 2008 |
Compensating for a lack of skill.
Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani | 2008 |
Compensating for a lack of skill. Response to Protocol Review scenario: try more training first.
Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani | 2008 |
Compensating for a lack of skill. Response to Protocol Review scenario: not at our institute!
Topics: Anesthesia; Anesthetics, Inhalation; Animal Care Committees; Animal Technicians; Animal Welfare; Ani | 2008 |
Cardiovascular responses to noxious stimuli during isoflurane anesthesia are minimally affected by anesthetic action in the brain.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Brain; Goats; Heart Rate; Isoflurane; Pain | 1995 |
Potency (minimum alveolar anesthetic concentration) of isoflurane is independent of peripheral anesthetic effects.
Topics: Anesthesia, Inhalation; Animals; Aorta; Axons; Blood Circulation; Catheterization; Dogs; Hindlimb; I | 1995 |
The stereospecific effects of isoflurane isomers in vivo.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Animals; Blood Pressure; Dose-Response Relations | 1994 |
Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia?
Topics: Anesthesia; Animals; Blood Gas Analysis; Blood Glucose; Brain; Dose-Response Relationship, Drug; Goa | 1994 |
Systemic opioids do not suppress spinal sensitization after subcutaneous formalin in rats.
Topics: Alfentanil; Animals; Drug Administration Schedule; Formaldehyde; Hot Temperature; Hyperalgesia; Inje | 1994 |
Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats.
Topics: Anesthesia, Spinal; Animals; Apnea; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug | 1994 |
Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. I. Motor reactions.
Topics: Adult; Anesthesia, Inhalation; Anesthesiology; Female; Humans; Isoflurane; Male; Middle Aged; Motor | 1994 |
Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. II. Hemodynamic responses.
Topics: Adult; Anesthesia, Inhalation; Anesthesiology; Blood Pressure; Female; Heart Rate; Hemodynamics; Hum | 1994 |
Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans.
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Halothane; Humans; Isoflurane; Male; | 1993 |
The relationship among brain, spinal cord and anesthetic requirements.
Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Brain; Electromyography; Goats; Humans; Isofl | 1997 |
Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats.
Topics: Anesthetics, Inhalation; Animals; Biphenyl Compounds; Excitatory Amino Acid Antagonists; Isoflurane; | 1997 |
Desflurane and nitrous oxide, but not nonimmobilizers, affect nociceptive responses.
Topics: Animals; Chlorofluorocarbons; Cyclobutanes; Desflurane; Dose-Response Relationship, Drug; Fluorocarb | 1998 |
Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration.
Topics: Anesthetics, Inhalation; Animals; Benzodiazepines; Cerebrosides; Chloride Channels; Desflurane; Drug | 1998 |
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be | 1998 |
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be | 1998 |
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be | 1998 |
The effect of combined epidural and light general anesthesia on stress hormones in open heart surgery patients.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; be | 1998 |
Intrathecal co-administration of NMDA antagonist and NK-1 antagonist reduces MAC of isoflurane in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Anesthetics, Inhalation; Animals; Biphenyl Compounds; | 1999 |
Isoflurane blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cerebral Cortex; Cortical Synchronization; | 1999 |
Influence of low-dose anaesthetic agents on ventilatory control: where do we stand?
Topics: Anesthetics, Inhalation; Arousal; Depression, Chemical; Humans; Isoflurane; Methyl Ethers; Pain; Res | 1999 |
Isoflurane action in the spinal cord blunts electroencephalographic and thalamic-reticular formation responses to noxious stimulation in goats.
Topics: Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Glucose; Electric Stimulation; Electrode | 2000 |
Propofol directly depresses lumbar dorsal horn neuronal responses to noxious stimulation in goats.
Topics: Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Central Ner | 2000 |
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain; | 2000 |
Isoflurane anaesthetic depth in goats monitored using the bispectral index of the electroencephalogram.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Electroencephalography; Female; Goats; Intubation, Int | 2000 |
Isoflurane depresses electroencephalographic and medial thalamic responses to noxious stimulation via an indirect spinal action.
Topics: Anesthetics, Inhalation; Animals; Depression, Chemical; Electroencephalography; Evoked Potentials; F | 2000 |
Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Atropine; Cholinergic Antagonists; Injections, Intraperitoneal; In | 2002 |
Assessment of the analgesic effects of ketoprofen in ducks anesthetized with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Ducks | 2002 |
No correlation between quantitative electroencephalographic measurements and movement response to noxious stimuli during isoflurane anesthesia in rats.
Topics: Anesthesia, Inhalation; Animals; Electrocardiography; Female; Isoflurane; Male; Movement; Pain; Rats | 1992 |
The effect of neuromuscular blockade with vecuronium on hemodynamic responses to noxious stimuli in the rat.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Halothane; Heart Rate; Hemodynamics; Isoflurane; Ma | 1989 |
Anaesthetic technique and pain in the newborn.
Topics: Anesthesia; Fentanyl; Humans; Immune Tolerance; Infant, Newborn; Isoflurane; Pain | 1989 |