isoflurane has been researched along with Nociceptive Pain in 4 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mepivacaine horses were given mepivacaine 2% (3." | 2.87 | Local mepivacaine before castration of horses under medetomidine isoflurane balanced anaesthesia is effective to reduce perioperative nociception and cytokine release. ( Abass, M; Bettschart-Wolfensberger, R; Garzón, JFG; Kühnle, C; Picek, S; Zaghlou, A, 2018) |
| "Opioid receptor antagonists increase hyperalgesia in humans and animals, which indicates that endogenous activation of opioid receptors provides relief from acute pain; however, the mechanisms of long-term opioid inhibition of pathological pain have remained elusive." | 1.39 | Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. ( Corder, G; Donahue, RR; Doolen, S; He, Y; Hu, X; Jutras, BL; McCarson, KE; Mogil, JS; Storm, DR; Taylor, BK; Wang, ZJ; Wieskopf, JS; Winter, MK, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raithel, SJ | 1 |
| Sapio, MR | 1 |
| Iadarola, MJ | 1 |
| Mannes, AJ | 1 |
| Abass, M | 1 |
| Picek, S | 1 |
| Garzón, JFG | 1 |
| Kühnle, C | 1 |
| Zaghlou, A | 1 |
| Bettschart-Wolfensberger, R | 1 |
| Corder, G | 1 |
| Doolen, S | 1 |
| Donahue, RR | 1 |
| Winter, MK | 1 |
| Jutras, BL | 1 |
| He, Y | 1 |
| Hu, X | 1 |
| Wieskopf, JS | 1 |
| Mogil, JS | 1 |
| Storm, DR | 1 |
| Wang, ZJ | 1 |
| McCarson, KE | 1 |
| Taylor, BK | 1 |
| Uchida, S | 1 |
| Bois, S | 1 |
| Guillemot, JP | 1 |
| Leblond, H | 1 |
| Piché, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury. A Randomized, Placebo-controlled, Double-blind Crossover Study[NCT02684669] | Phase 2 | 80 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperal-gesia in Patients Following Recovery From Impacted Mandibular Third Molar Extraction. A Randomized, Placebo-controlled, Double-blind Crossover Study.[NCT02976337] | Phase 2 | 14 participants (Anticipated) | Interventional | 2017-10-12 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for isoflurane and Nociceptive Pain
| Article | Year |
|---|---|
Local mepivacaine before castration of horses under medetomidine isoflurane balanced anaesthesia is effective to reduce perioperative nociception and cytokine release.
Topics: Analgesics; Anesthesia; Anesthetics, Local; Animals; Arterial Pressure; Cardiotonic Agents; Clonixin | 2018 |
3 other studies available for isoflurane and Nociceptive Pain
| Article | Year |
|---|---|
Thermal A-δ Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Anim | 2018 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.
Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Anima | 2013 |
Systemic blood pressure alters cortical blood flow and neurovascular coupling during nociceptive processing in the primary somatosensory cortex of the rat.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Cerebrovascular Circulation; Electric Stimulation; | 2017 |